Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8323 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- MAPKAP1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human MAPKAP1.
- Description
- Mitogen-activated protein kinase associated protein 1 (MAPKAP-1) is a protein that localizes in the nucleus and is involved in several different signal transduction pathways. MAPKAP-1 contains one stress-activated map kinase interacting 1 domain (Pfam), a 2nd peroximal domain, and an ER membrane domain (Psort2). MAPKAP-1 binds to and inhibits c-Jun N-terminal kinase (JNK), and may act as a scaffold molecule in the regulation of JNK signaling. Transcription of the MAPKAP-1 gene is activated any time the organism is wounded, and stress to the cell causes the MAPKAP-1 protein to be phosphorylated. Cells lacking this protein may display sterility, multiple stress sensitivity, and a cell-cycle delay.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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