APR06649G
SCUBE1 antibody from Leading Biology
- Western blot
Recommended by provider
- Immunocytochemistry
- Recommended by provider
Antibody data
- Antibody Data
- Knockdown Reagents [0]
- References [0]
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- Validations [0]
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- Product number
- APR06649G
- Provider
- Leading Biology
- Product name
- SCUBE1 Antibody
- Provider product page
- Leading Biology - APR06649G
- Antibody type
- Polyclonal
- Description
- SCUBE1 Antibody: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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