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- References [10]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16177-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16177-1-AP, RRID:AB_2135038
- Product name
- Lin28A-specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Lin28A-specific antibody (Cat. #16177-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer.
Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate.
LIN28A enhances regenerative capacity of human somatic tissue stem cells via metabolic and mitochondrial reprogramming.
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition.
Lin28A promotes IRF6-regulated aerobic glycolysis in glioma cells by stabilizing SNHG14.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A.
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts.
Si X, Zhang G, Li M, Yao M, Shi X, Dong Z, Gao S
Pharmacology 2023;108(1):61-73
Pharmacology 2023;108(1):61-73
Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate.
Jia S, Zhang Q, Wang Y, Wei X, Gu H, Liu D, Ma W, He Y, Luo W, Yuan Z
Annals of the New York Academy of Sciences 2022 Oct;1516(1):234-246
Annals of the New York Academy of Sciences 2022 Oct;1516(1):234-246
LIN28A enhances regenerative capacity of human somatic tissue stem cells via metabolic and mitochondrial reprogramming.
Pieknell K, Sulistio YA, Wulansari N, Darsono WHW, Chang MY, Ko JY, Chang JW, Kim MJ, Lee MR, Lee SA, Lee H, Lee G, Jung BH, Park H, Kim GH, Kim D, Cho G, Kim CH, Ly DD, Park KS, Lee SH
Cell death and differentiation 2022 Mar;29(3):540-555
Cell death and differentiation 2022 Mar;29(3):540-555
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J
EMBO reports 2022 Feb 3;23(3):e53602
EMBO reports 2022 Feb 3;23(3):e53602
Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition.
Liu Y, Gong Z, Zhou J, Yan J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21189
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21189
Lin28A promotes IRF6-regulated aerobic glycolysis in glioma cells by stabilizing SNHG14.
Lu J, Liu X, Zheng J, Song J, Liu Y, Ruan X, Shen S, Shao L, Yang C, Wang D, Cai H, Cao S, Xue Y
Cell death & disease 2020 Jun 11;11(6):447
Cell death & disease 2020 Jun 11;11(6):447
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A.
He Q, Yang S, Gu X, Li M, Wang C, Wei F
Cell death & disease 2018 May 1;9(5):455
Cell death & disease 2018 May 1;9(5):455
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, Rossi S, Pinton S, D'Ambrosio G, Sessa F, Hall J, Catapano CV, Carbone GM
Cancer research 2016 Jun 15;76(12):3629-43
Cancer research 2016 Jun 15;76(12):3629-43
Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts.
Ali N, Allam H, May R, Sureban SM, Bronze MS, Bader T, Umar S, Anant S, Houchen CW
Journal of virology 2011 Dec;85(23):12292-303
Journal of virology 2011 Dec;85(23):12292-303
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 16177-1-AP(Lin28A-specific antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human small intestine using 16177-1-AP(Lin28A-specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Lin28A-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Lin28A-specific. This antibody recognizes human, mouse, rat antigen. The Lin28A-specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
