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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Product number
- HPA040825 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA040825, RRID:AB_10960426
- Product name
- Anti-IP6K1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human IP6K1, Gene description: inositol hexakisphosphate kinase 1, Alternative Gene Names: IHPK1, KIAA0263, Validated applications: ICC, WB, Uniprot ID: Q92551, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Interaction with IP6K1 supports pyrophosphorylation of substrate proteins by the inositol pyrophosphate 5-InsP7
Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system
Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening
IP6K2 predicts favorable clinical outcome of primary breast cancer
InsP7is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export
Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1
Protein kinase- and lipase inhibitors of inositide metabolism deplete IP7 indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity
Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice
Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels
Inositol Pyrophosphate Synthesis by Inositol Hexakisphosphate Kinase 1 Is Required for Homologous Recombination Repair
Hamid A, Ladke J, Shah A, Ganguli S, Pal M, Singh A, Bhandari R
Bioscience Reports 2024;44(10)
Bioscience Reports 2024;44(10)
Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system
Ito M, Fujii N, Kohara S, Hori S, Tanaka M, Wittwer C, Kikuchi K, Iijima T, Kakimoto Y, Hirabayashi K, Kurotaki D, Jessen H, Saiardi A, Nagata E
Journal of Biological Chemistry 2023;299(3):102928
Journal of Biological Chemistry 2023;299(3):102928
Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening
Liao G, Ye W, Heitmann T, Ernst G, DePasquale M, Xu L, Wormald M, Hu X, Ferrer M, Harmel R, Fiedler D, Barrow J, Wei H
ACS Pharmacology & Translational Science 2021;4(2):780-789
ACS Pharmacology & Translational Science 2021;4(2):780-789
IP6K2 predicts favorable clinical outcome of primary breast cancer
Sandström J, Balian A, Lockowandt R, Fornander T, Nordenskjöld B, Lindström L, Pérez‑tenorio G, Stål O
Molecular and Clinical Oncology 2021;14(5)
Molecular and Clinical Oncology 2021;14(5)
InsP7is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
Sahu S, Wang Z, Jiao X, Gu C, Jork N, Wittwer C, Li X, Hostachy S, Fiedler D, Wang H, Jessen H, Kiledjian M, Shears S
Proceedings of the National Academy of Sciences 2020;117(32):19245-19253
Proceedings of the National Academy of Sciences 2020;117(32):19245-19253
The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export
Wilson M, Jessen H, Saiardi A
Journal of Biological Chemistry 2019;294(30):11597-11608
Journal of Biological Chemistry 2019;294(30):11597-11608
Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1
Fu C, Rojas T, Chin A, Cheng W, Bernstein I, Albacarys L, Wright W, Snyder S
Scientific Reports 2018;8(1)
Scientific Reports 2018;8(1)
Protein kinase- and lipase inhibitors of inositide metabolism deplete IP7 indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity
Rajasekaran S, Illies C, Shears S, Wang H, Ayala T, Martins J, Daré E, Berggren P, Barker C
Cellular Signalling 2018;42
Cellular Signalling 2018;42
Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice
Jadav R, Kumar D, Buwa N, Ganguli S, Thampatty S, Balasubramanian N, Bhandari R
Cellular Signalling 2016;28(8):1124-1136
Cellular Signalling 2016;28(8):1124-1136
Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels
Cotterill S, Gu C, Wilson M, Jessen H, Saiardi A, Shears S
PLOS ONE 2016;11(10):e0165286
PLOS ONE 2016;11(10):e0165286
Inositol Pyrophosphate Synthesis by Inositol Hexakisphosphate Kinase 1 Is Required for Homologous Recombination Repair
Jadav R, Chanduri M, Sengupta S, Bhandari R
Journal of Biological Chemistry 2013;288(5):3312-3321
Journal of Biological Chemistry 2013;288(5):3312-3321
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