Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- HPA057285 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA057285, RRID:AB_2683398
- Product name
- Anti-GINS2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human GINS2, Gene description: GINS complex subunit 2 (Psf2 homolog), Alternative Gene Names: Pfs2, PSF2, Validated applications: WB, IHC, ICC, Uniprot ID: Q9Y248, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.5 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references In silico protein interaction screening uncovers DONSON’s role in replication initiation
Mining the prognostic significance of the GINS2 gene in human breast cancer using bioinformatics analysis
Induced expression of GINS complex is an essential step for reactivation of quiescent stem-like tumor cells within the peri-necrotic niche in human glioblastoma
GINS2 regulates cell proliferation and apoptosis in human epithelial ovarian cancer
GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer
Lim Y, Tamayo-Orrego L, Schmid E, Tarnauskaite Z, Kochenova O, Gruar R, Muramatsu S, Lynch L, Schlie A, Carroll P, Chistol G, Reijns M, Kanemaki M, Jackson A, Walter J
Science 2023;381(6664)
Science 2023;381(6664)
Mining the prognostic significance of the GINS2 gene in human breast cancer using bioinformatics analysis
Yu S, Zhu L, Xie P, Jiang S, Wang K, Liu Y, He J, Ren Y
Oncology Letters 2020;20(2):1300-1310
Oncology Letters 2020;20(2):1300-1310
Induced expression of GINS complex is an essential step for reactivation of quiescent stem-like tumor cells within the peri-necrotic niche in human glioblastoma
Kimura T, Cui D, Kawano H, Yoshitomi-Sakamoto C, Takakura N, Ikeda E
Journal of Cancer Research and Clinical Oncology 2018;145(2):363-371
Journal of Cancer Research and Clinical Oncology 2018;145(2):363-371
GINS2 regulates cell proliferation and apoptosis in human epithelial ovarian cancer
Yan T, Liang W, Jiang E, Ye A, Wu Q, Xi M
Oncology Letters 2018
Oncology Letters 2018
GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer
Ouyang F, Liu J, Xia M, Lin C, Wu X, Ye L, Song L, Li J, Wang J, Guo P, He M
Oncology Reports 2017;37(5):2652-2662
Oncology Reports 2017;37(5):2652-2662
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in MCF-7 cells transfected with control siRNA, target specific siRNA probe #1, using Anti-GINS2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
- Sample type
- Human