Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16247-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16247-1-AP, RRID:AB_2111895
- Product name
- PSF2 antibody
- Antibody type
- Polyclonal
- Description
- PSF2 antibody (Cat. #16247-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas.
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function.
Identification of GINS2 prognostic potential and involvement in immune cell infiltration in hepatocellular carcinoma.
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia.
Increased replication origin firing links replication stress to whole chromosomal instability in human cancer.
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components.
Embryonic expression of GINS members in the development of the mammalian nervous system.
Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality.
TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin.
Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction.
A role for USP7 in DNA replication.
He H, Liang L, Jiang S, Liu Y, Huang J, Sun X, Li Y, Jiang Y, Cong L
Cell death & disease 2024 Mar 11;15(3):205
Cell death & disease 2024 Mar 11;15(3):205
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Xu X, Chang CW, Li M, Omabe K, Le N, Chen YH, Liang F, Liu Y
Nature communications 2023 Mar 4;14(1):1233
Nature communications 2023 Mar 4;14(1):1233
Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function.
Xiang S, Luo X, Welch D, Reed DR, Alexandrow MG
Research square 2023 Aug 11;
Research square 2023 Aug 11;
Identification of GINS2 prognostic potential and involvement in immune cell infiltration in hepatocellular carcinoma.
Li Z, Song G, Guo D, Zhou Z, Qiu C, Xiao C, Wang X, Wang Y
Journal of Cancer 2022;13(2):610-622
Journal of Cancer 2022;13(2):610-622
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia.
Conte MI, Poli MC, Taglialatela A, Leuzzi G, Chinn IK, Salinas SA, Rey-Jurado E, Olivares N, Veramendi-Espinoza L, Ciccia A, Lupski JR, Aldave Becerra JC, Mace EM, Orange JS
JCI insight 2022 Nov 8;7(21)
JCI insight 2022 Nov 8;7(21)
Increased replication origin firing links replication stress to whole chromosomal instability in human cancer.
Böhly N, Schmidt AK, Zhang X, Slusarenko BO, Hennecke M, Kschischo M, Bastians H
Cell reports 2022 Dec 13;41(11):111836
Cell reports 2022 Dec 13;41(11):111836
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components.
Fan Y, Köberlin MS, Ratnayeke N, Liu C, Deshpande M, Gerhardt J, Meyer T
The Journal of cell biology 2021 Aug 2;220(8)
The Journal of cell biology 2021 Aug 2;220(8)
Embryonic expression of GINS members in the development of the mammalian nervous system.
Jia W, Hsieh HY, Kidoya H, Takakura N
Neurochemistry international 2019 Oct;129:104465
Neurochemistry international 2019 Oct;129:104465
Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality.
Szmyd R, Niska-Blakie J, Diril MK, Renck Nunes P, Tzelepis K, Lacroix A, van Hul N, Deng LW, Matos J, Dreesen O, Bisteau X, Kaldis P
Oncogene 2019 Feb;38(7):998-1018
Oncogene 2019 Feb;38(7):998-1018
TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin.
Xu X, Wang JT, Li M, Liu Y
The Journal of biological chemistry 2016 Oct 21;291(43):22544-22558
The Journal of biological chemistry 2016 Oct 21;291(43):22544-22558
Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction.
Wang JT, Xu X, Alontaga AY, Chen Y, Liu Y
Cell reports 2014 May 8;7(3):848-58
Cell reports 2014 May 8;7(3):848-58
A role for USP7 in DNA replication.
Jagannathan M, Nguyen T, Gallo D, Luthra N, Brown GW, Saridakis V, Frappier L
Molecular and cellular biology 2014 Jan;34(1):132-45
Molecular and cellular biology 2014 Jan;34(1):132-45
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PSF2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PSF2. This antibody recognizes human,mouse,rat antigen. The PSF2 antibody has been validated for the following applications: ELISA, WB analysis.