Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10953-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10953-1-AP, RRID:AB_2118482
- Product name
- HMGN2 antibody
- Antibody type
- Polyclonal
- Description
- HMGN2 antibody (Cat. #10953-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis.
Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells.
Antitumor effects of STING agonists on nervous system tumors via tumor-intrinsic STING-STAT1-mediated HMGN2 expression.
Inhibition of HMGN2 SUMOylation ameliorates atherosclerosis by activating PAX5 expression to induce macrophage M2 polarization.
A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation.
Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance.
DIA-based quantitative proteomic analysis of porcine endometrium in the peri-implantation phase.
HMGN2, a new anti-tumor effector molecule of CD8⁺ T cells.
Han W, Chen H, Cui B, Chen J, Zhang P, Feng Y
Molecular medicine reports 2026 Mar;33(3)
Molecular medicine reports 2026 Mar;33(3)
Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells.
Feng H, Li Z, Zhang H, Zheng Y, Xu B, Zhang Y, Zou L, Wu L
Nucleic acids research 2026 Feb 5;54(4)
Nucleic acids research 2026 Feb 5;54(4)
Antitumor effects of STING agonists on nervous system tumors via tumor-intrinsic STING-STAT1-mediated HMGN2 expression.
Lv Z, Wang T, Fan R, Ming Q, Liu J, Jia Y, Zhang Y, Chen M, Chen W, Jiang Z, Han W, Mei Q
Cancer biology & medicine 2026 Feb 16;23(1):133-53
Cancer biology & medicine 2026 Feb 16;23(1):133-53
Inhibition of HMGN2 SUMOylation ameliorates atherosclerosis by activating PAX5 expression to induce macrophage M2 polarization.
Wang X, Wu P, Shen Y, Xu S, Wan Q, Yang Y
Experimental cell research 2025 Aug 15;451(2):114709
Experimental cell research 2025 Aug 15;451(2):114709
A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation.
Sin YC, Park M, Griffin TJ, Yong J, Chen Y
Chemical science 2024 Oct 8;15(44):18395-404
Chemical science 2024 Oct 8;15(44):18395-404
Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance.
Xu M, Li F, Xu X, Hu N, Miao J, Zhao Y, Ji S, Wang Y, Wang L
Ecotoxicology and environmental safety 2024 Feb;271:115989
Ecotoxicology and environmental safety 2024 Feb;271:115989
DIA-based quantitative proteomic analysis of porcine endometrium in the peri-implantation phase.
Zhou C, Wang Y, He S, Lin S, Cheng J, Hu Q, Meng F, Gu T, Cai G, Li Z, Wu Z, Hong L
Journal of proteomics 2024 Feb 20;293:105065
Journal of proteomics 2024 Feb 20;293:105065
HMGN2, a new anti-tumor effector molecule of CD8⁺ T cells.
Su L, Hu A, Luo Y, Zhou W, Zhang P, Feng Y
Molecular cancer 2014 Jul 25;13:178
Molecular cancer 2014 Jul 25;13:178
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10953-1-AP(HMGN2 antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The HMGN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HMGN2. This antibody recognizes human antigen. The HMGN2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.