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LearnNBP2-34603AF488
antibody from Novus Biologicals
Targeting: ANO1
DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A
Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-34603AF488 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal DOG1/TMEM16A Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
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