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- References [14]
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- Immunohistochemistry [2]
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- Product number
- 12652-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12652-1-AP, RRID:AB_2722560
- Product name
- TMEM16A/DOG1 antibody
- Antibody type
- Polyclonal
- Description
- TMEM16A/DOG1 antibody (Cat. #12652-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ano1 Antisense Therapy Improves Enamel Properties in Molars but not Amelogenesis in a Murine Model of Cystic Fibrosis.
Exposure to high ambient temperature during pre-implantation impairs embryo transport and development in the oviduct: Potential association with ANO1 downregulation.
WTAP-mediated m(6)A methylation of circRNA_404908 promotes esophageal squamous cell carcinoma progression.
Microtubule-dependent regulation of TMEM16A-mediated Ca(2+)-activated Cl(-) currents in vascular smooth muscle cells.
Integrated proteogenomic characterization of ampullary adenocarcinoma.
TMEM16A inhibits renal tubulointerstitial fibrosis via Wnt/β-catenin signaling during hypertension nephropathy.
Pt(iv) derivatives of cisplatin and oxaliplatin bearing an EMT-related TMEM16A/COX-2-selective dual inhibitor against colorectal cancer cells HCT116.
Primary extra-gastrointestinal stromal tumor of retroperitoneum: Clinicopathologic characteristics and prognosis of six cases.
ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis.
Calcium-activated chloride channel is involved in the onset of diarrhea triggered by EGFR tyrosine kinase inhibitor treatment in rats.
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
Dual role of Ca(2+)-activated Cl(-) channel transmembrane member 16A in lipopolysaccharide-induced intestinal epithelial barrier dysfunction in vitro.
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
Anoctamin-1 in the juvenile rat urinary bladder.
Nedjar D, Bossche AV, Mitri C, Nguyen TN, Hermans F, Torrens C, Roubier N, Vennat E, Montero D, Slimani L, Marotte H, Chaussain C, Tabary O, Tilotta F
Calcified tissue international 2026 Apr 27;117(1)
Calcified tissue international 2026 Apr 27;117(1)
Exposure to high ambient temperature during pre-implantation impairs embryo transport and development in the oviduct: Potential association with ANO1 downregulation.
Zhang HC, Wang RC, Zhu SY, Wang EY, Huang YF, Cao RF, Li HT, Jiang ZL
Journal of thermal biology 2026 Apr 18;139:104461
Journal of thermal biology 2026 Apr 18;139:104461
WTAP-mediated m(6)A methylation of circRNA_404908 promotes esophageal squamous cell carcinoma progression.
Pan Y, Yang H, Zhang J, Zhang R, Yang M, Chen Q, Bie J, Liu K, Song G
The Journal of biological chemistry 2025 Sep;301(9):110512
The Journal of biological chemistry 2025 Sep;301(9):110512
Microtubule-dependent regulation of TMEM16A-mediated Ca(2+)-activated Cl(-) currents in vascular smooth muscle cells.
Hemmi R, Suzukawa A, Fujiwara M, Kondo R, Suzuki Y, Yamamura A, Yamamura H
Journal of pharmacological sciences 2025 Nov;159(3):202-207
Journal of pharmacological sciences 2025 Nov;159(3):202-207
Integrated proteogenomic characterization of ampullary adenocarcinoma.
Zhang Q, Xu X, Jiang D, Wang Y, Wang H, Zhu J, Tang S, Wang R, Zhao S, Li K, Feng J, Xiang H, Yao Z, Xu N, Fang R, Guo W, Liu Y, Hou Y, Ding C
Cell discovery 2025 Jan 7;11(1):2
Cell discovery 2025 Jan 7;11(1):2
TMEM16A inhibits renal tubulointerstitial fibrosis via Wnt/β-catenin signaling during hypertension nephropathy.
Wang F, Zhang Y, Gao M, Zeng X
Cellular signalling 2024 May;117:111088
Cellular signalling 2024 May;117:111088
Pt(iv) derivatives of cisplatin and oxaliplatin bearing an EMT-related TMEM16A/COX-2-selective dual inhibitor against colorectal cancer cells HCT116.
Ma ZY, Ding XJ, Zhu ZZ, Chen Q, Wang DB, Qiao X, Xu JY
RSC medicinal chemistry 2024 Aug 1;15(9):3239-47
RSC medicinal chemistry 2024 Aug 1;15(9):3239-47
Primary extra-gastrointestinal stromal tumor of retroperitoneum: Clinicopathologic characteristics and prognosis of six cases.
Lin J, Liao W, Wang J, Li W, Tang X, Li H, Yi X, Lu X, Chen Z, Zhu B, Feng X, Diao D
Frontiers in oncology 2023;13:1033598
Frontiers in oncology 2023;13:1033598
ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis.
Deng CM, Zhang GG, Liu QW, Xu JJ, Liu ZC, Yang J, Xu TY, Li ZG, Zhang F, Li B
Cancer research 2023 Jun 2;83(11):1851-1865
Cancer research 2023 Jun 2;83(11):1851-1865
Calcium-activated chloride channel is involved in the onset of diarrhea triggered by EGFR tyrosine kinase inhibitor treatment in rats.
Harada Y, Sekine H, Kubota K, Sadatomi D, Iizuka S, Fujitsuka N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111860
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Sep;141:111860
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
Hong Y, Ren X, Liu W, Sun K, Chen B, Liu B, Yu X, Chen Q, Qian Q, Xie X, Jiang C
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447
Dual role of Ca(2+)-activated Cl(-) channel transmembrane member 16A in lipopolysaccharide-induced intestinal epithelial barrier dysfunction in vitro.
Sui J, Zhang C, Fang X, Wang J, Li Y, Wang J, Wang L, Dong J, Zhou Z, Li C, Chen J, Ma T, Chen D
Cell death & disease 2020 May 29;11(5):404
Cell death & disease 2020 May 29;11(5):404
Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.
Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP
eLife 2018 Feb 2;7
eLife 2018 Feb 2;7
Anoctamin-1 in the juvenile rat urinary bladder.
Bijos DA, Drake MJ, Vahabi B
PloS one 2014;9(9):e106190
PloS one 2014;9(9):e106190
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 12652-1-AP(ANO1,DOG1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TMEM16A/DOG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TMEM16A/DOG1. This antibody recognizes human,mouse,rat antigen. The TMEM16A/DOG1 antibody has been validated for the following applications: ELISA, IHC analysis.
