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- References [2099]
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- Product number
- 14600-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14600-1-AP, RRID:AB_2137737
- Product name
- LC3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LC3 antibody (Cat. #14600-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Environmental Fluoride Compromises Male Fertility: Differentially Modulated miR-34a-5p Targets REST to Regulate Autophagy in Testicular Somatic Cells.
A Novel Autophagy Inhibitor p-Hydroxylcinnamaldehyde Suppresses Esophageal Squamous Cell Carcinoma by Targeting LDHA Phosphorylation-Mediated Metabolic Reprogramming.
p62 limits Salmonella Typhimurium in macrophages through its role in cell signalling.
Monitoring Autophagosome Biogenesis and Degradation in Mammalian Cells Using LC3B Blotting.
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
SIRT6-Mediated Regulation of TFAM: A Central Mechanism Connecting Nuclear and Mitochondrial Transcriptional Processes and Mitophagy.
ATG7 vs. ATG5: Distinct autophagy pathways shaping TGF-β signaling and endothelial function.
Aspergillus fumigatus Gliotoxin Inhibits LC3-Associated Phagocytosis in Macrophages in a Calcium-Dependent Manner.
Quercetin regulates autophagy and attenuates airway inflammation in a murine model of asthma: association with PI3K/Akt/mTOR signaling pathway modulation.
Arsenic trioxide-induced acute kidney injury: OPA1- and Drp1-mediated mitochondrial dynamics imbalance, PINK1/Parkin-dependent mitophagy, and Chuanhuang Fang III.
Nanosized silicon nitride promotes vascularized osteogenesis through regulating the endothelial adherens junctions via the FRMD6/VE-cadherin pathway.
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
Quercetin attenuates tendon stem/progenitor cell senescence and promotes aged tendon repair via AKT/NF-κB/NLRP3-mediated mitophagy activation.
Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
Astragalus membranaceus Polysaccharides Attenuate Osteoarthritis in Human Primary Chondrocytes and in Animal Model: Mechanism Study Using RNA-Seq and Network Pharmacology.
Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.
Maresin 1 activates autophagy through SIRT1/PPAR-γ signaling to mitigate high glucose-induced pyroptosis in human retinal pigment epithelial cells.
Schisandrin B enhances autophagy and random flaps survival through the PPARG-mediated PI3K/AKT/mTOR signaling pathway.
Detoxification of T-2 toxin in human chondrocytes due to its hydroxylation by carboxylesterases and arylacetamide deacetylase in the liver.
vtRNA1-1/p62 regulates macrophages autophagy in ankylosing spondylitis.
High-fat diet perturbs hepatic lipid metabolism and impairs colonic autophagy to exacerbate experimental colitis.
Ginsenoside Rg1 mitigates sepsis-associated acute respiratory distress syndrome by promoting autophagy through the Prdx1-PTEN/PI3K/AKT pathway.
PGC-1α exacerbates apoptosis to induce HIF-1α/BNIP3 mediated mitophagy in heart failure.
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.
Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro.
Stattic engineering M2 macrophage-derived exosomes mediate autophagy and immune reprogramming for secondary hyperparathyroidism.
Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids.
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
BNIP3L-Mediated Mitophagy Inhibits Cadmium-Induced Apoptosis in the Rat Cerebral Cortex.
Rapamycin Reduces Amyloid-β Plaques and Improves Behavioral Performance in a Sex-Dependent Manner in Mouse Models of Amyloidosis.
Trehalose Alleviates the Advancement of Temporomandibular Joint Osteoarthritis via Regulating the AMPK/ULK1 Autophagy Pathway.
ZNF16 inhibits PEDV replication through autophagy-mediated degradation of S1 protein.
Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.
Gentiana szechenyii Kanitz Compounds Regulate Lipopolysaccharide-Induced Inflammation and Mitochondrial Autophagy Via the Toll-Like Receptor 4-Nuclear Factor Kappa B Pathway.
Proximity labelling identifies proteins associated with HSV-2 pUL21 at early and late times after infection.
Astaxanthin improves assisted reproductive outcomes in patients with poor ovarian response by alleviating oxidative stress and regulating granulosa cell mitochondrial function.
Cyclophilin A stabilizes the capsid protein p72 to facilitate African swine fever virus replication.
Spermine Ameliorates DSS-Induced Ulcerative Colitis in Mice by Improving Mitophagy and Intestinal Microbiota.
Lactiplantibacillus pentosus JWN01 and Lactiplantibacillus plantarum JWN02 attenuate renal fibrosis and pathological autophagy in hyperuricemic nephropathy via gut-kidney axis.
The segmented flavivirus ALSV-encoded nucleoprotein VP2 inhibits type I interferon production by targeting RIG-I.
Resveratrol Attenuates Liver Inflammation in Non-Alcoholic Fatty Liver Disease by Activating PINK1-Mediated Mitophagy.
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
A germline-specific vesicular structure licenses mRNA activation during spermiogenesis and is hijacked in gastric cancer.
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis.
IL-22/IL-22R signaling attenuates mitochondrial damage in PCOS by modulating granulosa cell lipid metabolism through ETS1.
Astragalus Polysaccharide Alleviated Septic Associated Acute Kidney Injury Through Dual Mechanisms of RIPK1-Dependent Necroptosis and Autophagy in Macrophage.
Overexpression of As3mt Attenuates Sodium Arsenite Induced Ferritinophagy and Hepatic Lipid Accumulation in Mice.
ITPR1 mediates the PI3K/AKT/mTOR pathway to regulate cellular autophagy, affecting lipopolysaccharide-induced pediatric inflammatory bowel disease.
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
O-GlcNAcylation of YAP1 promotes lung transplant ischemia-reperfusion injury via binding to HIF1α transcription factor and activating autophagy and mitophagy.
Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury.
Fasting-induced physiological remodeling alleviated fatty liver in laying hens through regulating hepatic lipid metabolism.
Ubiquitin C-terminal hydrolase L3 promotes liver cancer cell proliferation by modulating the AMP-activated protein kinase signaling pathway.
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome.
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.
Qiang-Xin 1 formula improves cardiac function and alleviates myocardial injury in lipopolysaccharide-induced septic mice by activating calcium/calmodulin-dependent protein kinase I-mediated mitophagy.
Increased Glycogenin-Exposed Residual Glycogen in Lysosomes Is the Early Pathological Finding in Asymptomatic Pompe Disease.
Membrane-camouflaged nanoparticle alleviates intervertebral disc degeneration via oxidative stress suppression and autophagy activation.
Helicobacter pylori-secreted outer membrane vesicles induce bone loss and accelerate osteoporosis pathogenesis in mice by regulating gut microbiota and autophagy.
Extracellular vesicle-mediated transcellular mitophagy as a modulatory target for moderate hyperoxia-induced alveolar developmental arrest in bronchopulmonary dysplasia.
Urban particulate matter induces NLRP3/NLRP6 inflammasomes, autophagy, senescence and fibrotic responses by increasing CSF2 signaling in kidney cells.
Atractylenolide I ameliorates acute-on-chronic liver failure (ACLF) by promoting autophagy and preserving mitochondrial function through mTOR inhibition.
TREM2 activation suppresses central sensitisation by promoting autophagy in a chronic migraine model with recurrent nitroglycerin stimulation in mice.
Usenamine a potentiates anti-CRC activity of sorafenib by inducing autophagy and inhibiting YAP pathway through targeting SOD2.
SIRT1 agonist SRT1720 alleviates cerebral ischemia-reperfusion injury by inhibiting lactate-mediated SOD2 Lactylation and suppressing NCOA4-mediated ferritinophagy-ferroptosis.
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
TRIM27 promotes microglial M2 polarization and neuroprotection via TBK1-dependent autophagy in cerebral ischemia-reperfusion injury.
A potent icaritin derivative ameliorates Parkinson's disease via GPER-mediated mitophagy restoration and dopaminergic neuroprotection.
Polystyrene microplastics disrupt the blood-testis barrier via CEBPB-driven lysosomal autophagy and induce ferroptosis-like injury in human sperm, compromising embryo development.
A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.
GPX3 activates autophagy to protect cochlear spiral ganglion neurons from injury in age-related hearing loss.
Autophagy in Cadmium-Induced Hepatic Injury of Rats: Protective Role of Naringenin.
Selaginella Tamariscina extract reduces UVA-induced skin photodamage via regulating apoptosis and autophagy by AKT phosphorylation.
Astrocytes differentiated from patient iPSCs model the rare leukodystrophy MLC and uncover disease-linked maturation defects and Kir4.1 channel dysfunction.
Sesamin exerts protective effects against diquat-induced acute kidney injury by inhibiting oxidative stress, apoptosis and autophagy: A key role for the SIRT5/FOXO3a signaling pathway.
Hydrogen sulfide promotes proliferation and regeneration of human cerebral microvascular endothelial cells via the sonic hedgehog signaling pathway.
FABP4-mediated lipid droplet accumulation drives epithelial-mesenchymal transition and aggravates alveolar epithelial barrier disruption.
Ginsenoside Rc inhibits diabetic cardiomyopathy by reducing lipotoxicity through the adiponectin and autophagy pathways.
Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux.
Epicatechin Gallate Ameliorates UVB-Induced Photoaging by Inhibiting p38α-Mediated Autophagy and Oxidative Stress.
Decoding the MYC locus reveals a druggable ultraconserved RNA element.
Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Zalcitabine induces ferroptosis in multiple myeloma through the TFAM-cGAS-STING-SLC7A11 axis.
Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migration.
CDC25C downregulation suppresses HCC growth via mitochondrial stress-induced autophagy and apoptosis.
Thonningianin A derived from Penthorum chinense Pursh alleviates cerebral ischemia/reperfusion-mediated apoptosis and pyroptosis through the activation of PINK1/Parkin-dependent mitophagy.
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
The protective effect of asperuloside on liver injury: Insights from metabolomics and the mTOR-mediated autophagy perspective.
tRNA m(2)G methyltransferase complex THUMPD3-TRMT112 promotes pancreatic cancer progression and autophagy via modulating TFEB translation.
Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy.
Butyrate-Modified Hyaluronic Acid Ameliorates MPTP-Induced Parkinson's Disease via Modulating PINK1/Parkin-Involved Mitophagy and Intestinal Flora.
Xi Huang Pill exerts anti-triple-negative breast cancer effects by modulating gut microbiota, regulating glycerophospholipid metabolism, and promoting autophagy homeostasis.
Integrated multi-omics and machine learning elucidate the pathogenic role of mitophagy in osteoarthritis and identify novel therapeutic strategies.
Allergen-induced dendritic cell autophagy drives immune imbalance in asthma.
Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy.
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism.
Neuroprotective effects of dexmedetomidine in spinal cord injury via modulating PERK/ATF4 pathway.
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Picornavirus VP2 protein suppresses innate immunity through selective autophagic degradation of IKBKE/IKKε.
L-tetrahydropalmatine attenuates methamphetamine-induced pulmonary vascular remodeling via CaSR-BMP2/mTOR signaling.
Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer.
Cannabidiol alleviates methamphetamine-induced autophagy and oxidative stress by suppressing sigma 1 receptor expression.
NSUN3-mediated m5C modification of FABP5 regulates lipid droplets through autophagy to alleviate osteoarthritis progression.
Ginsenoside 20(S)-Rg3 alleviates cage stress induced liver injury in laying ducks.
SREBF2 enhances lipid metabolism and represses anti-tumor immune responses in cervical cancer by increasing ACAT2.
FRZB regulates the osteogenic differentiation of periodontal ligament stem cells in an inflammatory microenvironment through Wnt5a-mitochondrial axis.
Lipophagy Dynamics in Hyperlipidemia Model ICR Mice Across Different High-Fat-Diet Feeding Durations.
Knockout of the C4BPA Gene Promotes Mitophagy via Activation of the Pink1/Parkin Pathway and Alleviates the Inflammatory Response by Inhibiting the NF-κB Signalling Pathway in Bovine Mammary Epithelial Cells.
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPK-MTOR-autophagy pathway in macrophage.
Bidens biternata (Lour.) Merr. & Sherff improves liver lipid metabolism disorders in type 2 diabetic mice by activating mitophagy.
CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy.
Oncolytic adenovirus type 11-induced ferroptosis of esophageal squamous cell carcinoma cells involves in mitochondrial impairment and the mTOR pathway.
KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression.
MUL1 suppresses cervical cancer progression by targeting FUNDC1 for ubiquitination and inhibiting DRP1-dependent mitophagy.
Therapeutic potential of magnesium diboride nanosheets in PAH-associated right heart failure: Integrated multi-omics analysis reveals ferroptosis suppression via LC3/ATG5/NCOA4/FTH1 pathway.
Lactiplantibacillus plantarum GUANKE ameliorates influenza a virus-induced inflammation and lung barrier dysfunction through enhancing mitophagy and improving oxidative phosphorylation.
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.
Staphylococcus aureus escapes endosomes and autophagosomes via α-hemolysin.
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
ATP6V0A1 protects dopaminergic neurons via the autophagy-lysosomal pathway in Parkinson's disease.
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
Renal-targeted tFNA-TPP nanoagonist treats acute kidney injury by amplifying mitophagy.
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
CCT7 Regulates TRAF6-Mediated Autophagy to Promote Posttraumatic Joint Contracture.
MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.
Hydrogen-Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy.
Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells.
Extracorporeal Shock Wave Therapy Promotes Peripheral Nerve Regeneration Through ERK1/2-Mediated Autophagy.
Celastrol triggers CAV-1-mediated mitochondrion cholesterol metabolism and mitophagy to suppress liver cancer.
Diosmetin alleviates hyperuricemic nephropathy by activating the BNIP3/Nrf2/GPX4 pathway to inhibit ferroptosis of renal tubular epithelial cells induced by monosodium urate crystals.
Targeting the GPX4-FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis-Associated Lung Injury.
IRF4 Enhances Radiosensitivity of Cervical Cancer by Inhibiting the PI3K/Akt/mTOR Pathway to Regulate Autophagy.
The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency.
Targeting Fgr-STAT3 Mediated Autophagy Inhibition in the Spinal Cord Alleviates Neuropathic Pain in Rats.
African swine fever virus hijacks lipolysis induced by chaperone-mediated autophagy to upregulate fatty acid β-oxidation and promote viral replication.
Evolutionarily conserved signaling intermediate in Toll pathways facilitates exercise-induced amelioration of skeletal muscle atrophy by maintaining mitochondrial quality control in middle-aged mice.
A tumor-derived mitochondrial tsRNA drives vascular invasion of lung adenocarcinoma by promoting ribosomal assembly in endothelial cells.
Stabilizing MARCH7 as a ferro-guardian against ferroptosis.
Overexpression of miR-7641 activates ox-LDL-induced autophagy in macrophages by regulating USP7.
Pestiviruses utilize pyrimidine metabolism to regulate mitophagy for viral replication.
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Dual-Shell Chitosan/Ferritin Nanocages Enhance the Stability, Intestinal Transport, and Antiviral Activity of EGCG against HBV.
Xuming tongmai decoction modulates astrocyte polarization and mitophagy via the PINK1/Parkin pathway in a rat model of acute ischemic stroke.
Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway.
Sustained high-fat diet intake differentially regulates hepatic lipophagy and metabolic adaptation after bariatric surgery in obese rats.
Saikosaponin D Alleviates Liver Ischemia-Reperfusion Injury by Inhibiting Mitophagy-Associated Ferroptosis via the STAT3/PINK1 Pathway.
African swine fever virus pE199L, as a mitophagy receptor, suppresses antiviral innate immunity to promote viral replication.
Suppression of Nr1d1/Bnip3-dependent mitophagy by notch signaling aggravates inflammatory response in RSV-infected mice lungs.
USP2 Attenuates Spermatogenic Cell Apoptosis Via PINK1/Parkin-Dependent Mitophagy in Varicocoele: A Functional Study.
Upstream Stimulatory Factor 2 Protects Cardiomyocytes by Regulating Mitochondrial Homeostasis.
Perfluorooctane sulfonate induces hepatotoxicity through promoting inflammation, cell death and autophagy in a rat model.
Mitochondrial autophagy inhibits nucleotide-binding oligomerization domain-like receptor protein 3-mediated pyroptosis and alleviates endothelial cell injury in pregnancy-induced hypertension.
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
DARS2 Promotes Bladder Cancer Progression by Enhancing PINK1-Mediated Mitophagy.
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice.
lncRNA NKILA Promotes Warburg Effect and Immune Escape in Intrahepatic Cholangiocarcinoma by Regulating the MTX1/TOMM40 Axis.
The Active Ingredients and Potential Mechanism of Qijia Rougan Decoction in Autophagy and Hepatic Stellate Cell Activation Modulation in Liver Fibrogenesis.
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling.
Identification and validation of key autophagy-related genes in lupus nephritis by bioinformatics and machine learning.
Inhibition of ATG7 promotes orthodontic tooth movement by regulating the RANKL/OPG ratio under compression force.
Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy.
RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells.
Artesunate Mitigates Sepsis-Induced Acute Kidney Injury via Lactate/AMPK/mTOR-Regulated Autophagy Based on Multi-Omics.
Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy.
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Enhancing autophagy mitigates LPS-induced neuroinflammation by inhibiting microglial M1 polarization and neuronophagocytosis.
Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy.
Rapamycin and Chloroquine Modulate Insulin Resistance and Hepatic Steatosis in a High-Fat/High-Cholesterol Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Mouse Model.
Sigma-1 Receptor Rescues Autophagy Through AMPK/mTOR Signaling Pathway in Sepsis-Induced Acute Kidney Injury.
CAPN1 Promotes Pseudomonas aeruginosa-Induced Infection by Interacting with TFEB and Inhibiting Autophagy.
Nurr1 deficiency impairs autophagy-lysosomal function through GBA-dependent transcriptional regulation in Parkinson's disease pathogenesis.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality.
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation.
Targeting mitophagy in diabetic retinopathy: novel insights into SQSTM1/BNIP3L pathway regulated by luteolin.
Bletilla striata polysaccharide induces autophagy through PI3K/AKT signaling pathway to promote the survival of cross-boundary flap in rats.
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Moderate intensity continuous training mitigates hypertension-induced renal fibrosis by inhibiting HIF-1α-mediated autophagy.
Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiments.
αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke.
Splicing factor 3b subunit 4 (SF3b4) is mediated by EP300 and CREBBP to promote colorectal cancer (CRC) proliferation by enhancing autophagy.
Ultrasound-activated erythrocyte membrane-camouflaged Pt (II) layered double hydroxide enhances PD-1 inhibitor efficacy in triple-negative breast cancer through cGAS-STING pathway-mediated immunogenic cell death.
The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinoma.
Neutrophil hitchhiking liposomal drugs for starvation therapy in endometriosis.
GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.
Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.
Overexpression of BNIP3 in renal carcinoma cells can promote apoptosis of renal carcinoma cells through HIF-1α-BNIP3-mediated autophagy.
Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer.
Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.
Sestrin2 Regulates Mitochondrial Function and Autophagy via Nrf2/SIRT3 Signaling to Ameliorate Hypoxia/Reoxygenation-Induced Rat's Cardiomyocyte Injury.
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
ADSC-EVs Activate Autophagy Via the AKT/FOXO1 Pathway to Inhibit Tendon Fibrosis.
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation.
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
TTK promotes mitophagy by regulating ULK1 phosphorylation and pre-mRNA splicing to inhibit mitochondrial apoptosis in bladder cancer.
Phillygenin ameliorates myocardial ischemia-reperfusion injury by inhibiting cuproptosis via the autophagy-lysosome degradation of CTR1.
Resveratrol ameliorates streptozotocin induced renal inflammation and promotes autophagy by mediating the SphK1 pathway via Sirt1 in Wistar rats.
Huotan Jiedu Tongluo Decoction targets Nrf2-mediated macrophage autophagy to inhibit ferroptosis and reduce atherosclerotic lesions.
The antitumor effects of lupenone on colon cancer and its mechanistic insights.
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
Investigating the role of 1,8-Cineole in mitigating ferroptosis in a HFSD/STZ diabetes mellitus type 2-induced model: A GEO data analysis approach.
ARIH1 Promotes Preeclampsia by Inducing MFN2-Dependent Hypoxia-Triggered Mitophagy and Endoplasmic Reticulum Stress in Trophoblasts.
TFAP2A induces cisplatin resistance via BNIP3-mediated mitophagy in non-small cell lung cancer.
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of SAT1 and GPX4 expression.
PINK1 functions in mitophagy and mitochondrial homeostasis during mice oocyte maturation.
Comparison of the therapeutic efficacy of leukocyte-poor and leukocyte-rich platelet-rich plasma in rabbit knee osteoarthritis and the study of autophagy mechanism.
The reduced DLG5 promotes doxorubicin resistance in breast cancer cells MCF-7 through regulating autophagy.
Coordination of autophagosome closure and release by the Alzheimer's disease-associated protein BIN1.
The BPIFA2 - LRP5 axis orchestrates mitochondrial dysfunction to mediate kidney injury in lupus nephritis.
Melatonin attenuates ischemia-reperfusion-induced acute kidney injury by regulating abnormal autophagy and pyroptosis through SIRT1-mediated p53 deacetylation.
Adipose-derived stem cell exosomes promote neurological recovery after subarachnoid hemorrhage via AMPK/mTOR-mediated TFEB activation.
LINC01018 attenuates hepatic lipid accumulation by inducing autophagy via DHX9 pathway in alcohol-associated liver disease.
CPNE5 overexpression inhibits cardiomyocytes apoptosis by promoting the degradation of FAS receptor.
Salidroside Attenuates Cerebral Ischemia-Reperfusion Injury via ERβ/BNIP3-Mediated Mitochondrial Autophagy Activation in a Rat Model.
11β-HSD1 inhibitor alleviates sepsis-induced cardiac dysfunction by regulating macrophage polarization via the AMPK/mTOR autophagy pathway.
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
CUMS stress facilitates hippocampal neural mitophagy through FIS1/MFF-mediated mitochondrial fragmentation.
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
Bim and Mcl-1 coordinate NVP-BEZ235-induced renal cell carcinoma cell apoptosis.
Nitrate-driven maintenance of lipid homeostasis by M2 macrophages alleviates atherosclerosis via downregulation of LOX1 expression and reduction of lipid deposition.
Effect of activated autophagy on an animal model of vestibular migraine-like attacks.
SAMHD1 deficiency disrupts macrophage autophagy-lysosomal homeostasis and promotes inflammation via the mTOR-MITF-CTSD axis in ulcerative colitis.
Oxymatrine attenuates pulmonary fibrosis via APE1‑mediated regulation of the PINK1/Parkin pathway.
Enhancement of photodynamic reaction by chloroquine through apoptosis induction, lipid peroxidation augmentation, and autophagy inhibition using IR-783.
Synthesis and anticancer studies of Ru/Ir arene complexes bearing oleanolic acid in acute promyelocytic leukemia cells.
Maresin1 ameliorates osseointegration in type 2 diabetes mellitus by promoting FAM134B-mediated ER-phagy in osteoblasts.
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Sestrin2 improves intestinal ischemia-reperfusion injury through the TFEB-mediated autophagy/lysosomal pathway.
HMGA2 Attenuates Tendon Stem/Progenitor Cell Senescence Via PI3K/AKT-Mediated Mitophagy Activation and SASP Suppression.
A prognostic model of platinum resistance in osteosarcoma: Key roles of BNIP3, MYC, and ACTA2.
Berberine partially ameliorates cardiolipotoxicity in diabetic cardiomyopathy by modulating SIRT3-mediated lipophagy to remodel lipid droplets homeostasis.
Puerarin enhances the efficacy of carboplatin in oral squamous cell carcinoma via dual targeting.
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
Wogonin modulates macrophage polarization and inflammatory signaling through the LSD1-p65 axis to alleviate osteoarthritis.
Artificial intelligence combined with affinity chromatography discover that 7-Epitaxol promotes autophagy in NSCLC cells by interacting with EGFR: Discovery of novel EGFR antagonist based on DL and CMC.
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.
Yogurt alleviates alcohol-induced hepatocyte pyroptosis and inflammation via autophagy/P62/Nrf2/ROS/NLRP3 pathway.
Plastic tableware use, microplastic accumulation, and sperm quality: from epidemiological evidence to FOXA1/p38 mechanistic insights.
Novel Isolongifolenone-Based Caprolactam Derivatives as Potential Anticancer Agents via the p53/mTOR/Autophagy Pathway.
Uncovering the Regulatory Role of Proteins in EBSS-Induced Autophagy Using RNA-Seq Analysis.
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
Wuhu decoction regulates ROS/AMPK/mTOR pathway-mediated dendritic cells autophagy and pyroptosis for the treatment of respiratory syncytial virus-induced asthma.
Reactive Oxygen Species (ROS) Drive Osteocyte Dysfunction in Diabetic Osteoporosis by Impairing Autophagy and Triggering Apoptosis.
Paeoniflorin inhibits glioblastoma proliferation and promotes autophagy through the AKT/mTOR pathway.
Bisphenol A Disrupts Spermatogenesis via Excessive Mitophagy-Driven Ferroptosis.
Combination of B-AP15 and HSP90 inhibitor tanespimycin induces ROS-mediated cytotoxicity in human lung cancer cells.
Miro1 protects against brain injury after CPR in rats by enhancing the effect of BMSCs on mitochondrial homeostasis.
ITCH regulates Golgi integrity and proteotoxicity in neurodegeneration.
Piezo1 exacerbates psoriasis by promoting macrophage M1 polarization and inhibits autophagy via activating PI3K/AKT signaling pathway.
Lipidomics Revealed the Suppression of 5-PAHSA from Human Milk on Macrophage Foam Cell Formation.
HIF-1α Activates Mitophagy through BNIP3 to Inhibit IPEC-J2 Apoptosis under Heat Stress.
Visual Whole-Process Monitoring Dynamic Phase Separation of Autophagic Lysosomes in Alzheimer's Disease by a Lysosome-Targeted pH-Activated Fluorescence Probe.
Stigmasterol improves diabetic retinopathy by inhibiting VAMP7-mediated autophagy/mitophagy.
DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway.
Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling.
Reversal of neurodevelopmental toxicity induced by combined exposure to the neonicotinoid insecticides acetamiprid and imidacloprid in zebrafish through targeting DRP-1: insights into mitophagy and apoptosis mechanisms.
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
GPR30-mediated the MEK/ERK signaling pathway promotes porcine oocyte maturation and development.
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence.
Inhibition of calcium-sensing receptor by its antagonist protects dopaminergic neurons from MPTP/MPP(+)-induced neurotoxicity via regulating mitochondrial function, autophagy, and apoptosis in vivo and in vitro.
PK11007 Covalently Inhibits Thioredoxin Reductase 1 to Induce Oxidative Stress and Autophagy Impairment in NSCLC Cells.
Yunnan Baiyao regulates Th17/Treg cell homeostasis to inhibit periodontitis through the miR-155-5p/ATG5 pathway.
Vilazodone ameliorates senescence-related Alzheimer's disease like symptoms by targeting Plau to induce autophagy in senescent cells.
Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 6.
TRIM39-mediated deubiquitination upregulates RNF168 to evade autophagy-ferroptosis in triple-negative breast cancer.
Development of an efficient mice model of cancer-associated cardiac cachexia.
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer.
Neuropeptide Y1 receptor antagonist alleviated osteoarthritis by restoring chondrocyte autophagy through PI3K/AKT/mTOR signaling pathway.
Cadmium-mediated autophagy increases ferroptosis of ovarian granulosa cells.
(20S)-protopanaxatriol attenuates Ang II-induced renal injury via PTPN1-mediated AMPK/mTOR signaling pathway.
Autophagic damage in senescent bone marrow mesenchymal stromal cells: Impact on Piezo1 expression during osteoporosis progression.
Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy.
Caulerpa lentillifera extract alleviates the chronic diquat-induced liver oxidative damage in zebrafish (Danio rerio) in association with Nrf2 and AMPK/mTOR signaling pathway.
The V-ATPase a3 subunit deficiency affects osteoarthritis via mTOR-Mediated autophagy levels in subchondral bone.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
S-palmitoylation coordinates the trafficking of ATG9A to mediate autophagy initiation.
SFTSV induces liver ferroptosis through m6A-related ferritinophagy.
NSUN6 Promotes Gastric Cancer Progression by Stabilizing CEBPZ mRNA in a m(5)C-Dependent Manner.
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF-κB signaling activation.
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Traditional wisdom meets modern science: The protective role of sanhuang shu'ai decoction in ulcerative colitis models.
Calcitriol/Vitamin D receptor ameliorates fructose-induced enteritis-hepatitis axis dysregulation in mice.
Untargeted metabolomics reveals the mechanisms of luteolin and exercise combination treatment against cognitive impairments in AD mice through modulating autophagy.
Regulation of melanogenesis via ubiquitin-proteasome system and autophagy by 3,3,5-trimethylcyclohexyl succinate dimethylamide and tranexamic acid.
Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Transaldolase 1 impacts Parkinson's disease pathogenesis via metabolic reprogramming and autophagy-lysosomal pathway.
New perspective on postmortem meat quality changes of Esox Lucius: The role of mitophagy-mediated ferroptosis pathway.
Liraglutide Mitigates Renal Injury in Diabetic Kidney Disease by Suppressing Podocyte Cholesterol Accumulation Through mTOR/VMP1-Regulated Autophagy.
Autophagy-targeted intervention synergized with pegaspargase: an innovative therapeutic paradigm for pancreatic cancer.
Ferroptosis mediated by ferritinophagy is involved in liver injury caused by sepsis.
Bergamot Polyphenols Reduce Hepatic Lipogenesis While Boosting Autophagy and Short-Chain Fatty Acid Production in a Murine "Cafeteria" Model of MASLD.
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Semen Ziziphi Spinosae affects circadian rhythm of the cAMP signaling pathway by BMAL1-clockophagy to improve sleep disorders in depression.
The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.
Hyperoside Promotes Mitochondrial Autophagy Through the miR-361-5p/PI3K/Akt/mTOR Signaling Pathway, Thereby Improving UVB-Induced Photoaging.
5-Aminoimidazole-4-carboxamide-1- β -d-ribofuranoside ameliorates lipotoxicity through enhanced reticulophagy in HepG2 cells.
[Astragaloside IV alleviates D-GAL-induced endothelial cell senescence by promoting mitochondrial autophagy via inhibiting the PINK1/Parkin pathway].
Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.
Ribosome dysregulation and intervention in age-related infertility.
BPP disrupts spermatogenesis via mitochondrial-ER stress-mediated autophagic flux blockade in mice.
The EGR1/miR-199a-3p/mTOR axis: A crucial pathway in the amplification of myocardial damage under intermittent hypoxic conditions.
NCOA4-mediated ferroptosis conducive to EMT inhibition in colorectal cancer cells was achieved through the PI3K/AKT/mTOR pathway.
Neuroglobin-promoted autophagy inhibits the proliferation, migration and invasion of human glioblastoma cells through the EGFR/PI3K/AKT/mTOR signaling pathway.
Gallic Acid Alleviates Cerebral Ischemia-reperfusion Injury in Mice by Mediating Microglial Polarization Through the NLRP3/mTOR Axis.
CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.
Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.
Pioglitazone reduces hepatic α-1 antitrypsin accumulation through autophagy and AMPK activation in α-1 antitrypsin-deficient mice.
Neuromuscular electrical stimulation alleviates stroke-related sarcopenia by promoting satellite cells myogenic differentiation via AMPK-ULK1-Autophagy axis.
6PPD induces apoptosis and autophagy in SH-SY5Y cells via ROS-mediated PI3K/AKT/mTOR pathway: In vitro and in silico approaches.
Daidzein Attenuates Cadmium-Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague-Dawley Rats.
Aerobic exercise improves astrocyte mitochondrial quality and transfer to neurons in a mouse model of Alzheimer's disease.
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.
Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Lactoferrin ameliorates cognitive impairment in D-galactose-induced aging mice by regulating the PI3K/Akt/mTOR signaling pathway and the microbiome-gut-brain axis.
NSUN2-mediated m5C modification of circFAM190B promotes lung cancer progression by inhibiting cellular autophagy.
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
EPIC-1042 alleviates cerebral ischemic/reperfusion injury through TAX1BP1-induced mitophagy.
Methionine is an essential amino acid in doxorubicin-induced cardiotoxicity through modulating mitophagy.
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Deubiquitinase USP13 alleviates doxorubicin-induced cardiotoxicity through promoting the autophagy-mediated degradation of STING.
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade.
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism.
6-shogaol alleviates excessive neuronal autophagy and calcium overload following cerebral ischemia-reperfusion injury by inhibiting the expression of DAPK1.
Rilmenidine attenuates intracerebral hemorrhage by regulating autophagy flux and apoptosis via the HO-1/Fe(2+)/ERK pathway.
Conjugation with the XJB peptide enhanced neuroprotective effect of honokiol via SIRT3 modulation.
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Mitochondrial Genome-Encoded lncND5 Regulates Mitophagy in Hypoxic Pulmonary Artery Smooth Muscle Cell.
Enhanced SIRT1-TFEB Interaction Promotes Lysosome Biogenesis and Autophagy by Reducing TFEB Acetylation: Revealing the Enterotoxicity Disparity of Deoxynivalenol and T-2 Toxin.
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection.
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
RAB18 deficiency disrupts lipid metabolism and autophagy in mice.
NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma.
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.
CIRBP Enhances the Function of Yak Cumulus Cells by Activating AMPK/mTOR-Mediated Mitophagy.
Chicken interferon-induced transmembrane proteins inhibit Newcastle disease virus infection by affecting viral entry and W protein expression.
Ultrasound Visualization of Spatiotemporal Autophagy-Regulated Nanodroplets for Amplifying ICB in Melanoma via Remodeling Tumor Inflammatory Microenvironment.
Heat shock protein A1 inhibits the replication of foot-and-mouth disease virus by degrading viral RNA polymerase 3D through chaperone-mediated autophagy.
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Lysionotin promoted apoptosis of hepatocellular carcinoma cells via inducing autophagy.
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis.
A therapeutic strategy integrating ultrasound-guided microwave ablation with nanocomposite hydrogels to enhance autophagy and suppress tumor growth in hepatocellular carcinoma.
Lactoferrin Alleviates LPS-Induced Oxidative Stress and Necroptosis in Liver by Promoting Mitophagy.
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Hsp90 and HIF-1α regulate mitophagy by promoting BNIP3 expression in renal ischemia-reperfusion injury.
Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat via enhancement of METTL14-mediated m6A methylation of Aldh1l1.
Protein regulator of cytokinesis 1 regulates autophagy in hepatitis B virus‑associated liver cancer development.
Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin-Driven TFEB Nuclear Translocation.
Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target.
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation.
Investigating the role of IL-6 in the pathogenesis of systemic lupus erythematosus: Insights from bone marrow mesenchymal stem cells.
Eravacycline improves the efficacy of anti-PD1 immunotherapy via AP1/CCL5 mediated M1 macrophage polarization in melanoma.
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
Bisdemethoxycurcumin mitigates traumatic brain injury in rats by modulating autophagy and oxidative stress via heat shock protein 90 alpha family class A member 1-mediated nuclear translocation of transcription factor EB.
Oral exposure to nanoplastics altered lipid profiles in mouse intestine.
Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma.
PIWI-interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation.
Oxymatrine alleviates ALD-induced cardiac hypertrophy by regulating autophagy via activation Nrf2/SIRT3 signaling pathway.
HMGB1 secretion by resveratrol in NSCLC: A pathway to ferroptosis-mediated platelet activation suppression.
Wnt5a alleviates the symptoms of PCOS by modulating PI3K/AKT/mTOR pathway-mediated autophagy in granulosa cells.
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Targeting TTK Inhibits Tumorigenesis of T-Cell Lymphoma Through Dephosphorylating p38α and Activating AMPK/mTOR Pathway.
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Irisin promotes autophagy and attenuates NLRP3 inflammasome activation in Parkinson's disease.
The CRISPR/Cas9-Mediated Knockout of VgrG2 in Wild Pathogenic E. coli to Alleviate the Effects on Cell Damage and Autophagy.
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Programmed enhancement of endogenous iron-mediated lysosomal membrane permeabilization for tumor ferroptosis/pyroptosis dual-induction.
Umbelliferone attenuates calcium oxalate crystal-induced renal injury and inflammation by attenuating autophagy through the PI3K/AKT pathway.
Effects of Melatonin on H(2)O(2)-Induced Oxidative Damage of the Granulosa Cells in Hen Ovarian Follicles.
CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.
Rapamycin mitigates neurotoxicity of fluoride and aluminum by activating autophagy through the AMPK/mTOR/ULK1 pathway in hippocampal neurons and NG108-15 cells.
SAP30, a novel autophagy regulatory gene in neuroblastoma.
Dietary phytosterol supplementation mitigates renal fibrosis via activating mitophagy and modulating the gut microbiota.
Sulfur dioxide increases testosterone biosynthesis by activating ERK1/2 pathway and disrupting autophagy in Leydig cells.
Angiopoietin-2 regulates the phenotypic switch of vascular smooth muscle cells.
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.
HTLV-1 Tax induces PINK1-Parkin-dependent mitophagy to mitigate activation of the cGAS-STING pathway.
Lactobacillus plantarum SMUM211204 Exopolysaccharides Have Tumor-Suppressive Effects on Colorectal Cancer by Regulating Autophagy via the mTOR Pathway.
Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation.
Triclosan Caused Oocyte Meiotic Arrest by Modulating Oxidative Stress, Organelle Dysfunctions, Autophagy, and Apoptosis in Pigs.
Glycidol induces necroptosis and inflammation through autophagy-necrosome pathway in renal cell and mice.
Wnt1 oversees microglial activation by the Wnt/LRP5/6 receptor signaling pathway during lipopolysaccharide-mediated toxicity.
Antimony-induced hippocampal neuronal impairment through ferroptosis activation from NCOA4-mediated ferritinophagy.
Inhibition of autophagy attenuates cognitive decline and mitochondrial dysfunction in an Alzheimer's disease mouse model with chronic cerebral hypoperfusion.
Modification of RNF183 via m6A Methylation Mediates Podocyte Dysfunction in Diabetic Nephropathy by Regulating PKM2 Ubiquitination and Degradation.
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Cholesterol-dependent Nsp5-endosomes co-trafficking to lysosomes facilitates porcine reproductive and respiratory syndrome virus replication by activating autophagy.
Melatonin attenuates inflammatory bone loss by alleviating mitophagy and lactate production.
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
A bacterial RING ubiquitin ligase triggering stepwise degradation of BRISC via TOLLIP-mediated selective autophagy manipulates host inflammatory response.
Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
An erythroid-biased FOS(hi) hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia.
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer.
Identification of molecular subtypes and a prognostic risk model based on mitochondrial dynamic related genes in clear cell renal cell carcinoma.
Proteomics based discovery of Salvia miltiorrhiza Bunge treating Parkinson's disease through the PINK1/Parkin pathway.
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy.
5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer.
Triptonide facilitates autophagy-mediated apoptosis in esophageal squamous cell carcinoma by targeting the AMPK-mTOR-ULK1 axis.
Impact of ATF6 deletion on the embryonic brain development.
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitophagy.
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Pomalidomide promotes macrophage control of Mycobacterium tuberculosis via enhancing HDAC6-mediated autophagy.
Exposure of the human placental primary cells to nanoplastics induces cytotoxic effects, an inflammatory response and endocrine disruption.
CD44 Deficiency Induces Combinatory NRF2 Inhibition and Endoplasmic Reticulum Stress-Associated Dyserythropoiesis.
Developmental programming: mechanisms of early exposure to real-life chemicals in biosolids on offspring ovarian dynamics†.
Melatonin attenuates kidney injury by alleviating lysosomal damage in diabetic kidney disease.
Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.
Molecular mechanism of rapamycin-induced autophagy activation to attenuate smoking-induced COPD.
The compound XueShuanTong promotes podocyte mitochondrial autophagy via the AMPK/mTOR pathway to alleviate diabetic nephropathy injury.
ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis.
Activation of LAMP1-mediated lipophagy by sulforaphane inhibits cellular senescence and intervertebral disc degeneration.
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy.
TRIM21-driven K63-linked ubiquitination of RBM38c, as a novel interactor of BECN1, contributes to DNA damage-induced autophagy.
Sevoflurane: A dual modulator of miR‑211‑5p and mitochondrial apoptosis in glioma therapy.
Encephalomyocarditis virus non-structural protein 2C induces the degradation of NDP52 autophagy protein to promote its own survival.
Visualizing bulk autophagy in vivo by tagging endogenous LC3B.
Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Sex-dependent effects of heat exposure on the middle ear health in mice.
TREM2 inhibits LPS-induced pyroptosis and inflammation by promoting mitophagy via SYK in BV2 cells.
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Localized brain stimulation with mild magnetic hyperthermia promotes microglia activity towards reactive and autophagic phenotypes in vivo.
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Dysfunction of Autophagy in Adipose Tissue Macrophages Regulated via FoxO1 in Obesity-Related Severe Acute Pancreatitis.
Jianpi Huayu decoction enhances the antitumor effect of doxorubicin via piezo1-mediated autophagy in hepatocellular carcinoma.
Paeonol ameliorates diabetic nephropathy by promoting TFEB-mediated lysosome biogenesis and lipophagy.
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy.
Fufang zhenzhu tiaozhi capsule alleviates hypothalamic endoplasmic reticulum stress and leptin resistance through autophagy modulation in DIO rats.
Lichong Decoction represses colorectal cancer progression via inhibiting the PINK1/Parkin pathway regulated by Rab27B.
The RNF8/OPTN/KDM6A axis controls macrophage polarization to maintain testicular microenvironment homeostasis.
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
MARCH6 suppresses Tembusu virus replication by targeting viral NS5 protein for TOLLIP-mediated selective autophagic degradation.
Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.
Ursolic acid affects autophagy and apoptosis of breast cancer through PLK1 via AKT/mTOR signaling pathway.
A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses.
Uridine alleviates the aging of alveolar epithelial cells in idiopathic pulmonary fibrosis through the Keap1-Nrf2 signaling pathway.
Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter.
NKD1 enhances colon cancer progression by inhibiting the autophagic degradation of MYC.
Kumatakenin alleviates depressive-like behaviors by suppressing excessive autophagy in hippocampus via ATG5.
MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro.
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy.
DHX9-mediated epigenetic silencing of BECN1 contributes to impaired autophagy and tumor progression in breast cancer via recruitment of HDAC5.
Hsa_circ_0016662 acts as a prognostic biomarker and promotes the progression of hepatocellular carcinoma via autophagy regulation.
Self-propelled smart nanomotors for enhanced mild photothermal therapy of tumors through autophagy modulation.
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.
Viruses hijack FPN1 to disrupt iron withholding and suppress host defense.
A gain-of-function mutation in ATP6V0A4 drives primary distal renal tubular alkalosis with enhanced V-ATPase activity.
Discovery of structurally diverse diazatricyclododecenes as lysosomotropic autophagy inhibitors.
Impact of quercetin on autophagy and apoptosis induced by a high concentration of CuSO(4) in porcine ovarian granulosa cells.
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4.
PCSK9 promotes vascular neointimal hyperplasia through non-lipid regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
METTL3 methylated KIF15 promotes nasopharyngeal carcinoma progression and radiation resistance by blocking ATG7-mediated autophagy through the activation of STAT3 pathway.
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy.
Dapagliflozin improves the dysfunction of human umbilical vein endothelial cells (HUVECs) by downregulating high glucose/high fat-induced autophagy through inhibiting SGLT-2.
Mitigation of high-fat diet-induced sarcopenia by Toona sinensis fruit extracts via autophagic flux and mitochondrial quality control.
LAPTM5 Confers the Resistance to Venetoclax via Promoting the Autophagosome-Lysosome Fusion in Multiple Myeloma.
Inhibiting UGCG prevents PRV infection by decreasing lysosome-associated autophage.
Lack of retinal degeneration in a Dram2 knockout mouse model.
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons.
Phosphorylation of the selective autophagy receptor TAX1BP1 by TBK1 and IKBKE/IKKi promotes ATG8-family protein-dependent clearance of MAVS aggregates.
Paeoniflorin ameliorates reperfusion injury in H9C2 cells through SIRT1-PINK1/parkin-mediated mitochondrial autophagy.
Porphyromonas gingivalis-induced autophagy exacerbates abnormal lung homeostasis: An in vivo and in vitro study.
Inhibition of ACSS2 triggers glycolysis inhibition and nuclear translocation to activate SIRT1/ATG5/ATG2B deacetylation axis, promoting autophagy and reducing malignancy and chemoresistance in ovarian cancer.
POU4F1 enhances lung cancer gemcitabine resistance by regulating METTL3-dependent TWF1 mRNA N6 adenosine methylation.
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
STIM1 promotes cervical cancer progression through autophagy activation via TFEB nuclear translocation.
The BET inhibitor JQ1 suppresses tumor survival by ABCB5-mediated autophagy in uveal melanoma.
Oxycodone attenuates endotoxin-induced acute lung injury by regulating mitophagy via the HO-1 pathway.
Rapamycin ameliorates inflammatory pain via recovery of autophagy flux mediated by mammalian target of rapamycin (mTOR) signaling pathway in the rat spinal cord.
Exosomes From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Oxidative Stress-Induced POI by Regulating Autophagic Homeostasis Through the AMPK Pathway.
Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway.
Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord.
Uncovering the epigenetic regulatory clues of PRRT1 in Alzheimer's disease: a strategy integrating multi-omics analysis with explainable machine learning.
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Hsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation.
Drug pairs of Huangqi and Dnggui alleviates pyroptosis by promoting autophagy activity via AMPK/mTOR signaling pathway in middle-cerebral artery occlusion/reperfusion in rats.
Po-Ge-Jiu-Xin decoction alleviate sepsis-induced cardiomyopathy via regulating phosphatase and tensin homolog-induced putative kinase 1 /parkin-mediated mitophagy.
Dapagliflozin and Sirtuin-1 interaction and mechanism for ameliorating atrial fibrillation in a streptozotocin-induced rodent diabetic model.
Melatonin Mitigates Acidosis-Induced Neuronal Damage by Up-Regulating Autophagy via the Transcription Factor EB.
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis.
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Sulforaphane regulation autophagy-mediated pyroptosis in autoimmune hepatitis via AMPK/mTOR pathway.
The role of HIF-1α/BNIP3/mitophagy in acrylonitrile-induced neuronal death in HT22 cells and mice: A potential neuroprotection target.
Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence.
Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens.
Beclin 1-Mediated Autophagy Is Potentiated by an Interaction with the Neuronal Adaptor FE65.
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.
ZFAND6 promotes TRAF2-dependent mitophagy to restrain cGAS-STING signaling.
Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.
PLIN5 contributes to lipophagy of hepatic stellate cells induced by inorganic arsenic.
Deapioplatycodin D inhibits glioblastoma cell proliferation by inducing BNIP3L-mediated incomplete mitophagy.
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice.
Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma.
RICTOR-mediated activation of AKT/mTOR signaling and autophagy inhibition promote osteoarthritis.
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis.
CAVIN2 attenuates ventilator-induced lung injury in rats by MAPK/ERK1/2 signaling pathway.
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis.
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy.
Investigation of oral toxicity of WS(2) nanosheets to mouse intestine: Pathological injury, trace element balance, lipid profile changes, and autophagy.
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
A quinolinyl analog of resveratrol improves neuronal damage after ischemic stroke by promoting Parkin-mediated mitophagy.
Hypoxia-inducible factor-1α promotes ferroptosis by inducing ferritinophagy and promoting lactate production in yak longissimus thoracis et lumborum postmortem.
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
N(6)-Methyladenosine modification mediated by METTL3 promotes DNA-PKcs expression to induce anlotinib resistance in osteosarcoma.
The effect and mechanism of atorvastatin regulating PI3K-Akt-mTOR pathway on radiosensitivity of hepatocellular carcinoma cells.
Salvianolic acid B improves diabetic skin wound repair through Pink1/Parkin-mediated mitophagy.
CDC20-Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma.
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.
Autophagy is involved in the toxicity of the biocontrol agent GC16 against Tetranychus pueraricola (Acari: Tetranychidae) based on transcriptomic and proteomic analyses.
Beclin1 regulates yak endometrial inflammation and TLR4/NF-κB signaling pathway through autophagy/non-autophagy function.
Therapeutic effect of dihydroartemisinin on Alzheimer's disease model mice with senile macular degeneration.
Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling.
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Exposure to Nanoplastics During Pregnancy Induces Brown Adipose Tissue Whitening in Male Offspring.
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster.
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis.
In vitro analysis of the molecular mechanisms of ursolic acid against ovarian cancer.
THSWD upregulates the LTF/AMPK/mTOR/Becn1 axis and promotes lysosomal autophagy in hepatocellular carcinoma cells by regulating gut flora and metabolic reprogramming.
Paeoniflorin Inhibits Porcine Circovirus Type 2 Replication by Inhibiting Autophagy and Targeting AKT/mTOR Signaling.
Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling.
RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene.
Layered Double Hydroxide LDH-Loaded miR-141-3p Targets RAB10 Suppressing Cellular Autophagy to Reverse Paclitaxel Resistance in Breast Cancer.
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Chondrocyte-targeted bilirubin/rapamycin carrier-free nanoparticles alleviate oxidative stress and modulate autophagy for osteoarthritis therapy.
Berberine attenuates obesity-induced skeletal muscle atrophy via regulation of FUNDC1 in skeletal muscle of mice.
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.
20(R)-ginsenoside Rg3 protects against focal cerebral ischemia‒reperfusion injury by suppressing autophagy via PI3K/Akt/mTOR signaling pathway.
Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.
Mammalian Sterile 20-Like Kinase 2 Knockdown Alleviates Neuropathic Pain in Rats by Mitochondrial Protection.
Personalized Cancer Immunotherapy Boosted by cGAS-STING-Targeted Nanovaccines in Combination With Nutrient Modulation.
RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression.
L1CAM enhances autophagy via inhibition of p38 phosphorylation in colorectal cancer development and progression.
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Biomolecule-tailored chiral nickel oxide nanozymes amplify autophagy-mediated tumor ablation via synergistic photodynamic-chemodynamic therapy.
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Regulation of nuclear transport of the transcriptional factor REST improves axon regeneration in peripheral nerves.
Traditional Chinese Medicinal Leech Induces Apoptosis and Autophagy in Glioblastoma by SGK1/Caspase-3 and PI3K/AKT/mTOR Pathway.
Sesamin alleviates drug-induced hepatotoxicity via autophagy enhancement and ferroptosis inhibition.
The umbilical cord blood exosome MFG-E8 alleviates hypoxic-ischemic encephalopathy brain injury in neonatal rats by restoring autophagy flux and inhibiting ferroptosis through GSK3β/β-catenin signaling.
COX-2 targeting Ru-arene complexes from metal-ligand synergistic enhancement strategy for breast cancer therapy.
Cytosolic TOP3α facilitates mitochondrial DNA sensing by cGAS.
Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.
Dietary monounsaturated fatty acid facilitates lipid droplet turnover through chaperone HSP90A-mediated lysosomal degradation of PLIN2 in hepatocellular carcinoma.
Excessive autophagic degradation of MYLK3 causes sunitinib-induced cardiotoxicity.
Pseudorabies virus gM protein and herpesvirus homologs block selective autophagy to enhance viral replication.
m6A Methylation-Induced Autophagy Impairment by TFEB Regulation in SOD1-G93A ALS Cell Model.
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke.
MiR-646 inhibited cell proliferation and migration by targeting P62 in glioma.
Matrix stiffness-sensitive LDHA drives autophagy of pancreatic ductal adenocarcinoma via inducing FOXO3 expression and lactylation.
Laminar double hydroxide-loaded miR-654-3p targets POU2F1-mediated metabolic reprogramming against colorectal cancer.
Artemisia argyi ethyl acetate fraction suppresses ovarian cancer progression via JUN/MAPK10 signaling: An integrated multi-omics investigation.
Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.
WDR4-mediate tRNA m7G modification to promote mitophagy and browning of white adipose tissue for ameliorating obesity in male mice.
PARP inhibitors accumulate B7-H3 on fibroblasts via blocking autophagic flux to potentiate immune evasion in ovarian cancer.
Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impairing mitochondrial function and autophagic flux.
Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells.
Liposomal honokiol enhance the anti-tumor effect of bevacizumab in glioblastoma by inhibiting autophagy.
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
Research note: duck Tembusu virus non-structural protein 3 induced autophagy through endoplasmic reticulum stress.
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
OPRK1 drives SLC9A3R1 progression to neuroendocrine prostate cancer.
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Molecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy.
Lack of intestinal Mucin-1 impairs intestinal epithelial barrier and promotes metabolic dysfunction-associated steatotic liver disease in male mice.
Identification of ferroptosis-related genes as diagnostic biomarkers and therapeutic targets in sorafenib-resistant HCC via machine learning and experimental validation.
Regulation of autophagy by oncogene DJ1 via the JNK signaling pathway in human ovarian cancer cells.
Synthesis and Biological Evaluation of a Caffeic Acid Phenethyl Ester Derivatives as Anti-Hepatocellular Carcinoma Agents via Inhibition of Mitochondrial Respiration and Disruption of Cellular Metabolism.
Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.
Propofol addiction drives neuronal senescence and cognitive decline via autophagy-mediated ADAR1/SIRT1 disruption.
Does hypoxemia aggravate sepsis-associated acute kidney injury? Integrated clinical and experimental evidence.
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Effects of psychosocial stress on myocardial injury by modulating endoplasmic reticulum stress-induced autophagy and inflammation.
Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy-lysosomal pathway: an experimental study.
Platelet-hitchhiking triiodothyronine nanoparticles for enhanced therapy of cerebral ischemia-reperfusion injury.
Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.
Liraglutide alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic rats by enhancing mitophagy mediated by the AMPK-Parkin signaling pathway.
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
Fibrotic collagen-targeted delivery system blocks pancreatic intercellular crosstalk to alleviate pancreatic fibrosis.
A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13.
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Discovery of a novel mitophagy inducer attenuating postoperative cognitive dysfunction through structure-based virtual screening and biological validation.
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
mTORC1-dependent suppression of autophagic activity in somatic cell nuclear transfer mouse embryos.
Tooth Loss Leads to Cognitive Impairment and Mitochondrial Disturbance in Wistar Rats.
Salidroside sensitizes Triple-negative breast cancer to ferroptosis by SCD1-mediated lipogenesis and NCOA4-mediated ferritinophagy.
Effect of spermidine on cuproptosis in follicular granulosa cells.
Demethylzeylasteral inhibits proliferation and metastasis of osteosarcoma cells by modulating the PI3K/AKT/Autophagy pathways.
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
A biomimetic multimodal nanoplatform combining neutrophil-coated two-dimensional metalloporphyrinic framework nanosheet and exendin-4 to treat obesity-related osteoporosis.
Reduced iron bioavailability drives acute high‑altitude lung injury through HIF1α activation and mitophagy.
Zika virus capsid protein impairs neural differentiation.
Zn(2+)-driven metformin conjugated with siRNA attenuates osteoarthritis progression by inhibiting NF-κB signaling and activating autophagy.
Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
Cilostazol attenuates vascular inflammation via the regulation of TICAM1/IRF3 signaling pathway.
Biliverdin alleviates cerebral ischemia-reperfusion injury by regulating the P4hb/MAPK/mTOR pathway to inhibit autophagy.
β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.
NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA.
Whey protein hydrolysate alleviated acetaminophen-induced hepatocyte pyroptosis by activating mitophagy.
c-FLIP Protects Cardiac Microcirculation in Sepsis-Induced Myocardial Dysfunction Via FUNDC1-Mediated Regulation of Mitochondrial Autophagy.
1,3-Dichloro-2-propanol Causes Lipid Droplet Accumulation by Inhibiting Autophagy via REV-ERBα in Hepatocytes.
Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.
Genetic depletion of early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Hyperoxia-induced oxidative stress enhances TMEM106B to impair ULK1-mediated autophagy via TLR3/JNK signaling.
MCOLN1-Mediated Endoplasmic Reticulum Stress Induces Autophagy to Facilitate Lung Cancer Growth, Migration, and Invasion.
Identifying Key Genes of Proanthocyanidin Intervention in Fluoride-Induced Liver Injury: Integrated Molecular Docking and Experimental Validation.
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
Exosomes derived from umbilical cord mesenchymal stem cells alleviate jaw bone marrow mesenchymal stem cells senescence and restore osteogenic differentiation potential.
Melatonin-induced ferroptosis in pancreatic cancer cells by stimulating endoplasmic reticulum stress and inhibiting alanine-serine-cysteine transporter 2-driven glutamine metabolism.
PP2A attenuates α-amanitin-induced liver injury by promoting autophagy and inhibiting apoptosis in mouse models.
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
ETAS(®), a Standardized Extract of Asparagus officinalis Stem, Alleviates Sarcopenia via Regulating Protein Turnover and Mitochondrial Quality.
NDUFB9 ameliorates CUMS-induced depression-like behavior by promoting mitophagy.
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs.
Cardamonin inhibits the growth and stemness of osteosarcoma stem cells by inducing autophagy and inhibiting the Wnt/β-catenin signaling pathway.
Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.
Cordycepin Ameliorates Kainic Acid-Induced HT22 Cell Neurotoxicity by Activating GPR120-Mediated Mitophagy.
TRIM36 Inhibits the Development of AOM/DSS-Induced Colitis-Associated Colorectal Cancer by Promoting the Ubiquitination and Degradation of GRB7.
Neuroprotective Effects of AER-271 in a tMCAO Mouse Model: Modulation of Autophagy, Apoptosis, and Inflammation.
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
The Mechanistic Study of Mitochondrial Autophagy and Ferroptosis in the Progression of Decreased Ovarian Reserve.
VDAC1 Inhibition Protects Against Noise-Induced Hearing Loss via the PINK1/Parkin Pathway.
Mycoplasma ovipnuemoniae impairs the immune response of sheep and suppresses neutrophil function by inhibiting S100A9.
Dietary cinnamon promotes longevity and extends healthspan via mTORC1 and autophagy signaling.
MitoQ alleviates H(2)O(2)-induced mitochondrial dysfunction in keratinocytes through the Nrf2/PINK1 pathway.
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation.
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
RGFP966 inhibits palmitic acid induced VSMCs phenotypic transition by targeting ATGL.
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Tetrandrine alleviates macrophage activation syndrome after CAR-T cell therapy.
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
3-D Sustained-Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells.
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
LncRNA NEAT1-206 regulates autophagy of human umbilical cord mesenchymal stem cells through the WNT5A/Ca(2+) signaling pathway under senescence stress.
Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy.
ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway.
Mechanism of Mitophagy to Protect Yak Kidney from Hypoxia-Induced Fibrosis Damage by Regulating Ferroptosis Pathway.
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis.
Retromer promotes the lysosomal turnover of mtDNA.
Tricin Delays Aging and Enhances Muscle Function via Activating AMPK-Mediated Autophagy in Diverse Model Organisms.
Antiepileptic Effects of Acorus tatarinowii Schott in a Rat Model of Epilepsy: Regulation of Metabolic Axes and Gut Microbiota.
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease.
Neferine Ameliorates Slow-Transmitting Constipation by Inducing PINK1/Parkin-Mediated Mitophagy in Protective Enteric Glial Cells.
Salvianolic Acid A Alleviates Sciatic Nerve Injury in Rats Via Inhibiting NLRP3 Inflammasome Through the Activation of Schwann Cells Autophagy.
Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced nonalcoholic steatohepatitis.
Formononetin ameliorates depression-like behaviors through rebalancing microglia M1/M2 polarization and inhibiting NLRP3 inflammasome: involvement of activating PPARα-mediated autophagy.
Apigenin-Mediated ESCRT-III Activation and Mitophagy Alleviate LPS-Induced Necroptosis in Renal Cells.
Tricetin, a Dietary Flavonoid, Alleviates Neuroinflammation and Promotes Autophagy in Alzheimer's Disease by Regulating the PI3K/Akt/mTOR Signaling Pathway.
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Hydrogen sulfide improves poststroke depression-induced inflammation in microglial cells by enhancing endoplasmic reticulum autophagy and inhibiting the cGAS-STING pathway.
PERK/Sestrin2 Signaling Pathway Mediated Autophagy Regulates Human Cardiomyocytes Apoptosis Induced by Traffic-Related PM(2.5) and Diverse Constituents.
Aging and autophagic phenotypic changes in bone marrow mesenchymal stem cells in glucocorticoid-induced osteonecrosis.
Engineered Extracellular Vesicles Derived from Juvenile Mice Enhance Mitochondrial Function in the Aging Bone Microenvironment and Achieve Rejuvenation.
Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein.
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Comprehensive profiling of lipid metabolic reprogramming expands precision medicine for HCC.
The role of TFEB-mediated autophagy-lysosome dysfunction in manganese neurotoxicity.
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis.
The role and mechanism of macrophage autophagy in the experimental model of chronic obstructive pulmonary disease.
Evidence for the potential role of m6A modification in regulating autophagy in models of amyotrophic lateral sclerosis.
The role and underlying mechanism of dental pulp stem cell-derived exosomal miR-31 in the treatment of osteoarthritis by targeting mTOR to enhance chondrocyte autophagy levels.
ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy.
Diltiazem Hydrochloride Protects Against Myocardial Ischemia/Reperfusion Injury in a BNIP3L/NIX-Mediated Mitophagy Manner.
Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.
Tanshinone IIA Promoted Autophagy and Inhibited Inflammation to Alleviate Podocyte Injury in Diabetic Nephropathy.
Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
Novel Insights from Comprehensive Bioinformatics Analysis Utilizing Large-Scale Human Transcriptomes and Experimental Validation: The Role of Autophagy in Periodontitis.
MCU promotes the migration of glioma cells by activating p38 through TFEB-mediated autophagy.
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.
Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation.
Salidroside enhances 5-fluorouracil sensitivity against hepatocellular carcinoma via YIPF5-induced mitophagy.
Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.
CRISPR/Cas9-mediated knockout of STAT1 in porcine-derived cell lines to elucidate the role of STAT1 in autophagy following classical swine fever virus infection.
Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.
Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy.
Sesamin alleviates lipid accumulation induced by elaidic acid in L02 cells through TFEB regulated autophagy.
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice.
Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies.
ent-8(14),15-Pimaradiene-2β,19-diol, a diterpene from Aleuritopteris albofusca, inhibits growth and induces protective autophagy in hepatocellular carcinoma cells.
Urolithin A exerts anti-tumor effects on gastric cancer via activating autophagy-Hippo axis and modulating the gut microbiota.
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
IGF2 promotes the differentiation of chicken embryonic myoblast by regulating mitochondrial remodeling.
The Role of BNIP3 and Blocked Autophagy Flux in Arsenic-Induced Oxidative Stress-Induced Liver Injury in Rats.
Mechanisms of programmed cell death associated to severe dengue in human renal lesions.
JAK2 inhibitor protects the septic heart through enhancing mitophagy in cardiomyocytes.
Enhanced glioma cell death with ZnO nanorod flowers and temozolomide combination therapy through autophagy and mitophagy pathways.
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
The role of DNA damage response in human embryonic stem cells exposed to atmospheric oxygen tension: Implications for embryo development and differentiation.
Lidamycin induces mitophagy in pancreatic cancer cells by regulating the expression of Mfn2.
Effects of the lncRNA NBR2 on the proliferation and autophagy of breast cancer cells under starvation conditions.
Platelets promote primary hepatocellular carcinoma metastasis through TGF-β1-mediated cancer cell autophagy.
CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC.
Autophagy defects at weaning impair complement-dependent synaptic pruning and induce behavior deficits.
Lipid droplets sequester palmitic acid to disrupt endothelial ciliation and exacerbate atherosclerosis in male mice.
A Lysosome-Targeting hNEU1 Inhibitor Treats Myocardial Infarction: A Potential Therapeutic Breakthrough.
Construction of a Multifunctional Upconversion Nanoplatform Based on Autophagy Inhibition and Photodynamic Therapy Combined with Chemotherapy for Antitumor Therapy.
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Follicular fluid HD-sevs-mir-128-3p is a key molecule in regulating bovine granulosa cells autophagy.
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma.
DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment.
Autophagy aggravates multi-walled carbon nanotube-induced ferroptosis by suppressing PGC-1 dependent-mitochondrial biogenesis in lung epithelial cells.
Lubricin-Inspired Nanozymes Reconstruct Cartilage Lubrication System with an "In-Out" Strategy.
Placental growth factor alleviates hyperglycemia-induced trophoblast pyroptosis by regulating mitophagy.
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
Circadian gene CLOCK accelerates atherosclerosis by promoting endothelial autophagy.
Regulation of autophagy by ST3GAL2-mediated α2-3 sialylated glycosphingolipids in hepatic encephalopathy.
Mfn2(R364W), Mfn2(G176S), and Mfn2(H165R) mutations drive Charcot-Marie-Tooth type 2A disease by inducing apoptosis and mitochondrial oxidative phosphorylation damage.
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise.
Sestrin2 plays a protective role in age-related hearing loss by inhibiting NLRP3-inflammasome activity.
Bunyavirus SFTSV NSs utilizes autophagy to escape the antiviral innate immune response.
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Targeting SMYD2 promotes ferroptosis and impacts the progression of pancreatic cancer through the c-Myc/NCOA4 axis-mediated ferritinophagy.
Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS, ER stress, and blocked autophagy.
Neuroprotective Effect of Melatonin in a Neonatal Hypoxia-Ischemia Rat Model Is Regulated by the AMPK/mTOR Pathway.
Functional Relationships between L1CAM, LC3, ATG12, and Aβ.
Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice.
Targeting oncogenic MAGEA6 sensitizes triple negative breast cancer to doxorubicin through its autophagy and ferroptosis by stabling AMPKα1.
Ganoderic acid A mitigates dopaminergic neuron ferroptosis via inhibiting NCOA4-mediated ferritinophagy in Parkinson's disease mice.
Antitumor activity and transcriptome sequencing (RNA-seq) analyses of hepatocellular carcinoma cells in response to exposure triterpene-nucleoside conjugates.
MiR-155-5p regulates autophagy and apoptosis of glioma cells through RICTOR.
The RNA N6-methyladenosine demethylase FTO regulates ATG5 to inhibit malignant progression of uveal melanoma.
HSP90 Enhances Mitophagy to Improve the Resistance of Car-Diomyocytes to Heat Stress in Wenchang Chickens.
Myocardial ischemia-reperfusion injury upregulates nucleostemin expression via HIF-1α and c-Jun pathways and alleviates apoptosis by promoting autophagy.
Inhibition of endoplasmic reticulum stress and excessive autophagy by Jiedu Tongluo Tiaogan Formula via a CaMKKβ/AMPK pathway contributes to protect pancreatic β-cells.
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation.
Luteolin Protects against Vascular Calcification by Modulating SIRT1/CXCR4 Signaling Pathway and Promoting Autophagy.
PRDM1 promotes nucleus pulposus cell pyroptosis leading to intervertebral disc degeneration via activating CASP1 transcription.
A TBK1-independent primordial function of STING in lysosomal biogenesis.
The Integrated Stress Response Suppresses PINK1-dependent Mitophagy by Preserving Mitochondrial Import Efficiency.
RABIF promotes hepatocellular carcinoma progression through regulation of mitophagy and glycolysis.
METTL3 mediates m6A modification of lncRNA CRNDE to promote ATG10 expression and improve brain ischemia/reperfusion injury through YTHDC1.
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1.
Black phosphorus nanosheets induce autophagy dysfunction by a size- and surface modification-related impairment of lysosomes in macrophages.
Silica nanoparticles cause ovarian dysfunction and fertility decrease in mice via oxidative stress-activated autophagy and apoptosis.
Nur77 ameliorates cyclophosphamide-induced ovarian insufficiency in mice by inhibiting oxidative damage and cell senescence.
Tumor-associated macrophages/C-X-C motif chemokine ligand 1 promotes breast cancer autophagy-mediated chemoresistance via IGF1R/STAT3/HMGB1 signaling.
Ursodeoxycholic Acid Platinum(IV) Conjugates as Antiproliferative and Antimetastatic Agents: Remodel the Tumor Microenvironment through Suppressing JAK2/STAT3 Signaling.
Continuous Theta Burst Stimulation Inhibits Oxidative Stress-Induced Inflammation and Autophagy in Hippocampal Neurons by Activating Glutathione Synthesis Pathway, Improving Cognitive Impairment in Sleep-Deprived Mice.
GL-V9 Promotes Autophagy-Mediated YAP1 Degradation and Activates Mitochondrial Apoptosis in PDAC Cells.
Leptin promotes tendon stem/progenitor cell senescence through the AKT-mTOR signaling pathway.
Hesperetin alleviates aflatoxin B1 induced liver toxicity in mice: Modulating lipid peroxidation and ferritin autophagy.
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway.
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Ferritinophagy is involved in hexavalent chromium-induced ferroptosis in Sertoli cells.
Propyl acetate protects intestinal barrier during parenteral nutrition in mice and Caco-2 cells.
Influences of TiO(2) nanoparticle and fipronil co-exposure on metabolite profiles in mouse intestines.
High levels of mitochondrial dynamics, autophagy, and apoptosis contribute to stable testicular status in hibernating Daurian ground squirrels.
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Ciclopirox platinum(IV) conjugates suppress tumors by promoting mitophagy and provoking immune responses.
Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8(+) T cells.
Angiopoietin 1 Relieves Osteolysis by Promoting Macrophage Mitophagy Through the TBK1-SQSTM1 Pathway to Inhibit AIM2 Inflammasome-Mediated Pyroptosis.
Cereblon mediates macrophage differentiation and microglial phagocytosis by regulating calpain protease activity.
GBF1 deficiency causes cataracts in human and mouse.
SEC31a-ATG9a Interaction Mediates the Recruitment of COPII Vesicles for Autophagosome Formation.
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus.
Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways.
Multi-protomics analysis identified host cellular pathways perturbed by tick-borne encephalitis virus infection.
Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.
Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation.
Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.
Paeoniflorin Inhibits the Activation of Microglia and Alleviates Depressive Behavior by Regulating SIRT1-NF-kB-NLRP3/Pyroptosis Pathway.
Tripartite motif 25 inhibits protein aggregate degradation during PRRSV infection by suppressing p62-mediated autophagy.
EYA3 promotes the tumorigenesis of gastric cancer through activation of the mTORC1 signaling pathway and inhibition of autophagy.
STAT3 Inhibitor Increases α-Synuclein in PFF-Treated Astroglia Cells by Dysregulating Autophagy and Potentially Affects Exosome Biogenesis.
PI3K p85α/HIF-1α accelerates the development of pulmonary arterial hypertension by regulating fatty acid uptake and mitophagy.
Cremastrae Pseudobulbus Pleiones Pseudobulbus (CPPP) Against Non-Small-Cell Lung Cancer: Elucidating Effective Ingredients and Mechanism of Action.
NLRX1 and STING alleviate renal ischemia-reperfusion injury by regulating LC3 lipidation during mitophagy.
Soybean isoflavones protect dopaminergic neurons from atrazine damage by inhibiting VPS13A to increase autophagy.
Gaudichaudione H ameliorates liver fibrosis and inflammation by targeting NRF2 signaling pathway.
Unconjugated bilirubin promotes uric acid restoration by activating hepatic AMPK pathway.
Lanthanum chloride exerts therapeutic potential for chronic kidney disease by suppressing nanohydroxyapatite-induced mitophagy and mitochondria-mediated apoptosis.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
An enzyme-responsive double-locked amonafide prodrug for the treatment of glioblastoma with minimal side effects.
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level.
Dihydroartemisinin eliminates senescent cells by promoting autophagy-dependent ferroptosis via AMPK/mTOR signaling pathway.
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Platelet factor 4 promotes deep venous thrombosis by regulating the formation of neutrophil extracellular traps.
Transcription factor FOXM1 specifies chromatin DNA to extracellular vesicles.
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis.
Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Aucubin alleviates doxorubicin-induced cardiotoxicity through crosstalk between NRF2 and HIPK2 mediating autophagy and apoptosis.
Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway.
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity.
p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.
Varespladib mitigates acute liver injury via suppression of excessive mitophagy on Naja atra envenomed mice by inhibiting PLA(2).
Inhibition of NLRP3 inflammasome by MCC950 under hypoxia alleviates photoreceptor apoptosis via inducing autophagy in Müller glia.
Oxidative medicine and cellular longevity the role and mechanism of NCOA4 in ferroptosis induced by intestinal ischemia reperfusion.
Chondroprotective effects of Apolipoprotein D in knee osteoarthritis mice through the PI3K/AKT/mTOR signaling pathway.
Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy.
SS-31 inhibits the inflammatory response by increasing ATG5 and promoting autophagy in lipopolysaccharide-stimulated HepG2 cells.
Label-Free Three-Dimensional Morphological Characterization of Cell Death Using Holographic Tomography.
Pectinose induces cell cycle arrest in luminal A and triple-negative breast cancer cells by promoting autophagy through activation of the p38 MAPK signaling pathway.
Galectin-receptor interaction: a key player in liver fibrosis induced by Schistosoma japonicum infection.
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
D-arabinose induces cell cycle arrest by promoting autophagy via p38 MAPK signaling pathway in breast cancer.
The polysaccharides from Balanophora polyandra enhanced neuronal autophagy to ameliorate brain function decline in natural aging mice through the PI3K/AKT/mTOR signaling pathway.
Cadmium exposure induced neuronal ferroptosis and cognitive deficits via the mtROS-ferritinophagy pathway.
Sialyltransferase ST3GAL6 silencing reduces α2,3-sialylated glycans to regulate autophagy by decreasing HSPB8-BAG3 in the brain with hepatic encephalopathy.
Mangiferin attenuates lipopolysaccharide-induced neuronal injuries in primary cultured hippocampal neurons.
Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells.
Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.
MicroRNA-144-3p Inhibits Host Lipid Catabolism and Autophagy by Targeting PPARα and ABCA1 During Mycobacterium Tuberculosis Infection.
TIMP2 protects against sepsis-associated acute kidney injury by cAMP/NLRP3 axis-mediated pyroptosis.
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Autophagy activity is increased in the cumulus cells of women with poor ovarian response.
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia.
Local delivery of EGFR(+)NSCs-derived exosomes promotes neural regeneration post spinal cord injury via miR-34a-5p/HDAC6 pathway.
Mitochondrial-targeting and NIR-responsive Mn(3)O(4)@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis.
RACK1 promotes autophagy via the PERK signaling pathway to protect against traumatic brain injury in rats.
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
CDK12 inhibition upregulates ATG7 triggering autophagy via AKT/FOXO3 pathway and enhances anti-PD-1 efficacy in colorectal cancer.
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Corydecusines A-H, new phthalideisoquinoline hemicetal alkaloids from the bulbs of Corydalis decumbens inhibit Tau pathology by activating autophagy mediated by AMPK-ULK1 pathway.
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression.
Metformin alleviates junctional epithelium senescence via the AMPK/SIRT1/autophagy pathway in periodontitis induced by hyperglycemia.
Integrated network pharmacology and phosphoproteomic analyses of Baichanting in Parkinson's disease model mice.
ALKBH5 suppresses autophagic flux via N6-methyladenosine demethylation of ZKSCAN3 mRNA in acute pancreatitis.
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis.
Identification of a ferritinophagy inducer via sinomenine modification for the treatment of colorectal cancer.
Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair.
Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Enhances foxo1-Mediated Lipophagy to Remodel Lipid Metabolism in Zebrafish Liver.
Manganese disrupts the maturation and degradation of axonal autophagosome leading to hippocampal synaptic toxicity in mice via the activation of LRRK2 on phosphorylation of Rab10.
Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
NPC1 promotes autophagy with tumor promotion and acts as a prognostic model for hepatocellular carcinoma.
Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR pathway in human granulosa cell line KGN.
Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD.
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway.
Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway.
Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated LC3B transcription in NSCLC.
Punicalagin Ameliorates Diabetic Liver Injury by Inhibiting Pyroptosis and Promoting Autophagy via Modulation of the FoxO1/TXNIP Signaling Pathway.
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Beclin 1 Haploinsufficiency Ameliorates High-Fat Diet-Induced Myocardial Injury via Inhibiting Alternative Mitophagy.
Lysine specific demethylase 1 inhibits sodium arsenite activation of HSCs by regulating SESN2/AMPK/ULK1 signaling pathway activity.
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC3.
TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA.
A Key regulatory protein QRICH2 governing sperm function with profound antioxidant properties, enhancing sperm viability.
Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy.
Reactive Oxygen Species-Mediated Mitophagy and Cell Apoptosis are Involved in the Toxicity of Aluminum Chloride Exposure in GC-2spd.
Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles.
Enhancement of autophagy can alleviate oxidative stress, inflammation, and apoptosis induced by ammonia stress in yellow catfish Pelteobagrus fulvidraco.
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
Total paeony glycoside relieves neuroinflammation to exert antidepressant effect via the interplay between NLRP3 inflammasome, pyroptosis and autophagy.
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Hypoxia-mediated programmed cell death is involved in the formation of wooden breast in broilers.
Microbial metabolite sodium butyrate enhances the anti-tumor efficacy of 5-fluorouracil against colorectal cancer by modulating PINK1/Parkin signaling and intestinal flora.
Pongamol Alleviates Neuroinflammation and Promotes Autophagy in Alzheimer's Disease by Regulating the Akt/mTOR Signaling Pathway.
Baicalin reduced injury of and autophagy-related gene expression in RAW264.7 cells infected with H6N6 avian influenza virus.
Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease.
A specific super-enhancer actuated by berberine regulates EGFR-mediated RAS-RAF1-MEK1/2-ERK1/2 pathway to induce nasopharyngeal carcinoma autophagy.
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice.
Identification of osteoblastic autophagy-related genes for predicting diagnostic markers in osteoarthritis.
Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of quercetin in hepatocellular carcinomaf.
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy.
Heyingwuzi formulation alleviates diabetic retinopathy by promoting mitophagy via the HIF-1α/BNIP3/NIX axis.
TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism.
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
3-MCPD Induces Renal Cell Pyroptosis and Inflammation by Inhibiting ESCRT-III-Mediated Cell Repair and Mitophagy.
Intestinal microbiota via NLRP3 inflammasome dependent neuronal pyroptosis mediates anxiety-like behaviour in mice exposed to 3.5 GHz radiofrequency radiation.
Hsa_circ_0096157 silencing suppresses autophagy and reduces cisplatin resistance in non-small cell lung cancer by weakening the Nrf2/ARE signaling pathway.
Exposure to nicotine regulates prostaglandin E2 secretion and autophagy of granulosa cells to retard follicular maturation in mammals.
A novel SLC3A2-targeting antibody-drug conjugate exerts potent antitumor efficacy in head and neck squamous cell cancer.
TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Mechanism Research of DHEA Treatment Improving Diminished Ovarian Reserve by Attenuating the AMPK-SIRT1 Signaling and Mitophagy.
Heme oxygenase activates calcium release from the endoplasmic reticulum of bovine mammary epithelial cells to promote TFEB entry into the nucleus to reduce the intracellular load of Mycoplasma bovis.
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro.
The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation.
Neonatal Exposure to Polystyrene Nanoplastics Impairs Microglia-Mediated Synaptic Pruning and Causes Social Behavioral Defects in Adulthood.
Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism.
Exploring the Molecular Mechanism of Schisandrin C for the Treatment of Atherosclerosis via the PI3K/AKT/mTOR Autophagy Pathway.
The cellular adaptor GULP1 interacts with ATG14 to potentiate autophagy and APP processing.
Mdivi-1 alleviates ferroptosis induced by hypoxia combined with propofol in HT22 cells by inhibiting excessive mitophagy.
LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.
Drp1 Aggravates Copper Nanoparticle-Induced ER-Phagy by Disturbing Mitochondria-Associated Membranes in Chicken Hepatocytes.
Nur77 improves ovarian function in reproductive aging mice by activating mitophagy and inhibiting apoptosis.
Microglial AKAP8L: a key mediator in diabetes-associated cognitive impairment via autophagy inhibition and neuroinflammation triggering.
Defective ferritinophagy and imbalanced iron metabolism in PBDE-47-triggered neuronal ferroptosis and salvage by Canolol.
Short-chain fatty acids mitigate Methamphetamine-induced hepatic injuries in a Sigma-1 receptor-dependent manner.
Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota.
Targeting of G protein-coupled receptor 39 alleviates angiotensin II-induced renal damage by reducing ribonucleotide reductase M2.
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia‒reperfusion injury.
HIF-1α Contributes to Hypoxia-induced VSMC Proliferation and Migration by Regulating Autophagy in Type A Aortic Dissection.
Li, P HY-021068 alleviates cerebral ischemia-reperfusion injury by inhibiting NLRP1 inflammasome and restoring autophagy function in mice.
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Glycine recalibrates iron homeostasis of lens epithelial cells by blocking lysosome-dependent ferritin degradation.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy.
Exosomal microRNA profiling revealed enhanced autophagy suppression and anti-tumor effects of a combination of compound Phyllanthus urinaria and lenvatinib in hepatocellular carcinoma.
Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA.
Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation.
Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma.
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis.
Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Ameliorate Aging-Induced BTB Impairment in Porcine Testes by Activating Autophagy and Inhibiting ROS/NLRP3 Inflammasomes via the AMPK/mTOR Signaling Pathway.
Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice.
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation.
SMYD3 activates the TCA cycle to promote M1-M2 conversion in macrophages.
Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy.
Chinese herbal medicine alleviates autophagy and apoptosis in ovarian granulosa cells induced by testosterone through PI3K/AKT1/FOXO1 pathway.
Study on the neuroprotective effect of Zhimu-Huangbo extract on mitochondrial dysfunction in HT22 cells induced by D-galactose by promoting mitochondrial autophagy.
Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a.
Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice.
Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
Effects of exercise, metformin, and combination treatments on type 2 diabetic mellitus-induced muscle atrophy in db/db mice: Crosstalk between autophagy and the proteasome.
General Control Non-derepressible 2 Alleviates Cartilage Degeneration and Inhibits NLRP3 Inflammasome Activation in Osteoarthritis.
Flavonoid 4,4'-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy.
A conserved ion channel function of STING mediates noncanonical autophagy and cell death.
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis.
PPAR γ activation in chondrocytes alleviates glucocorticoid-induced oxidative stress, mitochondrial impairment, and pyroptosis via autophagic flow enhancement.
Ferritinophagy-mediated ferroptosis of spermatogonia is involved in busulfan-induced oligospermia in the mice.
Identifying CTH and MAP1LC3B as ferroptosis biomarkers for prognostic indication in gastric cancer decoding.
[Role of mitochondrial autophagy and the curative effect of rehmannia glutinosa leaves total glycoside capsules on nucleos(t)ide drug-induced renal injury].
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1.
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression.
Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy.
Tanshinone IIA alleviates inflammation-induced skeletal muscle atrophy by regulating mitochondrial dysfunction.
HucMSC extracellular vesicles increasing SATB 1 to activate the Wnt/β-catenin pathway in 6-OHDA-induced Parkinson's disease model.
Homogeneous Polyporus polysaccharide exerts anti-bladder cancer effects via autophagy induction.
FOXG1 interaction with SATB2 promotes autophagy to alleviate neuroinflammation and mechanical abnormal pain in rats with lumbar disc herniation.
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.
Protein arginine methyltransferase 5 confers the resistance of triple-negative breast cancer to nanoparticle albumin-bound paclitaxel by enhancing autophagy through the dimethylation of ULK1.
Astaxanthin attenuates diabetic kidney injury through upregulation of autophagy in podocytes and pathological crosstalk with mesangial cells.
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway.
Enhancing retention and permeation of rapamycin for osteoarthritis therapy using a two-stage drug delivery system.
Linoleic Acid Enhances Renal Tubular Epithelial Cells Autophagy Caused by Calcium Oxalate Monohydrate Crystals.
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products.
TRPML1 ameliorates seizures-related neuronal injury by regulating autophagy and lysosomal biogenesis via Ca(2+)/TFEB signaling pathway.
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Gnetupendin A protects against ischemic stroke through activating the PI3K/AKT/mTOR-dependent autophagy pathway.
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Forsythoside A mitigates osteoarthritis and inhibits chondrocyte senescence by promoting mitophagy and suppressing NLRP3 inflammasome via the Nrf2 pathway.
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis.
Aloe Emodin Alleviates Radiation-Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption.
Rationally designed febuxostat-based hydroxamic acid and its pH-Responsive nanoformulation elicits anti-tumor activity.
CD39 inhibitor (POM-1) enhances radiosensitivity of esophageal squamous cell carcinoma (ESCC) cells by promoting apoptosis through the Bax/Bcl-2/Caspase 9/Caspase 3 pathway.
GDF11 promotes osteogenic/odontogenic differentiation of dental pulp stem cells to accelerate dentin restoration via modulating SIRT3/FOXO3-mediated mitophagy.
Tenovin-6 exhibits inhibitory effects on the growth of Sonic Hedgehog (SHH) medulloblastoma, as evidenced by both in vitro and in vivo studies.
Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus.
Molecular Insights into the Regulation of GNPTAB by TMEM251.
Fisetin Ameliorates Hepatocyte Lipid Droplet Accumulation via Targeting the Rhythmic Protein BMAL1 to Regulate Cell Death-Inducing DNA Fragmentation Factor-α-like Effector C-Mediated Lipid Droplet Fusion.
Interfering Nuclear Protein Laminb1 Induces DNA Damage and Reduces Vemurafenib Resistance in Melanoma Cells In Vitro.
Poly(allylamine)/tripolyphosphate nanocomplex coacervate as a NLRP3-dependent systemic adjuvant for vaccine development.
Hypoxia-induced TPC2 transcription and glycosylation aggravates pulmonary arterial hypertension by blocking autophagy flux.
Lactate Promotes Hypoxic Granulosa Cells' Autophagy by Activating the HIF-1α/BNIP3/Beclin-1 Signaling Axis.
Quercetin inhibits mitophagy-mediated apoptosis and inflammatory response by targeting the PPARγ/PGC-1α/NF-κB axis to improve acute liver failure.
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Stilbene glycosides alleviate atherosclerosis partly by promoting lipophagy of dendritic cells.
mTOR Inhibitor Everolimus Modulates Tumor Growth in Small-Cell Carcinoma of the Ovary, Hypercalcemic Type and Augments the Drug Sensitivity of Cancer Cells to Cisplatin.
Comparison of biocompatibility of epoxy resin and bioceramic-based root canal sealers.
2'-Hydroxycinnamaldehyde, a Natural Product from Cinnamon, Alleviates Ischemia/Reperfusion-Induced Microvascular Dysfunction and Oxidative Damage in Rats by Upregulating Cytosolic BAG3 and Nrf2/HO-1.
Visualizing ER-phagy and ER architecture in vivo.
LOC730101 improves ovarian cancer drug sensitivity by inhibiting autophagy-mediated DNA damage repair via BECN1.
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway.
Discovery of sp(3)-rich diazatricycloundecanes as lysosomotropic autophagy inhibitors.
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
Potential Effects of Indomethacin on Alleviating Osteoarthritis Progression in Vitro.
Hydrogen sulfide ameliorated endothelial dysfunction in hyperhomocysteinemia rats: Mechanism of IRE1α/JNK pathway-mediated autophagy.
The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
USP19 Stabilizes TAK1 to Regulate High Glucose/Free Fatty Acid-induced Dysfunction in HK-2 Cells.
CRHR1 antagonist alleviated depression-like behavior by downregulating p62 in a rat model of post-stroke depression.
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
The effect of airborne particulate matter 2.5 (PM(2.5)) on meibomian gland.
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Dexmedetomidine facilitates autophagic flux to promote liver regeneration by suppressing GSK3β activity in mouse partial hepatectomy.
Tanshinone I improves TNBC chemosensitivity by suppressing late-phase autophagy through AKT/p38 MAPK signaling pathway.
Exosomes-mediated transmission of standard bovine viral diarrhea strain OregonC24Va in bovine trophoblast cells.
Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.
A Lipid-Sensitive Spider Peptide Toxin Exhibits Selective Anti-Leukemia Efficacy through Multimodal Mechanisms.
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo.
Antidepressant Sertraline Synergistically Enhances Paclitaxel Efficacy by Inducing Autophagy in Colorectal Cancer Cells.
SIGMAR1 targets AMPK/ULK1 pathway to inhibit SH-SY5Y cell apoptosis by regulating endoplasmic reticulum stress and autophagy.
Baicalin Ameliorates Cartilage Injury in Rats With Osteoarthritis via Modulating miR-766-3p/AIFM1 Axis.
The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.
Magnoflorine attenuates Ang II-induced cardiac remodeling via promoting AMPK-regulated autophagy.
Autophagy-enabled protein degradation: Key to platelet activation and ANGII production in patients with type 2 diabetes mellitus.
Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy.
NLRP4 renders pancreatic cancer resistant to olaparib through promotion of the DNA damage response and ROS-induced autophagy.
The different paradigms of NK cell death in patients with severe trauma.
A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.
A quinolinyl resveratrol derivative alleviates acute ischemic stroke injury by promoting mitophagy for neuroprotection via targeting CK2α'.
Splicing Factor PTBP1 Silencing Induces Apoptosis of Human Cervical Cancer Cells via PI3K/AKT Pathway and Autophagy.
Canagliflozin attenuates post-resuscitation myocardial dysfunction in diabetic rats by inhibiting autophagy through the PI3K/Akt/mTOR pathway.
Mitochondria-Targeted Multifunctional Nanoprodrugs by Inhibiting Metabolic Reprogramming for Combating Cisplatin-Resistant Lung Cancer.
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.
Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signaling.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Programmed cell death 4 blocks autophagy and promotes dopaminergic neuronal injury in Parkinson's disease.
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Tumor cell-derived LC3B(+)extracellular vesicles mediate the crosstalk between tumor microenvironment and immunotherapy efficacy in hepatocellular carcinoma via the HSP90α-IL-6/IL-8 signaling axis.
Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis.
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.
TFEB regulates the odontoblastic differentiation of dental pulp stem cells by promoting a positive feedback loop between mitophagy and glycolysis.
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.
CCCP inhibits DPV infection in DEF cells by attenuating DPV manipulated ROS, apoptosis, and mitochondrial stability.
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells.
PINK1/Park2-Mediated Mitophagy Relieve Non-Alcoholic Fatty Liver Disease.
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Abrogating PDK4 activates autophagy-dependent ferroptosis in breast cancer via ASK1/JNK pathway.
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Magnolol promotes the autophagy of esophageal carcinoma cells by upregulating HACE1 gene expression.
miR-29b-1-5p exacerbates myocardial injury induced by sepsis in a mouse model by targeting TERF2.
Network pharmacology, molecular docking, and in vitro experimental verification of the mechanism of Guanxining in treating diabetic atherosclerosis.
m(1)A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma.
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Tetrandrine alleviates pulmonary fibrosis by inhibiting alveolar epithelial cell senescence through PINK1/Parkin-mediated mitophagy.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Cross-talk between Vimentin and autophagy regulates blood-testis barrier disruption induced by cadmium.
Luteolin and Exercise Combination Therapy Ameliorates Amyloid-β1-42 Oligomers-Induced Cognitive Impairment in AD Mice by Mediating Neuroinflammation and Autophagy.
Bone marrow-derived mesenchymal stem cell-conditioned medium ameliorates diabetic foot ulcers in rats.
Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia.
Effects of perfluorooctane sulfonate (PFOS) on cognitive behavior and autophagy of male mice.
Lidocaine induces neurotoxicity in spinal cord neurons in Goto-Kakizaki rats via AMPK-mediated mitophagy.
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
LAMC2 regulates proliferation, migration, and invasion mediated by the Pl3K/AKT/mTOR pathway in oral.
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction.
Silencing USP19 alleviates cigarette smoke extract-induced mitochondrial dysfunction in BEAS-2B cells by targeting FUNDC1.
Molecular mechanism by which the Notch signaling pathway regulates autophagy in a rat model of pulmonary fibrosis in pigeon breeder's lung.
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling.
Identification of autophagy-related genes in osteoarthritis articular cartilage and their roles in immune infiltration.
Exercise prevents fatal stress-induced myocardial injury in obese mice.
A high-concentrate diet induces inflammatory injury via regulating Ca(2+)/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows.
Exercise improved bone health in aging mice: a role of SIRT1 in regulating autophagy and osteogenic differentiation of BMSCs.
A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth.
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction.
SIRT6 drives sensitivity to ferroptosis in anaplastic thyroid cancer through NCOA4-dependent autophagy.
FBXO5 acts as a novel prognostic biomarker for patients with cervical cancer.
Combined effects of EMP and RF field on emotional behavior in mice.
Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro.
Elevated expression of glycolytic genes as a prominent feature of early-onset preeclampsia: insights from integrative transcriptomic analysis.
Knockdown of ZnT4 Induced Apoptosis, Inhibited Proliferation and testosterone synthesis of TM3 cells.
MIR663AHG as a competitive endogenous RNA regulating TGF-β-induced epithelial proliferation and epithelial-mesenchymal transition in benign prostate hyperplasia.
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Baicalin promotes random-pattern skin flap survival by inducing autophagy via AMPK-regulated TFEB nuclear transcription.
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Pan-cancer integrated bioinformatic analysis of RNA polymerase subunits reveal RNA Pol I member CD3EAP regulates cell growth by modulating autophagy.
CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated mitophagy.
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Spermidine alleviating oxidative stress and apoptosis by inducing autophagy of granulosa cells in Sichuan white geese.
Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis.
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.
Expression Profiles of Long Non-Coding RNAs in the Articular Cartilage of Rats Exposed to T-2 Toxin.
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia.
MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy.
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway.
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney.
Biomimetic Microenvironmental Stiffness Boosts Stemness of Pancreatic Ductal Adenocarcinoma via Augmented Autophagy.
Realgar-Induced Neurotoxicity: Crosstalk Between the Autophagic Flux and the p62-NRF2 Feedback Loop Mediates p62 Accumulation to Promote Apoptosis.
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Edaravone Dexborneol Alleviates Neuroinflammation by Reducing Neuroglial Cell Proliferation and Suppresses Neuronal Apoptosis/Autophagy in Vascular Dementia Rats.
Irisin ameliorates diabetic kidney disease by restoring autophagy in podocytes.
Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species.
Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
The adhesion G protein-coupled receptor VLGR1/ADGRV1 controls autophagy.
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome.
Dexmedetomidine Preconditioning Attenuates Myocardial Ischemia/Reperfusion Injury in Rats by Suppressing Mitophagy Via Activating Α2-Adrenergic Receptor.
Quercetin ameliorates nonalcoholic fatty liver disease (NAFLD) via the promotion of AMPK-mediated hepatic mitophagy.
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
MicroRNA-129-1-3p attenuates autophagy-dependent cell death by targeting MCU in granulosa cells of laying hens under H(2)O(2)-induced oxidative stress.
SERPINB1 promotes Senecavirus A replication by degrading IKBKE and regulating the IFN pathway via autophagy.
Green tea catechin prevents oxidative stress-regulated autophagy and apoptosis signaling, and inhibits tenderness in postmortem bovine longissimus thoracis et lumborum muscle.
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Therapeutic Effect of Prolyl Endopeptidase Inhibitor in High-fat Diet-induced Metabolic Dysfunction-associated Fatty Liver Disease.
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy.
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
[High homocysteine level promotes autophagy and apoptosis of mouse hippocampal HT22 cells through the Notch1/Hes1 signaling pathway].
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR.
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Enhanced Mitophagy in Cholesteatoma Epithelial Cells.
Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway.
Role of SIRT2 in intestinal barrier under cold exposure.
CL4-modified exosomes deliver lncRNA DARS-AS1 siRNA to suppress triple-negative breast cancer progression and attenuate doxorubicin resistance by inhibiting autophagy.
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Grape seed proanthocyanidins regulate mitophagy of endothelial cells and promote wound healing in mice through p-JNK/FOXO3a/ROS signal pathway.
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines.
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway.
circAP1M2 activates ATG9A-associated autophagy by inhibiting miR-1249-3p to promote cisplatin resistance in oral squamous cell carcinoma.
Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway.
Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.
GCN5L1 regulates pulmonary surfactant production by modulating lamellar body biogenesis and trafficking in mouse alveolar epithelial cells.
Matrix stiffness triggers chemoresistance through elevated autophagy in pancreatic ductal adenocarcinoma.
Sulforaphane ameliorated podocyte injury according to regulation of the Nrf2/PINK1 pathway for mitophagy in diabetic kidney disease.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination.
Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway.
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma.
High-intensity interval training alleviates exhaustive exercise-induced HSP70-assisted selective autophagy in skeletal muscle.
DJ1 Ameliorates AD-like Pathology in the Hippocampus of APP/PS1 Mice.
IL-17A promotes tumorigenesis and upregulates PD-L1 expression in non-small cell lung cancer.
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
RNA m(6)A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis.
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
CAB39 promotes cisplatin resistance in bladder cancer via the LKB1-AMPK-LC3 pathway.
Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles.
Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair.
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.
Follicular fluid exosomes regulate OVGP1 secretion in yak oviduct epithelial cells via autophagy in vitro.
Zinc-Deficient Diet Causes Imbalance in Zinc Homeostasis and Impaired Autophagy and Impairs Semen Quality in Mice.
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy.
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Rosuvastatin promotes survival of random skin flaps through AMPK-mTOR pathway-induced autophagy.
Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Anticancer efficacy of hirsuteine against colorectal cancer by opposite modulation of wild-type and mutant p53.
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis.
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Treponema pallidum membrane protein Tp47 promotes angiogenesis through ROS-induced autophagy.
Inhibition of PI3K/Akt/mTOR signaling by NDRG2 contributes to neuronal apoptosis and autophagy in ischemic stroke.
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy.
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Subacute ruminal acidosis downregulates FOXA2, changes oxidative status, and induces autophagy in the livers of dairy cows fed a high-concentrate diet.
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis.
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
PSMD2 contributes to the progression of esophageal squamous cell carcinoma by repressing autophagy.
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Collateral activity of the CRISPR/RfxCas13d system in human cells.
The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells.
Hypothermic Oxygenated Machine Perfusion Promotes Mitophagy Flux against Hypoxia-Ischemic Injury in Rat DCD Liver.
Electroacupuncture repairs intestinal barrier by upregulating CB1 through gut microbiota in DSS-induced acute colitis.
Pre-ischaemic Treatment with Enriched Environment Alleviates Acute Neuronal Injury by Inhibiting Endoplasmic Reticulum Stress-dependent Autophagy and Apoptosis.
m(6)A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
Role of histone deacetylase 9 in human periodontal ligament stem cells autophagy in a tumour necrosis factor α-induced inflammatory environment.
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury via inhibiting autophagy through PI3K/Akt/mTOR pathway.
Ursolic acid nanoparticles for glioblastoma therapy.
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Protective Effect and Mechanism of Kuntai Capsule on Angiotensin II -Induced Hypertension in Ovariectomized Rats.
Robo2 promotes osteoblast differentiation and mineralization through autophagy and is activated by parathyroid hormone induction.
Immunostimulation with chemotherapy of a ruthenium-arene complex via blockading CD47 signal in chronic myelogenous leukemia cells.
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection.
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma.
Tailor-Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Time-dependent effect of REV-ERBα agonist SR9009 on nonalcoholic steatohepatitis and gut microbiota in mice.
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
ATB(0,+)-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Scalp acupuncture alleviates cerebral ischemic stroke-induced motor dysfunction in rats via regulating endoplasmic reticulum stress and ER-phagy.
Microcystin-LR-Exposure-Induced Kidney Damage by Inhibiting MKK6-Mediated Mitophagy in Mice.
Mannose-Binding Lectin Reduces Oxidized Low-Density Lipoprotein Induced Vascular Endothelial Cells Injury by Inhibiting LOX1-ox-LDL Binding and Modulating Autophagy.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
Bioengineered Nanospores Selectively Blocking LC3-Associated Phagocytosis in Tumor-Associated Macrophages Potentiate Antitumor Immunity.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs.
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Analgesic Effect of Perineural Injection of BoNT/A on Neuropathic Pain Induced by Chronic Constriction Injury of Sciatic Nerve in Rats.
Bavachin protects against diet-induced hepatic steatosis and obesity in mice.
HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death.
Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
GPRC5B protects osteoarthritis by regulation of autophagy signaling.
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
New fungal protein from Pleurotus ferulae lanzi induces AMPK-mediated autophagy and G1-phase cell cycle arrest in A549 lung cancer cells.
PTEN Overexpression Alters Autophagy Levels and Slows Sodium Arsenite-Induced Hepatic Stellate Cell Fibrosis.
Cold exposure protects against medial arterial calcification development via autophagy.
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
Mitochondrial pyruvate carrier 1 alleviates hypoxic-ischemic brain injury in rats.
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lysophosphatidic acid is associated with oocyte maturation by enhancing autophagy via PI3K-AKT-mTOR signaling pathway in granulosa cells.
Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells.
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice.
Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents.
Denosumab Can Prevent Collapse in Patients with Early-Stage Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy.
Berberine enhances autophagic flux by activating the Nrf2 signaling pathway in bovine endometrial epithelial cells to resist LPS-induced apoptosis.
Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1.
Long-term copper exposure caused hepatocytes autophagy in broiler via miR-455-3p-OXSR1 axis.
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Effects of exogenous spermidine on autophagy and antioxidant capacity in ovaries and granulosa cells of Sichuan white geese.
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae in Apis mellifera.
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Autophagy induced by Rab1a-ULK1 interaction promotes porcine reproductive and respiratory syndrome virus replication.
Newly identified lncRNA-45 promotes breast cancer metastasis through activating the mTOR signaling pathway.
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway.
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer.
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway.
RBM3 interacts with Raptor to regulate autophagy and protect cardiomyocytes from ischemia-reperfusion-induced injury.
Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival.
The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Strontium ion attenuates osteoarthritis through inhibiting senescence and enhancing autophagy in fibroblast-like synoviocytes.
DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC.
Chloroquine is a safe autophagy inhibitor for sustaining the expression of antioxidant enzymes in trophoblasts.
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM Pathway.
Autophagy-Related Gene WD Repeat Domain 45B Promotes Tumor Proliferation and Migration of Hepatocellular Carcinoma through the Akt/mTOR Signaling Pathway.
Osteogenic effects of rapamycin on bone marrow mesenchymal stem cells via inducing autophagy.
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Metformin regulates autophagy via LGMN to inhibit choriocarcinoma.
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling.
Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways.
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways.
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis.
Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity.
Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma.
Activation of moderate autophagy promotes survival of fat graft.
Ame-miR-980-3p participates in autophagy-mediated midgut remodelling in Apis mellifera via targeting Atg2B.
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway.
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Ginsenoside Rb2 improves heart failure by down-regulating miR-216a-5p to promote autophagy and inhibit apoptosis and oxidative stress.
Exogenous H(2)S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice.
ZnO nanoparticles impair autophagic flux and cell viability through the TRIM16-NRF2-p62 pathway in inflammatory keratinocytes.
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway.
Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells.
Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
COPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy.
The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication.
Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats.
Targeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer.
Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis.
Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
Quantitative transcriptomic and proteomic analysis reveals corosolic acid inhibiting bladder cancer via suppressing cell cycle and inducing mitophagy in vitro and in vivo.
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
Temporal Dynamic Regulation of Autophagy and Senescence Induction in Response to Radiation Exposure.
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy.
The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP.
Nanozyme-Integrated Thermoresponsive In Situ Forming Hydrogel Enhances Mesenchymal Stem Cell Viability and Paracrine Effect for Efficient Spinal Cord Repair.
Interaction of L1CAM with LC3 Is Required for L1-Dependent Neurite Outgrowth and Neuronal Survival.
Curcumin in vitro Neuroprotective Effects Are Mediated by p62/keap-1/Nrf2 and PI3K/AKT Signaling Pathway and Autophagy Inhibition.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy.
Sarmentosin Induces Autophagy-dependent Apoptosis via Activation of Nrf2 in Hepatocellular Carcinoma.
α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis.
Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways.
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.
Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity.
Nrf2 protects against methamphetamine-induced nephrotoxicity by mitigating oxidative stress and autophagy in mice.
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease.
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease.
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway.
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
Abamectin causes toxicity to the carp respiratory system by triggering oxidative stress, inflammation, and apoptosis and inhibiting autophagy.
ETNPPL impairs autophagy through regulation of the ARG2-ROS signaling axis, contributing to palmitic acid-induced hepatic insulin resistance.
Crosstalk between Mfn2-mediated mitochondria associated membranes disorder and autophagy induced by molybdenum and cadmium in sheep heart.
Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway.
Mesenchymal stromal cells ameliorate diabetes-induced muscle atrophy through exosomes by enhancing AMPK/ULK1-mediated autophagy.
A Novel Tri-Functional Liposome Re-Educates "Cold Tumor" and Abrogates Tumor Growth by Synergizing Autophagy Inhibition and PD-L1 Blockade.
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy.
Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.
HCMV-encoded viral protein US12 promotes autophagy by inducing autophagy flux.
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Blue LED light induces cytotoxicity via ROS production and mitochondrial damage in bovine subcutaneous preadipocytes.
Dysregulated autophagy-related genes in septic cardiomyopathy: Comprehensive bioinformatics analysis based on the human transcriptomes and experimental validation.
The KLF4-p62 axis prevents vascular endothelial cell injury via the mTOR/S6K pathway and autophagy in diabetic kidney disease.
Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy.
BRD4 Inhibition Suppresses Senescence and Apoptosis of Nucleus Pulposus Cells by Inducing Autophagy during Intervertebral Disc Degeneration: An In Vitro and In Vivo Study.
Resveratrol Synergistically Promotes BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells.
Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells.
Artemisinin Alleviates Cerebral Ischemia/Reperfusion-Induced Oxidative Damage via Regulating PHB2-Mediated Autophagy in the Human Neuroblastoma SH-SY5Y Cell Line.
Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway.
Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway.
SIRT2 Affects Cell Proliferation and Apoptosis by Suppressing the Level of Autophagy in Renal Podocytes.
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway.
The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease.
Beclin1 Deficiency Suppresses Epileptic Seizures.
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity.
Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy.
LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2.
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.
Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway.
Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma.
Src Activation Aggravates Podocyte Injury in Diabetic Nephropathy via Suppression of FUNDC1-Mediated Mitophagy.
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Melatonin alleviates renal injury by activating mitophagy in diabetic nephropathy.
Protocatechualdehyde Rescues Oxygen-Glucose Deprivation/Reoxygenation-Induced Endothelial Cells Injury by Inducing Autophagy and Inhibiting Apoptosis via Regulation of SIRT1.
TMT-Based Quantitative Proteomics Analysis Reveals the Panoramic Pharmacological Molecular Mechanism of β-Elemonic Acid Inhibition of Colorectal Cancer.
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment.
Transcriptome Analysis Reveal Candidate Genes and Pathways Responses to Lactate Dehydrogenase Inhibition (Oxamate) in Hyperglycemic Human Renal Proximal Epithelial Tubular Cells.
Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats.
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting.
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.
Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus.
Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.
Mycoplasma hyopneumoniae Infection Activates the NOD1 Signaling Pathway to Modulate Inflammation.
Cathepsin B plays a role in spermatogenesis and sperm maturation through regulating autophagy and apoptosis in mice.
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Comprehensive Analysis of Quantitative Proteomics With DIA Mass Spectrometry and ceRNA Network in Intrahepatic Cholestasis of Pregnancy.
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
Ferulic acid ameliorates acetaminophen-induced acute liver injury by promoting AMPK-mediated protective autophagy.
Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway.
Gold nanoparticles targeting the autophagy-lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: From mechanism to therapy.
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
Propofol inhibits the malignant development of osteosarcoma U2OS cells via AMPK/FΟΧO1-mediated autophagy.
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis.
Ferulic acid ameliorates renal injury via improving autophagy to inhibit inflammation in diabetic nephropathy mice.
Long non-coding RNA IGFBP7-AS1 promotes odontogenic differentiation of stem cells from human exfoliated deciduous teeth through autophagy: An in vitro study.
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
Sodium butyrate attenuates bovine mammary epithelial cell injury by inhibiting the formation of neutrophil extracellular traps.
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Achyranthoside D (AD) improve intervertebral disc degeneration through affect the autophagy and the activation of PI3K/Akt/mTOR pathway.
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway.
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle.
Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis.
Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway.
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
Puerarin prevents calcium oxalate crystal-induced renal epithelial cell autophagy by activating the SIRT1-mediated signaling pathway.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
ROS function as an inducer of autophagy to promote granulocyte proliferation in Pacific oyster Crassostrea gigas.
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Haizao Yuhu decoctions including three species of glycyrrhiza protected against propylthiouracil-induced goiter with hypothyroidism in rats via the AMPK/mTOR pathway.
Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
Nobiletin mitigates NAFLD via lipophagy and inflammation.
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.
MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy.
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Rab11a promotes the malignant progression of ovarian cancer by inducing autophagy.
Tp47 promoted the phagocytosis of HMC3 cells though autophagy induced by endoplamic reticlum stress.
Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation.
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Effect of rapamycin treatment on oocyte in vitro maturation and embryonic development after parthenogenesis in yaks.
Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells.
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Paeoniflorin binds to VEGFR2 to restore autophagy and inhibit apoptosis for podocyte protection in diabetic kidney disease through PI3K-AKT signaling pathway.
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Long-Term Consumption of Food-Derived Chlorogenic Acid Protects Mice against Acetaminophen-Induced Hepatotoxicity via Promoting PINK1-Dependent Mitophagy and Inhibiting Apoptosis.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Moderate Treadmill Exercise Alleviates NAFLD by Regulating the Biogenesis and Autophagy of Lipid Droplet.
Trpc5-regulated AMPKα/mTOR autophagy pathway is associated with glucose metabolism disorders in low birth weight mice under overnutrition.
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance.
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Dihydromyricetin protects against Doxorubicin-induced cardiotoxicity through activation of AMPK/mTOR pathway.
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.
Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Paired related homeobox 1 attenuates autophagy via acetyl-CoA carboxylase 1-regulated fatty acid metabolism in salivary adenoid cystic carcinoma.
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Quercus acutissima Carruth. root extract triggers apoptosis, autophagy and inhibits cell viability in breast cancer cells.
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes.
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Evaluation of BPA effects on autophagy in Neuro-2a cells.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
CN-3 increases TMZ sensitivity and induces ROS-dependent apoptosis and autophagy in TMZ-resistance glioblastoma.
Vitamin D3 promotes autophagy in THP-1 cells infected with Mycobacterium tuberculosis.
miR-146a-5p/TXNIP axis attenuates intestinal ischemia-reperfusion injury by inhibiting autophagy via the PRKAA/mTOR signaling pathway.
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Bcl-2 interacting protein 3 (BNIP3) promotes tumor growth in breast cancer under hypoxic conditions through an autophagy-dependent pathway.
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cells.
Genome-wide CRISPR/Cas9 screen identifies host factors important for porcine reproductive and respiratory syndrome virus replication.
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma.
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat.
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis.
Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids.
Clinical, genetic, and pathological characterization of GNE myopathy in China.
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure.
Autism spectrum disorder-like behavior induced in rat offspring by perinatal exposure to di-(2-ethylhexyl) phthalate.
The cardiotoxicity of asthmatic rats after traffic-related PM(2.5) and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy.
TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy.
Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy.
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
3,4,5-O-tricaffeoylquinic acid with anti-radiation activity suppresses LPS-induced NLRP3 inflammasome activation via autophagy in THP-1 macrophages.
Multifunctional theranostic nanoplatform loaded with autophagy inhibitor for enhanced photothermal cancer therapy under mild near-infrared irradiation.
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Resveratrol alleviates enterotoxigenic Escherichia coli K88-induced damage by regulating SIRT-1 signaling in intestinal porcine epithelial cells.
Gga-miR-30c-5p Suppresses Avian Reovirus (ARV) Replication by Inhibition of ARV-Induced Autophagy via Targeting ATG5.
MiR-152-5p suppresses osteogenic differentiation of mandible mesenchymal stem cells by regulating ATG14-mediated autophagy.
T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells.
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis.
FUNDC1-mediated mitophagy and HIF1α activation drives pulmonary hypertension during hypoxia.
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Rosa rugosa polysaccharide induces autophagy-mediated apoptosis in human cervical cancer cells via the PI3K/AKT/mTOR pathway.
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma.
Lycorine improves peripheral nerve function by promoting Schwann cell autophagy via AMPK pathway activation and MMP9 downregulation in diabetic peripheral neuropathy.
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy.
Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma.
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Imiquimod induced vitiligo-like lesions-A consequence of modified melanocyte function.
Mitochondrial dysfunction is involved in the cellular activity inhibition by eleutheroside B in SMMC-7721 and HeLa cells.
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Host Restriction Factor A3G Inhibits the Replication of Enterovirus D68 by Competitively Binding the 5' Untranslated Region with PCBP1.
Structural Variability of Lipoarabinomannan Modulates Innate Immune Responses within Infected Alveolar Epithelial Cells.
Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway.
C9orf72 knockdown alleviates hepatic insulin resistance by promoting lipophagy.
Biotinylated curcumin as a novel chemosensitizer enhances naphthalimide-induced autophagic cell death in breast cancer cells.
Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy.
RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM).
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner.
Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice.
Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis rats by inhibiting Th1/Th17 immune responses.
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
Levosimendan protects from sepsis-inducing cardiac dysfunction by suppressing inflammation, oxidative stress and regulating cardiac mitophagy via the PINK-1-Parkin pathway in mice.
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice.
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas.
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Tryptophan-sorbitol based carbon quantum dots for theranostics against hepatocellular carcinoma.
RNA sequence analysis reveals pathways and candidate genes associated with pancreatic acinar cells injury in a mouse pancreatitis model.
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis.
LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma.
The SMYD3-MTHFD1L-formate metabolic regulatory axis mediates mitophagy to inhibit M1 polarization in macrophages.
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Sulforaphane Ameliorates Hepatic Lipid Metabolism via Modulating Lipophagy In Vivo and In Vitro.
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
HIF-1α-mediated autophagy and canonical Wnt/β-catenin signalling activation are involved in fluoride-induced osteosclerosis in rats.
Lactoferrin alleviates spermatogenesis dysfunction caused by bisphenol A and cadmium via ameliorating disordered autophagy, apoptosis and oxidative stress.
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress.
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Dietary supplementation with metformin improves testis function and semen quality and increases antioxidants and autophagy capacity in goats.
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Inhibition of autophagy by 3-methyladenine promotes migration and invasion of colon cancer cells through epithelial mesenchymal transformation.
Comprehensive analysis of placental gene-expression profiles and identification of EGFR-mediated autophagy and ferroptosis suppression in intrahepatic cholestasis of pregnancy.
CHST7 Methylation Status Related to the Proliferation and Differentiation of Pituitary Adenomas.
Hyaluronic Acid Oligosaccharide Derivatives Alleviate Lipopolysaccharide-Induced Inflammation in ATDC5 Cells by Multiple Mechanisms.
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Sesamin Ameliorates Fine Particulate Matter (PM(2.5))-Induced Lung Injury via Suppression of Apoptosis and Autophagy in Rats.
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Autophagy: A New Mechanism for Esketamine as a Depression Therapeutic.
Arsenic Prodrug-Mediated Tumor Microenvironment Modulation Platform for Synergetic Glioblastoma Therapy.
Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy.
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10.
Autophagic degradation of claudin-5 mediated by its binding to a Clostridium perfringens enterotoxin fragment modulates endothelial barrier permeability.
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Apelin-13/APJ induces cardiomyocyte hypertrophy by activating the Pannexin-1/P2X7 axis and FAM134B-dependent reticulophagy.
All-In-One Biomimetic Nanoplatform Based on Hollow Polydopamine Nanoparticles for Synergistically Enhanced Radiotherapy of Colon Cancer.
MOXD1 knockdown suppresses the proliferation and tumor growth of glioblastoma cells via ER stress-inducing apoptosis.
Interpreting the Pharmacological Mechanisms of Sho-saiko-to on Thyroid Carcinoma through Combining Network Pharmacology and Experimental Evaluation.
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
HMGB1-mediated autophagy promotes gefitinib resistance in human non-small cell lung cancer.
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway.
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction.
CHNQD-00603 Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by the miR-452-3p-Mediated Autophagy Pathway.
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway.
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration.
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice.
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Effect of Vitamin D Deficiency and Supplementation in Lactation and Early Life on Allergic Airway Inflammation and the Expression of Autophagy-Related Genes in an Ovalbumin Mouse Model.
Effect of GLUT1 Inhibition and Autophagy Modulation on the Growth and Migration of Laryngeal Carcinoma Stem Cells Under Hypoxic and Low-Glucose Conditions.
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy.
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Delivery of siRNA Using Functionalized Gold Nanorods Enhances Anti-Osteosarcoma Efficacy.
Curcumin is a Potential Adjuvant to Alleviates Diabetic Retinal Injury via Reducing Oxidative Stress and Maintaining Nrf2 Pathway Homeostasis.
Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells.
The Disulfiram/Copper Complex Induces Autophagic Cell Death in Colorectal Cancer by Targeting ULK1.
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats.
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.
Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway.
Compensatory combination of mTOR and TrxR inhibitors to cause oxidative stress and regression of tumors.
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells.
Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.
Decreased neuronal synaptosome associated protein 29 contributes to poststroke cognitive impairment by disrupting presynaptic maintenance.
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Circular RNA TRAPPC6B inhibits intracellular Mycobacterium tuberculosis growth while inducing autophagy in macrophages by targeting microRNA-874-3p.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
The enhancement of Tetrandrine to gemcitabine-resistant PANC-1 cytochemical sensitivity involves the promotion of PI3K/Akt/mTOR-mediated apoptosis and AMPK-regulated autophagy.
Biofunctional magnesium-coated Ti6Al4V scaffolds promote autophagy-dependent apoptosis in osteosarcoma by activating the AMPK/mTOR/ULK1 signaling pathway.
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
A Marine λ-Oligocarrageenan Inhibits Migratory and Invasive Ability of MDA-MB-231 Human Breast Cancer Cells through Actions on Heparanase Metabolism and MMP-14/MMP-2 Axis.
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway.
Inhibition of endoplasmic reticulum stress-related autophagy attenuates MCLR-induced apoptosis in zebrafish testis and mouse TM4 cells.
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy.
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218.
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.
ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Co-modification with MSC membrane and PDA prevents Fe(3)O(4)-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy.
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Liquiritigenin protects against arsenic trioxide-induced liver injury by inhibiting oxidative stress and enhancing mTOR-mediated autophagy.
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia.
Long non-coding RNA LINC01559 exerts oncogenic role via enhancing autophagy in lung adenocarcinoma.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy.
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
Hepatic COX-2 expression protects mice from an alcohol-high fat diet-induced metabolic disorder by involving protein acetylation related energy metabolism.
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
17β-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events.
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
The nicotinamide phosphoribosyltransferase antagonist FK866 inhibits growth of prostate tumour spheroids and increases doxorubicin retention without changes in drug transporter and cancer stem cell protein expression.
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src.
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation.
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Oroxylin A is a severe acute respiratory syndrome coronavirus 2-spiked pseudotyped virus blocker obtained from Radix Scutellariae using angiotensin-converting enzyme II/cell membrane chromatography.
Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy.
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Study on the anti-hepatocarcinoma effect and molecular mechanism of Prunella vulgaris total flavonoids.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
The Difference in Expression of Autophagy-Related Proteins in Lesional and Perilesional Skin in Adult Patients with Active and Stable Generalized Vitiligo-A Cross-Sectional Pilot Study.
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Pharmacological activation of REV-ERBα improves nonalcoholic steatohepatitis by regulating intestinal permeability.
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Atmospheric PM(2.5) blocking up autophagic flux in HUVECs via inhibiting Sntaxin-17 and LAMP2.
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Cholecalciferol (vitamin D(3)) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes.
Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities.
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway.
The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells.
Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway.
Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways.
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy.
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2).
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Alleviation of CCCP-induced mitochondrial injury by augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy.
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Atorvastatin reverses high cholesterol-induced cardiac remodelling and regulates mitochondrial quality-control in a cholesterol-independent manner: An experimental study.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
CIDEC silencing attenuates diabetic nephropathy via inhibiting apoptosis and promoting autophagy.
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish.
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis.
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway.
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis.
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis.
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells.
Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation.
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes.
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Morroniside Inhibits H(2)O(2)-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells.
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling.
LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes.
Autophagy Is a Potential Therapeutic Target Against Duck Tembusu Virus Infection in vivo.
Effect of combination of curcumin and GLUT-1 AS-ODN on radiosensitivity of laryngeal carcinoma through regulating autophagy.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
A lysosome-targeted ruthenium(II) polypyridyl complex as photodynamic anticancer agent.
A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma.
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Globular CTRP9 protects cardiomyocytes from palmitic acid-induced oxidative stress by enhancing autophagic flux.
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
Cellular evidence of autophagy in Sertoli cells during spermatogenesis in goats.
Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway.
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway.
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level.
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C.
Inhibiting PKCβ2 protects HK-2 cells against meglumine diatrizoate and AGEs-induced apoptosis and autophagy.
Autophagy in endothelial cells regulates their haematopoiesis-supporting ability.
Autophagy and Hsp70 activation alleviate oral epithelial cell death induced by food-derived hypertonicity.
Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition.
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
NeuroHeal Treatment Alleviates Neuropathic Pain and Enhances Sensory Axon Regeneration.
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro.
Calcitriol decreases live Porphyromonas gingivalis internalized into epithelial cells and monocytes by promoting autophagy.
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
The Effect of Autophagic Activity on the Function of Apheresis Platelets and on the Efficacy of Clinical Platelet Transfusion.
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway.
Aldehyde dehydrogenase 2 regulates autophagy via the Akt-mTOR pathway to mitigate renal ischemia-reperfusion injury in hypothermic machine perfusion.
Methylmercury disrupts autophagic flux by inhibiting autophagosome-lysosome fusion in mouse germ cells.
Melatonin alleviates defects induced by zearalenone during porcine embryo development.
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Cells deficient for Krüppel-like factor 4 exhibit mitochondrial dysfunction and impaired mitophagy.
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
14-3-3ζ binds to and stabilizes phospho-beclin 1(S295) and induces autophagy in hepatocellular carcinoma cells.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro.
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway.
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.
Potential therapeutic role of fibroblast growth factor 21 in neurodegeneration: Evidence for ameliorating parkinsonism via silent information regulator 2 homolog 1 and implication for gene therapy.
CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway.
Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes.
Toll-Like Receptor 2-Mediated Autophagy Promotes Microglial Cell Death by Modulating the Microglial M1/M2 Phenotype.
Organic anion transporters and PI3K-AKT-mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein.
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis.
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis.
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA.
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Leucine-rich repeat and sterile alpha motif containing 1 promotes the oncogenic growth of human hepatocellular carcinoma cells.
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Transmembrane Protein 39A Promotes the Replication of Encephalomyocarditis Virus via Autophagy Pathway.
Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Rapamycin attenuates articular cartilage degeneration by inhibiting β-catenin in a murine model of osteoarthritis.
Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice.
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Orientin Improves Cognition by Enhancing Autophagosome Clearance in an Alzheimer's Mouse Model.
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma.
Enhancing autophagy by down-regulating GSK-3β alleviates cisplatin-induced ototoxicity in vivo and in vitro.
B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Fibroblast growth factor-21 alleviates hypoxia/reoxygenation injury in H9c2 cardiomyocytes by promoting autophagic flux.
Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy.
2,3',4,4',5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway.
Drp1-associated mitochondrial dysfunction and mitochondrial autophagy: a novel mechanism in triptolide-induced hepatotoxicity.
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
MicroRNA-101 regulates autophagy, proliferation and apoptosis via targeting EZH2 in laryngeal squamous cell carcinoma.
Exogenous hydrogen sulfide mitigates NLRP3 inflammasome-mediated inflammation through promoting autophagy via the AMPK-mTOR pathway.
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells.
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Microglia as modulators of exosomal alpha-synuclein transmission.
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.
Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2.
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Conditioned medium obtained from human amniotic mesenchymal stem cells attenuates focal cerebral ischemia/reperfusion injury in rats by targeting mTOR pathway.
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice.
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
Hexabromocyclododecanes promoted autophagy through the PI3K/Akt/mTOR pathway in L02 cells.
Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells.
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Silver nanoparticles induce protective autophagy via Ca(2+)/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
β-Arrestin2 Inhibits Expression of Inflammatory Cytokines in BEAS-2B Lung Epithelial Cells Treated with Cigarette Smoke Condensate via Inhibition of Autophagy.
Xiaoqinglong Decoction Attenuates Chronic Obstructive Pulmonary Disease in Rats via Inhibition of Autophagy.
Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation.
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma.
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells.
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins.
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Mutant UBQLN2(P497H) in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Peroxisome Proliferator-Activated Receptor (PPARγ) Plays a Protective Role in Cigarette Smoking-Induced Inflammation via AMP-Activated Protein Kinase (AMPK) Signaling.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Autophagy participates in innate immune defense in lamprey.
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer.
Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice.
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Interplay of Autophagy Inducer Rapamycin and Proteasome Inhibitor MG132 in Reduction of Foam Cell Formation and Inflammatory Cytokine Expression.
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.
Autophagy is required for proper meiosis of porcine oocytes maturing in vitro.
Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway.
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Resveratrol prevents the combined maternal plus postweaning high-fat-diets-induced hypertension in male offspring.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer.
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells.
Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy.
Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells.
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis.
Cheng A, Wu Y, Luo H, Song X, Li X, Fan B, Zhang X, Liu S, Zhuang C, Zhao Y, Wang J, Liang C, Liang B, Zhang J
Research (Washington, D.C.) 2026;9:1113
Research (Washington, D.C.) 2026;9:1113
A Novel Autophagy Inhibitor p-Hydroxylcinnamaldehyde Suppresses Esophageal Squamous Cell Carcinoma by Targeting LDHA Phosphorylation-Mediated Metabolic Reprogramming.
Wei S, Wang J, Zhang Z, Fu Y, Zhao L, Bi Y, Li X, Dai S, Zhang C, Zhu W, Min L, Shan B, Zhao L
Research (Washington, D.C.) 2026;9:1070
Research (Washington, D.C.) 2026;9:1070
p62 limits Salmonella Typhimurium in macrophages through its role in cell signalling.
Underwood D, Balci A, Solano-Collado V, Wilson HM, Baldassarre M, Spanò S
Access microbiology 2026;8(1)
Access microbiology 2026;8(1)
Monitoring Autophagosome Biogenesis and Degradation in Mammalian Cells Using LC3B Blotting.
Palmer JE, Rubinsztein DC
Methods in molecular biology (Clifton, N.J.) 2026;2976:47-60
Methods in molecular biology (Clifton, N.J.) 2026;2976:47-60
Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Gong K, Song K, Wang H, Li L, Sun X, Sun L, Hao W, Chen ZS, Huang Y
International journal of biological sciences 2026;22(5):2215-2232
International journal of biological sciences 2026;22(5):2215-2232
SIRT6-Mediated Regulation of TFAM: A Central Mechanism Connecting Nuclear and Mitochondrial Transcriptional Processes and Mitophagy.
Jiang M, Li J, Ding N, Jia G, Wu S, Liu N, Kang Y, Zhang G, Wu J, Zhang L, Zhang Y
International journal of biological sciences 2026;22(1):178-200
International journal of biological sciences 2026;22(1):178-200
ATG7 vs. ATG5: Distinct autophagy pathways shaping TGF-β signaling and endothelial function.
Singh A, Peddi B, Bhatt KS, Nguyen HC, Singh KK
PloS one 2026;21(4):e0335584
PloS one 2026;21(4):e0335584
Aspergillus fumigatus Gliotoxin Inhibits LC3-Associated Phagocytosis in Macrophages in a Calcium-Dependent Manner.
Sun Y, Chen F, Zhang L, Zheng C, Wang Y, Zhang Y, Han L
Journal of immunology research 2026;2026(1):e5542735
Journal of immunology research 2026;2026(1):e5542735
Quercetin regulates autophagy and attenuates airway inflammation in a murine model of asthma: association with PI3K/Akt/mTOR signaling pathway modulation.
Lang L, Liu S, Zhang W, Zhang J, Liu H
Frontiers in pharmacology 2026;17:1755094
Frontiers in pharmacology 2026;17:1755094
Arsenic trioxide-induced acute kidney injury: OPA1- and Drp1-mediated mitochondrial dynamics imbalance, PINK1/Parkin-dependent mitophagy, and Chuanhuang Fang III.
Wang P, Wu Z, Song Z, Deng X, Zhang Y, Gong X
Frontiers in molecular biosciences 2026;13:1778855
Frontiers in molecular biosciences 2026;13:1778855
Nanosized silicon nitride promotes vascularized osteogenesis through regulating the endothelial adherens junctions via the FRMD6/VE-cadherin pathway.
Wang R, Liu Z, Liu W, Zheng X, Zhao Y, Huang F, Wen S, Gan Y, Huang Z, Zhang Y, Lu Y, Rong M
Biomaterials 2026 Sep;332:124150
Biomaterials 2026 Sep;332:124150
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
Li Z, Ma Z, Chen Y, Yu W, Yu J, Lu J, Zhang Q, Wu Q, Cai Y, Wang Z, Shang C, Hou B, Zhang C, Huang S, Wang L, Zhou Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
Quercetin attenuates tendon stem/progenitor cell senescence and promotes aged tendon repair via AKT/NF-κB/NLRP3-mediated mitophagy activation.
Wang H, Gao YC, Ming-Zhang, Dai GC, Lu PP, Li YJ, Cao MM, Liu XY, Sheng RW, Shi L, Zhang C, Cui WG, Rui YF
Journal of advanced research 2026 May;83:741-758
Journal of advanced research 2026 May;83:741-758
Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
Lu Z, Zhou H, Tang H, Luo S, Wang J, Zheng X, Hu Y, Qin Q, Yang C, Mo S, Huang X, Tang L, Huang B, Xu W, Nong J, Gan G, Qin D, Peng Z, Jian C, Liu X, Li X, Shang J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
Astragalus membranaceus Polysaccharides Attenuate Osteoarthritis in Human Primary Chondrocytes and in Animal Model: Mechanism Study Using RNA-Seq and Network Pharmacology.
Xu H, Li Y, Wang J, Xin Y, Xu Q, Qin X, Yang X, Yan Y, Chen Q, Chen Y, Zhang Y, Lu C, Xu K, Wang X
Phytotherapy research : PTR 2026 May;40(5):2249-2269
Phytotherapy research : PTR 2026 May;40(5):2249-2269
Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.
Zhu T, Jiao X, Shi J, Wang B, Li C, Li Y
Veterinary microbiology 2026 May;316:110993
Veterinary microbiology 2026 May;316:110993
Maresin 1 activates autophagy through SIRT1/PPAR-γ signaling to mitigate high glucose-induced pyroptosis in human retinal pigment epithelial cells.
Zhang J, Zhao D, Zhang Y, Sun H, Yan Z, Sun H
Experimental and therapeutic medicine 2026 May;31(5):141
Experimental and therapeutic medicine 2026 May;31(5):141
Schisandrin B enhances autophagy and random flaps survival through the PPARG-mediated PI3K/AKT/mTOR signaling pathway.
Li Y, Zhang J, Yang J, Gao J, Jin Y, Zhang Y, Chen H, Cai L
Free radical biology & medicine 2026 May;248:92-108
Free radical biology & medicine 2026 May;248:92-108
Detoxification of T-2 toxin in human chondrocytes due to its hydroxylation by carboxylesterases and arylacetamide deacetylase in the liver.
Cheng S, Shi S, Cheng B, Liu C, Yang X, Liu L, Liu H, Wen Y, Tinkov AA, Skalny AV, Jia Y, Zhang F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:116007
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 May;211:116007
vtRNA1-1/p62 regulates macrophages autophagy in ankylosing spondylitis.
Jiang M, Ni J, Yu X, Zhao H, Lu X, Cheng L, Li Z, Wu H, Pan Z, Qu L, Gao M, Cai G, Wang M, Pan F
Molecular immunology 2026 May;193:1-9
Molecular immunology 2026 May;193:1-9
High-fat diet perturbs hepatic lipid metabolism and impairs colonic autophagy to exacerbate experimental colitis.
Xu T, Shi J, Ji J, Ma C, Li J
3 Biotech 2026 May;16(5):171
3 Biotech 2026 May;16(5):171
Ginsenoside Rg1 mitigates sepsis-associated acute respiratory distress syndrome by promoting autophagy through the Prdx1-PTEN/PI3K/AKT pathway.
Xue X, Huang C, Chen J, Ding W, Ren Y, Zhang W, Li Q, Yang Z, Sun Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158027
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158027
PGC-1α exacerbates apoptosis to induce HIF-1α/BNIP3 mediated mitophagy in heart failure.
Ni C, Hu P, Ni Y
Biochemical and biophysical research communications 2026 May 7;812:153592
Biochemical and biophysical research communications 2026 May 7;812:153592
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.
Basili I, Bufalieri F, Conenna M, Navacci S, Li YR, Torrejon J, Bernardi F, Lospinoso Severini L, Marsaud V, Cancila G, Bourmeau G, Yu H, Lo Re V, Talbot J, Adabbo G, Di Pinto A, Agnoli F, Giovannini D, Leonardi S, Bordone R, Petroni M, Souphron J, Blauwblomme T, Beccaria K, Dufour C, D'Angelo L, De Smaele E, Canettieri G, Giannini G, Fimia GM, Maroder M, Guardavaccaro D, Pazzaglia S, Tsai JW, Infante P, Ayrault O, Di Marcotullio L
Developmental cell 2026 May 13;61(5):1111-1126.e9
Developmental cell 2026 May 13;61(5):1111-1126.e9
Grape Seed Proanthocyanins Extract Ameliorates the Neurotoxicity Induced by Fluoride Through mTOR/p70s6k Signaling Pathway in Vivo and in Vitro.
Zhao W, Gong Z, Wang B, Wu Z, Guo Y, Wang S, Zhai H, Zheng X, Yang L
Cell biochemistry and biophysics 2026 Mar;84(1):967-983
Cell biochemistry and biophysics 2026 Mar;84(1):967-983
Stattic engineering M2 macrophage-derived exosomes mediate autophagy and immune reprogramming for secondary hyperparathyroidism.
Li P, Liao R, Li J, Chen S, Diao W, Shi K, Zuo C, Tan S, Li J, Jiang Z, Hu Y, Wu W, Zhou J
Journal of advanced research 2026 Mar;81:781-796
Journal of advanced research 2026 Mar;81:781-796
Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids.
Ni Z, Cao C, Tian Y, Mu J, Tian H, Wang Z, Zhang S, Cao M, Yang Y, Lim WLF, Cui J, Sun H, Miao H, Wang Y, Du J, Kwok T, Chen H, Lam SM, Shui G
MedComm 2026 Mar;7(3):e70669
MedComm 2026 Mar;7(3):e70669
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Ma X, Lei P, Ren B, Xie S, Zhang Y, Wang Y, Ma W
Archives of pharmacal research 2026 Mar;49(3):357-374
Archives of pharmacal research 2026 Mar;49(3):357-374
BNIP3L-Mediated Mitophagy Inhibits Cadmium-Induced Apoptosis in the Rat Cerebral Cortex.
Wang L, Zhang Q, Hou Y, Miao W, Wen S
Journal of biochemical and molecular toxicology 2026 Mar;40(3):e70747
Journal of biochemical and molecular toxicology 2026 Mar;40(3):e70747
Rapamycin Reduces Amyloid-β Plaques and Improves Behavioral Performance in a Sex-Dependent Manner in Mouse Models of Amyloidosis.
Guo S, Fu W, Wang Y, Liu Q, Li J, Guo K, Zhang H
CNS neuroscience & therapeutics 2026 Mar;32(3):e70807
CNS neuroscience & therapeutics 2026 Mar;32(3):e70807
Trehalose Alleviates the Advancement of Temporomandibular Joint Osteoarthritis via Regulating the AMPK/ULK1 Autophagy Pathway.
Xu J, Liu Y, Zhu S, Yu W, Kang H, Bao G
Oral diseases 2026 Mar;32(3):809-821
Oral diseases 2026 Mar;32(3):809-821
ZNF16 inhibits PEDV replication through autophagy-mediated degradation of S1 protein.
Zheng D, Yang X, Qin W, Gao A, Liu Y, Sun H, Tong W, Yu H, Zheng H, Tong G, Shan T, Zhang Y, Kong N, Zheng L
Veterinary microbiology 2026 Mar;314:110912
Veterinary microbiology 2026 Mar;314:110912
Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles.
Gong Q, Zhao W, Wang T, Pan Y, Cui C, Qu Y, Zhou X
The Journal of biological chemistry 2026 Mar;302(3):111182
The Journal of biological chemistry 2026 Mar;302(3):111182
Gentiana szechenyii Kanitz Compounds Regulate Lipopolysaccharide-Induced Inflammation and Mitochondrial Autophagy Via the Toll-Like Receptor 4-Nuclear Factor Kappa B Pathway.
Zhang H, Zhang Z, Hu J, Li Y, Nan X, Yang F
Chemistry & biodiversity 2026 Mar;23(3):e03838
Chemistry & biodiversity 2026 Mar;23(3):e03838
Proximity labelling identifies proteins associated with HSV-2 pUL21 at early and late times after infection.
Holder SM, Bossert M, Finnen RL, Banfield BW
PLoS pathogens 2026 Mar;22(3):e1014027
PLoS pathogens 2026 Mar;22(3):e1014027
Astaxanthin improves assisted reproductive outcomes in patients with poor ovarian response by alleviating oxidative stress and regulating granulosa cell mitochondrial function.
Tian D, Ju H, Cheng X, Liang X, Zhu S
Journal of reproductive immunology 2026 Mar;174:104864
Journal of reproductive immunology 2026 Mar;174:104864
Cyclophilin A stabilizes the capsid protein p72 to facilitate African swine fever virus replication.
Kong H, Yang L, Zhang Z, Zhang Y, Liu L, Wang W, Song L, Zhu Y, Sun E, Li F, Bu Z, Sheng X, Zhao D
Nature communications 2026 Mar 7;17(1)
Nature communications 2026 Mar 7;17(1)
Spermine Ameliorates DSS-Induced Ulcerative Colitis in Mice by Improving Mitophagy and Intestinal Microbiota.
Yu R, Liu Y, Zheng Y, Chen S, Tong L, Wang J, Li C, Zhang C
Life (Basel, Switzerland) 2026 Mar 4;16(3)
Life (Basel, Switzerland) 2026 Mar 4;16(3)
Lactiplantibacillus pentosus JWN01 and Lactiplantibacillus plantarum JWN02 attenuate renal fibrosis and pathological autophagy in hyperuricemic nephropathy via gut-kidney axis.
Mo Q, Qin M, Liang H, Wei L, Li Y, Qin Y, Tang L, Liang J, Qian C, Liang Y, Luo S, Wei Y, Kong L, Cheng J
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118376
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118376
The segmented flavivirus ALSV-encoded nucleoprotein VP2 inhibits type I interferon production by targeting RIG-I.
Pan M, Song Z, Wang M, Zhao M, Fang S, Jin F, Tan Q, Xu W, Che L, Liu N, Sui L, Liu Q, Hou Z, Zhao Y
Microbiology spectrum 2026 Mar 3;14(3):e0248425
Microbiology spectrum 2026 Mar 3;14(3):e0248425
Resveratrol Attenuates Liver Inflammation in Non-Alcoholic Fatty Liver Disease by Activating PINK1-Mediated Mitophagy.
Tan S, Yu R, Sun L, Shen M, Pedroso JF, Chacón OC, Li C, Zhao W
Animals : an open access journal from MDPI 2026 Mar 27;16(7)
Animals : an open access journal from MDPI 2026 Mar 27;16(7)
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927
iScience 2026 Mar 20;29(3):114927
A germline-specific vesicular structure licenses mRNA activation during spermiogenesis and is hijacked in gastric cancer.
Liu M, Wang Z, Li Y, Xie Q, Xiao Z, He X, Wang G, Gao Y, Zhang Y, Zheng L, Xia X, Chen L, Dong Y, Liu S, Zhang X, Xu C, Bian S, Yuan Y, Wu H, Cao Y, Zhang J, Hua R, He X
Science bulletin 2026 Mar 2;
Science bulletin 2026 Mar 2;
Disruption of iron homeostasis by HERC2-FTL axis leads to chondrocyte loss and exacerbates osteoarthritis.
Zhong Y, Duan J, Chen Z, Ye W, Cai W, Wu R, Mao X, Dai X, Dou P
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 19;31(3)
IL-22/IL-22R signaling attenuates mitochondrial damage in PCOS by modulating granulosa cell lipid metabolism through ETS1.
Luo M, Chen Y, Chen H, Wen Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Mar 17;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Mar 17;75(1)
Astragalus Polysaccharide Alleviated Septic Associated Acute Kidney Injury Through Dual Mechanisms of RIPK1-Dependent Necroptosis and Autophagy in Macrophage.
Wang L, Zhang W, Wang Z, Zhang W, Zhang L, Li J, Mao Z, Zhang J, Liang T, Ge R, Zhang Y, Yan C, Zhang J, Liang T
Phytotherapy research : PTR 2026 Mar 17;
Phytotherapy research : PTR 2026 Mar 17;
Overexpression of As3mt Attenuates Sodium Arsenite Induced Ferritinophagy and Hepatic Lipid Accumulation in Mice.
Bao JC, Yang Y, Wang Y, Xie FS
Biological trace element research 2026 Mar 17;
Biological trace element research 2026 Mar 17;
ITPR1 mediates the PI3K/AKT/mTOR pathway to regulate cellular autophagy, affecting lipopolysaccharide-induced pediatric inflammatory bowel disease.
Zhao X, Zhang X
BMC gastroenterology 2026 Mar 16;26(1)
BMC gastroenterology 2026 Mar 16;26(1)
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
Chen SX, Qi X, Zheng XT, Bi ZM, Zhang Y, Wang YM
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
O-GlcNAcylation of YAP1 promotes lung transplant ischemia-reperfusion injury via binding to HIF1α transcription factor and activating autophagy and mitophagy.
Dai S, Wan X, Xia L, Xu L, Xie C, Wang G, Tang J
Cell death & disease 2026 Mar 15;17(1)
Cell death & disease 2026 Mar 15;17(1)
Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury.
Xu L, Wang M, Feng Y, Wang S, Qian Y, Jiang W, Xu J, Fang Y, Zhang Y, Chu L
Biomolecules 2026 Mar 13;16(3)
Biomolecules 2026 Mar 13;16(3)
Fasting-induced physiological remodeling alleviated fatty liver in laying hens through regulating hepatic lipid metabolism.
Gong Y, Zeng Q, Geng X, Zhang J, Kang X, Tian Y, Jiang R
Poultry science 2026 Mar 13;105(6):106775
Poultry science 2026 Mar 13;105(6):106775
Ubiquitin C-terminal hydrolase L3 promotes liver cancer cell proliferation by modulating the AMP-activated protein kinase signaling pathway.
Liu Y, Lu J, Wang H, Sun S, Guo B, Wang X, Wang B, Li Y, Wu T
Journal of cancer research and clinical oncology 2026 Mar 12;152(3)
Journal of cancer research and clinical oncology 2026 Mar 12;152(3)
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome.
Liu K, Hong Y, Gao Q, Huang J, Liu L, Li Y, Liang Y, Zhang S, He X, Nie X
Cellular and molecular life sciences : CMLS 2026 Mar 11;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 11;83(1)
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.
Zheng H, Tian S, Wu L, Jia G, Xiao Y, Yu X, Zuo Q, Zhou R, Min J, Wu Q, Xie H, Luo Q, Wu W
The journal of headache and pain 2026 Mar 11;27(1)
The journal of headache and pain 2026 Mar 11;27(1)
Qiang-Xin 1 formula improves cardiac function and alleviates myocardial injury in lipopolysaccharide-induced septic mice by activating calcium/calmodulin-dependent protein kinase I-mediated mitophagy.
Huang P, Wang Q, Zhu Y, Hu X, Fang X, Deng W, Cao P, He S
Journal of ethnopharmacology 2026 Mar 1;358:121033
Journal of ethnopharmacology 2026 Mar 1;358:121033
Increased Glycogenin-Exposed Residual Glycogen in Lysosomes Is the Early Pathological Finding in Asymptomatic Pompe Disease.
Shi Y, Zhang N, Sun H, Wang Y, Zhao D, Wen B, Yan C, Zhao Y, Li D
Muscle & nerve 2026 Jun;73(6):1172-1181
Muscle & nerve 2026 Jun;73(6):1172-1181
Membrane-camouflaged nanoparticle alleviates intervertebral disc degeneration via oxidative stress suppression and autophagy activation.
Niu Z, Fan Y, Chen J, Ji L, Tong Y, Yao L, Ding S, Xu H, Chen J, Zhang Q, Zhao C, Chen J, Bi Q, Xia C
Materials today. Bio 2026 Jun;38:103038
Materials today. Bio 2026 Jun;38:103038
Helicobacter pylori-secreted outer membrane vesicles induce bone loss and accelerate osteoporosis pathogenesis in mice by regulating gut microbiota and autophagy.
Zhao J, Liu J, Huang S, Ye S, Zhao S
Microbiological research 2026 Jun;307:128485
Microbiological research 2026 Jun;307:128485
Extracellular vesicle-mediated transcellular mitophagy as a modulatory target for moderate hyperoxia-induced alveolar developmental arrest in bronchopulmonary dysplasia.
Sun Y, Wang T, Yang Y, Wang R, Zhu B, Wang J, Liang G, Peng W, Zhang N, Guo X, Wang X
Free radical biology & medicine 2026 Jun;249:453-468
Free radical biology & medicine 2026 Jun;249:453-468
Urban particulate matter induces NLRP3/NLRP6 inflammasomes, autophagy, senescence and fibrotic responses by increasing CSF2 signaling in kidney cells.
Su RY, Chuang HC, Zheng CM, Ho LJ, Chen YJ, Lee YH, Chiu HW
Free radical biology & medicine 2026 Jun;249:1-13
Free radical biology & medicine 2026 Jun;249:1-13
Atractylenolide I ameliorates acute-on-chronic liver failure (ACLF) by promoting autophagy and preserving mitochondrial function through mTOR inhibition.
Tang D, Tuo F, Chen J, Ding L, Wu YN, Wang R
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168197
Biochimica et biophysica acta. Molecular basis of disease 2026 Jun;1872(5):168197
TREM2 activation suppresses central sensitisation by promoting autophagy in a chronic migraine model with recurrent nitroglycerin stimulation in mice.
Hu S, Liu X, Zhang L, Zhong S, Liang Z, Zeng W, Yi L, Zeng Z, Chen B, Wang R
British journal of pharmacology 2026 Jun;183(11):2803-2819
British journal of pharmacology 2026 Jun;183(11):2803-2819
Usenamine a potentiates anti-CRC activity of sorafenib by inducing autophagy and inhibiting YAP pathway through targeting SOD2.
Zhuge W, Kuang J, Kuang K, Rao M, Jian D, Lin H, Li Z, Li S, Zheng Y, Cho N, Li X, Cui R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158086
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158086
SIRT1 agonist SRT1720 alleviates cerebral ischemia-reperfusion injury by inhibiting lactate-mediated SOD2 Lactylation and suppressing NCOA4-mediated ferritinophagy-ferroptosis.
Qi X, Song W, Li Y, Wang W, Zhao L, Li J, Li M, Wu K, Zhao B, Gao W
Cellular signalling 2026 Jun;142:112396
Cellular signalling 2026 Jun;142:112396
Leveraging ANXA1 to enhance recombinant protein yields in CHO cells: A UPR-Mediated bioprocessing approach.
Zhao Q, Zhang HJ, Han MM, Abiti J, Dong YJ, Wang JN, Lu JT, Wang W, Zhang X, Geng SL, Qiu LL, Wang XY, Hua ZC, Wang TY, Jia YL
Synthetic and systems biotechnology 2026 Jun;12:197-208
Synthetic and systems biotechnology 2026 Jun;12:197-208
TRIM27 promotes microglial M2 polarization and neuroprotection via TBK1-dependent autophagy in cerebral ischemia-reperfusion injury.
Xie D, Hu S, Long P, Huang J, Li X, Yuan Y, Liu H, Chen Y
International immunopharmacology 2026 Jun 15;179:116597
International immunopharmacology 2026 Jun 15;179:116597
A potent icaritin derivative ameliorates Parkinson's disease via GPER-mediated mitophagy restoration and dopaminergic neuroprotection.
Wang X, Cao X, Cai M, Zhao R, Zheng Y, Zhang M, Shao C, Chen W
Bioorganic chemistry 2026 Jun 15;174:109759
Bioorganic chemistry 2026 Jun 15;174:109759
Polystyrene microplastics disrupt the blood-testis barrier via CEBPB-driven lysosomal autophagy and induce ferroptosis-like injury in human sperm, compromising embryo development.
Wu M, Li L, Zhao T, Mao Y, Lin J, Li X, Bai Y, Han F, Chen S, Peng T, Liao C, Ye X, Ke H, Huang Z, Yue M, Che Y, Song Y, Chen Z, An G
Journal of hazardous materials 2026 Jun 1;510:142073
Journal of hazardous materials 2026 Jun 1;510:142073
A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair.
Sun X, Xie S, Fang Y, Zhang D, Wang W, Sun Z, Lu J, Yue X, Kong W, Fu D, Xu X, Dai K, Wang J, Wei J, Sun X
Bioactive materials 2026 Jul;61:692-711
Bioactive materials 2026 Jul;61:692-711
GPX3 activates autophagy to protect cochlear spiral ganglion neurons from injury in age-related hearing loss.
An M, Yin H, Li Y, Cao H, Zhang Z, Yang J, Wang J, Liu T, Zhao L, Wang C, Miao R, Wang B
Free radical biology & medicine 2026 Jul;250:16-29
Free radical biology & medicine 2026 Jul;250:16-29
Autophagy in Cadmium-Induced Hepatic Injury of Rats: Protective Role of Naringenin.
Gao M, Ling H, Guo C, Hu Y, Zhu J, Wang J
Journal of applied toxicology : JAT 2026 Jan;46(1):318-328
Journal of applied toxicology : JAT 2026 Jan;46(1):318-328
Selaginella Tamariscina extract reduces UVA-induced skin photodamage via regulating apoptosis and autophagy by AKT phosphorylation.
Zhao N, Zhou X, Li Z, Liang L, Bao J, Chen X, Shu P, Zhong J
Journal of photochemistry and photobiology. B, Biology 2026 Jan;274:113343
Journal of photochemistry and photobiology. B, Biology 2026 Jan;274:113343
Astrocytes differentiated from patient iPSCs model the rare leukodystrophy MLC and uncover disease-linked maturation defects and Kir4.1 channel dysfunction.
Lanciotti A, Brignone MS, De Nuccio C, Sposito S, Caprini ES, Belfiore M, Nicita F, Veroni C, Meloni C, Carrozzo R, Rizza T, Aiello C, Sartorelli J, Bertini E, Visentin S, Ambrosini E
Neurobiology of disease 2026 Jan;218:107218
Neurobiology of disease 2026 Jan;218:107218
Sesamin exerts protective effects against diquat-induced acute kidney injury by inhibiting oxidative stress, apoptosis and autophagy: A key role for the SIRT5/FOXO3a signaling pathway.
Han S, Pu Y, Liu Z
Pesticide biochemistry and physiology 2026 Jan;216(Pt 1):106728
Pesticide biochemistry and physiology 2026 Jan;216(Pt 1):106728
Hydrogen sulfide promotes proliferation and regeneration of human cerebral microvascular endothelial cells via the sonic hedgehog signaling pathway.
Chen HY, Huang JM, Zheng P, Yang GX, Qin BB, Zang MX, Wang J, Li XB
Open life sciences 2026 Jan;21(1):20251242
Open life sciences 2026 Jan;21(1):20251242
FABP4-mediated lipid droplet accumulation drives epithelial-mesenchymal transition and aggravates alveolar epithelial barrier disruption.
Shen Z, Qi Y, Chu M, Wu M, Feng C, Li X, Liu Z, Si L, Wang Y, Zhang J, Lu X, Lu P
Clinical and translational medicine 2026 Jan;16(1):e70563
Clinical and translational medicine 2026 Jan;16(1):e70563
Ginsenoside Rc inhibits diabetic cardiomyopathy by reducing lipotoxicity through the adiponectin and autophagy pathways.
Han W, Wang Z, Guo H, Wang M, Cao L, Sun G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157615
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157615
Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux.
Cao X, Li Y, Guo B, Liu Y, Wang B, Wang H, Lu J, Wei L, Gao Y, Guo Y, Wu T
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 8;49(1):21
Cellular oncology (Dordrecht, Netherlands) 2026 Jan 8;49(1):21
Epicatechin Gallate Ameliorates UVB-Induced Photoaging by Inhibiting p38α-Mediated Autophagy and Oxidative Stress.
Yang D, Sun R, Cui Y, Li Y, Hou H, Otsuki K, Li W, Xu J, Zhang P, Zhang J
Antioxidants (Basel, Switzerland) 2026 Jan 30;15(2)
Antioxidants (Basel, Switzerland) 2026 Jan 30;15(2)
Decoding the MYC locus reveals a druggable ultraconserved RNA element.
Shi P, Yang F, Fnu T, Huang W, Aparicio AO, Kalicki CH, Trehan A, Murphy MR, Rotlevi ER, Xing L, Reilly MP, Que J, Wu X
bioRxiv : the preprint server for biology 2026 Jan 30;
bioRxiv : the preprint server for biology 2026 Jan 30;
Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Toriola MA, Timlin E, Bulbule S, Reyes A, Adedeji OM, Gottschalk CG, Barua A, Arnold LA, Roy A
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Jan 27;75(1):26
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Jan 27;75(1):26
Zalcitabine induces ferroptosis in multiple myeloma through the TFAM-cGAS-STING-SLC7A11 axis.
Hui J, Jia J, Feng J, Tang H, Xu L, Sun W, Dong H, Gao S, Zhang C, Tian B, Gao G
Journal of translational medicine 2026 Jan 27;24(1):276
Journal of translational medicine 2026 Jan 27;24(1):276
Ferroptosis-dependent small extracellular vesicles ULK1 enhances mitophagy and suppresses breast cancer migration.
Wang A, Chen M, Luo Y, Li L, Rong J, Liu L, Yi C
Hereditas 2026 Jan 26;163(1):30
Hereditas 2026 Jan 26;163(1):30
CDC25C downregulation suppresses HCC growth via mitochondrial stress-induced autophagy and apoptosis.
Miao X, Zheng F, Mo X, Wang L, Zhang Z, Li Y, Zhang Y, Chao N, Mo F
Scientific reports 2026 Jan 17;16(1):5631
Scientific reports 2026 Jan 17;16(1):5631
Thonningianin A derived from Penthorum chinense Pursh alleviates cerebral ischemia/reperfusion-mediated apoptosis and pyroptosis through the activation of PINK1/Parkin-dependent mitophagy.
Yao Q, Hu G, Yin C, Wu A, Hu G, Qin D, Zhou X, Law BY, Du X, Chen L, Li J, Lin H, Long X, Wu J, Yu L
Chinese medicine 2026 Jan 16;21(1):40
Chinese medicine 2026 Jan 16;21(1):40
Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
Xiao M, Guo W, Zeng R, Wu S, Jin X
Nature communications 2026 Jan 16;17(1):1740
Nature communications 2026 Jan 16;17(1):1740
The protective effect of asperuloside on liver injury: Insights from metabolomics and the mTOR-mediated autophagy perspective.
Huang H, Han M, Chen L, Zhao P
Journal of pharmaceutical and biomedical analysis 2026 Jan 15;268:117214
Journal of pharmaceutical and biomedical analysis 2026 Jan 15;268:117214
tRNA m(2)G methyltransferase complex THUMPD3-TRMT112 promotes pancreatic cancer progression and autophagy via modulating TFEB translation.
Yuan W, Li S, Xi Y, Tian R, Liu Y, Chen X, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Qin W, Yan C, Chen XZ, Zhou C, Tang J
Molecular cancer 2026 Jan 13;25(1)
Molecular cancer 2026 Jan 13;25(1)
Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy.
Xie X, Liu C, Liu X, Hou L, Zhang Y, Huang L, Peng W, Liu Y
Scientific reports 2026 Jan 13;16(1):5155
Scientific reports 2026 Jan 13;16(1):5155
Butyrate-Modified Hyaluronic Acid Ameliorates MPTP-Induced Parkinson's Disease via Modulating PINK1/Parkin-Involved Mitophagy and Intestinal Flora.
Sun Y, Cui L, Peng W, Chen R, Guan X, Liu J
Biomacromolecules 2026 Jan 12;27(1):134-149
Biomacromolecules 2026 Jan 12;27(1):134-149
Xi Huang Pill exerts anti-triple-negative breast cancer effects by modulating gut microbiota, regulating glycerophospholipid metabolism, and promoting autophagy homeostasis.
Gu Y, Wang Y, Qu G, Pen Y, Chen Y, Zhu X, Li Y, Wang Y, Fang F, Zhang S, Lu F
Journal of pharmaceutical and biomedical analysis 2026 Jan 1;267:117166
Journal of pharmaceutical and biomedical analysis 2026 Jan 1;267:117166
Integrated multi-omics and machine learning elucidate the pathogenic role of mitophagy in osteoarthritis and identify novel therapeutic strategies.
Dong Q, Huang H, Feng Y, Chao L, Wu Z, Zha Z, Li R, Chen J
International immunopharmacology 2026 Jan 1;168(Pt 2):115916
International immunopharmacology 2026 Jan 1;168(Pt 2):115916
Allergen-induced dendritic cell autophagy drives immune imbalance in asthma.
Li Y, Zhou M, Ren Y, Li Y, Xiang J, Deng F, Yu J, Luo Z, Liu E, Fu Z, Liu B, Ding F
International immunopharmacology 2026 Jan 1;168(Pt 2):115897
International immunopharmacology 2026 Jan 1;168(Pt 2):115897
Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy.
Zheng R, Liu Y, Zhou S, Liu G, Liu X, Yang Y, Zhang Y
Oncology reports 2026 Feb;55(2)
Oncology reports 2026 Feb;55(2)
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Su Y, Fu Q, Wu X, Che X, Jiang Z, Li X
Toxicology and applied pharmacology 2026 Feb;507:117693
Toxicology and applied pharmacology 2026 Feb;507:117693
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism.
Chen L, Lu L, Fan C, Zhu X, Pan L, Tang S, Wang Y, Peng Y, You L
Biomedical journal 2026 Feb;49(1):100870
Biomedical journal 2026 Feb;49(1):100870
Neuroprotective effects of dexmedetomidine in spinal cord injury via modulating PERK/ATF4 pathway.
Yang L, Long B, Yang H
Neurological research 2026 Feb;48(2):147-154
Neurological research 2026 Feb;48(2):147-154
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Qiu QQ, Zhang N, Xu YY, Qin JW, Yu GF, Song XR
Molecular medicine reports 2026 Feb;33(2)
Molecular medicine reports 2026 Feb;33(2)
Picornavirus VP2 protein suppresses innate immunity through selective autophagic degradation of IKBKE/IKKε.
Li K, Zhang X, Dong D, Zhu B, Wang S, Wen X, Cao W, Ru Y, Tian H, Zhu G, He J, Guo J, Dai J, Zheng H, Yang F, Zhu Z
Autophagy 2026 Feb;22(2):330-350
Autophagy 2026 Feb;22(2):330-350
L-tetrahydropalmatine attenuates methamphetamine-induced pulmonary vascular remodeling via CaSR-BMP2/mTOR signaling.
Chen L, Wang X, Zhu X, Hu WT, Yang D, Wang Y
Bioorganic chemistry 2026 Feb;169:109418
Bioorganic chemistry 2026 Feb;169:109418
Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer.
Wang S, Chen J, Cui Y, Xing J, Liu J, Jiang H, Yang H, Zhang H, Sun M, Li J, Liu W, Chen Z, Sun W, Wang X, Yang Z
Acta pharmaceutica Sinica. B 2026 Feb;16(2):1022-1045
Acta pharmaceutica Sinica. B 2026 Feb;16(2):1022-1045
Cannabidiol alleviates methamphetamine-induced autophagy and oxidative stress by suppressing sigma 1 receptor expression.
Li Y, Liu L, Miao L, Zhang Y, Li XD, Sun T, Zeng XF, Huang J, Liu JX
Cellular signalling 2026 Feb;138:112280
Cellular signalling 2026 Feb;138:112280
NSUN3-mediated m5C modification of FABP5 regulates lipid droplets through autophagy to alleviate osteoarthritis progression.
Luo Z, Liu Y, Cheng B, Li Z, Yang L, Cheng C, Fang H, Liu Y
Cellular signalling 2026 Feb;138:112238
Cellular signalling 2026 Feb;138:112238
Ginsenoside 20(S)-Rg3 alleviates cage stress induced liver injury in laying ducks.
Zong Y, Hu Z, Sun H, Tian Y, Gu T, Xu W, Chen L, Zeng T, Lu L
Poultry science 2026 Feb;105(2):106254
Poultry science 2026 Feb;105(2):106254
SREBF2 enhances lipid metabolism and represses anti-tumor immune responses in cervical cancer by increasing ACAT2.
Zhang Y, Shao Y, Li X, Zhou D, Zhou J, Yan Q, Gao W, Yang L
Communications biology 2026 Feb 7;9(1)
Communications biology 2026 Feb 7;9(1)
FRZB regulates the osteogenic differentiation of periodontal ligament stem cells in an inflammatory microenvironment through Wnt5a-mitochondrial axis.
Su Y, Wang H, Luo T, Liu J, Hu X
Cell regeneration (London, England) 2026 Feb 6;15(1):9
Cell regeneration (London, England) 2026 Feb 6;15(1):9
Lipophagy Dynamics in Hyperlipidemia Model ICR Mice Across Different High-Fat-Diet Feeding Durations.
Xue S, Guo X, Wang Q, Chen X, Yang J, Zhou Y, Zhang Y, Niu W
International journal of molecular sciences 2026 Feb 5;27(3)
International journal of molecular sciences 2026 Feb 5;27(3)
Knockout of the C4BPA Gene Promotes Mitophagy via Activation of the Pink1/Parkin Pathway and Alleviates the Inflammatory Response by Inhibiting the NF-κB Signalling Pathway in Bovine Mammary Epithelial Cells.
Zhou Y, Zhao Z, Chen X, Shao W, Lu Q, Tao Q, Xu Q, Chen R, Jiang P, Lin Z, Yu H
Veterinary sciences 2026 Feb 4;13(2)
Veterinary sciences 2026 Feb 4;13(2)
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
Fu T, Sun S, Wang Z, Zhao F, Zhen J, Ji X, Xue F, Mu Q, Wang Y, Liu Y, Wan Q
Cardiovascular diabetology 2026 Feb 3;25(1)
Cardiovascular diabetology 2026 Feb 3;25(1)
AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPK-MTOR-autophagy pathway in macrophage.
Chao R, Sun L, Xu X, Liu Z, Xu X, Ren Z, Chen X, Xu W, Chen X, Hu Y, Zhang S
Journal of nanobiotechnology 2026 Feb 3;24(1):130
Journal of nanobiotechnology 2026 Feb 3;24(1):130
Bidens biternata (Lour.) Merr. & Sherff improves liver lipid metabolism disorders in type 2 diabetic mice by activating mitophagy.
Li Y, Kang S, Wang Q, Zeng C, Dong G
Journal of ethnopharmacology 2026 Feb 28;357:120877
Journal of ethnopharmacology 2026 Feb 28;357:120877
CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy.
Tang C, Teng W, Jiang Y, Wu Y
Journal of gastrointestinal oncology 2026 Feb 28;17(1):17
Journal of gastrointestinal oncology 2026 Feb 28;17(1):17
Oncolytic adenovirus type 11-induced ferroptosis of esophageal squamous cell carcinoma cells involves in mitochondrial impairment and the mTOR pathway.
Si L, Zhao C, Chard Dunmall LS, Wang P, Cheng Z, Wang Y
BMC cancer 2026 Feb 24;26(1)
BMC cancer 2026 Feb 24;26(1)
KNSTRN knockdown impairs autophagy flux to inhibit bladder cancer progression.
Huang X, Meng Y, Song J, Zhu Y, Li J, Xi Y, Peng X, Xiong Y
iScience 2026 Feb 20;29(2):114734
iScience 2026 Feb 20;29(2):114734
MUL1 suppresses cervical cancer progression by targeting FUNDC1 for ubiquitination and inhibiting DRP1-dependent mitophagy.
Li Y, Wang F, Fang Z, Sun H
Journal of molecular histology 2026 Feb 16;57(2):79
Journal of molecular histology 2026 Feb 16;57(2):79
Therapeutic potential of magnesium diboride nanosheets in PAH-associated right heart failure: Integrated multi-omics analysis reveals ferroptosis suppression via LC3/ATG5/NCOA4/FTH1 pathway.
Jiao Q, Yang Y, Xu X, Hao J, Guo J, Wu G, Pang S, Yang W, Zhao Y, Wang L, Wang H, Dong P, Wang Y, Wang T
Free radical biology & medicine 2026 Feb 16;244:1-16
Free radical biology & medicine 2026 Feb 16;244:1-16
Lactiplantibacillus plantarum GUANKE ameliorates influenza a virus-induced inflammation and lung barrier dysfunction through enhancing mitophagy and improving oxidative phosphorylation.
Lu S, Yue K, He S, Mi J, Yang T, Yang Y, Ma H, Ren Z, Ren L, Xu J
Cellular and molecular life sciences : CMLS 2026 Feb 10;83(1):107
Cellular and molecular life sciences : CMLS 2026 Feb 10;83(1):107
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.
Lu P, Zhang F, Yang L, He Y, Kong X, Guo K, Xie Y, Xie H, Xie B, Jiang Y, Peng J
Neural regeneration research 2026 Feb 1;21(2):715-729
Neural regeneration research 2026 Feb 1;21(2):715-729
Staphylococcus aureus escapes endosomes and autophagosomes via α-hemolysin.
Xu H, Qi C, Qu C, Lou J, Wang X, Zhang H, Liu J, Liu Y
International immunopharmacology 2026 Feb 1;170:116072
International immunopharmacology 2026 Feb 1;170:116072
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
Jiashu Z, Jingbao L, Hua F, Meiqi S, Jing L, Mengyao W, Wei Z
Cellular signalling 2026 Aug;144:112517
Cellular signalling 2026 Aug;144:112517
ATP6V0A1 protects dopaminergic neurons via the autophagy-lysosomal pathway in Parkinson's disease.
Lin Y, Tan Z, Ye W, Li W, Chen H, Lin Y, Zhou M, Liu H, Liu Q, Zhang Z, Kong W, Xu Z, Lin H, Mo M, Guo W, Lin K, Tang J, Zheng Y, Zhang W, Xu P, Chen X
Neural regeneration research 2026 Aug 1;21(8):3797-3806
Neural regeneration research 2026 Aug 1;21(8):3797-3806
RP13-516M14.1 Regulates Autophagy Through miR-429 via Both a ceRNA Network and Direct Interaction.
Yang Z, Zeng A, Yu B, Xie C, Zhu W, Liu H, Gu C, Fu M
Biochemical genetics 2026 Apr;64(2):2416-2447
Biochemical genetics 2026 Apr;64(2):2416-2447
Renal-targeted tFNA-TPP nanoagonist treats acute kidney injury by amplifying mitophagy.
Xu J, Li Y, Xu J, He R, Jiang F, Lu J, Xu T, Wang J, Zhang C
Materials today. Bio 2026 Apr;37:102926
Materials today. Bio 2026 Apr;37:102926
3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair.
Wang C, Wang Y, Li X, Cao H, Wang C, Han S, Chen H, Zhao X, Yang S
Materials today. Bio 2026 Apr;37:102879
Materials today. Bio 2026 Apr;37:102879
CCT7 Regulates TRAF6-Mediated Autophagy to Promote Posttraumatic Joint Contracture.
Li Y, Zhang W, Xu W, Huang Y, Cai H, Zhang N, Liang T, Liu G
Journal of cellular and molecular medicine 2026 Apr;30(7):e71051
Journal of cellular and molecular medicine 2026 Apr;30(7):e71051
MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.
Shang H, Yang S, Sun M, Zhao Y, Guo R, Wang W, Qian B, Li Y, Hu M, Bian X, Cao Q, Li C, Fan B, Li B
PLoS pathogens 2026 Apr;22(4):e1014170
PLoS pathogens 2026 Apr;22(4):e1014170
Hydrogen-Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy.
Xu Z, Cui X, Chu H, Wan H, Xie Y, Wang Y, Ni Q, Ding X, Song G
Journal of diabetes 2026 Apr;18(4):e70209
Journal of diabetes 2026 Apr;18(4):e70209
Epigenetic H3K4me3 activation of miR-155-5p promotes intervertebral disc degeneration via autophagy and ageing in nucleus pulposus cells.
Wang X, Sun H, Xiao W, Zhang Y, Lu X, Gong Z, Li D, Liu S, Xia X, Wang H, Shao M, Xu G, Ma X
Non-coding RNA research 2026 Apr;17:112-127
Non-coding RNA research 2026 Apr;17:112-127
Extracorporeal Shock Wave Therapy Promotes Peripheral Nerve Regeneration Through ERK1/2-Mediated Autophagy.
Xiang X, Wu X, Ling S, Zhu J, Zhang J, Fu T
Annals of the New York Academy of Sciences 2026 Apr;1558(1):e70275
Annals of the New York Academy of Sciences 2026 Apr;1558(1):e70275
Celastrol triggers CAV-1-mediated mitochondrion cholesterol metabolism and mitophagy to suppress liver cancer.
Li HF, Zhang CJ, Shi YN, Zhu N, Yang Q, Long JP, Liang YT, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157989
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157989
Diosmetin alleviates hyperuricemic nephropathy by activating the BNIP3/Nrf2/GPX4 pathway to inhibit ferroptosis of renal tubular epithelial cells induced by monosodium urate crystals.
Hu C, Dong C, Yang H, Yu Z, Li Y, Qiu Y, Mei Z, Xu L
The Journal of nutritional biochemistry 2026 Apr;150:110241
The Journal of nutritional biochemistry 2026 Apr;150:110241
Targeting the GPX4-FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis-Associated Lung Injury.
Li Z, Liu C, Ma Z, Zheng D, Wang R, Yu Y, Chen G, Li C, Bu Y, Cao H, Zhang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e16488
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e16488
IRF4 Enhances Radiosensitivity of Cervical Cancer by Inhibiting the PI3K/Akt/mTOR Pathway to Regulate Autophagy.
Gao M, Cui Z, Song H, Li Y, Li A, Zheng J, Liu L, Lin X, Fu W, Sun Y
Cancer science 2026 Apr;117(4):958-971
Cancer science 2026 Apr;117(4):958-971
The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency.
Yang M, Mo Z, Walsh K, Liu W, Irahal IN, Arnoult D, Guo X
Nature communications 2026 Apr 9;
Nature communications 2026 Apr 9;
Targeting Fgr-STAT3 Mediated Autophagy Inhibition in the Spinal Cord Alleviates Neuropathic Pain in Rats.
He L, Zhang Y, Yang C, Huang Z, Zou K, Deng Q, Zhang J, Mulati M, Sun B, Guo Q, Huang C
Neuroscience bulletin 2026 Apr 9;
Neuroscience bulletin 2026 Apr 9;
African swine fever virus hijacks lipolysis induced by chaperone-mediated autophagy to upregulate fatty acid β-oxidation and promote viral replication.
Yang X, Xiong X, Liu H, Wen X, Shi X, Ma H, Wang R, Cao W, Yang F, Ru Y, Tian H, He J, Guo J, Han S, Zhu Z, Zheng H
mBio 2026 Apr 8;17(4):e0336825
mBio 2026 Apr 8;17(4):e0336825
Evolutionarily conserved signaling intermediate in Toll pathways facilitates exercise-induced amelioration of skeletal muscle atrophy by maintaining mitochondrial quality control in middle-aged mice.
Fan J, Wen X, Duan X, Zhang X, Zhang T
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Apr 7;81(5)
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Apr 7;81(5)
A tumor-derived mitochondrial tsRNA drives vascular invasion of lung adenocarcinoma by promoting ribosomal assembly in endothelial cells.
Liang S, Wang Q, Zhang M, Song X, Zhang Y, Wang H, Feng Y, Li R, Xia W, Xu L, Dong G, Mao Q, Jiang F
Cancer letters 2026 Apr 28;644:218324
Cancer letters 2026 Apr 28;644:218324
Stabilizing MARCH7 as a ferro-guardian against ferroptosis.
Huang W, Wang R, Yang X, Yang S, Yang X, He G, Dai S, Li C, Gao L, Zhang T, Zhang P, Chen R, Zheng K, Wu J, Min J, Ba Q, Wang F, Zhang Q
Cell 2026 Apr 27;
Cell 2026 Apr 27;
Overexpression of miR-7641 activates ox-LDL-induced autophagy in macrophages by regulating USP7.
Tian P, Du Q, Zeng F, Chen J, Wang P, Zhang L, Li Y
Molecular biology reports 2026 Apr 22;53(1)
Molecular biology reports 2026 Apr 22;53(1)
Pestiviruses utilize pyrimidine metabolism to regulate mitophagy for viral replication.
Zhao B, Chen J, Cheng Y, Li Y, Zhong L, Chen J, Bi X, Bai J, Dai Q, Ye Y, Zou L, Wang L, Zhou B
Autophagy 2026 Apr 20;:1-22
Autophagy 2026 Apr 20;:1-22
UHRF1-mediated DNA 5-mC modification drives super-enhancer redistribution and impedes osteogenesis via TGM2-regulated autophagic flux in senile osteoporosis.
Pang P, Chen J, Li Q, Su Z, Lin J, Zeng Y, Zhang W, Xiao Z, Chen Z, Liu Z, Lin Y, Zheng G, Yu W, Xie Z
Journal of advanced research 2026 Apr 17;
Journal of advanced research 2026 Apr 17;
Dual-Shell Chitosan/Ferritin Nanocages Enhance the Stability, Intestinal Transport, and Antiviral Activity of EGCG against HBV.
Dong Y, Yin X, Shan X, Hu Y, Zhu C
Journal of agricultural and food chemistry 2026 Apr 15;74(14):11579-11591
Journal of agricultural and food chemistry 2026 Apr 15;74(14):11579-11591
Xuming tongmai decoction modulates astrocyte polarization and mitophagy via the PINK1/Parkin pathway in a rat model of acute ischemic stroke.
Ran L, Lan X, Zeng Z, Yu X, Yang R, Tang J
Brain research 2026 Apr 15;1877-1878:150203
Brain research 2026 Apr 15;1877-1878:150203
Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway.
Liu X, Liu S, Xu G, Chen W, Shi Y, Wang G, Cao Y, Lu G, Ning Y, Zhao Y
Biochemical pharmacology 2026 Apr 12;250(Pt 1):117962
Biochemical pharmacology 2026 Apr 12;250(Pt 1):117962
Sustained high-fat diet intake differentially regulates hepatic lipophagy and metabolic adaptation after bariatric surgery in obese rats.
Huang SY, Liao CY, Chang CW, Wu CY, Chiang PY, Chang CC, Kao WY
The Journal of nutritional biochemistry 2026 Apr 12;155:110375
The Journal of nutritional biochemistry 2026 Apr 12;155:110375
Saikosaponin D Alleviates Liver Ischemia-Reperfusion Injury by Inhibiting Mitophagy-Associated Ferroptosis via the STAT3/PINK1 Pathway.
Liu X, Xu Y, Yu X, Feng X, Han Y, Cai H, Du J, Chen L
Phytotherapy research : PTR 2026 Apr 12;
Phytotherapy research : PTR 2026 Apr 12;
African swine fever virus pE199L, as a mitophagy receptor, suppresses antiviral innate immunity to promote viral replication.
Li X, Ren B, Zhang D, Dan M, Liu D, Zhang Z, Zhao J, Nan Y, Hiscox JA, Stewart JP, Zhu Z, Zhao Q, Sun Y
Autophagy 2026 Apr 11;:1-20
Autophagy 2026 Apr 11;:1-20
Suppression of Nr1d1/Bnip3-dependent mitophagy by notch signaling aggravates inflammatory response in RSV-infected mice lungs.
Lei Y, Liu Z, Du H, Zhang R, Hu H, Yang P, Zheng J, Zhao D
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 10;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 10;75(1)
USP2 Attenuates Spermatogenic Cell Apoptosis Via PINK1/Parkin-Dependent Mitophagy in Varicocoele: A Functional Study.
Yao RJ, Xiao H, Zheng JH, Lin B, Liao SJ, He HH, Xu N, Zhou HL
Andrology 2026 Apr 10;
Andrology 2026 Apr 10;
Upstream Stimulatory Factor 2 Protects Cardiomyocytes by Regulating Mitochondrial Homeostasis.
Wu W, Zhao K, Li K, Zhu Z, Li Y, Chen J, Ding H, Zhang X
International heart journal 2025;66(2):302-312
International heart journal 2025;66(2):302-312
Perfluorooctane sulfonate induces hepatotoxicity through promoting inflammation, cell death and autophagy in a rat model.
Tang L, Zhu J, Zhuge S, Yu J, Jiang G
The Journal of toxicological sciences 2025;50(2):45-55
The Journal of toxicological sciences 2025;50(2):45-55
Mitochondrial autophagy inhibits nucleotide-binding oligomerization domain-like receptor protein 3-mediated pyroptosis and alleviates endothelial cell injury in pregnancy-induced hypertension.
Zhang M, Zhang X, Mao L
CytoJournal 2025;22:60
CytoJournal 2025;22:60
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
Zheng Z, Chen J, Xue X, Ma X, Zhang S, Wang M, Xue Y, Jia Y
International journal of biological sciences 2025;21(9):4215-4230
International journal of biological sciences 2025;21(9):4215-4230
DARS2 Promotes Bladder Cancer Progression by Enhancing PINK1-Mediated Mitophagy.
Li D, Su H, Deng X, Huang Y, Wang Z, Zhang J, Chen C, Zheng Z, Wang Q, Zhao S, Chen ZS, Chen H, Hou L, Tan W, Li F
International journal of biological sciences 2025;21(4):1530-1544
International journal of biological sciences 2025;21(4):1530-1544
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Zhou X, Zhao Y, Huang S, Shu H, Zhang Y, Yang H, Ren Y, Zhou X, Liu W, Song T, Zhao J, Ma J
International journal of biological sciences 2025;21(3):1259-1274
International journal of biological sciences 2025;21(3):1259-1274
Astragaloside IV Alleviates H(2)O(2)-Induced Mitochondrial Dysfunction and Inhibits Mitophagy Via PI3K/AKT/mTOR Pathway.
Qi M, Wang Q, Sun R, Cheng Z, Li M, Fan X, Bai F, Yu J
Cardiovascular therapeutics 2025;2025:9549175
Cardiovascular therapeutics 2025;2025:9549175
Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice.
Zou X, Chen W, Shao Y, Shi T, Ke Y
Canadian journal of gastroenterology & hepatology 2025;2025:9507266
Canadian journal of gastroenterology & hepatology 2025;2025:9507266
lncRNA NKILA Promotes Warburg Effect and Immune Escape in Intrahepatic Cholangiocarcinoma by Regulating the MTX1/TOMM40 Axis.
Zhu M, Zhu H, Zhou Z, Zheng H, Dong Z, Dong W, Wan X
Mediators of inflammation 2025;2025:7712817
Mediators of inflammation 2025;2025:7712817
The Active Ingredients and Potential Mechanism of Qijia Rougan Decoction in Autophagy and Hepatic Stellate Cell Activation Modulation in Liver Fibrogenesis.
Li GY, Li BX, Song HF, Gou JW, Wen L, Feng QS
Journal of analytical methods in chemistry 2025;2025:4646858
Journal of analytical methods in chemistry 2025;2025:4646858
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Wang J, Qi X, Zhao W, Hao Z, Wang K, Li Y, Wang Y, Zhang Y
PloS one 2025;20(8):e0329847
PloS one 2025;20(8):e0329847
Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling.
Li M, Hu X, Hu X, Gao F, Cui Y, Wei X, Qin Y, An X, Zhao Y, Gao Y
PloS one 2025;20(4):e0320509
PloS one 2025;20(4):e0320509
Identification and validation of key autophagy-related genes in lupus nephritis by bioinformatics and machine learning.
Zhang S, Hu W, Tang Y, Chen X
PloS one 2025;20(1):e0318280
PloS one 2025;20(1):e0318280
Inhibition of ATG7 promotes orthodontic tooth movement by regulating the RANKL/OPG ratio under compression force.
Yang Z, Chen M, Liao X, Ma L, Liang C, Li Y, Hu J
Open medicine (Warsaw, Poland) 2025;20(1):20251252
Open medicine (Warsaw, Poland) 2025;20(1):20251252
Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy.
Mao Y, Du X, Wang W, Dong T, Zhu M, Niu J, Li M, Jiang J, Han L, Yang X
International journal of nanomedicine 2025;20:11081-11097
International journal of nanomedicine 2025;20:11081-11097
RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells.
Zhang Y, Liu H, Wang K, Zheng J, Luan H, Xin M
Drug design, development and therapy 2025;19:67-82
Drug design, development and therapy 2025;19:67-82
Artesunate Mitigates Sepsis-Induced Acute Kidney Injury via Lactate/AMPK/mTOR-Regulated Autophagy Based on Multi-Omics.
Chen H, Du P, Guo R, Li X, Zhang L, Duan J, Chen M, Guo J, Li Y, Jiang T
Drug design, development and therapy 2025;19:5911-5928
Drug design, development and therapy 2025;19:5911-5928
Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy.
Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS
Drug design, development and therapy 2025;19:369-387
Drug design, development and therapy 2025;19:369-387
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Ding F, Zhang W, Liu T, Rong X, Cui Y, Meng L, Wang L, Liu B, Li M
Drug design, development and therapy 2025;19:2173-2188
Drug design, development and therapy 2025;19:2173-2188
Enhancing autophagy mitigates LPS-induced neuroinflammation by inhibiting microglial M1 polarization and neuronophagocytosis.
Guo J, Li Y, Ma K, Su G
Frontiers in cellular neuroscience 2025;19:1546848
Frontiers in cellular neuroscience 2025;19:1546848
Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy.
Ma J, Ding L, Zang X, Yang Y, Zhang W, Li X, Zhao D, Zhang Z, Wang Z, Zhao L, Tong X
Journal of inflammation research 2025;18:8447-8475
Journal of inflammation research 2025;18:8447-8475
Rapamycin and Chloroquine Modulate Insulin Resistance and Hepatic Steatosis in a High-Fat/High-Cholesterol Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Mouse Model.
Liu Q, Du Q, Yuan X, Zhang T, Li J, Xu J, Xie R
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:4059-4072
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:4059-4072
Sigma-1 Receptor Rescues Autophagy Through AMPK/mTOR Signaling Pathway in Sepsis-Induced Acute Kidney Injury.
Jiang W, Zhang J, Zhang Y, Huang Z
International journal of general medicine 2025;18:1917-1931
International journal of general medicine 2025;18:1917-1931
CAPN1 Promotes Pseudomonas aeruginosa-Induced Infection by Interacting with TFEB and Inhibiting Autophagy.
Wu Y, Chen M, Chen H, Pan L, Zhao J, Sun S, Zhang N, Xu J
Journal of innate immunity 2025;17(1):176-197
Journal of innate immunity 2025;17(1):176-197
Nurr1 deficiency impairs autophagy-lysosomal function through GBA-dependent transcriptional regulation in Parkinson's disease pathogenesis.
Cheng C, Yang H, Tian L, Ni Y, Jia C, Le W, Wang Q
Frontiers in aging neuroscience 2025;17:1612389
Frontiers in aging neuroscience 2025;17:1612389
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality.
Zhou X, Wang N, Wei J, Li G, Lue Z, Liu C, Bao Q, Feng Z, Zhang M, Huang H, Li Y, Wang J, Zhang X
Frontiers in pharmacology 2025;16:1732154
Frontiers in pharmacology 2025;16:1732154
Comprehensive analysis of IGFL1 in colorectal cancer and its promotion of tumour progression via inhibition of lipophagy.
Wang A, Zhou Y, Deng Z, Duan Y, Dai Z, Jiang D
Frontiers in immunology 2025;16:1719525
Frontiers in immunology 2025;16:1719525
Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation.
Yu J, Kang X, Chang R, Zhang C, Yang S, Chen L, Wang X, Hu B, Wang Z, Gong L, Liu L
Frontiers in pharmacology 2025;16:1704023
Frontiers in pharmacology 2025;16:1704023
Targeting mitophagy in diabetic retinopathy: novel insights into SQSTM1/BNIP3L pathway regulated by luteolin.
Zhang S, Wu J, Zhang Y
Frontiers in pharmacology 2025;16:1593213
Frontiers in pharmacology 2025;16:1593213
Bletilla striata polysaccharide induces autophagy through PI3K/AKT signaling pathway to promote the survival of cross-boundary flap in rats.
Yue Q, Zeng X, Yang M, Chen J, Liu L, Liu H
Frontiers in pharmacology 2025;16:1544932
Frontiers in pharmacology 2025;16:1544932
Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway.
Zhang P, Jin M, Zhang L, Cui Y, Dong X, Yang J, Zhang J, Wu H
Frontiers in pharmacology 2025;16:1540835
Frontiers in pharmacology 2025;16:1540835
Moderate intensity continuous training mitigates hypertension-induced renal fibrosis by inhibiting HIF-1α-mediated autophagy.
Li Y, Yang X, Chen Z, Dong W, Chen X, Wang W, Li L, Ma W, Chang Q
Frontiers in physiology 2025;16:1529811
Frontiers in physiology 2025;16:1529811
Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiments.
Yin B, Ren J, Liu X, Zhang Y, Zuo J, Wen R, Pei H, Lu M, Zhu S, Zhang Z, Wang Z, Zhai Y, Ma Y
Frontiers in pharmacology 2025;16:1524448
Frontiers in pharmacology 2025;16:1524448
αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke.
Yan Y, Wu L, Wang L, Wang D, Huang M, Peng J, Huang Y
Frontiers in pharmacology 2025;16:1504683
Frontiers in pharmacology 2025;16:1504683
Splicing factor 3b subunit 4 (SF3b4) is mediated by EP300 and CREBBP to promote colorectal cancer (CRC) proliferation by enhancing autophagy.
Wu T, Xiao Z, Su B, Yan Z, Zhao Y, Huang C, Zhou L, Tian H, Zhang G
American journal of cancer research 2025;15(6):2826-2842
American journal of cancer research 2025;15(6):2826-2842
Ultrasound-activated erythrocyte membrane-camouflaged Pt (II) layered double hydroxide enhances PD-1 inhibitor efficacy in triple-negative breast cancer through cGAS-STING pathway-mediated immunogenic cell death.
Wu Y, Zhao Z, Ma M, Zhang W, Liu W, Liang X, Zhao T, Luo Y, Wang Y, Li M, Li T, Liu C, Luo X, Wang S, Li W, Zeng W, Wang H, Li W, Wu T, Ke Z, Luo F
Theranostics 2025;15(4):1456-1477
Theranostics 2025;15(4):1456-1477
The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinoma.
Liu R, Li X, Xu J, Yan L, Hu K, Shi M, Zhang Y, Zhao Y, Fan Y, Wang G, Guo Y, Feng Y, Liu P
Theranostics 2025;15(17):9091-9113
Theranostics 2025;15(17):9091-9113
Neutrophil hitchhiking liposomal drugs for starvation therapy in endometriosis.
Zhou M, Wang Y, Li C, Li J, Dou R, Jiang H, Zhang Y, Chen D, Zhang J, Zhu S
Theranostics 2025;15(10):4848-4860
Theranostics 2025;15(10):4848-4860
GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.
Cheng Y, Zheng G, Huang H, Ni J, Zhao Y, Sun Y, Chang Y, Liu S, He F, Li D, Guo Y, Miao Y, Xu M, Wang D, Zhang Y, Hua Y, Yang S, Fan G, Ma C
Theranostics 2025;15(10):4345-4367
Theranostics 2025;15(10):4345-4367
Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.
Xu M, Wang T, Deng X, Liu Y, Zhu Z, Barkema HW, Cobo ER, Kastelic JP, Zhou X, Han B
Frontiers in cellular and infection microbiology 2025;15:1731492
Frontiers in cellular and infection microbiology 2025;15:1731492
Overexpression of BNIP3 in renal carcinoma cells can promote apoptosis of renal carcinoma cells through HIF-1α-BNIP3-mediated autophagy.
Huang L, Wang L, Yuan D, Xu Y, Wang Y, Yao K, Zhong X, Liu Q, Jia K, Lei L, Wang H, Liu D
Frontiers in oncology 2025;15:1614378
Frontiers in oncology 2025;15:1614378
Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer.
Ren M, Ma F, Qin M, Sun X, Wang Y, Zhu X, Xu Y, Cao N, Zhao R, Zhang Y, Zhu J, Pan Y, Zhao A
Frontiers in oncology 2025;15:1563006
Frontiers in oncology 2025;15:1563006
Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.
Lu B, He J, Pan S, Wei J, Li B, Cao N, Huang Y, Tian Y, Cheong N, Chen Y, Xu D, Li W
Frontiers in veterinary science 2025;12:1672417
Frontiers in veterinary science 2025;12:1672417
Sestrin2 Regulates Mitochondrial Function and Autophagy via Nrf2/SIRT3 Signaling to Ameliorate Hypoxia/Reoxygenation-Induced Rat's Cardiomyocyte Injury.
Liu T, Kong J, Li Z, Xi S, Liu L
Drug development research 2025 Sep;86(6):e70150
Drug development research 2025 Sep;86(6):e70150
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Wan J, Cai X, Liao Z, Liu Y, Liu Q, Zhang C, Long F
IUBMB life 2025 Sep;77(9):e70048
IUBMB life 2025 Sep;77(9):e70048
ADSC-EVs Activate Autophagy Via the AKT/FOXO1 Pathway to Inhibit Tendon Fibrosis.
Zhang AD, Liu HC, Zhang TT, Li XQ, Wu Y, Guo YJ, Li RW, Xu B, Jiang ZT, Li ZZ
The American journal of sports medicine 2025 Sep;53(11):2618-2632
The American journal of sports medicine 2025 Sep;53(11):2618-2632
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation.
Pu Q, Gao F, Xiao Y, Wu J, Wang C, Mo X, Zhang Z, Zheng R, Wu D
Toxicology 2025 Sep;516:154193
Toxicology 2025 Sep;516:154193
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Shafik MS, El-Tanbouly DM, Bishr A, Soubh AA, Attia AS, Muhammad RN
Toxicology and applied pharmacology 2025 Sep;502:117423
Toxicology and applied pharmacology 2025 Sep;502:117423
TTK promotes mitophagy by regulating ULK1 phosphorylation and pre-mRNA splicing to inhibit mitochondrial apoptosis in bladder cancer.
Chen K, Chen J, Cong Y, He Q, Liu C, Chen J, Li H, Ju Y, Chen L, Song Y, Xing Y
Cell death and differentiation 2025 Sep;32(9):1691-1706
Cell death and differentiation 2025 Sep;32(9):1691-1706
Phillygenin ameliorates myocardial ischemia-reperfusion injury by inhibiting cuproptosis via the autophagy-lysosome degradation of CTR1.
Chen G, Wei M, Zhao CY, Zhang AY, Su JB, Ni ZR, Cai WW, Hou B, Du B, Liu MH, Xu GW, Yang L, Xu AJ, Wen YY, Wang J, Zou H, Zhuang YY, Xing HY, He T, Li YF, Lu QB, Zhu J, Zhu XX, Li KL, Sun HJ
Free radical biology & medicine 2025 Sep;237:542-557
Free radical biology & medicine 2025 Sep;237:542-557
Resveratrol ameliorates streptozotocin induced renal inflammation and promotes autophagy by mediating the SphK1 pathway via Sirt1 in Wistar rats.
Feng F, Li S, Shi J, Chen W, Deng Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115588
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115588
Huotan Jiedu Tongluo Decoction targets Nrf2-mediated macrophage autophagy to inhibit ferroptosis and reduce atherosclerotic lesions.
Gao D, Tian T, Yu K, Shao X, Shi R, Xue W, Feng H, Zhao Z, Deng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157012
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157012
The antitumor effects of lupenone on colon cancer and its mechanistic insights.
Li R, Wang R, Wang X, Lin L, Wang C, Jian Q, Xu Q, Cheng Y, Lin J, Zhang B, He L, Yue R, Zheng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156939
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156939
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
Kong X, Hu R, Zhang P, Li Q, Song K, Gu H, Zheng J, Liu S, Liu L, Jin L, Cheng L, Li C, Wei Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e07178
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e07178
Investigating the role of 1,8-Cineole in mitigating ferroptosis in a HFSD/STZ diabetes mellitus type 2-induced model: A GEO data analysis approach.
Yang H, Chen Y, Wu G, Ren P, Chen T, Liu J, Zhang B, Ma X, Jiang F, Li Y, Tao L, Shen X
European journal of pharmacology 2025 Sep 5;1002:177846
European journal of pharmacology 2025 Sep 5;1002:177846
ARIH1 Promotes Preeclampsia by Inducing MFN2-Dependent Hypoxia-Triggered Mitophagy and Endoplasmic Reticulum Stress in Trophoblasts.
Liu H, Deng Y, Peng M, Nie Y, Chen J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71060
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71060
TFAP2A induces cisplatin resistance via BNIP3-mediated mitophagy in non-small cell lung cancer.
Guo LL, Yang XH, Jin HZ, Tian L
Translational cancer research 2025 Sep 30;14(9):5353-5369
Translational cancer research 2025 Sep 30;14(9):5353-5369
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of SAT1 and GPX4 expression.
Li H, Cao F, Liu D, Tao L
Communications biology 2025 Sep 26;8(1):1367
Communications biology 2025 Sep 26;8(1):1367
PINK1 functions in mitophagy and mitochondrial homeostasis during mice oocyte maturation.
Wang S, Wu X, Zhang M, Zhu Y, Guo Y, Song S, Zeng S
Cell & bioscience 2025 Sep 26;15(1):126
Cell & bioscience 2025 Sep 26;15(1):126
Comparison of the therapeutic efficacy of leukocyte-poor and leukocyte-rich platelet-rich plasma in rabbit knee osteoarthritis and the study of autophagy mechanism.
Sun L, Wang Y, Zhang K, Chen X, Shi H
BMC musculoskeletal disorders 2025 Sep 24;26(1):857
BMC musculoskeletal disorders 2025 Sep 24;26(1):857
The reduced DLG5 promotes doxorubicin resistance in breast cancer cells MCF-7 through regulating autophagy.
Che J, Wang X, Chen B, Wang H, Feng Q, Sun J, Xu C, Song Z
Discover oncology 2025 Sep 24;16(1):1700
Discover oncology 2025 Sep 24;16(1):1700
Coordination of autophagosome closure and release by the Alzheimer's disease-associated protein BIN1.
Palmer JE, Puri C, O'Rourke RS, Son SM, Sang C, Huang YA, Rubinsztein DC
Cell reports 2025 Sep 23;44(9):116266
Cell reports 2025 Sep 23;44(9):116266
The BPIFA2 - LRP5 axis orchestrates mitochondrial dysfunction to mediate kidney injury in lupus nephritis.
Liu Y, Tian Y, Wang H, Li N, Zhuo R, Cui H, Miao X, Liu J, Liu Q, Zhang W, Guo H, Xing L, Yang L, Feng X, Liu S
International immunopharmacology 2025 Sep 23;162:115114
International immunopharmacology 2025 Sep 23;162:115114
Melatonin attenuates ischemia-reperfusion-induced acute kidney injury by regulating abnormal autophagy and pyroptosis through SIRT1-mediated p53 deacetylation.
Sun C, Liu J, Li H, Yan Y
International immunopharmacology 2025 Sep 23;162:115092
International immunopharmacology 2025 Sep 23;162:115092
Adipose-derived stem cell exosomes promote neurological recovery after subarachnoid hemorrhage via AMPK/mTOR-mediated TFEB activation.
Liu M, Li S, Wu L, Liu M, Zeng C, Shen J, Cai Z, Yin J, Wu G
Neurological research 2025 Sep 22;:1-12
Neurological research 2025 Sep 22;:1-12
LINC01018 attenuates hepatic lipid accumulation by inducing autophagy via DHX9 pathway in alcohol-associated liver disease.
Ni B, Yang F, Zhao L, Li L, Liang X, Xu R, Xu Y, He Y, Yuan C, Chen W, Zhang Q
International journal of biological macromolecules 2025 Sep 2;328(Pt 1):147298
International journal of biological macromolecules 2025 Sep 2;328(Pt 1):147298
CPNE5 overexpression inhibits cardiomyocytes apoptosis by promoting the degradation of FAS receptor.
Zhao T, Bai Y, Fei Y, Wei Z, Yao P, Che Q, Zhang Y, Yan J, Chen K, Wu Z, Qiu J, Wang Y, Li W, Wang Q, Li Y
iScience 2025 Sep 19;28(9):113302
iScience 2025 Sep 19;28(9):113302
Salidroside Attenuates Cerebral Ischemia-Reperfusion Injury via ERβ/BNIP3-Mediated Mitochondrial Autophagy Activation in a Rat Model.
Rong X, Lu P, Li Y, Wang H, Yue Y, Wang H, Ji Z, Jiang L
Neurochemical research 2025 Sep 11;50(5):297
Neurochemical research 2025 Sep 11;50(5):297
11β-HSD1 inhibitor alleviates sepsis-induced cardiac dysfunction by regulating macrophage polarization via the AMPK/mTOR autophagy pathway.
Zhang Z, Yin B, Zhu D, Wu D, Huang M, Zhou S
Journal of cardiology 2025 Sep 10;
Journal of cardiology 2025 Sep 10;
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
Li M, Zhu L, Xu Y, Han Z
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132
CUMS stress facilitates hippocampal neural mitophagy through FIS1/MFF-mediated mitochondrial fragmentation.
Qiu X, Lai S, Zhang Y, Huang S, Zhang J, Tan Y, Li H, Liu J, Huang Y, Zhang Z
Journal of neurophysiology 2025 Sep 1;134(3):952-961
Journal of neurophysiology 2025 Sep 1;134(3):952-961
Arylsulfatase K attenuates airway epithelial cell senescence in COPD by regulating parkin-mediated mitophagy.
Yang R, Zhan Y, Deng Z, Zhang J, Chen S, Zhang Y, Fu H, Meng X, Wu J, Gu Y, Huang Q, Wang C, Xie J
Redox biology 2025 Oct;86:103793
Redox biology 2025 Oct;86:103793
Bim and Mcl-1 coordinate NVP-BEZ235-induced renal cell carcinoma cell apoptosis.
Ou YC, Li JR, Yu TM, Wu CC, Liao SL, Chen WY, Kuan YH, Chen CJ
Archives of biochemistry and biophysics 2025 Oct;772:110549
Archives of biochemistry and biophysics 2025 Oct;772:110549
Nitrate-driven maintenance of lipid homeostasis by M2 macrophages alleviates atherosclerosis via downregulation of LOX1 expression and reduction of lipid deposition.
Si Y, Du H, Li S, Zhang C, Wang J, Wang S, Zhou J
Science China. Life sciences 2025 Oct;68(10):2995-3009
Science China. Life sciences 2025 Oct;68(10):2995-3009
Effect of activated autophagy on an animal model of vestibular migraine-like attacks.
Li H, Huang Y, Chen Q, Zhai Q, Zhang C, Yu Q, Chen S, Ying C, Pan Y
Experimental neurology 2025 Oct;392:115366
Experimental neurology 2025 Oct;392:115366
SAMHD1 deficiency disrupts macrophage autophagy-lysosomal homeostasis and promotes inflammation via the mTOR-MITF-CTSD axis in ulcerative colitis.
Yaxian L, Xiaodong W, Futao M, Huizhen W, Chuansheng W, Mengdi M, Bo Y, Yida L, Xin X, Ziqing F, Mingdian L, Yuxian S, Yongxiang L
International journal of biological macromolecules 2025 Oct;327(Pt 1):147188
International journal of biological macromolecules 2025 Oct;327(Pt 1):147188
Oxymatrine attenuates pulmonary fibrosis via APE1‑mediated regulation of the PINK1/Parkin pathway.
Xu W, Xie T, Zhang B, Zhao J, Zhang L, Zheng Y, Ding Y
Molecular medicine reports 2025 Oct;32(4)
Molecular medicine reports 2025 Oct;32(4)
Enhancement of photodynamic reaction by chloroquine through apoptosis induction, lipid peroxidation augmentation, and autophagy inhibition using IR-783.
Lange N, Szlasa W, Kunachowicz D, Kalinin J, Kulbacka J
Journal of photochemistry and photobiology. B, Biology 2025 Oct;271:113242
Journal of photochemistry and photobiology. B, Biology 2025 Oct;271:113242
Synthesis and anticancer studies of Ru/Ir arene complexes bearing oleanolic acid in acute promyelocytic leukemia cells.
Dai XY, Shen ZQ, Zhang Y, Liu H, Ren M, Wang P, Li J, Xue X, Liu HK
Journal of inorganic biochemistry 2025 Oct;271:112959
Journal of inorganic biochemistry 2025 Oct;271:112959
Maresin1 ameliorates osseointegration in type 2 diabetes mellitus by promoting FAM134B-mediated ER-phagy in osteoblasts.
Gui H, Wang X, Wu A, Li B, Zhang B, Diao J, Chen J, Zhang X, Wu D, He Q, Xu X, Zhang D
Biochemical pharmacology 2025 Oct;240:117099
Biochemical pharmacology 2025 Oct;240:117099
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Wang X, Liu T, Fei Y, Zhang S, Yang Y, Chen Z, Zhu R, Deng S, Zhang T, Wu D, Xu Y
Free radical biology & medicine 2025 Oct;238:595-610
Free radical biology & medicine 2025 Oct;238:595-610
Sestrin2 improves intestinal ischemia-reperfusion injury through the TFEB-mediated autophagy/lysosomal pathway.
Xie JY, Ye M, Luo J, Hu N, Zhang YG, Zhang LL, Weng ZY, Fu XY, Chen R, Meng QT
Free radical biology & medicine 2025 Oct;238:344-359
Free radical biology & medicine 2025 Oct;238:344-359
HMGA2 Attenuates Tendon Stem/Progenitor Cell Senescence Via PI3K/AKT-Mediated Mitophagy Activation and SASP Suppression.
Wang H, Dai GC, Gao YC, Liu XY, Lu PP, Cao MM, Sheng RW, Shi L, Cheng Z, Li YJ, Rui YF
Stem cell reviews and reports 2025 Oct;21(7):2188-2199
Stem cell reviews and reports 2025 Oct;21(7):2188-2199
A prognostic model of platinum resistance in osteosarcoma: Key roles of BNIP3, MYC, and ACTA2.
Che W, Luo X, Xu X, Qi J
Computers in biology and medicine 2025 Oct;197(Pt A):111001
Computers in biology and medicine 2025 Oct;197(Pt A):111001
Berberine partially ameliorates cardiolipotoxicity in diabetic cardiomyopathy by modulating SIRT3-mediated lipophagy to remodel lipid droplets homeostasis.
Chen W, Jin T, Xie Y, Zhong C, Gao H, Zhang L, Ju J, Cheng T, Li M, Wang H, Yang Z, Deng Q, Du Z, Liang H
British journal of pharmacology 2025 Oct;182(20):5038-5056
British journal of pharmacology 2025 Oct;182(20):5038-5056
Puerarin enhances the efficacy of carboplatin in oral squamous cell carcinoma via dual targeting.
Xie L, Zhuang Y, Lai Y, Guo J, Zhu Z, Tian H, Zhang S, Liu F
Archives of oral biology 2025 Oct;178:106360
Archives of oral biology 2025 Oct;178:106360
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
Cheng L, Li H, Xie C, Kuang K, Wan B, Chen P, Sui H, Zhao Q, Cho N, Cui R
Bioorganic chemistry 2025 Oct;165:109010
Bioorganic chemistry 2025 Oct;165:109010
Wogonin modulates macrophage polarization and inflammatory signaling through the LSD1-p65 axis to alleviate osteoarthritis.
Cai Z, Lu C, Chen D, Zhang S, Zhou J, Yu S, Wong CK, Jia Z, Jin S, Feng Y, Wu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157149
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157149
Artificial intelligence combined with affinity chromatography discover that 7-Epitaxol promotes autophagy in NSCLC cells by interacting with EGFR: Discovery of novel EGFR antagonist based on DL and CMC.
Bai H, Wu T, Lv Y, Chen W, Jiang Y, Chen F, Su P, Yu H, He L, Li Z, Han S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157127
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157127
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
He Z, Feng YD, Zhang YX, Gao X, Liu JJ, Liu S, Wu GQ
Cellular signalling 2025 Oct;134:111932
Cellular signalling 2025 Oct;134:111932
Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.
Zhu MY, Guo YJ, Zhu YQ, Wang HZ, Wang HD, Chen HY, Jiang YX, Li H, Hui H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313
Yogurt alleviates alcohol-induced hepatocyte pyroptosis and inflammation via autophagy/P62/Nrf2/ROS/NLRP3 pathway.
Guan S, Wang Y, Zhang R, Yao X, Lu S, Deng X, Lu J
Journal of dairy science 2025 Oct;108(10):10489-10503
Journal of dairy science 2025 Oct;108(10):10489-10503
Plastic tableware use, microplastic accumulation, and sperm quality: from epidemiological evidence to FOXA1/p38 mechanistic insights.
Qu J, Zeng J, Mou L, Wu X, Ha M, Liu C
Journal of nanobiotechnology 2025 Oct 9;23(1):634
Journal of nanobiotechnology 2025 Oct 9;23(1):634
Novel Isolongifolenone-Based Caprolactam Derivatives as Potential Anticancer Agents via the p53/mTOR/Autophagy Pathway.
Wang Y, Hu M, Han J, Zhao Y, Xiong B, Li P, Wang S
Molecules (Basel, Switzerland) 2025 Oct 8;30(19)
Molecules (Basel, Switzerland) 2025 Oct 8;30(19)
Uncovering the Regulatory Role of Proteins in EBSS-Induced Autophagy Using RNA-Seq Analysis.
Ruan C, Li Y, Wu R
Biology 2025 Oct 8;14(10)
Biology 2025 Oct 8;14(10)
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
Luo Y, Sun M, Chang L, He Z, Zhou X, Yuan Y, Sun H, Luo S, Huang J, Wu H, Liu W, Zhou Z, Mao Y, Ji Y, Liang T
Cell death & disease 2025 Oct 6;16(1):680
Cell death & disease 2025 Oct 6;16(1):680
Wuhu decoction regulates ROS/AMPK/mTOR pathway-mediated dendritic cells autophagy and pyroptosis for the treatment of respiratory syncytial virus-induced asthma.
Ding Y, Luo J, Deng YJ, Liu JL, Wang MQ, Hu Y
Journal of thoracic disease 2025 Oct 31;17(10):7810-7825
Journal of thoracic disease 2025 Oct 31;17(10):7810-7825
Reactive Oxygen Species (ROS) Drive Osteocyte Dysfunction in Diabetic Osteoporosis by Impairing Autophagy and Triggering Apoptosis.
Han M, Zhao M, Bai F, Wang M, Zhang B, Shi J, Liu Z
Antioxidants (Basel, Switzerland) 2025 Oct 30;14(11)
Antioxidants (Basel, Switzerland) 2025 Oct 30;14(11)
Paeoniflorin inhibits glioblastoma proliferation and promotes autophagy through the AKT/mTOR pathway.
Li H, Ouyang J, Zhang Y, Zhang Z, Sun M, Liu R, Qian C
Scientific reports 2025 Oct 29;15(1):37897
Scientific reports 2025 Oct 29;15(1):37897
Bisphenol A Disrupts Spermatogenesis via Excessive Mitophagy-Driven Ferroptosis.
Zhou Y, Duan H, Wang X, Sheng X, Qi X, Liu B, Chen X, Fang Z, Dong W, Xiao L
Environmental science & technology 2025 Oct 28;59(42):22423-22438
Environmental science & technology 2025 Oct 28;59(42):22423-22438
Combination of B-AP15 and HSP90 inhibitor tanespimycin induces ROS-mediated cytotoxicity in human lung cancer cells.
Fu W, Lu H, Yan Y, Shu C, Xu C, Chen Y, Xia Y, Chen J, Chen Y, Zou P, Cui R, Ni D
BMC pharmacology & toxicology 2025 Oct 28;26(1):177
BMC pharmacology & toxicology 2025 Oct 28;26(1):177
Miro1 protects against brain injury after CPR in rats by enhancing the effect of BMSCs on mitochondrial homeostasis.
Ma X, Shen M, Hu J, Zhu J, Wang Z, Zhou Q, Zeng M, Xu M, Qu Y, Zhou X
Stem cell research & therapy 2025 Oct 28;16(1):585
Stem cell research & therapy 2025 Oct 28;16(1):585
ITCH regulates Golgi integrity and proteotoxicity in neurodegeneration.
Xiang Q, Lu Y, Wang H, Chen H, Chen P, Zhao X, Cortes Morales L, Yang Y, Yang J, Zhang T, Wang J
Science advances 2025 Oct 24;11(43):eado4330
Science advances 2025 Oct 24;11(43):eado4330
Piezo1 exacerbates psoriasis by promoting macrophage M1 polarization and inhibits autophagy via activating PI3K/AKT signaling pathway.
Liu X, Du S, Jiang Y, Chen Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Oct 22;74(1):149
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Oct 22;74(1):149
Lipidomics Revealed the Suppression of 5-PAHSA from Human Milk on Macrophage Foam Cell Formation.
Zhang Y, Zhu S, He Y, Lei JN, Wang H, Tan C, Liu YF, Chen M, Xu YJ
Journal of agricultural and food chemistry 2025 Oct 22;73(42):27089-27098
Journal of agricultural and food chemistry 2025 Oct 22;73(42):27089-27098
HIF-1α Activates Mitophagy through BNIP3 to Inhibit IPEC-J2 Apoptosis under Heat Stress.
Li H, Bai X, Yang T, Wu C, Liu Y, Shan C, Lin R, Wen X, Cheng A
Journal of agricultural and food chemistry 2025 Oct 22;73(42):26621-26632
Journal of agricultural and food chemistry 2025 Oct 22;73(42):26621-26632
Visual Whole-Process Monitoring Dynamic Phase Separation of Autophagic Lysosomes in Alzheimer's Disease by a Lysosome-Targeted pH-Activated Fluorescence Probe.
Gao F, Lin W, Zhao T, Zhang J, Pei D, Di D, Fan Z, Yang L, Hai J
Analytical chemistry 2025 Oct 21;97(41):22518-22529
Analytical chemistry 2025 Oct 21;97(41):22518-22529
Stigmasterol improves diabetic retinopathy by inhibiting VAMP7-mediated autophagy/mitophagy.
Wang Q, Zhang P, Ji F, Li Y, Lu P
Biochemical and biophysical research communications 2025 Oct 20;785:152653
Biochemical and biophysical research communications 2025 Oct 20;785:152653
DNAJC5 promotes cisplatin resistance in epithelial ovarian cancer by autophagy induced by the BiP/IRE1α/XBP1 endoplasmic reticulum stress pathway.
Huang S, Chen L, Chen Y, Lu S, Yang B, Chen Y, Zhao W, Zhao S
Scientific reports 2025 Oct 2;15(1):34323
Scientific reports 2025 Oct 2;15(1):34323
Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling.
Feng C, Dong H, Jiang D, Gao Y, Gu X, Diao W, Zhou Y, Xu D, Li R, Wu L
International journal of molecular sciences 2025 Oct 18;26(20)
International journal of molecular sciences 2025 Oct 18;26(20)
Reversal of neurodevelopmental toxicity induced by combined exposure to the neonicotinoid insecticides acetamiprid and imidacloprid in zebrafish through targeting DRP-1: insights into mitophagy and apoptosis mechanisms.
Zhao Y, Wang S, Tan S, Wang G, Zhou H, Geng C, Li C, He Y, Shi Y, Deng Z, Chen S, Yuan Q, Wang S, Yang Y, Jiang X, He W, Wang SL, Dong H, Wang C
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126877
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126877
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Li X, Li J, Gou F, Dai Y, Zhao M, Wang D, Sun Z, Wen P, Wang J, Fan Q, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Oct 15;379:123860
Life sciences 2025 Oct 15;379:123860
GPR30-mediated the MEK/ERK signaling pathway promotes porcine oocyte maturation and development.
Duan J, Xu A, Xie J, Wang L, Lv Q, Yang J, Zhao N, Li B, Cao G
Theriogenology 2025 Oct 15;246:117537
Theriogenology 2025 Oct 15;246:117537
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence.
Fang L, Lyu L, Zhong H, Lin J, Ren P, Wang Y, Yin Y, Zhang M, Qu Y
European journal of pharmacology 2025 Oct 15;1005:178043
European journal of pharmacology 2025 Oct 15;1005:178043
Inhibition of calcium-sensing receptor by its antagonist protects dopaminergic neurons from MPTP/MPP(+)-induced neurotoxicity via regulating mitochondrial function, autophagy, and apoptosis in vivo and in vitro.
Qi H, Shen D, Wang H, Sang W, Jiang C
Neuroscience letters 2025 Oct 14;865:138351
Neuroscience letters 2025 Oct 14;865:138351
PK11007 Covalently Inhibits Thioredoxin Reductase 1 to Induce Oxidative Stress and Autophagy Impairment in NSCLC Cells.
Zhou H, Sun S, Liu H, Li T, Xu Y, Yang R, Liu H, He L, Xu W, Guan S, Xu J
Antioxidants (Basel, Switzerland) 2025 Oct 11;14(10)
Antioxidants (Basel, Switzerland) 2025 Oct 11;14(10)
Yunnan Baiyao regulates Th17/Treg cell homeostasis to inhibit periodontitis through the miR-155-5p/ATG5 pathway.
Zhao R, Chen R, An Y, Liu W, Zheng M, Ma S, Li Y, Ren X, He H
International immunopharmacology 2025 Oct 10;163:115253
International immunopharmacology 2025 Oct 10;163:115253
Vilazodone ameliorates senescence-related Alzheimer's disease like symptoms by targeting Plau to induce autophagy in senescent cells.
Sun W, Sheng X, Li R, Li P, Lin H, Gong Y
International immunopharmacology 2025 Oct 10;163:115251
International immunopharmacology 2025 Oct 10;163:115251
Endosome maturation during ER stress relies on the ubiquitin-binding domain of histone deacetylase 6.
Piscopo KM, Larson B, Christiansen AM, Perry JM, Hollien J
Molecular biology of the cell 2025 Oct 1;36(10):ar120
Molecular biology of the cell 2025 Oct 1;36(10):ar120
TRIM39-mediated deubiquitination upregulates RNF168 to evade autophagy-ferroptosis in triple-negative breast cancer.
Yao X, Shen X, Fan Y, Wang H
NPJ breast cancer 2025 Oct 1;11(1):108
NPJ breast cancer 2025 Oct 1;11(1):108
Development of an efficient mice model of cancer-associated cardiac cachexia.
Xiong S, Zheng H, Wu T, Tan J, Huang T, Shen C, Ji Y, Liu M, Wan J, Cai W
Animal models and experimental medicine 2025 Nov;8(11):1960-1970
Animal models and experimental medicine 2025 Nov;8(11):1960-1970
TRAF6 Exerts Tumor-Promoting Effects via Genetic and Autophagic Modulation in Gastric Cancer.
Zou Y, Mao Z, Xu J, Wang W, Wang Z, Dai J, Zheng R, Du M, Zhang Z
Molecular carcinogenesis 2025 Nov;64(11):1860-1871
Molecular carcinogenesis 2025 Nov;64(11):1860-1871
Neuropeptide Y1 receptor antagonist alleviated osteoarthritis by restoring chondrocyte autophagy through PI3K/AKT/mTOR signaling pathway.
Liu S, Wu J, Lin Y, Liang H, Cai Y, Wang L, Wang Z, Sang H
Journal of orthopaedic translation 2025 Nov;55:146-158
Journal of orthopaedic translation 2025 Nov;55:146-158
Cadmium-mediated autophagy increases ferroptosis of ovarian granulosa cells.
Yang L, Xu Y, Gao Y, Wan X, Chen N
Toxicology 2025 Nov;517:154224
Toxicology 2025 Nov;517:154224
(20S)-protopanaxatriol attenuates Ang II-induced renal injury via PTPN1-mediated AMPK/mTOR signaling pathway.
Zhao R, Wang Z, Liu C, Zhang L, Zhang M, Du H, Yang G, Sun H, Liu W, Yan S, Wang M
Journal of ginseng research 2025 Nov;49(6):652-662
Journal of ginseng research 2025 Nov;49(6):652-662
Autophagic damage in senescent bone marrow mesenchymal stromal cells: Impact on Piezo1 expression during osteoporosis progression.
Huang C, Chen X, Wu D, Chen J, Wang J, Li S, Hu J, Yan Z, Zhu Y, Zhang Y
International journal of biological macromolecules 2025 Nov;330(Pt 1):147928
International journal of biological macromolecules 2025 Nov;330(Pt 1):147928
Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy.
Gong B, Li F, Bai Y, Guo Y, Zhang R, Yu Y, Dong B
CNS neuroscience & therapeutics 2025 Nov;31(11):e70642
CNS neuroscience & therapeutics 2025 Nov;31(11):e70642
Caulerpa lentillifera extract alleviates the chronic diquat-induced liver oxidative damage in zebrafish (Danio rerio) in association with Nrf2 and AMPK/mTOR signaling pathway.
Lin X, Xie X, Fu Q, Liu Z, Xiao Y, Wang Y, Li H, Xie X, Wang R, Zhang Y, Song Y, Hu W
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2025 Nov;297:110276
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2025 Nov;297:110276
The V-ATPase a3 subunit deficiency affects osteoarthritis via mTOR-Mediated autophagy levels in subchondral bone.
Qiu J, Zheng X, Ye J, Yang T, Wei X, Jiang T, Gong Y, Hong Z, Chen H, Xiang J
Biochemical pharmacology 2025 Nov;241:117180
Biochemical pharmacology 2025 Nov;241:117180
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
S-palmitoylation coordinates the trafficking of ATG9A to mediate autophagy initiation.
Xia F, Li W, Wang W, Liu J, Li X, Cai J, Shan H, Cai Z, Cui J
Autophagy 2025 Nov;21(11):2422-2442
Autophagy 2025 Nov;21(11):2422-2442
SFTSV induces liver ferroptosis through m6A-related ferritinophagy.
Liu B, Tian X, Li L, Jiang N, Cheng M, Zhu J, Wu Z
Autophagy 2025 Nov;21(11):2353-2366
Autophagy 2025 Nov;21(11):2353-2366
NSUN6 Promotes Gastric Cancer Progression by Stabilizing CEBPZ mRNA in a m(5)C-Dependent Manner.
Guo J, Wu B, Wang S, Huang D, Hu Y
Applied biochemistry and biotechnology 2025 Nov;197(11):7296-7313
Applied biochemistry and biotechnology 2025 Nov;197(11):7296-7313
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF-κB signaling activation.
Qin X, Liu J, Zhao X, Wang L, Liu X, Chen Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168026
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168026
AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Nie W, Gong C, Liu Y, Yang J, Dai Q, Liao Y, Li F
Molecular immunology 2025 Nov;187:240-253
Molecular immunology 2025 Nov;187:240-253
Traditional wisdom meets modern science: The protective role of sanhuang shu'ai decoction in ulcerative colitis models.
Zhang N, Liu A, Cao M, Han Z, Guo D, Zhang S, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157163
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157163
Calcitriol/Vitamin D receptor ameliorates fructose-induced enteritis-hepatitis axis dysregulation in mice.
Yu J, Zhu H, Yu X, Liu Y, Zhang J, Jiang L, Zhang X
The Journal of nutritional biochemistry 2025 Nov;145:110017
The Journal of nutritional biochemistry 2025 Nov;145:110017
Untargeted metabolomics reveals the mechanisms of luteolin and exercise combination treatment against cognitive impairments in AD mice through modulating autophagy.
Tao X, Wang L, Gong W
The Journal of nutritional biochemistry 2025 Nov;145:110011
The Journal of nutritional biochemistry 2025 Nov;145:110011
Regulation of melanogenesis via ubiquitin-proteasome system and autophagy by 3,3,5-trimethylcyclohexyl succinate dimethylamide and tranexamic acid.
Wang J, Zha F, Lin S, Wei Y, Xuan L, Ye Z, Huang H
Journal of dermatological science 2025 Nov;120(2):61-70
Journal of dermatological science 2025 Nov;120(2):61-70
Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Wu Y, Liu H, Wang Q, Zhang T, Chen R, Yuan Q, Tong X, Yang W, Xiao Y, Yan F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e04378
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e04378
Transaldolase 1 impacts Parkinson's disease pathogenesis via metabolic reprogramming and autophagy-lysosomal pathway.
Tan Z, Hu H, Chen H, Lin Y, Zhou M, Zhang W, Xu P, Chen X
Acta neuropathologica communications 2025 Nov 4;13(1):223
Acta neuropathologica communications 2025 Nov 4;13(1):223
New perspective on postmortem meat quality changes of Esox Lucius: The role of mitophagy-mediated ferroptosis pathway.
Yan W, Li H, Yu X, Chen X, Ma L, Deng X, Zhang J
Food chemistry 2025 Nov 30;493(Pt 2):145797
Food chemistry 2025 Nov 30;493(Pt 2):145797
Liraglutide Mitigates Renal Injury in Diabetic Kidney Disease by Suppressing Podocyte Cholesterol Accumulation Through mTOR/VMP1-Regulated Autophagy.
Zou Q, Li L, Ye H, Chen Q, Li B, Wei L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71229
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71229
Autophagy-targeted intervention synergized with pegaspargase: an innovative therapeutic paradigm for pancreatic cancer.
Zhou D, Ding Z, Yin T, Huang M, Zhang X, Cao H, Wang C
Cancer cell international 2025 Nov 28;25(1):428
Cancer cell international 2025 Nov 28;25(1):428
Ferroptosis mediated by ferritinophagy is involved in liver injury caused by sepsis.
Zhang H, Li H, Liu S, Zheng J, Li P
Scientific reports 2025 Nov 27;15(1):45489
Scientific reports 2025 Nov 27;15(1):45489
Bergamot Polyphenols Reduce Hepatic Lipogenesis While Boosting Autophagy and Short-Chain Fatty Acid Production in a Murine "Cafeteria" Model of MASLD.
Riillo C, Parafati M, Crupi F, Fotschki B, Ragusa M, Di Vito A, Mignogna C, Mollace V, Janda E
Nutrients 2025 Nov 25;17(23)
Nutrients 2025 Nov 25;17(23)
Pulchinenoside E2: A dual-functional STAT3 and autophagy inhibitor with potent anti-metastatic activity in triple-negative breast cancer.
Zheng D, Shu J, Gao B, Yu H, Liu K, Zheng M, Liu X, Chen G, Lin Y, Li Q, Sun Y, Zheng Y, Li B, Yang X, Wang K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157485
Semen Ziziphi Spinosae affects circadian rhythm of the cAMP signaling pathway by BMAL1-clockophagy to improve sleep disorders in depression.
Zhang Y, Feng Y, Lu Y, Ying Y, Wang D, Ying X, Pang Z, Zhang W, Liu Z, Zheng W, Yang F, Xu Q, Chen S, Zhu Y, Yu J, Zhu Z, Sun H, He S, Zhang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157483
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157483
The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.
Xu Z, Si J, Liang A, Zhang Y, Gong J, Li G, Zhong Y, Yu M, Feng R, Li X, Chang J, Wang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304
Hyperoside Promotes Mitochondrial Autophagy Through the miR-361-5p/PI3K/Akt/mTOR Signaling Pathway, Thereby Improving UVB-Induced Photoaging.
Yang D, Le J, Xiao S, Cui Y, Zhu W, Otsuki K, Li W, Xu J, Feng F, Zhang J
Antioxidants (Basel, Switzerland) 2025 Nov 25;14(12)
Antioxidants (Basel, Switzerland) 2025 Nov 25;14(12)
5-Aminoimidazole-4-carboxamide-1- β -d-ribofuranoside ameliorates lipotoxicity through enhanced reticulophagy in HepG2 cells.
Krishnan U A, Venkataraman AC, Ramachandran V
Biotechnology and applied biochemistry 2025 Nov 21;
Biotechnology and applied biochemistry 2025 Nov 21;
[Astragaloside IV alleviates D-GAL-induced endothelial cell senescence by promoting mitochondrial autophagy via inhibiting the PINK1/Parkin pathway].
Yi M, Luo Y, Wu L, Wu Z, Jiang C, Chen S, Ke X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Nov 20;45(11):2427-2437
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Nov 20;45(11):2427-2437
Hyperosmolarity-Induced Oxidative Stress Leads to Senescence in Human Corneal Epithelial Cells (HCEPC) via DNA Damage, Metabolic Disturbance and Mitophagy Decline.
Zhang Y, Fan T
Antioxidants (Basel, Switzerland) 2025 Nov 19;14(11)
Antioxidants (Basel, Switzerland) 2025 Nov 19;14(11)
Ribosome dysregulation and intervention in age-related infertility.
Li J, Wang H, Zhu P, Chen H, Zuo H, Liu C, Liu L, Ye X, Feng G, Wu Y, Liu Q, Yang T, Keefe DL, Bai X, Shang W, Wu X, Liu L
Cell reports. Medicine 2025 Nov 18;6(11):102424
Cell reports. Medicine 2025 Nov 18;6(11):102424
BPP disrupts spermatogenesis via mitochondrial-ER stress-mediated autophagic flux blockade in mice.
Zhang S, Qin D, Lin Z, Wang S, Wang L, Wang J, Zhang X, Sun S, Ding Q, Chen X, Li J, Liu J, Ma Z, Wu X, Liu Y
Ecotoxicology and environmental safety 2025 Nov 15;307:119392
Ecotoxicology and environmental safety 2025 Nov 15;307:119392
The EGR1/miR-199a-3p/mTOR axis: A crucial pathway in the amplification of myocardial damage under intermittent hypoxic conditions.
Dong N, Yue H
European journal of pharmacology 2025 Nov 15;1007:178251
European journal of pharmacology 2025 Nov 15;1007:178251
NCOA4-mediated ferroptosis conducive to EMT inhibition in colorectal cancer cells was achieved through the PI3K/AKT/mTOR pathway.
Fu Y, Zhao Q, Li Y, Sun Y, He B, Li C, Zhang W, Yin Y, Li C
Scientific reports 2025 Nov 11;15(1):39542
Scientific reports 2025 Nov 11;15(1):39542
Neuroglobin-promoted autophagy inhibits the proliferation, migration and invasion of human glioblastoma cells through the EGFR/PI3K/AKT/mTOR signaling pathway.
Li L, Zhang H, Li W, Yuan Z, Zhao W, Luo Z
Journal of translational medicine 2025 Nov 10;23(1):1248
Journal of translational medicine 2025 Nov 10;23(1):1248
Gallic Acid Alleviates Cerebral Ischemia-reperfusion Injury in Mice by Mediating Microglial Polarization Through the NLRP3/mTOR Axis.
Hua W, Xu H, Chen R, Zhang H, Zhang Y, Zhang X, Zhang Y, Liu J, Zhang L, Yang P
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Nov 10;20(1):101
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Nov 10;20(1):101
CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.
Huang T, Tang Y, Su Q, Su C, Wang J, Fu L, Tang Y
Cell death & disease 2025 Nov 10;16(1):815
Cell death & disease 2025 Nov 10;16(1):815
Nrf2 alleviates excessive deposition of extracellular matrix in mammary fibrosis through TGF/Smad and ROS signals.
Kan X, Xu P, Yu M, Guo W, Cao Y, Hu G, Liu J, Fu S, Bi J
Scientific reports 2025 Nov 10;15(1):39252
Scientific reports 2025 Nov 10;15(1):39252
Pioglitazone reduces hepatic α-1 antitrypsin accumulation through autophagy and AMPK activation in α-1 antitrypsin-deficient mice.
Lu Y, Oshins R, Maptue NR, Shen Q, Khemtong C, Cusi K, Brantly M, Khodayari N
American journal of physiology. Gastrointestinal and liver physiology 2025 Nov 1;329(5):G585-G596
American journal of physiology. Gastrointestinal and liver physiology 2025 Nov 1;329(5):G585-G596
Neuromuscular electrical stimulation alleviates stroke-related sarcopenia by promoting satellite cells myogenic differentiation via AMPK-ULK1-Autophagy axis.
Xiang X, Huang L, Luo W, Qin L, Bian M, Chen W, Han G, Wang N, Mo G, Zhang C, Zhang Y, Yang H, Lu S, Zhang J, Fu T
Journal of orthopaedic translation 2025 May;52:249-264
Journal of orthopaedic translation 2025 May;52:249-264
6PPD induces apoptosis and autophagy in SH-SY5Y cells via ROS-mediated PI3K/AKT/mTOR pathway: In vitro and in silico approaches.
Wang Z, Wang S, Liu Y, Wang X, Li W, Qi H, You H
Toxicology 2025 May;513:154091
Toxicology 2025 May;513:154091
Daidzein Attenuates Cadmium-Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague-Dawley Rats.
Wen S, Zhao Y, Wang L, Yuan Y
Journal of biochemical and molecular toxicology 2025 May;39(5):e70299
Journal of biochemical and molecular toxicology 2025 May;39(5):e70299
Aerobic exercise improves astrocyte mitochondrial quality and transfer to neurons in a mouse model of Alzheimer's disease.
Cai J, Chen Y, She Y, He X, Feng H, Sun H, Yin M, Gao J, Sheng C, Li Q, Xiao M
Brain pathology (Zurich, Switzerland) 2025 May;35(3):e13316
Brain pathology (Zurich, Switzerland) 2025 May;35(3):e13316
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.
Li R, Li Q, Yang C, Liu H, Xiao Y, Yang P, Gong G, Wu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 May;34(5):108280
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 May;34(5):108280
Activation of sigma 1 receptor attenuates doxorubicin-induced cardiotoxicity by alleviating oxidative stress, mitochondria dysfunction, ER stress-related apoptosis, and autophagy impairment.
Al-Maamari A, Sultan M, Wu S, Zhang T, Wang C, Han B, Duan Y, Ding SS, Chen N, Zhang H, Sun F, Chen X, Yu D, Su S
International journal of biological macromolecules 2025 May;310(Pt 4):143549
International journal of biological macromolecules 2025 May;310(Pt 4):143549
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Zhang L, Wu G, Yao J, Wang D, Gao F, Qian Z
International journal of biological macromolecules 2025 May;309(Pt 4):143143
International journal of biological macromolecules 2025 May;309(Pt 4):143143
Lactoferrin ameliorates cognitive impairment in D-galactose-induced aging mice by regulating the PI3K/Akt/mTOR signaling pathway and the microbiome-gut-brain axis.
Wang M, Wang Y, Wang X, Qiu Y, Li C, Li H, Li H, Yu J
International journal of biological macromolecules 2025 May;309(Pt 4):143033
International journal of biological macromolecules 2025 May;309(Pt 4):143033
NSUN2-mediated m5C modification of circFAM190B promotes lung cancer progression by inhibiting cellular autophagy.
Chen S, Cai D, Zhao Q, Wu J, Zhou X, Xu H, Li X, Zhang R, Peng W, Li G, Nan A
International journal of biological macromolecules 2025 May;306(Pt 3):141528
International journal of biological macromolecules 2025 May;306(Pt 3):141528
A novel nuclear receptor NR1D1 suppresses HSD17B12 transcription to regulate granulosa cell apoptosis and autophagy via the AMPK pathway in sheep.
Cai Y, Xu H, Deng K, Yang H, Zhao B, Zhang C, Li S, Wei Z, Wang Z, Wang F, Zhang Y
International journal of biological macromolecules 2025 May;306(Pt 1):141271
International journal of biological macromolecules 2025 May;306(Pt 1):141271
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway.
Guo C, Zhang T, Du L, Yu K, Zeng S, Li M, Chi Y, Li Y
Biochemical pharmacology 2025 May;235:116821
Biochemical pharmacology 2025 May;235:116821
EPIC-1042 alleviates cerebral ischemic/reperfusion injury through TAX1BP1-induced mitophagy.
Ju J, Cheng C, Cui L, Hong B, Zhan Q, Wang Q, Cui X, Su D, Huang Y, Kang C
Free radical biology & medicine 2025 May;232:367-381
Free radical biology & medicine 2025 May;232:367-381
Methionine is an essential amino acid in doxorubicin-induced cardiotoxicity through modulating mitophagy.
Xin Y, Zhang Y, Yuan Z, Li S
Free radical biology & medicine 2025 May;232:28-39
Free radical biology & medicine 2025 May;232:28-39
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Dong RF, Qin CJ, Yin Y, Han LL, Xiao CM, Wang KD, Wei RY, Xia YZ, Kong LY
British journal of pharmacology 2025 May;182(10):2287-2309
British journal of pharmacology 2025 May;182(10):2287-2309
Deubiquitinase USP13 alleviates doxorubicin-induced cardiotoxicity through promoting the autophagy-mediated degradation of STING.
Lin L, Han J, Xu D, Fang Z, Ye B, Qian J, Han X, Min J, Long X, Wu G, Liang G
Acta pharmaceutica Sinica. B 2025 May;15(5):2545-2558
Acta pharmaceutica Sinica. B 2025 May;15(5):2545-2558
Toosendanin-induced liver damage through irreparable DNA damage and autophagy flow blockade.
Lin Y, Zhang J, Gao X, Wu Z, Yang L, Tian K, Lv X, Li J, Chen K, Zhang Y, Hu H, Zhu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156586
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156586
Fluoxetine-Conjugated Platinum(IV) Prodrugs Targeting eEF2K and Conquering Multidrug Resistance against Triple-Negative Breast Cancer.
Wang JQ, Liu XM, Zhu ZS, Li Z, Xie CZ, Qiao X, Feng YK, Xu JY
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Journal of medicinal chemistry 2025 May 8;68(9):9661-9680
Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism.
Liu P, Hu P, Jin M, Sun W, Wu J, Tang Y, Shi D, Xie T, Tong Y, Huang L, Zhang D, Zheng H, Xu X, He H
BMC microbiology 2025 May 8;25(1):280
BMC microbiology 2025 May 8;25(1):280
6-shogaol alleviates excessive neuronal autophagy and calcium overload following cerebral ischemia-reperfusion injury by inhibiting the expression of DAPK1.
Rao O, Li S, Zhu N, Zhou H, Tao J, Li Y, Liu Y
Neuroscience 2025 May 7;573:74-84
Neuroscience 2025 May 7;573:74-84
Rilmenidine attenuates intracerebral hemorrhage by regulating autophagy flux and apoptosis via the HO-1/Fe(2+)/ERK pathway.
Hua Q, Lu M, Li Z, Song P, Gao L, Zhou L, Zhang J, Cai Q
Neuroscience 2025 May 7;573:382-398
Neuroscience 2025 May 7;573:382-398
Conjugation with the XJB peptide enhanced neuroprotective effect of honokiol via SIRT3 modulation.
Liu G, Zhang T, Qian S, Zhang X, Lou H, Fan P
European journal of medicinal chemistry 2025 May 5;289:117460
European journal of medicinal chemistry 2025 May 5;289:117460
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Jiang S, Bu S, Kang X, Dong Y, Chen L, Yuan L, Shi M, Du M, Liang M, Huang K, Yang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
Mitochondrial Genome-Encoded lncND5 Regulates Mitophagy in Hypoxic Pulmonary Artery Smooth Muscle Cell.
Bai J, He S, Wang X, Zhang L, Ma C, Gao D, Yuan H, Mei J, Guan X, Yu H, Wan K, Zhu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70618
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70618
Enhanced SIRT1-TFEB Interaction Promotes Lysosome Biogenesis and Autophagy by Reducing TFEB Acetylation: Revealing the Enterotoxicity Disparity of Deoxynivalenol and T-2 Toxin.
Xu Q, Lin R, Jiang T, Deng L, Wu Y, Yuan Q, Qi X, Mu P, Jiang J, Deng Y, Wen J
Journal of agricultural and food chemistry 2025 May 28;73(21):12993-13005
Journal of agricultural and food chemistry 2025 May 28;73(21):12993-13005
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
Zhang X, Wang L, Huang L, Cao G, Huang C, Duan Y, Lyu W
Journal of ethnopharmacology 2025 May 28;348:119793
Journal of ethnopharmacology 2025 May 28;348:119793
An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection.
Walter Z, Li M, Molho M, Berish L, Isopi A, O'Mara M, Dittmar M, Nwaezeapu C, Richards A, McCullagh M, Krogan NJ, Cherry S, Johnson JR, Ramage H
Cell reports 2025 May 27;44(5):115728
Cell reports 2025 May 27;44(5):115728
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Yang K, Zhang X, Yang K, Liu S, Zhang J, Fu Y, Liu T, Wu K, Li J, Liu C, Huang Q, Qu K
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
RAB18 deficiency disrupts lipid metabolism and autophagy in mice.
Zhang LW, Han YQ, Yang Y, Li YJ, Ma YX, Ming SL
Biochemical and biophysical research communications 2025 May 26;760:151673
Biochemical and biophysical research communications 2025 May 26;760:151673
NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma.
Gong B, Liu Y, Yan W, Cheng C, Yang H, Huang J, Liu Q, Liu Y, Guo J, Deng X, Zhou B, Zheng D, Liu X, Liu Z, Fang W
Molecular cancer 2025 May 26;24(1):152
Molecular cancer 2025 May 26;24(1):152
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.
Zheng Y, Lin J, Wan G, Gu X, Ma J
Biology direct 2025 May 26;20(1):65
Biology direct 2025 May 26;20(1):65
CIRBP Enhances the Function of Yak Cumulus Cells by Activating AMPK/mTOR-Mediated Mitophagy.
Zhang R, Cui Y, Pan Y, Wang M, Yu S, Xu R, Ma W, Wang J, Zhong D, Jiao Z
Biomolecules 2025 May 24;15(6)
Biomolecules 2025 May 24;15(6)
Chicken interferon-induced transmembrane proteins inhibit Newcastle disease virus infection by affecting viral entry and W protein expression.
Chen J, Li P, Zou W, Li J, Jiang Y, Li L, Hao P, Gao Z, Hao J, Shi X, Li C
Veterinary research 2025 May 21;56(1):104
Veterinary research 2025 May 21;56(1):104
Ultrasound Visualization of Spatiotemporal Autophagy-Regulated Nanodroplets for Amplifying ICB in Melanoma via Remodeling Tumor Inflammatory Microenvironment.
Wu N, Zhang Q, Tang R, Deng L, Cao Y, Fu B, Dong H, Huang Z, Wan L, He H, Lin Y, Liu J, Xia C, Li P
ACS applied materials & interfaces 2025 May 21;17(20):29364-29378
ACS applied materials & interfaces 2025 May 21;17(20):29364-29378
Heat shock protein A1 inhibits the replication of foot-and-mouth disease virus by degrading viral RNA polymerase 3D through chaperone-mediated autophagy.
Ren M, Zhou H, Wu J-e, Wang J-n, Wang X, Abdullah SW, Guo H, Sun S
Journal of virology 2025 May 20;99(5):e0016825
Journal of virology 2025 May 20;99(5):e0016825
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Wang Z, Yu C, Xie G, Tao K, Yin Z, Lv Q
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Lysionotin promoted apoptosis of hepatocellular carcinoma cells via inducing autophagy.
Wang X, Zhong W, Wang Q, Song P, Lin X, Li B, Yin Y, Yang C, Li M
Discover oncology 2025 May 16;16(1):788
Discover oncology 2025 May 16;16(1):788
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis.
Zhang HJ, Zhao Q, Zhang M, Yang LL, Abiti J, Han MM, Gao YP, Lu JT, Wang JN, Ji MY, Zhang X, Wang W, Qiu LL, Wang XY, Wang TY, Jia YL
ACS synthetic biology 2025 May 16;14(5):1802-1812
ACS synthetic biology 2025 May 16;14(5):1802-1812
A therapeutic strategy integrating ultrasound-guided microwave ablation with nanocomposite hydrogels to enhance autophagy and suppress tumor growth in hepatocellular carcinoma.
Duan Y, Ding L, Meng X, Lin J, Fu H, Zhu Y, Qiu Y, Cao J, Hu J, Dong Y, Duan Y, Chen J
Acta biomaterialia 2025 May 15;198:413-427
Acta biomaterialia 2025 May 15;198:413-427
Lactoferrin Alleviates LPS-Induced Oxidative Stress and Necroptosis in Liver by Promoting Mitophagy.
Guan S, Lu S, Zhang R, Wang Y, Yao X, Deng X, Lu J
Journal of agricultural and food chemistry 2025 May 14;73(19):11948-11959
Journal of agricultural and food chemistry 2025 May 14;73(19):11948-11959
IGF2BP3-mediated m(6)A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.
Geng Q, Jiao Y, Diao W, Xu J, Wang Z, Wang X, Wang Z, Zhao L, Yang L, Wang Y, Deng T, Wang B, Xiao C
Bone research 2025 May 12;13(1):51
Bone research 2025 May 12;13(1):51
Hsp90 and HIF-1α regulate mitophagy by promoting BNIP3 expression in renal ischemia-reperfusion injury.
Dong Q, Li X, Cheng K
Transplant immunology 2025 Mar;89:102177
Transplant immunology 2025 Mar;89:102177
Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat via enhancement of METTL14-mediated m6A methylation of Aldh1l1.
Wu L, Luo Z, Luo F, Huang T, Cen Y, Rao G, Zhao Z, Ou R, Zhou M
Free radical research 2025 Mar;59(3):274-288
Free radical research 2025 Mar;59(3):274-288
Protein regulator of cytokinesis 1 regulates autophagy in hepatitis B virus‑associated liver cancer development.
Huang J, Cheng X, Wang C, Gong F
Oncology reports 2025 Mar;53(3)
Oncology reports 2025 Mar;53(3)
Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin-Driven TFEB Nuclear Translocation.
Wang P, Li J, Li CG, Zhou X, Chen X, Zhu M, Wang H
Clinical and experimental pharmacology & physiology 2025 Mar;52(3):e70010
Clinical and experimental pharmacology & physiology 2025 Mar;52(3):e70010
Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target.
Zuo X, Zhao R, Wu M, Wang Y, Wang S, Tang K, Wang Y, Chen J, Yan X, Cao Y, Li T
Nature aging 2025 Mar;5(3):419-436
Nature aging 2025 Mar;5(3):419-436
JAK2/ULK1 axis promotes cervical cancer progression by autophagy induction and SRPK1 phosphorylation.
Duan Q, Wang W, Xiong H, Xiao J, Xiao H, Zhu F, Lu H
Oncogene 2025 Mar;44(9):587-600
Oncogene 2025 Mar;44(9):587-600
Investigating the role of IL-6 in the pathogenesis of systemic lupus erythematosus: Insights from bone marrow mesenchymal stem cells.
Zhang Z, Zhu S, Li Q, Wei S, Yin L, Zhu J, Yang S, Zhang W, Lai K
Lupus 2025 Mar;34(3):225-233
Lupus 2025 Mar;34(3):225-233
Eravacycline improves the efficacy of anti-PD1 immunotherapy via AP1/CCL5 mediated M1 macrophage polarization in melanoma.
Liu N, Yan M, Lu C, Tao Q, Wu J, Zhou Z, Chen J, Chen X, Peng C
Biomaterials 2025 Mar;314:122815
Biomaterials 2025 Mar;314:122815
DNLA Delayed the Appearance of Learning and Memory Impairment of APP/PS1 Mice: Involvement of mTOR/TFEB/v-ATPase Signaling Pathway.
Wu Y, Liu X, Luo G, Li Q, Guo B, Li L, Nie J
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
CNS neuroscience & therapeutics 2025 Mar;31(3):e70300
Bisdemethoxycurcumin mitigates traumatic brain injury in rats by modulating autophagy and oxidative stress via heat shock protein 90 alpha family class A member 1-mediated nuclear translocation of transcription factor EB.
Xu Y, Peng LS, Xiao CQ, Zhou Y, Wang QS, Fu H
Brain research bulletin 2025 Mar;222:111221
Brain research bulletin 2025 Mar;222:111221
Oral exposure to nanoplastics altered lipid profiles in mouse intestine.
Luo S, Zhao X, Wang Y, Jiang M, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Mar;197:115304
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Mar;197:115304
Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma.
Li O, An K, Wang H, Li X, Wang Y, Huang L, Du Y, Qin N, Dong J, Wei J, Sun R, Shi Y, Guo Y, Sun X, Yang Y, Yang YG, Kan Q, Tian X
Clinical and translational medicine 2025 Mar;15(3):e70270
Clinical and translational medicine 2025 Mar;15(3):e70270
PIWI-interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation.
Li SS, Guo M, Long Y, Cai Y, Zhao Y, Huang S, Yang H, Fan Y, Chen X, Jin X
Clinical and translational medicine 2025 Mar;15(3):e70260
Clinical and translational medicine 2025 Mar;15(3):e70260
Oxymatrine alleviates ALD-induced cardiac hypertrophy by regulating autophagy via activation Nrf2/SIRT3 signaling pathway.
Lu D, Wu S, Wang X, Zhang J, Xu Y, Tao L, Shen X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156389
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156389
HMGB1 secretion by resveratrol in NSCLC: A pathway to ferroptosis-mediated platelet activation suppression.
Zhang Y, Bao S, Zeng J, Liu J, Li X, Zhang B, Wang H, Cheng Y, Zhang H, Xia W, Zu L, Xu X, Xu S, Song Z
Cellular signalling 2025 Mar;127:111607
Cellular signalling 2025 Mar;127:111607
Wnt5a alleviates the symptoms of PCOS by modulating PI3K/AKT/mTOR pathway-mediated autophagy in granulosa cells.
Ma Y, Ma Y, Li P, Ma F, Yu M, Xu J, Yang Y
Cellular signalling 2025 Mar;127:111575
Cellular signalling 2025 Mar;127:111575
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Shi M, Li X, Guo Y, Zhang Y, Xu J, Yan L, Liu R, Wang H, Tang S, Zhao Y, Li Z, Feng Y, Ren D, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Targeting TTK Inhibits Tumorigenesis of T-Cell Lymphoma Through Dephosphorylating p38α and Activating AMPK/mTOR Pathway.
Liu B, Lu T, Ding M, Zhou X, Jiang Y, Shang J, Sun W, Hu S, Wang X, Zhou X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2413990
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2413990
Polysaccharide alleviates neurodegeneration and behavioral deficit by enhancing mitochondrial autophagy in chronic methamphetamine mice.
Yang H, Wang Y, Liu S, Zhang S, Chen Y, Ding J, Chen S, Zhu F, Xia B, Luo P, Liu Y
Neurotoxicology 2025 Mar;107:53-61
Neurotoxicology 2025 Mar;107:53-61
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Zhang S, Gu M, Yin H, Pan S, Xie H, Chen W, Gul S, Zhao Y, Wang Z, Zheng W, You Y, You B
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Irisin promotes autophagy and attenuates NLRP3 inflammasome activation in Parkinson's disease.
Zhu M, Peng Q, Li S, Zhang G, Zhang Z
International immunopharmacology 2025 Mar 6;149:114201
International immunopharmacology 2025 Mar 6;149:114201
The CRISPR/Cas9-Mediated Knockout of VgrG2 in Wild Pathogenic E. coli to Alleviate the Effects on Cell Damage and Autophagy.
Pan TL, Cha JL, Wang H, Zhang JS, Xiao JL, Shen J, Zhou M, Li Y, Ma JZ, Zhao KY, Zhang YK, Xiao P, Gao H
Veterinary sciences 2025 Mar 5;12(3)
Veterinary sciences 2025 Mar 5;12(3)
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Peng X, Yang R, Wang C, Peng W, Zhao Z, Shi S, Cai Q, He B, Wang L, Yu F, Wang X, Tao Y
Cancer letters 2025 Mar 31;613:217503
Cancer letters 2025 Mar 31;613:217503
Programmed enhancement of endogenous iron-mediated lysosomal membrane permeabilization for tumor ferroptosis/pyroptosis dual-induction.
Zhu L, Hu J, Wu X, Zhang J, Xu X, Huang X, Tian B, Zhao CX, Du Y, Wu L
Nature communications 2025 Mar 28;16(1):3017
Nature communications 2025 Mar 28;16(1):3017
Umbelliferone attenuates calcium oxalate crystal-induced renal injury and inflammation by attenuating autophagy through the PI3K/AKT pathway.
Xu Y, Liang H, Xia K, Yao J, Chen Y, Hou B, Hao Z
International immunopharmacology 2025 Mar 26;150:114250
International immunopharmacology 2025 Mar 26;150:114250
Effects of Melatonin on H(2)O(2)-Induced Oxidative Damage of the Granulosa Cells in Hen Ovarian Follicles.
Wang S, Ou Y, Cao S, Sun X, Qin N, Liswaniso S, Xu R
Genes 2025 Mar 22;16(4)
Genes 2025 Mar 22;16(4)
CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.
Li YY, Meng FL, Zhou SY, Du JM, Li WJ, Liu QY, Wu L, Zhao MM, Jin Y, Zhang QY, Li Y, Su GH
Scientific reports 2025 Mar 22;15(1):9985
Scientific reports 2025 Mar 22;15(1):9985
Rapamycin mitigates neurotoxicity of fluoride and aluminum by activating autophagy through the AMPK/mTOR/ULK1 pathway in hippocampal neurons and NG108-15 cells.
Tao D, Xia Y, Liao Q, Yang X, Zhang L, Xie C
Scientific reports 2025 Mar 21;15(1):9801
Scientific reports 2025 Mar 21;15(1):9801
SAP30, a novel autophagy regulatory gene in neuroblastoma.
Pathania AS, Murugan A, Zahid A, Chava H, Coulter DW, Calin GA, Challagundla KB
Molecular therapy. Oncology 2025 Mar 20;33(1):200916
Molecular therapy. Oncology 2025 Mar 20;33(1):200916
Dietary phytosterol supplementation mitigates renal fibrosis via activating mitophagy and modulating the gut microbiota.
Yang F, Gao Y, Xie S, Yang W, Wang Q, Ye W, Sun L, Zhou J, Feng X
Food & function 2025 Mar 17;16(6):2316-2334
Food & function 2025 Mar 17;16(6):2316-2334
Sulfur dioxide increases testosterone biosynthesis by activating ERK1/2 pathway and disrupting autophagy in Leydig cells.
Li X, Shi Y, Liu S, Feng Z, Xiao H, Li R, Li Z, Zhang X, Han Y, Wang J, Liang C, Bai J, Zhang J
Journal of hazardous materials 2025 Mar 15;486:137001
Journal of hazardous materials 2025 Mar 15;486:137001
Angiopoietin-2 regulates the phenotypic switch of vascular smooth muscle cells.
Gan X, Lu S, Ning F, Ye Y, Guo K, Chen M, Ou D, Lu Q, Lash GE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70434
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70434
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.
Chiu HW, Chu CW, Huang CC, Chia ZC, Wang YL, Lee YH
Environmental pollution (Barking, Essex : 1987) 2025 Mar 15;369:125850
Environmental pollution (Barking, Essex : 1987) 2025 Mar 15;369:125850
HTLV-1 Tax induces PINK1-Parkin-dependent mitophagy to mitigate activation of the cGAS-STING pathway.
Mohanty S, Suklabaidya S, Mnatsakanyan N, Jacobson S, Harhaj EW
bioRxiv : the preprint server for biology 2025 Mar 15;
bioRxiv : the preprint server for biology 2025 Mar 15;
Lactobacillus plantarum SMUM211204 Exopolysaccharides Have Tumor-Suppressive Effects on Colorectal Cancer by Regulating Autophagy via the mTOR Pathway.
Wang Z, Chen H, Xiong S, Chen X, Gao X, Huang P, Zou J, Cao H
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5931-5946
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5931-5946
Alpha-Synuclein Inhibits the Secretion of Extracellular Vesicles through Disruptions in YKT6 Lipidation.
Tsunemi T, Ishiguro Y, Yoroisaka A, Feng D, Shimada T, Niiyama S, Sasazawa Y, Ishikawa K, Akamatsu W, Hattori N
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Mar 12;45(11)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Mar 12;45(11)
Triclosan Caused Oocyte Meiotic Arrest by Modulating Oxidative Stress, Organelle Dysfunctions, Autophagy, and Apoptosis in Pigs.
Zhao N, Xu A, Yang J, Zhao J, Xie J, Li B, Duan J, Cao G
Animals : an open access journal from MDPI 2025 Mar 12;15(6)
Animals : an open access journal from MDPI 2025 Mar 12;15(6)
Glycidol induces necroptosis and inflammation through autophagy-necrosome pathway in renal cell and mice.
Lu J, Wei H, Yao X, Chen Y, Liu M, Guan S
The Science of the total environment 2025 Mar 10;968:178852
The Science of the total environment 2025 Mar 10;968:178852
Wnt1 oversees microglial activation by the Wnt/LRP5/6 receptor signaling pathway during lipopolysaccharide-mediated toxicity.
Qing W, Hao X, Xuan S, Zhihui R, Jinzhi G
Molecular biology reports 2025 Mar 1;52(1):273
Molecular biology reports 2025 Mar 1;52(1):273
Antimony-induced hippocampal neuronal impairment through ferroptosis activation from NCOA4-mediated ferritinophagy.
Yu S, Qin Z, Chen Y, Wang F, Li Z, Huang R, Gao Z, Qu Y, Xue P, Luo Y, Wang X, Zhao X
Chemico-biological interactions 2025 Mar 1;409:111415
Chemico-biological interactions 2025 Mar 1;409:111415
Inhibition of autophagy attenuates cognitive decline and mitochondrial dysfunction in an Alzheimer's disease mouse model with chronic cerebral hypoperfusion.
Yang Q, Chen T, Li S, Yang C, Zheng X, Mao S, Liu N, Mo S, Li D, Yang M, Lu Z, Tang L, Huang X, Liu X, Jian C, Yin Y, Shang J
Brain research 2025 Mar 1;1850:149416
Brain research 2025 Mar 1;1850:149416
Modification of RNF183 via m6A Methylation Mediates Podocyte Dysfunction in Diabetic Nephropathy by Regulating PKM2 Ubiquitination and Degradation.
Guo D, Pang Y, Wang W, Feng Y, Wang L, Sun Y, Hao J, Li F, Zhao S
Cells 2025 Mar 1;14(5)
Cells 2025 Mar 1;14(5)
GLA deficiency causes cardiac hypertrophy via enhanced autophagy.
Ou W, Li X, Tang K, Ding L, Sun T, Li Q, Li T
Science China. Life sciences 2025 Jun;68(6):1689-1702
Science China. Life sciences 2025 Jun;68(6):1689-1702
PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
Wang A, Zhang F, Zhang W, Gong J, Sun X
Experimental neurology 2025 Jun;388:115218
Experimental neurology 2025 Jun;388:115218
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Liu W, Zhu Y, Ye W, Xiong J, Wang H, Gao Y, Huang S, Zhang Y, Zhou X, Zhou X, Ge X, Cai W, Zheng X
Cell death and differentiation 2025 Jun;32(6):1041-1057
Cell death and differentiation 2025 Jun;32(6):1041-1057
Cholesterol-dependent Nsp5-endosomes co-trafficking to lysosomes facilitates porcine reproductive and respiratory syndrome virus replication by activating autophagy.
Dong H, Pei Q, Ren J, Zhang Y, Wei X, Shen A, Lu Y, Zhang Z, Du Y, Zhuang G, Zhang A, Duan H
Veterinary microbiology 2025 Jun;305:110507
Veterinary microbiology 2025 Jun;305:110507
Melatonin attenuates inflammatory bone loss by alleviating mitophagy and lactate production.
Lin Z, Gu Y, Liu Y, Chen Z, Fang S, Wang Z, Liu Z, Lin Q, Hu Y, Jiang N, Yu B, Liu G
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1351-1371
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1351-1371
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Li W, Yin Q, Qiu Y, Liu J, Wang J, Li C, Zhang D, Zhang P, Lv H, Lv Y, Wang Y
Cancer genetics 2025 Jun;294-295:156-170
Cancer genetics 2025 Jun;294-295:156-170
A bacterial RING ubiquitin ligase triggering stepwise degradation of BRISC via TOLLIP-mediated selective autophagy manipulates host inflammatory response.
Pan X, Sun Y, Liu J, Chen R, Zhang Z, Li C, Yao H, Ma J
Autophagy 2025 Jun;21(6):1353-1372
Autophagy 2025 Jun;21(6):1353-1372
Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.
Wu Y, Zhou H, Liu H, Hu J, Sun Y, Yan W, Tong C, Kong Y, Liu B
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3305-3320
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3305-3320
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Wang Y, Jiang L, Tian JJ, Zhu LL, Dai HJ, Guo C, Zhou LY, Wang L, Lu Y, Zhang Y
Neurochemical research 2025 Jun 5;50(3):180
Neurochemical research 2025 Jun 5;50(3):180
An erythroid-biased FOS(hi) hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia.
Liu W, Zhang X, Liu J, Pu L, Ai L, Xu H, Wang G, Wang D, Song X, Zhang Y, Zhang L, Gao J, Cheng X, Wang X, Tong J, Xie X, Dong F, Zhang Y, Zhu P, Chen Z, Wu P, Shi L
Cell stem cell 2025 Jun 5;32(6):935-951.e7
Cell stem cell 2025 Jun 5;32(6):935-951.e7
TGF-β1 induces autophagy and mediates the effect on macrophages differentiation in primary liver cancer.
Liu C, Li M, Liu L, Xu Q, Zheng L, Wu C, Ren J, Zhang T, Wang H, Lin Z
International immunopharmacology 2025 Jun 5;157:114799
International immunopharmacology 2025 Jun 5;157:114799
Identification of molecular subtypes and a prognostic risk model based on mitochondrial dynamic related genes in clear cell renal cell carcinoma.
Yang K, Yang K, Lei Z, Wu K, Li J, Peng Q, Liu C, Qu K, Lin T
Biochemical and biophysical research communications 2025 Jun 30;767:151911
Biochemical and biophysical research communications 2025 Jun 30;767:151911
Proteomics based discovery of Salvia miltiorrhiza Bunge treating Parkinson's disease through the PINK1/Parkin pathway.
Xu D, ShenTu C, Zong C, Fu W, Ling J, Shao P, Liu X, Chen Y, Xu T
Journal of ethnopharmacology 2025 Jun 26;350:120079
Journal of ethnopharmacology 2025 Jun 26;350:120079
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy.
Xiang D, Zhang X, Xue X, Liang H, Meng J, Zhao S, Yang J, Zhou Y, Hu Y, Xu L, Shi M, Zhang J, Wang M, Chen J, Han Y
Journal of ethnopharmacology 2025 Jun 26;350:120055
Journal of ethnopharmacology 2025 Jun 26;350:120055
5'-tiRNA-Lys maintains intestinal epithelial homeostasis by EWSR1-dependent suppression of miR-125a and autophagy activation.
Xu N, Huang J, Wang Y, Liu Y, Jiang Y, Zhou W, Sheng J, Zhang L
Acta biochimica et biophysica Sinica 2025 Jun 23;58(2):290-302
Acta biochimica et biophysica Sinica 2025 Jun 23;58(2):290-302
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer.
Zhang Y, Yang E, Zhang X, Zhang Z, Huang G, Tang B, Chen C, Lai L, Pei Z, Zhang Y, Wang Z
Journal of cancer research and clinical oncology 2025 Jun 21;151(6):194
Journal of cancer research and clinical oncology 2025 Jun 21;151(6):194
Triptonide facilitates autophagy-mediated apoptosis in esophageal squamous cell carcinoma by targeting the AMPK-mTOR-ULK1 axis.
Ju J, Xu N, Li B, Shi D, Cai J, Zheng Q, Ye L, Zhang S, Wang C
Acta biochimica et biophysica Sinica 2025 Jun 20;57(10):1611-1624
Acta biochimica et biophysica Sinica 2025 Jun 20;57(10):1611-1624
Impact of ATF6 deletion on the embryonic brain development.
Nguyen LD, Nguyen LH, Dao DX, Hattori T, Takarada-Iemata M, Ishii H, Tamatani T, Kawasaki H, Shinmyo Y, Onoue K, Yonemura S, Zhang J, Miyake M, Oyadomari S, Mori K, Hori O
iScience 2025 Jun 20;28(6):112569
iScience 2025 Jun 20;28(6):112569
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitophagy.
Li Y, Shang J, Zhang H, Lu Y, Zhao Y, Wang Y, Yan X, Zhang J
ACS chemical neuroscience 2025 Jun 18;16(12):2208-2216
ACS chemical neuroscience 2025 Jun 18;16(12):2208-2216
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Fan L, Xu F, Liu S, Wu D, Wang S, Pan X, Zhou Y, Qu L, Zhou W
European journal of histochemistry : EJH 2025 Jun 17;69(3)
European journal of histochemistry : EJH 2025 Jun 17;69(3)
Pomalidomide promotes macrophage control of Mycobacterium tuberculosis via enhancing HDAC6-mediated autophagy.
Zhang F, Dong Y, Yang Z, Guo C, Zhang X, Shang Y, Li L, Gao M, Pang Y
International immunopharmacology 2025 Jun 17;158:114831
International immunopharmacology 2025 Jun 17;158:114831
Exposure of the human placental primary cells to nanoplastics induces cytotoxic effects, an inflammatory response and endocrine disruption.
Poinsignon L, Lefrère B, Ben Azzouz A, Chissey A, Colombel J, Djelidi R, Ferecatu I, Fournier T, Beaudeux JL, Lespes G, Zerrad-Saadi A
Journal of hazardous materials 2025 Jun 15;490:137713
Journal of hazardous materials 2025 Jun 15;490:137713
CD44 Deficiency Induces Combinatory NRF2 Inhibition and Endoplasmic Reticulum Stress-Associated Dyserythropoiesis.
Yang R, Yu D, Ren J, Yin J, Li J, Liu X, Lv X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70695
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70695
Developmental programming: mechanisms of early exposure to real-life chemicals in biosolids on offspring ovarian dynamics†.
Zhou Y, Halloran KM, Bellingham M, Lea RG, Evans NP, Sinclair KD, Smith P, Padmanabhan V
Biology of reproduction 2025 Jun 15;112(6):1229-1242
Biology of reproduction 2025 Jun 15;112(6):1229-1242
Melatonin attenuates kidney injury by alleviating lysosomal damage in diabetic kidney disease.
Chen J, Zhang S, Xue X, Ma X, Chen A, Wu Y, Wang G, Zhang Q, Xue Y, Jia Y, Zheng Z
Acta biochimica et biophysica Sinica 2025 Jun 13;57(10):1589-1600
Acta biochimica et biophysica Sinica 2025 Jun 13;57(10):1589-1600
Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.
Gramatyka M
International journal of molecular sciences 2025 Jun 10;26(12)
International journal of molecular sciences 2025 Jun 10;26(12)
Molecular mechanism of rapamycin-induced autophagy activation to attenuate smoking-induced COPD.
Wang L, Jia J, Yu X, Luo M, Li J, Khan GJ, He C, Duan H, Zhai K
Biochemical and biophysical research communications 2025 Jun 1;764:151819
Biochemical and biophysical research communications 2025 Jun 1;764:151819
The compound XueShuanTong promotes podocyte mitochondrial autophagy via the AMPK/mTOR pathway to alleviate diabetic nephropathy injury.
Zhang C, Ren W, Lu X, Feng L, Li J, Zhu B
Mitochondrion 2025 Jul;83:102024
Mitochondrion 2025 Jul;83:102024
ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis.
Li X, Li W, Xie X, Fang T, Yang J, Shen Y, Wang Y, Wang H, Tao L, Zhang H
Molecular neurobiology 2025 Jul;62(7):9271-9289
Molecular neurobiology 2025 Jul;62(7):9271-9289
Activation of LAMP1-mediated lipophagy by sulforaphane inhibits cellular senescence and intervertebral disc degeneration.
Qin T, Shi M, Xie Y, Feng N, Liu C, Chen K, Chen Y, Zheng W, Zhu M, Peng S, Xiao G, Long H
Journal of orthopaedic translation 2025 Jul;53:12-25
Journal of orthopaedic translation 2025 Jul;53:12-25
YBX1 promotes 5-Fluorouracil resistance in gastric cancer via m5C-dependent ATG9A mRNA stabilization through autophagy.
Huang H, Fang L, Zhu C, Lv J, Xu P, Chen Z, Zhang Z, Wang J, Wang W, Xu Z
Oncogene 2025 Jul;44(28):2357-2371
Oncogene 2025 Jul;44(28):2357-2371
TRIM21-driven K63-linked ubiquitination of RBM38c, as a novel interactor of BECN1, contributes to DNA damage-induced autophagy.
Xia L, Xing Y, Ye X, Wu Y, Yang Y, Yin Z, Wang A, Chen J, Zhang M
Cell death and differentiation 2025 Jul;32(7):1317-1335
Cell death and differentiation 2025 Jul;32(7):1317-1335
Sevoflurane: A dual modulator of miR‑211‑5p and mitochondrial apoptosis in glioma therapy.
Wang H, Cheng G, Zhang S, Qu H, Zhao X, Yang A, Sun X, Pan H
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
Encephalomyocarditis virus non-structural protein 2C induces the degradation of NDP52 autophagy protein to promote its own survival.
Mo R, Cheng R, Dong P, Ma T, Zhang Y, Xie J, Li S, Li H, Idris A, Li X, Feng R
Veterinary microbiology 2025 Jul;306:110549
Veterinary microbiology 2025 Jul;306:110549
Visualizing bulk autophagy in vivo by tagging endogenous LC3B.
Gao X, Xiong Y, Ma H, Zhou H, Liu W, Sun Q
Autophagy 2025 Jul;21(7):1591-1607
Autophagy 2025 Jul;21(7):1591-1607
Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma.
Shi H, Yang Y, Gao J, Kumar S, Xie H, Chen Z, Lyu J, Sihto H, Koljonen V, Vega-Rubin-de-Celis S, Vukojevic V, Farnebo F, Björnhagen V, Höög A, Juhlin CC, Lee L, Wickström M, Becker JC, Johnsen JI, Larsson C, Lui WO
Autophagy 2025 Jul;21(7):1523-1543
Autophagy 2025 Jul;21(7):1523-1543
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Li XJ, Huang KX, Wang KX, Liu R, Wang DC, Liang YR, Hao EJ, Wang Y, Guo HM
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Sex-dependent effects of heat exposure on the middle ear health in mice.
Li J, Fan W, Yuan X, Wan T, Qin L, Zhang L, Hou T, Liu C, Li R
Journal of thermal biology 2025 Jul;131:104198
Journal of thermal biology 2025 Jul;131:104198
TREM2 inhibits LPS-induced pyroptosis and inflammation by promoting mitophagy via SYK in BV2 cells.
Jiang W, Fan X, Wu H, Song J, Yang C, Zhao Z
Neurotoxicology and teratology 2025 Jul-Aug;110:107500
Neurotoxicology and teratology 2025 Jul-Aug;110:107500
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Jiang R, Wang H, Zhong F, Hu Y, Liu J, Chen Y, Su W, Cao S, Deng Q, Zhou Q
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Localized brain stimulation with mild magnetic hyperthermia promotes microglia activity towards reactive and autophagic phenotypes in vivo.
Jeon BT, Naveed M, Puleo M, Kim WY, Kim MH
Scientific reports 2025 Jul 8;15(1):24425
Scientific reports 2025 Jul 8;15(1):24425
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Kang J, Jie L, Fu H, Zhang L, Lu G, Yu L, Tian D, Liao T, Yin S, Xin R, Wang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70811
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70811
Dysfunction of Autophagy in Adipose Tissue Macrophages Regulated via FoxO1 in Obesity-Related Severe Acute Pancreatitis.
Ling X, Zhang Z, Lin L, Guo X, Ding Z
International journal of molecular sciences 2025 Jul 25;26(15)
International journal of molecular sciences 2025 Jul 25;26(15)
Jianpi Huayu decoction enhances the antitumor effect of doxorubicin via piezo1-mediated autophagy in hepatocellular carcinoma.
Fang C, Liu S, Zhang S, Zheng H, Fang G, Chen C, Zhang Y, Yao R, Chen X, Luo R, Li J, Zhong C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156908
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156908
Paeonol ameliorates diabetic nephropathy by promoting TFEB-mediated lysosome biogenesis and lipophagy.
Ai S, Tao J, Wang Y, Zhou J, Liu W, Li X, Wang L, Hou J, Zhao L, Wang Z, Peng L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156901
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156901
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Jia LL, Wu CJ, Ye PW, Zhang Q, Liu H, Li TP, Hu XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy.
Li J, Zeng S, Sun Y, Zou J, Zhang E, Yan Q, Chen L, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156825
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156825
Fufang zhenzhu tiaozhi capsule alleviates hypothalamic endoplasmic reticulum stress and leptin resistance through autophagy modulation in DIO rats.
Hua T, Wu Q, Huang Z, Cai J
Journal of ethnopharmacology 2025 Jul 24;351:120056
Journal of ethnopharmacology 2025 Jul 24;351:120056
Lichong Decoction represses colorectal cancer progression via inhibiting the PINK1/Parkin pathway regulated by Rab27B.
Dai Y, Li F, Tang Y, Sun L, Liu Y, Zhan J, Zhou C, Li A
Journal of ethnopharmacology 2025 Jul 24;351:119997
Journal of ethnopharmacology 2025 Jul 24;351:119997
The RNF8/OPTN/KDM6A axis controls macrophage polarization to maintain testicular microenvironment homeostasis.
Guo Y, Xia P, Tian Y, Fu D, Hu X, Xie K, Dong W, Zhang W, Liu D, Shen R, Wang D
Cell death discovery 2025 Jul 24;11(1):339
Cell death discovery 2025 Jul 24;11(1):339
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Chen X, Liu Q, Wu J, Zhou P, Zhao M, Song J
Nature communications 2025 Jul 23;16(1):6769
Nature communications 2025 Jul 23;16(1):6769
MARCH6 suppresses Tembusu virus replication by targeting viral NS5 protein for TOLLIP-mediated selective autophagic degradation.
Zhou P, Wu W, Wei J, Yang Y, Jongkaewwattana A, Xiao Y, Jin H, Zhou H, Luo R
Journal of virology 2025 Jul 22;99(7):e0073525
Journal of virology 2025 Jul 22;99(7):e0073525
Biomimetic Nanoparticles Simultaneously Targeting Modulation of Lipid Metabolism and Phenotype of Macrophages for Programmed Atherosclerosis Management.
Dong X, Suo Y, Yu J, Yu F, Li F, Zheng J, Li G, Ma S, Hao Y, Zhang H, Liu B, Jiang Y
ACS nano 2025 Jul 22;19(28):25628-25644
ACS nano 2025 Jul 22;19(28):25628-25644
Ursolic acid affects autophagy and apoptosis of breast cancer through PLK1 via AKT/mTOR signaling pathway.
Yang K, Xie Z, Liu S, Xu R, Mao J, Feng W, Zhao X, Dai Y, Zou Y, Qian R, Qian R
Medical oncology (Northwood, London, England) 2025 Jul 21;42(8):358
Medical oncology (Northwood, London, England) 2025 Jul 21;42(8):358
A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses.
Li X, Wang X, Liu X, Shan G, Chen L
Nature communications 2025 Jul 21;16(1):6695
Nature communications 2025 Jul 21;16(1):6695
Uridine alleviates the aging of alveolar epithelial cells in idiopathic pulmonary fibrosis through the Keap1-Nrf2 signaling pathway.
Ding C, Zuo R, Liao Q, Guo Z, He J, Ye Z, Liu G
Scientific reports 2025 Jul 2;15(1):22952
Scientific reports 2025 Jul 2;15(1):22952
Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter.
Ren Y, Wang Z, Wei Z, Zhuang R, Zhang Y, Liu X, Jiang C, Liu X, Yun Y, Li Y, Hong W, Wang T
iScience 2025 Jul 18;28(7):112931
iScience 2025 Jul 18;28(7):112931
NKD1 enhances colon cancer progression by inhibiting the autophagic degradation of MYC.
Lu W, Tang J, Wang Y, Gu X, Zhang H, Liu Y, Xiao Y, Zhu Q, Deng J, Shen Y, Jiang A, Xu Y, Jin J, Hou Y, Liu Q
Cell death & disease 2025 Jul 17;16(1):532
Cell death & disease 2025 Jul 17;16(1):532
Kumatakenin alleviates depressive-like behaviors by suppressing excessive autophagy in hippocampus via ATG5.
Li L, Gu L, Hua Y, Xu H, Ling Y, Tong L, Chen M, Ma R
European journal of pharmacology 2025 Jul 15;999:177688
European journal of pharmacology 2025 Jul 15;999:177688
MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro.
Yuan C, Li C, Lu J, Liao S, Wu R, Li D, Huang M, Gong D, Wu W, Yu X, Fei S, Si W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70797
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70797
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
Ji Y, Li R, Tang G, Xiao Y, Ye R, Shi J, Geng C, Ran R, Zhu C, Wang W, Chen C, Yang Q
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy.
Cai D, Chen X, Xu H, Zhao Q, Zhou X, Wu J, Yuan S, Gao Y, Li D, Zhang R, Peng W, Li G, Nan A
Journal of experimental & clinical cancer research : CR 2025 Jul 14;44(1):203
Journal of experimental & clinical cancer research : CR 2025 Jul 14;44(1):203
DHX9-mediated epigenetic silencing of BECN1 contributes to impaired autophagy and tumor progression in breast cancer via recruitment of HDAC5.
Li Z, Liu F, Li F, Zeng G, Wen X, Ding J, Zhou J
Cell death & disease 2025 Jul 14;16(1):524
Cell death & disease 2025 Jul 14;16(1):524
Hsa_circ_0016662 acts as a prognostic biomarker and promotes the progression of hepatocellular carcinoma via autophagy regulation.
Deng G, He Y, Gan B, Liao C, Luo X, Zheng C, Mao L
Journal of translational medicine 2025 Jul 1;23(1):714
Journal of translational medicine 2025 Jul 1;23(1):714
Self-propelled smart nanomotors for enhanced mild photothermal therapy of tumors through autophagy modulation.
Mei L, Liu H, Ding Q, Xie Y, Shen X, Chen H, Wang K, Li M, He Q
Acta biomaterialia 2025 Jul 1;201:574-590
Acta biomaterialia 2025 Jul 1;201:574-590
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.
Hou D, Hu Y, Yun T, Yu D, Yang G
Brain research 2025 Jul 1;1858:149638
Brain research 2025 Jul 1;1858:149638
Viruses hijack FPN1 to disrupt iron withholding and suppress host defense.
Tong L, Wang J, Ma Y, Wang C, Fu Y, Li Q, Gao C, Song H, Qin Y, Zhao C, Zhao W
Nature communications 2025 Jul 1;16(1):5912
Nature communications 2025 Jul 1;16(1):5912
A gain-of-function mutation in ATP6V0A4 drives primary distal renal tubular alkalosis with enhanced V-ATPase activity.
Peng SQ, Wu QQ, Wang WY, Zhang YL, Zhou RN, Liao J, Wei JX, Yang Y, Shi W, Yang JL, Wang XX, Wei ZY, Sun JX, Huang L, Fan H, Cai H, Wang CK, Li XH, Li TS, Liu BC, Zhang XL, Wang B
The Journal of clinical investigation 2025 Jul 1;135(13)
The Journal of clinical investigation 2025 Jul 1;135(13)
Discovery of structurally diverse diazatricyclododecenes as lysosomotropic autophagy inhibitors.
Miura K, Umedera K, Doi T, Nakamura H
Bioorganic & medicinal chemistry 2025 Jul 1;124:118200
Bioorganic & medicinal chemistry 2025 Jul 1;124:118200
Impact of quercetin on autophagy and apoptosis induced by a high concentration of CuSO(4) in porcine ovarian granulosa cells.
Qi N, Wang B, Xing W, Li M, Liu J
Domestic animal endocrinology 2025 Jan;90:106881
Domestic animal endocrinology 2025 Jan;90:106881
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4.
He Z, Zheng D, Li F, Chen L, Wu C, Zeng Z, Yu C
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jan;78:101171
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jan;78:101171
PCSK9 promotes vascular neointimal hyperplasia through non-lipid regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Zhang Q, Miao M, Cao S, Liu D, Cao Z, Bai X, Yin Y, Jin S, Dong L, Zheng M
Biochemical and biophysical research communications 2025 Jan;742:151081
Biochemical and biophysical research communications 2025 Jan;742:151081
METTL3 methylated KIF15 promotes nasopharyngeal carcinoma progression and radiation resistance by blocking ATG7-mediated autophagy through the activation of STAT3 pathway.
Li S, Wang S, Zhang L, Wu X, Tian L, Zou J, Pi G
Translational oncology 2025 Jan;51:102161
Translational oncology 2025 Jan;51:102161
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy.
Zhang R, Lu M, Ran C, Niu L, Qi Q, Wang H
Journal of ginseng research 2025 Jan;49(1):80-91
Journal of ginseng research 2025 Jan;49(1):80-91
Dapagliflozin improves the dysfunction of human umbilical vein endothelial cells (HUVECs) by downregulating high glucose/high fat-induced autophagy through inhibiting SGLT-2.
Lin L, Zhong S, Zhou Y, Xia J, Deng S, Jiang T, Jiang A, Huang Z, Wang J
Journal of diabetes and its complications 2025 Jan;39(1):108907
Journal of diabetes and its complications 2025 Jan;39(1):108907
Mitigation of high-fat diet-induced sarcopenia by Toona sinensis fruit extracts via autophagic flux and mitochondrial quality control.
Chen YC, Chan YC, Chang YC, Liu HW, Cheng CC, Chang SJ
Food science and biotechnology 2025 Jan;34(1):245-256
Food science and biotechnology 2025 Jan;34(1):245-256
LAPTM5 Confers the Resistance to Venetoclax via Promoting the Autophagosome-Lysosome Fusion in Multiple Myeloma.
Li Y, Bai J, Liu D, Hao J, Yan R, Guo H, Huang Y, Yu H, Leng H, Zhou K, Liu M
Journal of cellular and molecular medicine 2025 Jan;29(1):e70331
Journal of cellular and molecular medicine 2025 Jan;29(1):e70331
Inhibiting UGCG prevents PRV infection by decreasing lysosome-associated autophage.
Fan W, Yao C, Ma Y, Wang H, Liu P, Zhang Z, Chu B, Yang G, Wang M
International journal of biological macromolecules 2025 Jan;285:138303
International journal of biological macromolecules 2025 Jan;285:138303
Lack of retinal degeneration in a Dram2 knockout mouse model.
Sun K, Chen J, Fan Y, Cai J, Jiang X, Liu W, Zhu X
Vision research 2025 Jan;226:108509
Vision research 2025 Jan;226:108509
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.
Sun Z, Ma Z, Cao W, Jiang C, Guo L, Liu K, Gao Y, Bai J, Pi J, Jiang P, Liu X
PLoS pathogens 2025 Jan;21(1):e1012872
PLoS pathogens 2025 Jan;21(1):e1012872
BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons.
Jin Y, Zhao L, Zhang Y, Chen T, Shi H, Sun H, Ding S, Chen S, Cao H, Zhang G, Li Q, Gao J, Xiao M, Sheng C
Autophagy 2025 Jan;21(1):223-242
Autophagy 2025 Jan;21(1):223-242
Phosphorylation of the selective autophagy receptor TAX1BP1 by TBK1 and IKBKE/IKKi promotes ATG8-family protein-dependent clearance of MAVS aggregates.
White J, Choi YB, Zhang J, Vo MT, He C, Shaikh K, Harhaj EW
Autophagy 2025 Jan;21(1):160-177
Autophagy 2025 Jan;21(1):160-177
Paeoniflorin ameliorates reperfusion injury in H9C2 cells through SIRT1-PINK1/parkin-mediated mitochondrial autophagy.
Chen X, Sun T, Qi Y, Zhu B, Li L, Yu J, Ding Z, Zhou F
Molecular immunology 2025 Jan;177:32-43
Molecular immunology 2025 Jan;177:32-43
Porphyromonas gingivalis-induced autophagy exacerbates abnormal lung homeostasis: An in vivo and in vitro study.
Zhao Q, Li W, Li W, Yang H, Wang X, Ding Z, Liu Z, Wang Z
Archives of oral biology 2025 Jan;169:106122
Archives of oral biology 2025 Jan;169:106122
Inhibition of ACSS2 triggers glycolysis inhibition and nuclear translocation to activate SIRT1/ATG5/ATG2B deacetylation axis, promoting autophagy and reducing malignancy and chemoresistance in ovarian cancer.
Yang J, Wang H, Li B, Liu J, Zhang X, Wang Y, Peng J, Gao L, Wang X, Hu S, Zhang W, Hong L
Metabolism: clinical and experimental 2025 Jan;162:156041
Metabolism: clinical and experimental 2025 Jan;162:156041
POU4F1 enhances lung cancer gemcitabine resistance by regulating METTL3-dependent TWF1 mRNA N6 adenosine methylation.
Tang J, Liu Z, Xie G, Wang C, Jiang Y
3 Biotech 2025 Jan;15(1):7
3 Biotech 2025 Jan;15(1):7
9-PAHSA ameliorates microvascular damage during cardiac ischaemia/reperfusion injury by promoting LKB1/AMPK/ULK1-mediated autophagy-dependent STING degradation.
Liu W, Hu J, Wang Y, Gan T, Ding Y, Wang X, Xu Q, Xiong J, Xiong N, Lu S, Wang Y, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156241
STIM1 promotes cervical cancer progression through autophagy activation via TFEB nuclear translocation.
Luo X, Jian M, Wu P, Wu Y, Ma Y, Feng N, Lu M, Shi D, Liu R, Ding Y, Zhang W, Fan L, He X
Cellular signalling 2025 Jan;125:111500
Cellular signalling 2025 Jan;125:111500
The BET inhibitor JQ1 suppresses tumor survival by ABCB5-mediated autophagy in uveal melanoma.
Liu W, Cui Z, Wan Q, Liu Y, Chen M, Cheng Y, Sang X, Su Y, Gu S, Li C, Liu C, Chen S, Wang Z, Wang X
Cellular signalling 2025 Jan;125:111483
Cellular signalling 2025 Jan;125:111483
Oxycodone attenuates endotoxin-induced acute lung injury by regulating mitophagy via the HO-1 pathway.
Liu C, Wang Y, Li S, Shi J, Wang P, Ma Y, Li X, Yu J
Clinics (Sao Paulo, Brazil) 2025 Jan-Dec;80:100753
Clinics (Sao Paulo, Brazil) 2025 Jan-Dec;80:100753
Rapamycin ameliorates inflammatory pain via recovery of autophagy flux mediated by mammalian target of rapamycin (mTOR) signaling pathway in the rat spinal cord.
Zhang J, Chen S, Zhang R, Zheng X, Liu C, Zhang J, Zhang L, Yang Z, Wang L
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251317284
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251317284
Exosomes From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Oxidative Stress-Induced POI by Regulating Autophagic Homeostasis Through the AMPK Pathway.
Chen W, Feng Q, Zhang C, Yang L, Qi J
Reproductive medicine and biology 2025 Jan-Dec;24(1):e12658
Reproductive medicine and biology 2025 Jan-Dec;24(1):e12658
Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway.
Huang H, Huang Q, Wang J, Wang W, Zheng Y
Scientific reports 2025 Jan 8;15(1):1287
Scientific reports 2025 Jan 8;15(1):1287
Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord.
Drosen ME, Bulbule S, Gottschalk G, Peterson D, Allen LA, Arnold LA, Roy A
Immunologic research 2025 Jan 7;73(1):27
Immunologic research 2025 Jan 7;73(1):27
Uncovering the epigenetic regulatory clues of PRRT1 in Alzheimer's disease: a strategy integrating multi-omics analysis with explainable machine learning.
Wang F, Liang Y, Wang QW
Alzheimer's research & therapy 2025 Jan 7;17(1):12
Alzheimer's research & therapy 2025 Jan 7;17(1):12
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Zhang JL, Wang XF, Li JL, Duan C, Wang JF
Veterinary research 2025 Jan 31;56(1):23
Veterinary research 2025 Jan 31;56(1):23
Hsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation.
Mu SQ, Lin JJ, Wang Y, Yang LY, Wang S, Wang ZY, Zhao AQ, Luo WJ, Dong ZQ, Cao YG, Jiang ZA, Wang SF, Cao SH, Meng L, Li Y, Yang SY, Sun SG
Communications biology 2025 Jan 30;8(1):146
Communications biology 2025 Jan 30;8(1):146
Drug pairs of Huangqi and Dnggui alleviates pyroptosis by promoting autophagy activity via AMPK/mTOR signaling pathway in middle-cerebral artery occlusion/reperfusion in rats.
Liu L, Wang R, Gao W, Hou X, Jin X, Zhao Y, Zhou X, Zhang Y
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118982
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118982
Po-Ge-Jiu-Xin decoction alleviate sepsis-induced cardiomyopathy via regulating phosphatase and tensin homolog-induced putative kinase 1 /parkin-mediated mitophagy.
Wang Z, Wang Y, Dong C, Miao K, Jiang B, Zhou D, Dong K, Wang Y, Zhang Z
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118952
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118952
Dapagliflozin and Sirtuin-1 interaction and mechanism for ameliorating atrial fibrillation in a streptozotocin-induced rodent diabetic model.
Lee WC, Lin YW, Shih JY, Chen ZC, Wu NC, Chang WT, Liu PY
Biomolecules & biomedicine 2025 Jan 30;25(3):608-622
Biomolecules & biomedicine 2025 Jan 30;25(3):608-622
Melatonin Mitigates Acidosis-Induced Neuronal Damage by Up-Regulating Autophagy via the Transcription Factor EB.
Shi Y, Mi Z, Zhao W, Hu Y, Xiang H, Gan Y, Yuan S
International journal of molecular sciences 2025 Jan 29;26(3)
International journal of molecular sciences 2025 Jan 29;26(3)
Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis.
Wei M, Jiang Q, Bian S, Chang P, Li B, Shi C, Zhu Y, Wang Y, Hou P, Li J
Journal of nanobiotechnology 2025 Jan 29;23(1):54
Journal of nanobiotechnology 2025 Jan 29;23(1):54
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Wu X, Li Y, Wang W, Xu J, Zhao B, Sun W, Ge D, Xiong L, Dou X, Zou X, Wang L, Chen M
Scientific reports 2025 Jan 28;15(1):3542
Scientific reports 2025 Jan 28;15(1):3542
Sulforaphane regulation autophagy-mediated pyroptosis in autoimmune hepatitis via AMPK/mTOR pathway.
Yang W, Zeng S, Shao R, Jin R, Huang J, Wang X, Liu E, Zhou T, Li F, Chen Y, Chen D
International immunopharmacology 2025 Jan 27;146:113826
International immunopharmacology 2025 Jan 27;146:113826
The role of HIF-1α/BNIP3/mitophagy in acrylonitrile-induced neuronal death in HT22 cells and mice: A potential neuroprotection target.
Hu J, Yang B, Tao Z, Chen J, Zhang X, Wang S, Xing G, Ngeng NA, Malik A, Appiah-Kubi K, Farina M, Skalny AV, Tinkov AA, Aschner M, Lu R
Chemico-biological interactions 2025 Jan 25;406:111327
Chemico-biological interactions 2025 Jan 25;406:111327
Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence.
Kong K, Li B, Chang Y, Zhao C, Qiao H, Jin M, Wu X, Fan W, Wang L, Qi Y, Xu Y, Zhai Z, Ma P, Li H
Journal of nanobiotechnology 2025 Jan 22;23(1):34
Journal of nanobiotechnology 2025 Jan 22;23(1):34
Blue Light Damages Retinal Ganglion Cells Via Endoplasmic Reticulum Stress and Autophagy in Chickens.
Pan D, Hu G, Li J, Wang Z, Chen Y, Cao J
Investigative ophthalmology & visual science 2025 Jan 2;66(1):3
Investigative ophthalmology & visual science 2025 Jan 2;66(1):3
Beclin 1-Mediated Autophagy Is Potentiated by an Interaction with the Neuronal Adaptor FE65.
Chan WWR, Chow J, Chau DD, Zhai Y, Lau KF
Biology 2025 Jan 18;14(1)
Biology 2025 Jan 18;14(1)
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.
Yu C, Zhang C, Zhang Q, Zhang C, Han J, Li J
iScience 2025 Jan 17;28(1):111590
iScience 2025 Jan 17;28(1):111590
ZFAND6 promotes TRAF2-dependent mitophagy to restrain cGAS-STING signaling.
Shaikh K, Bowman M, McCormick SM, Gao L, Zhang J, White J, Tawil J, Kapoor A, Arav-Boger R, Norbury CC, Harhaj EW
iScience 2025 Jan 17;28(1):111544
iScience 2025 Jan 17;28(1):111544
Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.
Jia Y, Li R, Li Y, Kachler K, Meng X, Gießl A, Qin Y, Zhang F, Liu N, Andreev D, Schett G, Bozec A
Bone research 2025 Jan 16;13(1):9
Bone research 2025 Jan 16;13(1):9
PLIN5 contributes to lipophagy of hepatic stellate cells induced by inorganic arsenic.
Li H, Xie X, Qiu T, Zhang J, Bai J, Yang G, Wang N, Yao X, Sun X
Ecotoxicology and environmental safety 2025 Jan 15;290:117547
Ecotoxicology and environmental safety 2025 Jan 15;290:117547
Deapioplatycodin D inhibits glioblastoma cell proliferation by inducing BNIP3L-mediated incomplete mitophagy.
Sun Y, Zhu G, Zhao R, Li Y, Li H, Liu Y, Jin N, Li X, Li Y, Liu T
Cancer cell international 2025 Jan 13;25(1):11
Cancer cell international 2025 Jan 13;25(1):11
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice.
Sun S, Yu T, Huh JY, Cai Y, Yoon S, Javaid HMA
Skeletal muscle 2025 Jan 13;15(1):2
Skeletal muscle 2025 Jan 13;15(1):2
Targeting on the PI3K/mTOR: a potential treatment strategy for clear cell ovarian carcinoma.
Zheng K, Jin G, Cao R, Gao Y, Xu J, Chai R, Kang Y
Cancer chemotherapy and pharmacology 2025 Jan 10;95(1):21
Cancer chemotherapy and pharmacology 2025 Jan 10;95(1):21
RICTOR-mediated activation of AKT/mTOR signaling and autophagy inhibition promote osteoarthritis.
Xu J, Wang G, Hou Y, Sun K, Zheng Z, Guo Z, Hou L, Zhang X, Ruan Z, Ye Y, Guo F
International immunopharmacology 2025 Jan 10;144:113681
International immunopharmacology 2025 Jan 10;144:113681
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis.
Xie X, Li H, Luo B, Fan X, Li Y, Zhang Y, Cui X, Yin W, Liu B, Xu H, Cheng H, Li W, Yu H, Wu F
International immunopharmacology 2025 Jan 10;144:113670
International immunopharmacology 2025 Jan 10;144:113670
CAVIN2 attenuates ventilator-induced lung injury in rats by MAPK/ERK1/2 signaling pathway.
Zhu Q, Wu K, Lv J, Yang R, Li C, Liu W, Zhang J, Lian S, Wang L, Zhang X
International immunopharmacology 2025 Jan 10;144:113669
International immunopharmacology 2025 Jan 10;144:113669
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Zhao B, Tan WL, Yu BB, Fan J, Liu C, Liu J, Liu Z
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis.
Liu C, Huang X, Kong J, Li X, Wang Y, Zhang F, Duan J
Ecotoxicology and environmental safety 2025 Jan 1;289:117441
Ecotoxicology and environmental safety 2025 Jan 1;289:117441
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy.
Zhou Y, Zhang Y, Li Y, Liu L, Zhuang M, Xiao Y
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):245-256
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):245-256
Investigation of oral toxicity of WS(2) nanosheets to mouse intestine: Pathological injury, trace element balance, lipid profile changes, and autophagy.
Zha X, Luo S, Wei L, Li F, Li Y, Cao Y
Journal of applied toxicology : JAT 2025 Feb;45(2):311-321
Journal of applied toxicology : JAT 2025 Feb;45(2):311-321
HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagy.
Jia X, Wang Y, Jiang M, Chen DD, Shang G, Liu B, Xue M, Lang Y, Zhou G, Dong Y, Zhang F, Peng X, Hu Y
The Journal of biological chemistry 2025 Feb;301(2):108126
The Journal of biological chemistry 2025 Feb;301(2):108126
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
Jiang H, Xie Y, Hu Z, Lu J, Zhang J, Li H, Zeng K, Peng W, Yang C, Huang J, Han Z, Bai X, Yu X
PLoS biology 2025 Feb;23(2):e3002961
PLoS biology 2025 Feb;23(2):e3002961
A quinolinyl analog of resveratrol improves neuronal damage after ischemic stroke by promoting Parkin-mediated mitophagy.
Meng Q, Mi Y, Xu L, Liu Y, Liang D, Wang Y, Wang Y, Liu Y, Chen G, Hou Y
Chinese journal of natural medicines 2025 Feb;23(2):214-224
Chinese journal of natural medicines 2025 Feb;23(2):214-224
Hypoxia-inducible factor-1α promotes ferroptosis by inducing ferritinophagy and promoting lactate production in yak longissimus thoracis et lumborum postmortem.
Zhu X, Yang C, Yu Q, Han L
Meat science 2025 Feb;220:109692
Meat science 2025 Feb;220:109692
Chronic alcohol consumption exacerbates ischemia-associated skeletal muscle mitochondrial dysfunction in a murine model of peripheral artery disease.
Fletcher E, Miserlis D, Papoutsi E, Steiner JL, Gordon B, Haynatzki G, Pacher P, Koutakis P
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167584
N(6)-Methyladenosine modification mediated by METTL3 promotes DNA-PKcs expression to induce anlotinib resistance in osteosarcoma.
Zhang Y, Shen G, Zhang D, Meng T, Lv Z, Chen L, Li J, Li K
Clinical and translational medicine 2025 Feb;15(2):e70228
Clinical and translational medicine 2025 Feb;15(2):e70228
The effect and mechanism of atorvastatin regulating PI3K-Akt-mTOR pathway on radiosensitivity of hepatocellular carcinoma cells.
Deng Z, Guo J, Zhu Z, Qing Q, Wan D, Lei P, Liu Q, Huang B
Toxicology research 2025 Feb;14(1):tfae202
Toxicology research 2025 Feb;14(1):tfae202
Salvianolic acid B improves diabetic skin wound repair through Pink1/Parkin-mediated mitophagy.
Zhang C, Xiang J, Wang G, Di T, Chen L, Zhao W, Wei L, Zhou S, Wu X, Zhang Y, Wang Y, Liu H
Archives of physiology and biochemistry 2025 Feb;131(1):40-51
Archives of physiology and biochemistry 2025 Feb;131(1):40-51
CDC20-Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma.
Fan Y, Dan W, Que T, Wei Y, Liu B, Wang Z, Zhang Y, Wang Y, Liu T, Zhuang Y, Li M, Guo C, Zeng J, Ma B, Li L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2412967
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2412967
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux.
Lv Y, Song B, Yang G, Wang Y, Wu Z, Si M, Yang Z, Chen H, Liu C, Li M, Zhang Y, Qiao Z, Wang L, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(5):e2409425
Autophagy is involved in the toxicity of the biocontrol agent GC16 against Tetranychus pueraricola (Acari: Tetranychidae) based on transcriptomic and proteomic analyses.
He Y, Du G, Wang G, Guan H, Zhu S, Chen B, He X, Zhu Y
BMC genomics 2025 Feb 7;26(1):119
BMC genomics 2025 Feb 7;26(1):119
Beclin1 regulates yak endometrial inflammation and TLR4/NF-κB signaling pathway through autophagy/non-autophagy function.
Ma W, Wang L, Pan Y, Wang M, Wang J, Feng M, Wang J, Zhang H, Zhang R, Jiao Z, Cui Y, Yu S
International immunopharmacology 2025 Feb 6;147:113940
International immunopharmacology 2025 Feb 6;147:113940
Therapeutic effect of dihydroartemisinin on Alzheimer's disease model mice with senile macular degeneration.
Han G, Xuewu G, Meng Z, Yuejing W, Yuchun W, Keshuang Z, Hongbo Y
European journal of medical research 2025 Feb 5;30(1):81
European journal of medical research 2025 Feb 5;30(1):81
Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling.
Ding K, Zhang Z, Han Z, Shi L, Li X, Liu Y, Li Z, Zhao C, Cui Y, Zhou L, Xu B, Zhou W, Zhao Y, Wang Z, Huang H, Xie L, Chen XW, Chen Z
Science (New York, N.Y.) 2025 Feb 28;387(6737):eadp4120
Science (New York, N.Y.) 2025 Feb 28;387(6737):eadp4120
Salidroside protects against myocardial infarction via activating MIF-mediated mitochondrial quality control.
You B, Zhang J, Yang C, Dun Y, Qi D, Long Y, Cheng J, Lin Y, Zhou N, Zeng T, Dong J, Liu S
Chinese medicine 2025 Feb 28;20(1):27
Chinese medicine 2025 Feb 28;20(1):27
Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy.
Asare O, Shim L, Lee CJ, Delgado J, Quailes N, Zavala K, Park J, Hafeez BB, Cho YY, Chauhan SC, Kim DJ
Cell death discovery 2025 Feb 28;11(1):80
Cell death discovery 2025 Feb 28;11(1):80
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Exposure to Nanoplastics During Pregnancy Induces Brown Adipose Tissue Whitening in Male Offspring.
Shen Z, Tian K, Tang J, Wang L, Zhang F, Yang L, Ge Y, Jiang M, Zhao X, Yang J, Chen G, Wang X
Toxics 2025 Feb 27;13(3)
Toxics 2025 Feb 27;13(3)
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster.
Yang W, Sun J, Guo Q, Wang W, Leng J, Wang L, Song L
Cell communication and signaling : CCS 2025 Feb 25;23(1):110
Cell communication and signaling : CCS 2025 Feb 25;23(1):110
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis.
Gu L, Wang S, Zhou L, Wang W, Bao Y, He Y, Yang T, Sun J, Jiang Q, Shan T, Du C, Wang Z, Wang H, Xie L, Gu A, Zhao Y, Ji Y, Wang Q, Wang L
Communications biology 2025 Feb 23;8(1):292
Communications biology 2025 Feb 23;8(1):292
In vitro analysis of the molecular mechanisms of ursolic acid against ovarian cancer.
Zhang R, Zhang Z, Xie L, Yu Z, Gao R, Zhang ZR, Zhang Y, Wei X, Chen Y, Jiao S, Gao Y, Guo JP
BMC complementary medicine and therapies 2025 Feb 21;25(1):65
BMC complementary medicine and therapies 2025 Feb 21;25(1):65
THSWD upregulates the LTF/AMPK/mTOR/Becn1 axis and promotes lysosomal autophagy in hepatocellular carcinoma cells by regulating gut flora and metabolic reprogramming.
Zhu Z, Zuo S, Zhu Z, Wang C, Du Y, Chen F
International immunopharmacology 2025 Feb 20;148:114091
International immunopharmacology 2025 Feb 20;148:114091
Paeoniflorin Inhibits Porcine Circovirus Type 2 Replication by Inhibiting Autophagy and Targeting AKT/mTOR Signaling.
Wu Z, Yu L, Hu Y, Bao W, Wu S
Veterinary sciences 2025 Feb 2;12(2)
Veterinary sciences 2025 Feb 2;12(2)
Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling.
Xia H, Tai XJ, Cheng W, Wu Y, He D, Wang LF, Liu H, Zhang SY, Sun YT, Liu HZ, Liu DD, Zhao HZ, Ji FY, Li XH
Scientific reports 2025 Feb 19;15(1):6081
Scientific reports 2025 Feb 19;15(1):6081
RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene.
Zhao X, Xu Y, Li S, Bai S, Zhang W, Zhang Y
Biomolecules 2025 Feb 18;15(2)
Biomolecules 2025 Feb 18;15(2)
Layered Double Hydroxide LDH-Loaded miR-141-3p Targets RAB10 Suppressing Cellular Autophagy to Reverse Paclitaxel Resistance in Breast Cancer.
Tao S, Ji Y, Li R, Xiao Y, Wu H, Ye R, Shi J, Geng C, Tang G, Ran R, Zhu C, Wang W, Chen C, Yang Q
ACS omega 2025 Feb 18;10(6):5886-5899
ACS omega 2025 Feb 18;10(6):5886-5899
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Wang F, Xiao W, Li J, Zhang Z, Zhang X, Sun J, Zhong Y, Wang X, Zhuang R, Gu X
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Chondrocyte-targeted bilirubin/rapamycin carrier-free nanoparticles alleviate oxidative stress and modulate autophagy for osteoarthritis therapy.
Huang H, Liang X, Li S, Yan Y, Li S, Qiu C, Ye Z, Zhu Y, Shen D, Lin Y, Wang L, Chen N, Yao Y, Zhao X, Wu F, Shi X, Kou L, Chen R, Yao Q
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:517-533
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:517-533
Berberine attenuates obesity-induced skeletal muscle atrophy via regulation of FUNDC1 in skeletal muscle of mice.
Wu Y, Yang Y, Du C, Peng X, Fan W, Chang B, Shan C
Scientific reports 2025 Feb 10;15(1):4918
Scientific reports 2025 Feb 10;15(1):4918
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Zhang L, Zheng G, Zhao W, He C, Huang Z
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.
Fu Y, Huang G, Cai Y, Ren M, Cheng R, Chai Y, Wang Y, An Y, Yan T, Zhu L, Liu X
Chemico-biological interactions 2025 Feb 1;407:111368
Chemico-biological interactions 2025 Feb 1;407:111368
20(R)-ginsenoside Rg3 protects against focal cerebral ischemia‒reperfusion injury by suppressing autophagy via PI3K/Akt/mTOR signaling pathway.
Tao D, Li F, Zhang X, Guo H, Yang R, Yang Y, Zhang L, Shen Z, Teng J, Chen P, He B
Neuropharmacology 2025 Feb 1;263:110226
Neuropharmacology 2025 Feb 1;263:110226
Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.
Zhang J, Fu Z, Wen F, Lyu P, Huang S, Cai X, Zhang Z, Zhang Y, Fan C, Man W, Sun X, Huang Y
Journal of neurophysiology 2025 Feb 1;133(2):490-501
Journal of neurophysiology 2025 Feb 1;133(2):490-501
Mammalian Sterile 20-Like Kinase 2 Knockdown Alleviates Neuropathic Pain in Rats by Mitochondrial Protection.
Zeng Q, Huang BX, Liu C, Liang N, Yu J, Liao SJ
Molecular neurobiology 2025 Dec;62(12):15628-15646
Molecular neurobiology 2025 Dec;62(12):15628-15646
Personalized Cancer Immunotherapy Boosted by cGAS-STING-Targeted Nanovaccines in Combination With Nutrient Modulation.
Huang W, Cao G, Tan M, Jia F, Zhang J, Su W, Yin Y, Wang H
Exploration (Beijing, China) 2025 Dec;5(6):20240183
Exploration (Beijing, China) 2025 Dec;5(6):20240183
RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression.
Liu X, Wang W, Cao W, Li Z, Huang H, Liu F, Wang Y, Zhong Z, Zhang H, Pei X, Chen H
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):2001-2015
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):2001-2015
L1CAM enhances autophagy via inhibition of p38 phosphorylation in colorectal cancer development and progression.
Hu X, Wu T, Xie Y, Zhou J, Liu C, Shi L, Xie L, Shi H
Genes & genomics 2025 Dec;47(12):1333-1342
Genes & genomics 2025 Dec;47(12):1333-1342
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Ma Z, Tu L, Yang X, Mao M, Chen G, Chen F, Liao L, Xu Y
Biochemistry and biophysics reports 2025 Dec;44:102351
Biochemistry and biophysics reports 2025 Dec;44:102351
Study on the effect of HMGB1 on immune cells isolated from SLE mice.
Qin X, Gao J, Liu X, Chen J, Song X
Biochemistry and biophysics reports 2025 Dec;44:102262
Biochemistry and biophysics reports 2025 Dec;44:102262
Biomolecule-tailored chiral nickel oxide nanozymes amplify autophagy-mediated tumor ablation via synergistic photodynamic-chemodynamic therapy.
Pang W, Shao Y, Xu H, Li T, Wu L, Liu Z, Zhang L, Chen W, Li Y, Xu D, Cheng J, Xu X
Materials today. Bio 2025 Dec;35:102303
Materials today. Bio 2025 Dec;35:102303
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Huang Y, Liu Q, Chen L, Tan X, Zeng D, Zhang Y, Qin J, Zeng F, Wei X, Zhong Q, Zhang J, Yuan D
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
Regulation of nuclear transport of the transcriptional factor REST improves axon regeneration in peripheral nerves.
Suzuki T, Naito K, Kubota D, Ueno Y, Negishi-Koga T, Yamamoto Y, Kawakita S, Imazu N, Kawamura K, Hattori N, Ishijima M
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Traditional Chinese Medicinal Leech Induces Apoptosis and Autophagy in Glioblastoma by SGK1/Caspase-3 and PI3K/AKT/mTOR Pathway.
Wu S, Zhou Y, Pei Z, Wang Y, Zhang Z
CNS neuroscience & therapeutics 2025 Dec;31(12):e70683
CNS neuroscience & therapeutics 2025 Dec;31(12):e70683
Sesamin alleviates drug-induced hepatotoxicity via autophagy enhancement and ferroptosis inhibition.
Ren J, Wang Z, Zhang Y, Pei H, Wen R, Zhang Z, Zhu S, Sun X, Yin B, Li S, Ma Y
Redox report : communications in free radical research 2025 Dec;30(1):2588863
Redox report : communications in free radical research 2025 Dec;30(1):2588863
The umbilical cord blood exosome MFG-E8 alleviates hypoxic-ischemic encephalopathy brain injury in neonatal rats by restoring autophagy flux and inhibiting ferroptosis through GSK3β/β-catenin signaling.
Zhao M, Wu Y, Huang L, Wang J, Zhang A
Regenerative therapy 2025 Dec;30:321-332
Regenerative therapy 2025 Dec;30:321-332
COX-2 targeting Ru-arene complexes from metal-ligand synergistic enhancement strategy for breast cancer therapy.
Zhang GD, Hao W, Yu ZH, Liu HK, Su Z
Journal of inorganic biochemistry 2025 Dec;273:113044
Journal of inorganic biochemistry 2025 Dec;273:113044
Cytosolic TOP3α facilitates mitochondrial DNA sensing by cGAS.
Cai D, Chen C, Meekrathok P, Zeng W, Wang Z, Peng Z, Mo Y, Xu X, Wang J, Qiu J
EMBO reports 2025 Dec;26(23):5959-5981
EMBO reports 2025 Dec;26(23):5959-5981
Overcoming ELDR-mediated cancer cell survival in vitro and in vivo via sphingomyelin-driven TRPML1 inactivation and TFEB suppression through lysosomal HSP70 targeting.
Chen H, Zhu M, Zhao Z, Jiang Y, Wang H, Liu Y, Chen Y, Li H, Xun C, Hui H
Pharmacological research 2025 Dec;222:108050
Pharmacological research 2025 Dec;222:108050
Dietary monounsaturated fatty acid facilitates lipid droplet turnover through chaperone HSP90A-mediated lysosomal degradation of PLIN2 in hepatocellular carcinoma.
Luo X, Zhao J, Chen Q, Liu D, Lu Q, Tian C, Liu H, Yu X, He J, Ruan XZ, Yang P, Chen Y
Autophagy 2025 Dec;21(12):3287-3303
Autophagy 2025 Dec;21(12):3287-3303
Excessive autophagic degradation of MYLK3 causes sunitinib-induced cardiotoxicity.
Pan Z, Zhu L, Wang X, Huangfu N, Su P, Yang F, Fu X, Pu L, Fu Q, Chen J, Cui H, Liang P, Shen J
Autophagy 2025 Dec;21(12):2730-2749
Autophagy 2025 Dec;21(12):2730-2749
Pseudorabies virus gM protein and herpesvirus homologs block selective autophagy to enhance viral replication.
Zhou Q, Shi D, Tang YD, Zhang L, Liu H, Ye G, Zhang Z, Hu B, Huang L, Weng C
Autophagy 2025 Dec;21(12):2597-2613
Autophagy 2025 Dec;21(12):2597-2613
m6A Methylation-Induced Autophagy Impairment by TFEB Regulation in SOD1-G93A ALS Cell Model.
An D, Wu Y, Han J, Fang P, Bu Y, Ji G, Deng J, Song X
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2025 Dec;198(8):221-229
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2025 Dec;198(8):221-229
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
Liao CT, Lin YC, Huang HJ, Liu WC, Kan WC, Chiu HW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Dec;193:118748
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Dec;193:118748
Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke.
Ikegami T, Sasaki T, Shimbo T, Kitayama T, Yamamoto Y, Ouchi Y, Yamazaki S, Sugiyama S, Nishiyama K, Gon Y, Okazaki S, Todo K, Matsumura S, Tamai K, Mochizuki H
Neurochemistry international 2025 Dec;191:106086
Neurochemistry international 2025 Dec;191:106086
MiR-646 inhibited cell proliferation and migration by targeting P62 in glioma.
Ye F, Zhang H, Chen Q, Gui Y, Tian G, Ye Y, Chen X, Dong H, Fan X, Chen J, Yuan R, Zhao L, Yu J
Cell adhesion & migration 2025 Dec;19(1):2515763
Cell adhesion & migration 2025 Dec;19(1):2515763
Matrix stiffness-sensitive LDHA drives autophagy of pancreatic ductal adenocarcinoma via inducing FOXO3 expression and lactylation.
Gong T, Han Q, Zhang Y, Zhu K, Chen Y, Tao Y, Xing H, Wu D, Ma Y, Zhang S
Biomaterials advances 2025 Dec;177:214401
Biomaterials advances 2025 Dec;177:214401
Laminar double hydroxide-loaded miR-654-3p targets POU2F1-mediated metabolic reprogramming against colorectal cancer.
Shi J, Zhu C, Xu S, Ran R, Ye R, Xiao Y, Ji Y, Geng C, Tang G, Li R, Ding Y, Wang W, Yang Q, Chen C
Bioorganic chemistry 2025 Dec;167:109234
Bioorganic chemistry 2025 Dec;167:109234
Artemisia argyi ethyl acetate fraction suppresses ovarian cancer progression via JUN/MAPK10 signaling: An integrated multi-omics investigation.
Liu Y, Yu T, Liu M, Mo Y, Zheng Y, Xu J, Song Z, Gui C, Liu D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157533
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157533
Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.
Zhang J, Li X, Sun L, Chen B, Zhang R, Duan J
The Journal of nutritional biochemistry 2025 Dec;146:110080
The Journal of nutritional biochemistry 2025 Dec;146:110080
WDR4-mediate tRNA m7G modification to promote mitophagy and browning of white adipose tissue for ameliorating obesity in male mice.
Lin B, Wang C, Yang Y, Liu Z, Mu P, Xu W, Li Y
Adipocyte 2025 Dec;14(1):2588888
Adipocyte 2025 Dec;14(1):2588888
PARP inhibitors accumulate B7-H3 on fibroblasts via blocking autophagic flux to potentiate immune evasion in ovarian cancer.
Fang T, Xia Y, Li Y, Xu S, Li H, Wang S, Huang P, Qian Y, Jin P, Jin N, Xu C, Wang Z, Xiong X, Wang M, Zhou D, Wang Y, Li X, Xu T, Zhang Q, Liu D, Fang Y, Zhao GN, Gao Q
Oncoimmunology 2025 Dec;14(1):2516294
Oncoimmunology 2025 Dec;14(1):2516294
Blocking T-type calcium channels disrupts spermatogenesis in vivo and adversely affects spermatocytes in vitro by impairing mitochondrial function and autophagic flux.
Zhao X, Wang L, Huang S, Liu L, Wang X, Pu L, Chen H, Nie J
Reproductive toxicology (Elmsford, N.Y.) 2025 Dec;138:109048
Reproductive toxicology (Elmsford, N.Y.) 2025 Dec;138:109048
Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells.
Huang J, Fang K, Lu W, Wu R, Chen Y, Li L, Hu Z, Cai Z, Jiang Y, Fan X, Deng J, Liu G, Luo Z, Cui L, Li S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e07803
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e07803
Liposomal honokiol enhance the anti-tumor effect of bevacizumab in glioblastoma by inhibiting autophagy.
Xun P, Zong J, Li S, Li W
Future science OA 2025 Dec;11(1):2546232
Future science OA 2025 Dec;11(1):2546232
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
Yang Y, Li M, Wang J, Zhang H, Chang R, Zhao B, Aernouts B, Huang Q, Xu C
Journal of dairy science 2025 Dec;108(12):13919-13937
Journal of dairy science 2025 Dec;108(12):13919-13937
Research note: duck Tembusu virus non-structural protein 3 induced autophagy through endoplasmic reticulum stress.
Zhang S, Fu J, Zhu L, Lu Y, Zhang Z, Yu L, Qiu J, Wang G, Li N
Poultry science 2025 Dec;104(12):105990
Poultry science 2025 Dec;104(12):105990
KDM6B induces demethylation of H3K27me3 in MFN1 to modulate aberrant mitophagy in sepsis-induced acute lung injury.
Deng H, Zhu S, Song X, Guo Y, Ding X
Scientific reports 2025 Dec 8;15(1):43339
Scientific reports 2025 Dec 8;15(1):43339
OPRK1 drives SLC9A3R1 progression to neuroendocrine prostate cancer.
Liang L, Shen Z, Zhang Y, Cheng Y, Yao B, Feng N, Zhao R
Cell death & disease 2025 Dec 7;17(1):68
Cell death & disease 2025 Dec 7;17(1):68
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Deng Y, Jiang X, Che Z, Shang Y, Hu M, Wang W, Yu W, Yang B, Liu X
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Molecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy.
Liu J, Meng S, Wang Z, Fan Y, Pei S, Cui J, Liu J, Song Y, Huang X, Li X, Cui Y, Xie K
European journal of medical research 2025 Dec 5;31(1):113
European journal of medical research 2025 Dec 5;31(1):113
Lack of intestinal Mucin-1 impairs intestinal epithelial barrier and promotes metabolic dysfunction-associated steatotic liver disease in male mice.
Li Z, Gu R, Liu D, Zhang Y, Qin Y, Li X, Qiao Y, Li Z, Guo J, Wang J, Meng H, Peng L
Nature communications 2025 Dec 5;17(1):321
Nature communications 2025 Dec 5;17(1):321
Identification of ferroptosis-related genes as diagnostic biomarkers and therapeutic targets in sorafenib-resistant HCC via machine learning and experimental validation.
Zhang J, Geng W, Sun H, Chen J, Fan Y, Tan K
International immunopharmacology 2025 Dec 3;166:115557
International immunopharmacology 2025 Dec 3;166:115557
Regulation of autophagy by oncogene DJ1 via the JNK signaling pathway in human ovarian cancer cells.
Zhao XM, Wang K, Wang Z, Xie D, Liu H, Li P, Wang WM
Journal of ovarian research 2025 Dec 27;19(1):30
Journal of ovarian research 2025 Dec 27;19(1):30
Synthesis and Biological Evaluation of a Caffeic Acid Phenethyl Ester Derivatives as Anti-Hepatocellular Carcinoma Agents via Inhibition of Mitochondrial Respiration and Disruption of Cellular Metabolism.
Dong H, Gao Y, Jiang D, Feng C, Gu X, Cai X, Liu Y, Zhang G, Wen J, Diao W, Zhou Y, Li R, Xu D, Xie W, Wu L
Cancers 2025 Dec 27;18(1)
Cancers 2025 Dec 27;18(1)
Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.
Mecca M, Sichetti M, Spina E, Giuseffi M, Giglio E, Picerno S, Valvano L, Statuto T, Santarsiere A, Funicello M, Armentano MF, Chiummiento L, Lupattelli P, Romano A, Giordano A, Cortellino S
Cancer cell international 2025 Dec 23;26(1):44
Cancer cell international 2025 Dec 23;26(1):44
Propofol addiction drives neuronal senescence and cognitive decline via autophagy-mediated ADAR1/SIRT1 disruption.
Wang X, Lin S, Zou Z, Zhu D, Zhou J, Zhang X, Lv J, Zhou W, Liu Y, Si Z
Communications biology 2025 Dec 22;8(1):1832
Communications biology 2025 Dec 22;8(1):1832
Does hypoxemia aggravate sepsis-associated acute kidney injury? Integrated clinical and experimental evidence.
Mao H, Xu J, Zhu Y, Kong X, Li J, Zhu X, Xu Y
Intensive care medicine experimental 2025 Dec 21;13(1):134
Intensive care medicine experimental 2025 Dec 21;13(1):134
Role of Esketamine in Attenuating Neuroinflammation and Improving Postoperative Cognitive Function via Autophagy Activation Through PARP1 Targeting.
Zhao C, Liu J, Zhao S, Liu P, Li Z, Li Y, Dong R, Wang XL
Physiological research 2025 Dec 2;74(5):871-884
Physiological research 2025 Dec 2;74(5):871-884
Effects of psychosocial stress on myocardial injury by modulating endoplasmic reticulum stress-induced autophagy and inflammation.
Gao X, Huang G, Hao R, Wang L, Ma A, Zhang Z, Zhao T
iScience 2025 Dec 19;28(12):114022
iScience 2025 Dec 19;28(12):114022
Apoptotic extracellular vesicles from peripancreatic adipose-derived mesenchymal stem cells ameliorate severe acute pancreatitis through the transcription factor EB-mediated autophagy-lysosomal pathway: an experimental study.
Wang A, An Y, Wang X, Gou W, Xu F, Li Y, Wang C, Tu Z, Hou W, Cui Y
International journal of surgery (London, England) 2025 Dec 17;112(4):9262-81
International journal of surgery (London, England) 2025 Dec 17;112(4):9262-81
Platelet-hitchhiking triiodothyronine nanoparticles for enhanced therapy of cerebral ischemia-reperfusion injury.
Syeda MZ, Su G, Li Y, Bai H, Liu Y, Mu Q, Tang L, Huang W
Journal of colloid and interface science 2025 Dec 15;700(Pt 1):138290
Journal of colloid and interface science 2025 Dec 15;700(Pt 1):138290
Antigen B from Echinococcus granulosus regulates autophagy-mediated macrophage polarization to alleviate immune thrombocytopenia.
Song HC, Li DL, Wang JJ, Jiao HJ, Li MW, Zhao L, Yang XH, Yan M
Parasites & vectors 2025 Dec 15;19(1):38
Parasites & vectors 2025 Dec 15;19(1):38
Liraglutide alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic rats by enhancing mitophagy mediated by the AMPK-Parkin signaling pathway.
Zhu YX, Zhang W, Qu HL, Zhang Y, Zhou RQ, Li P, Wang F, Zhang Y, Liu HH, Li S, Dong Q, Dou KF, Guo YL, Li JJ, Xu RX
World journal of diabetes 2025 Dec 15;16(12):112423
World journal of diabetes 2025 Dec 15;16(12):112423
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
Wu Y, Chen C, Xie J, Chang X, Zhang Y, Zheng Y, Yuan Y, Hu W, Xie X
NPJ science of food 2025 Dec 11;10(1):9
NPJ science of food 2025 Dec 11;10(1):9
Fibrotic collagen-targeted delivery system blocks pancreatic intercellular crosstalk to alleviate pancreatic fibrosis.
Wang H, Qi L, Fang YF, Liu Y, Ye Z, Chen BT, Wang Y, Jiang HL, Li L
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114278
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114278
A study on the mechanism by which BCAT1 influences the formation of intracranial aneurysms by regulating autophagy through endoplasmic reticulum stress.
Liu S, Guan H, Wang F
International immunopharmacology 2025 Dec 10;167:115667
International immunopharmacology 2025 Dec 10;167:115667
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
Yao Z, Tan X, Cui H, Liang H, Zhong A, Man Y, Yi T, Zhang Z, Guo X, Tan S, Zhu X
International immunopharmacology 2025 Dec 10;167:115664
International immunopharmacology 2025 Dec 10;167:115664
PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13.
Lou J, Zhu H, Yang Z, Jiang P, Liu G, Wang X
mBio 2025 Dec 10;16(12):e0239625
mBio 2025 Dec 10;16(12):e0239625
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Liu J, Zhang C, Ma R, Yin C, Ren J, Yang S, Zhao Y, Tang Y, Wei J, Li X
Free radical biology & medicine 2025 Dec 1;240:514-531
Free radical biology & medicine 2025 Dec 1;240:514-531
Discovery of a novel mitophagy inducer attenuating postoperative cognitive dysfunction through structure-based virtual screening and biological validation.
Zhang L, Wu Y, Li J, Li C, Liu S, Qi S
Free radical biology & medicine 2025 Dec 1;240:46-58
Free radical biology & medicine 2025 Dec 1;240:46-58
Calcineurin/NFAT1/Smad2 signaling regulates microglial autophagy that contributes to neuroinflammation and cognitive deficit in mice with sepsis-associated encephalopathy.
Ding R, Hu N, Zhang X, Jiang F, Feng Y, Li Z, Tang S, Li W, Shi H, Si Y
Free radical biology & medicine 2025 Dec 1;240:15-28
Free radical biology & medicine 2025 Dec 1;240:15-28
mTORC1-dependent suppression of autophagic activity in somatic cell nuclear transfer mouse embryos.
Tatebe T, Pham DQ, Ogura A, Inoue K
Reproduction (Cambridge, England) 2025 Dec 1;170(6)
Reproduction (Cambridge, England) 2025 Dec 1;170(6)
Tooth Loss Leads to Cognitive Impairment and Mitochondrial Disturbance in Wistar Rats.
Meng S, Lu Y, Hu J, Luo B, Sun X, Wang X, Jiang Q
International dental journal 2025 Aug;75(4):100818
International dental journal 2025 Aug;75(4):100818
Salidroside sensitizes Triple-negative breast cancer to ferroptosis by SCD1-mediated lipogenesis and NCOA4-mediated ferritinophagy.
Huang G, Cai Y, Ren M, Zhang X, Fu Y, Cheng R, Wang Y, Miao M, Zhu L, Yan T
Journal of advanced research 2025 Aug;74:589-607
Journal of advanced research 2025 Aug;74:589-607
Effect of spermidine on cuproptosis in follicular granulosa cells.
Li S, Qi Y, Qi Y, Wang Z, Xu S, Xiao T, Zhu Y, Zheng W, Wang X, Jiang D, Kang B
British poultry science 2025 Aug;66(4):539-546
British poultry science 2025 Aug;66(4):539-546
Demethylzeylasteral inhibits proliferation and metastasis of osteosarcoma cells by modulating the PI3K/AKT/Autophagy pathways.
Yuan X, Li J, Yu B, Cai F, Chen B, Liu J, Peng Y, Zeng D, Liao Q, Liu L
Journal of bone oncology 2025 Aug;53:100699
Journal of bone oncology 2025 Aug;53:100699
Berberine Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU Through Smoothing Endoplasmic Reticulum Stress-Mediated Autophagic Flux.
Xu J, Hu M, Li Y, Gong H, Zhang X, He Z, Xiao C, Yang C, Zeng J
Cell biology international 2025 Aug;49(8):1042-1055
Cell biology international 2025 Aug;49(8):1042-1055
A biomimetic multimodal nanoplatform combining neutrophil-coated two-dimensional metalloporphyrinic framework nanosheet and exendin-4 to treat obesity-related osteoporosis.
Yang Q, Liu J, Liu Y, Liu S, Wei X, Yang Y, Zhang W, Zhang S, Zhang M, Liu B, Wang X, Zhu D
Materials today. Bio 2025 Aug;33:102009
Materials today. Bio 2025 Aug;33:102009
Reduced iron bioavailability drives acute high‑altitude lung injury through HIF1α activation and mitophagy.
Geng Y, Hu Y, Wang H, Zhang F, Ge RL
Molecular medicine reports 2025 Aug;32(2)
Molecular medicine reports 2025 Aug;32(2)
Zika virus capsid protein impairs neural differentiation.
Wang Y, Ma ZH, Hassaan NA, Hao G, Wang PH, Yao M, Wu C, Chen M, Xing L
International journal of biological macromolecules 2025 Aug;319(Pt 2):145479
International journal of biological macromolecules 2025 Aug;319(Pt 2):145479
Zn(2+)-driven metformin conjugated with siRNA attenuates osteoarthritis progression by inhibiting NF-κB signaling and activating autophagy.
He H, Huang C, Huang H, Lan N, Liu S, Luo Y, Zheng L, Liu G, Qin Z, Zhao J
Biomaterials 2025 Aug;319:123210
Biomaterials 2025 Aug;319:123210
Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis.
Zhu C, Huang K, Li T, Li Y, Jin Y, Li R, Zhu Z, Yang S, Xia L, Fang B
Biomaterials 2025 Aug;319:123179
Biomaterials 2025 Aug;319:123179
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
Chen B, Liu B, Chen J, Li W, Ma N, Liu J, Fan R, Hu Q, Song H, Xu Y, Jiang T, Song J
Autophagy 2025 Aug;21(8):1680-1699
Autophagy 2025 Aug;21(8):1680-1699
Cilostazol attenuates vascular inflammation via the regulation of TICAM1/IRF3 signaling pathway.
Chiu HW, Shih CC, Huang HJ, Huang TH, Sung LC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Aug;189:118275
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Aug;189:118275
Biliverdin alleviates cerebral ischemia-reperfusion injury by regulating the P4hb/MAPK/mTOR pathway to inhibit autophagy.
Jiang H, Bai W, Yang Y, Zhou G, Li J, Li X, Wan X, Shao J
Cellular signalling 2025 Aug;132:111815
Cellular signalling 2025 Aug;132:111815
β-Mangostin Attenuates TET2-Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration.
Kong X, Gu H, Zhang Y, Meng Q, Li Q, Song K, Li Y, Liu K, Liu Z, Hu R, Zhai H, Li T, Ling Z, Wei Z, Wei F, Cheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e05077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e05077
NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA.
Zhan YJ, Deng CM, Tang L, Li SJ, Xu TY, Wei X, Zhang XY, Zheng CC, Deng L, Shao C, Ouyang ZM, Lam AK, Zhang R, Liu J, Shi XY, Pan ZY, Dai W, He ML, Law S, Li X, Chen XB, Zhou C, Li B, Xu WW
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e02931
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e02931
Whey protein hydrolysate alleviated acetaminophen-induced hepatocyte pyroptosis by activating mitophagy.
Zhang S, Guo J, Liu M, Chen Y, Shen X, Wang J, Deng X, Guan S
Journal of dairy science 2025 Aug;108(8):7896-7911
Journal of dairy science 2025 Aug;108(8):7896-7911
c-FLIP Protects Cardiac Microcirculation in Sepsis-Induced Myocardial Dysfunction Via FUNDC1-Mediated Regulation of Mitochondrial Autophagy.
Gao L, Shi Q, Sun B, Zhang X, Zheng P, Zhou L, Tian G, Li H
JACC. Basic to translational science 2025 Aug;10(8):101257
JACC. Basic to translational science 2025 Aug;10(8):101257
1,3-Dichloro-2-propanol Causes Lipid Droplet Accumulation by Inhibiting Autophagy via REV-ERBα in Hepatocytes.
Chen Y, Peng H, Wang Z, Zhang D, Lang L, Lu J, Guan S
Journal of agricultural and food chemistry 2025 Aug 6;73(31):19789-19801
Journal of agricultural and food chemistry 2025 Aug 6;73(31):19789-19801
Camellia japonica Flower Extract and the Active Constituent Hyperoside Repair DNA Damage Through FUNDC1-Mediated Mitophagy Pathway for Skin Anti-Aging.
Gao H, Shi J, Li G, Lai Z, Liu Y, Yuan C, Mei W
Antioxidants (Basel, Switzerland) 2025 Aug 6;14(8)
Antioxidants (Basel, Switzerland) 2025 Aug 6;14(8)
Genetic depletion of early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Toriola MA, Timlin E, Bulbule S, Reyes A, Adedeji OM, Gottschalk CG, Barua A, Arnold LA, Roy A
Research square 2025 Aug 6;
Research square 2025 Aug 6;
Hyperoxia-induced oxidative stress enhances TMEM106B to impair ULK1-mediated autophagy via TLR3/JNK signaling.
Xu M, Jiang X, Peng C, Jiang J, Qin T, Qin H, Zeng C, Cheng Y, Yuan X, Wu S, Li X, Xie X, Yang S, Mo S
Journal of leukocyte biology 2025 Aug 5;117(8)
Journal of leukocyte biology 2025 Aug 5;117(8)
MCOLN1-Mediated Endoplasmic Reticulum Stress Induces Autophagy to Facilitate Lung Cancer Growth, Migration, and Invasion.
Jiang H, Zhang X, Cai J, Li L, Huang P, Zhang S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70942
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70942
Identifying Key Genes of Proanthocyanidin Intervention in Fluoride-Induced Liver Injury: Integrated Molecular Docking and Experimental Validation.
Wu Z, Xiao M, Gong Z, Wang B, Zhao W, Guo Y, Yang L
Genes 2025 Aug 31;16(9)
Genes 2025 Aug 31;16(9)
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
Li J, Chen Y, Wang J, Liu L, Qadir J, Xie D, Wan X, Luo Y, Xian J, Ye T
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
Exosomes derived from umbilical cord mesenchymal stem cells alleviate jaw bone marrow mesenchymal stem cells senescence and restore osteogenic differentiation potential.
Li H, Xu N, Li S, Wang X, Li A, Wang H, Wu S, Zhou S, Cai C, Zhang T
Stem cell research & therapy 2025 Aug 29;16(1):475
Stem cell research & therapy 2025 Aug 29;16(1):475
Melatonin-induced ferroptosis in pancreatic cancer cells by stimulating endoplasmic reticulum stress and inhibiting alanine-serine-cysteine transporter 2-driven glutamine metabolism.
Zhao Q, Zhang H, Wu HM, Yang QY, Zhao H, Kang L, Lv XY
World journal of gastroenterology 2025 Aug 28;31(32):108654
World journal of gastroenterology 2025 Aug 28;31(32):108654
PP2A attenuates α-amanitin-induced liver injury by promoting autophagy and inhibiting apoptosis in mouse models.
Xu H, Sun J, Zhao Y, Zhou Y, Wang K, Liu X, Yang J, Wu P, Wang S, Kastelic JP, Qu W, Zhang L, Gu X
Chemico-biological interactions 2025 Aug 25;417:111558
Chemico-biological interactions 2025 Aug 25;417:111558
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
Cong J, Liu L, Shi R, He M, An Y, Feng X, Yin X, Li Y, Cong B, Shi W
International journal of molecular sciences 2025 Aug 25;26(17)
International journal of molecular sciences 2025 Aug 25;26(17)
ETAS(®), a Standardized Extract of Asparagus officinalis Stem, Alleviates Sarcopenia via Regulating Protein Turnover and Mitochondrial Quality.
Chang SJ, Chen YC, Chang YC, Cheng CC, Chan YC
Pharmaceuticals (Basel, Switzerland) 2025 Aug 22;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 22;18(9)
NDUFB9 ameliorates CUMS-induced depression-like behavior by promoting mitophagy.
Sun Y, Li L, Yang X, Yin S, Xiao Z
Translational psychiatry 2025 Aug 18;15(1):292
Translational psychiatry 2025 Aug 18;15(1):292
Succinate accumulation induces pyroptosis and mitochondrial damage via the inhibition of ATP5F1D in HUVECs.
Huang H, Cui J, Tang D, Xiang X, Mao J, He Z, Hu H, He Z, He L, Tang H
Acta biochimica et biophysica Sinica 2025 Aug 15;57(12):2011-21
Acta biochimica et biophysica Sinica 2025 Aug 15;57(12):2011-21
Cardamonin inhibits the growth and stemness of osteosarcoma stem cells by inducing autophagy and inhibiting the Wnt/β-catenin signaling pathway.
Zhang L, Jin Y, Ding Q, Li Y, Yang L, Li M, Lv Z, Wang K, Yang M, Zhang H, Li X
Scientific reports 2025 Aug 12;15(1):29484
Scientific reports 2025 Aug 12;15(1):29484
Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.
Lu H, Fu W, Xia Y, Yan Y, Shu C, Chen Y, Xu C, Zheng P, Shen X, Cui R, Zou P, Ni D
Cell death discovery 2025 Aug 1;11(1):360
Cell death discovery 2025 Aug 1;11(1):360
Cordycepin Ameliorates Kainic Acid-Induced HT22 Cell Neurotoxicity by Activating GPR120-Mediated Mitophagy.
San Y, Wang M
Developmental neurobiology 2025 Apr;85(2):e22961
Developmental neurobiology 2025 Apr;85(2):e22961
TRIM36 Inhibits the Development of AOM/DSS-Induced Colitis-Associated Colorectal Cancer by Promoting the Ubiquitination and Degradation of GRB7.
Wu J, Yang Z, Chen X, Hou S, Li N, Chang Y, Yin J, Xu J
Molecular carcinogenesis 2025 Apr;64(4):668-679
Molecular carcinogenesis 2025 Apr;64(4):668-679
Neuroprotective Effects of AER-271 in a tMCAO Mouse Model: Modulation of Autophagy, Apoptosis, and Inflammation.
Mo S, Yang C, Zheng X, Lv H, Mao S, Liu N, Yang Q, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Li X, Shang J
Inflammation 2025 Apr;48(2):713-729
Inflammation 2025 Apr;48(2):713-729
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Yang Q, Yang C, Lv H, Zheng X, Mao S, Liu N, Mo S, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Shang J
Inflammation 2025 Apr;48(2):541-556
Inflammation 2025 Apr;48(2):541-556
The Mechanistic Study of Mitochondrial Autophagy and Ferroptosis in the Progression of Decreased Ovarian Reserve.
Ma Q, Wu L, Wu J, Ni B, Wang J, Song S
Reproductive sciences (Thousand Oaks, Calif.) 2025 Apr;32(4):1202-1212
Reproductive sciences (Thousand Oaks, Calif.) 2025 Apr;32(4):1202-1212
VDAC1 Inhibition Protects Against Noise-Induced Hearing Loss via the PINK1/Parkin Pathway.
Jin Y, Dong W, Jiang Y, Dong L, Li Z, Yu D
CNS neuroscience & therapeutics 2025 Apr;31(4):e70410
CNS neuroscience & therapeutics 2025 Apr;31(4):e70410
Mycoplasma ovipnuemoniae impairs the immune response of sheep and suppresses neutrophil function by inhibiting S100A9.
Yan C, Dong T, Shan Y, Zhao B, Yang H, Cai Y, Li S, Liu Q, Chu Y, Hao H, Cheng Z, Liu M, Zhang Y
Veterinary microbiology 2025 Apr;303:110446
Veterinary microbiology 2025 Apr;303:110446
Dietary cinnamon promotes longevity and extends healthspan via mTORC1 and autophagy signaling.
Guo Y, Zhang Q, Zhang B, Pan T, Ronan EA, Huffman A, He Y, Inoki K, Liu J, Xu XZS
Aging cell 2025 Apr;24(4):e14448
Aging cell 2025 Apr;24(4):e14448
MitoQ alleviates H(2)O(2)-induced mitochondrial dysfunction in keratinocytes through the Nrf2/PINK1 pathway.
Zhao Y, Xiong R, Jin S, Li Y, Dong T, Wang W, Song X, Guan C
Biochemical pharmacology 2025 Apr;234:116811
Biochemical pharmacology 2025 Apr;234:116811
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Dai F, Cao Y, Zhu C, Li Y, Ma X, Wang S, Liu H, Xie X, Gao L, Wang Y, Wang C
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation.
Zhou P, Zhang Q, Yang Y, Chen D, Jongkaewwattana A, Jin H, Zhou H, Luo R
Autophagy 2025 Apr;21(4):754-770
Autophagy 2025 Apr;21(4):754-770
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Shi J, Zhao G, Wang S, Wei Y, Wu J, Huang G, Chen J, Xia J
Biotechnology journal 2025 Apr;20(4):e202400611
Biotechnology journal 2025 Apr;20(4):e202400611
RGFP966 inhibits palmitic acid induced VSMCs phenotypic transition by targeting ATGL.
Zhang S, Nie F, Zeng Y, Yang Z, Song W, Yan X, Tang Z, Fu Y, Guo R
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Apr;1870(3):159597
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Apr;1870(3):159597
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Liu Y, Yao C, Sheng B, Zhi S, Chen X, Ding P, Zhang J, Tao Z, Li W, Zhuang Z, Mao J, Peng Z, Yan H, Jin W
Translational stroke research 2025 Apr;16(2):448-466
Translational stroke research 2025 Apr;16(2):448-466
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Tang CT, Wu Y, Tao Q, Zeng CY, Chen YX
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Tetrandrine alleviates macrophage activation syndrome after CAR-T cell therapy.
Wang Y, Ding L, Wang Y, Li H, Wu M, Li S, Xu Q, Chen Y, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156483
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156483
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Min L, Huo F, Zhu Z, Din L, Zhang L, Xu Y, Xing X, Zhang P, Wang Q
Cellular signalling 2025 Apr;128:111649
Cellular signalling 2025 Apr;128:111649
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Li X, Jin S, Wang D, Wu Y, Tang X, Liu Y, Yao T, Han S, Sun L, Wang Y, Hou SX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
3-D Sustained-Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells.
Luo L, Zhang S, Gong J, Zhang J, Xie P, Yin J, Zhang M, Zhang C, Chen H, Liu Y, Ni B, Li C, Tian Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2410151
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2410151
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Fu Y, Zhu D, Chen X, Qu L, Guo M, Zhang S, Xu G, Chen Z, Li M, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
LncRNA NEAT1-206 regulates autophagy of human umbilical cord mesenchymal stem cells through the WNT5A/Ca(2+) signaling pathway under senescence stress.
Wang W, Wang Y, Duan C, Tian W, Gao L
Non-coding RNA research 2025 Apr;11:234-248
Non-coding RNA research 2025 Apr;11:234-248
Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy.
Ren J, Wu P, Liu M, Zhang X, Guo Z, Liu Y, Zhao R, Wang G, Duan S, Li H
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341598
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341598
ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway.
Su S, Wu L, Huang C, He C, Wang L, Li W, Liu W, Liu L
Discover oncology 2025 Apr 9;16(1):499
Discover oncology 2025 Apr 9;16(1):499
Mechanism of Mitophagy to Protect Yak Kidney from Hypoxia-Induced Fibrosis Damage by Regulating Ferroptosis Pathway.
Bai X, Lu H, Ma R, Yu S, Yang S, He J, Cui Y
Biomolecules 2025 Apr 9;15(4)
Biomolecules 2025 Apr 9;15(4)
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Li M, Wang Y, Li X, Xu J, Yan L, Tang S, Liu C, Shi M, Liu R, Zhao Y, Zhang Y, Yang L, Zhang Y, Wang G, Li Z, Guo Y, Feng Y, Liu P
Cell death & disease 2025 Apr 6;16(1):257
Cell death & disease 2025 Apr 6;16(1):257
Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis.
Li Y, Sun W, Jin X, Li H, Liu X, Bian J, Zhu X
Cell death discovery 2025 Apr 5;11(1):145
Cell death discovery 2025 Apr 5;11(1):145
Retromer promotes the lysosomal turnover of mtDNA.
Kakanj P, Bonse M, Kshirsagar A, Gökmen A, Gaedke F, Sen A, Mollá B, Vogelsang E, Schauss A, Wodarz A, Pla-Martín D
Science advances 2025 Apr 4;11(14):eadr6415
Science advances 2025 Apr 4;11(14):eadr6415
Tricin Delays Aging and Enhances Muscle Function via Activating AMPK-Mediated Autophagy in Diverse Model Organisms.
Zhu YF, Zhou XY, Lan C, Wen YP, Fu HJ, Li ZC, Li YP, Li SY, Huang FH, Wang L, Yu L, Qin DL, Wu AG, Wu JM, Zhou XG
Journal of agricultural and food chemistry 2025 Apr 30;73(17):10246-10264
Journal of agricultural and food chemistry 2025 Apr 30;73(17):10246-10264
Antiepileptic Effects of Acorus tatarinowii Schott in a Rat Model of Epilepsy: Regulation of Metabolic Axes and Gut Microbiota.
Chen L, Li J, Zhang W, Wang J
Biology 2025 Apr 29;14(5)
Biology 2025 Apr 29;14(5)
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease.
Tu WC, He YK, Wang DW, Ming SX, Zhao Y
Cellular and molecular life sciences : CMLS 2025 Apr 28;82(1):186
Cellular and molecular life sciences : CMLS 2025 Apr 28;82(1):186
Neferine Ameliorates Slow-Transmitting Constipation by Inducing PINK1/Parkin-Mediated Mitophagy in Protective Enteric Glial Cells.
Chen T, Jiang X, Ma B, Zhan Y, Wen Y, Mao L, Pang J, Tang X
Journal of microbiology and biotechnology 2025 Apr 27;35:e2412022
Journal of microbiology and biotechnology 2025 Apr 27;35:e2412022
Salvianolic Acid A Alleviates Sciatic Nerve Injury in Rats Via Inhibiting NLRP3 Inflammasome Through the Activation of Schwann Cells Autophagy.
Fu M, Zhang F, Song Y, Wang J
Neurochemical research 2025 Apr 25;50(3):152
Neurochemical research 2025 Apr 25;50(3):152
Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced nonalcoholic steatohepatitis.
Ma L, Sun H, Xiang N, Xu Q
Scientific reports 2025 Apr 25;15(1):14516
Scientific reports 2025 Apr 25;15(1):14516
Formononetin ameliorates depression-like behaviors through rebalancing microglia M1/M2 polarization and inhibiting NLRP3 inflammasome: involvement of activating PPARα-mediated autophagy.
Peng S, Su P, Liu L, Li Z, Liu Y, Tian L, Bai M, Xu E, Li Y
Molecular medicine (Cambridge, Mass.) 2025 Apr 24;31(1):153
Molecular medicine (Cambridge, Mass.) 2025 Apr 24;31(1):153
Apigenin-Mediated ESCRT-III Activation and Mitophagy Alleviate LPS-Induced Necroptosis in Renal Cells.
Guo J, Hu JP, Liu M, Chen Y, Zhang S, Guan S
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9906-9919
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9906-9919
Tricetin, a Dietary Flavonoid, Alleviates Neuroinflammation and Promotes Autophagy in Alzheimer's Disease by Regulating the PI3K/Akt/mTOR Signaling Pathway.
Wu X, Su D, Xu J, Ge G, Zhang Y, Wu B, Hu K, Ren J, Yang H
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9677-9689
Journal of agricultural and food chemistry 2025 Apr 23;73(16):9677-9689
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Zhou W, Wang J, Ding L, Cai R, Cheng J, Liang P, Zhu Y, Zhang Z
Scientific reports 2025 Apr 21;15(1):13805
Scientific reports 2025 Apr 21;15(1):13805
Hydrogen sulfide improves poststroke depression-induced inflammation in microglial cells by enhancing endoplasmic reticulum autophagy and inhibiting the cGAS-STING pathway.
Luo B, Xie Y, Kuang W, Wang Y, Chen G, Zhang Y, Yuan M
Neuroreport 2025 Apr 2;36(6):314-326
Neuroreport 2025 Apr 2;36(6):314-326
PERK/Sestrin2 Signaling Pathway Mediated Autophagy Regulates Human Cardiomyocytes Apoptosis Induced by Traffic-Related PM(2.5) and Diverse Constituents.
Tian J, Niu Z, Yang H, Wang C, Guan L, Zhao L, Shi D, Zhang Z
International journal of molecular sciences 2025 Apr 17;26(8)
International journal of molecular sciences 2025 Apr 17;26(8)
Aging and autophagic phenotypic changes in bone marrow mesenchymal stem cells in glucocorticoid-induced osteonecrosis.
Cao R, Li H, Liu G, Yan P, Zhang J, Chen Y, Duan X, Zhao Y, Lei Y, Liu C, Guan H, Xing F, Li Y, Wang K, Kong N, Tian R, Yang P
International immunopharmacology 2025 Apr 16;152:114389
International immunopharmacology 2025 Apr 16;152:114389
Engineered Extracellular Vesicles Derived from Juvenile Mice Enhance Mitochondrial Function in the Aging Bone Microenvironment and Achieve Rejuvenation.
Zheng J, Ren Y, Ke J, Zhu G, Wang Z, Shi X, Wang Y
ACS nano 2025 Apr 15;19(14):13952-13967
ACS nano 2025 Apr 15;19(14):13952-13967
Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein.
Xiao ZW, Zeng YC, Ji LT, Yuan JT, Li L
World journal of gastrointestinal oncology 2025 Apr 15;17(4):103843
World journal of gastrointestinal oncology 2025 Apr 15;17(4):103843
Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.
Fu H, Wang Y, Huang B, Liang Z, Li Y, Cao Z, Wu J, Zhao Y
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:892-909
Comprehensive profiling of lipid metabolic reprogramming expands precision medicine for HCC.
Liu Q, Zhang X, Qi J, Tian X, Dovjak E, Zhang J, Du H, Zhang N, Zhao J, Zhang Y, Wang L, Wei Y, Liu C, Qian R, Xiang L, Li W, Xiu P, Ma C, Yu Y, Jiang S
Hepatology (Baltimore, Md.) 2025 Apr 1;81(4):1164-1180
Hepatology (Baltimore, Md.) 2025 Apr 1;81(4):1164-1180
The role of TFEB-mediated autophagy-lysosome dysfunction in manganese neurotoxicity.
Lu J, Su P, Zhao F, Yu K, Yang X, Lv H, Wang D, Zhang J
Current research in toxicology 2024;7:100193
Current research in toxicology 2024;7:100193
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis.
Zhu P, Wu Z, Yang Z, Tang T, Liao Y, Zhao W, Huang Y, Chen T, Li J, Nong C, Wu Z, Hu G, Liu Y, Chen Y
Research (Washington, D.C.) 2024;7:0344
Research (Washington, D.C.) 2024;7:0344
The role and mechanism of macrophage autophagy in the experimental model of chronic obstructive pulmonary disease.
Zhang L, Cheng T, Liu C, He S, Lu J
Tobacco induced diseases 2024;22
Tobacco induced diseases 2024;22
Evidence for the potential role of m6A modification in regulating autophagy in models of amyotrophic lateral sclerosis.
An D, Han J, Fang P, Bu Y, Ji G, Liu M, Deng J, Song X
CytoJournal 2024;21:33
CytoJournal 2024;21:33
The role and underlying mechanism of dental pulp stem cell-derived exosomal miR-31 in the treatment of osteoarthritis by targeting mTOR to enhance chondrocyte autophagy levels.
Zhao G, Lyu J, Huang X, Huang G, Chen F, Wei Y, Wang S, Xia J, Chen J, Shi J
Archives of medical science : AMS 2024;20(5):1680-1694
Archives of medical science : AMS 2024;20(5):1680-1694
ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.
Tang D, Wang H, Jiang Y, Chen M, Zhang G, Wu S, Wang Y
PloS one 2024;19(12):e0316109
PloS one 2024;19(12):e0316109
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy.
Sun X, Wang H, Liu Y, Yang Y, Wang Y, Liu Y, Ai S, Shan Z, Luo P
Journal of inflammation research 2024;17:9857-9873
Journal of inflammation research 2024;17:9857-9873
Diltiazem Hydrochloride Protects Against Myocardial Ischemia/Reperfusion Injury in a BNIP3L/NIX-Mediated Mitophagy Manner.
Zhou X, Lu Q, Wang Q, Chu W, Huang J, Yu J, Nong Y, Lu W
Journal of inflammation research 2024;17:8905-8919
Journal of inflammation research 2024;17:8905-8919
Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.
Zhu J, Wang Z, Liu C, Shi M, Guo Z, Li Y, Yu R, Wei J
Journal of inflammation research 2024;17:8147-8164
Journal of inflammation research 2024;17:8147-8164
Tanshinone IIA Promoted Autophagy and Inhibited Inflammation to Alleviate Podocyte Injury in Diabetic Nephropathy.
Li Y, Wu T, Li H, Liu M, Xu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:2709-2724
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:2709-2724
Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
Liu W, Li Y, An Y, Zhao R, Wei C, Ren X, He H
Journal of inflammation research 2024;17:2271-2284
Journal of inflammation research 2024;17:2271-2284
Novel Insights from Comprehensive Bioinformatics Analysis Utilizing Large-Scale Human Transcriptomes and Experimental Validation: The Role of Autophagy in Periodontitis.
Liu F, Zhu Z, Zou H, Huang Z, Xiao S, Li Z
Journal of inflammation research 2024;17:11861-11880
Journal of inflammation research 2024;17:11861-11880
MCU promotes the migration of glioma cells by activating p38 through TFEB-mediated autophagy.
Chen J, Lu R, Peng Y, Lai Y, Cai Z, Zheng D, Xie A, Huang K, Liang C, Zhang H
Journal of Cancer 2024;15(5):1257-1270
Journal of Cancer 2024;15(5):1257-1270
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells.
Gao P, Chen A, Tian H, Wang F, Wang N, Ge K, Lian C, Wang F, Zhang Q
Journal of Cancer 2024;15(13):4313-4327
Journal of Cancer 2024;15(13):4313-4327
Ailanthone blocks mitophagy to promote mtDNA leakage through BAX-BAK1 pores and suppress hepatocellular carcinoma cell proliferation.
Qin Y, Gao Y, Wu D, Liu QQ, Su C, Liu G, Yang L, Zhao MG, Yao JY
Frontiers in pharmacology 2024;15:1509482
Frontiers in pharmacology 2024;15:1509482
Salidroside enhances 5-fluorouracil sensitivity against hepatocellular carcinoma via YIPF5-induced mitophagy.
Sun S, Hu H, Li F, Huan S, Chen L, Chen J, Sun P, Dong X
Frontiers in pharmacology 2024;15:1503490
Frontiers in pharmacology 2024;15:1503490
Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.
Xu AL, Shen Z, Wang SH, Luan HY, Xu Y, Kang ZC, Liao ZQ, Liu J, Duan XL, Bian WH, Sun H, Xie X
Frontiers in pharmacology 2024;15:1496380
Frontiers in pharmacology 2024;15:1496380
CRISPR/Cas9-mediated knockout of STAT1 in porcine-derived cell lines to elucidate the role of STAT1 in autophagy following classical swine fever virus infection.
Zhang L, Liang D, Min K, Liang J, Tian Y, Liu C, Luo TR, Li X
Frontiers in immunology 2024;15:1468258
Frontiers in immunology 2024;15:1468258
Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.
Wang H, Sun N, Sun P, Zhang H, Yin W, Zheng X, Fan K, Sun Y, Li H
Frontiers in microbiology 2024;15:1455049
Frontiers in microbiology 2024;15:1455049
Adipose mesenchymal stem cell-derived exosomes promote skin wound healing in diabetic mice by regulating epidermal autophagy.
Ren H, Su P, Zhao F, Zhang Q, Huang X, He C, Wu Q, Wang Z, Ma J, Wang Z
Burns & trauma 2024;12:tkae001
Burns & trauma 2024;12:tkae001
Sesamin alleviates lipid accumulation induced by elaidic acid in L02 cells through TFEB regulated autophagy.
Liang X, Zhang T, Cheng X, Yuan H, Yang N, Yi Y, Li X, Zhang F, Sun J, Li Z, Wang X
Frontiers in nutrition 2024;11:1511682
Frontiers in nutrition 2024;11:1511682
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice.
Cilenti L, Di Gregorio J, Mahar R, Liu F, Ambivero CT, Periasamy M, Merritt ME, Zervos AS
Frontiers in molecular biosciences 2024;11:1397565
Frontiers in molecular biosciences 2024;11:1397565
Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
Wang W, Gong Z, Wang Y, Zhao Y, Lu Y, Sun R, Zhang H, Shang J, Zhang J
Journal of Alzheimer's disease : JAD 2024;100(4):1299-1314
Journal of Alzheimer's disease : JAD 2024;100(4):1299-1314
Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies.
Lu T, Chen X, Zhang Q, Shang K, Yang X, Xiang W
Neurochemical research 2024 Sep;49(9):2379-2392
Neurochemical research 2024 Sep;49(9):2379-2392
ent-8(14),15-Pimaradiene-2β,19-diol, a diterpene from Aleuritopteris albofusca, inhibits growth and induces protective autophagy in hepatocellular carcinoma cells.
Zhang Y, Liu Z, Wang F, Liu J, Zhang Y, Cao J, Huang G, Ma L
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6867-6878
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6867-6878
Urolithin A exerts anti-tumor effects on gastric cancer via activating autophagy-Hippo axis and modulating the gut microbiota.
Qiao Y, Xia Q, Cao X, Xu J, Qiao Z, Wu L, Chen Z, Yang L, Lu X
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6633-6645
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6633-6645
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
Zhou X, Wang M, Sun M, Yao N
Molecular medicine reports 2024 Sep;30(3)
Molecular medicine reports 2024 Sep;30(3)
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy.
Jiang Y, Liu B, Fu L, Li F
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
International journal of biological macromolecules 2024 Sep;276(Pt 2):134011
IGF2 promotes the differentiation of chicken embryonic myoblast by regulating mitochondrial remodeling.
Zhao C, Hu B, Zeng X, Zhang Z, Luo W, Li H, Zhang X
Journal of cellular physiology 2024 Sep;239(9):e31351
Journal of cellular physiology 2024 Sep;239(9):e31351
The Role of BNIP3 and Blocked Autophagy Flux in Arsenic-Induced Oxidative Stress-Induced Liver Injury in Rats.
Zhi H, Bi D, Zheng D, Lu Q, Wang H, Wang Y, Lv Y, Lou D, Hu Y
Biological trace element research 2024 Sep;202(9):4054-4064
Biological trace element research 2024 Sep;202(9):4054-4064
Mechanisms of programmed cell death associated to severe dengue in human renal lesions.
Pagliari C, Quaresma JAS, Dos-Santos WLC, Duarte MIS, Carvalho LV, Penny R, Kanashiro-Galo L, Vasconcelos PFC, Sotto MN
Microbial pathogenesis 2024 Sep;194:106794
Microbial pathogenesis 2024 Sep;194:106794
JAK2 inhibitor protects the septic heart through enhancing mitophagy in cardiomyocytes.
Han D, Su T, Wang M, Zhang R, Xu H, Chu R, Zhu Z, Shen Y, Wang N, He S, Wang Y, Han Y, Wang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117279
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117279
Enhanced glioma cell death with ZnO nanorod flowers and temozolomide combination therapy through autophagy and mitophagy pathways.
Li Y, Ma Y, Li J, Lu Y, Liu H, Gao M, Cao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117149
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117149
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Pan Z, Yu X, Wang W, Shen K, Chen J, Zhang Y, Huang R
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Journal of neurochemistry 2024 Sep;168(9):2640-2653
The role of DNA damage response in human embryonic stem cells exposed to atmospheric oxygen tension: Implications for embryo development and differentiation.
Zhou Y, Ye F, Zhang L, Kang Q, Luo Y, Jiang N, Lou L, Mao Y, Wang L, Jin F
Reproductive toxicology (Elmsford, N.Y.) 2024 Sep;128:108648
Reproductive toxicology (Elmsford, N.Y.) 2024 Sep;128:108648
Lidamycin induces mitophagy in pancreatic cancer cells by regulating the expression of Mfn2.
Wu B, Qi B, Duan L, Chen J
Scientific reports 2024 Sep 5;14(1):20713
Scientific reports 2024 Sep 5;14(1):20713
Effects of the lncRNA NBR2 on the proliferation and autophagy of breast cancer cells under starvation conditions.
Yang J, Gao L, Wang Z, Xu Y, Jin X, Jin Q, Yu L
Scientific reports 2024 Sep 30;14(1):22624
Scientific reports 2024 Sep 30;14(1):22624
Platelets promote primary hepatocellular carcinoma metastasis through TGF-β1-mediated cancer cell autophagy.
Lu M, Gong X, Zhang YM, Guo YW, Zhu Y, Zeng XB, Gao JH, Liu LM, Shu D, Ma R, Liang HF, Zhang RY, Xu Y, Zhang BX, Lu YJ, Ming ZY
Cancer letters 2024 Sep 28;600:217161
Cancer letters 2024 Sep 28;600:217161
CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC.
Zhao S, Sun J, Chang Q, Pang S, Zhang N, Fan Y, Liu J
Cancer cell international 2024 Sep 28;24(1):327
Cancer cell international 2024 Sep 28;24(1):327
Autophagy defects at weaning impair complement-dependent synaptic pruning and induce behavior deficits.
Su X, Wang G, Liu S, Li J, Shao M, Yang Y, Song M, Han Y, Li W, Lv L
Journal of neuroinflammation 2024 Sep 27;21(1):239
Journal of neuroinflammation 2024 Sep 27;21(1):239
Lipid droplets sequester palmitic acid to disrupt endothelial ciliation and exacerbate atherosclerosis in male mice.
Tan Y, Huang Z, Jin Y, Wang J, Fan H, Liu Y, Zhang L, Wu Y, Liu P, Li T, Ran J, Tian H, Lam SM, Liu M, Zhou J, Yang Y
Nature communications 2024 Sep 27;15(1):8273
Nature communications 2024 Sep 27;15(1):8273
A Lysosome-Targeting hNEU1 Inhibitor Treats Myocardial Infarction: A Potential Therapeutic Breakthrough.
Zhou W, Yang W, Jiang P, Gou S
Journal of medicinal chemistry 2024 Sep 26;67(18):16899-16911
Journal of medicinal chemistry 2024 Sep 26;67(18):16899-16911
Construction of a Multifunctional Upconversion Nanoplatform Based on Autophagy Inhibition and Photodynamic Therapy Combined with Chemotherapy for Antitumor Therapy.
Ning F, Wei D, Yu H, Song T, Li Z, Ma H, Sun Y
Molecular pharmaceutics 2024 Sep 2;21(9):4297-4311
Molecular pharmaceutics 2024 Sep 2;21(9):4297-4311
Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells.
Chen D, Wu L, Liu X, Wang Q, Gui S, Bao L, Wang Z, He X, Zhao Y, Zhou J, Xie Y
Scientific reports 2024 Sep 17;14(1):21648
Scientific reports 2024 Sep 17;14(1):21648
Follicular fluid HD-sevs-mir-128-3p is a key molecule in regulating bovine granulosa cells autophagy.
Ying W, Yunqi Z, Deji L, Jian K, Fusheng Q
Theriogenology 2024 Sep 15;226:263-276
Theriogenology 2024 Sep 15;226:263-276
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Shi J, Wang Y, Liang T, Wang X, Xie J, Huang R, Xu X, Wei X
Chinese medicine 2024 Sep 12;19(1):125
Chinese medicine 2024 Sep 12;19(1):125
HBx promotes tumorigenicity through RRM2-mediated autophagy in hepatocellular carcinoma.
Li Y, Wang F, Geng Z, He T, Song Y, Wu J, Wang B
Cell & bioscience 2024 Sep 10;14(1):116
Cell & bioscience 2024 Sep 10;14(1):116
DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment.
Hwang RD, Lu Y, Tang Q, Periz G, Park G, Li X, Xiang Q, Liu Y, Zhang T, Wang J
eLife 2024 Sep 10;12
eLife 2024 Sep 10;12
Autophagy aggravates multi-walled carbon nanotube-induced ferroptosis by suppressing PGC-1 dependent-mitochondrial biogenesis in lung epithelial cells.
Zhu L, Zhu D, Ran J, Li M, Lai Z, Zhou Y, Luo L, Liu X, Mao K, Tian K
Chemico-biological interactions 2024 Sep 1;400:111158
Chemico-biological interactions 2024 Sep 1;400:111158
Lubricin-Inspired Nanozymes Reconstruct Cartilage Lubrication System with an "In-Out" Strategy.
Du C, Chen Z, Liu S, Liu J, Zhan J, Zou J, Liao J, Huang W, Lei Y
Small methods 2024 Oct;8(10):e2400757
Small methods 2024 Oct;8(10):e2400757
Placental growth factor alleviates hyperglycemia-induced trophoblast pyroptosis by regulating mitophagy.
Tao J, Rao Y, Wang J, Tan S, Zhao J, Cao Z, He L, Meng J, Wu P, Wang Z
The journal of obstetrics and gynaecology research 2024 Oct;50(10):1813-1829
The journal of obstetrics and gynaecology research 2024 Oct;50(10):1813-1829
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
Sun X, Ye G, Li J, Yuan L, Bai G, Xu YJ, Zhang J
Oncogene 2024 Oct;43(44):3215-3226
Oncogene 2024 Oct;43(44):3215-3226
Circadian gene CLOCK accelerates atherosclerosis by promoting endothelial autophagy.
Wang C, Yang X, Guo Z, Zhu G, Fan L
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1230-1245
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1230-1245
Regulation of autophagy by ST3GAL2-mediated α2-3 sialylated glycosphingolipids in hepatic encephalopathy.
Li X, Xiao Y, Zhu Y, Li P, Zhou J, Yang J, Chen Z, Du H, Yu H, Guo Y, Bian H, Li Z
International journal of biological macromolecules 2024 Oct;278(Pt 4):135196
International journal of biological macromolecules 2024 Oct;278(Pt 4):135196
Mfn2(R364W), Mfn2(G176S), and Mfn2(H165R) mutations drive Charcot-Marie-Tooth type 2A disease by inducing apoptosis and mitochondrial oxidative phosphorylation damage.
Zhang Y, Ma L, Wang Z, Gao C, Yang L, Li M, Tang X, Yuan H, Pang D, Ouyang H
International journal of biological macromolecules 2024 Oct;278(Pt 1):134673
International journal of biological macromolecules 2024 Oct;278(Pt 1):134673
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise.
Park SJ, Son SM, Barbosa AD, Wrobel L, Stamatakou E, Squitieri F, Balmus G, Rubinsztein DC
Nature cell biology 2024 Oct;26(10):1691-1699
Nature cell biology 2024 Oct;26(10):1691-1699
Sestrin2 plays a protective role in age-related hearing loss by inhibiting NLRP3-inflammasome activity.
Zheng L, Li M, Li Y, Wu L, Naveena K, Zheng M, Yang Z, Pan Y, Zhang Y, Chen S, Qiao Y, Xu Y, Chen L, Shi X
Mechanisms of ageing and development 2024 Oct;221:111964
Mechanisms of ageing and development 2024 Oct;221:111964
Bunyavirus SFTSV NSs utilizes autophagy to escape the antiviral innate immune response.
Li ZM, Duan SH, Yu TM, Li B, Zhang WK, Zhou CM, Yu XJ
Autophagy 2024 Oct;20(10):2133-2145
Autophagy 2024 Oct;20(10):2133-2145
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Zeng H, Xu J, Wu R, Wang X, Jiang Y, Wang Q, Guo J, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Targeting SMYD2 promotes ferroptosis and impacts the progression of pancreatic cancer through the c-Myc/NCOA4 axis-mediated ferritinophagy.
Tan J, Liao S, Yuan B, Liu X, Yu W, Zhan H, Jiang Y, Liu Y
Biochimica et biophysica acta. General subjects 2024 Oct;1868(10):130683
Biochimica et biophysica acta. General subjects 2024 Oct;1868(10):130683
Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS, ER stress, and blocked autophagy.
Ji Y, Li C, Wan S, Dong Z, Liu C, Guo L, Shi S, Ci M, Xu M, Li Q, Hu H, Cui H, Liu Y
Journal of pharmaceutical analysis 2024 Oct;14(10):101036
Journal of pharmaceutical analysis 2024 Oct;14(10):101036
Neuroprotective Effect of Melatonin in a Neonatal Hypoxia-Ischemia Rat Model Is Regulated by the AMPK/mTOR Pathway.
Nacarkucuk E, Bernis ME, Bremer AS, Grzelak K, Zweyer M, Maes E, Burkard H, Sabir H
Journal of the American Heart Association 2024 Oct;13(19):e036054
Journal of the American Heart Association 2024 Oct;13(19):e036054
Functional Relationships between L1CAM, LC3, ATG12, and Aβ.
Loers G, Bork U, Schachner M
International journal of molecular sciences 2024 Oct 9;25(19)
International journal of molecular sciences 2024 Oct 9;25(19)
Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice.
Zhu H, Wang H, Wang D, Liu S, Sun X, Qu Z, Zhang A, Ye C, Li R, Wu B, Liu M, Gao J
Cell death & disease 2024 Oct 6;15(10):730
Cell death & disease 2024 Oct 6;15(10):730
Targeting oncogenic MAGEA6 sensitizes triple negative breast cancer to doxorubicin through its autophagy and ferroptosis by stabling AMPKα1.
Zhu H, Jiang CW, Zhang WL, Yang ZY, Sun G
Cell death discovery 2024 Oct 6;10(1):430
Cell death discovery 2024 Oct 6;10(1):430
Ganoderic acid A mitigates dopaminergic neuron ferroptosis via inhibiting NCOA4-mediated ferritinophagy in Parkinson's disease mice.
Li QM, Wu SZ, Zha XQ, Zang DD, Zhang FY, Luo JP
Journal of ethnopharmacology 2024 Oct 5;332:118363
Journal of ethnopharmacology 2024 Oct 5;332:118363
Antitumor activity and transcriptome sequencing (RNA-seq) analyses of hepatocellular carcinoma cells in response to exposure triterpene-nucleoside conjugates.
Wang Q, Ma F, Wang J, Xu H, Li K, Cheng YY, Chen X, Qu S, Wei T, Hao X, Kong M, Xie C, Wang W, Wang Y, Jeong LS
European journal of medicinal chemistry 2024 Oct 5;276:116635
European journal of medicinal chemistry 2024 Oct 5;276:116635
MiR-155-5p regulates autophagy and apoptosis of glioma cells through RICTOR.
Guo Z, Tian JJ, Wang Y, Jiang L, Chen Y, Dai HJ, Wang L, Zhang Y
Translational cancer research 2024 Oct 31;13(10):5509-5521
Translational cancer research 2024 Oct 31;13(10):5509-5521
The RNA N6-methyladenosine demethylase FTO regulates ATG5 to inhibit malignant progression of uveal melanoma.
Yang Y, Zhong Y, Chi C, Lin X, Zhu X, Deng X, Liang J, Cheng Y
Journal of proteomics 2024 Oct 30;309:105282
Journal of proteomics 2024 Oct 30;309:105282
HSP90 Enhances Mitophagy to Improve the Resistance of Car-Diomyocytes to Heat Stress in Wenchang Chickens.
Shi J, Ji Z, Yao X, Yao Y, Li C, Liang Q, Zhang X
International journal of molecular sciences 2024 Oct 30;25(21)
International journal of molecular sciences 2024 Oct 30;25(21)
Myocardial ischemia-reperfusion injury upregulates nucleostemin expression via HIF-1α and c-Jun pathways and alleviates apoptosis by promoting autophagy.
Han X, Jiang Z, Hou Y, Zhou X, Hu B
Cell death discovery 2024 Oct 30;10(1):461
Cell death discovery 2024 Oct 30;10(1):461
Inhibition of endoplasmic reticulum stress and excessive autophagy by Jiedu Tongluo Tiaogan Formula via a CaMKKβ/AMPK pathway contributes to protect pancreatic β-cells.
Zhang Q, Jin W, Wang H, Tang C, Zhao X, Wang Y, Sun L, Piao C
Journal of ethnopharmacology 2024 Oct 28;333:118440
Journal of ethnopharmacology 2024 Oct 28;333:118440
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Huang Y, Huang Y, Cai Z, Ferrari MW, Li C, Zhang T, Lyu G, Wang Z
Communications biology 2024 Oct 22;7(1):1371
Communications biology 2024 Oct 22;7(1):1371
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation.
Wang G, Zhao R, Guo Z, Cui H, Wang D, Ren J, Zhu S, Zhang K, Tang B, Zhang J, Li P, Duan S, Li H
Human cell 2024 Oct 22;38(1):4
Human cell 2024 Oct 22;38(1):4
Luteolin Protects against Vascular Calcification by Modulating SIRT1/CXCR4 Signaling Pathway and Promoting Autophagy.
Yu X, Xu L, Su C, Wang C, Wang Z, Wang Y, Lu X, Sun H
The AAPS journal 2024 Oct 22;26(6):111
The AAPS journal 2024 Oct 22;26(6):111
PRDM1 promotes nucleus pulposus cell pyroptosis leading to intervertebral disc degeneration via activating CASP1 transcription.
Yu C, Li J, Kuang W, Ni S, Cao Y, Duan Y
Cell biology and toxicology 2024 Oct 21;40(1):89
Cell biology and toxicology 2024 Oct 21;40(1):89
A TBK1-independent primordial function of STING in lysosomal biogenesis.
Lv B, Dion WA, Yang H, Xun J, Kim DH, Zhu B, Tan JX
Molecular cell 2024 Oct 17;84(20):3979-3996.e9
Molecular cell 2024 Oct 17;84(20):3979-3996.e9
The Integrated Stress Response Suppresses PINK1-dependent Mitophagy by Preserving Mitochondrial Import Efficiency.
Yang M, Mo Z, Walsh K, Liu W, Guo X
bioRxiv : the preprint server for biology 2024 Oct 17;
bioRxiv : the preprint server for biology 2024 Oct 17;
RABIF promotes hepatocellular carcinoma progression through regulation of mitophagy and glycolysis.
Feng N, Zhang R, Wen X, Wang W, Zhang N, Zheng J, Zhang L, Liu N
Communications biology 2024 Oct 16;7(1):1333
Communications biology 2024 Oct 16;7(1):1333
METTL3 mediates m6A modification of lncRNA CRNDE to promote ATG10 expression and improve brain ischemia/reperfusion injury through YTHDC1.
Yu Z, Xia Y, Li J, Jiang J, Li Y, Li Y, Wang L
Biology direct 2024 Oct 16;19(1):92
Biology direct 2024 Oct 16;19(1):92
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53.
Wang S, Cheng T, Chen X, Zeng C, Qin W, Xu Y
Clinical science (London, England : 1979) 2024 Oct 16;138(20):1287-1304
Clinical science (London, England : 1979) 2024 Oct 16;138(20):1287-1304
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1.
Wang S, Li X, Wang T, Sun Z, Feng E, Jin Y
Communications biology 2024 Oct 15;7(1):1330
Communications biology 2024 Oct 15;7(1):1330
Black phosphorus nanosheets induce autophagy dysfunction by a size- and surface modification-related impairment of lysosomes in macrophages.
Deng S, Zhao Q, Liu D, Xiong Z, Zhang S, Zhang X, Wu F, Xing B
Ecotoxicology and environmental safety 2024 Oct 15;285:117073
Ecotoxicology and environmental safety 2024 Oct 15;285:117073
Silica nanoparticles cause ovarian dysfunction and fertility decrease in mice via oxidative stress-activated autophagy and apoptosis.
Liu W, Liu H, Zhang S, Hao H, Meng F, Ma W, Guo Z, Jiang S, Shang X
Ecotoxicology and environmental safety 2024 Oct 15;285:117049
Ecotoxicology and environmental safety 2024 Oct 15;285:117049
Nur77 ameliorates cyclophosphamide-induced ovarian insufficiency in mice by inhibiting oxidative damage and cell senescence.
Yao Y, Wang B, Yu K, Song J, Wang L, Yang X, Zhang X, Li Y, Ma X
Journal of ovarian research 2024 Oct 15;17(1):203
Journal of ovarian research 2024 Oct 15;17(1):203
Tumor-associated macrophages/C-X-C motif chemokine ligand 1 promotes breast cancer autophagy-mediated chemoresistance via IGF1R/STAT3/HMGB1 signaling.
Yang B, Li G, Wang S, Zheng Y, Zhang J, Pan B, Wang N, Wang Z
Cell death & disease 2024 Oct 11;15(10):743
Cell death & disease 2024 Oct 11;15(10):743
Ursodeoxycholic Acid Platinum(IV) Conjugates as Antiproliferative and Antimetastatic Agents: Remodel the Tumor Microenvironment through Suppressing JAK2/STAT3 Signaling.
Chen Y, Zhang M, Liu Z, Zhang N, Wang Q
Journal of medicinal chemistry 2024 Oct 10;67(19):17551-17567
Journal of medicinal chemistry 2024 Oct 10;67(19):17551-17567
Continuous Theta Burst Stimulation Inhibits Oxidative Stress-Induced Inflammation and Autophagy in Hippocampal Neurons by Activating Glutathione Synthesis Pathway, Improving Cognitive Impairment in Sleep-Deprived Mice.
Zhang Y, Zhang C, Dai Q, Ma R
Neuromolecular medicine 2024 Oct 10;26(1):40
Neuromolecular medicine 2024 Oct 10;26(1):40
GL-V9 Promotes Autophagy-Mediated YAP1 Degradation and Activates Mitochondrial Apoptosis in PDAC Cells.
Liu H, Lin Z, Guo Y, Zhou Y, Li W
Pharmaceuticals (Basel, Switzerland) 2024 Oct 10;17(10)
Pharmaceuticals (Basel, Switzerland) 2024 Oct 10;17(10)
Leptin promotes tendon stem/progenitor cell senescence through the AKT-mTOR signaling pathway.
Lei C, Li Y, Chen J, Nie D, Song X, Lei C, Zhou Y, Wang W, Sun J
Experimental cell research 2024 Oct 1;442(2):114274
Experimental cell research 2024 Oct 1;442(2):114274
Hesperetin alleviates aflatoxin B1 induced liver toxicity in mice: Modulating lipid peroxidation and ferritin autophagy.
Song C, Wang Z, Cao J, Dong Y, Chen Y
Ecotoxicology and environmental safety 2024 Oct 1;284:116854
Ecotoxicology and environmental safety 2024 Oct 1;284:116854
Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway.
Lan X, Wang Q, Liu Y, You Q, Wei W, Zhu C, Hai D, Cai Z, Yu J, Zhang J, Liu N
Redox biology 2024 Nov;77:103406
Redox biology 2024 Nov;77:103406
STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway.
Li D, Xiong Y, Li M, Long L, Zhang Y, Yan H, Xiang H
Archives of biochemistry and biophysics 2024 Nov;761:110149
Archives of biochemistry and biophysics 2024 Nov;761:110149
An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies.
Wang J, Wen Y, Zhang Y, Wang Z, Jiang Y, Dai C, Wu L, Leng D, He S, Bo X
Journal of advanced research 2024 Nov;65:329-343
Journal of advanced research 2024 Nov;65:329-343
Ferritinophagy is involved in hexavalent chromium-induced ferroptosis in Sertoli cells.
Zhuge R, Zhang L, Xue Q, Wang R, Xu J, Wang C, Meng C, Lu R, Yin F, Guo L
Toxicology and applied pharmacology 2024 Nov;492:117139
Toxicology and applied pharmacology 2024 Nov;492:117139
Propyl acetate protects intestinal barrier during parenteral nutrition in mice and Caco-2 cells.
Wang J, Du J, Gou X, Huang Y, He J, Lu X, Xie M
JPEN. Journal of parenteral and enteral nutrition 2024 Nov;48(8):917-926
JPEN. Journal of parenteral and enteral nutrition 2024 Nov;48(8):917-926
Influences of TiO(2) nanoparticle and fipronil co-exposure on metabolite profiles in mouse intestines.
Wang C, Zhou Z, He Y, Li J, Cao Y
Journal of applied toxicology : JAT 2024 Nov;44(11):1793-1803
Journal of applied toxicology : JAT 2024 Nov;44(11):1793-1803
High levels of mitochondrial dynamics, autophagy, and apoptosis contribute to stable testicular status in hibernating Daurian ground squirrels.
Wang Z, Wang MD, Wang XC, Chen L, Li LF, Jiang LN, Xu JH, Kai Dang
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2024 Nov;297:111705
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2024 Nov;297:111705
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Lu L, Chen J, Jiang H, Li N, Li X, Liu Y, Zong C
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Ciclopirox platinum(IV) conjugates suppress tumors by promoting mitophagy and provoking immune responses.
Li S, Feng S, Chen Y, Sun B, Zhang N, Zhao Y, Han J, Liu Z, He YQ, Wang Q
Journal of inorganic biochemistry 2024 Nov;260:112696
Journal of inorganic biochemistry 2024 Nov;260:112696
Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8(+) T cells.
Zhang H, Liu J, Yuan W, Zhang Q, Luo X, Li Y, Peng Y, Feng J, Liu X, Chen J, Zhou Y, Lv J, Zhou N, Ma J, Tang K, Huang B
Nature cell biology 2024 Nov;26(11):1892-1902
Nature cell biology 2024 Nov;26(11):1892-1902
Angiopoietin 1 Relieves Osteolysis by Promoting Macrophage Mitophagy Through the TBK1-SQSTM1 Pathway to Inhibit AIM2 Inflammasome-Mediated Pyroptosis.
Yin J, Lai P, Zhu L, Ma J
Applied biochemistry and biotechnology 2024 Nov;196(11):7908-7927
Applied biochemistry and biotechnology 2024 Nov;196(11):7908-7927
Cereblon mediates macrophage differentiation and microglial phagocytosis by regulating calpain protease activity.
Zhou L, Sun Q, Cao D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117606
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117606
GBF1 deficiency causes cataracts in human and mouse.
Jia W, Zhang C, Luo Y, Gao J, Yuan C, Zhang D, Zhou X, Tan Y, Wang S, Chen Z, Li G, Zhang X
Human genetics 2024 Nov;143(11):1281-1291
Human genetics 2024 Nov;143(11):1281-1291
SEC31a-ATG9a Interaction Mediates the Recruitment of COPII Vesicles for Autophagosome Formation.
Nie J, Ma S, Wu L, Li Y, Cao J, Li M, Mei P, Cooper PR, Li A, Pei D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(44):e2405127
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(44):e2405127
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus.
Wang Y, Yang Y, Cai Y, Aobulikasimu A, Wang Y, Hu C, Miao Z, Shao Y, Zhao M, Hu Y, Xu C, Chen X, Li Z, Chen J, Wang L, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2407709
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2407709
Enhancing DOX efficacy against NSCLC through UDCA-mediated modulation of the TGF-β/MAPK autophagy pathways.
Li Y, Zhao H, Shen Z, Zheng Y, Jiang Y, Song Y, Cai Y
Scientific reports 2024 Nov 8;14(1):27169
Scientific reports 2024 Nov 8;14(1):27169
Multi-protomics analysis identified host cellular pathways perturbed by tick-borne encephalitis virus infection.
Sui L, Wang W, Guo X, Zhao Y, Tian T, Zhang J, Wang H, Xu Y, Chi H, Xie H, Xu W, Liu N, Zhao L, Song G, Wang Z, Zhang K, Che L, Zhao Y, Wang G, Liu Q
Nature communications 2024 Nov 30;15(1):10435
Nature communications 2024 Nov 30;15(1):10435
Procyanidin C1 ameliorates acidic pH stress induced nucleus pulposus degeneration through SIRT3/FOXO3-mediated mitochondrial dynamics.
Hua W, Xie L, Dong C, Yang G, Chi S, Xu Z, Yang C, Wang H, Wu X
Journal of translational medicine 2024 Nov 27;22(1):1071
Journal of translational medicine 2024 Nov 27;22(1):1071
Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation.
Jiao X, Li Y, Chen Z, Zhang Q, He R, Huang Y, Zuo Z
Science translational medicine 2024 Nov 27;16(775):eadk0636
Science translational medicine 2024 Nov 27;16(775):eadk0636
Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.
Yang S, Fang Z, Duan H, Dong W, Xiao L
Antioxidants (Basel, Switzerland) 2024 Nov 24;13(12)
Antioxidants (Basel, Switzerland) 2024 Nov 24;13(12)
Paeoniflorin Inhibits the Activation of Microglia and Alleviates Depressive Behavior by Regulating SIRT1-NF-kB-NLRP3/Pyroptosis Pathway.
Wang X, Su L, Liu S, He Z, Li J, Zong Y, Chen W, Du R
International journal of molecular sciences 2024 Nov 22;25(23)
International journal of molecular sciences 2024 Nov 22;25(23)
Tripartite motif 25 inhibits protein aggregate degradation during PRRSV infection by suppressing p62-mediated autophagy.
Ren J, Pei Q, Dong H, Wei X, Li L, Duan H, Zhang G, Zhang A
Journal of virology 2024 Nov 19;98(11):e0143724
Journal of virology 2024 Nov 19;98(11):e0143724
EYA3 promotes the tumorigenesis of gastric cancer through activation of the mTORC1 signaling pathway and inhibition of autophagy.
Xu Z, Liu J, Yang M, Huang K
Scientific reports 2024 Nov 16;14(1):28355
Scientific reports 2024 Nov 16;14(1):28355
STAT3 Inhibitor Increases α-Synuclein in PFF-Treated Astroglia Cells by Dysregulating Autophagy and Potentially Affects Exosome Biogenesis.
Luo Y, Zang N, Tang Y, Chen H, Liu H, Wang L, Xu P
Neuromolecular medicine 2024 Nov 13;26(1):46
Neuromolecular medicine 2024 Nov 13;26(1):46
PI3K p85α/HIF-1α accelerates the development of pulmonary arterial hypertension by regulating fatty acid uptake and mitophagy.
Chen C, Qin S, Song X, Wen J, Huang W, Sheng Z, Li X, Cao Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 11;30(1):208
Molecular medicine (Cambridge, Mass.) 2024 Nov 11;30(1):208
Cremastrae Pseudobulbus Pleiones Pseudobulbus (CPPP) Against Non-Small-Cell Lung Cancer: Elucidating Effective Ingredients and Mechanism of Action.
Cao Y, Hao Z, Liu M, Xue J, Wang Y, Wang Y, Li J, Lu Y, Wang C, Shi J
Pharmaceuticals (Basel, Switzerland) 2024 Nov 11;17(11)
Pharmaceuticals (Basel, Switzerland) 2024 Nov 11;17(11)
NLRX1 and STING alleviate renal ischemia-reperfusion injury by regulating LC3 lipidation during mitophagy.
Liao Y, Li P, Hang Q, Chong Y, Long W, Wei X, Sun D, Liu Y
Experimental cell research 2024 Nov 1;443(1):114323
Experimental cell research 2024 Nov 1;443(1):114323
Soybean isoflavones protect dopaminergic neurons from atrazine damage by inhibiting VPS13A to increase autophagy.
Li P, Song W, Xu N, Wang Z, Pang H, Wang D
Ecotoxicology and environmental safety 2024 Nov 1;286:117225
Ecotoxicology and environmental safety 2024 Nov 1;286:117225
Gaudichaudione H ameliorates liver fibrosis and inflammation by targeting NRF2 signaling pathway.
Shi M, Guo Y, Xu J, Yan L, Li X, Liu R, Feng Y, Zhang Y, Zhao Y, Zhang C, Du K, Li M, Zhang Y, Zhang J, Li Z, Ren D, Liu P
Free radical biology & medicine 2024 Nov 1;224:770-784
Free radical biology & medicine 2024 Nov 1;224:770-784
Unconjugated bilirubin promotes uric acid restoration by activating hepatic AMPK pathway.
Zhang Y, Chen Y, Chen X, Gao Y, Luo J, Lu S, Li Q, Li P, Bai M, Jiang T, Zhang N, Zhang B, Chen B, Zhou H, Jiang H, Lin N
Free radical biology & medicine 2024 Nov 1;224:644-659
Free radical biology & medicine 2024 Nov 1;224:644-659
Lanthanum chloride exerts therapeutic potential for chronic kidney disease by suppressing nanohydroxyapatite-induced mitophagy and mitochondria-mediated apoptosis.
Zhu L, Wang LY, Zhang T, Wang QW, Zhang CS, Zhou ZH, Qian JL, Liang Y, Zhou C, Bu R, Su CH, Dong LS, Wang Y, Du XL, Cao XD, Gao J, Liu Y, Li B, Li G
Free radical biology & medicine 2024 Nov 1;224:554-563
Free radical biology & medicine 2024 Nov 1;224:554-563
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
An enzyme-responsive double-locked amonafide prodrug for the treatment of glioblastoma with minimal side effects.
Cheng W, Yang Y, Zhang B, Shao CW, Chen W, Xia R, Sun W, Zhao X, Zhang B, Luo X, James TD, Qian Y
Chemical science 2024 Nov 1;15(46):19336-44
Chemical science 2024 Nov 1;15(46):19336-44
DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level.
Jiang Y, Xu S, Guo M, Lu Z, Wei X, An F, Xin X
Toxicology in vitro : an international journal published in association with BIBRA 2024 May;97:105809
Toxicology in vitro : an international journal published in association with BIBRA 2024 May;97:105809
Dihydroartemisinin eliminates senescent cells by promoting autophagy-dependent ferroptosis via AMPK/mTOR signaling pathway.
Wan X, Li C, Tan YH, Zuo SQ, Deng FM, Sun J, Liu YL
Cell biology international 2024 May;48(5):726-736
Cell biology international 2024 May;48(5):726-736
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
Shen J, Jin J, Huang J, Guo Y, Qian Q
Experimental dermatology 2024 May;33(5):e15094
Experimental dermatology 2024 May;33(5):e15094
SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia.
Sun W, Wang J, Liu C, Gao F, Ou Q, Tian H, Xu J, Zhang J, Li J, Xu J, Jia S, Zhang J, Xu G, Huang J, Jin C, Lu L
International journal of biological macromolecules 2024 May;268(Pt 2):131678
International journal of biological macromolecules 2024 May;268(Pt 2):131678
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Zhang Z, Kang Z, Deng K, Li J, Liu Z, Huang X, Wang F, Fan Y
Journal of cellular physiology 2024 May;239(5):e31226
Journal of cellular physiology 2024 May;239(5):e31226
Platelet factor 4 promotes deep venous thrombosis by regulating the formation of neutrophil extracellular traps.
Li W, Chi D, Ju S, Zhao X, Li X, Zhao J, Xie H, Li Y, Jin J, Mang G, Dong Z
Thrombosis research 2024 May;237:52-63
Thrombosis research 2024 May;237:52-63
Transcription factor FOXM1 specifies chromatin DNA to extracellular vesicles.
Zhang Y, Ding N, Li Y, Ouyang M, Fu P, Peng Y, Tan Y
Autophagy 2024 May;20(5):1054-1071
Autophagy 2024 May;20(5):1054-1071
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis.
Wang Q, Liu C, Chen M, Zhao J, Wang D, Gao P, Zhang C, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116560
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116560
Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.
Shen X, Xia Y, Lu H, Zheng P, Wang J, Chen Y, Xu C, Qiu C, Zhang Y, Xiao Z, Zou P, Cui R, Ni D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116507
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116507
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
Aucubin alleviates doxorubicin-induced cardiotoxicity through crosstalk between NRF2 and HIPK2 mediating autophagy and apoptosis.
Li W, Cao J, Zhang Y, Ling G, Tan N, Wei Y, Zhang Y, Wang X, Qian W, Jiang J, Zhang J, Wang W, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155473
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155473
Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway.
Chen K, Jin HJ, Wu ZH, Zhang BF, Wu J, Huang ZY, Huang YP, Lu XW, Zheng XT
Molecular medicine (Cambridge, Mass.) 2024 May 8;30(1):58
Molecular medicine (Cambridge, Mass.) 2024 May 8;30(1):58
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Xue P, Zhuang H, Bai T, Zeng X, Deng J, Shao S, Yan S
Journal of nanobiotechnology 2024 May 8;22(1):228
Journal of nanobiotechnology 2024 May 8;22(1):228
Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity.
Zhao M, Ren Z, Zhao A, Tang Y, Kuang J, Li M, Chen T, Wang S, Wang J, Zhang H, Wang J, Zhang T, Zeng J, Liu X, Xie G, Liu P, Sun N, Bao T, Nie T, Lin J, Liu P, Zheng Y, Zheng X, Liu T, Jia W
Cell metabolism 2024 May 7;36(5):1000-1012.e6
Cell metabolism 2024 May 7;36(5):1000-1012.e6
p20BAP31 Induces Autophagy in Colorectal Cancer Cells by Promoting PERK-Mediated ER Stress.
Jiang X, Li G, Zhu B, Yang J, Cui S, Jiang R, Wang B
International journal of molecular sciences 2024 May 7;25(10)
International journal of molecular sciences 2024 May 7;25(10)
Varespladib mitigates acute liver injury via suppression of excessive mitophagy on Naja atra envenomed mice by inhibiting PLA(2).
Zhao W, Liu J, Wang S, Tao Q, Lei Q, Huang C
Toxicon : official journal of the International Society on Toxinology 2024 May 6;242:107694
Toxicon : official journal of the International Society on Toxinology 2024 May 6;242:107694
Inhibition of NLRP3 inflammasome by MCC950 under hypoxia alleviates photoreceptor apoptosis via inducing autophagy in Müller glia.
Gao S, Li N, Lin Z, Zhong Y, Wang Y, Shen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23671
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23671
Oxidative medicine and cellular longevity the role and mechanism of NCOA4 in ferroptosis induced by intestinal ischemia reperfusion.
Li K, Wang A, Diao Y, Fan S
International immunopharmacology 2024 May 30;133:112155
International immunopharmacology 2024 May 30;133:112155
Chondroprotective effects of Apolipoprotein D in knee osteoarthritis mice through the PI3K/AKT/mTOR signaling pathway.
Zhang G, Huang C, Wang R, Guo J, Qin Y, Lv S
International immunopharmacology 2024 May 30;133:112005
International immunopharmacology 2024 May 30;133:112005
Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy.
Li YP, Huang ZJ, He QK, Li YX, Zhao XP, Ma ZQ, Qin MJ, Chen AW, Wei Q, Wang Y, Lu CH
Journal of proteome research 2024 May 3;23(5):1713-1724
Journal of proteome research 2024 May 3;23(5):1713-1724
SS-31 inhibits the inflammatory response by increasing ATG5 and promoting autophagy in lipopolysaccharide-stimulated HepG2 cells.
Mo Y, Deng S, Ai Y, Li W
Biochemical and biophysical research communications 2024 May 28;710:149887
Biochemical and biophysical research communications 2024 May 28;710:149887
Label-Free Three-Dimensional Morphological Characterization of Cell Death Using Holographic Tomography.
Huang CH, Lai YJ, Chen LN, Hung YH, Tu HY, Cheng CJ
Sensors (Basel, Switzerland) 2024 May 26;24(11)
Sensors (Basel, Switzerland) 2024 May 26;24(11)
Pectinose induces cell cycle arrest in luminal A and triple-negative breast cancer cells by promoting autophagy through activation of the p38 MAPK signaling pathway.
Yu S, Yue Z, Liu Q
BMC cancer 2024 May 24;24(1):639
BMC cancer 2024 May 24;24(1):639
Galectin-receptor interaction: a key player in liver fibrosis induced by Schistosoma japonicum infection.
Huang Z, Liu X, Huang S, Lu F
Parasites & vectors 2024 May 20;17(1):232
Parasites & vectors 2024 May 20;17(1):232
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
Li Y, Zhao K, Hu Y, Yang F, Li P, Liu Y
iScience 2024 May 17;27(5):109764
iScience 2024 May 17;27(5):109764
D-arabinose induces cell cycle arrest by promoting autophagy via p38 MAPK signaling pathway in breast cancer.
Tang Z, Song H, Qin S, Tian Z, Zhang C, Zhou Y, Cai R, Zhu Y
Scientific reports 2024 May 16;14(1):11219
Scientific reports 2024 May 16;14(1):11219
The polysaccharides from Balanophora polyandra enhanced neuronal autophagy to ameliorate brain function decline in natural aging mice through the PI3K/AKT/mTOR signaling pathway.
Zhong W, Chen J, He Y, Xiao L, Yuan C
Neuroreport 2024 May 15;35(8):509-517
Neuroreport 2024 May 15;35(8):509-517
Cadmium exposure induced neuronal ferroptosis and cognitive deficits via the mtROS-ferritinophagy pathway.
Wang D, Wu Y, Zhou X, Liang C, Ma Y, Yuan Q, Wu Z, Hao X, Zhu X, Li X, Shi J, Chen J, Fan H
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123958
Environmental pollution (Barking, Essex : 1987) 2024 May 15;349:123958
Sialyltransferase ST3GAL6 silencing reduces α2,3-sialylated glycans to regulate autophagy by decreasing HSPB8-BAG3 in the brain with hepatic encephalopathy.
Li X, Xiao Y, Li P, Zhu Y, Guo Y, Bian H, Li Z
Journal of Zhejiang University. Science. B 2024 May 15;25(6):485-498
Journal of Zhejiang University. Science. B 2024 May 15;25(6):485-498
Mangiferin attenuates lipopolysaccharide-induced neuronal injuries in primary cultured hippocampal neurons.
Tan H, Liang D, Lu N, Zhang J, Zhang S, Tan G
Aging 2024 May 15;16(10):8645-8656
Aging 2024 May 15;16(10):8645-8656
Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells.
Dong M, Zhang T, Liang X, Cheng X, Shi F, Yuan H, Zhang F, Jiang Q, Wang X
Biochemical and biophysical research communications 2024 May 14;708:149815
Biochemical and biophysical research communications 2024 May 14;708:149815
Glycosides of Buyang Huanwu decoction inhibits inflammation associated with cerebral ischemia-reperfusion via the PINK1/Parkin mitophagy pathway.
Jiao K, Lai Z, Cheng Q, Yang Z, Liao W, Liao Y, Long H, Sun R, Lang T, Shao L, Deng C, She Y
Journal of ethnopharmacology 2024 May 10;325:117766
Journal of ethnopharmacology 2024 May 10;325:117766
MicroRNA-144-3p Inhibits Host Lipid Catabolism and Autophagy by Targeting PPARα and ABCA1 During Mycobacterium Tuberculosis Infection.
Wu J, Zhang Y, Tang H, Ye BC
ACS infectious diseases 2024 May 10;10(5):1654-1663
ACS infectious diseases 2024 May 10;10(5):1654-1663
TIMP2 protects against sepsis-associated acute kidney injury by cAMP/NLRP3 axis-mediated pyroptosis.
Xu D, Jiang J, Liu Y, Pang J, Suo J, Li Y, Peng Z
American journal of physiology. Cell physiology 2024 May 1;326(5):C1353-C1366
American journal of physiology. Cell physiology 2024 May 1;326(5):C1353-C1366
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Zhang Z, Song B, Wei H, Liu Y, Zhang W, Yang Y, Sun B
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
Autophagy activity is increased in the cumulus cells of women with poor ovarian response.
Zhu JR, Zhu WJ, Li T, Ou JP
Taiwanese journal of obstetrics & gynecology 2024 Mar;63(2):205-213
Taiwanese journal of obstetrics & gynecology 2024 Mar;63(2):205-213
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.
Ling M, Qian H, Guo H
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265
Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia.
Li Z, Zhang F, Huang L, Deng J, Pan Y, Xu T, Liu J, Gao N, Duan R, Shao C, Wu C, Wang M, Lu L
Neurochemical research 2024 Mar;49(3):670-683
Neurochemical research 2024 Mar;49(3):670-683
Local delivery of EGFR(+)NSCs-derived exosomes promotes neural regeneration post spinal cord injury via miR-34a-5p/HDAC6 pathway.
Qin T, Li C, Xu Y, Qin Y, Jin Y, He R, Luo Z, Zhao J, Duan C, Lu H, Cao Y, Hu J
Bioactive materials 2024 Mar;33:424-443
Bioactive materials 2024 Mar;33:424-443
Mitochondrial-targeting and NIR-responsive Mn(3)O(4)@PDA@Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate osteoarthritis.
Li Y, Yang J, Chen X, Hu H, Lan N, Zhao J, Zheng L
Biomaterials 2024 Mar;305:122449
Biomaterials 2024 Mar;305:122449
RACK1 promotes autophagy via the PERK signaling pathway to protect against traumatic brain injury in rats.
Ni H, Kan X, Rui Q, Zhang Y, Zhai W, Zhang B, Yu Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14691
CNS neuroscience & therapeutics 2024 Mar;30(3):e14691
Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Wang J
Free radical biology & medicine 2024 Mar;214:80-86
Free radical biology & medicine 2024 Mar;214:80-86
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Jia C, Wu Y, Gao F, Liu W, Li N, Chen Y, Sun L, Wang S, Yu C, Bao Y, Song Z
Free radical biology & medicine 2024 Mar;214:2-18
Free radical biology & medicine 2024 Mar;214:2-18
CDK12 inhibition upregulates ATG7 triggering autophagy via AKT/FOXO3 pathway and enhances anti-PD-1 efficacy in colorectal cancer.
Wu Z, Zhang W, Chen L, Wang T, Wang X, Shi H, Zhang L, Zhong M, Shi X, Mao X, Chen H, Li Q
Pharmacological research 2024 Mar;201:107097
Pharmacological research 2024 Mar;201:107097
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Wen T, Xie J, Ma L, Hao Z, Zhang W, Wu T, Li L
The American journal of pathology 2024 Mar;194(3):369-383
The American journal of pathology 2024 Mar;194(3):369-383
Corydecusines A-H, new phthalideisoquinoline hemicetal alkaloids from the bulbs of Corydalis decumbens inhibit Tau pathology by activating autophagy mediated by AMPK-ULK1 pathway.
Li S, Luo RC, Liang ZZ, Zhang BD, Wei YL, Wen HY, Dong J, Li XY, Guo LL, Hao XJ, Li N, Zhang Y
Bioorganic chemistry 2024 Mar;144:107166
Bioorganic chemistry 2024 Mar;144:107166
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Hu R, Wang XJ, Chen S, Huang Y, Yu J
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Wang Q, He Z, Zhu J, Hu M, Yang L, Yang H
BMC biotechnology 2024 Mar 8;24(1):13
BMC biotechnology 2024 Mar 8;24(1):13
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy.
Liu ZD, Shi YH, Xu QC, Zhao GY, Zhu YQ, Li FX, Ma MJ, Ye JY, Huang XT, Wang XY, Xu X, Wang JQ, Zhao W, Yin XY
Cancer letters 2024 Mar 31;585:216640
Cancer letters 2024 Mar 31;585:216640
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression.
Wang X, Liu Z, Deng S, Zhou J, Li X, Huang J, Chen J, Ji C, Deng Y, Hu Y
International immunopharmacology 2024 Mar 30;130:111755
International immunopharmacology 2024 Mar 30;130:111755
Metformin alleviates junctional epithelium senescence via the AMPK/SIRT1/autophagy pathway in periodontitis induced by hyperglycemia.
Ye X, Wang Y, Tian Y, Bi R, Li M, Yang C, Zhang L, Gao Y
Heliyon 2024 Mar 30;10(6):e27478
Heliyon 2024 Mar 30;10(6):e27478
Integrated network pharmacology and phosphoproteomic analyses of Baichanting in Parkinson's disease model mice.
Gao X, Fu J, Yu D, Lu F, Liu S
Heliyon 2024 Mar 30;10(6):e26916
Heliyon 2024 Mar 30;10(6):e26916
ALKBH5 suppresses autophagic flux via N6-methyladenosine demethylation of ZKSCAN3 mRNA in acute pancreatitis.
Zhang T, Zhu S, Huang GW
World journal of gastroenterology 2024 Mar 28;30(12):1764-1776
World journal of gastroenterology 2024 Mar 28;30(12):1764-1776
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Yang Y, Qiu W, Xiao J, Sun J, Ren X, Jiang L
Journal of translational medicine 2024 Mar 26;22(1):309
Journal of translational medicine 2024 Mar 26;22(1):309
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Zhao Z, Han W, Huang G, He Y, Zuo X, Hong L
Experimental cell research 2024 Mar 15;436(2):113974
Experimental cell research 2024 Mar 15;436(2):113974
Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis.
Chen N, Wan X, Cheng S, Tang G, Xia D, Xu Y, Shen Y
Ecotoxicology and environmental safety 2024 Mar 15;273:116095
Ecotoxicology and environmental safety 2024 Mar 15;273:116095
Identification of a ferritinophagy inducer via sinomenine modification for the treatment of colorectal cancer.
Zhu L, Chen C, Cai Y, Li Y, Gong L, Zhu T, Kong L, Luo J
European journal of medicinal chemistry 2024 Mar 15;268:116250
European journal of medicinal chemistry 2024 Mar 15;268:116250
Cyclin-dependent kinase inhibitor 1A inhibits pyroptosis to enhance human lung adenocarcinoma cell radioresistance by promoting DNA repair.
Li J, Liu T, Tang N, Lin S, Zhang F, Yuan W, Zhang T, Deng SH, Wu DM, Xu Y
Heliyon 2024 Mar 15;10(5):e26975
Heliyon 2024 Mar 15;10(5):e26975
Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Enhances foxo1-Mediated Lipophagy to Remodel Lipid Metabolism in Zebrafish Liver.
Zhou Y, Li F, Fu K, Zhang Y, Zheng N, Tang H, Xu Z, Luo L, Han J, Yang L, Zhou B
Environmental science & technology 2024 Mar 12;58(10):4581-4593
Environmental science & technology 2024 Mar 12;58(10):4581-4593
Manganese disrupts the maturation and degradation of axonal autophagosome leading to hippocampal synaptic toxicity in mice via the activation of LRRK2 on phosphorylation of Rab10.
Ma Z, Liu K, Zhang RF, Xie ZX, Liu W, Xu B
The Science of the total environment 2024 Mar 10;915:170021
The Science of the total environment 2024 Mar 10;915:170021
Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
Luo X, Zhang J, Guo C, Jiang N, Zhang F, Jiao Q, Xu K, Yang J, Qu G, Lv XB, Zhang Z
Gene 2024 Mar 10;898:148110
Gene 2024 Mar 10;898:148110
NPC1 promotes autophagy with tumor promotion and acts as a prognostic model for hepatocellular carcinoma.
Xu J, Chen F, Zhu W, Zhang W
Gene 2024 Mar 1;897:148050
Gene 2024 Mar 1;897:148050
Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR pathway in human granulosa cell line KGN.
Gao M, Shen H, Li Q, Gu X, Jia T, Wang Y
Environmental pollution (Barking, Essex : 1987) 2024 Mar 1;344:123333
Environmental pollution (Barking, Essex : 1987) 2024 Mar 1;344:123333
Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD.
Wang J, He W, Yue H, Zhao P, Li J
Journal of ethnopharmacology 2024 Mar 1;321:117537
Journal of ethnopharmacology 2024 Mar 1;321:117537
Tangzhiqing decoction attenuates cognitive dysfunction of mice with type 2 diabetes by regulating AMPK/mTOR autophagy signaling pathway.
Yao W, Zhang Q, Zhao Y, Xu X, Zhang S, Wang X
Journal of ethnopharmacology 2024 Mar 1;321:117536
Journal of ethnopharmacology 2024 Mar 1;321:117536
Sirt3 Protects Retinal Pigment Epithelial Cells From High Glucose-Induced Injury by Promoting Mitophagy Through the AMPK/mTOR/ULK1 Pathway.
Yang W, Qiu C, Lv H, Zhang Z, Yao T, Huang L, Wu G, Zhang X, Chen J, He Y
Translational vision science & technology 2024 Mar 1;13(3):19
Translational vision science & technology 2024 Mar 1;13(3):19
Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated LC3B transcription in NSCLC.
Ni H, Tang S, Lu G, Niu Y, Xu J, Zhang H, Hu J, Shen HM, Wu Y, Xia D
Life science alliance 2024 Jun;7(6)
Life science alliance 2024 Jun;7(6)
Punicalagin Ameliorates Diabetic Liver Injury by Inhibiting Pyroptosis and Promoting Autophagy via Modulation of the FoxO1/TXNIP Signaling Pathway.
Tan X, Long Y, Zhang R, Zhang Y, You Z, Yang L
Molecular nutrition & food research 2024 Jun;68(12):e2300912
Molecular nutrition & food research 2024 Jun;68(12):e2300912
Hsa_circ_0001402 alleviates vascular neointimal hyperplasia through a miR-183-5p-dependent regulation of vascular smooth muscle cell proliferation, migration, and autophagy.
Lin JJ, Chen R, Yang LY, Gong M, Du MY, Mu SQ, Jiang ZA, Li HH, Yang Y, Wang XH, Wang SF, Liu KX, Cao SH, Wang ZY, Zhao AQ, Yang SY, Li C, Sun SG
Journal of advanced research 2024 Jun;60:93-110
Journal of advanced research 2024 Jun;60:93-110
Beclin 1 Haploinsufficiency Ameliorates High-Fat Diet-Induced Myocardial Injury via Inhibiting Alternative Mitophagy.
Zeng X, Sun J, Li F, Peng L, Zhang C, Jiang X, Zha L, Rathinasabapathy A, Ren J, Yu Z, Wang L, Liu X
Antioxidants & redox signaling 2024 Jun;40(16-18):906-925
Antioxidants & redox signaling 2024 Jun;40(16-18):906-925
Lysine specific demethylase 1 inhibits sodium arsenite activation of HSCs by regulating SESN2/AMPK/ULK1 signaling pathway activity.
Zhang Y, Tian T, Liang C, Wang J, Zhang J, Tian S, Xie R, Yang T, Han B
Environmental toxicology 2024 Jun;39(6):3563-3577
Environmental toxicology 2024 Jun;39(6):3563-3577
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC3.
Shi X, Yao J, Huang Y, Wang Y, Jiang X, Wang Z, Zhang M, Zhang Y, Liu X
The Journal of biological chemistry 2024 Jun;300(6):107335
The Journal of biological chemistry 2024 Jun;300(6):107335
TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA.
Liu H, Zhen C, Xie J, Luo Z, Zeng L, Zhao G, Lu S, Zhuang H, Fan H, Li X, Liu Z, Lin S, Jiang H, Chen Y, Cheng J, Cao Z, Dai K, Shi J, Wang Z, Hu Y, Meng T, Zhou C, Han Z, Huang H, Zhou Q, He P, Feng D
Nature cell biology 2024 Jun;26(6):878-891
Nature cell biology 2024 Jun;26(6):878-891
A Key regulatory protein QRICH2 governing sperm function with profound antioxidant properties, enhancing sperm viability.
Zhang G, Xiong D, Ye F, Zhao Y, Du X, Zhi W, Liu F, Zeng J, Xu W, Liu W, Shi Y
Reproductive biology 2024 Jun;24(2):100881
Reproductive biology 2024 Jun;24(2):100881
Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy.
Su L, Guo P, Guo X, He Z, Zhao Y, Zong Y, Li J, Chen W, DU R
Chinese journal of natural medicines 2024 Jun;22(6):515-529
Chinese journal of natural medicines 2024 Jun;22(6):515-529
Reactive Oxygen Species-Mediated Mitophagy and Cell Apoptosis are Involved in the Toxicity of Aluminum Chloride Exposure in GC-2spd.
Peng HX, Chai F, Chen KH, Huang YX, Wei GJ, Yuan H, Pang YF, Luo SH, Wang CF, Chen WC
Biological trace element research 2024 Jun;202(6):2616-2629
Biological trace element research 2024 Jun;202(6):2616-2629
Modulating synovial macrophage pyroptosis and mitophagy interactions to mitigate osteoarthritis progression using functionalized nanoparticles.
Qi W, Jin L, Huang S, Aikebaier A, Xue S, Wang Q, Chen Q, Lu Y, Ding C
Acta biomaterialia 2024 Jun;181:425-439
Acta biomaterialia 2024 Jun;181:425-439
Enhancement of autophagy can alleviate oxidative stress, inflammation, and apoptosis induced by ammonia stress in yellow catfish Pelteobagrus fulvidraco.
Li X, Wang S, Zhang M, Li M
Fish & shellfish immunology 2024 Jun;149:109582
Fish & shellfish immunology 2024 Jun;149:109582
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Sheng X, Wang MM, Zhang GD, Su Y, Fang HB, Yu ZH, Su Z
Bioorganic chemistry 2024 Jun;147:107325
Bioorganic chemistry 2024 Jun;147:107325
PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
Geng Q, Xu J, Cao X, Wang Z, Jiao Y, Diao W, Wang X, Wang Z, Zhang M, Zhao L, Yang L, Deng T, Fan B, Xu Y, Jia L, Xiao C
Journal of autoimmunity 2024 Jun;146:103214
Journal of autoimmunity 2024 Jun;146:103214
Total paeony glycoside relieves neuroinflammation to exert antidepressant effect via the interplay between NLRP3 inflammasome, pyroptosis and autophagy.
Su L, Lu H, Zhang D, Zhu X, Li J, Zong Y, Zhao Y, He Z, Chen W, Du R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155519
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155519
Exosomes from adipose-derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ-Rps5/miR-124-3p axis.
Yin D, Shen G
Immunity, inflammation and disease 2024 Jun;12(6):e1274
Immunity, inflammation and disease 2024 Jun;12(6):e1274
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Qi Z, Bai X, Wu L, Zhang P, Guo Z, Yu Y
Journal of translational medicine 2024 Jun 6;22(1):538
Journal of translational medicine 2024 Jun 6;22(1):538
Hypoxia-mediated programmed cell death is involved in the formation of wooden breast in broilers.
Zhang X, Xing T, Zhang L, Zhao L, Gao F
Journal of animal science and biotechnology 2024 Jun 6;15(1):77
Journal of animal science and biotechnology 2024 Jun 6;15(1):77
Microbial metabolite sodium butyrate enhances the anti-tumor efficacy of 5-fluorouracil against colorectal cancer by modulating PINK1/Parkin signaling and intestinal flora.
Li Y, He P, Chen Y, Hu J, Deng B, Liu C, Yu B, Dong W
Scientific reports 2024 Jun 6;14(1):13063
Scientific reports 2024 Jun 6;14(1):13063
Pongamol Alleviates Neuroinflammation and Promotes Autophagy in Alzheimer's Disease by Regulating the Akt/mTOR Signaling Pathway.
Hu K, Wu S, Xu J, Zhang Y, Zhang Y, Wu X, Miao J, Yao Y, Zhu S, Chen G, Ren J
Journal of agricultural and food chemistry 2024 Jun 6;
Journal of agricultural and food chemistry 2024 Jun 6;
Baicalin reduced injury of and autophagy-related gene expression in RAW264.7 cells infected with H6N6 avian influenza virus.
Yang X, Li J, Shan C, Song X, Yang J, Xu H, Ou D
Heliyon 2024 Jun 30;10(12):e32645
Heliyon 2024 Jun 30;10(12):e32645
Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease.
Pan B, Teng Y, Wang R, Chen D, Chen H
BMC medical genomics 2024 Jun 3;17(1):152
BMC medical genomics 2024 Jun 3;17(1):152
A specific super-enhancer actuated by berberine regulates EGFR-mediated RAS-RAF1-MEK1/2-ERK1/2 pathway to induce nasopharyngeal carcinoma autophagy.
Wu Y, Jia Q, Tang Q, Chen L, Deng H, He Y, Tang F
Cellular & molecular biology letters 2024 Jun 28;29(1):92
Cellular & molecular biology letters 2024 Jun 28;29(1):92
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
Lin Y, Wang D, Li B, Wang J, Xu L, Sun X, Ji K, Yan C, Liu F, Zhao Y
JCI insight 2024 Jun 25;9(15)
JCI insight 2024 Jun 25;9(15)
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Lei LM, Li FX, Lin X, Xu F, Shan SK, Guo B, Zheng MH, Tang KX, Wang Y, Xu QS, Ouyang WL, Duan JY, Wu YY, Cao YC, Zhou ZA, He SY, Wu YL, Chen X, Lin ZJ, Pan Y, Yuan LQ, Li ZH
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Journal of nanobiotechnology 2024 Jun 23;22(1):361
MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice.
Ma H, Ou ZL, Alaeiilkhchi N, Cheng YQ, Chen K, Chen JY, Guo RQ, He MY, Tang SY, Zhang X, Huang ZP, Liu J, Liu J, Zhu QA, Huang ZC, Jiang H
Lipids in health and disease 2024 Jun 22;23(1):194
Lipids in health and disease 2024 Jun 22;23(1):194
Identification of osteoblastic autophagy-related genes for predicting diagnostic markers in osteoarthritis.
Cai R, Jiang Q, Chen D, Feng Q, Liang X, Ouyang Z, Liao W, Zhang R, Fang H
iScience 2024 Jun 21;27(6):110130
iScience 2024 Jun 21;27(6):110130
Inhibiting Pink1/Parkin-mediated mitophagy enhances the anticancer effects of quercetin in hepatocellular carcinomaf.
Chen F
Biochemical and biophysical research communications 2024 Jun 18;712-713:149899
Biochemical and biophysical research communications 2024 Jun 18;712-713:149899
β-elemene promotes microglial M2-like polarization against ischemic stroke via AKT/mTOR signaling axis-mediated autophagy.
Zhao Q, Chen L, Zhang X, Yang H, Li Y, Li P
Chinese medicine 2024 Jun 15;19(1):86
Chinese medicine 2024 Jun 15;19(1):86
Heyingwuzi formulation alleviates diabetic retinopathy by promoting mitophagy via the HIF-1α/BNIP3/NIX axis.
Wu JJ, Zhang SY, Mu L, Dong ZG, Zhang YJ
World journal of diabetes 2024 Jun 15;15(6):1317-1339
World journal of diabetes 2024 Jun 15;15(6):1317-1339
TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
Wu J, Jiang L, Wang S, Peng L, Zhang R, Liu Z
International immunopharmacology 2024 Jun 15;134:112235
International immunopharmacology 2024 Jun 15;134:112235
Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism.
Wang X, Kang J, Li X, Wu P, Huang Y, Duan Y, Feng J, Wang J
Journal of ethnopharmacology 2024 Jun 12;327:118016
Journal of ethnopharmacology 2024 Jun 12;327:118016
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
Bai J, Feng Z, Chen Y, Li Y, Zhang L, Li L
Discover oncology 2024 Jun 10;15(1):217
Discover oncology 2024 Jun 10;15(1):217
3-MCPD Induces Renal Cell Pyroptosis and Inflammation by Inhibiting ESCRT-III-Mediated Cell Repair and Mitophagy.
Zhang R, Guan S, Meng Z, Deng X, Lu J
Journal of agricultural and food chemistry 2024 Jun 10;
Journal of agricultural and food chemistry 2024 Jun 10;
Intestinal microbiota via NLRP3 inflammasome dependent neuronal pyroptosis mediates anxiety-like behaviour in mice exposed to 3.5 GHz radiofrequency radiation.
Zhou GQ, Wang X, Gao P, Qin TZ, Guo L, Zhang ZW, Huang ZF, Lin JJ, Jing YT, Wang HN, Wang CP, Ding GR
The Science of the total environment 2024 Jun 1;927:172391
The Science of the total environment 2024 Jun 1;927:172391
Hsa_circ_0096157 silencing suppresses autophagy and reduces cisplatin resistance in non-small cell lung cancer by weakening the Nrf2/ARE signaling pathway.
Lu H, Kong J, Cai S, Huang H, Luo J, Liu L
Molecular biology reports 2024 Jun 1;51(1):703
Molecular biology reports 2024 Jun 1;51(1):703
Exposure to nicotine regulates prostaglandin E2 secretion and autophagy of granulosa cells to retard follicular maturation in mammals.
Zhou X, He Y, Quan H, Yang J, Li S, Jiang Y, Li J, Yuan X
Ecotoxicology and environmental safety 2024 Jun 1;277:116358
Ecotoxicology and environmental safety 2024 Jun 1;277:116358
A novel SLC3A2-targeting antibody-drug conjugate exerts potent antitumor efficacy in head and neck squamous cell cancer.
Zheng M, Wang Z, Li M, Yang N, Lu H, Zhang Z, Dong Y, Chen Y, Zhu Z, Tong A, Yang H
Translational oncology 2024 Jul;45:101981
Translational oncology 2024 Jul;45:101981
TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Xing H, Xu P, Ma Y, Li T, Zhang Y, Ding X, Liu L, Keerman M, Niu Q
Environmental toxicology 2024 Jul;39(7):3779-3789
Environmental toxicology 2024 Jul;39(7):3779-3789
Mechanism Research of DHEA Treatment Improving Diminished Ovarian Reserve by Attenuating the AMPK-SIRT1 Signaling and Mitophagy.
Ma Q, Shen M, Wu J, Ye C, Tan Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 Jul;31(7):2059-2072
Reproductive sciences (Thousand Oaks, Calif.) 2024 Jul;31(7):2059-2072
Heme oxygenase activates calcium release from the endoplasmic reticulum of bovine mammary epithelial cells to promote TFEB entry into the nucleus to reduce the intracellular load of Mycoplasma bovis.
Xu M, Zhu Z, Meng S, Li H, Wang A, Barkema HW, Cobo ER, Kastelic JP, Khan MA, Gao J, Han B
Microbiological research 2024 Jul;284:127727
Microbiological research 2024 Jul;284:127727
Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition.
Zhang GD, Wang MM, Su Y, Fang H, Xue XL, Liu HK, Su Z
Journal of inorganic biochemistry 2024 Jul;256:112574
Journal of inorganic biochemistry 2024 Jul;256:112574
Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro.
Ping Z, Shuxia Z, Xinyu D, Kehe H, Xingxiang C, Chunfeng W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jul;189:114714
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Jul;189:114714
The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation.
Li J, Ng KW, Sung CC, Chung KKK
Journal of neurochemistry 2024 Jul;168(7):1215-1236
Journal of neurochemistry 2024 Jul;168(7):1215-1236
Neonatal Exposure to Polystyrene Nanoplastics Impairs Microglia-Mediated Synaptic Pruning and Causes Social Behavioral Defects in Adulthood.
Zou L, Xu X, Wang Y, Lin F, Zhang C, Liu R, Hou X, Wang J, Jiang X, Zhang Q, Li L
Environmental science & technology 2024 Jul 9;58(27):11945-11957
Environmental science & technology 2024 Jul 9;58(27):11945-11957
Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.
Thakur A, Chu YH, Rao NV, Mathew J, Grewal AS, Prabakaran P, Guru S, Liou JP, Pan CH, Nepali K
European journal of medicinal chemistry 2024 Jul 5;273:116507
European journal of medicinal chemistry 2024 Jul 5;273:116507
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
Huang R, Liu L, Shen K, Duan C, Fan Z
Journal of integrative neuroscience 2024 Jul 5;23(7):124
Journal of integrative neuroscience 2024 Jul 5;23(7):124
A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism.
Su S, Liu L, Fu Q, Ma M, Yang N, Pan T, Geng S, Yu XF, Zhu J
Journal of nanobiotechnology 2024 Jul 4;22(1):391
Journal of nanobiotechnology 2024 Jul 4;22(1):391
Exploring the Molecular Mechanism of Schisandrin C for the Treatment of Atherosclerosis via the PI3K/AKT/mTOR Autophagy Pathway.
Duan H, Li H, Liu T, Chen Y, Luo M, Shi Y, Zhou J, Rashed MMA, Zhai K, Li L, Wei Z
ACS omega 2024 Jul 30;9(30):32920-32930
ACS omega 2024 Jul 30;9(30):32920-32930
The cellular adaptor GULP1 interacts with ATG14 to potentiate autophagy and APP processing.
Chau DD, Yu Z, Chan WWR, Yuqi Z, Chang RCC, Ngo JCK, Chan HYE, Lau KF
Cellular and molecular life sciences : CMLS 2024 Jul 30;81(1):323
Cellular and molecular life sciences : CMLS 2024 Jul 30;81(1):323
Mdivi-1 alleviates ferroptosis induced by hypoxia combined with propofol in HT22 cells by inhibiting excessive mitophagy.
Yang S, Xu Y, Ahmad T, Deng Q, Gan Z, Yang Y, Yun H, Dong Z, Tu S
Molecular biology reports 2024 Jul 30;51(1):870
Molecular biology reports 2024 Jul 30;51(1):870
LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.
Wu HH, Du JM, Liu P, Meng FL, Li YY, Li WJ, Wang SX, Du NL, Zheng Y, Zhang L, Wang HY, Liu YR, Song CH, Ni X, Li Y, Su GH
International immunopharmacology 2024 Jul 30;136:112338
International immunopharmacology 2024 Jul 30;136:112338
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zhang Z, Hu J
Journal of translational medicine 2024 Jul 3;22(1):617
Journal of translational medicine 2024 Jul 3;22(1):617
Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.
Chen Y, Bao S, Wang Z, Fang Z, Tang H
European journal of medical research 2024 Jul 26;29(1):387
European journal of medical research 2024 Jul 26;29(1):387
Drp1 Aggravates Copper Nanoparticle-Induced ER-Phagy by Disturbing Mitochondria-Associated Membranes in Chicken Hepatocytes.
Li Q, Guo P, Wang S, Su L, Yu W, Guo J, Hu L, Zhang H, Pan J, Tang Z, Liao J
Journal of agricultural and food chemistry 2024 Jul 24;72(29):16506-16518
Journal of agricultural and food chemistry 2024 Jul 24;72(29):16506-16518
Nur77 improves ovarian function in reproductive aging mice by activating mitophagy and inhibiting apoptosis.
Yao Y, Wang B, Yu K, Song J, Wang L, Zhang X, Li Y
Reproductive biology and endocrinology : RB&E 2024 Jul 23;22(1):86
Reproductive biology and endocrinology : RB&E 2024 Jul 23;22(1):86
Microglial AKAP8L: a key mediator in diabetes-associated cognitive impairment via autophagy inhibition and neuroinflammation triggering.
Zhang WY, Wei QQ, Zhang T, Wang CS, Chen J, Wang JH, Xie X, Jiang P
Journal of neuroinflammation 2024 Jul 20;21(1):177
Journal of neuroinflammation 2024 Jul 20;21(1):177
Defective ferritinophagy and imbalanced iron metabolism in PBDE-47-triggered neuronal ferroptosis and salvage by Canolol.
Wang Y, Li X, Qu T, Huang F, Xu J, Gao H, Zhang S
The Science of the total environment 2024 Jul 15;934:173118
The Science of the total environment 2024 Jul 15;934:173118
Short-chain fatty acids mitigate Methamphetamine-induced hepatic injuries in a Sigma-1 receptor-dependent manner.
Zhang KK, Yang JZ, Cheng CH, Wan JY, Chen YC, Zhou HQ, Zheng DK, Lan ZX, You QH, Wang Q, Sun J
Ecotoxicology and environmental safety 2024 Jul 15;280:116538
Ecotoxicology and environmental safety 2024 Jul 15;280:116538
Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota.
Han L, Chen W, Li J, Zhao Y, Zong Y, He Z, Du R
Brain research 2024 Jul 15;1835:148932
Brain research 2024 Jul 15;1835:148932
Targeting of G protein-coupled receptor 39 alleviates angiotensin II-induced renal damage by reducing ribonucleotide reductase M2.
Hua D, Huang W, Xu W, Zhang Y, Xie Q, Li P, Sheng Y
Experimental cell research 2024 Jul 1;440(1):114102
Experimental cell research 2024 Jul 1;440(1):114102
Sevoflurane enhances autophagy via Rac1 to attenuate lung ischaemia‒reperfusion injury.
Ding X, Gao X, Ren A, Xu J, Jiang X, Liang X, Xie K, Zhou Y, Hu C, Huang D
Chemico-biological interactions 2024 Jul 1;397:111078
Chemico-biological interactions 2024 Jul 1;397:111078
HIF-1α Contributes to Hypoxia-induced VSMC Proliferation and Migration by Regulating Autophagy in Type A Aortic Dissection.
Huang B, Chen N, Chen Z, Shen J, Zhang H, Wang C, Sun Y
Advanced biology 2024 Jan;8(1):e2300292
Advanced biology 2024 Jan;8(1):e2300292
Li, P HY-021068 alleviates cerebral ischemia-reperfusion injury by inhibiting NLRP1 inflammasome and restoring autophagy function in mice.
Huang Y, Han M, Shi Q, Li X, Mo J, Liu Y, Chu Z, Li W
Experimental neurology 2024 Jan;371:114583
Experimental neurology 2024 Jan;371:114583
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Huo J, Dong W, Xu J, Ma L, You C
Experimental neurology 2024 Jan;371:114577
Experimental neurology 2024 Jan;371:114577
Microglial FoxO3a deficiency ameliorates ferroptosis-induced brain injury of intracerebral haemorrhage via regulating autophagy and heme oxygenase-1.
Wang R, Liang Z, Xue X, Mei H, Ji L, Wang B, Chen W, Gao C, Yuan S, Wu T, Qi H, Hu S, Yi L, Song Y, Liao R, Chen B
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Journal of cellular and molecular medicine 2024 Jan;28(1):e18007
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17
Oncology letters 2024 Jan;27(1):17
Glycine recalibrates iron homeostasis of lens epithelial cells by blocking lysosome-dependent ferritin degradation.
Wang L, Liu J, Ma D, Zhi X, Li L, Li S, Li W, Zhao J, Qin Y
Free radical biology & medicine 2024 Jan;210:258-270
Free radical biology & medicine 2024 Jan;210:258-270
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
High glucose levels delay the senescence of stem cells from human exfoliated deciduous teeth by suppressing autophagy.
Lu J, Zhang L, Zhu N, Wang D, Xie F, Qin M, Wang Y
Archives of oral biology 2024 Jan;157:105851
Archives of oral biology 2024 Jan;157:105851
Exosomal microRNA profiling revealed enhanced autophagy suppression and anti-tumor effects of a combination of compound Phyllanthus urinaria and lenvatinib in hepatocellular carcinoma.
Liao M, Qin M, Liu L, Huang H, Chen N, Du H, Huang D, Wang P, Zhou H, Tong G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155091
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155091
Study of hispidulin in the treatment of uric acid nephropathy based on NF-κB signaling pathway.
Li X, Gu Y, Ren L, Cai Q, Qiu Y, He J, Qu W, Ji W
Chemical biology & drug design 2024 Jan;103(1):e14367
Chemical biology & drug design 2024 Jan;103(1):e14367
Drp1 regulated PINK1-dependent mitophagy protected duck follicular granulosa cells from acute heat stress injury.
Yang C, Luo P, Yang YT, Fu XL, Li BX, Shen X, Xu DN, Huang YM, Tian YB, Liu WJ
Poultry science 2024 Jan;103(1):103247
Poultry science 2024 Jan;103(1):103247
ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA.
Liu H, Han Z, Chen L, Zhang J, Zhang Z, Chen Y, Liu F, Wang K, Liu J, Sai N, Zhou X, Zhou C, Hu S, Wen Q, Ma L
JCI insight 2024 Jan 9;9(1)
JCI insight 2024 Jan 9;9(1)
Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation.
Accogli A, Shakya S, Yang T, Insinna C, Kim SY, Bell D, Butov KR, Severino M, Niceta M, Scala M, Lee HS, Yoo T, Stauffer J, Zhao H, Fiorillo C, Pedemonte M, Diana MC, Baldassari S, Zakharova V, Shcherbina A, Rodina Y, Fagerberg C, Roos LS, Wierzba J, Dobosz A, Gerard A, Potocki L, Rosenfeld JA, Lalani SR, Scott TM, Scott D, Azamian MS, Louie R, Moore HW, Champaigne NL, Hollingsworth G, Torella A, Nigro V, Ploski R, Salpietro V, Zara F, Pizzi S, Chillemi G, Ognibene M, Cooney E, Do J, Linnemann A, Larsen MJ, Specht S, Walters KJ, Choi HJ, Choi M, Tartaglia M, Youkharibache P, Chae JH, Capra V, Park SG, Westlake CJ
Nature communications 2024 Jan 8;15(1):365
Nature communications 2024 Jan 8;15(1):365
Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma.
Wang J, Ma C, Tang Z, Sun Z, Qaed E, Chi X, Wang J, Jamalat Y, Geng Z, Tang Z, Yao Q
Cancer cell international 2024 Jan 7;24(1):17
Cancer cell international 2024 Jan 7;24(1):17
Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis.
Sun P, Wang Z, Li S, Yin J, Gan Y, Liu S, Lin Z, Wang H, Fan Z, Qu Q, Hu Z, Li K, Miao Y
Cell & bioscience 2024 Jan 5;14(1):6
Cell & bioscience 2024 Jan 5;14(1):6
Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Ameliorate Aging-Induced BTB Impairment in Porcine Testes by Activating Autophagy and Inhibiting ROS/NLRP3 Inflammasomes via the AMPK/mTOR Signaling Pathway.
Zhou Y, Yan J, Qiao L, Zeng J, Cao F, Sheng X, Qi X, Long C, Liu B, Wang X, Yao H, Xiao L
Antioxidants (Basel, Switzerland) 2024 Jan 31;13(2)
Antioxidants (Basel, Switzerland) 2024 Jan 31;13(2)
Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice.
Ding Y, Liu S, Zhang M, Su M, Shao B
Translational andrology and urology 2024 Jan 31;13(1):25-41
Translational andrology and urology 2024 Jan 31;13(1):25-41
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Wang R, Zeng J, Chen L, Sun L, Wang Y, Xu J, He X
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer.
Wang J, Zheng F, Wang D, Yang Q
Cell death & disease 2024 Jan 29;15(1):97
Cell death & disease 2024 Jan 29;15(1):97
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Khan S, Wang T, Cobo ER, Liang B, Khan MA, Xu M, Qu W, Gao J, Barkema HW, Kastelic JP, Liu G, Han B
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation.
Zhang B, He Z, Guo J, Li F, Huang Z, Zheng W, Xing W, Li M, Zhu Y, Yang X
Aging 2024 Jan 26;16(2):1145-1160
Aging 2024 Jan 26;16(2):1145-1160
SMYD3 activates the TCA cycle to promote M1-M2 conversion in macrophages.
Zhu W, Liu L, Wu J, Gao R, Fu L, Yang X, Zou Y, Zhang S, Luo D
International immunopharmacology 2024 Jan 25;127:111329
International immunopharmacology 2024 Jan 25;127:111329
Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Bu KB, Kim M, Shin MK, Lee SH, Sung JS
International journal of molecular sciences 2024 Jan 22;25(2)
International journal of molecular sciences 2024 Jan 22;25(2)
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
Chen H, Yang X, Gao Y, Jiang H, Guo M, Zhou Y, Li C, Tan Y, Zhang Y, Xue W
Brain research 2024 Jan 15;1823:148683
Brain research 2024 Jan 15;1823:148683
Dictamnine Ameliorates DNFB-Induced Atopic Dermatitis Like Skin Lesions in Mice by Inhibiting M1 Macrophage Polarization and Promoting Autophagy.
Huang Y, Zhao C, Zheng G, Yuan Y, Gong L, Liu R, An J
Biological & pharmaceutical bulletin 2024 Jan 13;47(1):175-186
Biological & pharmaceutical bulletin 2024 Jan 13;47(1):175-186
Chinese herbal medicine alleviates autophagy and apoptosis in ovarian granulosa cells induced by testosterone through PI3K/AKT1/FOXO1 pathway.
Hu W, Xie N, Pan M, Zhang Q, Zhang H, Wang F, Qu F
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117025
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117025
Study on the neuroprotective effect of Zhimu-Huangbo extract on mitochondrial dysfunction in HT22 cells induced by D-galactose by promoting mitochondrial autophagy.
Xue A, Zhao D, Zhao C, Li X, Yang M, Zhao H, Zhao C, Lei X, Wu J, Zhang N
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117012
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117012
Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a.
Li P, Dou Q, Zhang D, Xiang Y, Tan L
Aging 2024 Jan 10;16(1):844-856
Aging 2024 Jan 10;16(1):844-856
Upregulated Tβ4 expression in inflammatory bowel disease impairs the intestinal mucus barrier by inhibiting autophagy in mice.
Hao M, Zhong K, Bai X, Wu S, Li L, He Y, Wang Z, Sun X, Wang Q, Guo Y, Sun Y, Wu L
Experimental cell research 2024 Jan 1;434(1):113871
Experimental cell research 2024 Jan 1;434(1):113871
Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.
Hu J, Hou W, Ma N, Zhang Y, Liu X, Wang Y, Ci X
Life sciences 2024 Jan 1;336:122352
Life sciences 2024 Jan 1;336:122352
MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca(2+) signaling pathway.
Zhu M, Yan M, Musa M, Li Y, Zhang Y, Zou X
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Ecotoxicology and environmental safety 2024 Jan 1;269:115906
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
Huang H, Yan J, Xu X, Feng Y, Liu H, Liu J, Xie M, Chen L, Xiang D, Peng W, Zeng L, Zeng Y, Chen F, Zhang S, Liu Q
Drug development research 2024 Feb;85(1):e22140
Drug development research 2024 Feb;85(1):e22140
Effects of exercise, metformin, and combination treatments on type 2 diabetic mellitus-induced muscle atrophy in db/db mice: Crosstalk between autophagy and the proteasome.
Xiang M, Yuan X, Zhang N, Zhang L, Liu Y, Liu J, Gao Y, Xu Y, Sun W, Tang Q, Zhang Y, Lu J
Journal of physiology and biochemistry 2024 Feb;80(1):235-247
Journal of physiology and biochemistry 2024 Feb;80(1):235-247
General Control Non-derepressible 2 Alleviates Cartilage Degeneration and Inhibits NLRP3 Inflammasome Activation in Osteoarthritis.
Fang L, Wang Z, Liu J, Lin Y, Hao W
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2024 Feb;72(2):95-108
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2024 Feb;72(2):95-108
Flavonoid 4,4'-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy.
Wang T, Yang C, Li Z, Li T, Zhang R, Zhao Y, Cheng T, Zong Z, Ma Y, Zhang D, Deng H
Redox biology 2024 Feb;69:103017
Redox biology 2024 Feb;69:103017
A conserved ion channel function of STING mediates noncanonical autophagy and cell death.
Xun J, Zhang Z, Lv B, Lu D, Yang H, Shang G, Tan JX
EMBO reports 2024 Feb;25(2):544-569
EMBO reports 2024 Feb;25(2):544-569
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination.
Chen B, Zhao Y, Xu S, Jiang F, Nie Y, Tang A, Zhou Q
Annals of hematology 2024 Feb;103(2):533-544
Annals of hematology 2024 Feb;103(2):533-544
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR-206/MAPK1 axis.
Cheng S, Liu Y, He B, Zhang J, Yang Y, Wang X, Li Z
Pathogens and disease 2024 Feb 7;82
Pathogens and disease 2024 Feb 7;82
PPAR γ activation in chondrocytes alleviates glucocorticoid-induced oxidative stress, mitochondrial impairment, and pyroptosis via autophagic flow enhancement.
Wu D, Shen Z, Gou Y, Yu T, Hong J, Wang Y, Ni F, Qiqige N, Lu H, Xue E
Chemico-biological interactions 2024 Feb 25;390:110877
Chemico-biological interactions 2024 Feb 25;390:110877
Ferritinophagy-mediated ferroptosis of spermatogonia is involved in busulfan-induced oligospermia in the mice.
Xu J, Zhang L, Si Y, Huang W, Liu R, Liu Z, Jiang Z, Xu F
Chemico-biological interactions 2024 Feb 25;390:110870
Chemico-biological interactions 2024 Feb 25;390:110870
Identifying CTH and MAP1LC3B as ferroptosis biomarkers for prognostic indication in gastric cancer decoding.
Qu H, Liang Y, Guo Q, Lu L, Yang Y, Xu W, Zhang Y, Qin Y
Scientific reports 2024 Feb 22;14(1):4352
Scientific reports 2024 Feb 22;14(1):4352
[Role of mitochondrial autophagy and the curative effect of rehmannia glutinosa leaves total glycoside capsules on nucleos(t)ide drug-induced renal injury].
Zhong K, Zhang MM, Zhu ZX, Liao X, Zhang BF, Cheng ML
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2024 Feb 20;32(2):125-132
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2024 Feb 20;32(2):125-132
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Zhao Y, Ding ZG, Yan YJ, Yang R, Qi MM, Pan SK, Xie JL, Sun YH, Xiang J
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1.
Wu R, Xu F, Li J, Wang F, Chen N, Wang X, Chen Q
iScience 2024 Feb 16;27(2):108982
iScience 2024 Feb 16;27(2):108982
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P
Nature communications 2024 Feb 16;15(1):1429
Nature communications 2024 Feb 16;15(1):1429
Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression.
Sun B, Lin L, Yao T, Yao J, Zhang G, Li Y, Li C
Journal of ethnopharmacology 2024 Feb 10;320:117396
Journal of ethnopharmacology 2024 Feb 10;320:117396
Honokiol inhibits human osteosarcoma MG63 cell migration by upregulating FTO and Smad6 to promote autophagy.
Wu J, Xu W, Li J, Luo C, Chen B, Lin L, Huang T, Luo T, Yang L, Yang J
Molecular and cellular probes 2024 Dec;78:101988
Molecular and cellular probes 2024 Dec;78:101988
Tanshinone IIA alleviates inflammation-induced skeletal muscle atrophy by regulating mitochondrial dysfunction.
Han D, Chen YB, Zhao K, Li HZ, Chen XY, Zhu GZ, Tu C, Gao JW, Zhuang JS, Wu ZY, Zhong ZM
Archives of biochemistry and biophysics 2024 Dec;762:110215
Archives of biochemistry and biophysics 2024 Dec;762:110215
HucMSC extracellular vesicles increasing SATB 1 to activate the Wnt/β-catenin pathway in 6-OHDA-induced Parkinson's disease model.
He Y, Li R, Yu Y, Xu Z, Gao J, Wang C, Huang C, Qi Z
IUBMB life 2024 Dec;76(12):1154-1174
IUBMB life 2024 Dec;76(12):1154-1174
Homogeneous Polyporus polysaccharide exerts anti-bladder cancer effects via autophagy induction.
Luo S, Huang X, Li S, Chen Y, Zhang X, Zeng X
Pharmaceutical biology 2024 Dec;62(1):214-221
Pharmaceutical biology 2024 Dec;62(1):214-221
FOXG1 interaction with SATB2 promotes autophagy to alleviate neuroinflammation and mechanical abnormal pain in rats with lumbar disc herniation.
Wang Z, Gu Y, Wang H, Chen Y, Chen H, Wang X, Yuan W
Annals of medicine 2024 Dec;56(1):2399967
Annals of medicine 2024 Dec;56(1):2399967
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.
Hong R, Shi Y, Fan Z, Gao Y, Chen H, Pan C
Toxicology 2024 Dec;509:153996
Toxicology 2024 Dec;509:153996
Protein arginine methyltransferase 5 confers the resistance of triple-negative breast cancer to nanoparticle albumin-bound paclitaxel by enhancing autophagy through the dimethylation of ULK1.
Kong J, Dong Y, Li M, Fan J, Wang T
Toxicology and applied pharmacology 2024 Dec;493:117145
Toxicology and applied pharmacology 2024 Dec;493:117145
Astaxanthin attenuates diabetic kidney injury through upregulation of autophagy in podocytes and pathological crosstalk with mesangial cells.
Hong M, Nie Z, Chen Z, Bao B
Renal failure 2024 Dec;46(2):2378999
Renal failure 2024 Dec;46(2):2378999
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Du Y, Wu M, Song S, Bian Y, Shi Y
Renal failure 2024 Dec;46(1):2338933
Renal failure 2024 Dec;46(1):2338933
Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway.
Liu H, Wang J, Yue G, Xu J
Renal failure 2024 Dec;46(1):2303396
Renal failure 2024 Dec;46(1):2303396
Enhancing retention and permeation of rapamycin for osteoarthritis therapy using a two-stage drug delivery system.
Lin G, Huang H, Sun M, He Z, Li S, Liang X, Yan Y, Qiu C, Li S, Zhao X, Zhu W, Kou L, Chen R
Materials today. Bio 2024 Dec;29:101279
Materials today. Bio 2024 Dec;29:101279
Linoleic Acid Enhances Renal Tubular Epithelial Cells Autophagy Caused by Calcium Oxalate Monohydrate Crystals.
Ma W, Wei W, Dong Y, Zhao Y, Xia T, Wang X, Han C
Journal of cellular and molecular medicine 2024 Dec;28(24):e70250
Journal of cellular and molecular medicine 2024 Dec;28(24):e70250
Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products.
Chen KY, Cheng CJ, Chang YT, Lin YH, Huang YH, Lin SY, Wang LC, Jhan KY, Chiu CH
International journal for parasitology. Drugs and drug resistance 2024 Dec;26:100560
International journal for parasitology. Drugs and drug resistance 2024 Dec;26:100560
TRPML1 ameliorates seizures-related neuronal injury by regulating autophagy and lysosomal biogenesis via Ca(2+)/TFEB signaling pathway.
Peng T, Xie Y, Zhao S, Wang X, Zhang W, Xie Y, Wang C, Xie N
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167477
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167477
Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.
Tao L, Liu Z, Li X, Wang H, Wang Y, Zhou D, Zhang H
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167459
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167459
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Gnetupendin A protects against ischemic stroke through activating the PI3K/AKT/mTOR-dependent autophagy pathway.
Mu D, Liu J, Mi Y, Wang D, Xu L, Yang Y, Liu Y, Liang D, Hou Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156233
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156233
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy.
Chen Z, Zhang M, Xu Q, Lu P, Liu M, Yin R, Liu X, Dai Y, Gao X, Gong J, Zhang S, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156187
Forsythoside A mitigates osteoarthritis and inhibits chondrocyte senescence by promoting mitophagy and suppressing NLRP3 inflammasome via the Nrf2 pathway.
Li W, Zhong Y, Lin Z, Deng Z, Long D, Li M, Li C, Mao G, Kang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156052
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156052
The Antipsychotic Drug Aripiprazole Suppresses Colorectal Cancer by Targeting LAMP2a to Induce RNH1/miR-99a/mTOR-Mediated Autophagy and Apoptosis.
Hu HF, Fu JY, Han L, Gao GB, Zhang WX, Yu SM, Li N, Li YJ, Lu YF, Ding XF, Pan YL, Wang Y, He QY
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2409498
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2409498
Aloe Emodin Alleviates Radiation-Induced Heart Disease via Blocking P4HB Lactylation and Mitigating Kynurenine Metabolic Disruption.
Ouyang F, Li Y, Wang H, Liu X, Tan X, Xie G, Zeng J, Zeng G, Luo Q, Zhou H, Chen S, Hou K, Fang J, Zhang X, Zhou L, Li Y, Gao A
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406026
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2406026
Rationally designed febuxostat-based hydroxamic acid and its pH-Responsive nanoformulation elicits anti-tumor activity.
Ritika, Liao ZY, Chen PY, Rao NV, Mathew J, Sharma R, Grewal AS, Singh G, Mehan S, Liou JP, Pan CH, Nepali K
European journal of medicinal chemistry 2024 Dec 5;279:116866
European journal of medicinal chemistry 2024 Dec 5;279:116866
CD39 inhibitor (POM-1) enhances radiosensitivity of esophageal squamous cell carcinoma (ESCC) cells by promoting apoptosis through the Bax/Bcl-2/Caspase 9/Caspase 3 pathway.
Wang Y, Zhang R, Huang X, He X, Geng S, Pan S, Guo W, Liu X, Dang Y, Qu J, Ma H, Zhao X
International immunopharmacology 2024 Dec 5;142(Pt B):113242
International immunopharmacology 2024 Dec 5;142(Pt B):113242
GDF11 promotes osteogenic/odontogenic differentiation of dental pulp stem cells to accelerate dentin restoration via modulating SIRT3/FOXO3-mediated mitophagy.
Deng M, Tang R, Xu Y, Xu Y, Chen L
International immunopharmacology 2024 Dec 5;142(Pt B):113092
International immunopharmacology 2024 Dec 5;142(Pt B):113092
Tenovin-6 exhibits inhibitory effects on the growth of Sonic Hedgehog (SHH) medulloblastoma, as evidenced by both in vitro and in vivo studies.
Wang B, Xu T, Qiu C, Yu L, Xu S, Zhao X, Xu C, Tan F, Sheng H, Zhang N
International immunopharmacology 2024 Dec 5;142(Pt A):113075
International immunopharmacology 2024 Dec 5;142(Pt A):113075
Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus.
Xiang Q, Wouters C, Chang P, Lu YN, Liu M, Wang H, Yang J, Pekosz A, Zhang Y, Wang J
bioRxiv : the preprint server for biology 2024 Dec 5;
bioRxiv : the preprint server for biology 2024 Dec 5;
Molecular Insights into the Regulation of GNPTAB by TMEM251.
Yang X, Doray B, Venkatarangan V, Jennings BC, Henn D, Liang J, Zhao H, Zhang W, Zhang B, Yu L, Chen L, Kornfeld S, Li M
bioRxiv : the preprint server for biology 2024 Dec 5;
bioRxiv : the preprint server for biology 2024 Dec 5;
Fisetin Ameliorates Hepatocyte Lipid Droplet Accumulation via Targeting the Rhythmic Protein BMAL1 to Regulate Cell Death-Inducing DNA Fragmentation Factor-α-like Effector C-Mediated Lipid Droplet Fusion.
Zhang R, Liu M, Lu J, Lu S, Wang Y, Guan S
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26884-26897
Journal of agricultural and food chemistry 2024 Dec 4;72(48):26884-26897
Interfering Nuclear Protein Laminb1 Induces DNA Damage and Reduces Vemurafenib Resistance in Melanoma Cells In Vitro.
Li Y, Feng Y, Chen D
Cancers 2024 Dec 4;16(23)
Cancers 2024 Dec 4;16(23)
Poly(allylamine)/tripolyphosphate nanocomplex coacervate as a NLRP3-dependent systemic adjuvant for vaccine development.
Rizzo GP, Sanches RC, Chavero C, Bianchi DS, Apuzzo E, Herrera SE, Agazzi ML, Cortez ML, Marmisollé WA, Keitelman IA, Trevani AS, Oliveira SC, Azzaroni O, Smaldini PL, Docena GH
bioRxiv : the preprint server for biology 2024 Dec 4;
bioRxiv : the preprint server for biology 2024 Dec 4;
Hypoxia-induced TPC2 transcription and glycosylation aggravates pulmonary arterial hypertension by blocking autophagy flux.
Li C, Li C, Jiang Y, Liu M, Yang C, Lu J, Jiang Y
Scientific reports 2024 Dec 28;14(1):31223
Scientific reports 2024 Dec 28;14(1):31223
Lactate Promotes Hypoxic Granulosa Cells' Autophagy by Activating the HIF-1α/BNIP3/Beclin-1 Signaling Axis.
Pan Y, Wu G, Chen M, Lu X, Shen M, Li H, Liu H
Genes 2024 Dec 26;16(1)
Genes 2024 Dec 26;16(1)
Quercetin inhibits mitophagy-mediated apoptosis and inflammatory response by targeting the PPARγ/PGC-1α/NF-κB axis to improve acute liver failure.
Wu H, Wu L, Luo L, Wu YT, Zhang QX, Li HY, Zhang BF
International immunopharmacology 2024 Dec 25;143(Pt 2):113444
International immunopharmacology 2024 Dec 25;143(Pt 2):113444
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Wang Y, Guo J, Zhang D, Shi C, Zhang X, Gong Z
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
Stilbene glycosides alleviate atherosclerosis partly by promoting lipophagy of dendritic cells.
Yang Y, Bai D, Jiang L, Chen Y, Wang M, Wang W, Wang H, He Q, Bu G, Long J, Yuan D
International immunopharmacology 2024 Dec 25;143(Pt 1):113223
International immunopharmacology 2024 Dec 25;143(Pt 1):113223
mTOR Inhibitor Everolimus Modulates Tumor Growth in Small-Cell Carcinoma of the Ovary, Hypercalcemic Type and Augments the Drug Sensitivity of Cancer Cells to Cisplatin.
Zheng K, Gao Y, Xu J, Kang M, Chai R, Jin G, Kang Y
Biomedicines 2024 Dec 24;13(1)
Biomedicines 2024 Dec 24;13(1)
Comparison of biocompatibility of epoxy resin and bioceramic-based root canal sealers.
Uygun AD, Şen S, Çelik S
Clinical oral investigations 2024 Dec 2;28(12):673
Clinical oral investigations 2024 Dec 2;28(12):673
2'-Hydroxycinnamaldehyde, a Natural Product from Cinnamon, Alleviates Ischemia/Reperfusion-Induced Microvascular Dysfunction and Oxidative Damage in Rats by Upregulating Cytosolic BAG3 and Nrf2/HO-1.
Cheng YH, Chiang CY, Wu CH, Chien CT
International journal of molecular sciences 2024 Dec 2;25(23)
International journal of molecular sciences 2024 Dec 2;25(23)
Visualizing ER-phagy and ER architecture in vivo.
Sang Y, Li B, Su T, Zhan H, Xiong Y, Huang Z, Wang C, Cong X, Du M, Wu Y, Yu H, Yang X, Ding K, Wang X, Miao X, Gong W, Wang L, Zhao J, Zhou Y, Liu W, Hu X, Sun Q
The Journal of cell biology 2024 Dec 2;223(12)
The Journal of cell biology 2024 Dec 2;223(12)
LOC730101 improves ovarian cancer drug sensitivity by inhibiting autophagy-mediated DNA damage repair via BECN1.
Zhong Y, Shuai Y, Yang J, Zhang M, He T, Zheng L, Yang S, Peng S
Cell death & disease 2024 Dec 18;15(12):893
Cell death & disease 2024 Dec 18;15(12):893
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway.
Qiu H, Gao L, Shi W, Wang J, Li B, Ke S, Chen J, Gong Y, Wu Y, Zhao W, Chen Y
Cancer letters 2024 Dec 16;611:217401
Cancer letters 2024 Dec 16;611:217401
Discovery of sp(3)-rich diazatricycloundecanes as lysosomotropic autophagy inhibitors.
Miura K, Doi T, Umedera K, Nakamura H
European journal of medicinal chemistry 2024 Dec 15;280:116923
European journal of medicinal chemistry 2024 Dec 15;280:116923
TFEB signaling promotes autophagic degradation of NLRP3 to attenuate neuroinflammation in diabetic encephalopathy.
Lin Y, Cheng L, Chen Y, Li W, Guo Q, Miao Y
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1481-C1496
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1481-C1496
Potential Effects of Indomethacin on Alleviating Osteoarthritis Progression in Vitro.
Zhao X, Wang T, Li N, Meng Z, Wang W, Wang B, Song D
Journal of musculoskeletal & neuronal interactions 2024 Dec 1;24(4):409-419
Journal of musculoskeletal & neuronal interactions 2024 Dec 1;24(4):409-419
Hydrogen sulfide ameliorated endothelial dysfunction in hyperhomocysteinemia rats: Mechanism of IRE1α/JNK pathway-mediated autophagy.
Gao Y, Xu J, He K, Guo Q, Xiao L, Jin S, Tian D, Teng X, An C, Xue H, Wu Y
Nitric oxide : biology and chemistry 2024 Dec 1;153:72-81
Nitric oxide : biology and chemistry 2024 Dec 1;153:72-81
The combination of Butyricicoccus pullicaecorum and 3-hydroxyanthranilic acid prevents postmenopausal osteoporosis by modulating gut microbiota and Th17/Treg.
Zhu F, Liu H, Cao Y, Dai B, Wu H, Li W
European journal of nutrition 2024 Aug;63(5):1945-1959
European journal of nutrition 2024 Aug;63(5):1945-1959
SNX14 inhibits autophagy via the PI3K/AKT/mTOR signaling cascade in breast cancer cells.
Lv S, Jiang H, Yu L, Zhang Y, Sun L, Xu J
Journal of molecular histology 2024 Aug;55(4):391-401
Journal of molecular histology 2024 Aug;55(4):391-401
USP19 Stabilizes TAK1 to Regulate High Glucose/Free Fatty Acid-induced Dysfunction in HK-2 Cells.
Yan XH, Zhu YN, Zhu YT
Current medical science 2024 Aug;44(4):707-717
Current medical science 2024 Aug;44(4):707-717
CRHR1 antagonist alleviated depression-like behavior by downregulating p62 in a rat model of post-stroke depression.
Liu H, Zhang Y, Hou X, Zhu C, Yang Q, Li K, Fan L, Zhang X, Jiang X, Jin X, Lei H, Chen T, Zhang F, Zhang Z, Song J
Experimental neurology 2024 Aug;378:114822
Experimental neurology 2024 Aug;378:114822
Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
Zhan XZ, Luo P, Zhang C, Zhang LJ, Shen X, Jiang DL, Liu WJ
Animal reproduction science 2024 Aug;267:107540
Animal reproduction science 2024 Aug;267:107540
The effect of airborne particulate matter 2.5 (PM(2.5)) on meibomian gland.
Chen X, Ren Y, Zheng T, Cheng H, Shen Y, Liu Y, Ke M
Experimental eye research 2024 Aug;245:109956
Experimental eye research 2024 Aug;245:109956
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Yue C, Lu W, Fan S, Huang Z, Yang J, Dong H, Zhang X, Shang Y, Lai W, Li D, Dong T, Yuan A, Wu J, Kang L, Hu Y
Nature nanotechnology 2024 Aug;19(8):1203-1215
Nature nanotechnology 2024 Aug;19(8):1203-1215
Dexmedetomidine facilitates autophagic flux to promote liver regeneration by suppressing GSK3β activity in mouse partial hepatectomy.
Yao X, Liu Y, Sui Y, Zheng M, Zhu L, Li Q, Irwin MG, Yang L, Zhan Q, Xiao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117038
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117038
Tanshinone I improves TNBC chemosensitivity by suppressing late-phase autophagy through AKT/p38 MAPK signaling pathway.
Tang X, Gong J, Ren L, Wang Z, Yang B, Wang W, Wang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117037
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117037
Exosomes-mediated transmission of standard bovine viral diarrhea strain OregonC24Va in bovine trophoblast cells.
Liang Y, Liu B, Xiao L, Ren S, Sheng X, Qi X, Zhang Z, Yuan N, Guo K, Wang X
Journal of reproductive immunology 2024 Aug;164:104254
Journal of reproductive immunology 2024 Aug;164:104254
Baicalein: A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement.
Liu N, Cui X, Yan W, Guo T, Wang Z, Wei X, Sun Y, Liu J, Xian C, Ma W, Chen L
Journal of pharmaceutical analysis 2024 Aug;14(8):100968
Journal of pharmaceutical analysis 2024 Aug;14(8):100968
A Lipid-Sensitive Spider Peptide Toxin Exhibits Selective Anti-Leukemia Efficacy through Multimodal Mechanisms.
Zhang P, Luo W, Zhang Z, Lv M, Sang L, Wen Y, Wang L, Ding C, Wu K, Li F, Nie Y, Zhu J, Liu X, Yi Y, Ding X, Zeng Y, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2404937
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2404937
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Zhao W, Shen T, Zhao B, Li M, Deng Z, Huo Y, Aernouts B, Loor JJ, Psifidi A, Xu C
Journal of animal science and biotechnology 2024 Aug 9;15(1):109
Journal of animal science and biotechnology 2024 Aug 9;15(1):109
Discovery, Synthesis, and Activity Evaluation of Novel Five-Membered Sulfur-Containing Heterocyclic Nucleosides as Potential Anticancer Agents In Vitro and In Vivo.
Hao EJ, Zhao Y, Yu M, Li XJ, Wang KX, Su FY, Liang YR, Wang Y, Guo HM
Journal of medicinal chemistry 2024 Aug 8;67(15):12553-12570
Journal of medicinal chemistry 2024 Aug 8;67(15):12553-12570
Antidepressant Sertraline Synergistically Enhances Paclitaxel Efficacy by Inducing Autophagy in Colorectal Cancer Cells.
He L, Tian Y, Liu Q, Bao J, Ding RB
Molecules (Basel, Switzerland) 2024 Aug 7;29(16)
Molecules (Basel, Switzerland) 2024 Aug 7;29(16)
SIGMAR1 targets AMPK/ULK1 pathway to inhibit SH-SY5Y cell apoptosis by regulating endoplasmic reticulum stress and autophagy.
Kong M, Chen Z, Lin Z, Yin P, Zhao Q
Functional & integrative genomics 2024 Aug 7;24(4):134
Functional & integrative genomics 2024 Aug 7;24(4):134
Baicalin Ameliorates Cartilage Injury in Rats With Osteoarthritis via Modulating miR-766-3p/AIFM1 Axis.
Liu J, Zhou H, Chen J, Zuo Q, Liu F
Physiological research 2024 Aug 31;73(4):633-642
Physiological research 2024 Aug 31;73(4):633-642
The effects of the atrial natriuretic peptide deficiency on renal cortical mitochondrial bioenergetics in the Dahl SS rat.
Cherezova A, Sudarikova A, Vasileva V, Iurchenko R, Nikiforova A, Spires DR, Zamaro AS, Jones AC, Schibalski RS, Dong Z, Palygin O, Stadler K, Ilatovskaya DV
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23891
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e23891
Magnoflorine attenuates Ang II-induced cardiac remodeling via promoting AMPK-regulated autophagy.
Zhu M, Hu J, Pan Y, Jiang Q, Shu C
Cardiovascular diagnosis and therapy 2024 Aug 31;14(4):576-588
Cardiovascular diagnosis and therapy 2024 Aug 31;14(4):576-588
Autophagy-enabled protein degradation: Key to platelet activation and ANGII production in patients with type 2 diabetes mellitus.
Wu Q, Yu S, Zang S, Peng K, Wang Z
Heliyon 2024 Aug 30;10(16):e36131
Heliyon 2024 Aug 30;10(16):e36131
Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy.
Knupp J, Chen YJ, Wang E, Arvan P, Tsai B
Cell reports 2024 Aug 27;43(8):114619
Cell reports 2024 Aug 27;43(8):114619
NLRP4 renders pancreatic cancer resistant to olaparib through promotion of the DNA damage response and ROS-induced autophagy.
Xiao M, Yang J, Dong M, Mao X, Pan H, Lei Y, Tong X, Yu X, Yu X, Shi S
Cell death & disease 2024 Aug 26;15(8):620
Cell death & disease 2024 Aug 26;15(8):620
The different paradigms of NK cell death in patients with severe trauma.
Chang TD, Chen D, Luo JL, Wang YM, Zhang C, Chen SY, Lin ZQ, Zhang PD, Tang TX, Li H, Dong LM, Wu N, Tang ZH
Cell death & disease 2024 Aug 21;15(8):606
Cell death & disease 2024 Aug 21;15(8):606
A positive FOXP3/lncRNA SNHG1 feedback axis ameliorates cardiomyocytes hypertrophy by negatively regulating Parkin-mediated mitophagy.
Zhang J, Luo X, Yang X, Wang B, Zheng L, Yan S
International immunopharmacology 2024 Aug 20;137:112526
International immunopharmacology 2024 Aug 20;137:112526
A quinolinyl resveratrol derivative alleviates acute ischemic stroke injury by promoting mitophagy for neuroprotection via targeting CK2α'.
Xu L, Mi Y, Meng Q, Liu Y, Wang Y, Zhang Y, Yang Y, Chen G, Liu Y, Hou Y
International immunopharmacology 2024 Aug 20;137:112524
International immunopharmacology 2024 Aug 20;137:112524
Splicing Factor PTBP1 Silencing Induces Apoptosis of Human Cervical Cancer Cells via PI3K/AKT Pathway and Autophagy.
Liu T, Zhou Y, Chen L, Liu Q, Hu D, Huang R, Ji H, Lin Y, Sun Y
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):289
Frontiers in bioscience (Landmark edition) 2024 Aug 19;29(8):289
Canagliflozin attenuates post-resuscitation myocardial dysfunction in diabetic rats by inhibiting autophagy through the PI3K/Akt/mTOR pathway.
Huang Q, Shi W, Wang M, Zhang L, Zhang Y, Hu Y, Pan S, Ling B, Zhu H, Xiao W, Hua T, Yang M
iScience 2024 Aug 16;27(8):110429
iScience 2024 Aug 16;27(8):110429
Mitochondria-Targeted Multifunctional Nanoprodrugs by Inhibiting Metabolic Reprogramming for Combating Cisplatin-Resistant Lung Cancer.
Lu H, Tong W, Jiang M, Liu H, Meng C, Wang K, Mu X
ACS nano 2024 Aug 13;18(32):21156-21170
ACS nano 2024 Aug 13;18(32):21156-21170
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.
Luo YW, Zhou JP, Ji H, Xu D, Zheng A, Wang X, Dai Z, Luo Z, Cao F, Wang XY, Bai Y, Chen D, Chen Y, Wang Q, Yang Y, Zhang X, Chiu S, Peng X, Huang AL, Tang KF
Nature communications 2024 Aug 13;15(1):6964
Nature communications 2024 Aug 13;15(1):6964
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Zhang W, Peng H, Yang D, Song G, He J, Zhou Y, Huang C, Huang B
Neuroscience letters 2024 Aug 10;837:137921
Neuroscience letters 2024 Aug 10;837:137921
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Li H, Wu D, Zhang H, Liu S, Zhen J, Yan Y, Li P
BMC gastroenterology 2024 Aug 1;24(1):245
BMC gastroenterology 2024 Aug 1;24(1):245
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
Li Y, Liu W, Zhao R, An Y, Zhang M, Ren X, He H
International dental journal 2024 Apr;74(2):284-293
International dental journal 2024 Apr;74(2):284-293
SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Apr;73(4):641-654
Crosstalk between autophagy and inflammasomes in ricin-induced inflammatory injury.
Zhang S, Zhao N, Song S, Wang Y, Wang Y, Sun C, Dong M, Huo M, Xu N, Liu W, Li G
Toxicology and applied pharmacology 2024 Apr;485:116890
Toxicology and applied pharmacology 2024 Apr;485:116890
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G
Inflammation 2024 Apr;47(2):718-732
Inflammation 2024 Apr;47(2):718-732
Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.
Zuo Z, Li Q, Zhou S, Yu R, Wu C, Chen J, Xiao Y, Chen H, Song J, Pan Y, Wang W
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780
Ataxin-2 sequesters Raptor into aggregates and impairs cellular mTORC1 signaling.
Liu YJ, Wang JY, Zhang XL, Jiang LL, Hu HY
The FEBS journal 2024 Apr;291(8):1795-1812
The FEBS journal 2024 Apr;291(8):1795-1812
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
Programmed cell death 4 blocks autophagy and promotes dopaminergic neuronal injury in Parkinson's disease.
Cao G, Kang T, Li N, Li P
Experimental and therapeutic medicine 2024 Apr;27(4):135
Experimental and therapeutic medicine 2024 Apr;27(4):135
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
Tumor cell-derived LC3B(+)extracellular vesicles mediate the crosstalk between tumor microenvironment and immunotherapy efficacy in hepatocellular carcinoma via the HSP90α-IL-6/IL-8 signaling axis.
Chen YQ, Man ZS, Zheng L, Zhang Y, Zhao CW, Ma YT, Zhou J, Wang P, Yu Y, Gu F, Niu GP
Clinical immunology (Orlando, Fla.) 2024 Apr;261:109925
Clinical immunology (Orlando, Fla.) 2024 Apr;261:109925
Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis.
Zhu Y, Fujimaki M, Snape L, Lopez A, Fleming A, Rubinsztein DC
Nature cell biology 2024 Apr;26(4):542-551
Nature cell biology 2024 Apr;26(4):542-551
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Liu H, Zhou L, Wang X, Zheng Q, Zhan F, Zhou L, Dong Y, Xiong Y, Yi P, Xu G, Hua F
Biochemical pharmacology 2024 Apr;222:116050
Biochemical pharmacology 2024 Apr;222:116050
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Chen L, Zhao Z, Diarimalala RO, Chen Z, Wang Y, Zhan T, Zhao Y, Ma C, Wang X, Zhao C, Xiao Z, Hu K, Wu P
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.
Zhang R, Guan S, Meng Z, Zhang D, Lu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114522
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114522
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.
Li J, Qin X, Xu W, Zhang H, Huang S, Yang Y, Qin M, Mi Z, Zhong X
The international journal of biochemistry & cell biology 2024 Apr;169:106549
The international journal of biochemistry & cell biology 2024 Apr;169:106549
TFEB regulates the odontoblastic differentiation of dental pulp stem cells by promoting a positive feedback loop between mitophagy and glycolysis.
Li Y, Yang E, Geng Y, Li M, Wang X, Zhang D
Archives of oral biology 2024 Apr;160:105909
Archives of oral biology 2024 Apr;160:105909
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.
Ding X, Cao S, Wang Q, Du B, Lu K, Qi S, Cheng Y, Tuo QZ, Liang W, Lei P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2306399
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2306399
CCCP inhibits DPV infection in DEF cells by attenuating DPV manipulated ROS, apoptosis, and mitochondrial stability.
He S, Tian B, Cao H, Wang M, Cai D, Wu Y, Yang Q, Ou X, Sun D, Zhang S, Mao S, Zhao X, Huang J, Zhu D, Jia R, Chen S, Liu M, Cheng A
Poultry science 2024 Apr;103(4):103446
Poultry science 2024 Apr;103(4):103446
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Chen Y, Yuan C, Qin W, Yu B, Wei D, Wu P
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells.
Wang B, Gao M, Yao Y, Shen H, Li H, Sun J, Wang L, Zhang X
Reproductive biology and endocrinology : RB&E 2024 Apr 4;22(1):37
Reproductive biology and endocrinology : RB&E 2024 Apr 4;22(1):37
PINK1/Park2-Mediated Mitophagy Relieve Non-Alcoholic Fatty Liver Disease.
He H, Tang Y, Zhuang L, Zheng Y, Huang X
Physiological research 2024 Apr 30;73(2):253-263
Physiological research 2024 Apr 30;73(2):253-263
Targeting PARP14 with lomitapide suppresses drug resistance through the activation of DRP1-induced mitophagy in multiple myeloma.
Zhang H, Wang H, Hu Y, Gao Y, Chen J, Meng Y, Qiu Y, Hu R, Liao P, Li M, He Y, Liang Z, Xie X, Li Y
Cancer letters 2024 Apr 28;588:216802
Cancer letters 2024 Apr 28;588:216802
Abrogating PDK4 activates autophagy-dependent ferroptosis in breast cancer via ASK1/JNK pathway.
Shi W, Wang J, Chen J, Jin X, Wang Y, Yang L
Journal of cancer research and clinical oncology 2024 Apr 27;150(4):218
Journal of cancer research and clinical oncology 2024 Apr 27;150(4):218
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Deng D, Wang M, Su Y, Fang H, Chen Y, Su Z
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Magnolol promotes the autophagy of esophageal carcinoma cells by upregulating HACE1 gene expression.
Huang K, Zhang B, Feng Y, Ma H
Acta biochimica et biophysica Sinica 2024 Apr 25;56(7):1044-1054
Acta biochimica et biophysica Sinica 2024 Apr 25;56(7):1044-1054
miR-29b-1-5p exacerbates myocardial injury induced by sepsis in a mouse model by targeting TERF2.
Jiang Y, Xu J, Zeng H, Lin Z, Yi Q, Guo J, Xiao F
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):607-620
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):607-620
Network pharmacology, molecular docking, and in vitro experimental verification of the mechanism of Guanxining in treating diabetic atherosclerosis.
Wang W, Wang S, Li Y, Zhu M, Xu Q, Luo B, Liu Y, Liu Y
Journal of ethnopharmacology 2024 Apr 24;324:117792
Journal of ethnopharmacology 2024 Apr 24;324:117792
m(1)A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma.
Wu Y, Li L, Wang L, Zhang S, Zeng Z, Lu J, Wang Z, Zhang Y, Zhang S, Li H, Chen T
BMC cancer 2024 Apr 22;24(1):506
BMC cancer 2024 Apr 22;24(1):506
Chrysin Inhibits TAMs-Mediated Autophagy Activation via CDK1/ULK1 Pathway and Reverses TAMs-Mediated Growth-Promoting Effects in Non-Small Cell Lung Cancer.
Tang X, Luo X, Wang X, Zhang Y, Xie J, Niu X, Lu X, Deng X, Xu Z, Wu F
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Pharmaceuticals (Basel, Switzerland) 2024 Apr 17;17(4)
Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.
Zhang W, Chen L, Liu J, Chen B, Shi H, Chen H, Qi H, Wu Z, Mao X, Wang X, Huang Y, Li J, Yu Z, Zhong M, Wang T, Li Q
Journal of experimental & clinical cancer research : CR 2024 Apr 16;43(1):114
Journal of experimental & clinical cancer research : CR 2024 Apr 16;43(1):114
Tetrandrine alleviates pulmonary fibrosis by inhibiting alveolar epithelial cell senescence through PINK1/Parkin-mediated mitophagy.
Chu L, Zhuo J, Huang H, Chen W, Zhong W, Zhang J, Meng X, Zou F, Cai S, Zou M, Dong H
European journal of pharmacology 2024 Apr 15;969:176459
European journal of pharmacology 2024 Apr 15;969:176459
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Cheng PP, Yu F, Chen SJ, Feng X, Jia ZH, Hu SH, Cui XL, Zhou YY, Niu Q, Liang LM, Wang M, Song LJ, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents.
Wang Y, Gu L, Li J, Wang R, Zhuang Y, Li X, Wang X, Zhang J, Liu Q, Wang J, Song SJ
European journal of medicinal chemistry 2024 Apr 15;270:116312
European journal of medicinal chemistry 2024 Apr 15;270:116312
Icaritin with autophagy/mitophagy inhibitors synergistically enhances anticancer efficacy and apoptotic effects through PINK1/Parkin-mediated mitophagy in hepatocellular carcinoma.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, Chen Y, Yuan H, Chen J, Wong YK, Huang J, Gong Z, Du Q, Xiao W, Wang J
Cancer letters 2024 Apr 10;587:216621
Cancer letters 2024 Apr 10;587:216621
Cross-talk between Vimentin and autophagy regulates blood-testis barrier disruption induced by cadmium.
Chen N, Wan X, Wang M, Li Y, Wang X, Zeng L, Zhou J, Zhang Y, Cheng S, Shen Y
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123625
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123625
Luteolin and Exercise Combination Therapy Ameliorates Amyloid-β1-42 Oligomers-Induced Cognitive Impairment in AD Mice by Mediating Neuroinflammation and Autophagy.
Tao X, Zhang R, Wang L, Li X, Gong W
Journal of Alzheimer's disease : JAD 2023;92(1):195-208
Journal of Alzheimer's disease : JAD 2023;92(1):195-208
Bone marrow-derived mesenchymal stem cell-conditioned medium ameliorates diabetic foot ulcers in rats.
Xu YF, Wu YX, Wang HM, Gao CH, Xu YY, Yan Y
Clinics (Sao Paulo, Brazil) 2023;78:100181
Clinics (Sao Paulo, Brazil) 2023;78:100181
Rapamycin attenuates pyroptosis by suppressing mTOR phosphorylation and promoting autophagy in LPS-induced bronchopulmonary dysplasia.
Zhang F, Wang M, Li Z, Deng J, Fan Y, Gou Z, Zhou Y, Huang L, Lu L
Experimental lung research 2023;49(1):178-192
Experimental lung research 2023;49(1):178-192
Effects of perfluorooctane sulfonate (PFOS) on cognitive behavior and autophagy of male mice.
Zhou A, Wang L, Pi X, Fan C, Chen W, Wang Z, Rong S, Wang T
The Journal of toxicological sciences 2023;48(9):513-526
The Journal of toxicological sciences 2023;48(9):513-526
Lidocaine induces neurotoxicity in spinal cord neurons in Goto-Kakizaki rats via AMPK-mediated mitophagy.
Chen L, Fan C, Zhang X, Chen S, Ye L, Zheng X
The Journal of toxicological sciences 2023;48(11):585-595
The Journal of toxicological sciences 2023;48(11):585-595
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Mao X, Xie X, Ma J, Wei Y, Huang Z, Wang T, Zhu J, Wang Y, Zhao H, Hua J
Biological & pharmaceutical bulletin 2023;46(7):929-938
Biological & pharmaceutical bulletin 2023;46(7):929-938
LAMC2 regulates proliferation, migration, and invasion mediated by the Pl3K/AKT/mTOR pathway in oral.
Shan F, Liang L, Feng C, Xu H, Wang Z, Liu W, Pu L, Chen Z, Chen G, Wang X
Oncology research 2023;31(4):481-493
Oncology research 2023;31(4):481-493
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Liang HY, Peng F, Pan MJ, Liao SL, Wei C, Wei GY, Xie X, Xue KY, Chen MK, Yang JK, Guo WB, Liu CD, Zhou QZ
Asian journal of andrology 2023;25(4):474-483
Asian journal of andrology 2023;25(4):474-483
Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction.
Yang Q, Nie Z, Zhu Y, Hao M, Liu S, Ding X, Wang F, Wang F, Geng X
Oxidative medicine and cellular longevity 2023;2023:6897268
Oxidative medicine and cellular longevity 2023;2023:6897268
Silencing USP19 alleviates cigarette smoke extract-induced mitochondrial dysfunction in BEAS-2B cells by targeting FUNDC1.
You Y, Wang H, Wang Q, Yu Z, Zhao Z, Zhuang L, Zeng S, Zheng J, Wen W
Open medicine (Warsaw, Poland) 2023;18(1):20230798
Open medicine (Warsaw, Poland) 2023;18(1):20230798
Molecular mechanism by which the Notch signaling pathway regulates autophagy in a rat model of pulmonary fibrosis in pigeon breeder's lung.
Li Y, Lian Z, Li Q, Ding W, Wang W, Zhang L, Muhataer X, Zhou Y, Yang X, Wu C
Open medicine (Warsaw, Poland) 2023;18(1):20230629
Open medicine (Warsaw, Poland) 2023;18(1):20230629
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Zhu X, Wang S, Cheng Y, Gu H, Zhang X, Teng M, Zhang Y, Wang J, Hua W, Lu X
Frontiers in neuroscience 2023;17:1174455
Frontiers in neuroscience 2023;17:1174455
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Zheng Z, Xie J, Ma L, Hao Z, Zhang W, Li L
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling.
Wang Y, He Q, Rong K, Zhu M, Zhao X, Zheng P, Mi Y
Frontiers in pharmacology 2023;14:1338260
Frontiers in pharmacology 2023;14:1338260
Identification of autophagy-related genes in osteoarthritis articular cartilage and their roles in immune infiltration.
Qin J, Zhang J, Wu JJ, Ru X, Zhong QL, Zhao JM, Lan NH
Frontiers in immunology 2023;14:1263988
Frontiers in immunology 2023;14:1263988
Exercise prevents fatal stress-induced myocardial injury in obese mice.
Dun Y, Hu Z, You B, Du Y, Zeng L, Zhao Y, Liu Y, Wu S, Cui N, Yang F, Liu S
Frontiers in endocrinology 2023;14:1223423
Frontiers in endocrinology 2023;14:1223423
A high-concentrate diet induces inflammatory injury via regulating Ca(2+)/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows.
Meng M, Li X, Wang Z, Huo R, Ma N, Chang G, Shen X
Frontiers in immunology 2023;14:1186170
Frontiers in immunology 2023;14:1186170
Exercise improved bone health in aging mice: a role of SIRT1 in regulating autophagy and osteogenic differentiation of BMSCs.
Zhu C, Ding H, Shi L, Zhang S, Tong X, Huang M, Liu L, Guan X, Zou J, Yuan Y, Chen X
Frontiers in endocrinology 2023;14:1156637
Frontiers in endocrinology 2023;14:1156637
A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth.
Saran U, Chandrasekaran B, Tyagi A, Shukla V, Singh A, Sharma AK, Damodaran C
Frontiers in pharmacology 2023;14:1150774
Frontiers in pharmacology 2023;14:1150774
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control.
Xu Y, Chen B, Yi J, Tian F, Liu Y, Ouyang Y, Yuan C, Liu B
Frontiers in pharmacology 2023;14:1137609
Frontiers in pharmacology 2023;14:1137609
Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction.
Zheng Y, Yang W, Jia Y, Ji J, Wu L, Feng J, Li Y, Cheng Z, Zhang J, Li J, Dai W, Xu X, Wu J, Zhou Y, Guo C
Frontiers in pharmacology 2023;14:1081980
Frontiers in pharmacology 2023;14:1081980
SIRT6 drives sensitivity to ferroptosis in anaplastic thyroid cancer through NCOA4-dependent autophagy.
Yang Z, Huang R, Wang Y, Guan Q, Li D, Wu Y, Liao T, Wang Y, Xiang J
American journal of cancer research 2023;13(2):464-474
American journal of cancer research 2023;13(2):464-474
FBXO5 acts as a novel prognostic biomarker for patients with cervical cancer.
Jiang S, Zheng J, Cui Z, Li Y, Wu Q, Cai X, Zheng C, Sun Y
Frontiers in cell and developmental biology 2023;11:1200197
Frontiers in cell and developmental biology 2023;11:1200197
Combined effects of EMP and RF field on emotional behavior in mice.
Qin T, Liu L, Wang X, Guo L, Lin J, Du J, Xue Y, Lai P, Jing Y, Ding G
Frontiers in public health 2023;11:1087161
Frontiers in public health 2023;11:1087161
Inhibitory Effects of Esculetin on Liver Cancer Through Triggering NCOA4 Pathway-Mediation Ferritinophagy in vivo and in vitro.
Xiu Z, Li Y, Fang J, Han J, Li S, Li Y, Yang X, Song G, Li Y, Jin N, Zhu Y, Zhu G, Sun L, Li X
Journal of hepatocellular carcinoma 2023;10:611-629
Journal of hepatocellular carcinoma 2023;10:611-629
Elevated expression of glycolytic genes as a prominent feature of early-onset preeclampsia: insights from integrative transcriptomic analysis.
He J, Yang H, Liu Z, Chen M, Ye Y, Tao Y, Li S, Fang J, Xu J, Wu X, Qi H
Frontiers in molecular biosciences 2023;10:1248771
Frontiers in molecular biosciences 2023;10:1248771
Knockdown of ZnT4 Induced Apoptosis, Inhibited Proliferation and testosterone synthesis of TM3 cells.
Li H, Li Y, Liu J, Liu X, Li Y, Wang S, Ma J
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):565-574
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):565-574
MIR663AHG as a competitive endogenous RNA regulating TGF-β-induced epithelial proliferation and epithelial-mesenchymal transition in benign prostate hyperplasia.
Tong S, Mo M, Hu X, Wu L, Chen M, Zhao C
Journal of biochemical and molecular toxicology 2023 Sep;37(9):e23391
Journal of biochemical and molecular toxicology 2023 Sep;37(9):e23391
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer.
Wen H, Qu C, Wang Z, Gao H, Liu W, Wang H, Sun H, Gu J, Yang Z, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23145
Baicalin promotes random-pattern skin flap survival by inducing autophagy via AMPK-regulated TFEB nuclear transcription.
Zhang L, Yu G, Yu Q, Wang L, Wu L, Tao Z, Ding J, Lin D
Phytotherapy research : PTR 2023 Sep;37(9):3926-3938
Phytotherapy research : PTR 2023 Sep;37(9):3926-3938
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150
Cell death and differentiation 2023 Sep;30(9):2135-2150
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
Ma Y, Wu S, Zhao F, Li H, Li Q, Zhang J, Li H, Yuan Z
Journal of cellular and molecular medicine 2023 Sep;27(18):2701-2713
Journal of cellular and molecular medicine 2023 Sep;27(18):2701-2713
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Pan-cancer integrated bioinformatic analysis of RNA polymerase subunits reveal RNA Pol I member CD3EAP regulates cell growth by modulating autophagy.
Bhandari N, Acharya D, Chatterjee A, Mandve L, Kumar P, Pratap S, Malakar P, Shukla SK
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):1986-2002
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):1986-2002
CircEPS15, as a sponge of MIR24-3p ameliorates neuronal damage in Parkinson disease through boosting PINK1-PRKN-mediated mitophagy.
Zhou Y, Liu Y, Kang Z, Yao H, Song N, Wang M, Song C, Zhang K, Ding J, Tang J, Hu G, Lu M
Autophagy 2023 Sep;19(9):2520-2537
Autophagy 2023 Sep;19(9):2520-2537
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Liu Y, Zhang H, Liu Y, Zhang S, Su P, Wang L, Li Y, Liang Y, Wang X, Zhao W, Chen B, Luo D, Zhang N, Yang Q
Autophagy 2023 Sep;19(9):2443-2463
Autophagy 2023 Sep;19(9):2443-2463
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Li Q, Yang Q, Guo P, Feng Y, Wang S, Guo J, Tang Z, Yu W, Liao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.
Wang Z, Wang XC, Chen YF, Wang CL, Chen L, Jiang MY, Liu XW, Zhang XX, Feng YZ, Xu JH
Experimental physiology 2023 Sep;108(9):1189-1202
Experimental physiology 2023 Sep;108(9):1189-1202
Spermidine alleviating oxidative stress and apoptosis by inducing autophagy of granulosa cells in Sichuan white geese.
Jiang D, Wang X, Zhou X, Wang Z, Li S, Sun Q, Jiang Y, Ji C, Ling W, An X, Kang B
Poultry science 2023 Sep;102(9):102879
Poultry science 2023 Sep;102(9):102879
Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis.
Ji B, Liu J, Yin Y, Xu H, Shen Q, Yu J
Cell death & disease 2023 Sep 9;14(9):601
Cell death & disease 2023 Sep 9;14(9):601
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M
Respiratory research 2023 Sep 6;24(1):216
Respiratory research 2023 Sep 6;24(1):216
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.
Chen M, Hu Q, Wang S, Tao L, Hu X, Shen X
European journal of pharmacology 2023 Sep 5;954:175863
European journal of pharmacology 2023 Sep 5;954:175863
Expression Profiles of Long Non-Coding RNAs in the Articular Cartilage of Rats Exposed to T-2 Toxin.
Yu F, Wang M, Luo K, Sun L, Yu S, Zuo J, Wang Y
International journal of molecular sciences 2023 Sep 5;24(18)
International journal of molecular sciences 2023 Sep 5;24(18)
Increased DNMT1 Involvement in the Activation of LO2 Cell Death Induced by Silver Nanoparticles via Promoting TFEB-Dependent Autophagy.
Chen J, Zheng D, Cai Z, Zhong B, Zhang H, Pan Z, Ling X, Han Y, Meng J, Li H, Chen X, Zhang H, Liu L
Toxics 2023 Sep 4;11(9)
Toxics 2023 Sep 4;11(9)
Hesperidin inhibits methylation and autophagy in LPS and high glucose-induced human villous trophoblasts.
Chen Q, Hu K, Shi J, Li H, Li W
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Biochemical and biophysical research communications 2023 Sep 3;671:278-285
Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia.
Chen YX, Yang H, Wang DS, Yao YT, Chen TT, Tao L, Chen Y, Shen XC
Biochemical and biophysical research communications 2023 Sep 3;671:246-254
Biochemical and biophysical research communications 2023 Sep 3;671:246-254
MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy.
Shi X, Wu W, Feng Z, Fan P, Shi R, Zhang X
Cell reports 2023 Sep 26;42(9):113045
Cell reports 2023 Sep 26;42(9):113045
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
Sheng B, Wang W, Xia D, Qu X
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway.
Wang L, Cheng F, Pan R, Cui Z, She J, Zhang Y, Yang X
International journal of molecular sciences 2023 Sep 18;24(18)
International journal of molecular sciences 2023 Sep 18;24(18)
Long-Term Exposure to Microcystin-LR Induces Gastric Toxicity by Activating the Mitogen-Activated Protein Kinase Signaling Pathway.
Liu Y, Li Y, Tan Q, Lv Y, Tang Y, Yang Y, Yao X, Yang F
Toxins 2023 Sep 18;15(9)
Toxins 2023 Sep 18;15(9)
Mitochondrial miR-12294-5p regulated copper-induced mitochondrial oxidative stress and mitochondrial quality control imbalance by targeted inhibition of CISD1 in chicken livers.
Zhong G, Li Y, Li L, Huo Y, Zhang W, Li T, Ma F, Liao J, Li Y, Zhang H, Guo J, Pan J, Yu W, Hu L, Tang Z
Journal of hazardous materials 2023 Sep 15;458:131908
Journal of hazardous materials 2023 Sep 15;458:131908
Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney.
Qiu W, Ye J, Su Y, Zhang X, Pang X, Liao J, Wang R, Zhao C, Zhang H, Hu L, Tang Z, Su R
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:121947
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:121947
Biomimetic Microenvironmental Stiffness Boosts Stemness of Pancreatic Ductal Adenocarcinoma via Augmented Autophagy.
Gong T, Wu D, Pan H, Sun Z, Yao X, Wang D, Huang Y, Li X, Guo Y, Lu Y
ACS biomaterials science & engineering 2023 Sep 11;9(9):5347-5360
ACS biomaterials science & engineering 2023 Sep 11;9(9):5347-5360
Realgar-Induced Neurotoxicity: Crosstalk Between the Autophagic Flux and the p62-NRF2 Feedback Loop Mediates p62 Accumulation to Promote Apoptosis.
Feng R, Liu J, Yang Z, Yao T, Ye P, Li X, Zhang J, Jiang H
Molecular neurobiology 2023 Oct;60(10):6001-6017
Molecular neurobiology 2023 Oct;60(10):6001-6017
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer's disease.
Guo Y, Zhang L
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
In vitro cellular & developmental biology. Animal 2023 Oct;59(9):665-673
Edaravone Dexborneol Alleviates Neuroinflammation by Reducing Neuroglial Cell Proliferation and Suppresses Neuronal Apoptosis/Autophagy in Vascular Dementia Rats.
Zhang J, Xiao Y, Liu H, Xu L, Guo X, Gao Y, Li M, Xu J, Qi Q, Lv P
Neurochemical research 2023 Oct;48(10):3113-3128
Neurochemical research 2023 Oct;48(10):3113-3128
Irisin ameliorates diabetic kidney disease by restoring autophagy in podocytes.
Lai W, Luo D, Li Y, Li Y, Wang Q, Hu Z, Ye Z, Peng H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23175
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23175
Oocytes orchestrate protein prenylation for mitochondrial function through selective inactivation of cholesterol biosynthesis in murine species.
Sang Y, Yang Q, Guo Y, Liu X, Shen D, Jiang C, Wang X, Li K, Wang H, Yang C, Ding L, Sun H, Guo X, Li C
The Journal of biological chemistry 2023 Oct;299(10):105183
The Journal of biological chemistry 2023 Oct;299(10):105183
Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.
Fletcher E, Miserlis D, Sorokolet K, Wilburn D, Bradley C, Papoutsi E, Wilkinson T, Ring A, Ferrer L, Haynatzki G, Smith RS, Bohannon WT, Koutakis P
Translational research : the journal of laboratory and clinical medicine 2023 Oct;260:17-31
Translational research : the journal of laboratory and clinical medicine 2023 Oct;260:17-31
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Khan S, Yang J, Cobo ER, Wang Y, Xu M, Wang T, Shi Y, Liu G, Han B
Microbial pathogenesis 2023 Oct;183:106270
Microbial pathogenesis 2023 Oct;183:106270
SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca(2+)-mediated autophagy.
Bu X, Zhang J, Sun H, Wang W, Ma X, Sun L
Journal of dental sciences 2023 Oct;18(4):1685-1692
Journal of dental sciences 2023 Oct;18(4):1685-1692
The adhesion G protein-coupled receptor VLGR1/ADGRV1 controls autophagy.
Linnert J, Güler BE, Krzysko J, Wolfrum U
Basic & clinical pharmacology & toxicology 2023 Oct;133(4):313-330
Basic & clinical pharmacology & toxicology 2023 Oct;133(4):313-330
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Sun X, Ye G, Li J, Shou H, Bai G, Zhang J
Clinical and translational medicine 2023 Oct;13(10):e1457
Clinical and translational medicine 2023 Oct;13(10):e1457
Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome.
Yuan W, Liu T, Wang YY, He S, Zhang F, Wang XB, Deng SH, Zhang T, Wu DM, Xu Y
International immunopharmacology 2023 Oct;123:110756
International immunopharmacology 2023 Oct;123:110756
Dexmedetomidine Preconditioning Attenuates Myocardial Ischemia/Reperfusion Injury in Rats by Suppressing Mitophagy Via Activating Α2-Adrenergic Receptor.
Chen Y, Chen H, Chen Y, Yang Z, Zhou T, Xu W
Arquivos brasileiros de cardiologia 2023 Oct;120(10):e20220750
Arquivos brasileiros de cardiologia 2023 Oct;120(10):e20220750
Quercetin ameliorates nonalcoholic fatty liver disease (NAFLD) via the promotion of AMPK-mediated hepatic mitophagy.
Cao P, Wang Y, Zhang C, Sullivan MA, Chen W, Jing X, Yu H, Li F, Wang Q, Zhou Z, Wang Q, Tian W, Qiu Z, Luo L
The Journal of nutritional biochemistry 2023 Oct;120:109414
The Journal of nutritional biochemistry 2023 Oct;120:109414
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
Ren M, Ma K, Pang X, Liu Y, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
MicroRNA-129-1-3p attenuates autophagy-dependent cell death by targeting MCU in granulosa cells of laying hens under H(2)O(2)-induced oxidative stress.
Zhu M, Yan M, Chen J, Li H, Zhang Y
Poultry science 2023 Oct;102(10):103006
Poultry science 2023 Oct;102(10):103006
SERPINB1 promotes Senecavirus A replication by degrading IKBKE and regulating the IFN pathway via autophagy.
Yan J, Gao Y, Bai J, Li J, Li M, Liu X, Jiang P
Journal of virology 2023 Oct 31;97(10):e0104523
Journal of virology 2023 Oct 31;97(10):e0104523
Green tea catechin prevents oxidative stress-regulated autophagy and apoptosis signaling, and inhibits tenderness in postmortem bovine longissimus thoracis et lumborum muscle.
Zhu X, Li A, Sun N, Han L, Yu Q
Food chemistry: X 2023 Oct 30;19:100758
Food chemistry: X 2023 Oct 30;19:100758
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Gao Y, Lu LJ, Zhang ZZ, Yang X, Du J, Wen K, Huang H, Wang XP, Sun XL
Journal of ethnopharmacology 2023 Oct 28;315:116678
Journal of ethnopharmacology 2023 Oct 28;315:116678
Therapeutic Effect of Prolyl Endopeptidase Inhibitor in High-fat Diet-induced Metabolic Dysfunction-associated Fatty Liver Disease.
Zhang JB, Li MT, Lin SZ, Cheng YQ, Fan JG, Chen YW
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1035-1049
Journal of clinical and translational hepatology 2023 Oct 28;11(5):1035-1049
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Mu X, Hu K, Wei A, Bai J, Feng L, Jiang J
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy.
Lu J, Li XQ, Chen PP, Zhang JX, Liu L, Wang GH, Liu XQ, Jiang TT, Wang MY, Liu WT, Ruan XZ, Ma KL
JCI insight 2023 Oct 23;8(20)
JCI insight 2023 Oct 23;8(20)
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
Sun Y, Zheng H, Qian L, Liu Y, Zhu D, Xu Z, Chang W, Xu J, Wang L, Sun B, Gu L, Yuan H, Lou H
JACS Au 2023 Oct 23;3(10):2749-2762
JACS Au 2023 Oct 23;3(10):2749-2762
[High homocysteine level promotes autophagy and apoptosis of mouse hippocampal HT22 cells through the Notch1/Hes1 signaling pathway].
Zhang J, He J, Mi X, Xu X, Tian Y, Yan R
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Oct 20;43(10):1796-1803
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Oct 20;43(10):1796-1803
Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR.
Liu C, Lu C, Yixi L, Hong J, Dong F, Ruan S, Hu T, Zhao X
Breast cancer research : BCR 2023 Oct 17;25(1):124
Breast cancer research : BCR 2023 Oct 17;25(1):124
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition.
Han B, Chen Y, Song C, Chen Y, Chen Y, Ferguson D, Yang Y, He A
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Biochemical and biophysical research communications 2023 Oct 15;677:63-69
Enhanced Mitophagy in Cholesteatoma Epithelial Cells.
Li QC, Wang SQ, Cao ZZ, Zhou SH
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2023 Oct 1;44(9):e688-e694
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2023 Oct 1;44(9):e688-e694
Inhibition of autophagy can promote the apoptosis of bladder cancer cells induced by SC66 through the endoplasmic reticulum stress pathway.
Wang L, Song R, Ma M, Chen Y, Jiang Y, Li J, Yang Z, Zhang L, Jing M, Wang X, Zhang M, Fan J
Chemico-biological interactions 2023 Oct 1;384:110725
Chemico-biological interactions 2023 Oct 1;384:110725
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
CL4-modified exosomes deliver lncRNA DARS-AS1 siRNA to suppress triple-negative breast cancer progression and attenuate doxorubicin resistance by inhibiting autophagy.
Liu X, Zhang G, Yu T, Liu J, Chai X, Yin D, Zhang C
International journal of biological macromolecules 2023 Oct 1;250:126147
International journal of biological macromolecules 2023 Oct 1;250:126147
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Qiu K, Xia Q, Chen H, Ye Q, Mao H, Tian M, Gan Y, Huang Q, Wang H, Duan S
Heliyon 2023 Nov;9(11):e21851
Heliyon 2023 Nov;9(11):e21851
Grape seed proanthocyanidins regulate mitophagy of endothelial cells and promote wound healing in mice through p-JNK/FOXO3a/ROS signal pathway.
Chen L, Hao L, Yanshuo C, FangFang W, Daqin C, Weidong X, Jian X, Shaodong C, Hongyu Z, Ke X
Archives of biochemistry and biophysics 2023 Nov;749:109790
Archives of biochemistry and biophysics 2023 Nov;749:109790
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines.
Chen X, Gu J, Huang J, Wen K, Zhang G, Chen Z, Wang Z
International journal of molecular medicine 2023 Nov;52(5)
International journal of molecular medicine 2023 Nov;52(5)
Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway.
Hu H, Wang Y, Dong Y, Wang L, Chen Y, Zhou Y, Sun L
Molecular biology reports 2023 Nov;50(11):8985-8993
Molecular biology reports 2023 Nov;50(11):8985-8993
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Lian N, Tong J, Zhu W, Meng Q, Jiang M, Bian M, Li Y
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Ma H, Cui J, Liu Z, Fang W, Lu S, Cao S, Zhang Y, Chen JA, Lu L, Xie Q, Wang Y, Huang Y, Li K, Tong H, Huang J, Lu W
Oncogene 2023 Nov;42(45):3331-3343
Oncogene 2023 Nov;42(45):3331-3343
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Yan Y, Yu S, Fan Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Nov;32(11):1265-1277
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Nov;32(11):1265-1277
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway.
Fang J, Zou X, Gong L, Xi J, Liu Y, Yang X, Zhang X, Gui C
Journal of cellular and molecular medicine 2023 Nov;27(22):3478-3490
Journal of cellular and molecular medicine 2023 Nov;27(22):3478-3490
circAP1M2 activates ATG9A-associated autophagy by inhibiting miR-1249-3p to promote cisplatin resistance in oral squamous cell carcinoma.
Wenhao R, Yali C, Shaoming L, Jingjing Z, Ling G, Keqian Z
Journal of cellular physiology 2023 Nov;238(11):2612-2624
Journal of cellular physiology 2023 Nov;238(11):2612-2624
Elaidic acid induced hepatocyte pyroptosis via autophagy-CTSB-NLRP3 pathway.
Lu J, Chen Z, Bu X, Chen S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114060
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114060
Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells.
Wang Q, Jiang Y, Bao G, Yao W, Yang Q, Chen S, Wang G
Veterinary research 2023 Nov 7;54(1):103
Veterinary research 2023 Nov 7;54(1):103
GCN5L1 regulates pulmonary surfactant production by modulating lamellar body biogenesis and trafficking in mouse alveolar epithelial cells.
Xu W, Ma X, Wang Q, Ye J, Wang N, Ye Z, Chen T
Cellular & molecular biology letters 2023 Nov 7;28(1):90
Cellular & molecular biology letters 2023 Nov 7;28(1):90
Matrix stiffness triggers chemoresistance through elevated autophagy in pancreatic ductal adenocarcinoma.
Pan H, Zhu S, Gong T, Wu D, Zhao Y, Yan J, Dai C, Huang Y, Yang Y, Guo Y
Biomaterials science 2023 Nov 7;11(22):7358-7372
Biomaterials science 2023 Nov 7;11(22):7358-7372
Sulforaphane ameliorated podocyte injury according to regulation of the Nrf2/PINK1 pathway for mitophagy in diabetic kidney disease.
Wang Y, Xu Y, Wang Q, Guo F, Song Y, Fan X, Shao M, Chen D, Zhang W, Qin G
European journal of pharmacology 2023 Nov 5;958:176042
European journal of pharmacology 2023 Nov 5;958:176042
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination.
Ma Q, Yu J, Liu L, Ma X, Zhang J, Zhang J, Wang X, Deng G, Wu X
Cell death discovery 2023 Nov 28;9(1):427
Cell death discovery 2023 Nov 28;9(1):427
Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway.
Yao Z, Liu N, Lin H, Zhou Y
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1329-1340
Journal of clinical and translational hepatology 2023 Nov 28;11(6):1329-1340
ACO2 deficiency increases vulnerability to Parkinson's disease via dysregulating mitochondrial function and histone acetylation-mediated transcription of autophagy genes.
Zhu J, Xu F, Lai H, Yuan H, Li XY, Hu J, Li W, Liu L, Wang C
Communications biology 2023 Nov 25;6(1):1201
Communications biology 2023 Nov 25;6(1):1201
A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma.
Fu Q, Yi B, Su Q, Huang Y, Wang L, Zhang Z
Aging 2023 Nov 22;15(22):13213-13238
Aging 2023 Nov 22;15(22):13213-13238
High-intensity interval training alleviates exhaustive exercise-induced HSP70-assisted selective autophagy in skeletal muscle.
Lu J, Zhang LM, Liu JJ, Liu YT, Lin XY, Wang XQ, Zhang Y, Tang Q, Liu L
The journal of physiological sciences : JPS 2023 Nov 21;73(1):32
The journal of physiological sciences : JPS 2023 Nov 21;73(1):32
DJ1 Ameliorates AD-like Pathology in the Hippocampus of APP/PS1 Mice.
Peng YY, Li MX, Li WJ, Xue Y, Miao YF, Wang YL, Fan XC, Tang LL, Song HL, Zhang Q, Li X
Biomedical and environmental sciences : BES 2023 Nov 20;36(11):1028-1044
Biomedical and environmental sciences : BES 2023 Nov 20;36(11):1028-1044
IL-17A promotes tumorigenesis and upregulates PD-L1 expression in non-small cell lung cancer.
Liao H, Chang X, Gao L, Ye C, Qiao Y, Xie L, Lin J, Cai S, Dong H
Journal of translational medicine 2023 Nov 17;21(1):828
Journal of translational medicine 2023 Nov 17;21(1):828
Low-dose atorvastatin protects skeletal muscle mitochondria in high-fat diet-fed mice with mitochondrial autophagy inhibition and fusion enhancement.
Zheng P, Zhang Q, Ma W, Hu R, Gu Y, Bian Z, Yang D, Chen X, Wu H
European journal of pharmacology 2023 Nov 15;959:176085
European journal of pharmacology 2023 Nov 15;959:176085
RNA m(6)A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis.
Han X, Liu L, Huang S, Xiao W, Gao Y, Zhou W, Zhang C, Zheng H, Yang L, Xie X, Liang Q, Tu Z, Yu H, Fu J, Wang L, Zhang X, Qian L, Zhou Y
Nature communications 2023 Nov 13;14(1):7328
Nature communications 2023 Nov 13;14(1):7328
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
Liu J, Zhu Q, Pan Y, Hao S, Wang Z, Cui C, Li J, Huang Y, Xia L, Xu T, Cheng J, Shen J, Xia Y
Molecular human reproduction 2023 Nov 1;29(11)
Molecular human reproduction 2023 Nov 1;29(11)
CAB39 promotes cisplatin resistance in bladder cancer via the LKB1-AMPK-LC3 pathway.
Gao D, Wang R, Gong Y, Yu X, Niu Q, Yang E, Fan G, Ma J, Chen C, Tao Y, Lu J, Wang Z
Free radical biology & medicine 2023 Nov 1;208:587-601
Free radical biology & medicine 2023 Nov 1;208:587-601
Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles.
Zhou F, Li X, Jia K, Li F, Xue X, Liu J, Qu J, Liu R
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Nov 1;190:106581
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Nov 1;190:106581
Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair.
Yi J, Luo X, Xing J, Gedanken A, Lin X, Zhang C, Qiao G
Bioengineering & translational medicine 2023 May;8(3):e10507
Bioengineering & translational medicine 2023 May;8(3):e10507
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
Ji X, Hong J, Yang W, Yao M, Wang J, Jiang G, Wang Y, Li C, Lin J, Mou H, Li C, Li S, Chen Y, Shi M, Wang W, Lu F, Wu H, Zhao X, Qi Y, Yan S
Redox biology 2023 May;61:102635
Redox biology 2023 May;61:102635
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.
Xiao Z, Li M, Zhang X, Rong X, Xu H
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Follicular fluid exosomes regulate OVGP1 secretion in yak oviduct epithelial cells via autophagy in vitro.
Wang J, Pan Y, Wang M, Xu R, Han X, Ma R, Zhao L, Zhang T, Wang Y, Zhao T, Ding T, Baloch AR, Wang L, Cui Y, Yu S
Journal of cellular physiology 2023 May;238(5):1020-1035
Journal of cellular physiology 2023 May;238(5):1020-1035
Zinc-Deficient Diet Causes Imbalance in Zinc Homeostasis and Impaired Autophagy and Impairs Semen Quality in Mice.
Sun B, Ma J, Te L, Zuo X, Liu J, Li Y, Bi J, Wang S
Biological trace element research 2023 May;201(5):2396-2406
Biological trace element research 2023 May;201(5):2396-2406
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy.
Ma Z, Bai J, Jiang C, Zhu H, Liu D, Pan M, Wang X, Pi J, Jiang P, Liu X
Autophagy 2023 May;19(5):1512-1532
Autophagy 2023 May;19(5):1512-1532
Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages.
Hu G, Yuan Z, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114333
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114333
Rosuvastatin promotes survival of random skin flaps through AMPK-mTOR pathway-induced autophagy.
Ye H, Li F, Shen Y, Wu X, Zhao L, Zhang H, Yang J, Shui X
International immunopharmacology 2023 May;118:110059
International immunopharmacology 2023 May;118:110059
Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Liu D, Dong C, Wang F, Liu W, Jin X, Qi SL, Liu L, Jin Q, Wang S, Wu J, Wang C, Yang J, Deng H, Cai Y, Yang L, Qin J, Zhang C, Yang X, Wang MS, Yu G, Xue YW, Wang Z, Ge GB, Xu Z, Chen WL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154732
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154732
Anticancer efficacy of hirsuteine against colorectal cancer by opposite modulation of wild-type and mutant p53.
Zhang Y, Guo T, Li S, Ren Z, Gao S, Lu H, Ma X, Liu D, Liu Y, Kong D, Qiu Y
Discover oncology 2023 May 31;14(1):84
Discover oncology 2023 May 31;14(1):84
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Shao D, Shen W, Miao Y, Gao Z, Pan M, Wei Q, Yan Z, Zhao X, Ma B
Journal of animal science and biotechnology 2023 May 3;14(1):61
Journal of animal science and biotechnology 2023 May 3;14(1):61
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Jiang Z, Zhang A, Wei W, Li S
Scientific reports 2023 May 24;13(1):8389
Scientific reports 2023 May 24;13(1):8389
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis.
Gao Y, Yuan Y, Wen S, Chen Y, Zhang Z, Feng Y, Jiang B, Ma S, Hu R, Fang C, Ruan X, Yuan Y, Fang X, Luo C, Meng Z, Wang X, Guo X
Oncogenesis 2023 May 15;12(1):26
Oncogenesis 2023 May 15;12(1):26
Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.
Meng Z, Gao M, Wang C, Guan S, Zhang D, Lu J
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Journal of agricultural and food chemistry 2023 May 10;71(18):7032-7045
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
Liu F, Li M
Journal of assisted reproduction and genetics 2023 Mar;40(3):491-508
Journal of assisted reproduction and genetics 2023 Mar;40(3):491-508
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Chen D, Jiang X, Zou H
Journal of orthopaedic translation 2023 Mar;39:163-176
Journal of orthopaedic translation 2023 Mar;39:163-176
Treponema pallidum membrane protein Tp47 promotes angiogenesis through ROS-induced autophagy.
Li W, Xie L, Li QL, Xu QY, Lin LR, Liu LL, Yang TC
Journal of the European Academy of Dermatology and Venereology : JEADV 2023 Mar;37(3):558-572
Journal of the European Academy of Dermatology and Venereology : JEADV 2023 Mar;37(3):558-572
Inhibition of PI3K/Akt/mTOR signaling by NDRG2 contributes to neuronal apoptosis and autophagy in ischemic stroke.
Wang Y, Wang B, Liu Y, Guo Y, Lu H, Liu X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Mar;32(3):106984
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Mar;32(3):106984
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Zheng Y, Dai H, Chen R, Zhong Y, Zhou C, Wang Y, Zhan C, Luo J
Journal of cellular physiology 2023 Mar;238(3):582-596
Journal of cellular physiology 2023 Mar;238(3):582-596
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
Diao F, Jiang C, Sun Y, Gao Y, Bai J, Nauwynck H, Wang X, Yang Y, Jiang P, Liu X
PLoS pathogens 2023 Mar;19(3):e1011295
PLoS pathogens 2023 Mar;19(3):e1011295
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy.
Peng X, Luo R, Ran X, Guo Y, Yao YG, Qiu M
Bioorganic chemistry 2023 Mar;132:106375
Bioorganic chemistry 2023 Mar;132:106375
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Zhang P, Lei X, Ou L, Cheng Y, Miao Q, Li C, Chen Y
International immunopharmacology 2023 Mar;116:109814
International immunopharmacology 2023 Mar;116:109814
Subacute ruminal acidosis downregulates FOXA2, changes oxidative status, and induces autophagy in the livers of dairy cows fed a high-concentrate diet.
Zhang H, Xue Y, Xie W, Wang Y, Ma N, Chang G, Shen X
Journal of dairy science 2023 Mar;106(3):2007-2018
Journal of dairy science 2023 Mar;106(3):2007-2018
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Zhang M, Li L, Li S, Liu Z, Zhang N, Sun B, Wang Z, Jia D, Liu M, Wang Q
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Journal of medicinal chemistry 2023 Mar 9;66(5):3393-3410
Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
Yuan G, Xu Y, Bai X, Wang W, Wu X, Chen J, Li J, Jia X, Gu Z, Zhang X, Hu W, Wang J, Liu Y, Zhu XM
ACS applied materials & interfaces 2023 Mar 8;15(9):11431-11443
ACS applied materials & interfaces 2023 Mar 8;15(9):11431-11443
A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis.
Chen J, Feng D, Lu Y, Zhang Y, Jiang H, Yuan M, Xu Y, Zou J, Zhu Y, Zhang J, Ge C, Wang Y
Cancers 2023 Mar 5;15(5)
Cancers 2023 Mar 5;15(5)
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Xing J, Qiao G, Luo X, Liu S, Chen S, Ye G, Zhang C, Yi J
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468
Clinical science (London, England : 1979) 2023 Mar 31;137(6):453-468
PSMD2 contributes to the progression of esophageal squamous cell carcinoma by repressing autophagy.
Liu Y, Wu M, Xu S, Niu X, Liu W, Miao C, Lin A, Xu Y, Yu L
Cell & bioscience 2023 Mar 30;13(1):67
Cell & bioscience 2023 Mar 30;13(1):67
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Chen J, Lei C, Zhang H, Huang X, Yang Y, Liu J, Jia Y, Shi H, Zhang Y, Zhang J, Du J
BMC molecular and cell biology 2023 Mar 3;24(1):7
BMC molecular and cell biology 2023 Mar 3;24(1):7
Collateral activity of the CRISPR/RfxCas13d system in human cells.
Shi P, Murphy MR, Aparicio AO, Kesner JS, Fang Z, Chen Z, Trehan A, Guo Y, Wu X
Communications biology 2023 Mar 28;6(1):334
Communications biology 2023 Mar 28;6(1):334
The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.
Wang G, Lei J, Wang Y, Yu J, He Y, Zhao W, Hu Z, Xu Z, Jin Y, Gu Y, Guo X, Yang B, Gao Z, Wang Z
Cerebral cortex (New York, N.Y. : 1991) 2023 Mar 21;33(7):3866-3881
Cerebral cortex (New York, N.Y. : 1991) 2023 Mar 21;33(7):3866-3881
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Pei X, Liu D, Li J, Li L, Ding X, Zhang W, Li Z, Xu G, Li C, Li D
The Science of the total environment 2023 Mar 20;865:161242
The Science of the total environment 2023 Mar 20;865:161242
Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway.
Jiang L, Moqbel SAA, Zhu J, Fu Q, Lai J, Lin C, Wu L
Journal of orthopaedic surgery and research 2023 Mar 2;18(1):153
Journal of orthopaedic surgery and research 2023 Mar 2;18(1):153
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells.
Zhang JX, Bao SC, Chen J, Chen T, Wei HL, Zhou XY, Li JT, Yan SG
World journal of gastrointestinal oncology 2023 Mar 15;15(3):464-489
World journal of gastrointestinal oncology 2023 Mar 15;15(3):464-489
Hypothermic Oxygenated Machine Perfusion Promotes Mitophagy Flux against Hypoxia-Ischemic Injury in Rat DCD Liver.
Luo J, Hu Y, Qiao Y, Li H, Huang J, Xu K, Jiang L, Wu H, Hu X, Jia J, Zhou L, Xie H, Li J, Zheng S
International journal of molecular sciences 2023 Mar 11;24(6)
International journal of molecular sciences 2023 Mar 11;24(6)
Electroacupuncture repairs intestinal barrier by upregulating CB1 through gut microbiota in DSS-induced acute colitis.
Yang J, Wang L, Mei M, Guo J, Yang X, Liu S
Chinese medicine 2023 Mar 10;18(1):24
Chinese medicine 2023 Mar 10;18(1):24
Pre-ischaemic Treatment with Enriched Environment Alleviates Acute Neuronal Injury by Inhibiting Endoplasmic Reticulum Stress-dependent Autophagy and Apoptosis.
Han Y, Shen XY, Gao ZK, Ping Han P, Bi X
Neuroscience 2023 Mar 1;513:14-27
Neuroscience 2023 Mar 1;513:14-27
m(6)A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
Zheng R, Yu Y, Lv L, Zhang Y, Deng H, Li J, Zhang B
Experimental cell research 2023 Mar 1;424(1):113487
Experimental cell research 2023 Mar 1;424(1):113487
Role of histone deacetylase 9 in human periodontal ligament stem cells autophagy in a tumour necrosis factor α-induced inflammatory environment.
Ge W, Luo S, Zhang K, Liu L, Zhou Z, Liu Y
Tissue & cell 2023 Jun;82:102113
Tissue & cell 2023 Jun;82:102113
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury via inhibiting autophagy through PI3K/Akt/mTOR pathway.
Li J, Wang K, Liu M, He J, Zhang H, Liu H
Journal of molecular histology 2023 Jun;54(3):173-181
Journal of molecular histology 2023 Jun;54(3):173-181
Ursolic acid nanoparticles for glioblastoma therapy.
Li Y, Zhao L, Zhao Q, Zhou Y, Zhou L, Song P, Liu B, Chen Q, Deng G
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Nanomedicine : nanotechnology, biology, and medicine 2023 Jun;50:102684
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Wei Y, Sun L, Liu C, Li L
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Naunyn-Schmiedeberg's archives of pharmacology 2023 Jun;396(6):1155-1169
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2023 Jun;39(3):729-749
Cell biology and toxicology 2023 Jun;39(3):729-749
Protective Effect and Mechanism of Kuntai Capsule on Angiotensin II -Induced Hypertension in Ovariectomized Rats.
Ge XF, Li SS, Liu YH, Lu MQ, Su HN, Yang X, Sun XW
Chinese journal of integrative medicine 2023 Jun;29(6):526-533
Chinese journal of integrative medicine 2023 Jun;29(6):526-533
Robo2 promotes osteoblast differentiation and mineralization through autophagy and is activated by parathyroid hormone induction.
Yuan N, Wang X, He M
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Jun;248:152070
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2023 Jun;248:152070
Immunostimulation with chemotherapy of a ruthenium-arene complex via blockading CD47 signal in chronic myelogenous leukemia cells.
Hu G, Lv M, Guo B, Huang Y, Su Z, Qian Y, Xue X, Liu HK
Journal of inorganic biochemistry 2023 Jun;243:112195
Journal of inorganic biochemistry 2023 Jun;243:112195
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Sun H, Xu J, Wang Y, Shen S, Xu X, Zhang L, Jiang Q
Bioactive materials 2023 Jun;24:477-496
Bioactive materials 2023 Jun;24:477-496
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Wang P, Zheng SY, Jiang RL, Wu HD, Li YA, Lu JL, Xiong Y, Han B, Lin L
Free radical biology & medicine 2023 Jun;202:76-96
Free radical biology & medicine 2023 Jun;202:76-96
TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection.
Wang J, Qin X, Huang Y, Zhang Q, Pei J, Wang Y, Goren I, Ma S, Song Z, Liu Y, Xing H, Wang H, Yang B
Autophagy 2023 Jun;19(6):1844-1862
Autophagy 2023 Jun;19(6):1844-1862
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma.
Niu J, Yan T, Guo W, Wang W, Ren T, Huang Y, Zhao Z, Yu Y, Chen C, Huang Q, Lou J, Guo L
Autophagy 2023 Jun;19(6):1693-1710
Autophagy 2023 Jun;19(6):1693-1710
Tailor-Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy.
Long X, Wang H, Yan J, Li Y, Dong X, Tian S, Sun Y, Luo K, He B, Liang Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Jun;19(24):e2207898
Small (Weinheim an der Bergstrasse, Germany) 2023 Jun;19(24):e2207898
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Zheng H, Hu C, Quan Y, Ye X, Shi X, Guo Z, Wang X
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Dalton transactions (Cambridge, England : 2003) 2023 Jun 6;52(22):7626-7634
Time-dependent effect of REV-ERBα agonist SR9009 on nonalcoholic steatohepatitis and gut microbiota in mice.
Ni Y, Nan S, Zheng L, Zhang L, Zhao Y, Fu Z
Chronobiology international 2023 Jun 3;40(6):769-782
Chronobiology international 2023 Jun 3;40(6):769-782
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
Wang C, Liu T, Wang J, Cheng C, Zhang Z, Zhang J, Huang H, Li Y
Discover oncology 2023 Jun 3;14(1):86
Discover oncology 2023 Jun 3;14(1):86
ATB(0,+)-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Chen Z, Chen H, Huang L, Duan B, Dai S, Cai W, Sun M, Jiang Z, Lu R, Jiang Y, Jiang X, Zheng H, Yao Q, Kim K, Lin G, Xie C, Chu M, Chen R, Kou L
International journal of pharmaceutics 2023 Jun 25;641:123082
International journal of pharmaceutics 2023 Jun 25;641:123082
Scalp acupuncture alleviates cerebral ischemic stroke-induced motor dysfunction in rats via regulating endoplasmic reticulum stress and ER-phagy.
Zhang Y, Lou H, Lu J, Tang X, Pang T, Lei S, Cong D, Wang Y, Sun L
Scientific reports 2023 Jun 21;13(1):10119
Scientific reports 2023 Jun 21;13(1):10119
Microcystin-LR-Exposure-Induced Kidney Damage by Inhibiting MKK6-Mediated Mitophagy in Mice.
Yao X, Liu Y, Yang Y, Li Y, Hu N, Song F, Yang F
Toxins 2023 Jun 19;15(6)
Toxins 2023 Jun 19;15(6)
Mannose-Binding Lectin Reduces Oxidized Low-Density Lipoprotein Induced Vascular Endothelial Cells Injury by Inhibiting LOX1-ox-LDL Binding and Modulating Autophagy.
Zhou X, Chen X, Zhang L, Yuan J, Lin H, Zhu M, Xu X, Dong G, Fu J, Wu W
Biomedicines 2023 Jun 17;11(6)
Biomedicines 2023 Jun 17;11(6)
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Long-term effect of PBDE-99 prenatal exposure on spermatogenic injuries via the dysregulation of autophagy.
Wu J, Deng F, Tang X, Chen W, Zhou R, Zhao T, Mao X, Shu F
Journal of hazardous materials 2023 Jun 15;452:131234
Journal of hazardous materials 2023 Jun 15;452:131234
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
Feng C, Liu Y, Zhang BY, Zhang H, Shan FY, Li TQ, Zhao ZN, Wang XX, Zhang XY
ACS omega 2023 Jun 13;8(23):20739-20754
ACS omega 2023 Jun 13;8(23):20739-20754
Bioengineered Nanospores Selectively Blocking LC3-Associated Phagocytosis in Tumor-Associated Macrophages Potentiate Antitumor Immunity.
Shang Y, Lu H, Liao L, Li S, Xiong H, Yao J
ACS nano 2023 Jun 13;17(11):10872-10887
ACS nano 2023 Jun 13;17(11):10872-10887
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Li H, Wei Y, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Hao J
Acta cardiologica 2023 Jul;78(5):594-606
Acta cardiologica 2023 Jul;78(5):594-606
High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs.
Zheng P, Ma W, Gu Y, Wu H, Bian Z, Liu N, Yang D, Chen X
Journal of clinical biochemistry and nutrition 2023 Jul;73(1):61-76
Journal of clinical biochemistry and nutrition 2023 Jul;73(1):61-76
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Ruan Z, Chi J, Kong Y, Li C, Ruan X, Zhou X, Chen Y, Li Y, Luo Z
Advanced biology 2023 Jul;7(7):e2200336
Advanced biology 2023 Jul;7(7):e2200336
Analgesic Effect of Perineural Injection of BoNT/A on Neuropathic Pain Induced by Chronic Constriction Injury of Sciatic Nerve in Rats.
He JJ, Wei XM, Wu ML, Song ZB, Jiang L, Zhang WX
Neurochemical research 2023 Jul;48(7):2161-2174
Neurochemical research 2023 Jul;48(7):2161-2174
Bavachin protects against diet-induced hepatic steatosis and obesity in mice.
Wei X, Lin L, Yuan QQ, Wang XY, Zhang Q, Zhang XM, Tang KC, Guo MY, Dong TY, Han W, Huang DK, Qi YL, Zhang M, Zhang HB
Acta pharmacologica Sinica 2023 Jul;44(7):1416-1428
Acta pharmacologica Sinica 2023 Jul;44(7):1416-1428
HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.
Yin L, Zhang Q, Xie S, Cheng Z, Li R, Zhu H, Yu Q, Yuan H, Wang C, Peng H, Zhang G
Human cell 2023 Jul;36(4):1564-1577
Human cell 2023 Jul;36(4):1564-1577
NKAP acts with HDAC3 to prevent R-loop associated genome instability.
Zhang X, Duan J, Li Y, Jin X, Wu C, Yang X, Lu W, Ge W
Cell death and differentiation 2023 Jul;30(7):1811-1828
Cell death and differentiation 2023 Jul;30(7):1811-1828
The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death.
Zhang LC, Liu YN, La XQ, Li ST, Wen LN, Liu T, Li HQ, Li AP, Wu H, Wu CX, Li ZY
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113855
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113855
Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.
Xu Y, Xie Y, Wu Z, Wang H, Chen Z, Wang J, Bao W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113803
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113803
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Li D, Li Z, Dong L, Zhang Y, Lu Y, Wang J, Sun H, Wang S
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Ding M, Zhou F, Li Y, Liu C, Gu Y, Wu J, Fan G, Li Y, Li X
Chinese herbal medicines 2023 Jul;15(3):421-429
Chinese herbal medicines 2023 Jul;15(3):421-429
GPRC5B protects osteoarthritis by regulation of autophagy signaling.
He L, Xu Z, Niu X, Li R, Wang F, You Y, Gao J, Zhao L, Shah KM, Fan J, Liu M, Luo J
Acta pharmaceutica Sinica. B 2023 Jul;13(7):2976-2989
Acta pharmaceutica Sinica. B 2023 Jul;13(7):2976-2989
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
Wang X, Xu F, Kou H, Zheng Y, Yang J, Xu Z, Fang Y, Sun W, Zhu S, Jiang Q, Wei X, Xu Y
Journal of extracellular vesicles 2023 Jul;12(7):e12342
Journal of extracellular vesicles 2023 Jul;12(7):e12342
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
Gou Q, Che S, Chen M, Chen H, Shi J, Hou Y
Cancer science 2023 Jul;114(7):2871-2881
Cancer science 2023 Jul;114(7):2871-2881
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
Jia X, Qian J, Chen H, Liu Q, Hussain S, Jin J, Shi J, Hou Y
European journal of pharmacology 2023 Jul 5;950:175749
European journal of pharmacology 2023 Jul 5;950:175749
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
Astragaloside IV Blunts Epithelial-Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy.
Li D, Liu Y, Zhan Q, Zeng Y, Peng Z, He Q, Tan Q, Cao W, Wang S, Wang J
Cells 2023 Jul 4;12(13)
Cells 2023 Jul 4;12(13)
New fungal protein from Pleurotus ferulae lanzi induces AMPK-mediated autophagy and G1-phase cell cycle arrest in A549 lung cancer cells.
Liu MH, Liu F, Ng TB, Liu ZK
International journal of biological macromolecules 2023 Jul 31;244:125453
International journal of biological macromolecules 2023 Jul 31;244:125453
PTEN Overexpression Alters Autophagy Levels and Slows Sodium Arsenite-Induced Hepatic Stellate Cell Fibrosis.
Huang F, Ding G, Yuan Y, Zhao L, Ding W, Wu S
Toxics 2023 Jul 3;11(7)
Toxics 2023 Jul 3;11(7)
Cold exposure protects against medial arterial calcification development via autophagy.
Li FX, Liu JJ, Xu F, Shan SK, Zheng MH, Lei LM, Lin X, Guo B, Li CC, Wu F, Tang KX, Cao YC, Wu YY, Duan JY, Wu YL, He SY, Chen X, Yuan LQ
Journal of nanobiotechnology 2023 Jul 17;21(1):226
Journal of nanobiotechnology 2023 Jul 17;21(1):226
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
Chu F, Wu P, Mu M, Hu S, Niu C
Cell death & disease 2023 Jul 17;14(7):443
Cell death & disease 2023 Jul 17;14(7):443
Mitochondrial pyruvate carrier 1 alleviates hypoxic-ischemic brain injury in rats.
Liu Y, Yuan Y, Yan Y, Wang R, Wang Z, Liu X, Zhang Y, Hua J, Wang Y, Zhao L
Life sciences 2023 Jul 15;325:121686
Life sciences 2023 Jul 15;325:121686
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241
Functional & integrative genomics 2023 Jul 14;23(3):241
Lysophosphatidic acid is associated with oocyte maturation by enhancing autophagy via PI3K-AKT-mTOR signaling pathway in granulosa cells.
Liu J, Wang C
Journal of ovarian research 2023 Jul 11;16(1):137
Journal of ovarian research 2023 Jul 11;16(1):137
Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells.
Han S, Zhang H, Liu X, Wen F, Li B, Bie Z, Qiu H, Hu J
Ecotoxicology and environmental safety 2023 Jul 1;259:115063
Ecotoxicology and environmental safety 2023 Jul 1;259:115063
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Wei Y, Tan W, Qin H, Jin M, Yu H, Cheng J, Feng H
Molecular biology reports 2023 Jan;50(1):97-106
Molecular biology reports 2023 Jan;50(1):97-106
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Xu X, Feng Y, Han C, Yao Z, Liu Y, Luo C, Sheng J
Environmental toxicology 2023 Jan;38(1):205-215
Environmental toxicology 2023 Jan;38(1):205-215
Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice.
Li X, Huang L, Kong L, Su Y, Zhou H, Ji P, Sun R, Wang C, Li W, Li W
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
Unlocking the potential of iridium and ruthenium arene complexes as anti-tumor and anti-metastasis chemotherapeutic agents.
Lv M, Qian X, Li S, Gong J, Wang Q, Qian Y, Su Z, Xue X, Liu HK
Journal of inorganic biochemistry 2023 Jan;238:112057
Journal of inorganic biochemistry 2023 Jan;238:112057
Denosumab Can Prevent Collapse in Patients with Early-Stage Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy.
Liu B, Gao F, Xiu X, Wu T, Liu Z, Zhang B, Liu S, Han Y
Orthopaedic surgery 2023 Jan;15(1):256-265
Orthopaedic surgery 2023 Jan;15(1):256-265
Berberine enhances autophagic flux by activating the Nrf2 signaling pathway in bovine endometrial epithelial cells to resist LPS-induced apoptosis.
Fu K, Chen H, Mei L, Wang J, Gong B, Li Y, Cao R
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13847
Animal science journal = Nihon chikusan Gakkaiho 2023 Jan-Dec;94(1):e13847
Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1.
Liu Y, She W, Li Y, Wang M, Liu Y, Ning B, Xu T, Huang T, Wei Y
Journal of translational medicine 2023 Jan 7;21(1):7
Journal of translational medicine 2023 Jan 7;21(1):7
Long-term copper exposure caused hepatocytes autophagy in broiler via miR-455-3p-OXSR1 axis.
Lei C, Huo Y, Ma F, Liao J, Hu Z, Han Q, Li Y, Pan J, Hu L, Guo J, Tang Z
Chemico-biological interactions 2023 Jan 5;369:110256
Chemico-biological interactions 2023 Jan 5;369:110256
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Wang Y, Yang M, Zhang J, Ren J, Liu N, Liu B, Lu L, Yang B
Biomaterials science 2023 Jan 31;11(3):894-907
Biomaterials science 2023 Jan 31;11(3):894-907
Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.
Meng Z, Lu J, Ge G, Wang G, Zhang R, Li Y, Guan S, Lu J
Food & function 2023 Jan 3;14(1):240-249
Food & function 2023 Jan 3;14(1):240-249
Effects of exogenous spermidine on autophagy and antioxidant capacity in ovaries and granulosa cells of Sichuan white geese.
Jiang D, Sun Q, Jiang Y, Zhou X, Kang L, Wang Z, Wang X, An X, Ji C, Ling W, Wang Y, Yang Y, Kang B
Journal of animal science 2023 Jan 3;101
Journal of animal science 2023 Jan 3;101
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
Sun H, Wang Z, Zhang Q, Chen N, Tang M, Yang Z, Xu Y, Kang J, Wang Y
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae in Apis mellifera.
Chen WF, Wang HF, Wang Y, Liu ZG, Xu BH
International journal of molecular sciences 2023 Jan 20;24(3)
International journal of molecular sciences 2023 Jan 20;24(3)
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Li Q, Fan J, Chen Y, Liu Y, Liu H, Jiang W, Li D, Dang Y
Marine drugs 2023 Jan 20;21(2)
Marine drugs 2023 Jan 20;21(2)
Autophagy induced by Rab1a-ULK1 interaction promotes porcine reproductive and respiratory syndrome virus replication.
Jiang C, Diao F, Ma Z, Zhang J, Bai J, Nauwynck H, Jiang P, Liu X
Virus research 2023 Jan 2;323:198989
Virus research 2023 Jan 2;323:198989
Newly identified lncRNA-45 promotes breast cancer metastasis through activating the mTOR signaling pathway.
Qiu J, Guo Y, Wang S, Ren Q, Dong Z, Gao M, Ma J, Chen S, Liu S
Biochemical and biophysical research communications 2023 Jan 15;640:40-49
Biochemical and biophysical research communications 2023 Jan 15;640:40-49
The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
Zhang J, Tang Y, Hu Z, Xu W, Ma Y, Xu P, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Jan 15;250:114511
Ecotoxicology and environmental safety 2023 Jan 15;250:114511
Cross-talk between autophagy and ferroptosis contributes to the liver injury induced by fluoride via the mtROS-dependent pathway.
Xu W, Hu Z, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Jan 15;250:114490
Ecotoxicology and environmental safety 2023 Jan 15;250:114490
Exogenous H(2)S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, Wang Y, Chen H, Zhang W
International journal of molecular sciences 2023 Jan 14;24(2)
International journal of molecular sciences 2023 Jan 14;24(2)
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Hu A, Liu J, Wang Y, Zhang M, Guo Y, Qin Y, Liu T, Men Y, Chen Q, Liu T
Scientific reports 2023 Jan 13;13(1):693
Scientific reports 2023 Jan 13;13(1):693
Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer.
Zhang X, Hong S, Yang J, Liu J, Wang Y, Peng J, Wang H, Hong L
Anti-cancer drugs 2023 Jan 1;34(1):29-43
Anti-cancer drugs 2023 Jan 1;34(1):29-43
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.
Zhang C, Deng Y, Zhang Y, Ba T, Niu S, Chen Y, Gao Y, Dai H
Cells 2023 Jan 1;12(1)
Cells 2023 Jan 1;12(1)
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway.
Ran X, Lu QY, Li YY, Pu XX, Guo Y, Yuan MR, Guan SP, Sun M, Jiao L, Yao YG, Di YT, Hao XJ, Luo R
Heliyon 2023 Feb;9(2):e13691
Heliyon 2023 Feb;9(2):e13691
RBM3 interacts with Raptor to regulate autophagy and protect cardiomyocytes from ischemia-reperfusion-induced injury.
Wang N, Wang L, Li C, Rao P, Wang X, Xu Y, Yang L, Sun L, Lu D
Journal of physiology and biochemistry 2023 Feb;79(1):47-57
Journal of physiology and biochemistry 2023 Feb;79(1):47-57
Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival.
Yang J, Chen Y, Zou T, Xue B, Yang F, Wang X, Huo Y, Yan B, Xu Y, He S, Yin Y, Wang J, Zhu X, Zhang L, Zhou Y, Tai Z, Shuai P, Yu M, Luo Q, Cheng Y, Gong B, Zhu X, Zhang J, Sun X, Lin Y, Zhang H, Yang Z
Science China. Life sciences 2023 Feb;66(2):211-225
Science China. Life sciences 2023 Feb;66(2):211-225
The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.
Ding X, Hou Y, Liu X, Li X, Liu X, Deng Y, Cao N, Yu W
Journal of periodontal research 2023 Feb;58(1):97-108
Journal of periodontal research 2023 Feb;58(1):97-108
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Zhang T, Yang K, Chen Y, Jiang Y, Zhou Z, Liu J, Du Y, Wang L, Han X, Wu X, Wang X
Journal of periodontal research 2023 Feb;58(1):70-82
Journal of periodontal research 2023 Feb;58(1):70-82
Strontium ion attenuates osteoarthritis through inhibiting senescence and enhancing autophagy in fibroblast-like synoviocytes.
Liao B, Ding M, Wang Y, Xu H, Shangguan L
Molecular biology reports 2023 Feb;50(2):1437-1446
Molecular biology reports 2023 Feb;50(2):1437-1446
DANCR promotes glioma cell autophagy and proliferation via the miR‑33b/DLX6/ATG7 axis.
Yu W, Ma L, Li X
Oncology reports 2023 Feb;49(2)
Oncology reports 2023 Feb;49(2)
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Liu L, Wang J, Zhang J, Huang C, Yang Z, Cao Y
Cell biology and toxicology 2023 Feb;39(1):259-275
Cell biology and toxicology 2023 Feb;39(1):259-275
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Fang Q, Zheng S, Chen Q, Chen L, Yang Y, Wang Y, Zhang H, Chen J
Metabolic brain disease 2023 Feb;38(2):453-466
Metabolic brain disease 2023 Feb;38(2):453-466
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Li B, Li W, Zheng M, Wang Y, Diao Y, Mou X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Li Y, She W, Guo T, Huang T, Liu Y, Liu P, Xu X, Wang X, Wang M, Yu C, Liu Y, Wei Y
Biochemical pharmacology 2023 Feb;208:115404
Biochemical pharmacology 2023 Feb;208:115404
Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC.
Zhao Z, Xu H, Wei Y, Sun L, Song Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Feb;1869(2):166594
Biochimica et biophysica acta. Molecular basis of disease 2023 Feb;1869(2):166594
Chloroquine is a safe autophagy inhibitor for sustaining the expression of antioxidant enzymes in trophoblasts.
Furuta A, Shima T, Yoshida-Kawaguchi M, Yamada K, Yasuda I, Tsuda S, Yamaki-Ushijima A, Yoneda S, Higashisaka K, Cheng SB, Matsumoto K, Tsutsumi Y, Sharma S, Saito S, Nakashima A
Journal of reproductive immunology 2023 Feb;155:103766
Journal of reproductive immunology 2023 Feb;155:103766
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
Gao X, Gao LF, Kong XQ, Zhang YN, Jia S, Meng CY
International immunopharmacology 2023 Feb;115:109695
International immunopharmacology 2023 Feb;115:109695
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Zhu D, Kong M, Chen C, Luo J, Kong L
International immunopharmacology 2023 Feb;115:109689
International immunopharmacology 2023 Feb;115:109689
Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity.
Liu XM, Li Z, Xie XR, Wang JQ, Qiao X, Qiao X, Xie CZ, Xu JY
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
Journal of medicinal chemistry 2023 Feb 9;66(3):1852-1872
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Man Y, Liu Y, Xiong C, Zhang Y, Zhang L
Toxics 2023 Feb 9;11(2)
Toxics 2023 Feb 9;11(2)
Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM Pathway.
Han X, Wang J, Li R, Huang M, Yue G, Guan L, Deng Y, Cai W, Xu J
International journal of molecular sciences 2023 Feb 28;24(5)
International journal of molecular sciences 2023 Feb 28;24(5)
Autophagy-Related Gene WD Repeat Domain 45B Promotes Tumor Proliferation and Migration of Hepatocellular Carcinoma through the Akt/mTOR Signaling Pathway.
Li J, Chen L, Pang J, Yang C, Xie W, Shen G, Chen H, Li X, Xiao SY, Li Y
Diagnostics (Basel, Switzerland) 2023 Feb 27;13(5)
Diagnostics (Basel, Switzerland) 2023 Feb 27;13(5)
Osteogenic effects of rapamycin on bone marrow mesenchymal stem cells via inducing autophagy.
Xing Y, Liu C, Zhou L, Li Y, Wu D
Journal of orthopaedic surgery and research 2023 Feb 22;18(1):129
Journal of orthopaedic surgery and research 2023 Feb 22;18(1):129
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Chen SJ, Huang Y, Yu F, Feng X, Zheng YY, Li Q, Niu Q, Jiang YH, Zhao LQ, Wang M, Cheng PP, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Metformin regulates autophagy via LGMN to inhibit choriocarcinoma.
Tu W, Qin M, Li Y, Wu W, Tong X
Gene 2023 Feb 15;853:147090
Gene 2023 Feb 15;853:147090
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, Chen J, Sun Z, He P
Experimental cell research 2023 Feb 15;423(2):113469
Experimental cell research 2023 Feb 15;423(2):113469
MLKL deficiency attenuated hepatocyte oxidative DNA damage by activating mitophagy to suppress macrophage cGAS-STING signaling during liver ischemia and reperfusion injury.
Xu J, Wu D, Zhou S, Hu H, Li F, Guan Z, Zhan X, Gao Y, Wang P, Rao Z
Cell death discovery 2023 Feb 10;9(1):58
Cell death discovery 2023 Feb 10;9(1):58
Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling.
Yan J, Feng G, Yang Y, Ding D, Ma L, Zhao X, Chen X, Wang H, Chen Z, Jin Q
Biomolecules & biomedicine 2023 Feb 1;23(1):77-88
Biomolecules & biomedicine 2023 Feb 1;23(1):77-88
Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways.
Chen T, Bao S, Chen J, Zhang J, Wei H, Hu X, Liang Y, Li J, Yan S
Pharmaceutical biology 2023 Dec;61(1):1234-1248
Pharmaceutical biology 2023 Dec;61(1):1234-1248
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Xu Y, Wang Y, Xiao H, Li Y
Journal of periodontal research 2023 Dec;58(6):1248-1260
Journal of periodontal research 2023 Dec;58(6):1248-1260
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways.
Shen Y, Li X, Wang H, Wang Y, Tao L, Wang P, Zhang H
Toxicology 2023 Dec;500:153678
Toxicology 2023 Dec;500:153678
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis.
Zheng GP, Liu C, Zhang L, Zhong Q, Zhang Y, Huang ZM
Current medical science 2023 Dec;43(6):1195-1200
Current medical science 2023 Dec;43(6):1195-1200
Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity.
Sun X, Du J, Meng H, Liu F, Yang N, Deng S, Wan H, Ye D, Song E, Zeng H
Cell biology and toxicology 2023 Dec;39(6):3255-3267
Cell biology and toxicology 2023 Dec;39(6):3255-3267
Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma.
He F, Chen J, Zhao T, Wu Q, Yin N, Wang X, Zhong Y, Guo X, Qiu Y, Li B, Fang M, Wu Z
Journal of enzyme inhibition and medicinal chemistry 2023 Dec;38(1):2227777
Journal of enzyme inhibition and medicinal chemistry 2023 Dec;38(1):2227777
Activation of moderate autophagy promotes survival of fat graft.
Pei SJ, Zhu YZ, Yang JM, Zhang MC, Shi CL, Ding Y, Yi YY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23289
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23289
Ame-miR-980-3p participates in autophagy-mediated midgut remodelling in Apis mellifera via targeting Atg2B.
Chen WF, Chi XP, Song HY, Wang HF, Wang Y, Liu ZG, Xu BH
Insect molecular biology 2023 Dec;32(6):748-760
Insect molecular biology 2023 Dec;32(6):748-760
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway.
Xiong Y, Huang CW, Shi C, Peng L, Cheng YT, Hong W, Liao J
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2363-2380
Experimental biology and medicine (Maywood, N.J.) 2023 Dec;248(23):2363-2380
HD-sEVs in bovine follicular fluid regulate granulosa cell apoptosis and estradiol secretion through the autophagy pathway.
Wang Y, Zhao Y, Ling Z, Luan D, Kang J, Dong X, Quan F
Theriogenology 2023 Dec;212:91-103
Theriogenology 2023 Dec;212:91-103
Ginsenoside Rb2 improves heart failure by down-regulating miR-216a-5p to promote autophagy and inhibit apoptosis and oxidative stress.
Peng Y, Liao B, Zhou Y, Zeng W
Journal of applied biomedicine 2023 Dec;21(4):180-192
Journal of applied biomedicine 2023 Dec;21(4):180-192
Exogenous H(2)S alleviates senescence of glomerular mesangial cells through up-regulating mitophagy by activation of AMPK-ULK1-PINK1-parkin pathway in mice.
E Y, Lin Y, Yan G, Yang J, Jiao L, Wu R, Yan Q, Chen Y, Chen Y, Yan X, Li H
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119568
Biochimica et biophysica acta. Molecular cell research 2023 Dec;1870(8):119568
ZnO nanoparticles impair autophagic flux and cell viability through the TRIM16-NRF2-p62 pathway in inflammatory keratinocytes.
Wang M, Zheng H, Chen J, Tang Y, Feng M, Li L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114177
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114177
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway.
Chen Y, Liu M, Wei H, Guo J, Zhang S, Bu X, Chen S, Zhang D, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114124
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114124
Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells.
Wang D, Han S, Lv G, Hu Y, Zhuo W, Zeng Z, Tang J, Huang Y, Wang F, Wang J, Zhao Y, Zhao G
Gastroenterology 2023 Dec;165(6):1488-1504.e20
Gastroenterology 2023 Dec;165(6):1488-1504.e20
Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis.
Wang R, Liu SL, Guo QQ, Shi XH, Ma MM
World journal of oncology 2023 Dec;14(6):464-475
World journal of oncology 2023 Dec;14(6):464-475
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Xue R, Fan XL, Yang Q, Yu C, Lu TY, Wan GM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Gou Q, Chen H, Chen M, Shi J, Jin J, Liu Q, Hou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
COPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy.
Nie J, Ma S, Zhang Y, Yu S, Yang J, Li A, Pei D
International journal of molecular sciences 2023 Dec 26;25(1)
International journal of molecular sciences 2023 Dec 26;25(1)
The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication.
Zhang S, Zeng L, Su B-Q, Yang G-Y, Wang J, Ming S-L, Chu B-B
mBio 2023 Dec 19;14(6):e0265123
mBio 2023 Dec 19;14(6):e0265123
Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.
Zhu H, Cheng Y, Wang X, Yang X, Liu M, Liu J, Liu S, Wang H, Zhang A, Li R, Ye C, Zhang J, Gao J, Fu X, Wu B
Cell death & disease 2023 Dec 19;14(12):845
Cell death & disease 2023 Dec 19;14(12):845
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
Furthmann N, Bader V, Angersbach L, Blusch A, Goel S, Sánchez-Vicente A, Krause LJ, Chaban SA, Grover P, Trinkaus VA, van Well EM, Jaugstetter M, Tschulik K, Damgaard RB, Saft C, Ellrichmann G, Gold R, Koch A, Englert B, Westenberger A, Klein C, Jungbluth L, Sachse C, Behrends C, Glatzel M, Hartl FU, Nakamura K, Christine CW, Huang EJ, Tatzelt J, Winklhofer KF
Nature communications 2023 Dec 19;14(1):8368
Nature communications 2023 Dec 19;14(1):8368
Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats.
Pai MS, Wang KC, Yeh KC, Wang SJ
European journal of pharmacology 2023 Dec 15;961:176197
European journal of pharmacology 2023 Dec 15;961:176197
Targeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer.
Zhang G, Mi W, Wang C, Li J, Zhang Y, Liu N, Jiang M, Jia G, Wang F, Yang G, Zhang L, Wang J, Fu Y, Zhang Y
Cell death discovery 2023 Dec 15;9(1):457
Cell death discovery 2023 Dec 15;9(1):457
Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis.
Liu J, Sun Y, Chen W, Deng L, Chen M, Dong J
BMC complementary medicine and therapies 2023 Dec 15;23(1):461
BMC complementary medicine and therapies 2023 Dec 15;23(1):461
Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
Wang W, Gao W, Gong P, Song W, Bu X, Hou J, Zhang L, Zhao B
Cell communication and signaling : CCS 2023 Dec 15;21(1):356
Cell communication and signaling : CCS 2023 Dec 15;21(1):356
Quantitative transcriptomic and proteomic analysis reveals corosolic acid inhibiting bladder cancer via suppressing cell cycle and inducing mitophagy in vitro and in vivo.
Cui A, Li X, Ma X, Song Z, Wang X, Wang C, Xia Y
Toxicology and applied pharmacology 2023 Dec 1;480:116749
Toxicology and applied pharmacology 2023 Dec 1;480:116749
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
Wang Y, Li B, Liu G, Han Q, Diao Y, Liu J
Life sciences 2023 Dec 1;334:122176
Life sciences 2023 Dec 1;334:122176
Temporal Dynamic Regulation of Autophagy and Senescence Induction in Response to Radiation Exposure.
Noguchi M, Ihara T, Suzuki K, Yokoya A
Radiation research 2023 Dec 1;200(6):538-547
Radiation research 2023 Dec 1;200(6):538-547
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Cui Z, Qin R, Feng J, Liu Y, Zhou X, Qin X, Li Y, Zhang Z, He X
Tissue & cell 2023 Aug;83:102139
Tissue & cell 2023 Aug;83:102139
Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis.
Dong L, Sun Q, Qiu H, Yang K, Xiao B, Xia T, Wang A, Gao H, Zhang S
Journal of pineal research 2023 Aug;75(1):e12871
Journal of pineal research 2023 Aug;75(1):e12871
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
Fluoride-Induced Cortical Toxicity in Rats: the Role of Excessive Endoplasmic Reticulum Stress and Its Mediated Defective Autophagy.
Zhang J, Tang Y, Xu W, Hu Z, Xu S, Niu Q
Biological trace element research 2023 Aug;201(8):3850-3860
Biological trace element research 2023 Aug;201(8):3850-3860
The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP.
Wang T, Luo R, Zhang J, Lu Z, Li LF, Zheng YH, Pan L, Lan J, Zhai H, Huang S, Sun Y, Qiu HJ
PLoS pathogens 2023 Aug;19(8):e1011580
PLoS pathogens 2023 Aug;19(8):e1011580
Nanozyme-Integrated Thermoresponsive In Situ Forming Hydrogel Enhances Mesenchymal Stem Cell Viability and Paracrine Effect for Efficient Spinal Cord Repair.
Xu L, Mu J, Ma Z, Lin P, Xia F, Hu X, Wu J, Cao J, Liu S, Huang T, Ling D, Gao J, Li F
ACS applied materials & interfaces 2023 Aug 9;15(31):37193-37204
ACS applied materials & interfaces 2023 Aug 9;15(31):37193-37204
Interaction of L1CAM with LC3 Is Required for L1-Dependent Neurite Outgrowth and Neuronal Survival.
Loers G, Kleene R, Granato V, Bork U, Schachner M
International journal of molecular sciences 2023 Aug 7;24(15)
International journal of molecular sciences 2023 Aug 7;24(15)
Curcumin in vitro Neuroprotective Effects Are Mediated by p62/keap-1/Nrf2 and PI3K/AKT Signaling Pathway and Autophagy Inhibition.
Li X, Sung P, Zhang D, Yan L
Physiological research 2023 Aug 31;72(4):497-510
Physiological research 2023 Aug 31;72(4):497-510
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
Small cytosolic double-stranded DNA represses cyclic GMP-AMP synthase activation and induces autophagy.
Liu Y, Chen X, Zhao Y, Wang XY, Luo YW, Chen L, Wang W, Zhong S, Hu M, Dai Z, Jiang J, Wang X, Ji H, Cheng XX, Zheng A, Zuo J, Liu H, Ma D, Luo Z, Cao F, Hu S, Huang AL, Tang KF
Cell reports 2023 Aug 29;42(8):112852
Cell reports 2023 Aug 29;42(8):112852
Sarmentosin Induces Autophagy-dependent Apoptosis via Activation of Nrf2 in Hepatocellular Carcinoma.
Jiang Z, Gao L, Liu C, Wang J, Han Y, Pan J
Journal of clinical and translational hepatology 2023 Aug 28;11(4):863-876
Journal of clinical and translational hepatology 2023 Aug 28;11(4):863-876
α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis.
Wang P, Lan G, Xu B, Yu Z, Tian C, Lei X, Meissner WG, Feng T, Yang Y, Zhang J
Translational neurodegeneration 2023 Aug 25;12(1):40
Translational neurodegeneration 2023 Aug 25;12(1):40
Liquiritigenin Confers Liver Protection by Enhancing NRF2 Signaling through Both Canonical and Non-canonical Signaling Pathways.
Shi M, Zhang J, Li M, Zhao Y, Guo Y, Xu J, Liu R, Li Z, Ren D, Liu P
Journal of medicinal chemistry 2023 Aug 24;66(16):11324-11334
Journal of medicinal chemistry 2023 Aug 24;66(16):11324-11334
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Ji L, Zhang L, Liang Z, Zhong S, Liu X, Liu Z, Poon WS, Song Y, Chen B, Wang R
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Molecular and cellular endocrinology 2023 Aug 20;574:111990
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Su H, Zhang C
Journal of translational medicine 2023 Aug 2;21(1):521
Journal of translational medicine 2023 Aug 2;21(1):521
Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease.
Li D, Dun Y, Qi D, Ripley-Gonzalez JW, Dong J, Zhou N, Qiu L, Zhang J, Zeng T, You B, Liu S
Scientific reports 2023 Aug 11;13(1):13068
Scientific reports 2023 Aug 11;13(1):13068
Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.
Zhang PP, Zhuo BY, Duan ZW, Li X, Huang SL, Cao Q, Zhao T, Wei SL, Hu XH, Zhang Y
Journal of ethnopharmacology 2023 Aug 10;312:116523
Journal of ethnopharmacology 2023 Aug 10;312:116523
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity.
Guan X, Wang Y, Li W, Liu X, Jiang J, Bian W, Xu C, Sun Y, Zhang C
Toxicology 2023 Aug 1;494:153587
Toxicology 2023 Aug 1;494:153587
Nrf2 protects against methamphetamine-induced nephrotoxicity by mitigating oxidative stress and autophagy in mice.
Dong W, Wan J, Yu H, Shen B, Yang G, Nie Q, Tian Y, Qin L, Song C, Chen B, Li L, Hong S
Toxicology letters 2023 Aug 1;384:136-148
Toxicology letters 2023 Aug 1;384:136-148
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease.
Wang X, Song M, Li X, Su C, Yang Y, Wang K, Liu C, Zheng Z, Jia Y, Ren S, Dong W, Chen J, Wang T, Liu L, Guan M, Zhang C, Xue Y
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C538-C549
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C538-C549
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Zheng Y, Zhan Y, Zhang Y, Zhang Y, Liu Y, Xie Y, Sun Y, Qian J, Ding Y, Ding Y, Fang Y
Cell death & disease 2023 Aug 1;14(8):488
Cell death & disease 2023 Aug 1;14(8):488
Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease.
Ballesteros-Álvarez J, Nguyen W, Sivapatham R, Rane A, Andersen JK
GeroScience 2023 Apr;45(2):1095-1113
GeroScience 2023 Apr;45(2):1095-1113
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway.
Song CF, Hu YH, Mang ZG, Ye Z, Chen HD, Jing DS, Fan GX, Ji SR, Yu XJ, Xu XW, Qin Y
Acta pharmacologica Sinica 2023 Apr;44(4):865-876
Acta pharmacologica Sinica 2023 Apr;44(4):865-876
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
Li X, Li Y, Liu B, Chen L, Lyu F, Zhang P, He Q, Cheng L, Liu C, Song Y, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Apr;37(4):e22840
Abamectin causes toxicity to the carp respiratory system by triggering oxidative stress, inflammation, and apoptosis and inhibiting autophagy.
Feng H, Zhou P, Liu F, Zhang W, Yang H, Li X, Dong J
Environmental science and pollution research international 2023 Apr;30(19):55200-55213
Environmental science and pollution research international 2023 Apr;30(19):55200-55213
ETNPPL impairs autophagy through regulation of the ARG2-ROS signaling axis, contributing to palmitic acid-induced hepatic insulin resistance.
Wang C, Li X, Zhang W, Liu W, Lv Z, Gui R, Li M, Li Y, Sun X, Liu P, Fan X, Yang S, Xiong Y, Qian L
Free radical biology & medicine 2023 Apr;199:126-140
Free radical biology & medicine 2023 Apr;199:126-140
Crosstalk between Mfn2-mediated mitochondria associated membranes disorder and autophagy induced by molybdenum and cadmium in sheep heart.
Peng C, Yang S, Yang F, Xiong Z, Liu Q, Liao S, Huang K, Wan W, Cao H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113660
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113660
Jiedu Tongluo Baoshen formula enhances renal tubular epithelial cell autophagy to prevent renal fibrosis by activating SIRT1/LKB1/AMPK pathway.
Jin D, Zhao Y, Sun Y, Xue J, Li X, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114340
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114340
Mesenchymal stromal cells ameliorate diabetes-induced muscle atrophy through exosomes by enhancing AMPK/ULK1-mediated autophagy.
Song J, Liu J, Cui C, Hu H, Zang N, Yang M, Yang J, Zou Y, Li J, Wang L, He Q, Guo X, Zhao R, Yan F, Liu F, Hou X, Sun Z, Chen L
Journal of cachexia, sarcopenia and muscle 2023 Apr;14(2):915-929
Journal of cachexia, sarcopenia and muscle 2023 Apr;14(2):915-929
A Novel Tri-Functional Liposome Re-Educates "Cold Tumor" and Abrogates Tumor Growth by Synergizing Autophagy Inhibition and PD-L1 Blockade.
Zhou F, Li X, Xue X, Li S, Fan G, Cai Y, Chang Z, Qu J, Liu R
Advanced healthcare materials 2023 Apr;12(11):e2202757
Advanced healthcare materials 2023 Apr;12(11):e2202757
Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Huang R, Cai L, Ma X, Shen K
International immunopharmacology 2023 Apr;117:109907
International immunopharmacology 2023 Apr;117:109907
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Tan H, Cao L
Immunity, inflammation and disease 2023 Apr;11(4):e830
Immunity, inflammation and disease 2023 Apr;11(4):e830
Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy.
Tan HY, Liang FM, Zhang WJ, Zhang Y, Cui JH, Dai YY, Qiu XM, Wang WH, Zhou Y, Chen DP, Li CP
Molecules (Basel, Switzerland) 2023 Apr 7;28(8)
Molecules (Basel, Switzerland) 2023 Apr 7;28(8)
Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.
Wang W, Zhao B, Gao W, Song W, Hou J, Zhang L, Xia Z
ACS chemical neuroscience 2023 Apr 5;14(7):1249-1260
ACS chemical neuroscience 2023 Apr 5;14(7):1249-1260
HCMV-encoded viral protein US12 promotes autophagy by inducing autophagy flux.
Kim HJ, Lee Y, Lee S, Park B
Biochemical and biophysical research communications 2023 Apr 30;654:94-101
Biochemical and biophysical research communications 2023 Apr 30;654:94-101
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Tang Y, Zhang J, Hu Z, Xu W, Xu P, Ma Y, Xing H, Niu Q
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Ecotoxicology and environmental safety 2023 Apr 15;255:114772
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
Cai W, Sun B, Song C, Liu F, Wu Z, Liu Z
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
BMC complementary medicine and therapies 2023 Apr 14;23(1):121
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Ma Z, Liu Z, Li X, Zhang H, Han D, Xiong W, Zhou H, Yang X, Zeng Q, Ren H, Xu D
Biology 2023 Apr 11;12(4)
Biology 2023 Apr 11;12(4)
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Blue LED light induces cytotoxicity via ROS production and mitochondrial damage in bovine subcutaneous preadipocytes.
Hao W, Zhao C, Li G, Wang H, Li T, Yan P, Wei S
Environmental pollution (Barking, Essex : 1987) 2023 Apr 1;322:121195
Environmental pollution (Barking, Essex : 1987) 2023 Apr 1;322:121195
Dysregulated autophagy-related genes in septic cardiomyopathy: Comprehensive bioinformatics analysis based on the human transcriptomes and experimental validation.
Zou HX, Qiu BQ, Zhang ZY, Hu T, Wan L, Liu JC, Huang H, Lai SQ
Frontiers in cardiovascular medicine 2022;9:923066
Frontiers in cardiovascular medicine 2022;9:923066
The KLF4-p62 axis prevents vascular endothelial cell injury via the mTOR/S6K pathway and autophagy in diabetic kidney disease.
Wang X, Su W, Ma M, Zhu L, Gao R, Qin C, Shao S, Gao D, Gao J, Zhang Z
Endokrynologia Polska 2022;73(5):837-845
Endokrynologia Polska 2022;73(5):837-845
Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy.
Zhang H, Jia S, Jin L, Mb JY, Shen Z, Wu J, Yao X, Chen D, Zhang C, Yu S, Zhu N, Jin L, Yao X
Acta cirurgica brasileira 2022;36(11):e361104
Acta cirurgica brasileira 2022;36(11):e361104
BRD4 Inhibition Suppresses Senescence and Apoptosis of Nucleus Pulposus Cells by Inducing Autophagy during Intervertebral Disc Degeneration: An In Vitro and In Vivo Study.
Zhang GZ, Chen HW, Deng YJ, Liu MQ, Wu ZL, Ma ZJ, He XG, Gao YC, Kang XW
Oxidative medicine and cellular longevity 2022;2022:9181412
Oxidative medicine and cellular longevity 2022;2022:9181412
Resveratrol Synergistically Promotes BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells.
Wang Y, Xia C, Chen Y, Jiang T, Hu Y, Gao Y
Stem cells international 2022;2022:8124085
Stem cells international 2022;2022:8124085
Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells.
Liang J, Chen B, Li Y, Nie D, Lei C, Yang Q, Zhou Y, Li S, Chen S, Li B, Shu L, Chen L, Wang W
Stem cells international 2022;2022:6795573
Stem cells international 2022;2022:6795573
Artemisinin Alleviates Cerebral Ischemia/Reperfusion-Induced Oxidative Damage via Regulating PHB2-Mediated Autophagy in the Human Neuroblastoma SH-SY5Y Cell Line.
Jiang M, Lai X, Zhang Y, Shen M, Ma H, Liu A, Wu J, Yan J
Oxidative medicine and cellular longevity 2022;2022:6568748
Oxidative medicine and cellular longevity 2022;2022:6568748
Astragaloside IV Protects Detrusor from Partial Bladder Outlet Obstruction-Induced Oxidative Stress by Activating Mitophagy through AMPK-ULK1 Pathway.
Zhu X, Tao F, Zhang L, Yu Y, Xu Y, Yang G, Wei Z, Cheng Y, Yin X, Zhang X, Wei W, Wang A
Oxidative medicine and cellular longevity 2022;2022:5757367
Oxidative medicine and cellular longevity 2022;2022:5757367
Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy.
Jiang RH, Dong CJ, Chen ZL, Cheng S, Yang JX, Gao WY
Oxidative medicine and cellular longevity 2022;2022:5668226
Oxidative medicine and cellular longevity 2022;2022:5668226
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Han GJ, Min XZ, Ma SS, Ding C, Wang XQ
Oxidative medicine and cellular longevity 2022;2022:5126042
Oxidative medicine and cellular longevity 2022;2022:5126042
Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway.
Sun H, Wang J, Bi W, Zhang F, Chi K, Shi L, Yuan T, Ma K, Gao X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4653864
Evidence-based complementary and alternative medicine : eCAM 2022;2022:4653864
SIRT2 Affects Cell Proliferation and Apoptosis by Suppressing the Level of Autophagy in Renal Podocytes.
Liu S, Gao X, Fan Z, Wang Q
Disease markers 2022;2022:4586198
Disease markers 2022;2022:4586198
Transcutaneous Electrical Acupoint Stimulation Ameliorates Cognitive Function through PINK1/Parkin Mediated Mitophagy in VD Rats.
Hu Z, Wen T, Hu K, Wang R, Su X, Ouyang W, Zhou J, Wen Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2810794
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Li H, Wang Y, Su X, Wang Q, Zhang S, Sun W, Zhang T, Dong M, Zhang Z, Lv S
Journal of diabetes research 2022;2022:2640209
Journal of diabetes research 2022;2022:2640209
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2502263
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Meng X, Li M, Qiao M, Li X, Yang J, Hu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Shi Y, Li H, Wu T, Wang Q, Zhu Q, Guan X, Wu R
Oxidative medicine and cellular longevity 2022;2022:1509421
Oxidative medicine and cellular longevity 2022;2022:1509421
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Mao Y, Du J, Chen X, Al Mamun A, Cao L, Yang Y, Mubwandarikwa J, Zaeem M, Zhang W, Chen Y, Dai Y, Xiao J, Ye K
Oxidative medicine and cellular longevity 2022;2022:1337630
Oxidative medicine and cellular longevity 2022;2022:1337630
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y
International journal of biological sciences 2022;18(6):2639-2651
International journal of biological sciences 2022;18(6):2639-2651
GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway.
Lu J, Chen PP, Zhang JX, Li XQ, Wang GH, Yuan BY, Huang SJ, Liu XQ, Jiang TT, Wang MY, Liu WT, Ruan XZ, Liu BC, Ma KL
International journal of biological sciences 2022;18(1):96-111
International journal of biological sciences 2022;18(1):96-111
The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease.
Shearn CT, Anderson AL, Devereux MW, Orlicky DJ, Michel C, Petersen DR, Miller CG, Harpavat S, Schmidt EE, Sokol RJ
PloS one 2022;17(11):e0276879
PloS one 2022;17(11):e0276879
Beclin1 Deficiency Suppresses Epileptic Seizures.
Yang M, Lin P, Jing W, Guo H, Chen H, Chen Y, Guo Y, Gu Y, He M, Wu J, Jiang X, Zou Z, Xu X, Chen C, Xiao F, Wang X, Tian X
Frontiers in molecular neuroscience 2022;15:807671
Frontiers in molecular neuroscience 2022;15:807671
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Zhong F, Gan Y, Song J, Zhang W, Yuan S, Qin Z, Wu J, Lü Y, Yu W
Frontiers in molecular neuroscience 2022;15:1047801
Frontiers in molecular neuroscience 2022;15:1047801
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Zheng X, Liu B, Liu X, Li P, Zhang P, Ye F, Zhao T, Kuang Y, Chen W, Jin X, Li Q
Journal of Cancer 2022;13(2):669-680
Journal of Cancer 2022;13(2):669-680
The role of APTX4870 peptide in reducing cellular inflammatory responses by inhibiting Mycobacterium tuberculosis-derived mycolic acid-induced cytotoxicity.
Lin X, Jia W, Feng G, Su Y, Kang Y, Zhang C, Liu W, Lu Z, Xue D
Frontiers in microbiology 2022;13:993897
Frontiers in microbiology 2022;13:993897
Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy.
Li YY, Tian ZH, Pan GH, Zhao P, Pan DJ, Zhang JQ, Ye LY, Zhang FR, Xu XD
Frontiers in pharmacology 2022;13:977284
Frontiers in pharmacology 2022;13:977284
LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2.
Zhang C, Kang T, Wang X, Wang J, Liu L, Zhang J, Liu X, Li R, Wang J, Zhang J
Frontiers in pharmacology 2022;13:968223
Frontiers in pharmacology 2022;13:968223
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo.
Fan H, Hao X, Gao Y, Yang J, Liu A, Su Y, Xia Y
Frontiers in pharmacology 2022;13:943272
Frontiers in pharmacology 2022;13:943272
Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway.
Zhao W, Xu M, Barkema HW, Xie X, Lin Y, Khan S, Kastelic JP, Wang D, Deng Z, Han B
Frontiers in immunology 2022;13:934819
Frontiers in immunology 2022;13:934819
Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma.
Xiu Z, Zhu Y, Han J, Li Y, Yang X, Yang G, Song G, Li S, Li Y, Cheng C, Li Y, Fang J, Li X, Jin N
Frontiers in pharmacology 2022;13:930958
Frontiers in pharmacology 2022;13:930958
Src Activation Aggravates Podocyte Injury in Diabetic Nephropathy via Suppression of FUNDC1-Mediated Mitophagy.
Zheng T, Wang HY, Chen Y, Chen X, Wu ZL, Hu QY, Sun H
Frontiers in pharmacology 2022;13:897046
Frontiers in pharmacology 2022;13:897046
Astragalus-Scorpion Drug Pair Inhibits the Development of Prostate Cancer by Regulating GDPD4-2/PI3K/AKT/mTOR Pathway and Autophagy.
You X, Wu Y, Li Q, Sheng W, Zhou Q, Fu W
Frontiers in pharmacology 2022;13:895696
Frontiers in pharmacology 2022;13:895696
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Xin M, Gao Q, Xiang X, Xu J, Jiao Y, Li X, Zhang X, Jia X
Frontiers in pharmacology 2022;13:890974
Frontiers in pharmacology 2022;13:890974
Melatonin alleviates renal injury by activating mitophagy in diabetic nephropathy.
Tang H, Yang M, Liu Y, Zhu X, Liu S, Liu H, Sun L, Song P
Frontiers in endocrinology 2022;13:889729
Frontiers in endocrinology 2022;13:889729
Protocatechualdehyde Rescues Oxygen-Glucose Deprivation/Reoxygenation-Induced Endothelial Cells Injury by Inducing Autophagy and Inhibiting Apoptosis via Regulation of SIRT1.
Cao S, Chen S, Qiao X, Guo Y, Liu F, Ding Z, Jin B
Frontiers in pharmacology 2022;13:846513
Frontiers in pharmacology 2022;13:846513
TMT-Based Quantitative Proteomics Analysis Reveals the Panoramic Pharmacological Molecular Mechanism of β-Elemonic Acid Inhibition of Colorectal Cancer.
Xia Y, Yang J, Li C, Hao X, Fan H, Zhao Y, Tang J, Wan X, Lian S, Yang J
Frontiers in pharmacology 2022;13:830328
Frontiers in pharmacology 2022;13:830328
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Dong C, Chen Z, Zhu L, Bsoul N, Wu H, Jiang J, Chen X, Lai Y, Yu G, Gu Y, Guo X, Gao W
Frontiers in pharmacology 2022;13:809034
Frontiers in pharmacology 2022;13:809034
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment.
Zhao X, Jiang Y, Ren J, Wang Y, Zhao Y, Feng X
Frontiers in pharmacology 2022;13:794938
Frontiers in pharmacology 2022;13:794938
Transcriptome Analysis Reveal Candidate Genes and Pathways Responses to Lactate Dehydrogenase Inhibition (Oxamate) in Hyperglycemic Human Renal Proximal Epithelial Tubular Cells.
Wang Z, Hao D, Fang D, Yu J, Wang X, Qin G
Frontiers in endocrinology 2022;13:785605
Frontiers in endocrinology 2022;13:785605
Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats.
Ma T, Lv L, Yu Y, Jia L, Song X, Xu X, Li T, Sheng X, Wang H, Zhang J, Gao L
Frontiers in pharmacology 2022;13:783506
Frontiers in pharmacology 2022;13:783506
Creatine modulates cellular energy metabolism and protects against cancer cachexia-associated muscle wasting.
Wei L, Wang R, Lin K, Jin X, Li L, Wazir J, Pu W, Lian P, Lu R, Song S, Zhao Q, Li J, Wang H
Frontiers in pharmacology 2022;13:1086662
Frontiers in pharmacology 2022;13:1086662
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells.
Qu N, Qu J, Huang N, Zhang K, Ye T, Shi J, Chen B, Kan C, Zhang J, Han F, Hou N, Sun X, Pan R
Frontiers in pharmacology 2022;13:1056687
Frontiers in pharmacology 2022;13:1056687
Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus.
Wang Y, Huang M, Xu W, Li F, Ma C, Tang X
Frontiers in endocrinology 2022;13:1051374
Frontiers in endocrinology 2022;13:1051374
Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.
Zhu Z, Wang X, Zhang W, Gong M, Zhang S, Yang B, Qu B, Wu Z, Ma Q, Wang Z, Qian W
Frontiers in oncology 2022;12:960858
Frontiers in oncology 2022;12:960858
Mycoplasma hyopneumoniae Infection Activates the NOD1 Signaling Pathway to Modulate Inflammation.
Liu W, Jiang P, Yang K, Song Q, Yuan F, Liu Z, Gao T, Zhou D, Guo R, Li C, Sun P, Tian Y
Frontiers in cellular and infection microbiology 2022;12:927840
Frontiers in cellular and infection microbiology 2022;12:927840
Cathepsin B plays a role in spermatogenesis and sperm maturation through regulating autophagy and apoptosis in mice.
Wen Z, Zhu H, Wu B, Zhang A, Wang H, Cheng Y, Zhao H, Li J, Liu M, Gao J
PeerJ 2022;10:e14472
PeerJ 2022;10:e14472
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
Peng X, Yang R, Peng W, Zhao Z, Tu G, He B, Cai Q, Shi S, Yin W, Yu F, Tao Y, Wang X
PeerJ 2022;10:e14180
PeerJ 2022;10:e14180
CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.
Yang Y, Hong S, Lu Y, Wang Q, Wang S, Xun Y
PeerJ 2022;10:e14033
PeerJ 2022;10:e14033
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Zhang L, Li C, Fu L, Yu Z, Xu G, Zhou J, Shen M, Feng Z, Zhu H, Xie T, Zhou L, Zhou X
PeerJ 2022;10:e12759
PeerJ 2022;10:e12759
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515
Frontiers in bioengineering and biotechnology 2022;10:860515
Comprehensive Analysis of Quantitative Proteomics With DIA Mass Spectrometry and ceRNA Network in Intrahepatic Cholestasis of Pregnancy.
Fang D, Fang Y, Zhang W, Xiang Y, Cheng X, Liang M, Xia H
Frontiers in cell and developmental biology 2022;10:854425
Frontiers in cell and developmental biology 2022;10:854425
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Peng X, Ding C, Zhao Y, Hao M, Liu W, Yang M, Xiao F, Zheng Y
Frontiers in bioengineering and biotechnology 2022;10:831007
Frontiers in bioengineering and biotechnology 2022;10:831007
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Li W, Wang X, Liu T, Zhang Q, Cao J, Jiang Y, Sun Q, Li C, Wang W, Wang Y
Frontiers in cell and developmental biology 2022;10:813370
Frontiers in cell and developmental biology 2022;10:813370
Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy.
Lu J, Li R, Ni S, Xie Y, Liu X, Zhang K, Li Y
Frontiers in bioengineering and biotechnology 2022;10:1002291
Frontiers in bioengineering and biotechnology 2022;10:1002291
Ferulic acid ameliorates acetaminophen-induced acute liver injury by promoting AMPK-mediated protective autophagy.
Wu J, Zhou F, Fan G, Liu J, Wang Y, Xue X, Lyu X, Lin S, Li X
IUBMB life 2022 Sep;74(9):880-895
IUBMB life 2022 Sep;74(9):880-895
Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway.
Chen R, Yang H, Song Y, Yu H, Zhang M, Rao W, Wang Y, Xiao X, Chen Q, He Q
Molecular genetics and genomics : MGG 2022 Sep;297(5):1277-1287
Molecular genetics and genomics : MGG 2022 Sep;297(5):1277-1287
Gold nanoparticles targeting the autophagy-lysosome system to combat the inflammation-compromised osteogenic potential of periodontal ligament stem cells: From mechanism to therapy.
Yin Y, Tian BM, Li X, Yu YC, Deng DK, Sun LJ, Qu HL, Wu RX, Xu XY, Sun HH, An Y, He XT, Chen FM
Biomaterials 2022 Sep;288:121743
Biomaterials 2022 Sep;288:121743
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
Jia Q, Yang R, Mehmood S, Li Y
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1591-1600
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1591-1600
Propofol inhibits the malignant development of osteosarcoma U2OS cells via AMPK/FΟΧO1-mediated autophagy.
Dai L, Li S, Li X, Jiang B
Oncology letters 2022 Sep;24(3):310
Oncology letters 2022 Sep;24(3):310
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis.
Gao Y, Ma K, Kang Y, Liu W, Liu X, Long X, Hayashi T, Hattori S, Mizuno K, Fujisaki H, Ikejima T
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Sep;1867(9):159181
Biochimica et biophysica acta. Molecular and cell biology of lipids 2022 Sep;1867(9):159181
Ferulic acid ameliorates renal injury via improving autophagy to inhibit inflammation in diabetic nephropathy mice.
Ma R, He Y, Fang Q, Xie G, Qi M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113424
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113424
Long non-coding RNA IGFBP7-AS1 promotes odontogenic differentiation of stem cells from human exfoliated deciduous teeth through autophagy: An in vitro study.
Wang D, Zhu N, Xie F, Qin M, Wang Y
Archives of oral biology 2022 Sep;141:105492
Archives of oral biology 2022 Sep;141:105492
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
Zhu M, Zhang Y, Pan J, Tong X, Zhang X, Hu X, Gong C
Fish & shellfish immunology 2022 Sep;128:148-156
Fish & shellfish immunology 2022 Sep;128:148-156
Sodium butyrate attenuates bovine mammary epithelial cell injury by inhibiting the formation of neutrophil extracellular traps.
Li Y, Liu J, Cui Y, Cao Y, Xu P, Kan X, Guo W, Fu S
International immunopharmacology 2022 Sep;110:109009
International immunopharmacology 2022 Sep;110:109009
Celastrol upregulated ATG7 triggers autophagy via targeting Nur77 in colorectal cancer.
Zhang W, Wu Z, Qi H, Chen L, Wang T, Mao X, Shi H, Chen H, Zhong M, Shi X, Wang X, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154280
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154280
Achyranthoside D (AD) improve intervertebral disc degeneration through affect the autophagy and the activation of PI3K/Akt/mTOR pathway.
Zhang C, Li Z, Li L, Li S, Yang L, Chen L, Zhang X, Yang S, Guo Y
Journal of orthopaedic surgery (Hong Kong) 2022 Sep-Dec;30(3):10225536221135474
Journal of orthopaedic surgery (Hong Kong) 2022 Sep-Dec;30(3):10225536221135474
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway.
Fan Y, Lu J, Yu Z, Qu X, Guan S
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10847-10857
Journal of agricultural and food chemistry 2022 Sep 7;70(35):10847-10857
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Cai X, Hua S, Deng J, Du Z, Zhang D, Liu Z, Khan NU, Zhou M, Chen Z
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
2-Deoxy-D-glucose Alleviates Cancer Cachexia-Induced Muscle Wasting by Enhancing Ketone Metabolism and Inhibiting the Cori Cycle.
Wei L, Wang R, Wazir J, Lin K, Song S, Li L, Pu W, Zhao C, Wang Y, Su Z, Wang H
Cells 2022 Sep 25;11(19)
Cells 2022 Sep 25;11(19)
Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis.
Chou HC, Lin SY, Chou LY, Ho ML, Chuang SC, Cheng TL, Kang L, Lin YS, Wang YH, Wei CW, Chen CH, Wang CZ
Biomedicines 2022 Sep 2;10(9)
Biomedicines 2022 Sep 2;10(9)
Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway.
Lin Y, Zhang Q, Xie B, Jiang H, Shen J, Tang S, Dai C
Antioxidants (Basel, Switzerland) 2022 Sep 18;11(9)
Antioxidants (Basel, Switzerland) 2022 Sep 18;11(9)
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Ji J, Li S, Jiang Z, Yu J, Sun Y, Cai Z, Dong Y, Sun X
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy.
Wang M, Liu K, Bu H, Cong H, Dong G, Xu N, Li C, Zhao Y, Jiang F, Zhang Y, Yuan B, Li R, Jiang J
Molecular therapy oncolytics 2022 Sep 15;26:314-329
Molecular therapy oncolytics 2022 Sep 15;26:314-329
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
Nature communications 2022 Sep 12;13(1):5351
Nature communications 2022 Sep 12;13(1):5351
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
Wang H, Liang Z, Gou Y, Li Z, Cao Y, Jiao N, Tan J, Yu Y, Zhang Z
Cellular signalling 2022 Oct;98:110406
Cellular signalling 2022 Oct;98:110406
Puerarin prevents calcium oxalate crystal-induced renal epithelial cell autophagy by activating the SIRT1-mediated signaling pathway.
Jing GH, Liu YD, Liu JN, Jin YS, Yu SL, An RH
Urolithiasis 2022 Oct;50(5):545-556
Urolithiasis 2022 Oct;50(5):545-556
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
ROS function as an inducer of autophagy to promote granulocyte proliferation in Pacific oyster Crassostrea gigas.
Zhang D, Dong M, Song X, Qiao X, Yang Y, Yu S, Sun W, Wang L, Song L
Developmental and comparative immunology 2022 Oct;135:104479
Developmental and comparative immunology 2022 Oct;135:104479
CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1.
Song W, Zeng Z, Zhang Y, Li H, Cheng H, Wang J, Wu F
Cell death & disease 2022 Oct 8;13(10):857
Cell death & disease 2022 Oct 8;13(10):857
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Wang R, Shang Y, Chen B, Xu F, Zhang J, Zhang Z, Zhao X, Wan X, Xu A, Wu L, Zhao G
Cell death & disease 2022 Oct 6;13(10):851
Cell death & disease 2022 Oct 6;13(10):851
Haizao Yuhu decoctions including three species of glycyrrhiza protected against propylthiouracil-induced goiter with hypothyroidism in rats via the AMPK/mTOR pathway.
Li N, Li M, Xiu L, Liao W, Ren Y, Liu H, Chen S, Chen F, Yu X, Fan A, Huo M, He J, Zhong G
Journal of ethnopharmacology 2022 Oct 5;296:115443
Journal of ethnopharmacology 2022 Oct 5;296:115443
Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
Hou W, Chen M, Ye C, Chen E, Li W, Zhang W
Biomolecules 2022 Oct 31;12(11)
Biomolecules 2022 Oct 31;12(11)
Nobiletin mitigates NAFLD via lipophagy and inflammation.
Yang X, Deng Y, Tu Y, Feng D, Liao W
Food & function 2022 Oct 3;13(19):10186-10199
Food & function 2022 Oct 3;13(19):10186-10199
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Ba T, Zhao D, Chen Y, Zeng C, Zhang C, Niu S, Dai H
Nutrients 2022 Oct 28;14(21)
Nutrients 2022 Oct 28;14(21)
The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.
Li Q, Chu Y, Li S, Yu L, Deng H, Liao C, Liao X, Yang C, Qi M, Cheng J, Chen G, Huang L
Cell death & disease 2022 Oct 26;13(10):899
Cell death & disease 2022 Oct 26;13(10):899
Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.
Xie X, Hu L, Mi B, Xue H, Hu Y, Panayi AC, Endo Y, Chen L, Yan C, Lin Z, Li H, Zhou W, Liu G
Cell communication and signaling : CCS 2022 Oct 25;20(1):165
Cell communication and signaling : CCS 2022 Oct 25;20(1):165
MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.
Lv Z, Qiu X, Jin P, Li Z, Zhang Y, Lv L, Song F
Life (Basel, Switzerland) 2022 Oct 20;12(10)
Life (Basel, Switzerland) 2022 Oct 20;12(10)
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Zhan Y, Zhang Z, Liu Y, Fang Y, Xie Y, Zheng Y, Li G, Liang L, Ding Y
BMC medicine 2022 Oct 19;20(1):365
BMC medicine 2022 Oct 19;20(1):365
Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy.
Fan W, Ding C, Liu S, Gao X, Shen X, De Boevre M, Gao Z, Li M, Zhang S, Miao Y, Guan W, Liu G, Yan L, De Saeger S, Song S
Cell reports 2022 Oct 11;41(2):111454
Cell reports 2022 Oct 11;41(2):111454
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Zheng H, Liu Q, Wang S, Liu X, Ma M, Shen T, Wang X, Ren D
Chemico-biological interactions 2022 Oct 1;366:110125
Chemico-biological interactions 2022 Oct 1;366:110125
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.
Huang L, Chen Y, Liu R, Li B, Fei X, Li X, Liu G, Li Y, Xu B, Fang W
Aging and disease 2022 Oct 1;13(5):1546-1561
Aging and disease 2022 Oct 1;13(5):1546-1561
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Zhou Z, Dong Y, Li N, Niu M, Wang S, Zhou Y, Sun Z, Chu P, Tang Z
Cell biology international 2022 Nov;46(11):1801-1813
Cell biology international 2022 Nov;46(11):1801-1813
Rab11a promotes the malignant progression of ovarian cancer by inducing autophagy.
Wang Y, Ren Y, Li N, Zhao J, Zhao S
Genes & genomics 2022 Nov;44(11):1375-1384
Genes & genomics 2022 Nov;44(11):1375-1384
Tp47 promoted the phagocytosis of HMC3 cells though autophagy induced by endoplamic reticlum stress.
Li W, Li QL, Xu QY, Wang XT, Yang TC
Journal of the European Academy of Dermatology and Venereology : JEADV 2022 Nov;36(11):2224-2234
Journal of the European Academy of Dermatology and Venereology : JEADV 2022 Nov;36(11):2224-2234
Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation.
Wang H, Wu T, Huang Z, Huang J, Geng Z, Cui B, Yan Y, Zhang Y, Wang Y
The Journal of biological chemistry 2022 Nov;298(11):102599
The Journal of biological chemistry 2022 Nov;298(11):102599
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Xiao H, Peng L, Jiang D, Liu Y, Zhu L, Li Z, Geng J, Xie B, Huang X, Wang J, Dai H, Wang C
Journal of cellular and molecular medicine 2022 Nov;26(22):5728-5741
Journal of cellular and molecular medicine 2022 Nov;26(22):5728-5741
Effect of rapamycin treatment on oocyte in vitro maturation and embryonic development after parthenogenesis in yaks.
Zhang T, Wang L, Pan Y, He H, Wang J, Zhao T, Ding T, Wang Y, Zhao L, Han X, Fan J, Xu G, Cui Y, Yu S
Theriogenology 2022 Nov;193:128-135
Theriogenology 2022 Nov;193:128-135
Effects of ferulic acid, a major component of rice bran, on proliferation, apoptosis, and autophagy of HepG2 cells.
Wang J, Lai X, Yuan D, Liu Y, Wang J, Liang Y
Food research international (Ottawa, Ont.) 2022 Nov;161:111816
Food research international (Ottawa, Ont.) 2022 Nov;161:111816
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Zhou X, Li X, Yi K, Liang C, Geng S, Zhu J, Xie C, Zhong C
Bioorganic chemistry 2022 Nov;128:106034
Bioorganic chemistry 2022 Nov;128:106034
Paeoniflorin binds to VEGFR2 to restore autophagy and inhibit apoptosis for podocyte protection in diabetic kidney disease through PI3K-AKT signaling pathway.
Wang X, Jiang L, Liu XQ, Huang YB, Wang AL, Zeng HX, Gao L, Zhu QJ, Xia LL, Wu YG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154400
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Nov;106:154400
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Chen YH, Xu NZ, Hong C, Li WQ, Zhang YQ, Yu XY, Huang YL, Zhou JY
Cell death & disease 2022 Nov 8;13(11):939
Cell death & disease 2022 Nov 8;13(11):939
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Sen A, Kallabis S, Gaedke F, Jüngst C, Boix J, Nüchel J, Maliphol K, Hofmann J, Schauss AC, Krüger M, Wiesner RJ, Pla-Martín D
Nature communications 2022 Nov 7;13(1):6704
Nature communications 2022 Nov 7;13(1):6704
Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.
Ding Y, Xu Y, Fu Y, Zhang H, Zhao L, Fan X
Discover oncology 2022 Nov 6;13(1):121
Discover oncology 2022 Nov 6;13(1):121
Long-Term Consumption of Food-Derived Chlorogenic Acid Protects Mice against Acetaminophen-Induced Hepatotoxicity via Promoting PINK1-Dependent Mitophagy and Inhibiting Apoptosis.
Hu B, Li J, Gong D, Dai Y, Wang P, Wan L, Xu S
Toxics 2022 Nov 5;10(11)
Toxics 2022 Nov 5;10(11)
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Autophagy Is a Crucial Path in Chondrogenesis of Adipose-Derived Mesenchymal Stromal Cells Laden in Hydrogel.
Gabusi E, Lenzi E, Manferdini C, Dolzani P, Columbaro M, Saleh Y, Lisignoli G
Gels (Basel, Switzerland) 2022 Nov 24;8(12)
Gels (Basel, Switzerland) 2022 Nov 24;8(12)
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Cao Y, Zhang M, Li Y, Lu J, Zhou W, Li X, Shi H, Xu B, Li S
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
Moderate Treadmill Exercise Alleviates NAFLD by Regulating the Biogenesis and Autophagy of Lipid Droplet.
Yang Y, Li X, Liu Z, Ruan X, Wang H, Zhang Q, Cao L, Song L, Chen Y, Sun Y
Nutrients 2022 Nov 20;14(22)
Nutrients 2022 Nov 20;14(22)
Trpc5-regulated AMPKα/mTOR autophagy pathway is associated with glucose metabolism disorders in low birth weight mice under overnutrition.
Zhou F, Yang L, Yang L, Wang X, Guo N, Sun W, Ma H
Biochemical and biophysical research communications 2022 Nov 19;630:1-7
Biochemical and biophysical research communications 2022 Nov 19;630:1-7
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
Pan Z, Chen Y, Pang H, Wang X, Zhang Y, Xie X, He G
European journal of medicinal chemistry 2022 Nov 15;242:114674
European journal of medicinal chemistry 2022 Nov 15;242:114674
Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance.
Wang C, Li Z, Xu P, Xu L, Han S, Sun Y
Journal of nanobiotechnology 2022 Nov 11;20(1):476
Journal of nanobiotechnology 2022 Nov 11;20(1):476
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Liu J, Li D, Dun Y, Li H, Ripley-Gonzalez JW, Zhang J, Qiu L, You B, Liu S
Life sciences 2022 Nov 1;308:120949
Life sciences 2022 Nov 1;308:120949
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
Dihydromyricetin protects against Doxorubicin-induced cardiotoxicity through activation of AMPK/mTOR pathway.
Li X, Wang X, Wang B, Chi W, Li Z, Zhang M, Shen Y, Liu X, Lu Y, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154027
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154027
MiR-1298-5p level downregulation induced by Helicobacter pylori infection inhibits autophagy and promotes gastric cancer development by targeting MAP2K6.
Li X, Zhu M, Zhao G, Zhou A, Min L, Liu S, Zhang N, Zhu S, Guo Q, Zhang S, Li P
Cellular signalling 2022 May;93:110286
Cellular signalling 2022 May;93:110286
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Guo L, Jiang ZM, Sun RX, Pang W, Zhou X, Du ML, Chen MX, Lv X, Wang JT
Brain research bulletin 2022 May;182:111-117
Brain research bulletin 2022 May;182:111-117
Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.
Dai C, Li M, Sun T, Zhang Y, Wang Y, Shen Z, Velkov T, Tang S, Shen J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 May;163:112966
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 May;163:112966
Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.
Xu S, Xia X, Liu Y, Chen F, Gu R, Bian X, Xu X, Jia C, Lu S, Gu Y, Bai H, Zhang H
Microvascular research 2022 May;141:104313
Microvascular research 2022 May;141:104313
Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1/Parkin pathway in rats.
Zhang D, Zheng N, Fu X, Shi J, Zhang J
Journal of thoracic disease 2022 May;14(5):1651-1662
Journal of thoracic disease 2022 May;14(5):1651-1662
Paired related homeobox 1 attenuates autophagy via acetyl-CoA carboxylase 1-regulated fatty acid metabolism in salivary adenoid cystic carcinoma.
Gao J, Ma K, Zhang L, Li T, Zhao B, Jiang Y
FEBS open bio 2022 May;12(5):1006-1016
FEBS open bio 2022 May;12(5):1006-1016
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Dong S, Kong N, Zhang Y, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 May 25;96(10):e0007022
Journal of virology 2022 May 25;96(10):e0007022
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Meng Z, Zhu B, Gao M, Wang G, Zhou H, Lu J, Guan S
Food & function 2022 May 23;13(10):5559-5570
Food & function 2022 May 23;13(10):5559-5570
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
Wei L, Ma W, Cai H, Peng SP, Tian HB, Wang JF, Gao L, He JP
Biomedical and environmental sciences : BES 2022 May 20;35(5):419-436
Biomedical and environmental sciences : BES 2022 May 20;35(5):419-436
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
Yang J, Li J, Guo H, Zhang Y, Guo Z, Liu Y, Huo T
International journal of molecular sciences 2022 May 19;23(10)
International journal of molecular sciences 2022 May 19;23(10)
TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.
Tang H, Huang H, Wang D, Li P, Tian Z, Li D, Wang S, Ma R, Xia T, Wang A
Journal of hazardous materials 2022 May 15;430:128483
Journal of hazardous materials 2022 May 15;430:128483
Quercus acutissima Carruth. root extract triggers apoptosis, autophagy and inhibits cell viability in breast cancer cells.
Ding W, Chen C, Li J, Geng X, Zhang H, Sun Y
Journal of ethnopharmacology 2022 May 10;289:115039
Journal of ethnopharmacology 2022 May 10;289:115039
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Chen D, Jiang X
Experimental cell research 2022 May 1;414(1):113066
Experimental cell research 2022 May 1;414(1):113066
sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes.
Zhu L, Li B, Chen D, Chen N, Xu L, Li Q, Chen X
Life sciences 2022 May 1;296:120438
Life sciences 2022 May 1;296:120438
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Han X, Tang Y, Zhang Y, Zhang J, Hu Z, Xu W, Xu S, Niu Q
Ecotoxicology and environmental safety 2022 May 1;236:113500
Ecotoxicology and environmental safety 2022 May 1;236:113500
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Deng CY, Zhu TT, Lian S, Wang JF, Wu R, Zheng JS
Journal of veterinary research 2022 Mar;66(1):131-140
Journal of veterinary research 2022 Mar;66(1):131-140
Evaluation of BPA effects on autophagy in Neuro-2a cells.
Li J, Yin Z, Hua L, Wang X, Ren F, Ge Y
Toxicology and industrial health 2022 Mar;38(3):151-161
Toxicology and industrial health 2022 Mar;38(3):151-161
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2022 Mar;37(3):549-563
Environmental toxicology 2022 Mar;37(3):549-563
CN-3 increases TMZ sensitivity and induces ROS-dependent apoptosis and autophagy in TMZ-resistance glioblastoma.
Xue YY, Lu YY, Sun GQ, Fang F, Ji YQ, Tang HF, Qiu PC, Cheng G
Journal of biochemical and molecular toxicology 2022 Mar;36(3):e22973
Journal of biochemical and molecular toxicology 2022 Mar;36(3):e22973
Vitamin D3 promotes autophagy in THP-1 cells infected with Mycobacterium tuberculosis.
Wu Y, Lin X, Song F, Xue D, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):240
Experimental and therapeutic medicine 2022 Mar;23(3):240
miR-146a-5p/TXNIP axis attenuates intestinal ischemia-reperfusion injury by inhibiting autophagy via the PRKAA/mTOR signaling pathway.
Zhenzhen L, Wenting L, Jianmin Z, Guangru Z, Disheng L, Zhiyu Z, Feng C, Yajing S, Yingxiang H, Jipeng L, Zhanhai W, Yan Z, Xin L, Yongqiang L, Yufang L
Biochemical pharmacology 2022 Mar;197:114839
Biochemical pharmacology 2022 Mar;197:114839
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Ren X, Lv J, Wang N, Liu J, Gao C, Wu X, Yu Y, Teng Q, Dong W, Kong H, Kong L
Diabetes research and clinical practice 2022 Mar;185:109788
Diabetes research and clinical practice 2022 Mar;185:109788
MiR-7-5p suppresses invasion via downregulation of the autophagy-related gene ATG7 and increases chemoresistance to cisplatin in BCa.
Wang C, Tang Z, Zhang Z, Liu T, Zhang J, Huang H, Li Y
Bioengineered 2022 Mar;13(3):7328-7339
Bioengineered 2022 Mar;13(3):7328-7339
Bcl-2 interacting protein 3 (BNIP3) promotes tumor growth in breast cancer under hypoxic conditions through an autophagy-dependent pathway.
Zhang G, Xu Z, Yu M, Gao H
Bioengineered 2022 Mar;13(3):6280-6292
Bioengineered 2022 Mar;13(3):6280-6292
Chicoric Acid Attenuated Renal Tubular Injury in HFD-Induced Chronic Kidney Disease Mice through the Promotion of Mitophagy via the Nrf2/PINK/Parkin Pathway.
Ding XQ, Jian TY, Gai YN, Niu GT, Liu Y, Meng XH, Li J, Lyu H, Ren BR, Chen J
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2923-2935
Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.
Xu Z, Zhang M, Li X, Wang Y, Du R
International journal of molecular sciences 2022 Mar 30;23(7)
International journal of molecular sciences 2022 Mar 30;23(7)
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
Gu X, Zhang L, Sun W, Liu K, Xu H, Wu P, Gui M, Qu W
Chemical research in toxicology 2022 Mar 21;35(3):392-401
Chemical research in toxicology 2022 Mar 21;35(3):392-401
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Guan X, Yan Q, Wang D, Du G, Zhou J
Nutrients 2022 Mar 16;14(6)
Nutrients 2022 Mar 16;14(6)
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
Ye N, Lv Z, Huang Z, Cheng Y, Wei Q, Shi F
Theriogenology 2022 Mar 15;181:8-15
Theriogenology 2022 Mar 15;181:8-15
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
He Z, Cai K, Zeng Z, Lei S, Cao W, Li X
Cell death & disease 2022 Mar 14;13(3):233
Cell death & disease 2022 Mar 14;13(3):233
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Zhong Y, Sun D, Yao Y, Liu Q, Guo T, Wang X, Peng X
Chemico-biological interactions 2022 Mar 1;355:109850
Chemico-biological interactions 2022 Mar 1;355:109850
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.
Ouyang S, Li H, Lou L, Huang Q, Zhang Z, Mo J, Li M, Lu J, Zhu K, Chu Y, Ding W, Zhu J, Lin Z, Zhong L, Wang J, Yue P, Turkson J, Liu P, Wang Y, Zhang X
Redox biology 2022 Jun;52:102317
Redox biology 2022 Jun;52:102317
Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cells.
Sun S, Li Z, Huan S, Kai J, Xia S, Su Y, Ji S, Chen A, Wang S, Xu X, Shao J, Zhang F, Zhang B, Zhang Z, Zheng S
Phytotherapy research : PTR 2022 Jun;36(6):2660-2676
Phytotherapy research : PTR 2022 Jun;36(6):2660-2676
Genome-wide CRISPR/Cas9 screen identifies host factors important for porcine reproductive and respiratory syndrome virus replication.
Jiang J, Sun Y, Wang Y, Sabek A, Shangguan A, Wang K, Zhao S, Li G, Zhou A, Zhang S
Virus research 2022 Jun;314:198738
Virus research 2022 Jun;314:198738
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Ren K, He J, Qiu Y, Xu Z, Wang X, Li J, Zang S, Yang Y, Li J, Long Y, Zhang Z, Li M, He Q
Acta biomaterialia 2022 Jun;145:185-199
Acta biomaterialia 2022 Jun;145:185-199
CXCR4 inhibition attenuates calcium oxalate crystal deposition-induced renal fibrosis.
Ye Z, Xia Y, Zhou X, Li B, Yu W, Ruan Y, Li H, Ning J, Chen L, Rao T, Cheng F
International immunopharmacology 2022 Jun;107:108677
International immunopharmacology 2022 Jun;107:108677
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Gao A, Zou J, Mao Z, Zhou H, Zeng G
European journal of pharmacology 2022 Jun 5;924:174980
European journal of pharmacology 2022 Jun 5;924:174980
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Zhang B, Ma Y, Niu H, Liu Z
Biochemical and biophysical research communications 2022 Jun 4;607:81-88
Biochemical and biophysical research communications 2022 Jun 4;607:81-88
Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma.
Yan W, Shi X, Wang H, Liao A, Yang W
Journal of translational medicine 2022 Jun 30;20(1):296
Journal of translational medicine 2022 Jun 30;20(1):296
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278
Stem cell research & therapy 2022 Jun 28;13(1):278
Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat.
Wang M, Qi Y, Cao Y, Zhang X, Wang Y, Liu Q, Zhang J, Zhou G, Ai Y, Wei S, Wang L, Liu G, Lian Z, Han H
eLife 2022 Jun 28;11
eLife 2022 Jun 28;11
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.
Chen Z, Wang H, Hu B, Chen X, Zheng M, Liang L, Lyu J, Zeng Q
European journal of histochemistry : EJH 2022 Jun 21;66(3)
European journal of histochemistry : EJH 2022 Jun 21;66(3)
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis.
Deng R, Wang Y, Bu Y, Wu H
Molecular medicine (Cambridge, Mass.) 2022 Jun 11;28(1):64
Molecular medicine (Cambridge, Mass.) 2022 Jun 11;28(1):64
Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids.
Ni Y, Hu Y, Lou X, Rong N, Liu F, Yang C, Zheng A, Yang S, Bao J, Fu Z
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6478-6492
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6478-6492
Clinical, genetic, and pathological characterization of GNE myopathy in China.
Lv XQ, Xu L, Lin PF, Yan CZ
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2022 Jul;43(7):4483-4491
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2022 Jul;43(7):4483-4491
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy.
Dong J, Zhang KJ, Li GC, Chen XR, Lin JJ, Li JW, Lv ZY, Deng ZZ, Dai J, Cao W, Jiang Q
Acta pharmacologica Sinica 2022 Jul;43(7):1793-1802
Acta pharmacologica Sinica 2022 Jul;43(7):1793-1802
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Wang J, Wang Q, Chen P, Li Q, Li Z, Xu M, Zeng K, Li C
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure.
Wang H, Zhou Y, Xu C, Cao Y, Xiao Y, Cai D, Uemoto Y, Wu S, Bao W
Chemosphere 2022 Jul;298:134199
Chemosphere 2022 Jul;298:134199
Autism spectrum disorder-like behavior induced in rat offspring by perinatal exposure to di-(2-ethylhexyl) phthalate.
Li Y, Zhao Y, Lu Y, Lu X, Hu Y, Li Q, Shuai M, Li R
Environmental science and pollution research international 2022 Jul;29(34):52083-52097
Environmental science and pollution research international 2022 Jul;29(34):52083-52097
The cardiotoxicity of asthmatic rats after traffic-related PM(2.5) and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy.
Tian J, Shi H, Wang X, Wu H, Wang C, Liu N, Wang D, Shi D, Zhang H, Zhang Z
Environmental science and pollution research international 2022 Jul;29(33):50704-50716
Environmental science and pollution research international 2022 Jul;29(33):50704-50716
TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy.
Tian W, Liu SY, Zhang M, Meng JR, Tang N, Feng YD, Sun Y, Gao YY, Zhou L, Cao W, Li XQ
Pharmacological research 2022 Jul;181:106262
Pharmacological research 2022 Jul;181:106262
Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy.
Liu Y, Wei CH, Li C, Chen WZ, Zhu Y, Xu RS
Neural regeneration research 2022 Jul;17(7):1609-1616
Neural regeneration research 2022 Jul;17(7):1609-1616
Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy.
Jin Z, Chang B, Wei Y, Yang Y, Zhang H, Liu J, Piao L, Bai L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113092
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113092
3,4,5-O-tricaffeoylquinic acid with anti-radiation activity suppresses LPS-induced NLRP3 inflammasome activation via autophagy in THP-1 macrophages.
Liu J, Chen J, Xu B, Lin L, Liu S, Ma X, Liu J
Molecular immunology 2022 Jul;147:187-198
Molecular immunology 2022 Jul;147:187-198
Multifunctional theranostic nanoplatform loaded with autophagy inhibitor for enhanced photothermal cancer therapy under mild near-infrared irradiation.
Shi M, Liu Y, Huang J, Chen Z, Ni C, Lu J, Zhang Y, Liu Z, Bai J
Biomaterials advances 2022 Jul;138:212919
Biomaterials advances 2022 Jul;138:212919
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Cao J, Chen C, Chen Q, Gao Y, Zhao Z, Yuan Q, Li A, Yang S, He Y, Zu X, Liu J
Journal of translational medicine 2022 Jul 6;20(1):307
Journal of translational medicine 2022 Jul 6;20(1):307
Resveratrol alleviates enterotoxigenic Escherichia coli K88-induced damage by regulating SIRT-1 signaling in intestinal porcine epithelial cells.
Luo X, Wu S, Jia H, Si X, Song Z, Zhai Z, Bai J, Li J, Yang Y, Wu Z
Food & function 2022 Jul 4;13(13):7346-7360
Food & function 2022 Jul 4;13(13):7346-7360
Gga-miR-30c-5p Suppresses Avian Reovirus (ARV) Replication by Inhibition of ARV-Induced Autophagy via Targeting ATG5.
Zhou L, Haiyilati A, Li J, Li X, Gao L, Cao H, Wang Y, Zheng SJ
Journal of virology 2022 Jul 27;96(14):e0075922
Journal of virology 2022 Jul 27;96(14):e0075922
MiR-152-5p suppresses osteogenic differentiation of mandible mesenchymal stem cells by regulating ATG14-mediated autophagy.
Li S, Gao L, Zhang W, Yu Y, Zheng J, Liang X, Xin S, Ren W, Zhi K
Stem cell research & therapy 2022 Jul 26;13(1):359
Stem cell research & therapy 2022 Jul 26;13(1):359
T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells.
Sun T, Zhang Q, Li M, Tang S, Dai C
Journal of fungi (Basel, Switzerland) 2022 Jul 22;8(8)
Journal of fungi (Basel, Switzerland) 2022 Jul 22;8(8)
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis.
Jin J, Qiao S, Liu J, Li W, Wang F, Gao X, Tian J, Wang N, Zhang J, Dong J, Li H, Wang J, Hu S, Zhou P
Cell & bioscience 2022 Jul 22;12(1):114
Cell & bioscience 2022 Jul 22;12(1):114
FUNDC1-mediated mitophagy and HIF1α activation drives pulmonary hypertension during hypoxia.
Liu R, Xu C, Zhang W, Cao Y, Ye J, Li B, Jia S, Weng L, Liu Y, Liu L, Zheng M
Cell death & disease 2022 Jul 21;13(7):634
Cell death & disease 2022 Jul 21;13(7):634
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Zhong X, Wu Q, Wang Z, Zhang M, Zheng S, Shi F, Chen Y, Che Y, Yuan S, Xing K
Food & function 2022 Jul 18;13(14):7666-7683
Food & function 2022 Jul 18;13(14):7666-7683
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Tan J, Xu T, Gou Y, Wang H, Liang Z, Cao Y, Wang H, Yu Y, Jiao N, Zhang Z
Stem cell research & therapy 2022 Jul 15;13(1):294
Stem cell research & therapy 2022 Jul 15;13(1):294
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Dong S, Kong N, Wang C, Li Y, Sun D, Qin W, Zhai H, Zhai X, Yang X, Ye C, Ye M, Liu C, Yu L, Zheng H, Tong W, Yu H, Zhang W, Tong G, Shan T
Journal of virology 2022 Jul 13;96(13):e0061822
Journal of virology 2022 Jul 13;96(13):e0061822
Rosa rugosa polysaccharide induces autophagy-mediated apoptosis in human cervical cancer cells via the PI3K/AKT/mTOR pathway.
Liu Y, Li H, Zheng Z, Niu A, Liu S, Li W, Ren P, Liu Y, Inam M, Guan L, Ma H
International journal of biological macromolecules 2022 Jul 1;212:257-274
International journal of biological macromolecules 2022 Jul 1;212:257-274
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma.
Xu Q, Zhang H, Liu H, Han Y, Qiu W, Li Z
Biomaterials 2022 Jan;280:121287
Biomaterials 2022 Jan;280:121287
Lycorine improves peripheral nerve function by promoting Schwann cell autophagy via AMPK pathway activation and MMP9 downregulation in diabetic peripheral neuropathy.
Yuan Q, Zhang X, Wei W, Zhao J, Wu Y, Zhao S, Zhu L, Wang P, Hao J
Pharmacological research 2022 Jan;175:105985
Pharmacological research 2022 Jan;175:105985
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Zhou YH, Tang YZ, Guo LY, Zheng LL, Zhang D, Yang CY, Wang W
Microvascular research 2022 Jan;139:104252
Microvascular research 2022 Jan;139:104252
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy.
Wu H, Li G, Chen W, Luo W, Yang Z, You Z, Zou Y
Acta histochemica 2022 Jan;124(1):151837
Acta histochemica 2022 Jan;124(1):151837
Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma.
Zhuang A, Chai P, Wang S, Zuo S, Yu J, Jia S, Ge S, Jia R, Zhou Y, Shi W, Xu X, Ruan J, Fan X
Clinical and translational medicine 2022 Jan;12(1):e660
Clinical and translational medicine 2022 Jan;12(1):e660
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Nie BX, Zhao G, Yuan XF, Yu LX, Zhang J, Yuan Y, Liu Y, Hu J, Song E, Zhou YC, Shu J
Journal of chemical neuroanatomy 2022 Jan;119:102053
Journal of chemical neuroanatomy 2022 Jan;119:102053
Imiquimod induced vitiligo-like lesions-A consequence of modified melanocyte function.
Yu H, Cen J, Lin X, Cheng H, Seifert O
Immunity, inflammation and disease 2022 Jan;10(1):70-77
Immunity, inflammation and disease 2022 Jan;10(1):70-77
Mitochondrial dysfunction is involved in the cellular activity inhibition by eleutheroside B in SMMC-7721 and HeLa cells.
Sun S, Zhang Y, Xu W, Wang B, Chen J
Human & experimental toxicology 2022 Jan-Dec;41:9603271221089006
Human & experimental toxicology 2022 Jan-Dec;41:9603271221089006
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Zhang P, Zhang J, Quan H, Chen P, Wang J, Liang Y
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Human & experimental toxicology 2022 Jan-Dec;41:9603271221074346
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
Zheng LY, Zou X, Wang YL, Zou M, Ma F, Wang N, Li JW, Wang MS, Hung HY, Wang Q
European journal of pharmacology 2022 Jan 5;914:174686
European journal of pharmacology 2022 Jan 5;914:174686
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Yang L, Wang Q, Zhao Q, Yang F, Liu T, Huang X, Yan Q, Yang X
Aging 2022 Jan 4;14(1):316-329
Aging 2022 Jan 4;14(1):316-329
Host Restriction Factor A3G Inhibits the Replication of Enterovirus D68 by Competitively Binding the 5' Untranslated Region with PCBP1.
Li Z, Yang X, Zhao Z, Liu X, Zhang W
Journal of virology 2022 Jan 26;96(2):e0170821
Journal of virology 2022 Jan 26;96(2):e0170821
Structural Variability of Lipoarabinomannan Modulates Innate Immune Responses within Infected Alveolar Epithelial Cells.
Liu H, Gui X, Chen S, Fu W, Li X, Xiao T, Hou J, Jiang T
Cells 2022 Jan 21;11(3)
Cells 2022 Jan 21;11(3)
Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway.
Liu P, Wu A, Li H, Zhang J, Ni J, Quan Z, Qing H
International journal of molecular sciences 2022 Jan 20;23(3)
International journal of molecular sciences 2022 Jan 20;23(3)
C9orf72 knockdown alleviates hepatic insulin resistance by promoting lipophagy.
Cang X, Wang Y, Zeng J, Gao J, Yu Q, Lu C, Xu F, Lin J, Zhu J, Wang X
Biochemical and biophysical research communications 2022 Jan 15;588:15-22
Biochemical and biophysical research communications 2022 Jan 15;588:15-22
Biotinylated curcumin as a novel chemosensitizer enhances naphthalimide-induced autophagic cell death in breast cancer cells.
Shao C, Wu J, Han S, Liu Y, Su Z, Zhu HL, Liu HK, Qian Y
European journal of medicinal chemistry 2022 Jan 15;228:114029
European journal of medicinal chemistry 2022 Jan 15;228:114029
Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy.
Zhi W, Li S, Wan Y, Wu F, Hong L
Cancer cell international 2022 Jan 11;22(1):18
Cancer cell international 2022 Jan 11;22(1):18
RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.
Liu X, Chen J, Long X, Lan J, Liu X, Zhou M, Zhang S, Zhou J
Cell death & disease 2022 Jan 10;13(1):43
Cell death & disease 2022 Jan 10;13(1):43
Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis.
Wu J, Lin T, Gao Y, Li X, Yang C, Zhang K, Wang C, Zhou X
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Molecular and cellular endocrinology 2022 Jan 1;539:111490
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Wang P, Li CG, Zhou X, Ding S
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2022 Feb;49(2):1223-1232
Molecular biology reports 2022 Feb;49(2):1223-1232
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis.
Wen C, Lin L, Zou R, Lin F, Liu Y
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303
Cell cycle (Georgetown, Tex.) 2022 Feb;21(3):289-303
Visualizing the native cellular organization by coupling cryofixation with expansion microscopy (Cryo-ExM).
Laporte MH, Klena N, Hamel V, Guichard P
Nature methods 2022 Feb;19(2):216-222
Nature methods 2022 Feb;19(2):216-222
AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner.
Huang W, Li N, Zhang Y, Wang X, Yin M, Lei QY
Autophagy 2022 Feb;18(2):309-319
Autophagy 2022 Feb;18(2):309-319
Alliin alleviates LPS-induced pyroptosis via promoting mitophagy in THP-1 macrophages and mice.
Liu M, Lu J, Yang S, Chen Y, Yu J, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Feb;160:112811
Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis rats by inhibiting Th1/Th17 immune responses.
Zhu Q, Muyayalo KP, Xu QH, Wang J, Wang H, Liao AH
Journal of reproductive immunology 2022 Feb;149:103469
Journal of reproductive immunology 2022 Feb;149:103469
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
Liu Z, Yun B, Han Y, Jiang Z, Zhu H, Ren F, Li Z
Advanced healthcare materials 2022 Feb;11(3):e2102042
Advanced healthcare materials 2022 Feb;11(3):e2102042
Levosimendan protects from sepsis-inducing cardiac dysfunction by suppressing inflammation, oxidative stress and regulating cardiac mitophagy via the PINK-1-Parkin pathway in mice.
Shi J, Chen Y, Zhi H, An H, Hu Z
Annals of translational medicine 2022 Feb;10(4):212
Annals of translational medicine 2022 Feb;10(4):212
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice.
Packialakshmi B, Stewart IJ, Burmeister DM, Feng Y, McDaniel DP, Chung KK, Zhou X
Physiological reports 2022 Feb;10(3):e15181
Physiological reports 2022 Feb;10(3):e15181
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, Yang J, Zhang C, Jiang F
EMBO reports 2022 Feb 3;23(3):e53373
EMBO reports 2022 Feb 3;23(3):e53373
Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas.
Gao L, Zhang Q, Li S, Zheng J, Ren W, Zhi K
Cell death & disease 2022 Feb 26;13(2):192
Cell death & disease 2022 Feb 26;13(2):192
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
Yin J, Wang J, Zhang X, Liao Y, Luo W, Wang S, Ding J, Huang J, Chen M, Wang W, Fang S, Chao J
Cell & bioscience 2022 Feb 25;12(1):21
Cell & bioscience 2022 Feb 25;12(1):21
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
Wang Y, Xu J, Wang Y, Xiang L, He X
Food & function 2022 Feb 21;13(4):2200-2215
Food & function 2022 Feb 21;13(4):2200-2215
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162
Cell death & disease 2022 Feb 18;13(2):162
Tryptophan-sorbitol based carbon quantum dots for theranostics against hepatocellular carcinoma.
Wang Y, Chen J, Tian J, Wang G, Luo W, Huang Z, Huang Y, Li N, Guo M, Fan X
Journal of nanobiotechnology 2022 Feb 14;20(1):78
Journal of nanobiotechnology 2022 Feb 14;20(1):78
RNA sequence analysis reveals pathways and candidate genes associated with pancreatic acinar cells injury in a mouse pancreatitis model.
Chaoqun H, Rong Y, Yunpeng P, Xiaole Z, Wanli G, Chenyuan S, Dongya H, Yi M, Qiang L
Tissue & cell 2022 Dec;79:101940
Tissue & cell 2022 Dec;79:101940
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Bian Y, Xue M, Guo X, Jiang W, Zhao Y, Zhang Z, Wang X, Hu Y, Zhang Q, Dun W, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Pharmaceutical biology 2022 Dec;60(1):1801-1811
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
Jiao Y, Xin M, Xu J, Xiang X, Li X, Jiang J, Jia X
Pharmaceutical biology 2022 Dec;60(1):1781-1789
Pharmaceutical biology 2022 Dec;60(1):1781-1789
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
Li Z, Wu Z, Xi X, Zhao F, Liu H, Liu D
Journal of periodontal research 2022 Dec;57(6):1169-1182
Journal of periodontal research 2022 Dec;57(6):1169-1182
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
Zhou J, Tan Y, Hu L, Fu J, Li D, Chen J, Long Y
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2889-2899
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2889-2899
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Yao J, Wu J, Jia S, Shao J, Zhang X, Xu Z, Zhang H, Li H, Yao X
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793
Journal of clinical laboratory analysis 2022 Dec;36(12):e24793
LRPPRC inhibits autophagy and promotes foam cell formation in atherosclerosis.
Xu Z, Li X, Ding Z, Zhang Y, Peng Z, Yang X, Cao W, Du R
The FEBS journal 2022 Dec;289(23):7545-7560
The FEBS journal 2022 Dec;289(23):7545-7560
LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma.
Zang X, Wang J, Xia Y, Li J, Chen L, Gu Y, Shen X
Leukemia research 2022 Dec;123:106967
Leukemia research 2022 Dec;123:106967
The SMYD3-MTHFD1L-formate metabolic regulatory axis mediates mitophagy to inhibit M1 polarization in macrophages.
Zhu W, Wang C, Xue L, Liu L, Yang X, Liu Z, Zhang S, Luo D
International immunopharmacology 2022 Dec;113(Pt A):109352
International immunopharmacology 2022 Dec;113(Pt A):109352
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Meng Y, Qiu L, Zeng X, Hu X, Zhang Y, Wan X, Mao X, Wu J, Xu Y, Xiong Q, Chen Z, Zhang B, Han J
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Sulforaphane Ameliorates Hepatic Lipid Metabolism via Modulating Lipophagy In Vivo and In Vitro.
Lei P, Hu Y, Gao P, Ding Q, Yan J, Zhao J, Li B, Shan Y
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15126-15133
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15126-15133
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Yang Y, Li Y, Yang Q, Liu Z, Chang X, Yang H, Liu J, Li Z, Zuo D
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes 2022 Dec 27;14(1)
Genes 2022 Dec 27;14(1)
The selective NLRP3 inflammasome inhibitor MCC950 improves isoproterenol-induced cardiac dysfunction by inhibiting cardiomyocyte senescence.
Shi Y, Zhao L, Wang J, Liu S, Zhang Y, Qin Q
European journal of pharmacology 2022 Dec 15;937:175364
European journal of pharmacology 2022 Dec 15;937:175364
HIF-1α-mediated autophagy and canonical Wnt/β-catenin signalling activation are involved in fluoride-induced osteosclerosis in rats.
Zhu S, Liu J, Zhao J, Zhou B, Zhang Y, Wang H
Environmental pollution (Barking, Essex : 1987) 2022 Dec 15;315:120396
Environmental pollution (Barking, Essex : 1987) 2022 Dec 15;315:120396
Lactoferrin alleviates spermatogenesis dysfunction caused by bisphenol A and cadmium via ameliorating disordered autophagy, apoptosis and oxidative stress.
He H, Chen X, Li X, Yang K, Li J, Shi H
International journal of biological macromolecules 2022 Dec 1;222(Pt A):1048-1062
International journal of biological macromolecules 2022 Dec 1;222(Pt A):1048-1062
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Yang F, Peng ZX, Ji WD, Yu JD, Qian C, Liu JD, Fang GE
Digestive diseases and sciences 2022 Aug;67(8):3725-3741
Digestive diseases and sciences 2022 Aug;67(8):3725-3741
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress.
Liang L, Wang H, Hu Y, Bian H, Xiao L, Wang G
Phytotherapy research : PTR 2022 Aug;36(8):3335-3351
Phytotherapy research : PTR 2022 Aug;36(8):3335-3351
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Li M, Wang C, Yu Z, Lan Q, Xu S, Ye Z, Li R, Ying L, Zhang X, Zhou Z
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505
Journal of cellular and molecular medicine 2022 Aug;26(16):4492-4505
Dietary supplementation with metformin improves testis function and semen quality and increases antioxidants and autophagy capacity in goats.
Zhao J, Yang PC, Yang H, Wang ZB, El-Samahy MA, Wang F, Zhang YL
Theriogenology 2022 Aug;188:79-89
Theriogenology 2022 Aug;188:79-89
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Ding Q, Chen K, Liu X, Ding C, Zhao Y, Sun S, Zhang Y, Zhang J, Liu S, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Inhibition of autophagy by 3-methyladenine promotes migration and invasion of colon cancer cells through epithelial mesenchymal transformation.
Zhang X, Wang H, Yu M, Ma K, Ning L
Translational cancer research 2022 Aug;11(8):2834-2842
Translational cancer research 2022 Aug;11(8):2834-2842
Comprehensive analysis of placental gene-expression profiles and identification of EGFR-mediated autophagy and ferroptosis suppression in intrahepatic cholestasis of pregnancy.
Fang Y, Fang D
Gene 2022 Aug 5;834:146594
Gene 2022 Aug 5;834:146594
CHST7 Methylation Status Related to the Proliferation and Differentiation of Pituitary Adenomas.
Dong W, Shi W, Liu Y, Li J, Zhang Y, Dong G, Dong X, Gao H
Cells 2022 Aug 4;11(15)
Cells 2022 Aug 4;11(15)
Hyaluronic Acid Oligosaccharide Derivatives Alleviate Lipopolysaccharide-Induced Inflammation in ATDC5 Cells by Multiple Mechanisms.
Huang H, Ding X, Xing D, Lin J, Li Z, Lin J
Molecules (Basel, Switzerland) 2022 Aug 31;27(17)
Molecules (Basel, Switzerland) 2022 Aug 31;27(17)
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Jia X, Xin M, Xu J, Xiang X, Li X, Jiao Y, Wang L, Jiang J, Pang F, Zhang X, Zhang J
Cell death & disease 2022 Aug 30;13(8):750
Cell death & disease 2022 Aug 30;13(8):750
Sesamin Ameliorates Fine Particulate Matter (PM(2.5))-Induced Lung Injury via Suppression of Apoptosis and Autophagy in Rats.
Ren J, Li X, Zhu S, Yin B, Guo Z, Cui Q, Song J, Pei H, Ma Y
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9489-9498
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9489-9498
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Hao X, Fan H, Yang J, Tang J, Zhou J, Zhao Y, Huang L, Xia Y
Journal of natural products 2022 Aug 26;85(8):2006-2017
Journal of natural products 2022 Aug 26;85(8):2006-2017
The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.
Li S, Gao L, Liu J, Guo C, Zheng J, Zhi K, Ren W
Cell death discovery 2022 Aug 25;8(1):373
Cell death discovery 2022 Aug 25;8(1):373
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Liu M, Yue Z, Zhang B, Li F, Liu L, Li F
Metabolites 2022 Aug 25;12(9)
Metabolites 2022 Aug 25;12(9)
Autophagy: A New Mechanism for Esketamine as a Depression Therapeutic.
Jiang G, Wang Y, Liu Q, Gu T, Liu S, Yin A, Zhang L
Neuroscience 2022 Aug 21;498:214-223
Neuroscience 2022 Aug 21;498:214-223
Arsenic Prodrug-Mediated Tumor Microenvironment Modulation Platform for Synergetic Glioblastoma Therapy.
Yan J, Hanif S, Zhang D, Ismail M, Wang X, Li Q, Shi B, Muhammad P, Wu H
ACS applied materials & interfaces 2022 Aug 17;14(32):36487-36502
ACS applied materials & interfaces 2022 Aug 17;14(32):36487-36502
Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy.
Gu L, Zhang J, Liu D, Chen J, Liu S, Peng Q, Tian Y, Du M, Zhang J, Xiao W, Shen S, Wang J
Journal of nanobiotechnology 2022 Aug 13;20(1):376
Journal of nanobiotechnology 2022 Aug 13;20(1):376
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10.
Liu Y, Zhang X, Wang J, Yang F, Luo W, Huang J, Chen M, Wang S, Li C, Zhang W, Chao J
Respiratory research 2022 Aug 12;23(1):204
Respiratory research 2022 Aug 12;23(1):204
Autophagic degradation of claudin-5 mediated by its binding to a Clostridium perfringens enterotoxin fragment modulates endothelial barrier permeability.
Lin P, Tan R, Yu P, Li Y, Mo Y, Li W, Zhang J
FEBS letters 2022 Apr;596(7):924-937
FEBS letters 2022 Apr;596(7):924-937
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
He W, Zhou X, Wu Q, Zhou L, Zhang Z, Zhang R, Deng C, Zhang X
Journal of molecular histology 2022 Apr;53(2):511-521
Journal of molecular histology 2022 Apr;53(2):511-521
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Yu K, Tan Z, Xin Y
Molecular biology reports 2022 Apr;49(4):2785-2793
Molecular biology reports 2022 Apr;49(4):2785-2793
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Zeng L, He J, Liu C, Zhang F, Zhang Z, Chen H, Wang Q, Ding X, Luo H
Inflammation 2022 Apr;45(2):725-738
Inflammation 2022 Apr;45(2):725-738
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Yuan T, Wang J, Shi C, Wang Y, Xia B, Xu W, Yang H, Yang Y, Ye MT, Khalid S, Liang Y, Tian C, You MJ, Wang Y
Hematological oncology 2022 Apr;40(2):249-257
Hematological oncology 2022 Apr;40(2):249-257
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Wu XY, Wang T, Hu HX, Zhang K, Zhao Y, Zhao BB, Lou HX, Wang XN, Shen T
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
Apelin-13/APJ induces cardiomyocyte hypertrophy by activating the Pannexin-1/P2X7 axis and FAM134B-dependent reticulophagy.
Yang Y, Zhang K, Huang S, Chen W, Mao H, Ouyang X, Chen L, Li L
Journal of cellular physiology 2022 Apr;237(4):2230-2248
Journal of cellular physiology 2022 Apr;237(4):2230-2248
All-In-One Biomimetic Nanoplatform Based on Hollow Polydopamine Nanoparticles for Synergistically Enhanced Radiotherapy of Colon Cancer.
Gong L, Zhang Y, Zhao J, Zhang Y, Tu K, Jiao L, Xu Q, Zhang M, Han S
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(14):e2107656
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(14):e2107656
MOXD1 knockdown suppresses the proliferation and tumor growth of glioblastoma cells via ER stress-inducing apoptosis.
Shi P, Xu J, Xia F, Wang Y, Ren J, Liang P, Cui H
Cell death discovery 2022 Apr 7;8(1):174
Cell death discovery 2022 Apr 7;8(1):174
Interpreting the Pharmacological Mechanisms of Sho-saiko-to on Thyroid Carcinoma through Combining Network Pharmacology and Experimental Evaluation.
Wang K, Qian R, Li H, Wang C, Ding Y, Gao Z
ACS omega 2022 Apr 5;7(13):11166-11176
ACS omega 2022 Apr 5;7(13):11166-11176
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
Usman M, Li Y, Ke Y, Chhetri G, Islam MA, Wang Z, Li X
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
HMGB1-mediated autophagy promotes gefitinib resistance in human non-small cell lung cancer.
Lei T, Huang J, Xie F, Gu J, Cheng Z, Wang Z
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):514-523
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):514-523
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Cheng F, Dun Y, Cheng J, Ripley-Gonzalez JW, Jiang W, You B, Liu S
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420
Food & function 2022 Apr 20;13(8):4399-4420
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
You B, Zhang P, Gu M, Yin H, Fan Y, Yao H, Pan S, Xie H, Cheng T, Liu H, You Y, Liu J
Cancer letters 2022 Apr 10;531:14-26
Cancer letters 2022 Apr 10;531:14-26
Ethanol potentiates mirtazapine-induced cardiotoxicity by inducing dysfunctional autophagy via HMGB1-dependent Akt/mTOR signaling pathway.
Zhu R, Liu X, Xue Q, Dong X, Zhang T, Jiang Y
Toxicology letters 2022 Apr 1;358:27-39
Toxicology letters 2022 Apr 1;358:27-39
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Wu M, Cong Y, Wang K, Yu H, Zhang X, Ma M, Duan Z, Pei X
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Ecotoxicology and environmental safety 2022 Apr 1;234:113395
Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction.
Luo C, Zhou X, Wang L, Zeng Q, Fan J, He S, Zhang H, Wei A
PeerJ 2021;9:e11986
PeerJ 2021;9:e11986
CHNQD-00603 Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by the miR-452-3p-Mediated Autophagy Pathway.
Xin S, Li SM, Gao L, Zheng JJ, Wu YW, Shao CL, Ren WH, Zhi K
Frontiers in cell and developmental biology 2021;9:779287
Frontiers in cell and developmental biology 2021;9:779287
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
Luo Q, Li X, Gan G, Yang M, Chen X, Chen F
Frontiers in cell and developmental biology 2021;9:764263
Frontiers in cell and developmental biology 2021;9:764263
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Gui Z, Zhao Z, Sun Q, Shao G, Huang J, Zhao W, Kuang Y
Frontiers in cell and developmental biology 2021;9:749129
Frontiers in cell and developmental biology 2021;9:749129
Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole-Based RalA Inhibitors Against Hepatocellular Carcinoma.
Wang Y, He M, Li X, Chai J, Jiang Q, Peng C, He G, Huang W
Frontiers in chemistry 2021;9:700956
Frontiers in chemistry 2021;9:700956
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Zhang M, Bai Y, Xu C, Qi Y, Meng J, Zhang W, Su H, Yan W
Frontiers in cell and developmental biology 2021;9:650846
Frontiers in cell and developmental biology 2021;9:650846
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Li C, Zhu Y, Wu Y, Fu M, Wu Y, Wu Y, Qiu Y, Zhang H, Ding M
Frontiers in medicine 2021;8:813047
Frontiers in medicine 2021;8:813047
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties.
Zhang J, Zhao T, Wang C, Meng Q, Huo X, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
Oxidative medicine and cellular longevity 2021;2021:7467156
Oxidative medicine and cellular longevity 2021;2021:7467156
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Zhang J, Cheng P, Dai W, Ji J, Wu L, Feng J, Wu J, Yu Q, Li J, Guo C
PPAR research 2021;2021:6658944
PPAR research 2021;2021:6658944
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways.
Ji J, Yu Q, Dai W, Wu L, Feng J, Zheng Y, Li Y, Guo C
PPAR research 2021;2021:6651839
PPAR research 2021;2021:6651839
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway.
Wu L, Yu Q, Cheng P, Guo C
PPAR research 2021;2021:6626295
PPAR research 2021;2021:6626295
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Zhao J, Lan W, Peng J, Guan B, Liu J, Zhang M, Zhan Z, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5631942
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Li L, Li H, Li Y, Feng J, Guan D, Zhang Y, Fu Y, Li S, Li C
Oxidative medicine and cellular longevity 2021;2021:5594059
Oxidative medicine and cellular longevity 2021;2021:5594059
Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration.
Song S, Bao S, Zhang C, Zhang J, Lv J, Li X, Chudhary M, Ren X, Kong L
Oxidative medicine and cellular longevity 2021;2021:5587340
Oxidative medicine and cellular longevity 2021;2021:5587340
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway.
He J, Liu J, Huang Y, Tang X, Xiao H, Liu Z, Jiang Z, Zeng L, Hu Z, Lu M
Oxidative medicine and cellular longevity 2021;2021:4805040
Oxidative medicine and cellular longevity 2021;2021:4805040
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells.
Luo R, Li S, Li G, Lu S, Zhang W, Liu H, Lei J, Ma L, Ke W, Liao Z, Wang B, Song Y, Wang K, Zhang Y, Yang C
Oxidative medicine and cellular longevity 2021;2021:3843145
Oxidative medicine and cellular longevity 2021;2021:3843145
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice.
Jiang L, Shen X, Dun Y, Xie M, Fu S, Zhang W, Qiu L, Ripley-Gonzalez JW, Liu S
International journal of medical sciences 2021;18(7):1680-1686
International journal of medical sciences 2021;18(7):1680-1686
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
Li L, Yu S, Hu Q, Hai Y, Li Y
International journal of biological sciences 2021;17(12):3133-3144
International journal of biological sciences 2021;17(12):3133-3144
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
Effect of Vitamin D Deficiency and Supplementation in Lactation and Early Life on Allergic Airway Inflammation and the Expression of Autophagy-Related Genes in an Ovalbumin Mouse Model.
Zhou Y, Xue Y, Bao A, Han L, Bao W, Xia C, Tian X, Zhang M
Journal of inflammation research 2021;14:4125-4141
Journal of inflammation research 2021;14:4125-4141
Effect of GLUT1 Inhibition and Autophagy Modulation on the Growth and Migration of Laryngeal Carcinoma Stem Cells Under Hypoxic and Low-Glucose Conditions.
Chen XH, Liu J, Zhong JT, Zhou SH, Fan J
OncoTargets and therapy 2021;14:3069-3081
OncoTargets and therapy 2021;14:3069-3081
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Knockdown of VDAC1 alleviates the cognitive dysfunction secondary to sepsis-associated encephalopathy.
Cai M, Du B, Si Y, Miao J, Ge J, Zhang J, Song J, Bao H
American journal of translational research 2021;13(7):7538-7555
American journal of translational research 2021;13(7):7538-7555
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy.
Xu M, Hang H, Huang M, Li J, Xu D, Jiao J, Wang F, Wu H, Sun X, Gu J, Kong X, Gao Y
Cellular and molecular gastroenterology and hepatology 2021;12(2):567-584
Cellular and molecular gastroenterology and hepatology 2021;12(2):567-584
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Li T, Tang Z, Li C, Liu X, Cheng L, Yang Z, Zhu X, Liu W, Huang Y
Frontiers in pharmacology 2021;12:804615
Frontiers in pharmacology 2021;12:804615
Delivery of siRNA Using Functionalized Gold Nanorods Enhances Anti-Osteosarcoma Efficacy.
Zhang M, Lin J, Jin J, Yu W, Qi Y, Tao H
Frontiers in pharmacology 2021;12:799588
Frontiers in pharmacology 2021;12:799588
Curcumin is a Potential Adjuvant to Alleviates Diabetic Retinal Injury via Reducing Oxidative Stress and Maintaining Nrf2 Pathway Homeostasis.
Xie T, Chen X, Chen W, Huang S, Peng X, Tian L, Wu X, Huang Y
Frontiers in pharmacology 2021;12:796565
Frontiers in pharmacology 2021;12:796565
Sorafenib-Induced Autophagy Promotes Glycolysis by Upregulating the p62/HDAC6/HSP90 Axis in Hepatocellular Carcinoma Cells.
Yan X, Tian R, Sun J, Zhao Y, Liu B, Su J, Li M, Sun W, Xu X
Frontiers in pharmacology 2021;12:788667
Frontiers in pharmacology 2021;12:788667
The Disulfiram/Copper Complex Induces Autophagic Cell Death in Colorectal Cancer by Targeting ULK1.
Hu Y, Qian Y, Wei J, Jin T, Kong X, Cao H, Ding K
Frontiers in pharmacology 2021;12:752825
Frontiers in pharmacology 2021;12:752825
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Xiong M, Hu W, Tan Y, Yu H, Zhang Q, Zhao C, Yi Y, Wang Y, Wu Y, Wu M
Frontiers in physiology 2021;12:748040
Frontiers in physiology 2021;12:748040
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Yu HX, Lin W, Yang K, Wei LJ, Chen JL, Liu XY, Zhong K, Chen X, Pei M, Yang HT
Frontiers in pharmacology 2021;12:741801
Frontiers in pharmacology 2021;12:741801
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Chen L, Niu X, Qiao X, Liu S, Ma H, Shi X, He X, Zhong M
Frontiers in immunology 2021;12:739039
Frontiers in immunology 2021;12:739039
Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia.
Yu P, Li Y, Zhong G, Li W, Chen B, Zhang J
Frontiers in physiology 2021;12:737474
Frontiers in physiology 2021;12:737474
Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.
Yang W, Su J, Li M, Li T, Wang X, Zhao M, Hu X
Frontiers in pharmacology 2021;12:709526
Frontiers in pharmacology 2021;12:709526
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Xu ZQ, Zhang JJ, Kong N, Zhang GY, Ke P, Han T, Su DF, Liu C
Frontiers in pharmacology 2021;12:676589
Frontiers in pharmacology 2021;12:676589
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/β-Catenin/ABCG2 Axis.
Liao M, Wang C, Yang B, Huang D, Zheng Y, Wang S, Wang X, Zhang J, Tang C, Xu Z, He Y, Huang R, Zhang F, Wang Z, Wang N
Frontiers in pharmacology 2021;12:659297
Frontiers in pharmacology 2021;12:659297
Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wei W, Lu M, Lan XB, Liu N, Su WK, Dushkin AV, Yu JQ
Frontiers in pharmacology 2021;12:642415
Frontiers in pharmacology 2021;12:642415
Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats.
Zhang KK, Wang H, Qu D, Chen LJ, Wang LB, Li JH, Liu JL, Xu LL, Yoshida JS, Xu JT, Xie XL, Li DR
Frontiers in pharmacology 2021;12:641917
Frontiers in pharmacology 2021;12:641917
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats.
Su J, Gao C, Xie L, Fan Y, Shen Y, Huang Q, Wang N, Xu Y, Yang N, Gui D
Frontiers in pharmacology 2021;12:638422
Frontiers in pharmacology 2021;12:638422
Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart.
Li X, Meng C, Han F, Yang J, Wang J, Zhu Y, Cui X, Zuo M, Xu J, Chang B
Frontiers in pharmacology 2021;12:634365
Frontiers in pharmacology 2021;12:634365
Shengma Biejia Decoction Inhibits Cell Growth in Multiple Myeloma by Inducing Autophagy-Mediated Apoptosis Through the ERK/mTOR Pathway.
Dai H, Ma B, Dai X, Pang J, Wang J, Zhao Y, Wang M, Zhang H, Gao H, Qian S, Tian F, Sun X
Frontiers in pharmacology 2021;12:585286
Frontiers in pharmacology 2021;12:585286
Compensatory combination of mTOR and TrxR inhibitors to cause oxidative stress and regression of tumors.
Xia Y, Chen J, Yu Y, Wu F, Shen X, Qiu C, Zhang T, Hong L, Zheng P, Shao R, Xu C, Wu F, Chen W, Xie C, Cui R, Zou P
Theranostics 2021;11(9):4335-4350
Theranostics 2021;11(9):4335-4350
Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells.
Liu X, Wang S, Zheng H, Liu Q, Shen T, Wang X, Ren D
American journal of cancer research 2021;11(7):3496-3514
American journal of cancer research 2021;11(7):3496-3514
Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Zhang C
Theranostics 2021;11(10):4637-4654
Theranostics 2021;11(10):4637-4654
Decreased neuronal synaptosome associated protein 29 contributes to poststroke cognitive impairment by disrupting presynaptic maintenance.
Yan W, Fan J, Zhang X, Song H, Wan R, Wang W, Yin Y
Theranostics 2021;11(10):4616-4636
Theranostics 2021;11(10):4616-4636
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Wen D, Liu WL, Lu ZW, Cao YM, Ji QH, Wei WJ
Frontiers in oncology 2021;11:647034
Frontiers in oncology 2021;11:647034
Circular RNA TRAPPC6B inhibits intracellular Mycobacterium tuberculosis growth while inducing autophagy in macrophages by targeting microRNA-874-3p.
Luo HL, Pi J, Zhang JA, Yang EZ, Xu H, Luo H, Shen L, Peng Y, Liu GB, Song CM, Li KY, Wu XJ, Zheng BY, Shen HB, Chen ZW, Xu JF
Clinical & translational immunology 2021;10(2):e1254
Clinical & translational immunology 2021;10(2):e1254
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Yang B, Peng F, Zhang Y, Wang X, Wang S, Zheng Y, Zhang J, Zeng Y, Wang N, Peng C, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Mitochondrial dysfunction and mitophagy pathway activation in hepatitis E virus-infected livers of Mongolian gerbils.
Yang Y, Tian J, Zhang H, Ma M, Li H, Liu T, Yang Y, Liu T, She R
Virus research 2021 Sep;302:198369
Virus research 2021 Sep;302:198369
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
Ren X, Lv J, Fu Y, Zhang N, Zhang C, Dong Z, Chudhary M, Zhong S, Kong L, Kong H
Diabetes research and clinical practice 2021 Sep;179:109025
Diabetes research and clinical practice 2021 Sep;179:109025
The enhancement of Tetrandrine to gemcitabine-resistant PANC-1 cytochemical sensitivity involves the promotion of PI3K/Akt/mTOR-mediated apoptosis and AMPK-regulated autophagy.
Song J, Xu J, Guo J, Shang Y, Wang J, Wang T
Acta histochemica 2021 Sep;123(6):151769
Acta histochemica 2021 Sep;123(6):151769
Biofunctional magnesium-coated Ti6Al4V scaffolds promote autophagy-dependent apoptosis in osteosarcoma by activating the AMPK/mTOR/ULK1 signaling pathway.
Wei X, Tang Z, Wu H, Zuo X, Dong H, Tan L, Wang W, Liu Y, Wu Z, Shi L, Wang N, Li X, Xiao X, Guo Z
Materials today. Bio 2021 Sep;12:100147
Materials today. Bio 2021 Sep;12:100147
Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA.
Wang C, Qu L, Li S, Yin F, Ji L, Peng W, Luo H, Lu D, Liu X, Chen X, Kong L, Wang X
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
Journal of medicinal chemistry 2021 Sep 9;64(17):12630-12650
A Marine λ-Oligocarrageenan Inhibits Migratory and Invasive Ability of MDA-MB-231 Human Breast Cancer Cells through Actions on Heparanase Metabolism and MMP-14/MMP-2 Axis.
Cousin R, Groult H, Manseur C, Ferru-Clément R, Gani M, Havret R, Toucheteau C, Prunier G, Colin B, Morel F, Piot JM, Lanneluc I, Baranger K, Maugard T, Fruitier-Arnaudin I
Marine drugs 2021 Sep 28;19(10)
Marine drugs 2021 Sep 28;19(10)
Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control.
Zhang W, You B, Qi D, Qiu L, Ripley-Gonzalez JW, Zheng F, Fu S, Li C, Dun Y, Liu S
Scientific reports 2021 Sep 27;11(1):19116
Scientific reports 2021 Sep 27;11(1):19116
The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
Núñez-Vázquez S, Saura-Esteller J, Sánchez-Vera I, Guilbaud E, Cosialls AM, Pons G, Ricci JE, Iglesias-Serret D, Marchetti S, Gil J
Oncogenesis 2021 Sep 27;10(9):64
Oncogenesis 2021 Sep 27;10(9):64
Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway.
Lu H, Jia C, Wu D, Jin H, Lin Z, Pan J, Li X, Wang W
Cell death & disease 2021 Sep 23;12(10):865
Cell death & disease 2021 Sep 23;12(10):865
Inhibition of endoplasmic reticulum stress-related autophagy attenuates MCLR-induced apoptosis in zebrafish testis and mouse TM4 cells.
Wu Z, Wang F, Hu L, Zhang J, Chen D, Zhao S
Ecotoxicology and environmental safety 2021 Sep 15;221:112438
Ecotoxicology and environmental safety 2021 Sep 15;221:112438
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q
Aging 2021 Sep 14;13(17):21202-21215
Aging 2021 Sep 14;13(17):21202-21215
Sitagliptin attenuates endothelial dysfunction independent of its blood glucose controlling effect.
Chang XM, Xiao F, Pan Q, Wang XX, Guo LX
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Sep 1;25(5):425-437
Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy.
Niu L, Chen S, Yang X, Ma C, Pan C, Wang H, Li Q, Geng F, Tang X
Oral diseases 2021 Oct;27(7):1775-1788
Oral diseases 2021 Oct;27(7):1775-1788
Hsa_circ_0004058 inhibits apoptosis of SRA01/04 cells by promoting autophagy via miR-186/ATG7 axis.
Wang Y, Wu Z, Huang Y, Zhang Y
Experimental eye research 2021 Oct;211:108721
Experimental eye research 2021 Oct;211:108721
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Qian J, Wang X, Weng W, Zhou G, Zhu S, Liu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112062
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:112062
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218.
Hu P, Li H, Sun W, Wang H, Yu X, Qing Y, Wang Z, Zhu M, Xu J, Guo Q, Hui H
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3178-3192
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3178-3192
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Zhao Y, Yang X, Li S, Zhang B, Li S, Wang X, Wang Y, Jia C, Chang Y, Wei W
Stem cell research & therapy 2021 Oct 9;12(1):535
Stem cell research & therapy 2021 Oct 9;12(1):535
The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.
Chen C, Ding W, Li J, Geng X, Zhang H, Sun Y
Journal of ethnopharmacology 2021 Oct 8;:114730
Journal of ethnopharmacology 2021 Oct 8;:114730
ERRFI1 induces apoptosis of hepatocellular carcinoma cells in response to tryptophan deficiency.
Cui M, Liu D, Xiong W, Wang Y, Mi J
Cell death discovery 2021 Oct 4;7(1):274
Cell death discovery 2021 Oct 4;7(1):274
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Han J, Wang L, Lv H, Liu J, Dong Y, Shi L, Ji Q
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Archives of biochemistry and biophysics 2021 Oct 30;711:109024
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B
Acta neuropathologica communications 2021 Oct 18;9(1):169
Acta neuropathologica communications 2021 Oct 18;9(1):169
Co-modification with MSC membrane and PDA prevents Fe(3)O(4)-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Yao H, Yan J, Shao P, Wang Y, Liu T, Jiang J, Liu T
Toxicology letters 2021 Oct 15;351:145-154
Toxicology letters 2021 Oct 15;351:145-154
Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway.
Chu Y, Zhu C, Yue C, Peng W, Chen W, He G, Liu C, Lv Y, Gao G, Yao K, Han R, Hu X, Zhang Y, Ye Y
Cell & bioscience 2021 Oct 13;11(1):182
Cell & bioscience 2021 Oct 13;11(1):182
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells.
Xu J, Wang Y, Wang Y, Wang Z, He X
Chemico-biological interactions 2021 Oct 1;348:109648
Chemico-biological interactions 2021 Oct 1;348:109648
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy.
Zhu X, Cao Y, Su M, Chen M, Li C, Yi L, Qin J, Tulake W, Teng F, Zhong Y, Tang W, Wang S, Dong J
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Yang X, Jin N, Wang Y, Yao Y, Wang Y, Li T, Liu C, Yu T, Yin H, Zhang Z, Cheng SY, Yue S
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606
Autophagy 2021 Nov;17(11):3592-3606
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Fan Y, Lu J, Liu J, Zhang R, Yu Z, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Liquiritigenin protects against arsenic trioxide-induced liver injury by inhibiting oxidative stress and enhancing mTOR-mediated autophagy.
Zhang M, Xue Y, Zheng B, Li L, Chu X, Zhao Y, Wu Y, Zhang J, Han X, Wu Z, Chu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112167
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112167
Autophagy is required for the promoting effect of angiogenic factor with G patch domain and forkhead-associated domain 1 (AGGF1) in retinal angiogenesis.
Li R, Yao G, Zhou L, Zhang M, Yan J, Wang X, Li Y
Microvascular research 2021 Nov;138:104230
Microvascular research 2021 Nov;138:104230
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
Zhao Y, Li WF, Li QJ, He SW, He QM, Long LF, Liu N, Ma J
Oral oncology 2021 Nov;122:105576
Oral oncology 2021 Nov;122:105576
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
Guo X, Bao X, Wang X, Liu D, Liu P, Chi T, Ji X, Zheng Z, Chen G, Zou L
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
Downregulation of miR-29c promotes muscle wasting by modulating the activity of leukemia inhibitory factor in lung cancer cachexia.
Xie K, Xiong H, Xiao W, Xiong Z, Hu W, Ye J, Xu N, Shi J, Yuan C, Chen Z, Miao D, Zhang X, Yang H
Cancer cell international 2021 Nov 27;21(1):627
Cancer cell international 2021 Nov 27;21(1):627
Long non-coding RNA LINC01559 exerts oncogenic role via enhancing autophagy in lung adenocarcinoma.
Zhao Z, Wan J, Guo M, Yang Z, Li Z, Wang Y, Ming L
Cancer cell international 2021 Nov 25;21(1):624
Cancer cell international 2021 Nov 25;21(1):624
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Li M, Cheng W, Zhang L
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Metallomics : integrated biometal science 2021 Nov 19;13(11)
Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy.
Wang W, Wang L, Yang M, Wu C, Lan R, Wang W, Li Y
Cell death & disease 2021 Nov 10;12(11):1069
Cell death & disease 2021 Nov 10;12(11):1069
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
Meng Z, Liu X, Li T, Fang T, Cheng Y, Han L, Sun B, Chen L
International immunopharmacology 2021 May;94:107492
International immunopharmacology 2021 May;94:107492
Hepatic COX-2 expression protects mice from an alcohol-high fat diet-induced metabolic disorder by involving protein acetylation related energy metabolism.
Chen M, Sun X, Wei W, Cucarella C, Martín-Sanz P, Casado M, Pi L, Ren B, Cao Q
Alcohol (Fayetteville, N.Y.) 2021 May;92:41-52
Alcohol (Fayetteville, N.Y.) 2021 May;92:41-52
Comparison of toxicity of Ti(3) C(2) and Nb(2) C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Gu M, Dai Z, Yan X, Ma J, Niu Y, Lan W, Wang X, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Journal of applied toxicology : JAT 2021 May;41(5):745-754
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
Hu J, Huo S, Dou S, Jiang W, Li Y
General physiology and biophysics 2021 May;40(3):161-171
General physiology and biophysics 2021 May;40(3):161-171
Roles of endoplasmic reticulum stress in 2,2',4,4'-tetrabromodiphenylether-induced thyroid cell apoptosis and autophagy.
Ma R, Li B, Zhang C, Lei R, Zhang X, Wang C, Zhang S, Wang A
Ecotoxicology and environmental safety 2021 May;214:112077
Ecotoxicology and environmental safety 2021 May;214:112077
17β-estradiol improves the developmental ability, inhibits reactive oxygen species levels and apoptosis of porcine oocytes by regulating autophagy events.
Duan J, Chen H, Xu D, Li Y, Li X, Cheng J, Hua R, Zhang Z, Yang L, Li Q
The Journal of steroid biochemistry and molecular biology 2021 May;209:105826
The Journal of steroid biochemistry and molecular biology 2021 May;209:105826
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, Fan H, Meng T, He Z, Huang H, Gong Q, Zhu D, Xu Y, He P, Li L, Feng D
Autophagy 2021 May;17(5):1142-1156
Autophagy 2021 May;17(5):1142-1156
miR-338-3p inhibits autophagy in a rat model of allergic rhinitis after PM2.5 exposure through AKT/mTOR signaling by targeting UBE2Q1.
Wang JC, Huang Y, Zhang RX, Han ZJ, Zhou LL, Sun N, Dong WY, Zhuang GS
Biochemical and biophysical research communications 2021 May 21;554:1-6
Biochemical and biophysical research communications 2021 May 21;554:1-6
The nicotinamide phosphoribosyltransferase antagonist FK866 inhibits growth of prostate tumour spheroids and increases doxorubicin retention without changes in drug transporter and cancer stem cell protein expression.
Sauer H, Kampmann H, Khosravi F, Sharifpanah F, Wartenberg M
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):422-434
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):422-434
Uhrf1 regulates H3K9me2 modification of mTOR to inhibit the effect of autophagy in myocardial ischemia-reperfusion injury.
Li HG, Tian WH, Qin CL, Ye RR, Liu DH, Liu HW
Aging 2021 Mar 19;13(7):9704-9718
Aging 2021 Mar 19;13(7):9704-9718
Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src.
Liu H, Zhou Y, Qiu H, Zhuang R, Han Y, Liu X, Qiu X, Wang Z, Xu L, Tan R, Hong W, Wang T
Cell death & disease 2021 Mar 17;12(4):284
Cell death & disease 2021 Mar 17;12(4):284
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation.
Li C, Shi L, Peng C, Yu G, Zhang Y, Du Z
Chemico-biological interactions 2021 Mar 1;337:109331
Chemico-biological interactions 2021 Mar 1;337:109331
PFKP facilitates ATG4B phosphorylation during amino acid deprivation-induced autophagy.
Li X, Sun L, Yan G, Yan X
Cellular signalling 2021 Jun;82:109956
Cellular signalling 2021 Jun;82:109956
Oroxylin A is a severe acute respiratory syndrome coronavirus 2-spiked pseudotyped virus blocker obtained from Radix Scutellariae using angiotensin-converting enzyme II/cell membrane chromatography.
Gao J, Ding Y, Wang Y, Liang P, Zhang L, Liu R
Phytotherapy research : PTR 2021 Jun;35(6):3194-3204
Phytotherapy research : PTR 2021 Jun;35(6):3194-3204
Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy.
Zhu Y, Su Y, Zhang J, Zhang Y, Li Y, Han Y, Dong X, Li W, Li W
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells.
Xu J, Wang Y, Wang Z, Wang Y, He X
Steroids 2021 Jun;170:108828
Steroids 2021 Jun;170:108828
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)
The Journal of cell biology 2021 Jun 7;220(6)
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models.
Niu M, Li L, Su Z, Wei L, Pu W, Zhao C, Ding Y, Wazir J, Cao W, Song S, Gao Q, Wang H
Cell death & disease 2021 Jun 26;12(7):652
Cell death & disease 2021 Jun 26;12(7):652
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats.
Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Ecotoxicology and environmental safety 2021 Jun 15;216:112181
Study on the anti-hepatocarcinoma effect and molecular mechanism of Prunella vulgaris total flavonoids.
Song YG, Kang L, Tian S, Cui LL, Li Y, Bai M, Fang XY, Cao LH, Coleman K, Miao MS
Journal of ethnopharmacology 2021 Jun 12;273:113891
Journal of ethnopharmacology 2021 Jun 12;273:113891
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.
Cao Q, Luo J, Xiong Y, Liu Z, Ye Q
International immunopharmacology 2021 Jul;96:107643
International immunopharmacology 2021 Jul;96:107643
Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition.
Zhu F, Li X, Tang X, Jiang J, Han Y, Li Y, Ma C, Liu Z, He Y
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
Aflatoxin B1 inhibited autophagy flux by inducing lysosomal alkalinization in HepG2 cells.
Zhang Q, Feng Z, Lu J, Lu J, Guan S, Chen Y
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
Toxicology mechanisms and methods 2021 Jul;31(6):450-456
TCDD induced lipid accumulation by impairment of autophagic flux in THP-1 macrophages.
Lu J, Liu M, Fan Y, Zheng H, Guan S
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
Environmental science and pollution research international 2021 Jul;28(27):36053-36059
The Difference in Expression of Autophagy-Related Proteins in Lesional and Perilesional Skin in Adult Patients with Active and Stable Generalized Vitiligo-A Cross-Sectional Pilot Study.
Yu H, Lin X, Huang Y, Cheng H, Seifert O
Indian journal of dermatology 2021 Jul-Aug;66(4):331-336
Indian journal of dermatology 2021 Jul-Aug;66(4):331-336
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Peng Y, Zhang Y, Zhang Y, Wang X, Xia Y
Chinese medicine 2021 Jul 28;16(1):66
Chinese medicine 2021 Jul 28;16(1):66
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Bai Z, Ding N, Ge J, Wang Y, Wang L, Wu N, Wei Q, Xu S, Liu X, Zhou G
Cell biology international 2021 Jan;45(1):177-187
Cell biology international 2021 Jan;45(1):177-187
Pharmacological activation of REV-ERBα improves nonalcoholic steatohepatitis by regulating intestinal permeability.
Ni Y, Zhao Y, Ma L, Wang Z, Ni L, Hu L, Fu Z
Metabolism: clinical and experimental 2021 Jan;114:154409
Metabolism: clinical and experimental 2021 Jan;114:154409
Resveratrol attenuates cigarette smoke induced endothelial apoptosis by activating Notch1 signaling mediated autophagy.
Zong DD, Liu XM, Li JH, Ouyang RY, Long YJ, Chen P, Chen Y
Respiratory research 2021 Jan 19;22(1):22
Respiratory research 2021 Jan 19;22(1):22
Atmospheric PM(2.5) blocking up autophagic flux in HUVECs via inhibiting Sntaxin-17 and LAMP2.
Liu Y, Zhao D, Peng W, Xue P, Jiang X, Chen S, Gao H, Wang X, Feng S
Ecotoxicology and environmental safety 2021 Jan 15;208:111450
Ecotoxicology and environmental safety 2021 Jan 15;208:111450
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation.
Hu P, Wang J, Qing Y, Li H, Sun W, Yu X, Hui H, Guo Q, Xu J
Cell death & disease 2021 Jan 13;12(1):80
Cell death & disease 2021 Jan 13;12(1):80
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
Liu Y, Wang Y, Liu J, Kang R, Tang D
Cancer gene therapy 2021 Feb;28(1-2):55-63
Cancer gene therapy 2021 Feb;28(1-2):55-63
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Yu Q, Cheng P, Wu J, Guo C
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Li J, Xie J, Wang YZ, Gan YR, Wei L, Ding GW, Ding YH, Xie DX
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
Cholecalciferol (vitamin D(3)) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes.
Teixeira MA, De Feudis M, Reano S, Raiteri T, Scircoli A, Zaggia I, Ruga S, Salvadori L, Prodam F, Marzullo P, Molinari C, Corà D, Filigheddu N
Aging 2021 Feb 22;13(4):4895-4910
Aging 2021 Feb 22;13(4):4895-4910
Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities.
Zhang X, Qin Y, Wan X, Liu H, Lv C, Ruan W, He L, Lu L, Guo X
Journal of translational medicine 2021 Feb 10;19(1):62
Journal of translational medicine 2021 Feb 10;19(1):62
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Lu J, Lu J, Bu X, Li Y, Ge G, Guan S
Journal of food science 2021 Dec;86(12):5503-5515
Journal of food science 2021 Dec;86(12):5503-5515
Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway.
Zheng J, Hu S, Wang J, Zhang X, Yuan D, Zhang C, Liu C, Wang T, Zhou Z
Pharmaceutical biology 2021 Dec;59(1):183-191
Pharmaceutical biology 2021 Dec;59(1):183-191
The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells.
Okubo K, REßING N, Schulz WA, Hansen FK, Asano T, Sato A
Anticancer research 2021 Dec;41(12):5987-5996
Anticancer research 2021 Dec;41(12):5987-5996
Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway.
Liu L, Cao Q, Gao W, Li BY, Zeng C, Xia Z, Zhao B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22040
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22040
Lanthanum chloride induces autophagy in primary cultured rat cortical neurons through Akt/mTOR and AMPK/mTOR signaling pathways.
Gao X, Yu M, Sun W, Han Y, Yang J, Lu X, Jin C, Wu S, Cai Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112632
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112632
N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy.
Long CM, Zheng QX, Zhou Y, Liu YT, Gong LP, Zeng YC, Liu S
Journal of pharmacological sciences 2021 Dec;147(4):315-324
Journal of pharmacological sciences 2021 Dec;147(4):315-324
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Chen X, Tang H, Liang Y, Wu P, Xie L, Ding Y, Yang P, Long B, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2).
Pei L, Lv X, Jia G, Tan X, Li M, Zhang A
Bioengineered 2021 Dec;12(1):8279-8295
Bioengineered 2021 Dec;12(1):8279-8295
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Hong Y, Zhou Y, Shen L, Wei Y, Long C, Fu Y, Wu H, Wang J, Wu Y, Wu S, Wei G
Ecotoxicology and environmental safety 2021 Dec 20;227:112889
Ecotoxicology and environmental safety 2021 Dec 20;227:112889
Alleviation of CCCP-induced mitochondrial injury by augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy.
Zhang J, Chen S, Li Y, Xiao W, An W
Experimental cell research 2021 Dec 1;409(1):112866
Experimental cell research 2021 Dec 1;409(1):112866
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy.
Guo Z, Yu B, Li X, Yang X, Wang C, Fan L
Journal of molecular histology 2021 Aug;52(4):799-808
Journal of molecular histology 2021 Aug;52(4):799-808
Atorvastatin reverses high cholesterol-induced cardiac remodelling and regulates mitochondrial quality-control in a cholesterol-independent manner: An experimental study.
Zheng P, Ding Y, Lu F, Liu N, Wu H, Bian Z, Chen X, Yang D
Clinical and experimental pharmacology & physiology 2021 Aug;48(8):1150-1161
Clinical and experimental pharmacology & physiology 2021 Aug;48(8):1150-1161
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Tao M, Zheng D, Liang X, Wu D, Hu K, Jin J, He Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis.
Wang Q, Liang D, Shen P, Yu Y, Yan Y, You W
Translational oncology 2021 Aug;14(8):101045
Translational oncology 2021 Aug;14(8):101045
CIDEC silencing attenuates diabetic nephropathy via inhibiting apoptosis and promoting autophagy.
Zheng GS, Tan YM, Shang YY, Liu YP, Hu BA, Wang D, Han L, Wang ZH, Zhang W, Ti Y, Zhong M
Journal of diabetes investigation 2021 Aug;12(8):1336-1345
Journal of diabetes investigation 2021 Aug;12(8):1336-1345
Autophagy-associated circular RNA hsa_circ_0007813 modulates human bladder cancer progression via hsa-miR-361-3p/IGF2R regulation.
Zhang Z, Mou Z, Xu C, Wu S, Dai X, Chen X, Ou Y, Chen Y, Yang C, Jiang H
Cell death & disease 2021 Aug 7;12(8):778
Cell death & disease 2021 Aug 7;12(8):778
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Advanced oxidation protein products impair autophagic flux in macrophage by inducing lysosomal dysfunction via activation of PI3K-Akt-mTOR pathway in Crohn's disease.
Liao Y, Xu J, Qin B, Shi J, Qin C, Xie F, Ou S, Tang J, Wang W, Wu F, Bai L
Free radical biology & medicine 2021 Aug 20;172:33-47
Free radical biology & medicine 2021 Aug 20;172:33-47
Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish.
Sun CC, Zhou ZQ, Chen ZL, Zhu RK, Yang D, Peng XY, Zheng L, Tang CF
Biology 2021 Aug 10;10(8)
Biology 2021 Aug 10;10(8)
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Wang J, Zhou F, Li F, Wang B, Hu Y, Li X
Annals of translational medicine 2021 Apr;9(7):568
Annals of translational medicine 2021 Apr;9(7):568
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Ji Q, Qiao X, Liu Y, Wang D
Histology and histopathology 2021 Apr;36(4):475-484
Histology and histopathology 2021 Apr;36(4):475-484
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Liu X, Gu Y, Bian Y, Cai D, Li Y, Zhao Y, Zhang Z, Xue M, Zhang L
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Apoptosis : an international journal on programmed cell death 2021 Apr;26(3-4):195-208
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.
Nie L, Liu M, Chen J, Wu Q, Li Y, Yi J, Zheng X, Zhang J, Chu C, Yang J
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.
Lu J, Fan Y, Liu M, Zhang Q, Guan S
Toxicology 2021 Apr 30;454:152716
Toxicology 2021 Apr 30;454:152716
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Tan YZ, Xu XY, Dai JM, Yin Y, He XT, Zhang YL, Zhu TX, An Y, Tian BM, Chen FM
Stem cell research & therapy 2021 Apr 29;12(1):254
Stem cell research & therapy 2021 Apr 29;12(1):254
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Liu A, Wang W, Lu Z, Liu Z, Zhou W, Zhong Z, Ye Q
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Xiao W, Yeerken D, Li J, Li Z, Jiang L, Li D, Fu M, Ma L, Song Y, Zhang W, Zhan Q
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Du J, Dong Z, Tan L, Tan M, Zhang F, Zhang K, Pan G, Li C, Shi S, Zhang Y, Liu Y, Cui H
Frontiers in cell and developmental biology 2020;8:607757
Frontiers in cell and developmental biology 2020;8:607757
Upregulation of Parkin Accelerates Osteoblastic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells and Bone Regeneration by Enhancing Autophagy and β-Catenin Signaling.
Zhang W, Hou W, Chen M, Chen E, Xue D, Ye C, Li W, Pan Z
Frontiers in cell and developmental biology 2020;8:576104
Frontiers in cell and developmental biology 2020;8:576104
Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis.
Wang MJ, Yang CH, Jin Y, Wan CB, Qian WH, Xing F, Li X, Liu YY
The American journal of Chinese medicine 2020;48(1):143-160
The American journal of Chinese medicine 2020;48(1):143-160
Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytes.
Huang Y, Liao Y, Zhang H, Li S
The Journal of toxicological sciences 2020;45(9):559-567
The Journal of toxicological sciences 2020;45(9):559-567
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway.
Feng J, Li C, Xu R, Li Y, Hou Q, Feng R, Wang S, Zhang L, Li C
Oxidative medicine and cellular longevity 2020;2020:9762390
Oxidative medicine and cellular longevity 2020;2020:9762390
Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling.
Huang Y, Wang Y, Meng S, Chen Z, Kong H, Pan T, Lu G, Li X
Mediators of inflammation 2020;2020:9527147
Mediators of inflammation 2020;2020:9527147
Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro.
Li D, Pei X, Qin X, Liu X, Li C, Li L, Dai C, Xiao X, Tang S
Oxidative medicine and cellular longevity 2020;2020:8835207
Oxidative medicine and cellular longevity 2020;2020:8835207
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Kuang M, Yang M, Li L, Li C, Wang G
Oxidative medicine and cellular longevity 2020;2020:4045674
Oxidative medicine and cellular longevity 2020;2020:4045674
Alantolactone inhibits cell autophagy and promotes apoptosis via AP2M1 in acute lymphoblastic leukemia.
Shi C, Lan W, Wang Z, Yang D, Wei J, Liu Z, Teng Y, Gu M, Yuan T, Cao F, Zhou J, Li Y
Cancer cell international 2020;20:442
Cancer cell international 2020;20:442
TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis.
Wang D, Qi H, Zhang H, Zhou W, Li Y, Li A, Liu Q, Wang Y
International journal of biological sciences 2020;16(7):1180-1193
International journal of biological sciences 2020;16(7):1180-1193
Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1(G93A) Mice.
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, Xu R
International journal of biological sciences 2020;16(2):284-297
International journal of biological sciences 2020;16(2):284-297
Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis.
You G, Long X, Song F, Huang J, Tian M, Xiao Y, Deng S, Wu Q
Drug design, development and therapy 2020;14:457-468
Drug design, development and therapy 2020;14:457-468
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis.
Li Z, Cheng J, Liu J
Drug design, development and therapy 2020;14:2645-2655
Drug design, development and therapy 2020;14:2645-2655
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.
Xiang S, Chen K, Xu L, Wang T, Guo C
Drug design, development and therapy 2020;14:129-143
Drug design, development and therapy 2020;14:129-143
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
Long Noncoding RNA TUG1 Promotes Autophagy-Associated Paclitaxel Resistance by Sponging miR-29b-3p in Ovarian Cancer Cells.
Gu L, Li Q, Liu H, Lu X, Zhu M
OncoTargets and therapy 2020;13:2007-2019
OncoTargets and therapy 2020;13:2007-2019
Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation.
Zhang T, Wang H, Lu M, Zhao K, Yin J, Liu Y, Sun Y
American journal of translational research 2020;12(9):5332-5342
American journal of translational research 2020;12(9):5332-5342
MicroRNA-1276 Promotes Colon Cancer Cell Proliferation by Negatively Regulating LACTB.
Wang C, Shi Z, Hong Z, Pan J, Chen Z, Qiu C, Zhuang H, Zheng X
Cancer management and research 2020;12:12185-12195
Cancer management and research 2020;12:12185-12195
Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway.
Sun X, Wang D, Zhang T, Lu X, Duan F, Ju L, Zhuang X, Jiang X
Frontiers in pharmacology 2020;11:84
Frontiers in pharmacology 2020;11:84
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Li T, Fang T, Xu L, Liu X, Li X, Xue M, Yu X, Sun B, Chen L
Frontiers in pharmacology 2020;11:622153
Frontiers in pharmacology 2020;11:622153
Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes.
Duan YN, Ge X, Jiang HW, Zhang HJ, Zhao Y, Li JL, Zhang W, Li JY
Frontiers in endocrinology 2020;11:592818
Frontiers in endocrinology 2020;11:592818
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Wang N, Muhetaer G, Zhang X, Yang B, Wang C, Zhang Y, Wang X, Zhang J, Wang S, Zheng Y, Zhang F, Wang Z
Frontiers in pharmacology 2020;11:591400
Frontiers in pharmacology 2020;11:591400
Morroniside Inhibits H(2)O(2)-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Gao X, Liu Y, Wang L, Sai N, Liu Y, Ni J
Frontiers in pharmacology 2020;11:533809
Frontiers in pharmacology 2020;11:533809
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
Sun W, Li J, Zhou L, Han J, Liu R, Zhang H, Ning T, Gao Z, Liu B, Chen X, Ba Y
Theranostics 2020;10(5):1981-1996
Theranostics 2020;10(5):1981-1996
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
Fan L, Wang J, Cao Q, Ding X, Li B
American journal of cancer research 2020;10(1):314-335
American journal of cancer research 2020;10(1):314-335
Long Noncoding RNA UCA1 Is Related to Autophagy and Apoptosis in Endometrial Stromal Cells.
Jiang L, Wan Y, Feng Z, Liu D, Ouyang L, Li Y, Liu K
Frontiers in oncology 2020;10:618472
Frontiers in oncology 2020;10:618472
LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma.
Zhou B, Yang C, Yan X, Shi Z, Xiao H, Wei X, Jiang N, Wu Z
Frontiers in oncology 2020;10:606790
Frontiers in oncology 2020;10:606790
Disulfiram Chelated With Copper Inhibits the Growth of Gastric Cancer Cells by Modulating Stress Response and Wnt/β-catenin Signaling.
Wang L, Chai X, Wan R, Zhang H, Zhou C, Xiang L, Paul ME, Li Y
Frontiers in oncology 2020;10:595718
Frontiers in oncology 2020;10:595718
LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes.
Yang X, Niu L, Pan Y, Feng X, Liu J, Guo Y, Pan C, Geng F, Tang X
Frontiers in cellular and infection microbiology 2020;10:561761
Frontiers in cellular and infection microbiology 2020;10:561761
Autophagy Is a Potential Therapeutic Target Against Duck Tembusu Virus Infection in vivo.
Hu Z, Pan Y, Cheng A, Zhang X, Wang M, Chen S, Zhu D, Liu M, Yang Q, Wu Y, Zhao X, Huang J, Zhang S, Mao S, Ou X, Yu Y, Zhang L, Liu Y, Tian B, Pan L, Rehman MU, Yin Z, Jia R
Frontiers in cellular and infection microbiology 2020;10:155
Frontiers in cellular and infection microbiology 2020;10:155
Effect of combination of curcumin and GLUT-1 AS-ODN on radiosensitivity of laryngeal carcinoma through regulating autophagy.
Dai LB, Yu Q, Zhou SH, Bao YY, Zhong JT, Shen LF, Lu ZJ, Fan J, Huang YP
Head & neck 2020 Sep;42(9):2287-2297
Head & neck 2020 Sep;42(9):2287-2297
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
A lysosome-targeted ruthenium(II) polypyridyl complex as photodynamic anticancer agent.
Chen J, Tao Q, Wu J, Wang M, Su Z, Qian Y, Yu T, Wang Y, Xue X, Liu HK
Journal of inorganic biochemistry 2020 Sep;210:111132
Journal of inorganic biochemistry 2020 Sep;210:111132
A steroidal saponin isolated from Allium chinense simultaneously induces apoptosis and autophagy by modulating the PI3K/Akt/mTOR signaling pathway in human gastric adenocarcinoma.
Xu J, Zhang M, Lin X, Wang Y, He X
Steroids 2020 Sep;161:108672
Steroids 2020 Sep;161:108672
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Zheng T, Chen K, Zhang X, Feng H, Shi Y, Liu L, Zhang J, Chen Y
Aging 2020 Sep 8;12(18):18649-18659
Aging 2020 Sep 8;12(18):18649-18659
Globular CTRP9 protects cardiomyocytes from palmitic acid-induced oxidative stress by enhancing autophagic flux.
Zuo A, Li J, Zhao X, Li T, Lei S, Chen J, Xu D, Song C, Li N, Ruan S, Lyu L, Guo Y
Chemico-biological interactions 2020 Sep 25;329:109094
Chemico-biological interactions 2020 Sep 25;329:109094
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy.
Chou HC, Chen CH, Chou LY, Cheng TL, Kang L, Chuang SC, Lin YS, Ho ML, Wang YH, Lin SY, Wang CZ
International journal of molecular sciences 2020 Sep 23;21(19)
International journal of molecular sciences 2020 Sep 23;21(19)
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)
Journal of bacteriology 2020 Sep 23;202(20)
The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.
Jin C, Miao X, Zhong Y, Han J, Liu Q, Zhu J, Xia X, Peng X
Food & function 2020 Sep 23;11(9):7456-7467
Food & function 2020 Sep 23;11(9):7456-7467
4-Acetylantroquinonol B Inhibits Osteoclastogenesis by Inhibiting the Autophagy Pathway in a Simulated Microgravity Model.
Wu CH, Ou CH, Yen IC, Lee SY
International journal of molecular sciences 2020 Sep 22;21(18)
International journal of molecular sciences 2020 Sep 22;21(18)
Cellular evidence of autophagy in Sertoli cells during spermatogenesis in goats.
Qu W, Tarique I, Deng B, Zhang Y, Haseeb A, Chen Q, Yang P
Theriogenology 2020 Sep 15;154:237-245
Theriogenology 2020 Sep 15;154:237-245
Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway.
He W, Wang P, Chen Q, Li C
Skeletal muscle 2020 Sep 15;10(1):25
Skeletal muscle 2020 Sep 15;10(1):25
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
Gunda V, Pathania AS, Chava S, Prathipati P, Chaturvedi NK, Coulter DW, Pandey MK, Durden DL, Challagundla KB
Cancers 2020 Sep 10;12(9)
Cancers 2020 Sep 10;12(9)
The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway.
Xu Z, Feng J, Li Y, Guan D, Chen H, Zhai X, Zhang L, Li C, Li C
Chemico-biological interactions 2020 Sep 1;328:109196
Chemico-biological interactions 2020 Sep 1;328:109196
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, Wu Y, Zhai X, Zuo D
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Han L, Ma Q, Yu J, Gong Z, Ma C, Xu Y, Deng G, Wu X
Innate immunity 2020 Oct;26(7):580-591
Innate immunity 2020 Oct;26(7):580-591
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
Resveratrol inhibits hypertrophic scars formation by activating autophagy via the miR-4654/Rheb axis.
Pang K, Li B, Tang Z, Yang W, Hao L, Shi Z, Zhang J, Cai L, Li R, Liu Y, Lv Q, Ding J, Han C
Molecular medicine reports 2020 Oct;22(4):3440-3452
Molecular medicine reports 2020 Oct;22(4):3440-3452
3-Chloro-1, 2-propanediol inhibits autophagic flux by impairment of lysosomal function in HepG2 cells.
Lu J, Lu J, Chen Y, Feng Z, Liu S, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111575
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y
Nanotoxicology 2020 Oct;14(8):1017-1038
Nanotoxicology 2020 Oct;14(8):1017-1038
DUSP5 (dual-specificity protein phosphatase 5) suppresses BCG-induced autophagy via ERK 1/2 signaling pathway.
Luo J, Xue D, Song F, Liu X, Li W, Wang Y
Molecular immunology 2020 Oct;126:101-109
Molecular immunology 2020 Oct;126:101-109
Anticancer Effects of Honokiol via Mitochondrial Dysfunction Are Strongly Enhanced by the Mitochondria-Targeting Carrier Berberine.
Shi X, Zhang T, Lou H, Song H, Li C, Fan P
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Journal of medicinal chemistry 2020 Oct 22;63(20):11786-11800
Apigenin induced autophagy and stimulated autophagic lipid degradation.
Lu J, Meng Z, Chen Y, Yu L, Gao B, Zheng Y, Guan S
Food & function 2020 Oct 21;11(10):9208-9215
Food & function 2020 Oct 21;11(10):9208-9215
Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level.
Song W, Gao K, Huang P, Tang Z, Nie F, Jia S, Guo R
Life sciences 2020 Oct 15;259:118397
Life sciences 2020 Oct 15;259:118397
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S
International journal of molecular medicine 2020 Nov;46(5):1827-1837
International journal of molecular medicine 2020 Nov;46(5):1827-1837
Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice.
Ma L, Ni Y, Wang Z, Tu W, Ni L, Zhuge F, Zheng A, Hu L, Zhao Y, Zheng L, Fu Z
Gut microbes 2020 Nov 9;12(1):1-19
Gut microbes 2020 Nov 9;12(1):1-19
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells.
Wang J, Liu X, Zheng H, Liu Q, Zhang H, Wang X, Shen T, Wang S, Ren D
Chemico-biological interactions 2020 Nov 1;331:109279
Chemico-biological interactions 2020 Nov 1;331:109279
Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C.
Reimann L, Schwäble AN, Fricke AL, Mühlhäuser WWD, Leber Y, Lohanadan K, Puchinger MG, Schäuble S, Faessler E, Wiese H, Reichenbach C, Knapp B, Peikert CD, Drepper F, Hahn U, Kreutz C, van der Ven PFM, Radziwill G, Djinović-Carugo K, Fürst DO, Warscheid B
Communications biology 2020 May 22;3(1):253
Communications biology 2020 May 22;3(1):253
Inhibiting PKCβ2 protects HK-2 cells against meglumine diatrizoate and AGEs-induced apoptosis and autophagy.
Jiang W, Zhao W, Ye F, Huang S, Wu Y, Chen H, Zhou R, Fu G
Annals of translational medicine 2020 Mar;8(6):293
Annals of translational medicine 2020 Mar;8(6):293
Autophagy in endothelial cells regulates their haematopoiesis-supporting ability.
Lyu ZS, Cao XN, Wen Q, Mo XD, Zhao HY, Chen YH, Wang Y, Chang YJ, Xu LP, Zhang XH, Kong Y, Huang XJ
EBioMedicine 2020 Mar;53:102677
EBioMedicine 2020 Mar;53:102677
Autophagy and Hsp70 activation alleviate oral epithelial cell death induced by food-derived hypertonicity.
Yang J, Zhang H, Sun S, Wang X, Guan Y, Mi Q, Zeng W, Xiang H, Zhu H, Zou X, You Y, Xiang Y, Gao Q
Cell stress & chaperones 2020 Mar;25(2):253-264
Cell stress & chaperones 2020 Mar;25(2):253-264
Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition.
Baldini F, Portincasa P, Grasselli E, Damonte G, Salis A, Bonomo M, Florio M, Serale N, Voci A, Gena P, Vergani L, Calamita G
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Mar;1865(3):158586
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Mar;1865(3):158586
Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells.
Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, Xu Z, Wang X, Wang Y, Zhu Y, Wang W
Archives of oral biology 2020 Mar;111:104646
Archives of oral biology 2020 Mar;111:104646
NeuroHeal Treatment Alleviates Neuropathic Pain and Enhances Sensory Axon Regeneration.
Romeo-Guitart D, Casas C
Cells 2020 Mar 27;9(4)
Cells 2020 Mar 27;9(4)
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells.
Yu M, Zeng M, Pan Z, Wu F, Guo L, He G
European journal of medicinal chemistry 2020 Mar 1;189:112076
European journal of medicinal chemistry 2020 Mar 1;189:112076
Nbr1-regulated autophagy in Lactoferrin-induced osteoblastic differentiation.
Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1191-1200
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Arsenic induces dysfunctional autophagy via dual regulation of mTOR pathway and Beclin1-Vps34/PI3K complex in MLTC-1 cells.
Liang C, Feng Z, Manthari RK, Wang C, Han Y, Fu W, Wang J, Zhang J
Journal of hazardous materials 2020 Jun 5;391:122227
Journal of hazardous materials 2020 Jun 5;391:122227
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro.
Tan Y, Yin L, Sun Z, Shao S, Chen W, Man X, Du Y, Chen Y
International journal of biological macromolecules 2020 Jun 15;153:349-356
International journal of biological macromolecules 2020 Jun 15;153:349-356
Calcitriol decreases live Porphyromonas gingivalis internalized into epithelial cells and monocytes by promoting autophagy.
Hu X, Niu L, Ma C, Huang Y, Yang X, Shi Y, Pan C, Liu J, Wang H, Li Q, Geng F, Tang X
Journal of periodontology 2020 Jul;91(7):956-966
Journal of periodontology 2020 Jul;91(7):956-966
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, Li S, Zhang J, Dai W, Xu X, Mao Y, Xu S, Chen K, Li J, Guo C
International immunopharmacology 2020 Jul;84:106529
International immunopharmacology 2020 Jul;84:106529
The Effect of Autophagic Activity on the Function of Apheresis Platelets and on the Efficacy of Clinical Platelet Transfusion.
Tang H, Gao M, Fu Y, Gui R, Ma X
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2020 Jul;47(4):302-313
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2020 Jul;47(4):302-313
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy.
Yang Y, Liao Y, Gui YP, Zhao L, Guo LB
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Chinese journal of natural medicines 2020 Jul;18(7):491-499
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway.
Mei ZG, Huang YG, Feng ZT, Luo YN, Yang SB, Du LP, Jiang K, Liu XL, Fu XY, Deng YH, Zhou HJ
Aging 2020 Jul 3;12(13):13187-13205
Aging 2020 Jul 3;12(13):13187-13205
Aldehyde dehydrogenase 2 regulates autophagy via the Akt-mTOR pathway to mitigate renal ischemia-reperfusion injury in hypothermic machine perfusion.
Lin D, Xiang T, Qiu Q, Leung J, Xu J, Zhou W, Hu Q, Lan J, Liu Z, Zhong Z, Wang Y, Ye Q
Life sciences 2020 Jul 15;253:117705
Life sciences 2020 Jul 15;253:117705
Methylmercury disrupts autophagic flux by inhibiting autophagosome-lysosome fusion in mouse germ cells.
Chen N, Tang X, Ye Z, Wang S, Xiao X
Ecotoxicology and environmental safety 2020 Jul 15;198:110667
Ecotoxicology and environmental safety 2020 Jul 15;198:110667
Melatonin alleviates defects induced by zearalenone during porcine embryo development.
Yao X, Jiang H, Gao Q, Li YH, Xu YN, Kim NH
Theriogenology 2020 Jul 15;151:66-73
Theriogenology 2020 Jul 15;151:66-73
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.
Xiang Q, Wan P, Yang G, Huang S, Qin M, Yang H, Luo Z, Wu K, Wu J
Viruses 2020 Jul 14;12(7)
Viruses 2020 Jul 14;12(7)
Cells deficient for Krüppel-like factor 4 exhibit mitochondrial dysfunction and impaired mitophagy.
Rosencrans WM, Walsh ZH, Houerbi N, Blum A, Belew M, Liu C, Chernak B, Brauer PR, Trazo A, Olson A, Hagos E
European journal of cell biology 2020 Jan;99(1):151061
European journal of cell biology 2020 Jan;99(1):151061
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, He G, Han B
Cell proliferation 2020 Jan;53(1):e12701
Cell proliferation 2020 Jan;53(1):e12701
14-3-3ζ binds to and stabilizes phospho-beclin 1(S295) and induces autophagy in hepatocellular carcinoma cells.
Tang Y, Zhang Y, Liu S, Sun Z, Wang C, Li L, Zhou W, Cheng S
Journal of cellular and molecular medicine 2020 Jan;24(1):954-964
Journal of cellular and molecular medicine 2020 Jan;24(1):954-964
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Liu Y, Fan D
Nutrients 2020 Jan 18;12(1)
Nutrients 2020 Jan 18;12(1)
Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro.
Hu Z, Pan Y, Cheng A, Zhang X, Wang M, Chen S, Zhu D, Liu M, Yang Q, Wu Y, Zhao X, Huang J, Zhang S, Mao S, Ou X, Yu Y, Zhang L, Liu Y, Tian B, Pan L, Rehman MU, Yin Z, Jia R
Vaccines 2020 Jan 13;8(1)
Vaccines 2020 Jan 13;8(1)
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Zhang W, Zhu T, Chen L, Luo W, Chao J
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway.
Xu J, Deng Y, Wang Y, Sun X, Chen S, Fu G
Cell proliferation 2020 Feb;53(2):e12738
Cell proliferation 2020 Feb;53(2):e12738
Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway.
Chen M, Zhu LL, Su JL, Li GL, Wang J, Zhang YN
Human & experimental toxicology 2020 Feb;39(2):173-181
Human & experimental toxicology 2020 Feb;39(2):173-181
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
You B, Dun Y, Zhang W, Jiang L, Li H, Xie M, Liu Y, Liu S
The Journal of endocrinology 2020 Feb;244(2):383-393
The Journal of endocrinology 2020 Feb;244(2):383-393
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
Hu LD, Wang J, Chen XJ, Yan YB
Biochimica et biophysica acta. Molecular cell research 2020 Feb;1867(2):118617
Biochimica et biophysica acta. Molecular cell research 2020 Feb;1867(2):118617
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358
Oncology letters 2020 Dec;20(6):358
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells.
Xu J, Wang Z, Huang Y, Wang Y, Xiang L, He X
Steroids 2020 Dec;164:108737
Steroids 2020 Dec;164:108737
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
You L, Chen J, Liu W, Xiang Q, Luo Z, Wang W, Xu W, Wu K, Zhang Q, Liu Y, Wu J
Virulence 2020 Dec;11(1):537-553
Virulence 2020 Dec;11(1):537-553
Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model.
Huang HT, Cheng TL, Ho CJ, Huang HH, Lu CC, Chuang SC, Li JY, Lee TC, Chen ST, Lin YS, Lee CY, Kang L, Lin SY, Chen CH
Antioxidants (Basel, Switzerland) 2020 Dec 23;10(1)
Antioxidants (Basel, Switzerland) 2020 Dec 23;10(1)
Potential therapeutic role of fibroblast growth factor 21 in neurodegeneration: Evidence for ameliorating parkinsonism via silent information regulator 2 homolog 1 and implication for gene therapy.
Chen Y, Shen J, Qi G, Zha Q, Zhang C, Yao W, Gao X, Chen S
Neuropharmacology 2020 Dec 15;181:108335
Neuropharmacology 2020 Dec 15;181:108335
CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway.
Li L, Xie P, Lin W, Liu J, Chen J, Guo Z, Bin C, An W, Zhang C, Zhan Y
Experimental cell research 2020 Dec 1;397(1):112341
Experimental cell research 2020 Dec 1;397(1):112341
Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes.
Zhang Y, Cai W, Han G, Zhou S, Li J, Chen M, Li H
International journal of molecular medicine 2020 Apr;45(4):1225-1236
International journal of molecular medicine 2020 Apr;45(4):1225-1236
Toll-Like Receptor 2-Mediated Autophagy Promotes Microglial Cell Death by Modulating the Microglial M1/M2 Phenotype.
Ma K, Guo J, Wang G, Ni Q, Liu X
Inflammation 2020 Apr;43(2):701-711
Inflammation 2020 Apr;43(2):701-711
Organic anion transporters and PI3K-AKT-mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein.
Bu T, Wang C, Jin H, Meng Q, Huo X, Sun H, Sun P, Wu J, Ma X, Liu Z, Liu K
Journal of cellular physiology 2020 Apr;235(4):3309-3319
Journal of cellular physiology 2020 Apr;235(4):3309-3319
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis.
Shi B, Huang Y, Ni J, Chen J, Wei J, Gao H, Li L, Zhou Z, Wang Y, Xu Y, Xu Z, Mao J, Fan G
Scientific reports 2020 Apr 8;10(1):6105
Scientific reports 2020 Apr 8;10(1):6105
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Wang N, Xu F, Lu S, Zhang N, Sun Y
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.
Chen HX, Liang FC, Gu P, Xu BL, Xu HJ, Wang WT, Hou JY, Xie DX, Chai XQ, An SJ
Cell death & disease 2020 Apr 27;11(4):288
Cell death & disease 2020 Apr 27;11(4):288
CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Li S, Hao M, Li B, Chen M, Chen J, Tang J, Hong S, Min J, Hu M, Hong L
Cell death & disease 2020 Apr 24;11(4):279
Cell death & disease 2020 Apr 24;11(4):279
Autophagy impairment contributes to PBDE-47-induced developmental neurotoxicity and its relationship with apoptosis.
Li P, Ma R, Dong L, Liu L, Zhou G, Tian Z, Zhao Q, Xia T, Zhang S, Wang A
Theranostics 2019;9(15):4375-4390
Theranostics 2019;9(15):4375-4390
Excessive Methionine Supplementation Exacerbates the Development of Abdominal Aortic Aneurysm in Rats.
Fan Y, Li N, Liu C, Dong H, Hu X
Journal of vascular research 2019;56(5):230-240
Journal of vascular research 2019;56(5):230-240
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA.
Sun Y, Li C, Feng J, Li Y, Zhai X, Zhang L, Li C
Oxidative medicine and cellular longevity 2019;2019:8753413
Oxidative medicine and cellular longevity 2019;2019:8753413
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, Han Y, Deng J, Zhou Y
Mediators of inflammation 2019;2019:6175091
Mediators of inflammation 2019;2019:6175091
Prevention of Huntington's Disease-Like Behavioral Deficits in R6/1 Mouse by Tolfenamic Acid Is Associated with Decreases in Mutant Huntingtin and Oxidative Stress.
Liu P, Li Y, Yang W, Liu D, Ji X, Chi T, Guo Z, Li L, Zou L
Oxidative medicine and cellular longevity 2019;2019:4032428
Oxidative medicine and cellular longevity 2019;2019:4032428
Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy.
Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, Li S, Feng J, Liu T, Zhang J, Chen J, Zhou Y, Mao Y, Wang F, Dai W, Fan X, Guo C, Wu J
Mediators of inflammation 2019;2019:3240713
Mediators of inflammation 2019;2019:3240713
Leucine-rich repeat and sterile alpha motif containing 1 promotes the oncogenic growth of human hepatocellular carcinoma cells.
Pian L, Huang X, Zhao M, Zhang Y, Qin C, Zhang J, Zhang J, Wang Q
Cancer cell international 2019;19:255
Cancer cell international 2019;19:255
FePt/GO Nanosheets Suppress Proliferation, Enhance Radiosensitization and Induce Autophagy of Human Non-Small Cell Lung Cancer Cells.
Ma S, Miao H, Luo Y, Sun Y, Tian X, Wang F, You C, Peng S, Tang G, Yang C, Sun W, Li S, Mao Y, Xu J, Xiao Y, Gong Y, Quan H, Xie C
International journal of biological sciences 2019;15(5):999-1009
International journal of biological sciences 2019;15(5):999-1009
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
Rutin suppresses FNDC1 expression in bone marrow mesenchymal stem cells to inhibit postmenopausal osteoporosis.
Xiao Y, Wei R, Yuan Z, Lan X, Kuang J, Hu D, Song Y, Luo J
American journal of translational research 2019;11(10):6680-6690
American journal of translational research 2019;11(10):6680-6690
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats.
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R
Frontiers in physiology 2019;10:735
Frontiers in physiology 2019;10:735
Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.
Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, Cai D, Rui J, Zhang L
Frontiers in pharmacology 2019;10:676
Frontiers in pharmacology 2019;10:676
Transmembrane Protein 39A Promotes the Replication of Encephalomyocarditis Virus via Autophagy Pathway.
Li X, Ma R, Li Q, Li S, Zhang H, Xie J, Bai J, Idris A, Feng R
Frontiers in microbiology 2019;10:2680
Frontiers in microbiology 2019;10:2680
Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin.
Zhang S, Zhou L, Zhang M, Wang Y, Wang M, Du J, Gu W, Kui F, Li J, Geng S, Du G
Frontiers in pharmacology 2019;10:1658
Frontiers in pharmacology 2019;10:1658
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W
Frontiers in pharmacology 2019;10:1238
Frontiers in pharmacology 2019;10:1238
Rapamycin attenuates articular cartilage degeneration by inhibiting β-catenin in a murine model of osteoarthritis.
Ma L, Liu Y, Zhao X, Li P, Jin Q
Connective tissue research 2019 Sep;60(5):452-462
Connective tissue research 2019 Sep;60(5):452-462
Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.
Nian FS, Li LL, Cheng CY, Wu PC, Lin YT, Tang CY, Ren BS, Tai CY, Fann MJ, Kao LS, Hong CJ, Tsai JW
Molecular neurobiology 2019 Sep;56(9):6095-6105
Molecular neurobiology 2019 Sep;56(9):6095-6105
The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.
Zhang X, Bu H, Jiang Y, Sun G, Jiang R, Huang X, Duan H, Huang Z, Wu Q
Molecular medicine reports 2019 Sep;20(3):2867-2874
Molecular medicine reports 2019 Sep;20(3):2867-2874
Protective role of thymoquinone in sepsis-induced liver injury in BALB/c mice.
Wang F, Lei X, Zhao Y, Yu Q, Li Q, Zhao H, Pei Z
Experimental and therapeutic medicine 2019 Sep;18(3):1985-1992
Experimental and therapeutic medicine 2019 Sep;18(3):1985-1992
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, Lian S
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.
Zhou G, Tang S, Yang L, Niu Q, Chen J, Xia T, Wang S, Wang M, Zhao Q, Liu L, Li P, Dong L, Yang K, Zhang S, Wang A
Toxicology and applied pharmacology 2019 Sep 1;378:114608
Toxicology and applied pharmacology 2019 Sep 1;378:114608
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
Xu WN, Yang RZ, Zheng HL, Yu W, Zheng XF, Li B, Jiang SD, Jiang LS
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
International journal of biological macromolecules 2019 Sep 1;136:1007-1017
Orientin Improves Cognition by Enhancing Autophagosome Clearance in an Alzheimer's Mouse Model.
Zhong Y, Zheng QY, Sun CY, Zhang Z, Han K, Jia N
Journal of molecular neuroscience : MN 2019 Oct;69(2):246-253
Journal of molecular neuroscience : MN 2019 Oct;69(2):246-253
Neuroprotective effect of Verbascoside on hypoxic-ischemic brain damage in neonatal rat.
Wei W, Lu M, Lan X, Liu N, Wang H, Du J, Sun T, Li Y, Yu J
Neuroscience letters 2019 Oct 15;711:134415
Neuroscience letters 2019 Oct 15;711:134415
Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma.
Chan KK, Wong ES, Wong IT, Cheung CL, Wong OG, Ngan HY, Cheung AN
BMC cancer 2019 Oct 15;19(1):953
BMC cancer 2019 Oct 15;19(1):953
Enhancing autophagy by down-regulating GSK-3β alleviates cisplatin-induced ototoxicity in vivo and in vitro.
Liu T, Zong S, Luo P, Qu Y, Wen Y, Du P, Xiao H
Toxicology letters 2019 Oct 1;313:11-18
Toxicology letters 2019 Oct 1;313:11-18
B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.
Yu S, Wang X, Dou N, Zhou J, Gao Y, Li Y
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Nov;49(11):1329-1340
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Nov;49(11):1329-1340
Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.
Kuang M, Li L, Li C, Wang G
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Cell stress & chaperones 2019 Nov;24(6):1115-1125
Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.
Li R, Du J, Yao Y, Yao G, Wang X
Journal of cellular physiology 2019 Nov;234(11):20566-20576
Journal of cellular physiology 2019 Nov;234(11):20566-20576
Iron dysregulation in vascular dementia: Focused on the AMPK/autophagy pathway.
Huo T, Jia Y, Yin C, Luo X, Zhao J, Wang Z, Lv P
Brain research bulletin 2019 Nov;153:305-313
Brain research bulletin 2019 Nov;153:305-313
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL 3rd, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB
Acta neuropathologica 2019 Nov;138(5):795-811
Acta neuropathologica 2019 Nov;138(5):795-811
Downregulation of microRNA-30a-5p contributes to the replication of duck enteritis virus by regulating Beclin-1-mediated autophagy.
Wu X, Jia R, Wang M, Chen S, Liu M, Zhu D, Zhao X, Yang Q, Wu Y, Yin Z, Zhang S, Huang J, Zhang L, Liu Y, Yu Y, Pan L, Tian B, Rehman MU, Chen X, Cheng A
Virology journal 2019 Nov 26;16(1):144
Virology journal 2019 Nov 26;16(1):144
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, Fan X, Guo C, Wu J
International immunopharmacology 2019 May;70:435-445
International immunopharmacology 2019 May;70:435-445
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC
Autophagy 2019 May;15(5):827-842
Autophagy 2019 May;15(5):827-842
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, Jiang Q
Food & function 2019 May 22;10(5):2651-2657
Food & function 2019 May 22;10(5):2651-2657
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Zhao Q, Niu Q, Chen J, Xia T, Zhou G, Li P, Dong L, Xu C, Tian Z, Luo C, Liu L, Zhang S, Wang A
Archives of toxicology 2019 Mar;93(3):709-726
Archives of toxicology 2019 Mar;93(3):709-726
Fibroblast growth factor-21 alleviates hypoxia/reoxygenation injury in H9c2 cardiomyocytes by promoting autophagic flux.
Ren Z, Xiao W, Zeng Y, Liu MH, Li GH, Tang ZH, Qu SL, Hao YM, Yuan HQ, Jiang ZS
International journal of molecular medicine 2019 Mar;43(3):1321-1330
International journal of molecular medicine 2019 Mar;43(3):1321-1330
Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy.
Hou JZ, Xi ZQ, Niu J, Li W, Wang X, Liang C, Sun H, Fang D, Xie SQ
Oncology reports 2019 Mar;41(3):1971-1979
Oncology reports 2019 Mar;41(3):1971-1979
2,3',4,4',5-Pentachlorobiphenyl induced autophagy of the thyrocytes via DAPK2/PKD/VPS34 pathway.
Zhou Q, Wang L, Chen H, Xu B, Xu W, Sheng Y, Duan Y
Archives of toxicology 2019 Jun;93(6):1639-1648
Archives of toxicology 2019 Jun;93(6):1639-1648
Drp1-associated mitochondrial dysfunction and mitochondrial autophagy: a novel mechanism in triptolide-induced hepatotoxicity.
Hasnat M, Yuan Z, Naveed M, Khan A, Raza F, Xu D, Ullah A, Sun L, Zhang L, Jiang Z
Cell biology and toxicology 2019 Jun;35(3):267-280
Cell biology and toxicology 2019 Jun;35(3):267-280
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
Wu J, Kuang L, Chen C, Yang J, Zeng WN, Li T, Chen H, Huang S, Fu Z, Li J, Liu R, Ni Z, Chen L, Yang L
Biomaterials 2019 Jun;206:87-100
Biomaterials 2019 Jun;206:87-100
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells.
Cui C, Li Z, Wu D
Biological research 2019 Jun 13;52(1):32
Biological research 2019 Jun 13;52(1):32
Nonstructural Protein NP1 of Human Bocavirus 1 suppresses the growth of A549 cell by promoting autophagy.
Zhu J, Li J, Wang X, Feng X, Li Y
The new microbiologica 2019 Jul;42(3):161-165
The new microbiologica 2019 Jul;42(3):161-165
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Xu G, Wang X, Yu H, Wang C, Liu Y, Zhao R, Zhang G
Human & experimental toxicology 2019 Jul;38(7):794-802
Human & experimental toxicology 2019 Jul;38(7):794-802
STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy.
Du W, Wang N, Li F, Jia K, An J, Liu Y, Wang Y, Zhu L, Zhao S, Hao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8008-8021
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Yin F, Yan J, Zhao Y, Guo KJ, Zhang ZL, Li AP, Meng CY, Guo L
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
Ecotoxicology and environmental safety 2019 Jul 30;176:234-241
MicroRNA-101 regulates autophagy, proliferation and apoptosis via targeting EZH2 in laryngeal squamous cell carcinoma.
Chen L, Jia J, Zang Y, Li J, Wan B
Neoplasma 2019 Jul 23;66(4):507-515
Neoplasma 2019 Jul 23;66(4):507-515
Exogenous hydrogen sulfide mitigates NLRP3 inflammasome-mediated inflammation through promoting autophagy via the AMPK-mTOR pathway.
Wang H, Zhong P, Sun L
Biology open 2019 Jul 17;8(7)
Biology open 2019 Jul 17;8(7)
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, Zhang J, Huang S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells.
Zhang Z, Zhang M, Liu H, Yin W
Journal of cellular biochemistry 2019 Jan;120(1):756-767
Journal of cellular biochemistry 2019 Jan;120(1):756-767
Melatonin protects against sepsis-induced cardiac dysfunction by regulating apoptosis and autophagy via activation of SIRT1 in mice.
Zhang WX, He BM, Wu Y, Qiao JF, Peng ZY
Life sciences 2019 Jan 15;217:8-15
Life sciences 2019 Jan 15;217:8-15
Effects of Fluoride on Autophagy in Mouse Sertoli Cells.
Feng Z, Liang C, Manthari RK, Wang C, Zhang J
Biological trace element research 2019 Feb;187(2):499-505
Biological trace element research 2019 Feb;187(2):499-505
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation.
Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
Yonsei medical journal 2019 Dec;60(12):1195-1202
Yonsei medical journal 2019 Dec;60(12):1195-1202
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2.
Li N, Guo X, Liu L, Wang L, Cheng R
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2529-2535
Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.
Bao H, Zhang Q, Liu X, Song Y, Li X, Wang Z, Li C, Peng A, Gong R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14370-14381
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14370-14381
Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2.
Wang R, Liu H, Shao Y, Wang K, Yin S, Qiu Y, Wu H, Liu E, Wang T, Gao X, Yu H
Molecular cancer research : MCR 2019 Dec;17(12):2469-2479
Molecular cancer research : MCR 2019 Dec;17(12):2469-2479
XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Wang N, Yang B, Muhetaer G, Wang S, Zheng Y, Lu J, Li M, Zhang F, Situ H, Lin Y, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109519
Conditioned medium obtained from human amniotic mesenchymal stem cells attenuates focal cerebral ischemia/reperfusion injury in rats by targeting mTOR pathway.
Nazarinia D, Aboutaleb N, Gholamzadeh R, Nasseri Maleki S, Mokhtari B, Nikougoftar M
Journal of chemical neuroanatomy 2019 Dec;102:101707
Journal of chemical neuroanatomy 2019 Dec;102:101707
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Wang L, Huang W, Zhan J
Nutrients 2019 Dec 6;11(12)
Nutrients 2019 Dec 6;11(12)
Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway.
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF, Yang JL, Mao QS, Xue WJ
Experimental cell research 2019 Dec 15;385(2):111691
Experimental cell research 2019 Dec 15;385(2):111691
HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA.
Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, Feng J
Life sciences 2019 Dec 15;239:117020
Life sciences 2019 Dec 15;239:117020
Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice.
Wu XT, Ansari AR, Pang XX, Li HZ, Zhang ZW, Luo Y, Arshad M, Song H
Archivum immunologiae et therapiae experimentalis 2019 Aug;67(4):249-261
Archivum immunologiae et therapiae experimentalis 2019 Aug;67(4):249-261
Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy.
Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, Chen W, Gui R
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
ACS applied materials & interfaces 2019 Aug 7;11(31):28254-28266
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
Barot S, Abo-Ali EM, Zhou DL, Palaguachi C, Dukhande VV
Experimental cell research 2019 Aug 15;381(2):288-300
Experimental cell research 2019 Aug 15;381(2):288-300
Hexabromocyclododecanes promoted autophagy through the PI3K/Akt/mTOR pathway in L02 cells.
Jin Y, Shang Y, Zhang D, An J, Pan D
Journal of environmental management 2019 Aug 15;244:77-82
Journal of environmental management 2019 Aug 15;244:77-82
Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells.
Gao L, Wang Z, Lu D, Huang J, Liu J, Hong L
Cell death & disease 2019 Aug 13;10(8):609
Cell death & disease 2019 Aug 13;10(8):609
Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage.
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, Sun H, Qi Y, Fang L, Liu K, Peng J
British journal of pharmacology 2019 Apr;176(7):919-937
British journal of pharmacology 2019 Apr;176(7):919-937
Silver nanoparticles induce protective autophagy via Ca(2+)/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains.
Li L, Li L, Zhou X, Yu Y, Li Z, Zuo D, Wu Y
Nanotoxicology 2019 Apr;13(3):369-391
Nanotoxicology 2019 Apr;13(3):369-391
β-Arrestin2 Inhibits Expression of Inflammatory Cytokines in BEAS-2B Lung Epithelial Cells Treated with Cigarette Smoke Condensate via Inhibition of Autophagy.
Wu Y, Li Y, Wu B, Tan C, He X, Xu B, Yu G, Wang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1270-1285
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1270-1285
Xiaoqinglong Decoction Attenuates Chronic Obstructive Pulmonary Disease in Rats via Inhibition of Autophagy.
Wang H, Mao B, Chen C
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6705871
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6705871
Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation.
Huang T, Sun Y, Li Y, Wang T, Fu Y, Li C, Li C
Oxidative medicine and cellular longevity 2018;2018:4928703
Oxidative medicine and cellular longevity 2018;2018:4928703
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, Chen K, Xia Y, Niu P, Xu L, Wang F, Dai W, Zhou Y, Guo C
Mediators of inflammation 2018;2018:4032484
Mediators of inflammation 2018;2018:4032484
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, Niu P
PPAR research 2018;2018:3180396
PPAR research 2018;2018:3180396
Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy.
Sun RZ, Fan Y, Liang X, Gong TT, Wang Q, Liu H, Shan ZY, Lei L
BioMed research international 2018;2018:1010248
BioMed research international 2018;2018:1010248
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways.
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, Lv Y, Liu Q, Guo C, Zhou Y
Drug design, development and therapy 2018;12:4067-4082
Drug design, development and therapy 2018;12:4067-4082
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
Zhang XR, Wang SY, Sun W, Wei C
Molecular medicine reports 2018 Sep;18(3):3429-3436
Molecular medicine reports 2018 Sep;18(3):3429-3436
Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy.
Liang S, Jin J, Shen X, Jiang X, Li Y, He Q
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Experimental and therapeutic medicine 2018 Sep;16(3):2275-2280
Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma.
Chan KK, Wong OG, Wong ES, Chan KK, Ip PP, Tse KY, Cheung AN
International journal of cancer 2018 Sep 15;143(6):1456-1469
International journal of cancer 2018 Sep 15;143(6):1456-1469
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells.
Wu Y, Li Y, Wang B, He X, Li Y, Wu B, Yu G, Wang H, Xu B
Life sciences 2018 Oct 15;211:270-278
Life sciences 2018 Oct 15;211:270-278
Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes.
Zhao Y, Li Y, Wang J, Manthari RK, Wang J
Archives of toxicology 2018 Nov;92(11):3277-3289
Archives of toxicology 2018 Nov;92(11):3277-3289
Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins.
Manthari RK, Tikka C, Ommati MM, Niu R, Sun Z, Wang J, Zhang J, Wang J
Archives of toxicology 2018 Nov;92(11):3255-3275
Archives of toxicology 2018 Nov;92(11):3255-3275
Protective effects of α‑2‑macroglobulin on human bone marrow mesenchymal stem cells in radiation injury.
Liu Y, Cao W, Kong X, Li J, Chen X, Ge Y, Zhong W, Fang S
Molecular medicine reports 2018 Nov;18(5):4219-4228
Molecular medicine reports 2018 Nov;18(5):4219-4228
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells.
Guo S, Liang X, Guo M, Zhang X, Li Z
International journal of biological macromolecules 2018 Nov;119:669-676
International journal of biological macromolecules 2018 Nov;119:669-676
Mutant UBQLN2(P497H) in motor neurons leads to ALS-like phenotypes and defective autophagy in rats.
Chen T, Huang B, Shi X, Gao L, Huang C
Acta neuropathologica communications 2018 Nov 8;6(1):122
Acta neuropathologica communications 2018 Nov 8;6(1):122
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
Cantharidin suppresses cell growth and migration, and activates autophagy in human non-small cell lung cancer cells.
Liu YP, Li L, Xu L, Dai EN, Chen WD
Oncology letters 2018 May;15(5):6527-6532
Oncology letters 2018 May;15(5):6527-6532
Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish.
Chen T, Song G, Yang H, Mao L, Cui Z, Huang K
Genetics 2018 Mar;208(3):1131-1146
Genetics 2018 Mar;208(3):1131-1146
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Oxidative stress-mediated autophagic cell death participates in the neurotoxic effect on SH-SY5Y cells induced by excessive iodide.
Liu H, Wang L, Zeng Q, Zhao L, Cui Y, Hou C, Zhang B, Zhang Z, Zhang S, Chen X, Wang A
Environmental toxicology 2018 Jun 19;
Environmental toxicology 2018 Jun 19;
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Peroxisome Proliferator-Activated Receptor (PPARγ) Plays a Protective Role in Cigarette Smoking-Induced Inflammation via AMP-Activated Protein Kinase (AMPK) Signaling.
Wang L, Yin Y, Hou G, Kang J, Wang Q
Medical science monitor : international medical journal of experimental and clinical research 2018 Jul 25;24:5168-5177
Medical science monitor : international medical journal of experimental and clinical research 2018 Jul 25;24:5168-5177
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy.
Wei W, An XR, Jin SJ, Li XX, Xu M
Scientific reports 2018 Jan 8;8(1):9
Scientific reports 2018 Jan 8;8(1):9
Autophagy participates in innate immune defense in lamprey.
Luo L, Lu J, Wang Q, Chen S, Xu A, Yuan S
Fish & shellfish immunology 2018 Dec;83:416-424
Fish & shellfish immunology 2018 Dec;83:416-424
The Role of SIRT1 in Autophagy in Lipopolysaccharide-Induced Mouse Type II Alveolar Epithelial Cells.
Liu J, Lv X, Dong W, Hu M, Xu J, Qian G, Li Y
Inflammation 2018 Dec;41(6):2222-2235
Inflammation 2018 Dec;41(6):2222-2235
Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer.
Wu JS, Li L, Wang SS, Pang X, Wu JB, Sheng SR, Tang YJ, Tang YL, Zheng M, Liang XH
Oncology reports 2018 Dec;40(6):3381-3391
Oncology reports 2018 Dec;40(6):3381-3391
Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice.
Shi GJ, Zheng J, Han XX, Jiang YP, Li ZM, Wu J, Chang Q, Niu Y, Sun T, Li YX, Chen Z, Yu JQ
Cell and tissue research 2018 Dec;374(3):653-666
Cell and tissue research 2018 Dec;374(3):653-666
Modulation of autophagy in the protective effect of resveratrol on PM2.5-induced pulmonary oxidative injury in mice.
Li Y, Fu S, Li E, Sun X, Xu H, Meng Y, Wang X, Chen Y, Xie C, Geng S, Wu J, Zhong C, Xu P
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Phytotherapy research : PTR 2018 Dec;32(12):2480-2486
Gli2 modulates cell cycle re-entry through autophagy-mediated regulation of the length of primary cilia.
Hsiao CJ, Chang CH, Ibrahim RB, Lin IH, Wang CH, Wang WJ, Tsai JW
Journal of cell science 2018 Dec 17;131(24)
Journal of cell science 2018 Dec 17;131(24)
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S
The Science of the total environment 2018 Dec 15;645:363-371
The Science of the total environment 2018 Dec 15;645:363-371
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
Interplay of Autophagy Inducer Rapamycin and Proteasome Inhibitor MG132 in Reduction of Foam Cell Formation and Inflammatory Cytokine Expression.
Zhang W, Xu W, Chen W, Zhou Q
Cell transplantation 2018 Aug;27(8):1235-1248
Cell transplantation 2018 Aug;27(8):1235-1248
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.
Ji J, Xue TF, Guo XD, Yang J, Guo RB, Wang J, Huang JY, Zhao XJ, Sun XL
Aging cell 2018 Aug;17(4):e12774
Aging cell 2018 Aug;17(4):e12774
Autophagy is required for proper meiosis of porcine oocytes maturing in vitro.
Shen XH, Jin YX, Liang S, Kwon JW, Zhu JW, Lei L, Kim NH
Scientific reports 2018 Aug 22;8(1):12581
Scientific reports 2018 Aug 22;8(1):12581
Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway.
Manthari RK, Tikka C, Ommati MM, Niu R, Sun Z, Wang J, Zhang J, Wang J
Journal of agricultural and food chemistry 2018 Aug 15;66(32):8602-8614
Journal of agricultural and food chemistry 2018 Aug 15;66(32):8602-8614
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Dai C, Ciccotosto GD, Cappai R, Wang Y, Tang S, Hoyer D, Schneider EK, Velkov T, Xiao X
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Dun Y, Liu S, Zhang W, Xie M, Qiu L
Oxidative medicine and cellular longevity 2017;2017:8024857
Oxidative medicine and cellular longevity 2017;2017:8024857
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Zhao Z, Zhang L, Guo XD, Cao LL, Xue TF, Zhao XJ, Yang DD, Yang J, Ji J, Huang JY, Sun XL
Frontiers in molecular neuroscience 2017;10:293
Frontiers in molecular neuroscience 2017;10:293
Resveratrol prevents the combined maternal plus postweaning high-fat-diets-induced hypertension in male offspring.
Tain YL, Lin YJ, Sheen JM, Lin IC, Yu HR, Huang LT, Hsu CN
The Journal of nutritional biochemistry 2017 Oct;48:120-127
The Journal of nutritional biochemistry 2017 Oct;48:120-127
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer.
Yang YH, Liu JB, Gui Y, Lei LL, Zhang SJ
World journal of gastroenterology 2017 Oct 28;23(40):7232-7241
World journal of gastroenterology 2017 Oct 28;23(40):7232-7241
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Wang K, Li S, Worku T, Hao X, Yang L, Zhang S
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, Zheng H, Eng M, Wang J
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
Levels of Leydig cell autophagy regulate the fertility of male naked mole-rats.
Yang W, Li L, Huang X, Kan G, Lin L, Cheng J, Xu C, Sun W, Cong W, Zhao S, Cui S
Oncotarget 2017 Nov 17;8(58):98677-98690
Oncotarget 2017 Nov 17;8(58):98677-98690
Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells.
Park S, Choi Y, Jung N, Kim J, Oh S, Yu Y, Ahn JH, Jo I, Choi BO, Jung SC
International journal of molecular medicine 2017 Apr;39(4):831-840
International journal of molecular medicine 2017 Apr;39(4):831-840
Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy.
Chen T, Ren H, Thakur A, Yang T, Li Y, Zhang S, Wang T, Chen M
DNA and cell biology 2016 Dec;35(12):751-757
DNA and cell biology 2016 Dec;35(12):751-757
Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells.
Pan Y, Bai J, Shen F, Sun L, He Q, Su B
Molecular medicine reports 2016 Aug;14(2):1751-5
Molecular medicine reports 2016 Aug;14(2):1751-5
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells.
Deng X, Zhang F, Rui W, Long F, Wang L, Feng Z, Chen D, Ding W
Toxicology in vitro : an international journal published in association with BIBRA 2013 Sep;27(6):1762-70
Toxicology in vitro : an international journal published in association with BIBRA 2013 Sep;27(6):1762-70
Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis.
Wei DH, Jia XY, Liu YH, Guo FX, Tang ZH, Li XH, Wang Z, Liu LS, Wang GX, Jian ZS, Ruan CG
International journal of molecular medicine 2013 Feb;31(2):400-6
International journal of molecular medicine 2013 Feb;31(2):400-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14600-1-AP(LC3 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LC3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LC3. This antibody recognizes human, mouse, rat antigen. The LC3 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14600-1-AP(LC3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14600-1-AP(LC3 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
