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- References [289]
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- Product number
- 18725-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18725-1-AP, RRID:AB_2137745
- Product name
- LC3B-Specific antibody
- Antibody type
- Polyclonal
- Description
- LC3B-Specific antibody (Cat. #18725-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling.
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Autophagy plays a pro-apoptotic role in arsenic trioxide-induced cell death of liver cancer.
Selenomethionine preconditioned mesenchymal stem cells derived extracellular vesicles exert enhanced therapeutic efficacy in intervertebral disc degeneration.
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy.
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Response of lipid metabolism, energy supply, and cell fate in yellowstripe goby (Mugilogobius chulae) exposed to environmentally relevant concentrations atorvastatin.
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
L-Alanine promotes anti-infectious properties of Bacillus subtilis S-2 spores via the germination receptor gerAA.
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway.
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Toosendanin induces hepatotoxicity by restraining autophagy and lysosomal function through inhibiting STAT3/CTSC axis.
PRRSV degrades MDA5 via dual autophagy receptors P62 and CCT2 to evade antiviral innate immunity.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Mitophagy activation by rapamycin enhances mitochondrial function and cognition in 5×FAD mice.
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Metabolic reprogramming induced by DCA enhances cisplatin sensitivity through increasing mitochondrial oxidative stress in cholangiocarcinoma.
PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling.
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor α deficiency, associated with decreased ERK and Akt activation.
Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells.
Targeted Degradation of Alpha-Synuclein by Autophagosome-Anchoring Chimera Peptides.
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Galectin-7 promotes cisplatin efficacy by facilitating apoptosis and G3BP1 degradation in cervical cancer.
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
The master antioxidant defense is activated during EBV latent infection.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
O-GlcNAcylation regulates OTX2's proteostasis.
Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no-reflow.
MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.
PDK1 inhibition reduces autophagy and cell senescence through the PI3K/AKT signalling pathway in a cigarette smoke mouse emphysema model.
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression.
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Optic nerve injury models under varying forces.
MiR-141-3p promotes hypoxia-induced autophagy in human placental trophoblast cells.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Autophagy gene Atg7 regulates the development of radiation-induced skin injury and fibrosis of skin.
Mitochondrial damage-induced abnormal glucose metabolism with ageing in the hippocampus of APP/PS1 mice.
Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis.
LncRNA MEG3 regulates ASK1/JNK axis-mediated apoptosis and autophagy via sponging miR-23a in granulosa cells of yak tertiary follicles.
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Hydrogen sulfide inhibits human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG4B.
Induction of autophagy via the PI3K/Akt/mTOR signaling pathway by Pueraria flavonoids improves non-alcoholic fatty liver disease in obese mice.
Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
FUNDC1/PFKP-mediated mitophagy induced by KD025 ameliorates cartilage degeneration in osteoarthritis.
Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity.
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma.
Blockade of CXCR4 promotes macrophage autophagy through the PI3K/AKT/mTOR pathway to alleviate coronary heart disease.
Mitophagy-dependent cardioprotection of resistance training on heart failure.
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Melatonin inhibits atherosclerosis progression via galectin-3 downregulation to enhance autophagy and inhibit inflammation.
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Plasminogen decreases Aβ42 and Tau deposition, and shows multi-beneficial effects on Alzheimer's disease in mice and humans.
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Ethyl Extract of Blaps rynchopetera Fairmaire Ameliorates Experimental Aerobic Vaginitis by Inhibiting Autophagy Activation.
The Role of Autophagy in Lamellar Body Formation and Surfactant Production in Type 2 Alveolar Epithelial Cells.
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway.
Moxidectin induces autophagy arrest in colorectal cancer.
Activation of Autophagy Induces Monocrotaline-Induced Pulmonary Arterial Hypertension by FOXM1-Mediated FAK Phosphorylation.
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
OSBPL2 mutations impair autophagy and lead to hearing loss, potentially remedied by rapamycin.
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Past Exposure to Cigarette Smoke Aggravates Cognitive Impairment in a Rat Model of Vascular Dementia via Neuroinflammation.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus.
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival.
A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue.
Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.
Obesity induced Ext1 reduction mediates the occurrence of NAFLD.
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
Dependence of glucose transport on autophagy and GAPDH activity.
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis.
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.
Rubicon promotes the M2 polarization of Kupffer cells via LC3-associated phagocytosis-mediated clearance to improve liver transplantation.
Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels.
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells.
The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.
Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway.
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma.
Delivery of siRNA Using Functionalized Gold Nanorods Enhances Anti-Osteosarcoma Efficacy.
Protectin DX Attenuates Lumbar Radicular Pain of Non-compressive Disc Herniation by Autophagy Flux Stimulation via Adenosine Monophosphate-Activated Protein Kinase Signaling.
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer.
Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway.
Pathogenic variants of ATG4D in infertile men with non-obstructive azoospermia identified using whole-exome sequencing.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex.
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Radiosensitizing effects of curcumin alone or combined with GLUT1 siRNA on laryngeal carcinoma cells through AMPK pathway-induced autophagy.
U0126 pretreatment inhibits cisplatin-induced apoptosis and autophagy in HEI-OC1 cells and cochlear hair cells.
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension.
Autophagy and post-ischemic conditioning in retinal ischemia.
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis.
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities.
T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).
The Atrophic Effect of 1,25(OH)(2) Vitamin D(3) (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress.
GSK-3β inhibitor TDZD-8 prevents reduction of aquaporin-1 expression via activating autophagy under renal ischemia reperfusion injury.
Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.
Pretreatment of cardiac progenitor cells with bradykinin attenuates H(2)O(2)-induced cell apoptosis and improves cardiac function in rats by regulating autophagy.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Pentraxin 3 Promotes Glioblastoma Progression by Negative Regulating Cells Autophagy.
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
4-Acetylantrocamol LT3, a New Ubiquinone from Antrodia cinnamomea, Inhibits Hepatocellular Carcinoma HepG2 Cell Growth by Targeting YAP/TAZ, mTOR, and WNT/β-Catenin Signaling.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
LncRNA TUG1 regulates autophagy-mediated endothelial-mesenchymal transition of liver sinusoidal endothelial cells by sponging miR-142-3p.
Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells.
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Isovitexin modulates autophagy in Alzheimer's disease via miR-107 signalling.
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.
Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity.
Autophagy associated with the efficacy of valproic acid in PTZ-induced epileptic rats.
The regulatory activity of autophagy in conjunctival fibroblasts and its possible role in vernal keratoconjunctivitis.
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Treadmill Exercise Attenuates Aβ-Induced Mitochondrial Dysfunction and Enhances Mitophagy Activity in APP/PS1 Transgenic Mice.
Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway.
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats.
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Nanoenabled Disruption of Multiple Barriers in Antigen Cross-Presentation of Dendritic Cells via Calcium Interference for Enhanced Chemo-Immunotherapy.
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma.
FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Essential contribution of macrophage Tie2 signal mediated autophagy in laser-induced choroidal neovascularization.
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway.
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy.
Augmenter of Liver Regeneration Protects against Ethanol-Induced Acute Liver Injury by Promoting Autophagy.
Acid Sphingomyelinase Inhibition Attenuates Cell Death in Mechanically Ventilated Newborn Rat Lung.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Autophagy promotes hepatic differentiation of hepatic progenitor cells by regulating the Wnt/β-catenin signaling pathway.
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats.
Autophagy is involved in the differentiation of epicardial progenitor cells into vascular smooth muscle cells in mice.
Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damage.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Nix/BNIP3L-dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke.
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.
Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem.
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)(2)D(3) on the osteoclastogenesis.
Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice.
Di-2-pyridylhydrazone Dithiocarbamate Butyric Acid Ester Exerted Its Proliferative Inhibition against Gastric Cell via ROS-Mediated Apoptosis and Autophagy.
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy.
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis.
NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway.
Mitophagy in three cases of immune-mediated necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: ultrastructural and immunohistochemical studies.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β(1) in human lung fibroblasts.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells.
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice.
Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment.
Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy.
Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
miR-361-5p modulates metabolism and autophagy via the Sp1-mediated regulation of PKM2 in prostate cancer.
Role of autophagy in cadmium-induced testicular injury.
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7.
Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy.
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Autophagy and apoptosis induced by Chinese giant salamander (Andrias davidianus) iridovirus (CGSIV).
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Dimethyl α-ketoglutarate reduces CCl(4)-induced liver fibrosis through inhibition of autophagy in hepatic stellate cells.
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.
Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways.
Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.
Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation.
Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling.
Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response.
Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways.
Inhibition of autophagy promotes caspase-mediated apoptosis by tunicamycin in HepG2 cells.
Modulating autophagy improves cardiac function in a rat model of early-stage dilated cardiomyopathy.
Lin X, Zhang J, Wu Z, Shi Y, Chen M, Li M, Hu H, Tian K, Lv X, Li C, Liu Y, Gao X, Yang Q, Chen K, Zhu A
Frontiers in pharmacology 2024;15:1393717
Frontiers in pharmacology 2024;15:1393717
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Du J, Liu W, Song Y, Zhang Y, Dong C, Xiong S, Huang Z, Wang T, Ding J, He Q, Yu Z, Ma X
Burns & trauma 2024;12:tkad057
Burns & trauma 2024;12:tkad057
Autophagy plays a pro-apoptotic role in arsenic trioxide-induced cell death of liver cancer.
Deng ZT, Liang SF, Huang GK, Wang YQ, Tu XY, Zhang YN, Li S, Liu T, Cheng BB
Journal of integrative medicine 2024 May;22(3):295-302
Journal of integrative medicine 2024 May;22(3):295-302
Selenomethionine preconditioned mesenchymal stem cells derived extracellular vesicles exert enhanced therapeutic efficacy in intervertebral disc degeneration.
Ma S, Xue R, Zhu H, Han Y, Ji X, Zhang C, Wei N, Xu J, Li F
International immunopharmacology 2024 May 10;132:112028
International immunopharmacology 2024 May 10;132:112028
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy.
Villares M, Lourenço N, Ktorza I, Berthelet J, Panagiotou A, Richard A, Amo A, Koziy Y, Medjkane S, Valente S, Fioravanti R, Pioche-Durieu C, Lignière L, Chevreux G, Mai A, Weitzman JB
Nature communications 2024 Mar 12;15(1):2235
Nature communications 2024 Mar 12;15(1):2235
An ATPase-Mimicking MXene nanozyme pharmacologically breaks the ironclad defense system for ferroptosis cancer therapy.
Wang H, Liu X, Yan X, Du Y, Pu F, Ren J, Qu X
Biomaterials 2024 Jun;307:122523
Biomaterials 2024 Jun;307:122523
Stanniocalcin 2 Regulates Autophagy and Ferroptosis in Mammary Epithelial Cells of Dairy Cows Through the Mechanistic Target of Rapamycin Complex 1 Pathway.
Li R, Geng H, Tan X, Wang J, Deng L
The Journal of nutrition 2024 Jun;154(6):1790-1802
The Journal of nutrition 2024 Jun;154(6):1790-1802
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
Zhao W, Zhao B, Meng X, Li B, Wang Y, Yu F, Fu C, Yu X, Li X, Dai C, Wang J, Gao H, Cheng M
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
The targeting of DAPK1 with miR-190a-3p promotes autophagy in trophoblast cells.
Luo QQ, Tian Y, Qu GJ, Huang K, Hu PP, Xue Y, Hu BF, Luo SS
Molecular reproduction and development 2024 Jan;91(1):e23724
Molecular reproduction and development 2024 Jan;91(1):e23724
Targeting PKD2 aggravates ferritinophagy-mediated ferroptosis via promoting autophagosome-lysosome fusion and enhances efficacy of carboplatin in lung adenocarcinoma.
Liu Y, Pang Z, Wang Y, Liu J, Wang G, Du J
Chemico-biological interactions 2024 Jan 5;387:110794
Chemico-biological interactions 2024 Jan 5;387:110794
Response of lipid metabolism, energy supply, and cell fate in yellowstripe goby (Mugilogobius chulae) exposed to environmentally relevant concentrations atorvastatin.
Zhao Y, Duan C, Zhang H, Gong W, Wang Y, Ren J, Nie X, Li J
Environmental pollution (Barking, Essex : 1987) 2024 Jan 15;341:122991
Environmental pollution (Barking, Essex : 1987) 2024 Jan 15;341:122991
The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy.
Xu H, Fu J, Tu Q, Shuai Q, Chen Y, Wu F, Cao Z
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
Journal of physiology and biochemistry 2024 Feb;80(1):27-39
AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.
Zhu L, Wang J, Wu Z, Chen S, He Y, Jiang Y, Luo G, Wu Z, Li Y, Xie J, Zou S, Zhou C
Cell proliferation 2024 Feb;57(2):e13546
Cell proliferation 2024 Feb;57(2):e13546
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
L-Alanine promotes anti-infectious properties of Bacillus subtilis S-2 spores via the germination receptor gerAA.
Lu S, Liao X, Lu W, Zhang L, Na K, Li X, Guo X
Probiotics and antimicrobial proteins 2024 Aug;16(4):1399-1410
Probiotics and antimicrobial proteins 2024 Aug;16(4):1399-1410
Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway.
Luo L, Lin J, Chen S, Ni J, Peng H, Shen F, Huang Z
Journal of ethnopharmacology 2024 Aug 10;330:118196
Journal of ethnopharmacology 2024 Aug 10;330:118196
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Chen H, Zhang H, Li AM, Liu YT, Liu Y, Zhang W, Yang C, Song N, Zhan M, Yang S
Redox biology 2024 Apr;70:103062
Redox biology 2024 Apr;70:103062
Toosendanin induces hepatotoxicity by restraining autophagy and lysosomal function through inhibiting STAT3/CTSC axis.
Luo L, Ni J, Zhang J, Lin J, Chen S, Shen F, Huang Z
Toxicology letters 2024 Apr;394:102-113
Toxicology letters 2024 Apr;394:102-113
PRRSV degrades MDA5 via dual autophagy receptors P62 and CCT2 to evade antiviral innate immunity.
Sun R, Guo Y, Zhang L, Zhang H, Yin B, Li X, Li C, Yang L, Zhang L, Li Z, Huang J
Virologica Sinica 2024 Apr;39(2):264-276
Virologica Sinica 2024 Apr;39(2):264-276
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
Mitophagy activation by rapamycin enhances mitochondrial function and cognition in 5×FAD mice.
Zheng W, Li K, Zhong M, Wu K, Zhou L, Huang J, Liu L, Chen Z
Behavioural brain research 2024 Apr 12;463:114889
Behavioural brain research 2024 Apr 12;463:114889
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
Tan Z, Dong F, Wu L, Feng Y, Zhang M, Zhang F
Mediators of inflammation 2023;2023:5677865
Mediators of inflammation 2023;2023:5677865
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Sun J, Zhou L, Yang T, Deng B, Bao Y, Gu L, Wang H, Wang L
Oxidative medicine and cellular longevity 2023;2023:1696190
Oxidative medicine and cellular longevity 2023;2023:1696190
Metabolic reprogramming induced by DCA enhances cisplatin sensitivity through increasing mitochondrial oxidative stress in cholangiocarcinoma.
Qin H, Zheng G, Li Q, Shen L
Frontiers in pharmacology 2023;14:1128312
Frontiers in pharmacology 2023;14:1128312
PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling.
Lin JC, Liu TP, Chen YB, Yang PM
American journal of cancer research 2023;13(9):4125-4144
American journal of cancer research 2023;13(9):4125-4144
Excessive Lysosomal Stress Response and Consequently Impaired Autophagy Contribute to Fluoride-Induced Developmental Neurotoxicity.
Xu W, Hu Z, Tang Y, Zhang J, Xu S, Niu Q
Biological trace element research 2023 Sep;201(9):4472-4483
Biological trace element research 2023 Sep;201(9):4472-4483
Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor α deficiency, associated with decreased ERK and Akt activation.
Zhou Y, Li L, Chen X, Zhao Q, Qu N, Zhang B, Jin X, Xia C
European journal of medical research 2023 Sep 9;28(1):332
European journal of medical research 2023 Sep 9;28(1):332
Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells.
Mu N, Wang Y, Li X, Du Z, Wu Y, Su M, Wang Y, Sun X, Su L, Liu X
Cell death & disease 2023 Sep 30;14(9):645
Cell death & disease 2023 Sep 30;14(9):645
Targeted Degradation of Alpha-Synuclein by Autophagosome-Anchoring Chimera Peptides.
Tong Y, Zhu W, Chen J, Zhang W, Xu F, Pang J
Journal of medicinal chemistry 2023 Sep 14;66(17):12614-12628
Journal of medicinal chemistry 2023 Sep 14;66(17):12614-12628
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Wang H, Liang Y, Zhang T, Yu X, Song X, Chen Y, Mao Q, Xia W, Chen B, Xu L, Dong G, Jiang F
Cell death and differentiation 2023 Nov;30(11):2365-2381
Cell death and differentiation 2023 Nov;30(11):2365-2381
Galectin-7 promotes cisplatin efficacy by facilitating apoptosis and G3BP1 degradation in cervical cancer.
Liu C, Zhou L, Chen J, Yang Z, Chen S, Wang X, Liu X, Li Y, Zhang C, Wang Y, Chen Y, Li H, Shen C, Sun H
Biochemical pharmacology 2023 Nov;217:115834
Biochemical pharmacology 2023 Nov;217:115834
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Wang Z, Yang T, Zeng M, Wang Z, Chen Q, Chen J, Christian M, He Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
The master antioxidant defense is activated during EBV latent infection.
Wang L, Howell MEA, Hensley CR, Ning K, Moorman JP, Yao ZQ, Ning S
Journal of virology 2023 Nov 30;97(11):e0095323
Journal of virology 2023 Nov 30;97(11):e0095323
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
O-GlcNAcylation regulates OTX2's proteostasis.
Wulff-Fuentes E, Boakye J, Kroenke K, Berendt RR, Martinez-Morant C, Pereckas M, Hanover JA, Olivier-Van Stichelen S
iScience 2023 Nov 17;26(11):108184
iScience 2023 Nov 17;26(11):108184
Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.
Zhang X, Dong Z, Yang Y, Liu C, Li J, Sun W, Zhu Y, Shen Y, Wang Z, Lü M, Cui H
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no-reflow.
Li JJ, Wang YJ, Wang CM, Li YJ, Yang Q, Cai WY, Chen Y, Zhu XX
Phytotherapy research : PTR 2023 May;37(5):1864-1882
Phytotherapy research : PTR 2023 May;37(5):1864-1882
MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.
Mao Y, Wang M, Xiong Y, Wen X, Zhang M, Ma L, Zhang Y
Reproductive sciences (Thousand Oaks, Calif.) 2023 May;30(5):1506-1520
Reproductive sciences (Thousand Oaks, Calif.) 2023 May;30(5):1506-1520
PDK1 inhibition reduces autophagy and cell senescence through the PI3K/AKT signalling pathway in a cigarette smoke mouse emphysema model.
Zhang P, Jiang Y, Ye X, Zhang C, Tang Y
Experimental and therapeutic medicine 2023 May;25(5):223
Experimental and therapeutic medicine 2023 May;25(5):223
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Liao D, Shangguan D, Wu Y, Chen Y, Liu N, Tang J, Yao D, Shi Y
Psychopharmacology 2023 May;240(5):1179-1190
Psychopharmacology 2023 May;240(5):1179-1190
Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression.
Wang G, Chen L, Qin S, Geng H, Xia C, Zheng Y, Lei X, Zhang J, Wu S, Yao J, Deng L
Molecular nutrition & food research 2023 Mar;67(6):e2200517
Molecular nutrition & food research 2023 Mar;67(6):e2200517
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Xia C, Wang G, Chen L, Geng H, Yao J, Bai Z, Deng L
Cell proliferation 2023 Mar;56(3):e13360
Cell proliferation 2023 Mar;56(3):e13360
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Xu W, Ding J, Li B, Sun T, You X, He Q, Sheng W
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
Optic nerve injury models under varying forces.
Sun W, Chao G, Shang M, Wu Q, Xia Y, Wei Q, Zhou J, Liao L
International ophthalmology 2023 Mar;43(3):757-769
International ophthalmology 2023 Mar;43(3):757-769
MiR-141-3p promotes hypoxia-induced autophagy in human placental trophoblast cells.
Luo Q, Tian Y, Qu G, Huang K, Hu P, Li L, Luo S
Reproductive biology 2023 Mar;23(1):100712
Reproductive biology 2023 Mar;23(1):100712
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Hu Z, Xu W, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
Qin C, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cell death & disease 2023 Mar 11;14(3):191
Cell death & disease 2023 Mar 11;14(3):191
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, Wang X, Xiao F
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells.
Li ZB, Jiang L, Ni JD, Xu YH, Liu F, Liu WM, Wang SG, Liu ZQ, Wang CY
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205
Acta pharmacologica Sinica 2023 Jun;44(6):1191-1205
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2023 Jun;39(3):729-749
Cell biology and toxicology 2023 Jun;39(3):729-749
Autophagy gene Atg7 regulates the development of radiation-induced skin injury and fibrosis of skin.
Chen X, Qin W, Wang L, Jin Y, Tu J, Yuan X
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023 Jun;29(6):e13337
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2023 Jun;29(6):e13337
Mitochondrial damage-induced abnormal glucose metabolism with ageing in the hippocampus of APP/PS1 mice.
Li S, Wang Y, Zhang X, Xiong X, Zhou F, Li X, Fan J, Liang X, Li G, Peng Y, Li Y
Metabolomics : Official journal of the Metabolomic Society 2023 Jun 8;19(6):56
Metabolomics : Official journal of the Metabolomic Society 2023 Jun 8;19(6):56
Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
Tong Y, Zhu W, Chen J, Wen T, Xu F, Pang J
Journal of medicinal chemistry 2023 Jun 22;66(12):7926-7942
Journal of medicinal chemistry 2023 Jun 22;66(12):7926-7942
Berberine attenuates liver fibrosis by autophagy inhibition triggering apoptosis via the miR-30a-5p/ATG5 axis.
Tan Y, Li C, Zhou J, Deng F, Liu Y
Experimental cell research 2023 Jun 15;427(2):113600
Experimental cell research 2023 Jun 15;427(2):113600
LncRNA MEG3 regulates ASK1/JNK axis-mediated apoptosis and autophagy via sponging miR-23a in granulosa cells of yak tertiary follicles.
Han X, Pan Y, Fan J, Wang M, Wang L, Wang J, Afedo SY, Zhao L, Wang Y, Zhao T, Zhang T, Zhang R, Cui Y, Yu S
Cellular signalling 2023 Jul;107:110680
Cellular signalling 2023 Jul;107:110680
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241
Functional & integrative genomics 2023 Jul 14;23(3):241
Hydrogen sulfide inhibits human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG4B.
Liu H, Sun J, Cheng X, Duan L, Guo S, Zhang Z, Wan J, Wang C, Zhi X, Yuan L, Wang H
Journal of medical virology 2023 Jan;95(1):e28176
Journal of medical virology 2023 Jan;95(1):e28176
Induction of autophagy via the PI3K/Akt/mTOR signaling pathway by Pueraria flavonoids improves non-alcoholic fatty liver disease in obese mice.
Sun C, Zhang J, Hou J, Hui M, Qi H, Lei T, Zhang X, Zhao L, Du H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114005
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114005
Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.
Zhuge R, Li Z, He C, Ma W, Yan J, Xue Q, Wang R, Liu Y, Lu R, Du H, Yin F, Guo L
Environmental toxicology 2023 Feb;38(2):289-299
Environmental toxicology 2023 Feb;38(2):289-299
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
Qin S, Wang G, Chen L, Geng H, Zheng Y, Xia C, Wu S, Yao J, Deng L
PLoS genetics 2023 Feb;19(2):e1010629
PLoS genetics 2023 Feb;19(2):e1010629
FUNDC1/PFKP-mediated mitophagy induced by KD025 ameliorates cartilage degeneration in osteoarthritis.
Fang G, Wen X, Jiang Z, Du X, Liu R, Zhang C, Huang G, Liao W, Zhang Z
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Dec 6;31(12):3594-3612
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Dec 6;31(12):3594-3612
Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity.
Guo X, Xu L, Kong Y, Li M, Zhai Q, Liang B, Zhao X, Long L, Huang M, Wang W, Li C
iScience 2023 Dec 15;26(12):108485
iScience 2023 Dec 15;26(12):108485
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma.
Luo M, Su Z, Gao H, Tan J, Liao R, Yang J, Lin L
Journal of translational medicine 2023 Dec 12;21(1):907
Journal of translational medicine 2023 Dec 12;21(1):907
Blockade of CXCR4 promotes macrophage autophagy through the PI3K/AKT/mTOR pathway to alleviate coronary heart disease.
Li F, Peng J, Lu Y, Zhou M, Liang J, Le C, Ding J, Wang J, Dai J, Wan C, Wang J, Luo P, Xia B
International journal of cardiology 2023 Dec 1;392:131303
International journal of cardiology 2023 Dec 1;392:131303
Mitophagy-dependent cardioprotection of resistance training on heart failure.
Guo C, Wu RY, Dou JH, Song SF, Sun XL, Hu YW, Guo FS, Wei J, Lin L, Wei J
Journal of applied physiology (Bethesda, Md. : 1985) 2023 Dec 1;135(6):1390-1401
Journal of applied physiology (Bethesda, Md. : 1985) 2023 Dec 1;135(6):1390-1401
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization.
Zheng Z, Han L, Li Y, Chen Z, Yang W, Liu C, Tao M, Jiang Y, Ke X, Liu Y, Guo X
Biochimica et biophysica acta. Molecular cell research 2023 Aug;1870(6):119487
Biochimica et biophysica acta. Molecular cell research 2023 Aug;1870(6):119487
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Xue X, Dai T, Chen J, Xu Y, Yang Z, Huang J, Xu W, Li S, Meng Q
Journal of orthopaedic surgery and research 2023 Aug 24;18(1):620
Journal of orthopaedic surgery and research 2023 Aug 24;18(1):620
Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2.
Zheng Y, Zhan Y, Zhang Y, Zhang Y, Liu Y, Xie Y, Sun Y, Qian J, Ding Y, Ding Y, Fang Y
Cell death & disease 2023 Aug 1;14(8):488
Cell death & disease 2023 Aug 1;14(8):488
Melatonin inhibits atherosclerosis progression via galectin-3 downregulation to enhance autophagy and inhibit inflammation.
Wang Z, Gao Z, Zheng Y, Kou J, Song D, Yu X, Dong B, Chen T, Yang Y, Gao X, Wang Q, Ye T, Yang W, Zhang X, Li H, Yang L
Journal of pineal research 2023 Apr;74(3):e12855
Journal of pineal research 2023 Apr;74(3):e12855
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Tan H, Cao L
Immunity, inflammation and disease 2023 Apr;11(4):e830
Immunity, inflammation and disease 2023 Apr;11(4):e830
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
Plasminogen decreases Aβ42 and Tau deposition, and shows multi-beneficial effects on Alzheimer's disease in mice and humans.
Guo C, Wang T, Zhang D, Ge X, Li J
Biochemical and biophysical research communications 2023 Apr 30;654:102-111
Biochemical and biophysical research communications 2023 Apr 30;654:102-111
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Wang G, Qin S, Chen L, Geng H, Zheng Y, Xia C, Yao J, Deng L
Cell death & disease 2023 Apr 25;14(4):292
Cell death & disease 2023 Apr 25;14(4):292
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Xiong W, Huang XL, Li CY, Wang XL, Lan HW, Wang TT, Chen ZL, Yang QP, Hu AL, Xia YF, Zhu FR, Zhou ZZ
Folia histochemica et cytobiologica 2022;60(4):323-334
Folia histochemica et cytobiologica 2022;60(4):323-334
Ethyl Extract of Blaps rynchopetera Fairmaire Ameliorates Experimental Aerobic Vaginitis by Inhibiting Autophagy Activation.
Liu J, Yuan S, Zhao Z, Lu H
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7938733
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7938733
The Role of Autophagy in Lamellar Body Formation and Surfactant Production in Type 2 Alveolar Epithelial Cells.
Li X, Wang L, Hao J, Zhu Q, Guo M, Wu C, Li S, Guo Q, Ren Q, Bai N, Yi F, Jiang B, Zhang W, Feng Y, Xu H, Jiang H, Zhai X, Zhang G, Ji HL, Yang X, Zhang D, Fu J, Chang J, Song X, Cao L
International journal of biological sciences 2022;18(3):1107-1119
International journal of biological sciences 2022;18(3):1107-1119
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.
Huang TT, Chen CM, Chen LG, Lan YW, Huang TH, Choo KB, Chong KY
Frontiers in pharmacology 2022;13:997100
Frontiers in pharmacology 2022;13:997100
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Wang T, Lu Z, Qu XH, Xiong ZY, Wu YT, Luo Y, Zhang ZY, Han XJ, Xie CF
Frontiers in pharmacology 2022;13:951521
Frontiers in pharmacology 2022;13:951521
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
Hu H, Li P, Qiu J, Zhao M, Kuang M, Zhang Z, Wang D
Frontiers in pharmacology 2022;13:932807
Frontiers in pharmacology 2022;13:932807
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.
Zhang KK, Chen LJ, Li JH, Liu JL, Wang LB, Xu LL, Yang JZ, Li XW, Xie XL, Wang Q
Frontiers in microbiology 2022;13:755189
Frontiers in microbiology 2022;13:755189
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Zhu H, Liu H, Chen X, Xu X, Zhang S, Xie D
Frontiers in cell and developmental biology 2022;10:971736
Frontiers in cell and developmental biology 2022;10:971736
Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway.
Chen R, Yang H, Song Y, Yu H, Zhang M, Rao W, Wang Y, Xiao X, Chen Q, He Q
Molecular genetics and genomics : MGG 2022 Sep;297(5):1277-1287
Molecular genetics and genomics : MGG 2022 Sep;297(5):1277-1287
Moxidectin induces autophagy arrest in colorectal cancer.
Mao Y, Xie H, Shu D, Cheng L, Lan J, Pan K
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
Activation of Autophagy Induces Monocrotaline-Induced Pulmonary Arterial Hypertension by FOXM1-Mediated FAK Phosphorylation.
Zhai C, Zhang N, Wang J, Cao M, Luan J, Liu H, Zhang Q, Zhu Y, Xue Y, Li S
Lung 2022 Oct;200(5):619-631
Lung 2022 Oct;200(5):619-631
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Zhao Y, Lin J, Li J, Bwalya C, Xu Y, Niu Y, Zhang Y, Wu J, Xu Y, Chen J, Ye S, Lin L
International journal of molecular sciences 2022 Oct 18;23(20)
International journal of molecular sciences 2022 Oct 18;23(20)
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
Wen F, Zhan Q, Zou T, Tan ZG, Xiang J
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927
Epileptic disorders : international epilepsy journal with videotape 2022 Oct 1;24(5):917-927
OSBPL2 mutations impair autophagy and lead to hearing loss, potentially remedied by rapamycin.
Koh YI, Oh KS, Kim JA, Noh B, Choi HJ, Joo SY, Rim JH, Kim HY, Kim DY, Yu S, Kim DH, Lee SG, Jung J, Choi JY, Gee HY
Autophagy 2022 Nov;18(11):2593-2614
Autophagy 2022 Nov;18(11):2593-2614
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Qin S, Geng H, Wang G, Chen L, Xia C, Yao J, Bai Z, Deng L
Nutrients 2022 Nov 24;14(23)
Nutrients 2022 Nov 24;14(23)
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Yang X, Wang M, Zhou Q, Bai Y, Liu J, Yang J, Li L, Li G, Luo L
Molecular neurobiology 2022 May;59(5):2776-2798
Molecular neurobiology 2022 May;59(5):2776-2798
Past Exposure to Cigarette Smoke Aggravates Cognitive Impairment in a Rat Model of Vascular Dementia via Neuroinflammation.
Meng N, Dong Y, Huo T, Song M, Jiang X, Xiao Y, Lv P
Cellular and molecular neurobiology 2022 May;42(4):1021-1034
Cellular and molecular neurobiology 2022 May;42(4):1021-1034
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus.
Liu J, Wang L, Ge L, Sun W, Song Z, Lu X, Jin C, Wu S, Yang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Mar;161:112831
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Mar;161:112831
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Liu H, He S, Wang J, Li C, Liao Y, Zou Q, Chen R
Neurochemical research 2022 Jun;47(6):1574-1587
Neurochemical research 2022 Jun;47(6):1574-1587
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2022 Jun;18(6):1416-1432
Autophagy 2022 Jun;18(6):1416-1432
Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival.
Song Y, Ge X, Chen Y, Hussain T, Liang Z, Dong Y, Wang Y, Tang C, Zhou X
Autophagy 2022 Jun;18(6):1401-1415
Autophagy 2022 Jun;18(6):1401-1415
A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue.
Zhang S, Gong F, Liu J, Liu T, Yang J, Hu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113004
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113004
Exercise training improves cardiac function and regulates myocardial mitophagy differently in ischaemic and pressure-overload heart failure mice.
Guo C, Chen MJ, Zhao JR, Wu RY, Zhang Y, Li QQ, Zhao H, Dou JH, Song SF, Wei J
Experimental physiology 2022 Jun;107(6):562-574
Experimental physiology 2022 Jun;107(6):562-574
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.
Mei J, Sheng X, Yan Y, Cai X, Zhang C, Tian J, Zhang M, Zhou J, Shan H, Huang C
BMC molecular and cell biology 2022 Jun 27;23(1):24
BMC molecular and cell biology 2022 Jun 27;23(1):24
Obesity induced Ext1 reduction mediates the occurrence of NAFLD.
Wang M, Li B, Qin F, Ye J, Jin L
Biochemical and biophysical research communications 2022 Jan 22;589:123-130
Biochemical and biophysical research communications 2022 Jan 22;589:123-130
Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.
Zhang Y, Han X, Tang Y, Zhang J, Hu Z, Xu W, Yao P, Niu Q
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
Ecotoxicology and environmental safety 2022 Jan 15;230:113108
Mitochondria-Dependent Oxidative Stress Mediates ZnO Nanoparticle (ZnO NP)-Induced Mitophagy and Lipotoxicity in Freshwater Teleost Fish.
Chen GH, Song CC, Zhao T, Hogstrand C, Wei XL, Lv WH, Song YF, Luo Z
Environmental science & technology 2022 Feb 15;56(4):2407-2420
Environmental science & technology 2022 Feb 15;56(4):2407-2420
Dependence of glucose transport on autophagy and GAPDH activity.
Craven RJ, Frazier HN, Thibault O
Brain research 2022 Feb 1;1776:147747
Brain research 2022 Feb 1;1776:147747
circRNA-MSR regulates the expression of FBXO21 to inhibit chondrocyte autophagy by targeting miR-761 in osteoarthritis.
Jia Z, Liu J, Wang J
The Kaohsiung journal of medical sciences 2022 Dec;38(12):1168-1177
The Kaohsiung journal of medical sciences 2022 Dec;38(12):1168-1177
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.
Yan G, Li X, Zheng Z, Gao W, Chen C, Wang X, Cheng Z, Yu J, Zou G, Farooq MZ, Zhu X, Zhu W, Zhong Q, Yan X
Autophagy 2022 Dec;18(12):2799-2816
Autophagy 2022 Dec;18(12):2799-2816
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Liu L, Li X, Bu W, Jin N, Meng Y, Wang Y, Wang D, Xu X, Zhou D, Sun H
Materials today. Bio 2022 Dec;16:100344
Materials today. Bio 2022 Dec;16:100344
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Hao J, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Wei C, Li H
Cellular signalling 2022 Dec;100:110465
Cellular signalling 2022 Dec;100:110465
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
Luo L, Liang Y, Fu Y, Liang Z, Zheng J, Lan J, Shen F, Huang Z
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells.
Zhang Y, Yao E, Liu Y, Zhang Y, Ding M, Liu J, Chen X, Fan S
Cells 2022 Dec 13;11(24)
Cells 2022 Dec 13;11(24)
Rubicon promotes the M2 polarization of Kupffer cells via LC3-associated phagocytosis-mediated clearance to improve liver transplantation.
Chen Y, He Y, Wu X, Xu X, Gong J, Chen Y, Gong J
Cellular immunology 2022 Aug;378:104556
Cellular immunology 2022 Aug;378:104556
Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels.
Jian Y, Yuan S, Yang J, Lei Y, Li X, Liu W
International journal of molecular sciences 2022 Aug 31;23(17)
International journal of molecular sciences 2022 Aug 31;23(17)
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Liu K, Qiu D, Liang X, Huang Y, Wang Y, Jia X, Li K, Zhao J, Du C, Qiu X, Cui J, Xiao Z, Qin Y, Zhang Q
Autophagy 2022 Apr;18(4):860-876
Autophagy 2022 Apr;18(4):860-876
SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells.
Fang X, Xia W, Li S, Qi Y, Liu M, Yu Y, Li H, Li M, Tao C, Wang Z, Li J
International journal of molecular sciences 2022 Apr 30;23(9)
International journal of molecular sciences 2022 Apr 30;23(9)
The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy.
Zhang G, Han J, Wang L, Yang X, Yan Z, Qu M, Zhou H, Bilal H, Wang F, Ge H, Yang X
iScience 2022 Apr 15;25(4):104085
iScience 2022 Apr 15;25(4):104085
Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway.
Tang X, Sun Y, Xu C, Guo X, Sun J, Pan C, Sun J
Frontiers in cell and developmental biology 2021;9:751012
Frontiers in cell and developmental biology 2021;9:751012
Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma.
Zhang M, Bai Y, Xu C, Qi Y, Meng J, Zhang W, Su H, Yan W
Frontiers in cell and developmental biology 2021;9:650846
Frontiers in cell and developmental biology 2021;9:650846
Receptor-Interacting Protein Kinase 3 Inhibition Prevents Cadmium-Mediated Macrophage Polarization and Subsequent Atherosclerosis via Maintaining Mitochondrial Homeostasis.
Zhang J, Feng W, Li M, Chen P, Ning X, Ou C, Chen M
Frontiers in cardiovascular medicine 2021;8:737652
Frontiers in cardiovascular medicine 2021;8:737652
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718
Journal of oncology 2021;2021:8281718
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Jiang H, Liu J, Zhang K, Zeng Q
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5451758
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5451758
Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma.
Liu M, Shan M, Zhang Y, Guo Z
Journal of inflammation research 2021;14:3891-3904
Journal of inflammation research 2021;14:3891-3904
Delivery of siRNA Using Functionalized Gold Nanorods Enhances Anti-Osteosarcoma Efficacy.
Zhang M, Lin J, Jin J, Yu W, Qi Y, Tao H
Frontiers in pharmacology 2021;12:799588
Frontiers in pharmacology 2021;12:799588
Protectin DX Attenuates Lumbar Radicular Pain of Non-compressive Disc Herniation by Autophagy Flux Stimulation via Adenosine Monophosphate-Activated Protein Kinase Signaling.
Zhao QX, Wang YH, Wang SC, Xue S, Cao ZX, Sun T
Frontiers in physiology 2021;12:784653
Frontiers in physiology 2021;12:784653
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Liu S, Guo W, Jia Y, Ye B, Liu S, Fu S, Liu J, Hu G
Frontiers in immunology 2021;12:782989
Frontiers in immunology 2021;12:782989
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ji W, Wan T, Zhang F, Zhu X, Guo S, Mei X
Frontiers in pharmacology 2021;12:641058
Frontiers in pharmacology 2021;12:641058
Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer.
Chang YC, Chang PM, Li CH, Chan MH, Lee YJ, Chen MH, Hsiao M
Frontiers in oncology 2021;11:811635
Frontiers in oncology 2021;11:811635
Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway.
Sun Y, Liu W, Zhao Q, Zhang R, Wang J, Pan P, Shang H, Liu C, Wang C
Frontiers in oncology 2021;11:653596
Frontiers in oncology 2021;11:653596
Pathogenic variants of ATG4D in infertile men with non-obstructive azoospermia identified using whole-exome sequencing.
Sha Y, Liu W, Wei X, Zhu X, Tang B, Zhang X, Yang X, Wang Y, Wang X
Clinical genetics 2021 Sep;100(3):280-291
Clinical genetics 2021 Sep;100(3):280-291
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X, Wu C
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Ecotoxicology and environmental safety 2021 Oct 1;222:112529
Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex.
Wang S, Wuniqiemu T, Tang W, Teng F, Bian Q, Yi L, Qin J, Zhu X, Wei Y, Dong J
International immunopharmacology 2021 May;94:107460
International immunopharmacology 2021 May;94:107460
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Sun F, Wang Z, Wang X
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2021 May-Jun;26(3):924-931
Radiosensitizing effects of curcumin alone or combined with GLUT1 siRNA on laryngeal carcinoma cells through AMPK pathway-induced autophagy.
Dai LB, Zhong JT, Shen LF, Zhou SH, Lu ZJ, Bao YY, Fan J
Journal of cellular and molecular medicine 2021 May 6;
Journal of cellular and molecular medicine 2021 May 6;
U0126 pretreatment inhibits cisplatin-induced apoptosis and autophagy in HEI-OC1 cells and cochlear hair cells.
Wang D, Shi S, Ren T, Zhang Y, Guo P, Wang J, Wang W
Toxicology and applied pharmacology 2021 Mar 15;415:115447
Toxicology and applied pharmacology 2021 Mar 15;415:115447
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension.
Feng W, Wang J, Yan X, Zhang Q, Chai L, Wang Q, Shi W, Chen Y, Liu J, Qu Z, Li S, Xie X, Li M
Cell proliferation 2021 Jun;54(6):e13048
Cell proliferation 2021 Jun;54(6):e13048
Autophagy and post-ischemic conditioning in retinal ischemia.
Mathew B, Chennakesavalu M, Sharma M, Torres LA, Stelman CR, Tran S, Patel R, Burg N, Salkovski M, Kadzielawa K, Seiler F, Aldrich LN, Roth S
Autophagy 2021 Jun;17(6):1479-1499
Autophagy 2021 Jun;17(6):1479-1499
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Ruan C, Wang C, Gong X, Zhang Y, Deng W, Zhou J, Huang D, Wang Z, Zhang Q, Guo A, Lu J, Gao J, Peng D, Xue Y
Autophagy 2021 Jun;17(6):1426-1447
Autophagy 2021 Jun;17(6):1426-1447
Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Isogawa K, Asano M, Hayazaki M, Koga K, Watanabe M, Suzuki K, Kobayashi T, Kawaguchi K, Ishizuka A, Kato S, Ito H, Hamamoto A, Koyama H, Furuta K, Takemori H
Journal of cellular biochemistry 2021 Jun;122(6):667-678
Journal of cellular biochemistry 2021 Jun;122(6):667-678
Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis.
Sharma P, Alizadeh J, Juarez M, Samali A, Halayko AJ, Kenyon NJ, Ghavami S, Zeki AA
Cells 2021 Jun 30;10(7)
Cells 2021 Jun 30;10(7)
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1.
Zhang X, Lv S, Zhang W, Jia Q, Wang L, Ding Y, Yuan P, Zhu Y, Liu L, Li Y, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111582
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy.
Liu J, He J, Ge L, Xiao H, Huang Y, Zeng L, Jiang Z, Lu M, Hu Z
Stem cell research & therapy 2021 Jul 22;12(1):413
Stem cell research & therapy 2021 Jul 22;12(1):413
Protective effect of naringenin against cadmium-induced testicular toxicity in male SD rats.
Wang J, Zhu H, Lin S, Wang K, Wang H, Liu Z
Journal of inorganic biochemistry 2021 Jan;214:111310
Journal of inorganic biochemistry 2021 Jan;214:111310
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
Feng S, Qiu G, Yang L, Feng L, Fan X, Ren F, Huang K, Chen Y
Bioscience reports 2021 Jan 29;41(1)
Bioscience reports 2021 Jan 29;41(1)
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3.
Zhou K, Xu Y, Wang Q, Dong L
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
Acta biochimica et biophysica Sinica 2021 Feb 4;53(2):140-148
QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway.
Lv S, Yuan P, Lu C, Dong J, Li M, Qu F, Zhu Y, Zhang J
Aging 2021 Feb 11;13(4):5525-5538
Aging 2021 Feb 11;13(4):5525-5538
Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities.
Zhang X, Qin Y, Wan X, Liu H, Lv C, Ruan W, He L, Lu L, Guo X
Journal of translational medicine 2021 Feb 10;19(1):62
Journal of translational medicine 2021 Feb 10;19(1):62
T-2 Toxin Induces Ferroptosis by Increasing Lipid Reactive Oxygen Species (ROS) and Downregulating Solute Carrier Family 7 Member 11 (SLC7A11).
Wang G, Qin S, Zheng Y, Xia C, Zhang P, Zhang L, Yao J, Yi Y, Deng L
Journal of agricultural and food chemistry 2021 Dec 29;69(51):15716-15727
Journal of agricultural and food chemistry 2021 Dec 29;69(51):15716-15727
The Atrophic Effect of 1,25(OH)(2) Vitamin D(3) (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress.
Raiteri T, Zaggia I, Reano S, Scircoli A, Salvadori L, Prodam F, Filigheddu N
Antioxidants (Basel, Switzerland) 2021 Dec 12;10(12)
Antioxidants (Basel, Switzerland) 2021 Dec 12;10(12)
GSK-3β inhibitor TDZD-8 prevents reduction of aquaporin-1 expression via activating autophagy under renal ischemia reperfusion injury.
Liu Q, Kong Y, Guo X, Liang B, Xie H, Hu S, Han M, Zhao X, Feng P, Lyu Q, Dong W, Liang X, Wang W, Li C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Aug;35(8):e21809
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Aug;35(8):e21809
Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.
Xu L, Zhu L, Liu P, Wu Z, Zou Z
Experimental and therapeutic medicine 2021 Aug;22(2):869
Experimental and therapeutic medicine 2021 Aug;22(2):869
Pretreatment of cardiac progenitor cells with bradykinin attenuates H(2)O(2)-induced cell apoptosis and improves cardiac function in rats by regulating autophagy.
Wu C, Zhou XX, Li JZ, Qiang HF, Wang Y, Li G
Stem cell research & therapy 2021 Aug 5;12(1):437
Stem cell research & therapy 2021 Aug 5;12(1):437
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process.
Tan YZ, Xu XY, Dai JM, Yin Y, He XT, Zhang YL, Zhu TX, An Y, Tian BM, Chen FM
Stem cell research & therapy 2021 Apr 29;12(1):254
Stem cell research & therapy 2021 Apr 29;12(1):254
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G
Journal of extracellular vesicles 2020;9(1):1716513
Journal of extracellular vesicles 2020;9(1):1716513
Pentraxin 3 Promotes Glioblastoma Progression by Negative Regulating Cells Autophagy.
Wang Z, Wang X, Zhang N, Zhang H, Dai Z, Zhang M, Feng S, Cheng Q
Frontiers in cell and developmental biology 2020;8:795
Frontiers in cell and developmental biology 2020;8:795
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874
The American journal of Chinese medicine 2020;48(8):1859-1874
Geniposide Enhances Macrophage Autophagy through Downregulation of TREM2 in Atherosclerosis.
Xu YL, Liu XY, Cheng SB, He PK, Hong MK, Chen YY, Zhou FH, Jia YH
The American journal of Chinese medicine 2020;48(8):1821-1840
The American journal of Chinese medicine 2020;48(8):1821-1840
4-Acetylantrocamol LT3, a New Ubiquinone from Antrodia cinnamomea, Inhibits Hepatocellular Carcinoma HepG2 Cell Growth by Targeting YAP/TAZ, mTOR, and WNT/β-Catenin Signaling.
Chen YL, Yen IC, Lin KT, Lai FY, Lee SY
The American journal of Chinese medicine 2020;48(5):1243-1261
The American journal of Chinese medicine 2020;48(5):1243-1261
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis.
Hongna Y, Hongzhao T, Quan L, Delin F, Guijun L, Xiaolin L, Fulin G, Zhongren S
Frontiers in neuroscience 2020;14:616864
Frontiers in neuroscience 2020;14:616864
Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke.
Wang MM, Zhang M, Feng YS, Xing Y, Tan ZX, Li WB, Dong F, Zhang F
Frontiers in cellular neuroscience 2020;14:134
Frontiers in cellular neuroscience 2020;14:134
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Xu X, Chen B, Huang Q, Wu Y, Liang T
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
LncRNA TUG1 regulates autophagy-mediated endothelial-mesenchymal transition of liver sinusoidal endothelial cells by sponging miR-142-3p.
Zhang R, Huang XQ, Jiang YY, Li N, Wang J, Chen SY
American journal of translational research 2020;12(3):758-772
American journal of translational research 2020;12(3):758-772
Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells.
Zuo H, Chen C, Ma L, Min QX, Shen YH
American journal of translational research 2020;12(10):6478-6489
American journal of translational research 2020;12(10):6478-6489
Pyruvate dehydrogenase kinase 1 interferes with glucose metabolism reprogramming and mitochondrial quality control to aggravate stress damage in cancer.
Deng X, Wang Q, Cheng M, Chen Y, Yan X, Guo R, Sun L, Li Y, Liu Y
Journal of Cancer 2020;11(4):962-973
Journal of Cancer 2020;11(4):962-973
Isovitexin modulates autophagy in Alzheimer's disease via miR-107 signalling.
Cheng J, Wang G, Zhang N, Li F, Shi L, Li H
Translational neuroscience 2020;11(1):391-401
Translational neuroscience 2020;11(1):391-401
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Zheng Y, Zhu G, Tang Y, Yan J, Han S, Yin J, Peng B, He X, Liu W
Frontiers in microbiology 2020;11:78
Frontiers in microbiology 2020;11:78
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
Xu Q, Fan Y, Loor JJ, Liang Y, Sun X, Jia H, Zhao C, Xu C
Frontiers in pharmacology 2020;11:601716
Frontiers in pharmacology 2020;11:601716
Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy.
Liu W, Zhou J, Niu F, Pu F, Wang Z, Huang M, Zhao X, Yang L, Tao P, Xia P, Feng J
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
Experimental and therapeutic medicine 2020 Sep;20(3):1889-1898
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.
Ye X, Xie G, Liu Z, Tang J, Cui M, Wang C, Guo C, Tang J
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703
Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy.
You M, Miao Z, Tian J, Hu F
European journal of nutrition 2020 Oct;59(7):2875-2892
European journal of nutrition 2020 Oct;59(7):2875-2892
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Lv S, Yuan P, Dong J, Lu C, Li M, Qu F, Zhu Y, Yuan Z, Zhang J
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J
Autophagy 2020 Oct;16(10):1786-1806
Autophagy 2020 Oct;16(10):1786-1806
Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity.
Zhang Y, Ma Y, Xiao Y, Lu C, Xiao F
Ecotoxicology and environmental safety 2020 Oct 15;203:110928
Ecotoxicology and environmental safety 2020 Oct 15;203:110928
Autophagy associated with the efficacy of valproic acid in PTZ-induced epileptic rats.
Wang Y, Wang G, Tao J, Li X, Hu L, Li Q, Lu J, Li Y, Li Z
Brain research 2020 Oct 15;1745:146923
Brain research 2020 Oct 15;1745:146923
The regulatory activity of autophagy in conjunctival fibroblasts and its possible role in vernal keratoconjunctivitis.
Brun P, Tarricone E, Di Stefano A, Mattiuzzo E, Mehrbod P, Ghavami S, Leonardi A
The Journal of allergy and clinical immunology 2020 Nov;146(5):1210-1213.e9
The Journal of allergy and clinical immunology 2020 Nov;146(5):1210-1213.e9
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y
International journal of oncology 2020 May;56(5):1162-1174
International journal of oncology 2020 May;56(5):1162-1174
Treadmill Exercise Attenuates Aβ-Induced Mitochondrial Dysfunction and Enhances Mitophagy Activity in APP/PS1 Transgenic Mice.
Zhao N, Yan QW, Xia J, Zhang XL, Li BX, Yin LY, Xu B
Neurochemical research 2020 May;45(5):1202-1214
Neurochemical research 2020 May;45(5):1202-1214
Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway.
Guo W, Liu J, Li W, Ma H, Gong Q, Kan X, Cao Y, Wang J, Fu S
International journal of molecular sciences 2020 May 8;21(9)
International journal of molecular sciences 2020 May 8;21(9)
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Ma R, Zhang BW, Zhang ZB, Deng QJ
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats.
Tan XH, Zhang KK, Xu JT, Qu D, Chen LJ, Li JH, Wang Q, Wang HJ, Xie XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Mar;137:111179
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Mar;137:111179
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2.
Irungbam K, Churin Y, Matono T, Weglage J, Ocker M, Glebe D, Hardt M, Koeppel A, Roderfeld M, Roeb E
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):454-465
High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells.
Li K, Deng Y, Deng G, Chen P, Wang Y, Wu H, Ji Z, Yao Z, Zhang X, Yu B, Zhang K
Stem cell research & therapy 2020 Mar 20;11(1):131
Stem cell research & therapy 2020 Mar 20;11(1):131
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma.
Huang X, Chen J, Wu W, Yang W, Zhong B, Qing X, Shao Z
Acta biomaterialia 2020 Jun;109:229-243
Acta biomaterialia 2020 Jun;109:229-243
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
Nanoenabled Disruption of Multiple Barriers in Antigen Cross-Presentation of Dendritic Cells via Calcium Interference for Enhanced Chemo-Immunotherapy.
An J, Zhang K, Wang B, Wu S, Wang Y, Zhang H, Zhang Z, Liu J, Shi J
ACS nano 2020 Jun 23;14(6):7639-7650
ACS nano 2020 Jun 23;14(6):7639-7650
10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells.
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F
International immunopharmacology 2020 Jul;84:106501
International immunopharmacology 2020 Jul;84:106501
Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy.
Wang J, Zhu H, Wang K, Yang Z, Liu Z
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Environmental science and pollution research international 2020 Jul;27(20):25278-25286
Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.
Xu D, Liu J, Ma H, Guo W, Wang J, Kan X, Li Y, Gong Q, Cao Y, Cheng J, Fu S
International immunopharmacology 2020 Jan;78:105983
International immunopharmacology 2020 Jan;78:105983
Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells.
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, Ren L
Cell biology international 2020 Jan;44(1):127-136
Cell biology international 2020 Jan;44(1):127-136
ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma.
Zhang Z, Liu R, Shuai Y, Huang Y, Jin R, Wang X, Luo J
British journal of cancer 2020 Jan;122(1):82-93
British journal of cancer 2020 Jan;122(1):82-93
FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction.
Wang Y, Liang HX, Zhang CM, Zou M, Zou BB, Wei W, Hu W
Translational cancer research 2020 Feb;9(2):937-948
Translational cancer research 2020 Feb;9(2):937-948
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
E L, Jiang H
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Pharmaceutical biology 2020 Dec;58(1):1077-1084
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Luo Y, Peng J, Huang C, Cao Y
Ecotoxicology and environmental safety 2020 Aug;199:110714
Ecotoxicology and environmental safety 2020 Aug;199:110714
Essential contribution of macrophage Tie2 signal mediated autophagy in laser-induced choroidal neovascularization.
Zhang B, Yin X, Li J, Ren C, Liu W, Liu G, Lu P
Experimental eye research 2020 Apr;193:107972
Experimental eye research 2020 Apr;193:107972
Exogenous H(2)S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, Peng S, Sun X, Yu M, Chen H, Wang Y, Zhang L, Liu N, Du H, Zhao D, Zhang W
Aging and disease 2020 Apr;11(2):269-285
Aging and disease 2020 Apr;11(2):269-285
DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway.
Wang Z, Li C, Li Y, Guo X, Yan Z, Gao F, Li C
Oxidative medicine and cellular longevity 2019;2019:5414670
Oxidative medicine and cellular longevity 2019;2019:5414670
Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species.
Wang H, Zhao Z, Lei S, Li S, Xiang Z, Wang X, Huang X, Xia G, Huang X
Cancer cell international 2019;19:7
Cancer cell international 2019;19:7
Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway.
Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, Zhou S, Jiang Y, Yang X, Zhang R, Shen L
American journal of translational research 2019;11(4):2042-2055
American journal of translational research 2019;11(4):2042-2055
Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.
Jia J, Gong X, Zhao Y, Yang Z, Ji K, Luan T, Zang B, Li G
Frontiers in immunology 2019;10:1491
Frontiers in immunology 2019;10:1491
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Zhang C, Zhan J, Zhao M, Dai H, Deng Y, Zhou W, Zhao L
Neurotoxicology 2019 Sep;74:74-80
Neurotoxicology 2019 Sep;74:74-80
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, Gao M, Li Y
Aging 2019 Sep 6;11(17):7036-7050
Aging 2019 Sep 6;11(17):7036-7050
PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Hussain Mangi M, Yao J, Dong H, Yang L, Zhou X
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation.
Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, Wang Y, Huang Y, Zhang J, Li Q
International journal of oncology 2019 May;54(5):1601-1612
International journal of oncology 2019 May;54(5):1601-1612
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.
Liu X, Zhao P, Wang X, Wang L, Zhu Y, Song Y, Gao W
Journal of experimental & clinical cancer research : CR 2019 May 3;38(1):184
Journal of experimental & clinical cancer research : CR 2019 May 3;38(1):184
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Hussain T, Zhao D, Shah SZA, Sabir N, Wang J, Liao Y, Song Y, Dong H, Hussain Mangi M, Ni J, Yang L, Zhou X
Cells 2019 May 26;8(5)
Cells 2019 May 26;8(5)
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy.
Wang Y, Meng C, Zhang J, Wu J, Zhao J
International immunopharmacology 2019 Mar;68:234-241
International immunopharmacology 2019 Mar;68:234-241
Augmenter of Liver Regeneration Protects against Ethanol-Induced Acute Liver Injury by Promoting Autophagy.
Liu L, Xie P, Li W, Wu Y, An W
The American journal of pathology 2019 Mar;189(3):552-567
The American journal of pathology 2019 Mar;189(3):552-567
Acid Sphingomyelinase Inhibition Attenuates Cell Death in Mechanically Ventilated Newborn Rat Lung.
Yeganeh B, Lee J, Bilodeau C, Lok I, Ermini L, Ackerley C, Caniggia I, Tibboel J, Kroon A, Post M
American journal of respiratory and critical care medicine 2019 Mar 15;199(6):760-772
American journal of respiratory and critical care medicine 2019 Mar 15;199(6):760-772
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.
Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, Tian Y
Toxins 2019 Jan 15;11(1)
Toxins 2019 Jan 15;11(1)
Autophagy promotes hepatic differentiation of hepatic progenitor cells by regulating the Wnt/β-catenin signaling pathway.
Ma Z, Li F, Chen L, Gu T, Zhang Q, Qu Y, Xu M, Cai X, Lu L
Journal of molecular histology 2019 Feb;50(1):75-90
Journal of molecular histology 2019 Feb;50(1):75-90
Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs.
Zhang X, Liu J, Gu Y, Sun C, Qu F
Cell biology international 2019 Feb;43(2):158-166
Cell biology international 2019 Feb;43(2):158-166
DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats.
Duan J, Deng T, Kang J, Chen M
Environmental pollution (Barking, Essex : 1987) 2019 Feb;245:316-324
Environmental pollution (Barking, Essex : 1987) 2019 Feb;245:316-324
Autophagy is involved in the differentiation of epicardial progenitor cells into vascular smooth muscle cells in mice.
Liu Y, Liu B, Li Y, Li Y, Du J, Deng S, Jing X, She Q
Experimental cell research 2019 Feb 15;375(2):60-71
Experimental cell research 2019 Feb 15;375(2):60-71
Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damage.
Li Y, Wang C, Liu Y, You J, Su G
Tissue & cell 2019 Dec;61:98-108
Tissue & cell 2019 Dec;61:98-108
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy.
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, Yang L
Journal of medicinal food 2019 Dec;22(12):1271-1279
Journal of medicinal food 2019 Dec;22(12):1271-1279
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Gao H, Zhang J, Ren X
Bioscience reports 2019 Dec 20;39(12)
Bioscience reports 2019 Dec 20;39(12)
Nix/BNIP3L-dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke.
Zhang M, Shi R, Zhang Y, Shan H, Zhang Q, Yang X, Li Y, Zhang J
Journal of cellular physiology 2019 Aug;234(8):14210-14220
Journal of cellular physiology 2019 Aug;234(8):14210-14220
Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy.
Wen J, Xu B, Sun Y, Lian M, Li Y, Lin Y, Chen D, Diao Y, Almoiliqy M, Wang L
Pharmacological research 2019 Aug;146:104308
Pharmacological research 2019 Aug;146:104308
Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway.
Li T, Wen L, Cheng B
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
Biochemical and biophysical research communications 2019 Aug 27;516(3):632-638
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury.
Jin J, Sun H, Liu D, Wang H, Liu Q, Chen H, Zhong D, Li G
Neuroscience 2019 Aug 10;413:123-134
Neuroscience 2019 Aug 10;413:123-134
Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain.
Wang C, Fu J, Wang M, Cai Y, Hua X, Du Y, Yang Z, Li Y, Wang Z, Sheng H, Yin N, Liu X, Koehler JE, Yuan C
Cellular microbiology 2019 Apr;21(4):e12984
Cellular microbiology 2019 Apr;21(4):e12984
Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem.
Pan H, Wang H, Yu J, Huang X, Hao Y, Zhang C, Ji W, Yang M, Gong X, Wu X, Chang J
Biomaterials 2019 Apr;199:22-31
Biomaterials 2019 Apr;199:22-31
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)(2)D(3) on the osteoclastogenesis.
Ji L, Gao J, Kong R, Gao Y, Ji X, Zhao D
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice.
Li M, Xu M, Li J, Chen L, Xu D, Tong Y, Zhang J, Wu H, Kong X, Xia Q
Journal of immunology research 2018;2018:9807139
Journal of immunology research 2018;2018:9807139
Di-2-pyridylhydrazone Dithiocarbamate Butyric Acid Ester Exerted Its Proliferative Inhibition against Gastric Cell via ROS-Mediated Apoptosis and Autophagy.
Guo X, Fu Y, Wang Z, Wang T, Li C, Huang T, Gao F, Li C
Oxidative medicine and cellular longevity 2018;2018:4950705
Oxidative medicine and cellular longevity 2018;2018:4950705
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Han T, Guo M, Gan M, Yu B, Tian X, Wang JB
Autophagy 2018;14(12):2035-2048
Autophagy 2018;14(12):2035-2048
Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy.
Zhou ZB, Niu YL, Huang GX, Lu JJ, Chen A, Zhu L
Molecular therapy. Nucleic acids 2018 Sep 7;12:718-729
Molecular therapy. Nucleic acids 2018 Sep 7;12:718-729
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis.
Dai C, Xiao X, Li D, Tun S, Wang Y, Velkov T, Tang S
Cell death & disease 2018 Nov 26;9(12):1164
Cell death & disease 2018 Nov 26;9(12):1164
NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway.
Deng L, Gao X, Liu B, He X, Xu J, Qiang J, Wu Q, Liu S
Cell death & disease 2018 Nov 16;9(12):1143
Cell death & disease 2018 Nov 16;9(12):1143
Mitophagy in three cases of immune-mediated necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: ultrastructural and immunohistochemical studies.
Matsubara S, Bokuda K, Asano Y, Morishima R, Sugaya K, Miyamoto K, Koide R, Komori T, Suzuki S, Nishino I
Neuromuscular disorders : NMD 2018 Mar;28(3):283-288
Neuromuscular disorders : NMD 2018 Mar;28(3):283-288
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β(1) in human lung fibroblasts.
Ghavami S, Yeganeh B, Zeki AA, Shojaei S, Kenyon NJ, Ott S, Samali A, Patterson J, Alizadeh J, Moghadam AR, Dixon IMC, Unruh H, Knight DA, Post M, Klonisch T, Halayko AJ
American journal of physiology. Lung cellular and molecular physiology 2018 Mar 1;314(3):L493-L504
American journal of physiology. Lung cellular and molecular physiology 2018 Mar 1;314(3):L493-L504
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells.
Ren J, Liu Y, Li L, Zhao Y, Li Z, Wu C, Chen L, Hu K
Cell biology international 2018 Feb;42(2):194-204
Cell biology international 2018 Feb;42(2):194-204
Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.
Niu Q, Chen J, Xia T, Li P, Zhou G, Xu C, Zhao Q, Dong L, Zhang S, Wang A
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Environmental pollution (Barking, Essex : 1987) 2018 Feb;233:889-899
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
Li Z, Zhu S, Huang L, Shang M, Yu C, Zhu H, Han D, Huang H, Yu X, Li X
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice.
Zhang X, Liu H, Hao Y, Xu L, Zhang T, Liu Y, Guo L, Zhu L, Pei Z
Lipids in health and disease 2018 Dec 8;17(1):279
Lipids in health and disease 2018 Dec 8;17(1):279
Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment.
Wang L, Li X, Chen C
International immunopharmacology 2018 Aug;61:20-28
International immunopharmacology 2018 Aug;61:20-28
Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer.
Wu Z, Zhu Q, Yin Y, Kang D, Cao R, Tian Q, Zhang Y, Lu S, Liu P
Cancer medicine 2018 Apr;7(4):1546-1559
Cancer medicine 2018 Apr;7(4):1546-1559
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Liu Y, Tang J, Liu D, Zhang L, He Y, Li J, Gao L, Tang D, Jin X, Kong D
Cell death & disease 2018 Apr 1;9(4):419
Cell death & disease 2018 Apr 1;9(4):419
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells.
Zou J, Zhang Y, Sun J, Wang X, Tu H, Geng S, Liu R, Chen Y, Bi Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1812-1821
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1812-1821
Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy.
Yu N, Xiong Y, Wang C
BioMed research international 2017;2017:3692797
BioMed research international 2017;2017:3692797
Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.
Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z, Shen G
Drug design, development and therapy 2017;11:431-439
Drug design, development and therapy 2017;11:431-439
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
He Q, Li Z, Wang Y, Hou Y, Li L, Zhao J
International immunopharmacology 2017 Sep;50:208-215
International immunopharmacology 2017 Sep;50:208-215
miR-361-5p modulates metabolism and autophagy via the Sp1-mediated regulation of PKM2 in prostate cancer.
Ling Z, Liu D, Zhang G, Liang Q, Xiang P, Xu Y, Han C, Tao T
Oncology reports 2017 Sep;38(3):1621-1628
Oncology reports 2017 Sep;38(3):1621-1628
Role of autophagy in cadmium-induced testicular injury.
Wang YJ, Yan J, Yin F, Li L, Qin YG, Meng CY, Lu RF, Guo L
Human & experimental toxicology 2017 Oct;36(10):1039-1048
Human & experimental toxicology 2017 Oct;36(10):1039-1048
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats.
Xue TF, Ding X, Ji J, Yan H, Huang JY, Guo XD, Yang J, Sun XL
Journal of pharmacological sciences 2017 Nov;135(3):105-113
Journal of pharmacological sciences 2017 Nov;135(3):105-113
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Khan SH, Zhao D, Shah SZ, Hassan MF, Zhu T, Song Z, Zhou X, Yang L
Cellular and molecular neurobiology 2017 May;37(4):717-728
Cellular and molecular neurobiology 2017 May;37(4):717-728
miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7.
Hao H, Xia G, Wang C, Zhong F, Liu L, Zhang D
Medical molecular morphology 2017 Jun;50(2):76-85
Medical molecular morphology 2017 Jun;50(2):76-85
Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.
Boeske A, Schwarten M, Ma P, Tusche M, Mötter J, Möller C, Neudecker P, Hoffmann S, Willbold D
Scientific reports 2017 Jul 20;7(1):5979
Scientific reports 2017 Jul 20;7(1):5979
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed ME, Zhu L, Liu TC, Cohen RM, Zhang Q
Neurobiology of aging 2017 Jan;49:165-182
Neurobiology of aging 2017 Jan;49:165-182
Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells.
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, Qaed E, Lin Y, Peng J, Ma X, Zhang J, Wang S, Tang Z
Cell biology international 2017 Dec;41(12):1367-1378
Cell biology international 2017 Dec;41(12):1367-1378
Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate.
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, Zhao Y, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Journal of cellular and molecular medicine 2017 Dec;21(12):3190-3203
Exogenous H(2)S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, Zhang L, Dong S, Yang F, Zhong X, Xu C, Lu F, Zhang W
Cell death & disease 2017 Aug 10;8(8):e2992
Cell death & disease 2017 Aug 10;8(8):e2992
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Han T, Guo M, Zhang T, Gan M, Xie C, Wang JB
Oncotarget 2017 Apr 25;8(17):28063-28073
Oncotarget 2017 Apr 25;8(17):28063-28073
Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy.
Dai C, Tang S, Velkov T, Xiao X
Molecular neurobiology 2016 Sep;53(7):4685-700
Molecular neurobiology 2016 Sep;53(7):4685-700
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Guo YJ, Dong SY, Cui XX, Feng Y, Liu T, Yin M, Kuo SH, Tan EK, Zhao WJ, Wu YC
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Molecular nutrition & food research 2016 Oct;60(10):2161-2175
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, Zhang Z, Lin Y, Peng J, Song Z, Wang S, Tang Z
International immunopharmacology 2016 Nov;40:400-409
International immunopharmacology 2016 Nov;40:400-409
Autophagy and apoptosis induced by Chinese giant salamander (Andrias davidianus) iridovirus (CGSIV).
Du J, Wang L, Wang Y, Shen J, Pan C, Meng Y, Yang C, Ji H, Dong W
Veterinary microbiology 2016 Nov 15;195:87-95
Veterinary microbiology 2016 Nov 15;195:87-95
Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.
Wang K, Zhang C, Bao J, Jia X, Liang Y, Wang X, Chen M, Su H, Li P, Wan JB, He C
Scientific reports 2016 Jun 6;6:26064
Scientific reports 2016 Jun 6;6:26064
Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy.
Kessel D, Evans CL
Photochemistry and photobiology 2016 Jul;92(4):620-3
Photochemistry and photobiology 2016 Jul;92(4):620-3
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, Hang H, Liu S, Chu P, Sun Z, Sun B, Lin Y, Peng J, Han G, Wang S, Tang Z
Chemico-biological interactions 2016 Jan 25;244:94-104
Chemico-biological interactions 2016 Jan 25;244:94-104
Dimethyl α-ketoglutarate reduces CCl(4)-induced liver fibrosis through inhibition of autophagy in hepatic stellate cells.
Zhao J, Peng L, Cui R, Guo X, Yan M
Biochemical and biophysical research communications 2016 Dec 2;481(1-2):90-96
Biochemical and biophysical research communications 2016 Dec 2;481(1-2):90-96
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.
He G, Xu W, Tong L, Li S, Su S, Tan X, Li C
Apoptosis : an international journal on programmed cell death 2016 Apr;21(4):390-403
Apoptosis : an international journal on programmed cell death 2016 Apr;21(4):390-403
Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways.
Su C, Niu P
International journal of clinical and experimental medicine 2015;8(11):20508-15
International journal of clinical and experimental medicine 2015;8(11):20508-15
Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.
Hiyama M, Kusakabe KT, Takeshita A, Sugi S, Kuniyoshi N, Imai H, Kano K, Kiso Y
The Journal of veterinary medical science 2015 Mar;77(3):305-11
The Journal of veterinary medical science 2015 Mar;77(3):305-11
Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
Zhu X, Ruan Z, Yang X, Chu K, Wu H, Li Y, Huang Y
Journal of cellular and molecular medicine 2015 Jan;19(1):257-64
Journal of cellular and molecular medicine 2015 Jan;19(1):257-64
Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation.
Park M, Kim YH, Woo SY, Lee HJ, Yu Y, Kim HS, Park YS, Jo I, Park JW, Jung SC, Lee H, Jeong B, Ryu KH
Scientific reports 2015 Feb 27;5:8616
Scientific reports 2015 Feb 27;5:8616
Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling.
Yamani L, Li B, Larose L
Cellular signalling 2015 Dec;27(12):2555-67
Cellular signalling 2015 Dec;27(12):2555-67
Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response.
Yeganeh B, Rezaei Moghadam A, Alizadeh J, Wiechec E, Alavian SM, Hashemi M, Geramizadeh B, Samali A, Bagheri Lankarani K, Post M, Peymani P, Coombs KM, Ghavami S
World journal of gastroenterology 2015 Dec 21;21(47):13225-39
World journal of gastroenterology 2015 Dec 21;21(47):13225-39
Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways.
Dai C, Li J, Tang S, Li J, Xiao X
Antimicrobial agents and chemotherapy 2014 Jul;58(7):4075-85
Antimicrobial agents and chemotherapy 2014 Jul;58(7):4075-85
Inhibition of autophagy promotes caspase-mediated apoptosis by tunicamycin in HepG2 cells.
Zhang S, Wang C, Tang S, Deng S, Zhou Y, Dai C, Yang X, Xiao X
Toxicology mechanisms and methods 2014 Dec;24(9):654-65
Toxicology mechanisms and methods 2014 Dec;24(9):654-65
Modulating autophagy improves cardiac function in a rat model of early-stage dilated cardiomyopathy.
Xie K, Jin B, Li Y, Luo X, Zhu J, Ma D, Shi H
Cardiology 2013;125(1):60-8
Cardiology 2013;125(1):60-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 18725-1-AP(MAP1LC3B-Specific antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MAP1LC3B antibody 18725-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LC3B-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human LC3B-Specific. This antibody recognizes human, mouse, rat antigen. The LC3B-Specific antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 18725-1-AP(MAP1LC3B-Specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 18725-1-AP(MAP1LC3B-Specific antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
