Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
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- Product number
- M01524 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-LC3B MAP1LC3B Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for LC3B/MAP1LC3B detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, WB. Reactive species: Human, Mouse, Rat LC3B/MAP1LC3B information: Molecular Weight: 14688 MW; Subcellular Localization: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome . LC3-II binds to the autophagic membranes. Localizes also to discrete punctae along the ciliary axoneme (By similarity); Tissue Specificity: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- IEC-13
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references VD(3)/VDR attenuates bisphenol A-induced impairment in mouse Leydig cells via regulation of autophagy.
STAM2 negatively regulates the MyD88-mediated NF-κB signaling pathway in miiuy croaker, Miichthys miiuy.
Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy.
Ruthenium red alleviates post-resuscitation myocardial dysfunction by upregulating mitophagy through inhibition of USP33 in a cardiac arrest rat model.
m6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR.
Lower dose of metformin combined with artesunate induced autophagy-dependent apoptosis of glioblastoma by activating ROS-AMPK-mTOR axis.
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
ACKR4a induces autophagy to block NF-κB signaling and apoptosis to facilitate Vibrio harveyi infection.
The mtDNA-STING pathway plays an important role in both navitoclax- and S63845-induced autophagy and enhances cell death.
eIF3k inhibits NF-κB signaling by targeting MyD88 for ATG5-mediated autophagic degradation in teleost fish.
Polyphyllin I Promotes Autophagic Cell Death and Apoptosis of Colon Cancer Cells via the ROS-Inhibited AKT/mTOR Pathway.
Cordycepin alleviated metabolic inflammation in Western diet-fed mice by targeting intestinal barrier integrity and intestinal flora.
Rhodiola crenulata extract decreases fatty acid oxidation and autophagy to ameliorate pulmonary arterial hypertension by targeting inhibiton of acylcarnitine in rats.
Cu-Doped-ZnO Nanocrystals Induce Hepatocyte Autophagy by Oxidative Stress Pathway.
Exogenous Hydrogen Sulfide Ameliorates Diabetic Myocardial Fibrosis by Inhibiting Cell Aging Through SIRT6/AMPK Autophagy.
Selective binding of mitophagy receptor protein Bcl-rambo to LC3/GABARAP family proteins.
β -Cypermethrin promotes the adipogenesis of 3T3-L1 cells via inducing autophagy and shaping an adipogenesis-friendly microenvironment.
Hydroxytyrosol prevents dermal papilla cells inflammation under oxidative stress by inducing autophagy.
Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress.
Huganpian, a traditional chinese medicine, inhibits liver cancer growth in vitro and in vivo by inducing autophagy and cell cycle arrest.
Expression of miR-551b and its effect on apoptosis in human gastric carcinoma.
Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation.
Antagomirs Targeting MiroRNA-134 Attenuates Epilepsy in Rats through Regulation of Oxidative Stress, Mitochondrial Functions and Autophagy.
Regulation of autophagy by AMP-activated protein kinase/sirtuin 1 pathway reduces spinal cord neurons damage.
Wang L, Zhuang J, Xue Z, Lu H, Zeng W, Zhang T
Journal of food science 2024 Jun;89(6):3858-3870
Journal of food science 2024 Jun;89(6):3858-3870
STAM2 negatively regulates the MyD88-mediated NF-κB signaling pathway in miiuy croaker, Miichthys miiuy.
Xu Y, Li W, Chen Y, Xu T, Sun Y
Fish & shellfish immunology 2024 Jun;149:109550
Fish & shellfish immunology 2024 Jun;149:109550
Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy.
Feng Z, Zhang S, Han Q, Chu T, Wang H, Yu L, Zhang W, Liu J, Liang W, Xue J, Wu X, Zhang C, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155647
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155647
Ruthenium red alleviates post-resuscitation myocardial dysfunction by upregulating mitophagy through inhibition of USP33 in a cardiac arrest rat model.
Zhang F, Ye Z, Ran Y, Liu C, Zhang M, Xu X, Song F, Yao L
European journal of pharmacology 2024 Jul 5;974:176633
European journal of pharmacology 2024 Jul 5;974:176633
m6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR.
Liang DM, Li YJ, Zhang JX, Shen HH, Wu CX, Xie N, Liang Y, Li YM, Xue JN, Sun HF, Wang Q, Yang J, Li XH, Wang PY, Xie SY
Communications biology 2024 Feb 21;7(1):215
Communications biology 2024 Feb 21;7(1):215
Lower dose of metformin combined with artesunate induced autophagy-dependent apoptosis of glioblastoma by activating ROS-AMPK-mTOR axis.
Ding W, Liao L, Liu J, Zhao J, Tang Q, Liao Y
Experimental cell research 2023 Sep 1;430(1):113691
Experimental cell research 2023 Sep 1;430(1):113691
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Fan R, Wang S, Wu Y, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L, Wang Y, Dai F
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
ACKR4a induces autophagy to block NF-κB signaling and apoptosis to facilitate Vibrio harveyi infection.
Chen Y, Cao B, Zheng W, Xu T
iScience 2023 Mar 17;26(3):106105
iScience 2023 Mar 17;26(3):106105
The mtDNA-STING pathway plays an important role in both navitoclax- and S63845-induced autophagy and enhances cell death.
Jia J, Li M, Li Y, Xiao J, Dai H
Cell biology and toxicology 2023 Dec;39(6):2821-2839
Cell biology and toxicology 2023 Dec;39(6):2821-2839
eIF3k inhibits NF-κB signaling by targeting MyD88 for ATG5-mediated autophagic degradation in teleost fish.
Chen Y, Cao B, Zheng W, Sun Y, Xu T
The Journal of biological chemistry 2022 Mar;298(3):101730
The Journal of biological chemistry 2022 Mar;298(3):101730
Polyphyllin I Promotes Autophagic Cell Death and Apoptosis of Colon Cancer Cells via the ROS-Inhibited AKT/mTOR Pathway.
Luo Q, Jia L, Huang C, Qi Q, Jahangir A, Xia Y, Liu W, Shi R, Tang L, Chen Z
International journal of molecular sciences 2022 Aug 19;23(16)
International journal of molecular sciences 2022 Aug 19;23(16)
Cordycepin alleviated metabolic inflammation in Western diet-fed mice by targeting intestinal barrier integrity and intestinal flora.
Chen J, Wang M, Zhang P, Li H, Qu K, Xu R, Guo N, Zhu H
Pharmacological research 2022 Apr;178:106191
Pharmacological research 2022 Apr;178:106191
Rhodiola crenulata extract decreases fatty acid oxidation and autophagy to ameliorate pulmonary arterial hypertension by targeting inhibiton of acylcarnitine in rats.
Ren HH, Niu Z, Guo R, Fu M, Li HR, Zhang XY, Yao L
Chinese journal of natural medicines 2021 Feb;19(2):120-133
Chinese journal of natural medicines 2021 Feb;19(2):120-133
Cu-Doped-ZnO Nanocrystals Induce Hepatocyte Autophagy by Oxidative Stress Pathway.
Bai Q, Wang Y, Duan L, Xu X, Hu Y, Yang Y, Zhang L, Liu Z, Bao H, Liu T
Nanomaterials (Basel, Switzerland) 2021 Aug 17;11(8)
Nanomaterials (Basel, Switzerland) 2021 Aug 17;11(8)
Exogenous Hydrogen Sulfide Ameliorates Diabetic Myocardial Fibrosis by Inhibiting Cell Aging Through SIRT6/AMPK Autophagy.
Li Y, Liu M, Song X, Zheng X, Yi J, Liu D, Wang S, Chu C, Yang J
Frontiers in pharmacology 2020;11:1150
Frontiers in pharmacology 2020;11:1150
Selective binding of mitophagy receptor protein Bcl-rambo to LC3/GABARAP family proteins.
Li M, Jia J, Zhang X, Dai H
Biochemical and biophysical research communications 2020 Sep 10;530(1):292-300
Biochemical and biophysical research communications 2020 Sep 10;530(1):292-300
β -Cypermethrin promotes the adipogenesis of 3T3-L1 cells via inducing autophagy and shaping an adipogenesis-friendly microenvironment.
He B, Wang X, Jin X, Xue Z, Zhu J, Wang C, Jin Y, Fu Z
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):821-831
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):821-831
Hydroxytyrosol prevents dermal papilla cells inflammation under oxidative stress by inducing autophagy.
Chen Q, Sun T, Wang J, Jia J, Yi YH, Chen YX, Miao Y, Hu ZQ
Journal of biochemical and molecular toxicology 2019 Sep;33(9):e22377
Journal of biochemical and molecular toxicology 2019 Sep;33(9):e22377
Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress.
He B, Wang X, Zhu J, Kong B, Wei L, Jin Y, Fu Z
Environmental pollution (Barking, Essex : 1987) 2019 Jul;250:416-425
Environmental pollution (Barking, Essex : 1987) 2019 Jul;250:416-425
Huganpian, a traditional chinese medicine, inhibits liver cancer growth in vitro and in vivo by inducing autophagy and cell cycle arrest.
Gao X, Wang Y, Li Y, Wang Y, Yan M, Sun H, Chen S, Pan X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109469
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109469
Expression of miR-551b and its effect on apoptosis in human gastric carcinoma.
Wang Y, Fan X, Xu F, Zhang P, Wei Y, Cheng S, Zhao P
International journal of clinical and experimental pathology 2018;11(5):2912-2919
International journal of clinical and experimental pathology 2018;11(5):2912-2919
Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation.
Liu F, Zhang J, Qin L, Yang Z, Xiong J, Zhang Y, Li R, Li S, Wang H, Yu B, Zhao W, Wang W, Li Z, Liu J
Aging 2018 Dec 12;10(12):3806-3820
Aging 2018 Dec 12;10(12):3806-3820
Antagomirs Targeting MiroRNA-134 Attenuates Epilepsy in Rats through Regulation of Oxidative Stress, Mitochondrial Functions and Autophagy.
Sun J, Gao X, Meng D, Xu Y, Wang X, Gu X, Guo M, Shao X, Yan H, Jiang C, Zheng Y
Frontiers in pharmacology 2017;8:524
Frontiers in pharmacology 2017;8:524
Regulation of autophagy by AMP-activated protein kinase/sirtuin 1 pathway reduces spinal cord neurons damage.
Yan P, Bai L, Lu W, Gao Y, Bi Y, Lv G
Iranian journal of basic medical sciences 2017 Sep;20(9):1029-1036
Iranian journal of basic medical sciences 2017 Sep;20(9):1029-1036
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