Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 14175-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14175-1-AP, RRID:AB_2171592
- Product name
- Liprin Alpha 1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Liprin Alpha 1 antibody (Cat. #14175-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Enhanced structure and function of human pluripotent stem cell-derived beta-cells cultured on extracellular matrix.
Structural basis of liprin-α-promoted LAR-RPTP clustering for modulation of phosphatase activity.
The ERC1 scaffold protein implicated in cell motility drives the assembly of a liquid phase.
Characterization of the polarized endothelial secretome.
Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton.
Identification of a membrane-less compartment regulating invadosome function and motility.
A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence.
Cell polarity defines three distinct domains in pancreatic β-cells.
Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.
Liprin-α1 and ERC1 control cell edge dynamics by promoting focal adhesion turnover.
PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.
Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.
Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery.
Liprin-α1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.
Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast.
Singh R, Cottle L, Loudovaris T, Xiao D, Yang P, Thomas HE, Kebede MA, Thorn P
Stem cells translational medicine 2021 Mar;10(3):492-505
Stem cells translational medicine 2021 Mar;10(3):492-505
Structural basis of liprin-α-promoted LAR-RPTP clustering for modulation of phosphatase activity.
Xie X, Luo L, Liang M, Zhang W, Zhang T, Yu C, Wei Z
Nature communications 2020 Jan 10;11(1):169
Nature communications 2020 Jan 10;11(1):169
The ERC1 scaffold protein implicated in cell motility drives the assembly of a liquid phase.
Sala K, Corbetta A, Minici C, Tonoli D, Murray DH, Cammarota E, Ribolla L, Ramella M, Fesce R, Mazza D, Degano M, de Curtis I
Scientific reports 2019 Sep 19;9(1):13530
Scientific reports 2019 Sep 19;9(1):13530
Characterization of the polarized endothelial secretome.
Wei H, Sundararaman A, Dickson E, Rennie-Campbell L, Cross E, Heesom KJ, Mellor H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12277-12287
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Nov;33(11):12277-12287
Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton.
Pehkonen H, Lento M, von Nandelstadh P, Filippou A, Grénman R, Lehti K, Monni O
Cell communication and signaling : CCS 2018 Jul 13;16(1):41
Cell communication and signaling : CCS 2018 Jul 13;16(1):41
Identification of a membrane-less compartment regulating invadosome function and motility.
Sala K, Raimondi A, Tonoli D, Tacchetti C, de Curtis I
Scientific reports 2018 Jan 18;8(1):1164
Scientific reports 2018 Jan 18;8(1):1164
A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence.
Franchi SA, Macco R, Astro V, Tonoli D, Savino E, Valtorta F, Sala K, Botta M, de Curtis I
Frontiers in cellular neuroscience 2017;11:423
Frontiers in cellular neuroscience 2017;11:423
Cell polarity defines three distinct domains in pancreatic β-cells.
Gan WJ, Zavortink M, Ludick C, Templin R, Webb R, Webb R, Ma W, Poronnik P, Parton RG, Gaisano HY, Shewan AM, Thorn P
Journal of cell science 2017 Jan 1;130(1):143-151
Journal of cell science 2017 Jan 1;130(1):143-151
Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.
Franchi SA, Astro V, Macco R, Tonoli D, Barnier JV, Botta M, de Curtis I
Frontiers in cellular neuroscience 2016;10:289
Frontiers in cellular neuroscience 2016;10:289
Liprin-α1 and ERC1 control cell edge dynamics by promoting focal adhesion turnover.
Astro V, Tonoli D, Chiaretti S, Badanai S, Sala K, Zerial M, de Curtis I
Scientific reports 2016 Sep 23;6:33653
Scientific reports 2016 Sep 23;6:33653
PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis.
Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D
Nature communications 2016 Nov 23;7:13546
Nature communications 2016 Nov 23;7:13546
Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.
Chiaretti S, Astro V, Chiricozzi E, de Curtis I
Biology of the cell 2016 Mar;108(3):65-75
Biology of the cell 2016 Mar;108(3):65-75
Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery.
Pehkonen H, von Nandelstadh P, Karhemo PR, Lepikhova T, Grenman R, Lehti K, Monni O
Scientific reports 2016 Apr 14;6:24486
Scientific reports 2016 Apr 14;6:24486
Liprin-α1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.
Astro V, Chiaretti S, Magistrati E, Fivaz M, de Curtis I
Journal of cell science 2014 Sep 1;127(Pt 17):3862-76
Journal of cell science 2014 Sep 1;127(Pt 17):3862-76
Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast.
Choi EJ, Yun JA, Jabeen S, Jeon EK, Won HS, Ko YH, Kim SY
World journal of surgical oncology 2014 May 1;12:137
World journal of surgical oncology 2014 May 1;12:137
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14175-1-AP(PPFIA1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using PPFIA1 antibody 14175-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 14175-1-AP(PPFIA1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 14175-1-AP(PPFIA1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue