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- References [9]
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- Product number
- 14917-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14917-1-AP, RRID:AB_2250635
- Product name
- MEPCE antibody
- Antibody type
- Polyclonal
- Description
- MEPCE antibody (Cat. #14917-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity.
N(6)-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation.
7SK methylation by METTL3 promotes transcriptional activity.
HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation.
Interaction of 7SK with the Smn complex modulates snRNP production.
de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation.
Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex.
Human METTL16 is a N(6)-methyladenosine (m(6)A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.
7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts.
Meng Y, Iyamu ID, Ahmed NAM, Huang R
ACS chemical biology 2024 Jan 19;19(1):89-100
ACS chemical biology 2024 Jan 19;19(1):89-100
N(6)-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation.
Wang Y, Traugot CM, Bubenik JL, Li T, Sheng P, Hiers NM, Fernandez P, Li L, Bian J, Swanson MS, Xie M
Molecular cell 2023 Nov 2;83(21):3818-3834.e7
Molecular cell 2023 Nov 2;83(21):3818-3834.e7
7SK methylation by METTL3 promotes transcriptional activity.
Perez-Pepe M, Desotell AW, Li H, Li W, Han B, Lin Q, Klein DE, Liu Y, Goodarzi H, Alarcón CR
Science advances 2023 May 10;9(19):eade7500
Science advances 2023 May 10;9(19):eade7500
HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation.
Isa NF, Bensaude O, Aziz NC, Murphy S
Vaccines 2021 Sep 22;9(10)
Vaccines 2021 Sep 22;9(10)
Interaction of 7SK with the Smn complex modulates snRNP production.
Ji C, Bader J, Ramanathan P, Hennlein L, Meissner F, Jablonka S, Mann M, Fischer U, Sendtner M, Briese M
Nature communications 2021 Feb 24;12(1):1278
Nature communications 2021 Feb 24;12(1):1278
de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation.
Schneeberger PE, Bierhals T, Neu A, Hempel M, Kutsche K
Scientific reports 2019 Aug 29;9(1):12516
Scientific reports 2019 Aug 29;9(1):12516
Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex.
Von Dwingelo J, Chung IYW, Price CT, Li L, Jones S, Cygler M, Abu Kwaik Y
mBio 2019 Aug 27;10(4)
mBio 2019 Aug 27;10(4)
Human METTL16 is a N(6)-methyladenosine (m(6)A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.
Warda AS, Kretschmer J, Hackert P, Lenz C, Urlaub H, Höbartner C, Sloan KE, Bohnsack MT
EMBO reports 2017 Nov;18(11):2004-2014
EMBO reports 2017 Nov;18(11):2004-2014
7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts.
Mizutani T, Ishizaka A, Suzuki Y, Iba H
FEBS letters 2014 May 2;588(9):1630-6
FEBS letters 2014 May 2;588(9):1630-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MEPCE antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MEPCE. This antibody recognizes human, mouse, rat antigen. The MEPCE antibody has been validated for the following applications: ELISA, WB analysis.
