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- Antibody Data
- Antigen structure
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- ELISA [1]
- Flow cytometry [3]
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- Product number
- Ab182880 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Tilvestamab (anti-AXL)
- Antibody type
- Recombinant
- Description
- Tilvestamab (anti-AXL) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab (anti-AXL) significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab (anti-AXL) can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas.Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
- Reactivity
- Human
- Conjugate
- Unconjugated
- Vial size
- 100_g,10mg,1mg,5mg
- Concentration
- Lot by Lot
- Storage
- Store at -80_ for 24Êmonths.ÊUpon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Tilvestamab (anti-AXL) (Ab182880) - ELISA Immobilized Human AXL Fc tag at 2.0 μg/mL can bind Tilvestamab (anti-AXL) (Ab182880) with the EC₅₀ of 3.40 ng/mL.
Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Tilvestamab (anti-AXL) (Ab182880) - Flow Cytometry Flow Cytometry analysis of A549 cells labelling AXL (red) with Tilvestamab (anti-AXL) (Ab182880). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Tilvestamab (anti-AXL) (Ab182880) - Flow Cytometry Flow Cytometry analysis of HeLa cells labelling AXL (red) with Tilvestamab (anti-AXL) (Ab182880). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Tilvestamab (anti-AXL) (Ab182880) - Flow Cytometry Human AXL HEK293 cells were stained with Tilvestamab (anti-AXL) (Ab182880) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC₅₀=73.18 ng/mL.
