67363-1-Ig

antibody from Proteintech Group

Targeting: SLC9A1 APNH, NHE1, PPP1R143

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67363-1-Ig

Provider

Proteintech Group

Product name

NHE1 antibody

Antibody type

Monoclonal

Description

NHE1 antibody (Cat. #67363-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3D9F3

Vial size

20ul, 150ul

References

Submitted references

Cystinosin regulates Na(+)/H(+) exchanger 3 trafficking and function in kidney proximal tubular cells.

Khare V, Farré JC, Ait Kbaich M, Rocca CJ, Tang C, Ma X, Biederman K, Mathur I, Badell-Grau RA, Sivakumar A, Chen R, Catz SD, Cherqui S
EMBO reports 2026 Apr;27(8):2088-2117

---

Necrosis by sodium overload-associated genes TRPM4 and SLC9A1: biological roles and clinical implications in breast cancer progression.

Zhu Y, Guo Y, Su Y, Zhang Z, Lu Y, Zhang X, Pang H
Frontiers in immunology 2025;16:1623511

---

Cinobufagin overcomes bortezomib resistance in multiple myeloma strains by targeting SEC62/TRPM4-mediated NECSO.

Yin Z, Li G, Zhong Q, Zhang X, Ou R, Shen H, Huang J, Mahati S, Liu Z, Zhu Y, Zhang Q, Liu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157171

---

Cystinosin is involved in Na(+)/H(+) Exchanger 3 trafficking in the proximal tubular cells: new insights in the renal Fanconi syndrome in cystinosis.

Khare V, Farre JC, Rocca C, Kbaich MA, Tang C, Ma X, Beiderman K, Mathur I, Badell-Grau RA, Sivakumar A, Chen R, Catz SD, Cherqui S
bioRxiv : the preprint server for biology 2025 Feb 12;

---

A Human Engineered Heart Tissue-Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin.

Cai L, Zhao Y, Li Z, Xiao L, Wu Y, Wang S, Liu Q, Ye Y, Guo Y, Zhang D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e03173

---

Puerarin inhibits NHE1 activity by interfering with the p38 pathway and attenuates mitochondrial damage induced by myocardial calcium overload in heart failure rats.

Pan G, Cui B, Han M, Lin L, Li Y, Wang L, Guo S, Yin Y, Zhan H, Li P
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):270-279

---

Mitochondrial transplantation rescues Ca(2+) homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy.

Li S, Zhang J, Fu W, Cao J, Li Z, Tian X, Yang M, Zhao J, Wang C, Liu Y, Liu M, Zhao X, Li X, Dong J, Qi Y
Cell reports 2024 Dec 24;43(12):115065

---

Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC.

Lu H, Liu H, Yan R, Ma W, Liu H, Liu R, Sun Y, Ye L, Gao P, Jia W, Zhang P, Zhang H
Cell reports 2024 Dec 24;43(12):114996

---

An abnormal LPA/LPAR1-NHE1 axis leads to the autophagy deficiency of trophoblast cells in recurrent spontaneous abortion.

Chen M, Shi JL, Zheng ZM, Lin Z, Li MQ, Shao J
Reproduction (Cambridge, England) 2023 Nov 1;166(5):357-368

---

Direct cardio-protection of Dapagliflozin against obesity-related cardiomyopathy via NHE1/MAPK signaling.

Lin K, Yang N, Luo W, Qian JF, Zhu WW, Ye SJ, Yuan CX, Xu DY, Liang G, Huang WJ, Shan PR
Acta pharmacologica Sinica 2022 Oct;43(10):2624-2635