AF2306

antibody from R&D Systems

Targeting: IL17C CX2, IL-17C, IL-21, MGC126884, MGC138401

Western blot (Data presented on provider website)

Antibody Data

Product number

AF2306

Provider

R&D Systems

Product name

Mouse IL-17C Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse IL-17C in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human IL-17C is observed, and less than 5% cross-reactivity with recombinant mouse (rm) IL-17D and rmIL-17F is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Antigen sequence

NP_665833


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

The roles of IL-17C in T cell-dependent and -independent inflammatory diseases.

Yamaguchi S, Nambu A, Numata T, Yoshizaki T, Narushima S, Shimura E, Hiraishi Y, Arae K, Morita H, Matsumoto K, Hisatome I, Sudo K, Nakae S
Scientific reports 2018 Oct 24;8(1):15750

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IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.

Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):7128-36

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IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.

Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):7128-36