AF3220

antibody from Novus Biologicals

Targeting: MEP1A PPHA

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

AF3220

Provider

Novus Biologicals

Product name

Goat Polyclonal Meprin alpha Subunit/MEP1A Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human Meprin alpha Subunit/MEP1A in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse MEP1A and recombinant human MEP1B is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Tracking cellular and molecular changes in a species-specific manner during experimental tumor progression in vivo.

Indersie E, Hooks KB, Capdevielle C, Fabre M, Dugot-Senant N, Desplat A, Lepreux S, Merched A, Grosset CF, Hagedorn M
Oncotarget 2018 Mar 23;9(22):16149-16162

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Meprin β contributes to collagen deposition in lung fibrosis.

Biasin V, Wygrecka M, Marsh LM, Becker-Pauly C, Brcic L, Ghanim B, Klepetko W, Olschewski A, Kwapiszewska G
Scientific reports 2017 Jan 6;7:39969

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ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.

Herzog C, Haun RS, Ludwig A, Shah SV, Kaushal GP
The Journal of biological chemistry 2014 May 9;289(19):13308-22