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- References [20]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13363-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13363-1-AP, RRID:AB_2088552
- Product name
- CYP11A1 antibody
- Antibody type
- Polyclonal
- Description
- CYP11A1 antibody (Cat. #13363-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prenatal exposure to propylparaben at human-relevant doses accelerates ovarian aging in adult mice.
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Proteomics analysis reveals the effect of 1α,25(OH)2VD3-glycosides on development of early testes in piglets.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
PRMT5 regulates ovarian follicle development by facilitating Wt1 translation.
CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D.
La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Bisphenol A decreases progesterone synthesis in human ovarian granulosa cells.
Genipin improves reproductive health problems caused by circadian disruption in male mice.
Oxidized-LDL inhibits testosterone biosynthesis by affecting mitochondrial function and the p38 MAPK/COX-2 signaling pathway in Leydig cells.
Proteomic analysis of mouse ovaries during the prepubertal stages.
The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement.
Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.
An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues.
1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter.
Ovarian-like differentiation in eutopic and ectopic endometrioses with aberrant FSH receptor, INSL3 and GATA4/6 expression.
Mitochondria-associated endoplasmic reticulum membrane (MAM) regulates steroidogenic activity via steroidogenic acute regulatory protein (StAR)-voltage-dependent anion channel 2 (VDAC2) interaction.
Pregnenolone can protect the brain from cannabis intoxication.
Immunohistochemical Characterization of S100A6 in the Murine Ovary.
Li M, Zhou S, Wu Y, Li Y, Yan W, Guo Q, Xi Y, Chen Y, Li Y, Wu M, Zhang J, Wei J, Wang S
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117254
Environmental pollution (Barking, Essex : 1987) 2021 Sep 15;285:117254
An integrated RNA-Seq and network study reveals that valproate inhibited progesterone production in human granulosa cells.
Li S, Qi J, Sun Y, Gao X, Ma J, Zhao S
The Journal of steroid biochemistry and molecular biology 2021 Nov;214:105991
The Journal of steroid biochemistry and molecular biology 2021 Nov;214:105991
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Proteomics analysis reveals the effect of 1α,25(OH)2VD3-glycosides on development of early testes in piglets.
Chen H, Bühler K, Zhu Y, Nie X, Liu W
Scientific reports 2021 May 31;11(1):11341
Scientific reports 2021 May 31;11(1):11341
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
PRMT5 regulates ovarian follicle development by facilitating Wt1 translation.
Chen M, Dong F, Chen M, Shen Z, Wu H, Cen C, Cui X, Bao S, Gao F
eLife 2021 Aug 27;10
eLife 2021 Aug 27;10
CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D.
Wang X, Li M, Zhang X, Li Y, He G, Dinnyés A, Sun Q, Xu W
Frontiers in molecular biosciences 2020;7:608447
Frontiers in molecular biosciences 2020;7:608447
La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, An T, Chen Y, Zhang X
International journal of nanomedicine 2020;15:3415-3431
International journal of nanomedicine 2020;15:3415-3431
Bisphenol A decreases progesterone synthesis in human ovarian granulosa cells.
Qi J, Liu L, Yang J, Gao X, Zhang W
Birth defects research 2020 Dec;112(20):1843-1849
Birth defects research 2020 Dec;112(20):1843-1849
Genipin improves reproductive health problems caused by circadian disruption in male mice.
Xu Y, Wang L, Cao S, Hu R, Liu R, Hua K, Guo Z, Di HJ, Hu Z
Reproductive biology and endocrinology : RB&E 2020 Dec 11;18(1):122
Reproductive biology and endocrinology : RB&E 2020 Dec 11;18(1):122
Oxidized-LDL inhibits testosterone biosynthesis by affecting mitochondrial function and the p38 MAPK/COX-2 signaling pathway in Leydig cells.
Jing J, Ding N, Wang D, Ge X, Ma J, Ma R, Huang X, Jueraitetibaike K, Liang K, Wang S, Cao S, Zhao AZ, Yao B
Cell death & disease 2020 Aug 14;11(8):626
Cell death & disease 2020 Aug 14;11(8):626
Proteomic analysis of mouse ovaries during the prepubertal stages.
Xiong J, Wu M, Zhang Q, Zhang C, Xiong G, Ma L, Lu Z, Wang S
Experimental cell research 2019 Apr 15;377(1-2):36-46
Experimental cell research 2019 Apr 15;377(1-2):36-46
The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement.
Tu X, Liu M, Tang J, Zhang Y, Shi Y, Yu L, Sun Z
Reproductive biology and endocrinology : RB&E 2018 May 4;16(1):44
Reproductive biology and endocrinology : RB&E 2018 May 4;16(1):44
Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.
Liu XM, Zhang YL, Ji SY, Zhao LW, Shang WN, Li D, Chen Z, Tong C, Fan HY
Endocrinology 2017 Nov 1;158(11):3988-3999
Endocrinology 2017 Nov 1;158(11):3988-3999
An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues.
Rajapaksha M, Kaur J, Prasad M, Pawlak KJ, Marshall B, Perry EW, Whittal RM, Bose HS
Molecular and cellular biology 2016 Jan 19;36(6):1032-47
Molecular and cellular biology 2016 Jan 19;36(6):1032-47
1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter.
Schedel M, Jia Y, Michel S, Takeda K, Domenico J, Joetham A, Ning F, Strand M, Han J, Wang M, Lucas JJ, Vogelberg C, Kabesch M, O'Connor BP, Gelfand EW
Nature communications 2016 Jan 11;7:10213
Nature communications 2016 Jan 11;7:10213
Ovarian-like differentiation in eutopic and ectopic endometrioses with aberrant FSH receptor, INSL3 and GATA4/6 expression.
Fouquet B, Santulli P, Noel JC, Misrahi M
BBA clinical 2016 Dec;6:143-152
BBA clinical 2016 Dec;6:143-152
Mitochondria-associated endoplasmic reticulum membrane (MAM) regulates steroidogenic activity via steroidogenic acute regulatory protein (StAR)-voltage-dependent anion channel 2 (VDAC2) interaction.
Prasad M, Kaur J, Pawlak KJ, Bose M, Whittal RM, Bose HS
The Journal of biological chemistry 2015 Jan 30;290(5):2604-16
The Journal of biological chemistry 2015 Jan 30;290(5):2604-16
Pregnenolone can protect the brain from cannabis intoxication.
Vallée M, Vitiello S, Bellocchio L, Hébert-Chatelain E, Monlezun S, Martin-Garcia E, Kasanetz F, Baillie GL, Panin F, Cathala A, Roullot-Lacarrière V, Fabre S, Hurst DP, Lynch DL, Shore DM, Deroche-Gamonet V, Spampinato U, Revest JM, Maldonado R, Reggio PH, Ross RA, Marsicano G, Piazza PV
Science (New York, N.Y.) 2014 Jan 3;343(6166):94-8
Science (New York, N.Y.) 2014 Jan 3;343(6166):94-8
Immunohistochemical Characterization of S100A6 in the Murine Ovary.
Hanaue M, Miwa N, Takamatsu K
Acta histochemica et cytochemica 2012 Feb 29;45(1):9-14
Acta histochemica et cytochemica 2012 Feb 29;45(1):9-14
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 13363-1-AP(CYP11A1 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 13363-1-AP(CYP11A1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CYP11A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CYP11A1. This antibody recognizes human antigen. The CYP11A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
