Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN2840619 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Melanoma Antigen Family A, 3 (MAGEA3) (AA 283-314), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 283-314, C-Term
- Antibody clone number
- RB2084
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references MAGE-C1/CT7 is the dominant cancer-testis antigen targeted by humoral immune responses in patients with multiple myeloma.
MAD-CT-2 identified as a novel melanoma cancer-testis antigen using phage immunoblot analysis.
The cancer/testis antigen melanoma-associated antigen-A3/A6 is a novel target of fibroblast growth factor receptor 2-IIIb through histone H3 modifications in thyroid cancer.
Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3.
Detection of multiple melanoma-associated markers in melanoma cell lines by RT in situ PCR.
The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.
Curioni-Fontecedro A, Knights AJ, Tinguely M, Nuber N, Schneider C, Thomson CW, von Boehmer L, Bossart W, Pahlich S, Gehring H, Moch H, Renner C, Knuth A, Zippelius A
Leukemia 2008 Aug;22(8):1646-8
Leukemia 2008 Aug;22(8):1646-8
MAD-CT-2 identified as a novel melanoma cancer-testis antigen using phage immunoblot analysis.
Dubovsky JA, Albertini MR, McNeel DG
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007 Oct;30(7):675-83
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007 Oct;30(7):675-83
The cancer/testis antigen melanoma-associated antigen-A3/A6 is a novel target of fibroblast growth factor receptor 2-IIIb through histone H3 modifications in thyroid cancer.
Kondo T, Zhu X, Asa SL, Ezzat S
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Aug 15;13(16):4713-20
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Aug 15;13(16):4713-20
Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3.
Consogno G, Manici S, Facchinetti V, Bachi A, Hammer J, Conti-Fine BM, Rugarli C, Traversari C, Protti MP
Blood 2003 Feb 1;101(3):1038-44
Blood 2003 Feb 1;101(3):1038-44
Detection of multiple melanoma-associated markers in melanoma cell lines by RT in situ PCR.
Guo J, Wen DR, Huang RR, Paul E, Wünsch P, Itakura E, Cochran AJ
Experimental and molecular pathology 2003 Apr;74(2):140-7
Experimental and molecular pathology 2003 Apr;74(2):140-7
The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.
Rogner UC, Wilke K, Steck E, Korn B, Poustka A
Genomics 1995 Oct 10;29(3):725-31
Genomics 1995 Oct 10;29(3):725-31
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.
van der Bruggen P, Traversari C, Chomez P, Lurquin C, De Plaen E, Van den Eynde B, Knuth A, Boon T
Science (New York, N.Y.) 1991 Dec 13;254(5038):1643-7
Science (New York, N.Y.) 1991 Dec 13;254(5038):1643-7
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- Experimental details
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS