AMM02286G

antibody from Leading Biology

Targeting: MAGEA3 CT1.3, HIP8, HYPD, MAGE3, MGC14613

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02286G

Provider

Leading Biology

Product name

MAGEA3 Antibody (clone 4E2)

Antibody type

Monoclonal

Description

Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

4E2

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.