Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393401 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-WAS Protein Family, Member 2 (WASF2) (AA 73-173) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 73-173
- Isotype
- IgG
- Antibody clone number
- 8E7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate.
Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2.
Activation of the WAVE complex by coincident signals controls actin assembly.
Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex.
BetaPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport.
Takahashi K, Tanaka T, Suzuki K
Cellular signalling 2010 Mar;22(3):510-8
Cellular signalling 2010 Mar;22(3):510-8
Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2.
Cai X, Xiao T, James SY, Da J, Lin D, Liu Y, Zheng Y, Zou S, Di X, Guo S, Han N, Lu YJ, Cheng S, Gao Y, Zhang K
Lung cancer (Amsterdam, Netherlands) 2009 Sep;65(3):299-305
Lung cancer (Amsterdam, Netherlands) 2009 Sep;65(3):299-305
Activation of the WAVE complex by coincident signals controls actin assembly.
Lebensohn AM, Kirschner MW
Molecular cell 2009 Nov 13;36(3):512-24
Molecular cell 2009 Nov 13;36(3):512-24
Membrane transport of WAVE2 and lamellipodia formation require Pak1 that mediates phosphorylation and recruitment of stathmin/Op18 to Pak1-WAVE2-kinesin complex.
Takahashi K, Suzuki K
Cellular signalling 2009 May;21(5):695-703
Cellular signalling 2009 May;21(5):695-703
BetaPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport.
Morimura S, Suzuki K, Takahashi K
Biochemical and biophysical research communications 2009 May 8;382(3):614-9
Biochemical and biophysical research communications 2009 May 8;382(3):614-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC