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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17034-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17034-1-AP, RRID:AB_2147263
- Product name
- MUT antibody
- Antibody type
- Polyclonal
- Description
- MUT antibody (Cat. #17034-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references First-in-human nuclease-free homologous recombination-dependent gene editing in pediatric patients with methylmalonic acidemia: results of a phase 1/2 study.
Effects of anserine on oxidative stress and on cell barrier integrity in methylmalonic aciduria.
ACSS3 regulates the metabolic homeostasis of epithelial cells and alleviates pulmonary fibrosis.
Aging-Associated Metabolite Methylmalonic Acid Increases Susceptibility to Pulmonary Fibrosis.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia.
Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA.
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Bedoyan JK, Morgan T, Sun A, Li H, Gruskin D, Payton M, Chereau F, Swenson ES, Lin Q, Kay MA, Vockley J
Gene therapy 2026 Mar 30;
Gene therapy 2026 Mar 30;
Effects of anserine on oxidative stress and on cell barrier integrity in methylmalonic aciduria.
Köpfer F, Bartosova Medvid M, Fleming T, Pfeffer T, Okun JG, Kölker S, Hoffmann GF, Schmitt CP, Morath M, Peters V
Scientific reports 2025 Sep 25;15(1):32933
Scientific reports 2025 Sep 25;15(1):32933
ACSS3 regulates the metabolic homeostasis of epithelial cells and alleviates pulmonary fibrosis.
Wang L, Yuan H, Li W, Yan P, Zhao M, Li Z, Zhao H, Wang S, Wan R, Li Y, Yang J, Pan X, Rosas I, Yu G
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166960
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166960
Aging-Associated Metabolite Methylmalonic Acid Increases Susceptibility to Pulmonary Fibrosis.
Xu K, Ding L, Li W, Wang Y, Ma S, Lian H, Pan X, Wan R, Zhao W, Yang J, Rosas I, Wang L, Yu G
The American journal of pathology 2024 Aug;194(8):1478-1493
The American journal of pathology 2024 Aug;194(8):1478-1493
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia.
Zhang S, Bastille A, Gordo S, Ramesh N, Vora J, McCarthy E, Zhang X, Frank D, Ko CW, Wu C, Walsh N, Amarwani S, Liao J, Xiong Q, Drouin L, Hebben M, Chiang K, Chau BN
PloS one 2022;17(9):e0274774
PloS one 2022;17(9):e0274774
Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA.
Key J, Torres-Odio S, Bach NC, Gispert S, Koepf G, Reichlmeir M, West AP, Prokisch H, Freisinger P, Newman WG, Shalev S, Sieber SA, Wittig I, Auburger G
Cells 2021 Nov 29;10(12)
Cells 2021 Nov 29;10(12)
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Chandler RJ, Venturoni LE, Liao J, Hubbard BT, Schneller JL, Hoffmann V, Gordo S, Zang S, Ko CW, Chau N, Chiang K, Kay MA, Barzel A, Venditti CP
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237
Hepatology (Baltimore, Md.) 2021 Jun;73(6):2223-2237
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 17034-1-AP(MUT antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17034-1-AP(MUT antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MUT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MUT. This antibody recognizes human, mouse, rat antigen. The MUT antibody has been validated for the following applications: ELISA, WB, IHC analysis.
