BS8251

antibody from Bioworld Technology, Inc
Targeting: KIF2B
Provider product page for BS8251
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8251 - Provider product page
Provider
Bioworld Technology, Inc
Product name
KIF2B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human KIF2B.
Description
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF2B (kinesin family member 2B) is a 673 amino acid cytoplasmic protein that localizes to the kinetochore. Highly expressed in lung and ovary with moderate expression in heart, kidney, placenta skeletal muscle and spleen, KIF2B has microtubule depolymerization activity and is associated with peripheral translocation of lysosomes. Overexpression of KIF2B in cells result in abnormally large lysosome size and unusual positioning, which is some distance from their usual perinuclear location. KIF2B activity is critical for spindle assembly and chromosome movement.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KIF2B protein structure - BS8251 shown in red.