Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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Validation data
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- Product number
- H00003636-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00003636-M01, RRID:AB_2264866
- Product name
- Mouse Monoclonal SHIP2/INPPL1 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. INPPL1 - inositol polyphosphate phosphatase-like 1
- Reactivity
- Human, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Phosphoinositide 5-phosphatases SKIP and SHIP2 in ruffles, the endoplasmic reticulum and the nucleus: An update.
Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastoma.
The impact of phosphoinositide 5-phosphatases on phosphoinositides in cell function and human disease.
FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis.
SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells.
The SHIP2 interactor Myo1c is required for cell migration in 1321 N1 glioblastoma cells.
Phosphorylated SHIP2 on Y1135 localizes at focal adhesions and at the mitotic spindle in cancer cell lines.
SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts.
The host phosphoinositide 5-phosphatase SHIP2 regulates dissemination of vaccinia virus.
Ramos AR, Ghosh S, Suhel T, Chevalier C, Obeng EO, Fafilek B, Krejci P, Beck B, Erneux C
Advances in biological regulation 2020 Jan;75:100660
Advances in biological regulation 2020 Jan;75:100660
Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastoma.
Ramos AR, Ghosh S, Dedobbeleer M, Robe PA, Rogister B, Erneux C
The FEBS journal 2019 Mar;286(6):1120-1135
The FEBS journal 2019 Mar;286(6):1120-1135
The impact of phosphoinositide 5-phosphatases on phosphoinositides in cell function and human disease.
Ramos AR, Ghosh S, Erneux C
Journal of lipid research 2019 Feb;60(2):276-286
Journal of lipid research 2019 Feb;60(2):276-286
FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis.
Chan Wah Hak L, Khan S, Di Meglio I, Law AL, Lucken-Ardjomande Häsler S, Quintaneiro LM, Ferreira APA, Krause M, McMahon HT, Boucrot E
Nature cell biology 2018 Sep;20(9):1023-1031
Nature cell biology 2018 Sep;20(9):1023-1031
SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells.
Elong Edimo W, Ghosh S, Derua R, Janssens V, Waelkens E, Vanderwinden JM, Robe P, Erneux C
Journal of cell science 2016 Mar 15;129(6):1101-14
Journal of cell science 2016 Mar 15;129(6):1101-14
The SHIP2 interactor Myo1c is required for cell migration in 1321 N1 glioblastoma cells.
Edimo WE, Ramos AR, Ghosh S, Vanderwinden JM, Erneux C
Biochemical and biophysical research communications 2016 Aug 5;476(4):508-514
Biochemical and biophysical research communications 2016 Aug 5;476(4):508-514
Phosphorylated SHIP2 on Y1135 localizes at focal adhesions and at the mitotic spindle in cancer cell lines.
Deneubourg L, Elong Edimo W, Moreau C, Vanderwinden JM, Erneux C
Cellular signalling 2014 Jun;26(6):1193-203
Cellular signalling 2014 Jun;26(6):1193-203
SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts.
Elong Edimo W, Vanderwinden JM, Erneux C
Advances in biological regulation 2013 Jan;53(1):28-37
Advances in biological regulation 2013 Jan;53(1):28-37
The host phosphoinositide 5-phosphatase SHIP2 regulates dissemination of vaccinia virus.
McNulty S, Powell K, Erneux C, Kalman D
Journal of virology 2011 Jul;85(14):7402-10
Journal of virology 2011 Jul;85(14):7402-10
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SHIP2/INPPL1 Antibody (3E6) [H00003636-M01] - INPPL1 monoclonal antibody (M01), clone 3E6 Analysis of INPPL1 expression in HeLa.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: SHIP2/INPPL1 Antibody (3E6.) [H00003636-M01] - SHIP2/INPPL1 Antibody (3E6) [H00003636-M01] - Detection limit for recombinant GST tagged INPPL1 is approximately 0.1ng/ml as a capture antibody.