Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- 14259-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14259-1-AP, RRID:AB_2198222
- Product name
- Syntaxin 12 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Syntaxin 12 antibody (Cat. #14259-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner.
SLC34A2 promotes cell proliferation by activating STX17-mediated autophagy in esophageal squamous cell carcinoma.
Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.
Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.
Janusz-Kaminska A, Brzozowska A, Tempes A, Urbanska M, Blazejczyk M, Miłek J, Kuzniewska B, Zeng J, Wesławski J, Kisielewska K, Bassell GJ, Jaworski J
Molecular biology of the cell 2024 Mar 1;35(3):ar43
Molecular biology of the cell 2024 Mar 1;35(3):ar43
SLC34A2 promotes cell proliferation by activating STX17-mediated autophagy in esophageal squamous cell carcinoma.
Xu Y, Duan S, Ye W, Zheng Z, Zhang J, Gao Y, Ye S
Thoracic cancer 2024 Jun;15(17):1369-1384
Thoracic cancer 2024 Jun;15(17):1369-1384
Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.
Nůsková H, Cortizo FG, Schwenker LS, Sachsenheimer T, Diakonov EE, Tiebe M, Schneider M, Lohbeck J, Reid C, Kopp-Schneider A, Helm D, Brügger B, Miller AK, Teleman AA
The Journal of biological chemistry 2023 Sep;299(9):105088
The Journal of biological chemistry 2023 Sep;299(9):105088
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway.
Lv Y, Wang X, Li X, Xu G, Bai Y, Wu J, Piao Y, Shi Y, Xiang R, Wang L
PLoS biology 2020 Nov;18(11):e3000872
PLoS biology 2020 Nov;18(11):e3000872
Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.
Malik N, Nirujogi RS, Peltier J, Macartney T, Wightman M, Prescott AR, Gourlay R, Trost M, Alessi DR, Karapetsas A
The Biochemical journal 2019 Oct 30;476(20):3081-3107
The Biochemical journal 2019 Oct 30;476(20):3081-3107
Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.
Lu Y, Zhang Z, Sun D, Sweeney ST, Gao FB
Molecular cell 2013 Oct 24;52(2):264-71
Molecular cell 2013 Oct 24;52(2):264-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 14259-1-AP(STX12 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using STX12 antibody 14259-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 14259-1-AP(STX12 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 14259-1-AP(STX12 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Syntaxin 12 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Syntaxin 12. This antibody recognizes human,mouse,rat antigen. The Syntaxin 12 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.