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- Antigen structure
- References [10]
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- Western blot [1]
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- Product number
- 15743-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CLPB antibody
- Antibody type
- Polyclonal
- Description
- CLPB antibody (Cat. #15743-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Impact of PARL-mediated mitochondrial protease activity on calcium regulation.
Dependence of mitochondrial calcium signalling and dynamics on the disaggregase, CLPB.
Mitochondrial CLPB is a pro-survival factor at the onset of granulocytic differentiation of mouse myeloblastic cells.
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière's disease.
Exploring Potential Diagnostic Biomarkers for Mechanical Asphyxia in the Heart Based on Proteomics Technology.
Decreased apoptotic priming and loss of BCL-2 dependence are functional hallmarks of Richter's syndrome.
Dodecamer assembly of a metazoan AAA(+) chaperone couples substrate extraction to refolding.
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations.
Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region.
D'Angelo D, Al Saidi A, Ghirardo G, Vecellio Reane D, Gasparini N, Rizzuto R, Raffaello A
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):119998
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):119998
Dependence of mitochondrial calcium signalling and dynamics on the disaggregase, CLPB.
D'Angelo D, Sánchez-Vázquez VH, Cartes-Saavedra B, Vecellio Reane D, Cupo RR, Delgado de la Herran H, Ghirardo G, Shorter J, Wevers RA, Wortmann SB, Perocchi F, Rizzuto R, Raffaello A, Hajnóczky G
Nature communications 2025 Mar 21;16(1):2810
Nature communications 2025 Mar 21;16(1):2810
Mitochondrial CLPB is a pro-survival factor at the onset of granulocytic differentiation of mouse myeloblastic cells.
Wenta T, Wang G, Van Buren T, Zolkiewski M, Zolkiewska A
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):334-348
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):334-348
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière's disease.
Harhai M, Foged MM, Zarges C, Landoni JC, Chollet S, Simonelli M, Recazens E, Lisci M, Laban N, Manley S, Riemer J, Lopez-Escamez JA, Lysakowski A, Jourdain AA
Cell reports 2025 Aug 26;44(8):116069
Cell reports 2025 Aug 26;44(8):116069
Exploring Potential Diagnostic Biomarkers for Mechanical Asphyxia in the Heart Based on Proteomics Technology.
Huang Y, Qiu H, Chen Q, Meng Z, Qiao D, Yue X
International journal of molecular sciences 2024 Nov 26;25(23)
International journal of molecular sciences 2024 Nov 26;25(23)
Decreased apoptotic priming and loss of BCL-2 dependence are functional hallmarks of Richter's syndrome.
Rigo A, Vaisitti T, Laudanna C, Terrabuio E, Micillo M, Frusteri C, D'Ulivo B, Merigo F, Sbarbati A, Mellert K, Möeller P, Montresor A, Di Napoli A, Cirombella R, Butturini E, Massaia M, Constantin G, Vinante F, Deaglio S, Ferrarini I
Cell death & disease 2024 May 9;15(5):323
Cell death & disease 2024 May 9;15(5):323
Dodecamer assembly of a metazoan AAA(+) chaperone couples substrate extraction to refolding.
Gupta A, Lentzsch AM, Siegel A, Yu Z, Chio US, Cheng Y, Shan SO
Science advances 2023 May 10;9(19):eadf5336
Science advances 2023 May 10;9(19):eadf5336
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M
eLife 2023 Jul 28;12
eLife 2023 Jul 28;12
Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations.
Cupo RR, Shorter J
eLife 2020 Jun 23;9
eLife 2020 Jun 23;9
Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region.
Yoshinaka T, Kosako H, Yoshizumi T, Furukawa R, Hirano Y, Kuge O, Tamada T, Koshiba T
iScience 2019 Sep 27;19:1065-1078
iScience 2019 Sep 27;19:1065-1078
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 15743-1-AP( CLPB Antibody) at dilution of 1:700
- Other comments
- WB
