PAB3084

antibody from Abnova Corporation

Targeting: FRAT1

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB3084

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB3084, RRID:AB_1574967

Product name

FRAT1 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of FRAT1.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A.

Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD
The Journal of biological chemistry 2006 Nov 17;281(46):35021-9

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Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours.

Wang Y, Hewitt SM, Liu S, Zhou X, Zhu H, Zhou C, Zhang G, Quan L, Bai J, Xu N
British journal of cancer 2006 Mar 13;94(5):686-91

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Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin.

Hino S, Michiue T, Asashima M, Kikuchi A
The Journal of biological chemistry 2003 Apr 18;278(16):14066-73

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of FRAT1 (arrow) using rabbit FRAT1 polyclonal antibody (Cat # PAB3084). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FRAT1 gene (Lane 2) (Origene Technologies).