Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2847218 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1) (AA 244-274), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 244-274, C-Term
- Antibody clone number
- RB14254
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references The clinical significance of FRAT1 and ABCG2 expression in pancreatic ductal adenocarcinoma.
FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A.
Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours.
Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin.
Yuan Y, Yang Z, Miao X, Li D, Liu Z, Zou Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Dec;36(12):9961-8
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Dec;36(12):9961-8
FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A.
Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD
The Journal of biological chemistry 2006 Nov 17;281(46):35021-9
The Journal of biological chemistry 2006 Nov 17;281(46):35021-9
Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours.
Wang Y, Hewitt SM, Liu S, Zhou X, Zhu H, Zhou C, Zhang G, Quan L, Bai J, Xu N
British journal of cancer 2006 Mar 13;94(5):686-91
British journal of cancer 2006 Mar 13;94(5):686-91
Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin.
Hino S, Michiue T, Asashima M, Kikuchi A
The Journal of biological chemistry 2003 Apr 18;278(16):14066-73
The Journal of biological chemistry 2003 Apr 18;278(16):14066-73
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC