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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Immunohistochemistry [1]
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- Product number
- 24091-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SPRED2 antibody
- Antibody type
- Polyclonal
- Description
- SPRED2 antibody (Cat. #24091-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neurofibromin Encoded by the Neurofibromatosis Type 1 (NF1) Gene Promotes the Membrane Translocation of SPRED2, Thereby Inhibiting the ERK Pathway in Breast Cancer Cells.
Expression of SPRED2 in the lung adenocarcinoma.
SPRED2 Is a Novel Regulator of Autophagy in Hepatocellular Carcinoma Cells and Normal Hepatocytes.
microRNA-141-3p mediates epithelial cell proliferation, apoptosis, and epithelial-mesenchymal transition and alleviates pulmonary fibrosis in mice via Spred2.
SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells.
Inhibition of Spred/Sprouty Expression in the Skin of a Contact Dermatitis-Like Model.
Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder.
Su Pwint NT, Li C, Gao T, Wang Y, Fujisawa M, Ohara T, Sakaguchi M, Yoshimura T, Matsukawa A
International journal of molecular sciences 2025 Oct 16;26(20)
International journal of molecular sciences 2025 Oct 16;26(20)
Expression of SPRED2 in the lung adenocarcinoma.
Ota Y, Gao T, Fujisawa M, Sumardika IW, Sakaguchi M, Toyooka S, Yoshimura T, Matsukawa A
Pathology, research and practice 2025 Jan;265:155721
Pathology, research and practice 2025 Jan;265:155721
SPRED2 Is a Novel Regulator of Autophagy in Hepatocellular Carcinoma Cells and Normal Hepatocytes.
Wang T, Gao T, Fujisawa M, Ohara T, Sakaguchi M, Yoshimura T, Matsukawa A
International journal of molecular sciences 2024 Jun 6;25(11)
International journal of molecular sciences 2024 Jun 6;25(11)
microRNA-141-3p mediates epithelial cell proliferation, apoptosis, and epithelial-mesenchymal transition and alleviates pulmonary fibrosis in mice via Spred2.
Zhu L, Chen M, Wang W, Zhu J, Wu H
Histology and histopathology 2023 Nov;38(11):1269-1282
Histology and histopathology 2023 Nov;38(11):1269-1282
SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells.
Gao T, Yang X, Fujisawa M, Ohara T, Wang T, Tomonobu N, Sakaguchi M, Yoshimura T, Matsukawa A
International journal of molecular sciences 2023 Mar 5;24(5)
International journal of molecular sciences 2023 Mar 5;24(5)
Inhibition of Spred/Sprouty Expression in the Skin of a Contact Dermatitis-Like Model.
Sakai H, Sato K, Ito K, Kosugi I, Kiyama M, Kon R, Ikarashi N, Kamei J, Chiba Y, Hosoe T
Biological & pharmaceutical bulletin 2022;45(8):1208-1212
Biological & pharmaceutical bulletin 2022;45(8):1208-1212
Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder.
Oda S, Fujisawa M, Chunning L, Ito T, Yamaguchi T, Yoshimura T, Matsukawa A
PloS one 2021;16(11):e0254289
PloS one 2021;16(11):e0254289
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SPRED2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SPRED2. This antibody recognizes human, mouse, rat antigen. The SPRED2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
