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- References [24]
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- Immunohistochemistry [2]
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- Product number
- 16126-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16126-1-AP, RRID:AB_2160786
- Product name
- PGAM1 antibody
- Antibody type
- Polyclonal
- Description
- PGAM1 antibody (Cat. #16126-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pan-Cancer Analysis of PGAM1 and Its Experimental Validation in Uveal Melanoma Progression.
ELP3 stabilizes c-Myc to promote tumorigenesis.
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity.
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
Ubiquitin specific protease 46 potentiates triple negative breast cancer development by stabilizing PGAM1-mediated glycolysis.
RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation via TRIM32.
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Development of a Novel Circulating Autoantibody Biomarker Panel for the Identification of Patients with 'Actionable' Pulmonary Nodules.
Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.
Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells.
A Schistosoma japonicum MicroRNA Exerts Antitumor Effects Through Inhibition of Both Cell Migration and Angiogenesis by Targeting PGAM1.
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Niu W, Yang Y, Teng Y, Zhang N, Li X, Qin Y
Journal of Cancer 2024;15(7):2074-2094
Journal of Cancer 2024;15(7):2074-2094
ELP3 stabilizes c-Myc to promote tumorigenesis.
Zhao W, Ouyang C, Huang C, Zhang J, Xiao Q, Zhang F, Wang H, Lin F, Wang J, Wang Z, Jiang B, Li Q
Journal of molecular cell biology 2024 Apr 4;15(9)
Journal of molecular cell biology 2024 Apr 4;15(9)
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity.
Sun X, He L, Liu H, Thorne RF, Zeng T, Liu L, Zhang B, He M, Huang Y, Li M, Gao E, Ma M, Cheng C, Meng F, Lang C, Li H, Xiong W, Pan S, Ren D, Dang B, Yang Y, Wu M, Liu L
Cell metabolism 2023 Sep 5;35(9):1563-1579.e8
Cell metabolism 2023 Sep 5;35(9):1563-1579.e8
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Wu YQ, Zhang CS, Xiong J, Cai DQ, Wang CZ, Wang Y, Liu YH, Wang Y, Li Y, Wu J, Wu J, Lan B, Wang X, Chen S, Cao X, Wei X, Hu HH, Guo H, Yu Y, Ghafoor A, Xie C, Wu Y, Xu Z, Zhang C, Zhu M, Huang X, Sun X, Lin SY, Piao HL, Zhou J, Lin SC
Cell research 2023 Nov;33(11):835-850
Cell research 2023 Nov;33(11):835-850
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
Tan J, Wang W, Liu X, Xu J, Che Y, Liu Y, Hu J, Hu L, Li J, Zhou Q
Communications biology 2023 Jun 5;6(1):606
Communications biology 2023 Jun 5;6(1):606
Ubiquitin specific protease 46 potentiates triple negative breast cancer development by stabilizing PGAM1-mediated glycolysis.
Ke L, Jia Z, Gao W, Luo L
Cell biology international 2023 Jan;47(1):41-51
Cell biology international 2023 Jan;47(1):41-51
RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation via TRIM32.
Wang L, Song YY, Wang Y, Liu XX, Yin YL, Gao S, Zhang F, Li LY, Zhang ZS
Pharmacological research 2023 Dec;198:106995
Pharmacological research 2023 Dec;198:106995
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Luo JQ, Yang TW, Wu J, Lai HH, Zou LB, Chen WB, Zhou XM, Lv DJ, Cen SR, Long ZN, Mao YY, Zheng PX, Su XH, Xian ZY, Shu FP, Mao XM
Cell death & disease 2023 Aug 4;14(8):502
Cell death & disease 2023 Aug 4;14(8):502
Development of a Novel Circulating Autoantibody Biomarker Panel for the Identification of Patients with 'Actionable' Pulmonary Nodules.
Auger C, Moudgalya H, Neely MR, Stephan JT, Tarhoni I, Gerard D, Basu S, Fhied CL, Abdelkader A, Vargas M, Hu S, Hulett T, Liptay MJ, Shah P, Seder CW, Borgia JA
Cancers 2023 Apr 12;15(8)
Cancers 2023 Apr 12;15(8)
Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.
Zhang X, Luo F, Luo S, Li L, Ren X, Lin J, Liang Y, Ma C, Ding L, Zhang D, Ye T, Lin Y, Jin B, Gao S, Ye Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(27):e2200705
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(27):e2200705
Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
Santos MN, Paushter DH, Zhang T, Wu X, Feng T, Lou J, Du H, Becker SM, Fragoza R, Yu H, Hu F
The Journal of biological chemistry 2022 Sep;298(9):102348
The Journal of biological chemistry 2022 Sep;298(9):102348
MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.
Liu M, Du Q, Mao G, Dai N, Zhang F
Bioengineered 2022 Mar;13(3):5344-5356
Bioengineered 2022 Mar;13(3):5344-5356
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
Zhu Y, Jin L, Shi R, Li J, Wang Y, Zhang L, Liang CZ, Narayana VK, De Souza DP, Thorne RF, Zhang LR, Zhang XD, Wu M
Molecular cell 2022 Feb 3;82(3):542-554.e6
Molecular cell 2022 Feb 3;82(3):542-554.e6
U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells.
Li Y, Chen S, Zhang X, Zhuo N
Bioengineered 2022 Apr;13(4):10200-10212
Bioengineered 2022 Apr;13(4):10200-10212
A Schistosoma japonicum MicroRNA Exerts Antitumor Effects Through Inhibition of Both Cell Migration and Angiogenesis by Targeting PGAM1.
Hu C, Li Y, Pan D, Wang J, Zhu L, Lin Y, Zhu S, Pan W
Frontiers in oncology 2021;11:652395
Frontiers in oncology 2021;11:652395
Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness.
Li R, Li H, Zhu L, Zhang X, Liu D, Li Q, Ni B, Hu L, Zhang Z, Zhang Y, Wang X, Jiang SH
Cell death & disease 2021 Nov 26;12(12):1106
Cell death & disease 2021 Nov 26;12(12):1106
Valproic acid Suppresses Breast Cancer Cell Growth Through Triggering Pyruvate Kinase M2 Isoform Mediated Warburg Effect.
Li Z, Yang L, Zhang S, Song J, Sun H, Shan C, Wang D, Liu S
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Cell transplantation 2021 Jan-Dec;30:9636897211027524
Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.
Yang G, Yuan Y, Yuan H, Wang J, Yun H, Geng Y, Zhao M, Li L, Weng Y, Liu Z, Feng J, Bu Y, Liu L, Wang B, Zhang X
EMBO reports 2021 Feb 3;22(2):e50967
EMBO reports 2021 Feb 3;22(2):e50967
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, Dhamdhere M, Zheng N, Shah T, Shah A, Axelrad JB, Anvar NE, Lin YH, Jiang S, Chang EQ, Ingram DR, Wang WL, Lazar A, Lee MG, Muller F, Wang L, Ying H, Rai K
Cell reports 2020 Oct 20;33(3):108293
Cell reports 2020 Oct 20;33(3):108293
Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect.
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, Wang Y, Shen C, Liu Y, Wang T, Han J, Zhao C
Cancer science 2020 Jun;111(6):2028-2040
Cancer science 2020 Jun;111(6):2028-2040
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cancer cell 2018 Mar 12;33(3):368-385.e7
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, Wang J, Liu Z, Zhong X, He X, Shen S, Pan X, Li A, Wang Y, Gao P, Tang H, Zhang H
Cell research 2015 Apr;25(4):429-44
Cell research 2015 Apr;25(4):429-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 16126-1-AP(PGAM1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16126-1-AP(PGAM1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PGAM1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PGAM1. This antibody recognizes human,mouse,rat antigen. The PGAM1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
