GRIK5

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Description

glutamate ionotropic receptor kainate type subunit 5

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

19:q13.2 (41998321 - 42069498)

Ensembl ID

ENSG00000105737  (ver. 99.38)

Orthologs

Mouse Grik5: ENSMUSG00000003378

UniProt

Q16478

neXtProt

NX_Q16478

Human splice variants
Mouse splice variants