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- Antibody Data
- Antigen structure
- References [7]
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- Product number
- 16552-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SMPDL3B antibody
- Antibody type
- Polyclonal
- Description
- SMPDL3B antibody (Cat. #16552-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation.
SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis.
SMPDL3B contributes to gastric adenocarcinoma cells progression by promoting the infiltration of M2 macrophages.
Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism.
SMPDL3B Predicts Poor Prognosis and Contributes to Development of Acute Myeloid Leukemia.
Macrophage-derived thrombospondin 1 promotes obesity-associated non-alcoholic fatty liver disease.
Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats.
Wang Z, Hou Y, Liu P, Wu R, Yang J, Fan S, Peng Z, Han X, Su B, Zhang C
Immunity 2025 Nov 11;58(11):2670-2684.e10
Immunity 2025 Nov 11;58(11):2670-2684.e10
SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis.
Rostami-Afshari B, Elremaly W, Franco A, Elbakry M, Akoume MY, Boufaied I, Moezzi A, Leveau C, Rompré P, Godbout C, Mella O, Fluge Ø, Moreau A
Journal of translational medicine 2025 Jul 7;23(1):748
Journal of translational medicine 2025 Jul 7;23(1):748
SMPDL3B contributes to gastric adenocarcinoma cells progression by promoting the infiltration of M2 macrophages.
Su L, Hao J, Zhang N, Wu S, Wu X, Wei W
Turkish journal of medical sciences 2023;53(6):1635-1647
Turkish journal of medical sciences 2023;53(6):1635-1647
Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism.
Shen HH, Zhao Q, Wen YP, Wu R, Du SY, Huang XB, Wen XT, Cao SJ, Zeng L, Yan QG
iScience 2023 Aug 18;26(8):107450
iScience 2023 Aug 18;26(8):107450
SMPDL3B Predicts Poor Prognosis and Contributes to Development of Acute Myeloid Leukemia.
Qu H, Zhu Y
Frontiers in molecular biosciences 2021;8:695601
Frontiers in molecular biosciences 2021;8:695601
Macrophage-derived thrombospondin 1 promotes obesity-associated non-alcoholic fatty liver disease.
Gwag T, Reddy Mooli RG, Li D, Lee S, Lee EY, Wang S
JHEP reports : innovation in hepatology 2021 Feb;3(1):100193
JHEP reports : innovation in hepatology 2021 Feb;3(1):100193
Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats.
Li X, Jin SJ, Su J, Li XX, Xu M
Basic & clinical pharmacology & toxicology 2018 Dec;123(6):645-659
Basic & clinical pharmacology & toxicology 2018 Dec;123(6):645-659
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