BS8257

antibody from Bioworld Technology, Inc
Targeting: IL17F IL-17F, ML-1, ML1
Provider product page for BS8257
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8257 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IL17F polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IL17F.
Description
The proinflammatory cytokine Interleukin 17 (IL-17) is produced by activated T cells to elicit potent cellular responses. IL-17 is secreted as a disulfide-linked homodimeric glycoprotein. A human IL-17 homolog IL-17E is a ligand for EV127/IL-17BR, which is also known as IL-17 receptor homolog 1. IL-17E mRNA is detected at very low levels in several peripheral tissues. IL-17E induces the activation of NF°ÙB and stimulates the production of the proinflammatory chemokine IL-8. In addition, IL-17E has catabolic activity on human articular cartilage. IL-17E is a unique pleiotropic cytokine that may be an important mediator of inflammatory and immune responses. Another homolog of IL-17, IL-17F, is a secreted cytokine expressed only in activated CD4+ T cells and activated monocytes. IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and regulates cartilage matrix turnover.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL17F protein structure - BS8257 shown in red.