ABIN372657

antibody from antibodies-online

Targeting: GLRA1 STHE

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN372657

Provider

antibodies-online

Product name

anti-Glycine Receptor, alpha 1 (GLRA1) (N-Term) antibody

Antibody type

Polyclonal

Antigen

Peptide from the N-terminus region of the alpha-1 subunit of rat Glycine Receptor.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.2 mg

Storage

After reconstitution: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

References

Submitted references

A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor.

Schofield CM, Jenkins A, Harrison NL
The Journal of biological chemistry 2003 Sep 5;278(36):34079-83

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Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits.

Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Cui J, Tu S, Sevarino KA, Nakanishi N, Tong G, Lipton SA, Zhang D
Nature 2002 Feb 14;415(6873):793-8

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Getting a bead on receptor movements.

Craig AM, Lichtman JW
Nature neuroscience 2001 Mar;4(3):219-20

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Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor function.

Beckstead MJ, Phelan R, Mihic SJ
The Journal of biological chemistry 2001 Jul 6;276(27):24959-64

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Reduced synaptic clustering of GABA and glycine receptors in the retina of the gephyrin null mutant mouse.

Fischer F, Kneussel M, Tintrup H, Haverkamp S, Rauen T, Betz H, Wässle H
The Journal of comparative neurology 2000 Nov 27;427(4):634-48

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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL
Nature 1997 Sep 25;389(6649):385-9