Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8224 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- C1D polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human C1D.
- Description
- C1D, also known as SUNCOR, is a nuclear DNA-binding protein that localizes to the nucleus and cytoplasm and participates in processing of the 5.8S rRNA. Expressed ubiquitously with highest expression in thyroid, salivary gland, hippocampus and medulla oblongata, C1D forms a multi-protein complex with MPP6 (M phase phosphoprotein 6) and EXOSC10 (exosome component 10). This complex is responsible, in part, for recruiting the exosome to pre-rRNA and it functions to mediate 3£ª-5£ª rRNA processing. Additionally, C1D can induce transcriptional repression and apoptosis through interaction with Rev-erbÏ« (V-erbA-related protein EAR-1)/TRÉÇ (thyroid hormone receptor ÉÇ) and p53, respectively. C1D, a 141 amino acid protein, is also implicated in DNA repair mechanisms, as well as DNA-PK (DNA-dependent protein kinase) activation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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