BS8224

antibody from Bioworld Technology, Inc
Targeting: C1D LRP1, Rrp47, SUN-CoR, SUNCOR
Provider product page for BS8224
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8224 - Provider product page
Provider
Bioworld Technology, Inc
Product name
C1D polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human C1D.
Description
C1D, also known as SUNCOR, is a nuclear DNA-binding protein that localizes to the nucleus and cytoplasm and participates in processing of the 5.8S rRNA. Expressed ubiquitously with highest expression in thyroid, salivary gland, hippocampus and medulla oblongata, C1D forms a multi-protein complex with MPP6 (M phase phosphoprotein 6) and EXOSC10 (exosome component 10). This complex is responsible, in part, for recruiting the exosome to pre-rRNA and it functions to mediate 3£ª-5£ª rRNA processing. Additionally, C1D can induce transcriptional repression and apoptosis through interaction with Rev-erbÏ« (V-erbA-related protein EAR-1)/TRÉÇ (thyroid hormone receptor ÉÇ) and p53, respectively. C1D, a 141 amino acid protein, is also implicated in DNA repair mechanisms, as well as DNA-PK (DNA-dependent protein kinase) activation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
C1D protein structure - BS8224 shown in red.