Tissue expression
Cell line expression
Protein structure

PTAFR

Platelet activating factor receptor
 
This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
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239 antibodies from 26 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
69 antibodies
Biorbyt
63 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
12 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abnova Corporation
3 antibodies
FineTest Biotech
1 antibody
St John's Laboratory
1 antibody
Aviva Systems Biology
3 antibodies
Novus Biologicals
3 antibodies
Atlas Antibodies
1 antibody
OriGene
1 antibody
Abbexa
6 antibodies
Creative Diagnostics
3 antibodies
GeneTex
2 antibodies
Abiocode, Inc.
1 antibody
MyBioSource
3 antibodies
Creative Biolabs
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
United States Biological
13 antibodies
Leading Biology
1 antibody
MilliporeSigma / Merck KGaA
1 antibody
ProSci
1 antibody