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- Antibody Data
- Antigen structure
- References [3]
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- Western blot [1]
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- Product number
- AMAb91189 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#AMAb91189, RRID:AB_2665837
- Product name
- Anti-MCU
- Antibody type
- Monoclonal
- Description
- Monoclonal Antibody against Human MCU, Clone ID: CL3576, Gene description: mitochondrial calcium uniporter, Alternative Gene Names: C10orf42, CCDC109A, FLJ46135, Validated applications: ICC, WB, Uniprot ID: Q8NE86, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- CL3576
- Vial size
- 100 µl
- Concentration
- 1.0 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Monitoring mitochondrial calcium in cardiomyocytes during coverslip hypoxia using a fluorescent lifetime indicator
Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosis
Excessive Accumulation of Ca2 + in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State
Mastoor Y, Harata M, Silva K, Liu C, Combs C, Roman B, Murphy E
Journal of Molecular and Cellular Cardiology Plus 2024;8
Journal of Molecular and Cellular Cardiology Plus 2024;8
Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosis
Gu L, Larson Casey J, Andrabi S, Lee J, Meza-Perez S, Randall T, Carter A
Redox Biology 2019;26
Redox Biology 2019;26
Excessive Accumulation of Ca2 + in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State
Canato M, Capitanio P, Cancellara L, Leanza L, Raffaello A, Reane D, Marcucci L, Michelucci A, Protasi F, Reggiani C
Frontiers in Physiology 2019;10
Frontiers in Physiology 2019;10
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in A-549 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-MCU antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
