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- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11975-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11975-1-AP, RRID:AB_2101786
- Product name
- FANCA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FANCA antibody (Cat. #11975-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FANCA promotes lung adenocarcinoma progression and is a potential target for epitope vaccine immunotherapy.
Circular RNA Circ_0000119 promotes gastric cancer progression via circ_0000119/miR-502-5p/MTBP axis.
Acetylation-dependent regulation of core spliceosome modulates hepatocellular carcinoma cassette exons and sensitivity to PARP inhibitors.
FANCA facilitates G1/S cell cycle advancement, proliferation, migration and invasion in gastric cancer.
C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair.
Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress.
WNT inhibition creates a BRCA-like state in Wnt-addicted cancer.
Identification of rare heterozygous missense mutations in FANCA in esophageal atresia patients using next-generation sequencing.
Kang Y, Zhong R, Gan Y, You J, Chen J, Chen F, Chen L
Journal of translational medicine 2024 Oct 7;22(1):911
Journal of translational medicine 2024 Oct 7;22(1):911
Circular RNA Circ_0000119 promotes gastric cancer progression via circ_0000119/miR-502-5p/MTBP axis.
Xie M, Gu Y, Xu T, Jing X, Shu Y
Gene 2024 May 25;908:148296
Gene 2024 May 25;908:148296
Acetylation-dependent regulation of core spliceosome modulates hepatocellular carcinoma cassette exons and sensitivity to PARP inhibitors.
Sun L, Liu Y, Guo X, Cui T, Wu C, Tao J, Cheng C, Chu Q, Ji C, Li X, Guo H, Liang S, Zhou H, Zhou S, Ma K, Zhang N, Wang J, Liu Y, Liu L
Nature communications 2024 Jun 18;15(1):5209
Nature communications 2024 Jun 18;15(1):5209
FANCA facilitates G1/S cell cycle advancement, proliferation, migration and invasion in gastric cancer.
Wang W, Baral S, Liu B, Sun Q, Wang L, Ren J, Tang D, Wang D
Acta biochimica et biophysica Sinica 2024 Apr 29;56(7):973-985
Acta biochimica et biophysica Sinica 2024 Apr 29;56(7):973-985
C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair.
Zhou Z, Yang H, Liang X, Zhou T, Zhang T, Yang Y, Wang J, Wang W
Cell reports 2023 Aug 29;42(8):112907
Cell reports 2023 Aug 29;42(8):112907
Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress.
Xu X, Xu Y, Guo R, Xu R, Fu C, Xing M, Sasanuma H, Li Q, Takata M, Takeda S, Guo R, Xu D
Nature structural & molecular biology 2021 Jun;28(6):487-500
Nature structural & molecular biology 2021 Jun;28(6):487-500
WNT inhibition creates a BRCA-like state in Wnt-addicted cancer.
Kaur A, Lim JYS, Sepramaniam S, Patnaik S, Harmston N, Lee MA, Petretto E, Virshup DM, Madan B
EMBO molecular medicine 2021 Apr 9;13(4):e13349
EMBO molecular medicine 2021 Apr 9;13(4):e13349
Identification of rare heterozygous missense mutations in FANCA in esophageal atresia patients using next-generation sequencing.
Feng Y, Chen R, Da M, Qian B, Mo X
Gene 2018 Jun 30;661:182-188
Gene 2018 Jun 30;661:182-188
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11975-1-AP(FANCA antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FANCA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FANCA. This antibody recognizes human antigen. The FANCA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
