Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14475-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14475-1-AP, RRID:AB_2232810
- Product name
- GSTA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GSTA1 antibody (Cat. #14475-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis.
Protein Signatures for Distinguishing Colorectal Cancer Liver Metastases from Primary Liver Cancer Using Tissue Slide Proteomics.
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function.
Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cells.
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice.
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.
Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.
Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.
Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.
von Mässenhausen A, Schlecht MN, Beer K, Maremonti F, Tonnus W, Belavgeni A, Gavali S, Flade K, Riley JS, Zamora Gonzalez N, Brucker A, Becker JN, Tmava M, Meyer C, Peitzsch M, Hugo C, Gembardt F, Angeli JPF, Bornstein SR, Tait SWG, Linkermann A
Science advances 2024 Mar 15;10(11):eadk7329
Science advances 2024 Mar 15;10(11):eadk7329
Protein Signatures for Distinguishing Colorectal Cancer Liver Metastases from Primary Liver Cancer Using Tissue Slide Proteomics.
Zhou X, Wang X, Bai R, Li H, Hua D, Gao XD, Yang G, Liu Q
Frontiers in bioscience (Landmark edition) 2024 Jan 9;29(1):3
Frontiers in bioscience (Landmark edition) 2024 Jan 9;29(1):3
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function.
Wu K, Yan M, Liu T, Wang Z, Duan Y, Xia Y, Ji G, Shen Y, Wang L, Li L, Zheng P, Dong B, Wu Q, Xiao L, Yang X, Shen H, Wen T, Zhang J, Yi J, Deng Y, Qian X, Ma L, Fang J, Zhou Q, Lu Z, Xu D
Nature cell biology 2023 May;25(5):714-725
Nature cell biology 2023 May;25(5):714-725
Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Fan S, Yan Y, Xia Y, Zhou Z, Luo L, Zhu M, Han Y, Yao D, Zhang L, Fang M, Peng L, Yu J, Liu Y, Gao X, Guan H, Li H, Wang C, Wu X, Zhu H, Cao Y, Huang C
Nature communications 2023 Jun 8;14(1):3368
Nature communications 2023 Jun 8;14(1):3368
Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.
Dahlke E, Engmann T, Anan Y, Häsler R, Solinas G, Theilig F
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cells.
Ito Y, Oshinden K, Kutsuzawa N, Kohno C, Isaki S, Yokoyama K, Sato T, Tanaka M, Asano K
PloS one 2020;15(11):e0242789
PloS one 2020;15(11):e0242789
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Wang Z, Cai L, Li H, Liang M, Zhang Y, Wu Q, Yang L
Journal of food biochemistry 2020 May;44(5):e13180
Journal of food biochemistry 2020 May;44(5):e13180
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574
Journal of medicinal food 2020 Jun;23(6):565-574
γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice.
Rungratanawanich W, Cenini G, Mastinu A, Sylvester M, Wilkening A, Abate G, Bonini SA, Aria F, Marziano M, Maccarinelli G, Memo M, Voos W, Uberti D
Nutrients 2019 Mar 31;11(4)
Nutrients 2019 Mar 31;11(4)
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Wang Z, Liang M, Li H, Cai L, He H, Wu Q, Yang L
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862
l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.
Liang M, Wang Z, Li H, Cai L, Pan J, He H, Wu Q, Tang Y, Ma J, Yang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328
Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.
Wang C, Xu W, Zhang Y, Huang D, Huang K
Cell death & disease 2018 Jul 26;9(8):819
Cell death & disease 2018 Jul 26;9(8):819
Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.
Rojanathammanee L, Rakoczy S, Kopchick J, Brown-Borg HM
Age (Dordrecht, Netherlands) 2014;36(4):9687
Age (Dordrecht, Netherlands) 2014;36(4):9687
Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.
Rojanathammanee L, Rakoczy S, Brown-Borg HM
The journals of gerontology. Series A, Biological sciences and medical sciences 2014 Oct;69(10):1199-211
The journals of gerontology. Series A, Biological sciences and medical sciences 2014 Oct;69(10):1199-211
Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.
Shirai M, Arakawa S, Miida H, Matsuyama T, Kinoshita J, Makino T, Kai K, Teranishi M
Journal of toxicologic pathology 2013 Jun;26(2):175-86
Journal of toxicologic pathology 2013 Jun;26(2):175-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 14475-1-AP(GSTA1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using GSTA1 antibody 14475-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14475-1-AP(GSTA1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 14475-1-AP(GSTA1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue