14475-1-AP

antibody from Proteintech Group

Targeting: GSTA1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

14475-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#14475-1-AP, RRID:AB_2232810

Product name

GSTA1 antibody

Antibody type

Polyclonal

Description

KD/KO validated GSTA1 antibody (Cat. #14475-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

GSTA1 deficiency drives neuroendocrine differentiation via TNFRSF13B/c-FOS/CHGA axis in prostate cancer.

Qian J, Luo Y, Fu Y, Diao W, Ding Q, Chen W, Qiu X, Guo H
International journal of biological sciences 2026;22(3):1632-1647

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Integrated analysis reveals GSTA1 as a prognostic biomarker in stage I lung adenocarcinoma.

Ren J, Zeng H, Zhang G, Ren F, Yuan Z, Huang Y, Xu J, Song Z, Li W, Ying J, Xue Q, Tan F
BMC cancer 2026 Feb 10;26(1)

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Testosterone-mediated regulation of renal GSTA1/2 expression in male mice.

Hwang H, Park Y, Jeon SY, Ryu DY
Journal of veterinary science 2025 Sep;26(5):e74

---

Lysosome stress response and mitochondria injury are the earliest detectable alteration in FSGS.

Dahlke E, Promnitz J, Miranda MT, Saudenova M, Mollet G, Theilig F
Scientific reports 2025 Oct 13;15(1):35570

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Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.

Ding X, Han X, Zhang Y, Zhang Y, Li F, Wang J
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565

---

Targeting farnesoid X receptor as aging intervention therapy.

Zhang L, Yu J, Gao X, Yan Y, Wang X, Shi H, Fang M, Liu Y, Kim YB, Zhu H, Wu X, Huang C, Fan S
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1359-1382

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CBX3 promotes multidrug resistance by suppressing ferroptosis in colorectal carcinoma via the CUL3/NRF2/GPX2 axis.

Bai X, Duan T, Shao J, Zhang Y, Xing G, Wang J, Liu X, Wang M, He Y, Wang H, Zhang ZY, Ni M, Zhou JY, Pan J
Oncogene 2025 Jun;44(22):1678-1693

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Loss of Urat1 exacerbates APAP-induced liver injury in mice.

Zhao K, Zhang S, Tian J, Wu S, Chen Y, Wu Z, Liang J, Wu H, Pang J, Wu T
Toxicology 2025 Feb;511:154070

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4-Octyl Itaconate Attenuates Cell Proliferation by Cellular Senescence via Glutathione Metabolism Disorders and Mitochondrial Dysfunction in Melanoma.

Hayashi Y, Saeki A, Yoshimoto S, Yano E, Yasukochi A, Kimura S, Utsunomiya T, Minami K, Aso Y, Hatakeyama Y, Lo YC, Hirata M, Jimi E, Kawakubo-Yasukochi T
Antioxidants & redox signaling 2025 Apr;42(10-12):547-565

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Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis.

von Mässenhausen A, Schlecht MN, Beer K, Maremonti F, Tonnus W, Belavgeni A, Gavali S, Flade K, Riley JS, Zamora Gonzalez N, Brucker A, Becker JN, Tmava M, Meyer C, Peitzsch M, Hugo C, Gembardt F, Angeli JPF, Bornstein SR, Tait SWG, Linkermann A
Science advances 2024 Mar 15;10(11):eadk7329

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Investigation of ferroptosis-associated molecular subtypes and immunological characteristics in lupus nephritis based on artificial neural network learning.

Zhang L, Yan Q, Lin M, He J, Tian J, Chen Z, Hong F
Arthritis research & therapy 2024 Jul 3;26(1):126

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Protein Signatures for Distinguishing Colorectal Cancer Liver Metastases from Primary Liver Cancer Using Tissue Slide Proteomics.

Zhou X, Wang X, Bai R, Li H, Hua D, Gao XD, Yang G, Liu Q
Frontiers in bioscience (Landmark edition) 2024 Jan 9;29(1):3

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Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function.

Wu K, Yan M, Liu T, Wang Z, Duan Y, Xia Y, Ji G, Shen Y, Wang L, Li L, Zheng P, Dong B, Wu Q, Xiao L, Yang X, Shen H, Wen T, Zhang J, Yi J, Deng Y, Qian X, Ma L, Fang J, Zhou Q, Lu Z, Xu D
Nature cell biology 2023 May;25(5):714-725

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Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.

Fan S, Yan Y, Xia Y, Zhou Z, Luo L, Zhu M, Han Y, Yao D, Zhang L, Fang M, Peng L, Yu J, Liu Y, Gao X, Guan H, Li H, Wang C, Wu X, Zhu H, Cao Y, Huang C
Nature communications 2023 Jun 8;14(1):3368

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Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

Dahlke E, Engmann T, Anan Y, Häsler R, Solinas G, Theilig F
International journal of molecular sciences 2022 Sep 5;23(17)

---

L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.

Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744

---

Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.

Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838

---

Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cells.

Ito Y, Oshinden K, Kutsuzawa N, Kohno C, Isaki S, Yokoyama K, Sato T, Tanaka M, Asano K
PloS one 2020;15(11):e0242789

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Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.

Wang Z, Cai L, Li H, Liang M, Zhang Y, Wu Q, Yang L
Journal of food biochemistry 2020 May;44(5):e13180

---

Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.

Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574

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γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice.

Rungratanawanich W, Cenini G, Mastinu A, Sylvester M, Wilkening A, Abate G, Bonini SA, Aria F, Marziano M, Maccarinelli G, Memo M, Voos W, Uberti D
Nutrients 2019 Mar 31;11(4)

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l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.

Wang Z, Liang M, Li H, Cai L, He H, Wu Q, Yang L
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862

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l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.

Liang M, Wang Z, Li H, Cai L, Pan J, He H, Wu Q, Tang Y, Ma J, Yang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328

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Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.

Wang C, Xu W, Zhang Y, Huang D, Huang K
Cell death & disease 2018 Jul 26;9(8):819

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Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Rojanathammanee L, Rakoczy S, Kopchick J, Brown-Borg HM
Age (Dordrecht, Netherlands) 2014;36(4):9687

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Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

Rojanathammanee L, Rakoczy S, Brown-Borg HM
The journals of gerontology. Series A, Biological sciences and medical sciences 2014 Oct;69(10):1199-211

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Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.

Shirai M, Arakawa S, Miida H, Matsuyama T, Kinoshita J, Makino T, Kai K, Teranishi M
Journal of toxicologic pathology 2013 Jun;26(2):175-86

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse liver tissue were subjected to SDS PAGE followed by western blot with 14475-1-AP(GSTA1 antibody) at dilution of 1:400

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using GSTA1 antibody 14475-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human liver using 14475-1-AP(GSTA1 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human liver using 14475-1-AP(GSTA1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue