Tissue expression
Cell line expression
Protein structure

GSTA3

Glutathione S-transferase alpha 3
 
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
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309 antibodies from 29 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
10 antibodies
antibodies-online
79 antibodies
NovoPro Bioscience Inc.
4 antibodies
OriGene
4 antibodies
Novus Biologicals
4 antibodies
Abnova Corporation
4 antibodies
Acris Antibodies GmbH
2 antibodies
FineTest Biotech
1 antibody
Cusabio Biotech Co., Ltd
3 antibodies
St John's Laboratory
3 antibodies
Abgent
2 antibodies
Antibodies.com
2 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
2 antibodies
Aviva Systems Biology
3 antibodies
MyBioSource
8 antibodies
ProSci
1 antibody
Abbexa
6 antibodies
GeneTex
3 antibodies
Creative Biolabs
15 antibodies
Creative Diagnostics
3 antibodies
Affinity Biosciences
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
26 antibodies
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
1 antibody