Tissue expression
Cell line expression

GSTA3

gene product
 
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
More gene data

Antibodies

 

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317 antibodies from 29 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
102 antibodies
antibodies-online
79 antibodies
NovoPro Bioscience Inc.
4 antibodies
OriGene
4 antibodies
Novus Biologicals
4 antibodies
Abnova Corporation
4 antibodies
Acris Antibodies GmbH
2 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Cusabio Biotech Co., Ltd
3 antibodies
Invitrogen Antibodies
8 antibodies
Abgent
2 antibodies
Biorbyt
15 antibodies
Antibodies.com
2 antibodies
NSJ Bioreagents
2 antibodies
Aviva Systems Biology
3 antibodies
MyBioSource
8 antibodies
ProSci
1 antibody
Abbexa
6 antibodies
GeneTex
3 antibodies
Creative Diagnostics
3 antibodies
Affinity Biosciences
1 antibody
RayBiotech, Inc.
1 antibody
St John's Laboratory
1 antibody
United States Biological
26 antibodies
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
1 antibody
Creative Biolabs
13 antibodies