Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- ABIN2846280 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 152-187), (BH3 Domain), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 152-187, BH3 Domain, N-Term
- Antibody clone number
- RB3385
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Autophagy and Bcl-2/BNIP3 death regulatory pathway in non-small cell lung carcinomas.
Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments.
Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress.
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.
Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence.
Karpathiou G, Sivridis E, Koukourakis M, Mikroulis D, Bouros D, Froudarakis M, Bougioukas G, Maltezos E, Giatromanolaki A
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2013 Jul;121(7):592-604
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2013 Jul;121(7):592-604
Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments.
Wojtkowiak JW, Rothberg JM, Kumar V, Schramm KJ, Haller E, Proemsey JB, Lloyd MC, Sloane BF, Gillies RJ
Cancer research 2012 Aug 15;72(16):3938-47
Cancer research 2012 Aug 15;72(16):3938-47
Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress.
Metukuri MR, Beer-Stolz D, Namas RA, Dhupar R, Torres A, Loughran PA, Jefferson BS, Tsung A, Billiar TR, Vodovotz Y, Zamora R
American journal of physiology. Gastrointestinal and liver physiology 2009 Mar;296(3):G499-509
American journal of physiology. Gastrointestinal and liver physiology 2009 Mar;296(3):G499-509
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.
Kothari S, Cizeau J, McMillan-Ward E, Israels SJ, Bailes M, Ens K, Kirshenbaum LA, Gibson SB
Oncogene 2003 Jul 24;22(30):4734-44
Oncogene 2003 Jul 24;22(30):4734-44
Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence.
Yasuda M, Theodorakis P, Subramanian T, Chinnadurai G
The Journal of biological chemistry 1998 May 15;273(20):12415-21
The Journal of biological chemistry 1998 May 15;273(20):12415-21
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Supportive validation
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC