Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- HPA003015 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA003015, RRID:AB_1078290
- Product name
- Anti-BNIP3
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human BNIP3, Gene description: BCL2/adenovirus E1B 19kDa interacting protein 3, Alternative Gene Names: Nip3, Validated applications: WB, IHC, Uniprot ID: Q12983, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner
BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis
Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia
BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver
Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
Berardi D, Bock-Hughes A, Terry A, Drake L, Bozek G, Macleod K
Science Advances 2022;8(41)
Science Advances 2022;8(41)
BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis
Vara‐Pérez M, Rossi M, Van den Haute C, Maes H, Sassano M, Venkataramani V, Michalke B, Romano E, Rillaerts K, Garg A, Schepkens C, Bosisio F, Wouters J, Oliveira A, Vangheluwe P, Annaert W, Swinnen J, Colet J, van den Oord J, Fendt S, Mazzone M, Agostinis P
The EMBO Journal 2021;40(10)
The EMBO Journal 2021;40(10)
Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia
Thomas L, Esposito C, Morgan R, Price S, Young J, Williams S, Maddalena L, McDermott U, Ashcroft M
Communications Biology 2021;4(1)
Communications Biology 2021;4(1)
BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver
Springer M, Poole L, Drake L, Bock-Hughes A, Boland M, Smith A, Hart J, Chourasia A, Liu I, Bozek G, Macleod K
Autophagy 2021;17(11):3530-3546
Autophagy 2021;17(11):3530-3546
Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
Chourasia A, Tracy K, Frankenberger C, Boland M, Sharifi M, Drake L, Sachleben J, Asara J, Locasale J, Karczmar G, Macleod K
EMBO reports 2015;16(9):1145-1163
EMBO reports 2015;16(9):1145-1163
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