Tissue expression
Cell line expression
Protein structure
LOXL4
Lysyl oxidase like 4FLJ21889, LOXC
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | H00084171-M01 | 3 references | Monoclonal |
WB
EL |
|
antibodies-online | ABIN566544 | 2 references | Polyclonal |
WB
EL |
|
Enzo Life Sciences | ALX-215-067-R050 | 2 references | Polyclonal |
WB
ICC
IHC
FC |
|
Invitrogen Antibodies | BS-5790R | Polyclonal |
WB
EL
IHC
|
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Abnova Corporation | H00084171-A01 | 2 references | Polyclonal |
WB
|
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