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- References [143]
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- Product number
- 16473-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Aquaporin 4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Aquaporin 4 antibody (Cat. #16473-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease-Like Non-Human Primate Model.
Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury.
Astrocytes differentiated from patient iPSCs model the rare leukodystrophy MLC and uncover disease-linked maturation defects and Kir4.1 channel dysfunction.
Aquaporin-4 deficiency induced white matter injury via upregulated complement component 3 in cerebral small vessel disease.
Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts.
Aquaporin 4 and its isoforms regulation ameliorate AQP4 Mis-localization-induced glymphatic dysfunction in ischemic stroke.
Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC.
Mitochondrial transfer from glia to neurons protects against peripheral neuropathy.
Aquaporin-4-overexpressing mesenchymal stem cells promote neurological recovery after intracerebral hemorrhage by inhibiting TLR4/NF-κB signaling.
Nao-Xin-Tong Capsule alleviates astrocyte end-foot swelling after cerebral ischemia-reperfusion injury via NF-κB/MMP9/AQP4 signal and NF-κB/CXCL12/CXCR4 signal.
Inhibition of Transglutaminase 2 Preserves Blood-Brain Barrier Integrity and Improves Neurological Outcomes After Experimental Traumatic Brain Injury in Mice.
Multimodal MR Imaging Reveals the Mechanisms of Post-Cardiac-Arrest Brain edema: Ferroptosis-Mediated BBB Disruption and AQP4 Dysfunction.
Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction.
Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3.
MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer.
Impaired glymphatic transport in hypoxic-ischemic encephalopathy.
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.
Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke.
Reverse translational research of transient magnetic resonance imaging hyperintensity following intracranial stem cell therapy.
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Abnormal neurovascular coupling induces glymphatic dysfunction in a mouse model of familial hemiplegic migraine type 2.
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Glial scarring limits recovery following decompressive surgery in rats with syringomyelia.
Effects of florfenicol on body weight, intestinal inflammatory response, intestinal fluid metabolism and microorganisms in broilers.
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease.
L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.
Melatonin attenuates brain edema via the PI3K/Akt/Nrf2 pathway in rats with cerebral ischemia-reperfusion injury.
AQP-4 autoantibodies as potential early diagnostic biomarkers for NEC.
Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2.
Tianqi pingchan granule promotes recovery of glymphatic system function in a rat model of l-DOPA-induced dyskinesia.
Peiyuan Ningshen-ointment alleviates learning and memory impairment induced by sleep deprivation through activating the cAMP/PKA signaling pathway.
Single-cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.
NOTCH3 Mutation Causes Glymphatic Impairment and Promotes Brain Senescence in CADASIL.
Electroacupuncture alleviated chronic cerebral hypoperfusion damages via targeting aquaporin 4 to prevent amyloid-beta accumulation.
Circadian rhythm disruptions exacerbate inner ear damage in a murine endolymphatic hydrops model.
Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology.
Multi-omics analysis delineates molecular signatures of spinal ependymal tumor.
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation.
Omega-3 Polyunsaturated Fatty Acids Prevent Sevoflurane-induced Cognitive and Fine Motor Dysfunctions in Neonatal Mice by Enhancing Phosphorylated Tau Glymphatic System Clearance Pathway.
Adiphenine Alleviates Impulsive-Like Behaviors in Aged Mice by Inhibiting Nicotinic Acetylcholine Receptors.
Neuroprotective effects of human umbilical cord mesenchymal stem cells (Neuroncell-EX) in a rat model of ischemic stroke are mediated by immunomodulation, blood-brain barrier integrity, angiogenesis, and neurogenesis.
Neuroprotective Effects of AER-271 in a tMCAO Mouse Model: Modulation of Autophagy, Apoptosis, and Inflammation.
Astrocytes, via RTP801, contribute to cognitive decline by disrupting GABAergic-regulated connectivity and driving neuroinflammation in an Alzheimer's disease mouse model.
Distinct roles of A1/A2 astrocytes in blood-brain barrier injury following cerebral I/R via the ROCK/NF-κB and STAT3 pathways.
Identification of the core regulatory program driving NEUROD1-induced neuronal reprogramming.
Liquiritin ameliorates painful diabetic neuropathy in SD rats by inhibiting NLRP3-MMP-9-mediated reversal of aquaporin-4 polarity in the glymphatic system.
Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice.
Effects and mechanisms of sciadonic acid on colonic transit function through regulating 5-HT4/cAMP/PKA/AQP4 signaling pathway in STC model mice.
Disulfiram attenuates cell and tissue damage and blood‒brain barrier dysfunction after intracranial haemorrhage by inhibiting the classical pyroptosis pathway.
Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study.
AQP4 is upregulated in schizophrenia and Its inhibition attenuates MK-801-induced schizophrenia-like behaviors in mice.
Taurine Reverses Arsenic-Induced Inhibition of Hippocampal Neurogenesis and Depression-Like Behavior in Mice.
A Potential Use of Vidarabine: Alleviation of Functional Constipation Through Modulation of the Adenosine A2A Receptor-MLC Signaling Pathway and the Gut Microbiota.
A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.
PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome.
The rhizomes of Atractylodes macrocephala Koidz improve gastrointestinal health and pregnancy outcomes in pregnant mice via modulating intestinal barrier and water-fluid metabolism.
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.
Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system.
Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Ginkgolide B can alleviate spinal cord glymphatic system dysfunction and provide neuroprotection in painful diabetic neuropathy rats by inhibiting matrix metalloproteinase-9.
Short-chain fatty acids suppresses astrocyte activation by amplifying Trp-AhR-AQP4 signaling in experimental autoimmune encephalomyelitis mice.
Global profiling of protein lactylation in microglia in experimental high-altitude cerebral edema.
Reduction of claudin-5 and aquaporin-4 in the rat hippocampal CA-1 and CA-3 regions of a learned helplessness model of depression.
A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau.
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.
Aquaporin 4 Mediates the Effect of Iron Overload on Hydrocephalus After Intraventricular Hemorrhage.
TGN-020 ameliorates motor dysfunction post-spinal cord injury via enhancing astrocyte autophagy and mitigating inflammation by activating AQP4/PPAR-γ/mTOR pathway.
Role of intermittent hypoxic training combined with methazolamide in the prevention of high-altitude cerebral edema in rats.
The impact of X-rays on cardiac hydrometabolism and the regulatory role of AS-IV.
Depleting parenchymal border macrophages alleviates cerebral edema and neuroinflammation following status epilepticus.
The Phenotype Changes of Astrocyte During Different Ischemia Conditions.
β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice.
Impacts of Age and Gender on Brain Edema in a Mouse Water Intoxication Model.
Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model.
Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain.
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.
Functional Water Channels Within the TSH Receptor: A New Paradigm for TSH Action With Disease Implications.
Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Glial Cell Adhesion Molecule (GlialCAM) Determines Proliferative versus Invasive Cell States in Glioblastoma.
Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression.
Ganoderma lucidum polysaccharides ameliorates D-galactose-induced aging salivary secretion disorders by upregulating the rhythm and aquaporins.
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Effects of different dietary protein levels on intestinal aquaporins in weaned piglets.
Experimental study on the effect of chlorhexidine gluconate (CG)-induced atrial fibrillation on renal water and sodium metabolism.
A novel purgative mechanism of multiflorin A involves changing intestinal glucose absorption and permeability.
High-titer AAV disrupts cerebrovascular integrity and induces lymphocyte infiltration in adult mouse brain.
Klotho gene might antagonize ischemic injury in stroke rats by reducing the expression of AQP4 via P38MAPK pathway.
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Upregulation of TRPC6 inhibits astrocyte activation and proliferation after spinal cord injury in rats by suppressing AQP4 expression.
Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Strategies to Screen Anti-AQP4 Antibodies from Yeast Surface Display Libraries.
Digoxin Ameliorates Glymphatic Transport and Cognitive Impairment in a Mouse Model of Chronic Cerebral Hypoperfusion.
Akt/Aquaporin-4 Signaling Aggravates Neuropathic Pain by Activating Astrocytes after Spinal Nerve Ligation in Rats.
Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway.
RNA-Seq Analysis Reveals Dendrobium officinale Polysaccharides Inhibit Precancerous Lesions of Gastric Cancer through PER3 and AQP4.
Attenuation of cerebral edema facilitates recovery of glymphatic system function after status epilepticus.
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.
Reducing LncRNA-5657 expression inhibits the brain inflammatory reaction in septic rats.
Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes.
Aquaporin 4 inhibition alleviates myocardial ischemia-reperfusion injury by restraining cardiomyocyte pyroptosis.
Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1-transgenic mice.
MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Cerebral Immunohistochemical Characterization of the H(2)S and the Oxytocin Systems in a Porcine Model of Acute Subdural Hematoma.
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte.
Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.
Effect of AQP4-RNAi in treating traumatic brain edema: Multi-modal MRI and histopathological changes of early stage edema in a rat model.
Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.
Higher expression levels of aquaporin (AQP)1 and AQP5 in the lungs of arid-desert living Lepus yarkandensis.
Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation.
Higher Expression Levels of Aquaporin Family of Proteins in the Kidneys of Arid-Desert Living Lepus yarkandensis.
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1.
Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice.
Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production.
Severe white matter astrocytopathy in CADASIL.
TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Aquaporin 4 Silencing Aggravates Hydrocephalus Induced by Injection of Autologous Blood in Rats.
Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration.
Role of vasodilator-stimulated phosphoprotein in human cytomegalovirus-induced hyperpermeability of human endothelial cells.
A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.
Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.
Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.
Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice.
Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.
PROTECTIVE EFFECTS OF ETHYL ACETATE EXTRACTION FROM GASTRODIA ELATA BLUME ON BLOOD-BRAIN BARRIER IN FOCAL CEREBRAL ISCHEMIA REPERFUSION.
Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia.
Expression of aquaporin-4 and pathological characteristics of brain injury in a rat model of traumatic brain injury.
NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy.
Visualization of inflammation and demyelination in 2D2 transgenic mice with rodent MRI.
Jiang Z, Qin Y, Luo B, Bai F, Liu J, Ma L, He S, Chen R, Wang Y, Liu S, Sun Y, Chen Y, Zhang S, Liang J, Liao F, Wei H, Wei J, Wang L, Xu H, Wu Z, Chen G, Lei W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e20239
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e20239
Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury.
Du X, Li SY, Wu GL, Cai HY, Sun CY, Lin H, Cai YF, Wang Q
Rejuvenation research 2026 Jun;29(3):131-145
Rejuvenation research 2026 Jun;29(3):131-145
Astrocytes differentiated from patient iPSCs model the rare leukodystrophy MLC and uncover disease-linked maturation defects and Kir4.1 channel dysfunction.
Lanciotti A, Brignone MS, De Nuccio C, Sposito S, Caprini ES, Belfiore M, Nicita F, Veroni C, Meloni C, Carrozzo R, Rizza T, Aiello C, Sartorelli J, Bertini E, Visentin S, Ambrosini E
Neurobiology of disease 2026 Jan;218:107218
Neurobiology of disease 2026 Jan;218:107218
Aquaporin-4 deficiency induced white matter injury via upregulated complement component 3 in cerebral small vessel disease.
Chen Y, Jiang L, Yao D, Liu D, Pan Y, Wang Y
Journal of neuroinflammation 2026 Jan 21;23(1):65
Journal of neuroinflammation 2026 Jan 21;23(1):65
Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts.
Cyranowski S, Zawadzka M, Ghosh M, Wojtas B, Malik AR, Poleszak K, Waśniewski K, Baluszek S, Swatler J, Wojnicki K, Gielniewski B, Kaza B, Klejman A, Łukasik H, Kaminska B
Cell communication and signaling : CCS 2026 Jan 15;24(1):103
Cell communication and signaling : CCS 2026 Jan 15;24(1):103
Aquaporin 4 and its isoforms regulation ameliorate AQP4 Mis-localization-induced glymphatic dysfunction in ischemic stroke.
Zhang H, Wang J, Zhang S, Yan D, Dong Y, Zhang P, Sun W, Liu X
Journal of advanced research 2026 Feb;80:835-849
Journal of advanced research 2026 Feb;80:835-849
Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC.
Bisseling Q, Passchier EMJ, Kirwan FM, Antonovaite N, Camerini S, Brignone MS, Freal A, Mansvelder HD, Ambrosini E, van der Knaap MS, Min R
Glia 2026 Feb;74(2):e70104
Glia 2026 Feb;74(2):e70104
Mitochondrial transfer from glia to neurons protects against peripheral neuropathy.
Xu J, Li Y, Novak C, Lee M, Yan Z, Bang S, McGinnis A, Chandra S, Zhang V, He W, Lechler T, Rodriguez Salazar MP, Eroglu C, Becker ML, Velmeshev D, Cheney RE, Ji RR
Nature 2026 Feb;650(8103):951-960
Nature 2026 Feb;650(8103):951-960
Aquaporin-4-overexpressing mesenchymal stem cells promote neurological recovery after intracerebral hemorrhage by inhibiting TLR4/NF-κB signaling.
Li Y, Yang W, Tang Y, Tao Z, Li P, Xu B, Zhao X, Lu X
Free radical biology & medicine 2026 Feb 16;244:147-165
Free radical biology & medicine 2026 Feb 16;244:147-165
Nao-Xin-Tong Capsule alleviates astrocyte end-foot swelling after cerebral ischemia-reperfusion injury via NF-κB/MMP9/AQP4 signal and NF-κB/CXCL12/CXCR4 signal.
Shang J, Wei W, Wang B, Wei R, Cui Y, Wang J, Liu X
Journal of ethnopharmacology 2026 Aug 10;367:121761
Journal of ethnopharmacology 2026 Aug 10;367:121761
Inhibition of Transglutaminase 2 Preserves Blood-Brain Barrier Integrity and Improves Neurological Outcomes After Experimental Traumatic Brain Injury in Mice.
Yang J, Zhang L, Qiu X, Wang J, Yan R, Ye J, Peng J, Jiang Y
CNS neuroscience & therapeutics 2026 Apr;32(4):e70887
CNS neuroscience & therapeutics 2026 Apr;32(4):e70887
Multimodal MR Imaging Reveals the Mechanisms of Post-Cardiac-Arrest Brain edema: Ferroptosis-Mediated BBB Disruption and AQP4 Dysfunction.
Tan Y, Ye H, Ge Q, Wang P, Liu Z, Yang Z
Journal of magnetic resonance imaging : JMRI 2026 Apr 3;
Journal of magnetic resonance imaging : JMRI 2026 Apr 3;
Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction.
Wu M, Li D, Qiu F, Nie H, Fang R, Zhong Z, Yang H, Lin X, Wang X, Wen H, Gong L, Meng P
PloS one 2025;20(3):e0316383
PloS one 2025;20(3):e0316383
Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3.
Song J, Huang X, Luo Y, Li M, Ouyang Y, Liu W, Pan H, Luo H
Frontiers in immunology 2025;16:1563602
Frontiers in immunology 2025;16:1563602
MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer.
Bi J, Wang Y, Wang Y
Frontiers in pharmacology 2025;16:1523689
Frontiers in pharmacology 2025;16:1523689
Impaired glymphatic transport in hypoxic-ischemic encephalopathy.
Shen J, Yang Y, Chen F, Zuo Y, Yang Y, Wei W, Liu Y, Wen J
NeuroImage 2025 Sep;318:121414
NeuroImage 2025 Sep;318:121414
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.
Ding Y, Zuo Y, Zhang B, Fan Y, Xu G, Cheng Z, Ma S, Fang S, Tian A, Gao D, Xu X, Wang Q, Jing Y, Jiang M, Xiong M, Li J, Han Z, Sun S, Wang S, He F, Yang J, Qu J, Zhang W, Liu GH
Cell 2025 Oct 2;188(20):5763-5784.e26
Cell 2025 Oct 2;188(20):5763-5784.e26
Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke.
Li Y, Zhou H, Xie J, Yu M, Ye G, Zhang Y, Li Z, Zhang K, Wu J, Xiao S, Zeng S, Chang Y, Huang K, Pan S
Brain pathology (Zurich, Switzerland) 2025 Nov;35(6):e70022
Brain pathology (Zurich, Switzerland) 2025 Nov;35(6):e70022
Reverse translational research of transient magnetic resonance imaging hyperintensity following intracranial stem cell therapy.
Qi Y, Kawabori M, Nakahara Y, Tha KK, Ohtsuki S, Fujimura M
Stem cell research & therapy 2025 Nov 18;16(1):646
Stem cell research & therapy 2025 Nov 18;16(1):646
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Shen Q, Wang X, Ou Q, Wang Q, Zhao Z, Chen Z, Zhu X, Li D, Jin C, Gao F, Wang J, Lu L, Bi Y, Wan W, Guan Y, Xu GT, Xu JY, Tian H
Molecular neurobiology 2025 Nov 14;63(1):41
Molecular neurobiology 2025 Nov 14;63(1):41
Abnormal neurovascular coupling induces glymphatic dysfunction in a mouse model of familial hemiplegic migraine type 2.
Duan C, Wu S, Li Y, Zhang K, Lin C, Yao Y, Wang T, Wang Y
The journal of headache and pain 2025 Nov 13;26(1):257
The journal of headache and pain 2025 Nov 13;26(1):257
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096
European journal of medical research 2025 Nov 10;30(1):1096
Glial scarring limits recovery following decompressive surgery in rats with syringomyelia.
Cui S, Li J, Zhang C, Li Q, Jiang C, Wang X, Yu X, Li K, Feng Y, Jian F
Experimental neurology 2025 Mar;385:115113
Experimental neurology 2025 Mar;385:115113
Effects of florfenicol on body weight, intestinal inflammatory response, intestinal fluid metabolism and microorganisms in broilers.
Shen W, Wang K, Han Y, Wang H, Duan Z
Journal of veterinary science 2025 Mar;26(2):e25
Journal of veterinary science 2025 Mar;26(2):e25
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease.
Liang S, Liu H, Wang X, Lin H, Zheng L, Zhang Y, Peng L, Huang S, Chen L
Brain research bulletin 2025 Mar;222:111263
Brain research bulletin 2025 Mar;222:111263
L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.
Liu K, Dong H, Li X, Hu C, Cui F, Li S, Zhang X, Du Y, Yang P, Ji W, Sui W, Meng J
Foods (Basel, Switzerland) 2025 Mar 6;14(5)
Foods (Basel, Switzerland) 2025 Mar 6;14(5)
Melatonin attenuates brain edema via the PI3K/Akt/Nrf2 pathway in rats with cerebral ischemia-reperfusion injury.
Liu Y, Wang X, Li Z, Gao X, Wu X, Pi J, Wang X, Wang Q, Zhou F, Wang X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108299
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108299
AQP-4 autoantibodies as potential early diagnostic biomarkers for NEC.
Mu Y, Lan C, Chen J, Ouyang Y, Jiang Y, Lv Y, Tian B, Tian Y, Li L, Li H, Hou L, Lu J, Wei P, Lv J, He Q, Liu Y, Zhong W
International immunopharmacology 2025 Jun 26;159:114935
International immunopharmacology 2025 Jun 26;159:114935
Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2.
He Q, Wang Z, Wang Y, Zhu M, Liang Z, Zhang K, Xu Y, Chen G
Neural regeneration research 2025 Jun 1;20(6):1801-1815
Neural regeneration research 2025 Jun 1;20(6):1801-1815
Tianqi pingchan granule promotes recovery of glymphatic system function in a rat model of l-DOPA-induced dyskinesia.
Liu Z, Yang S, Song L, Zhang Y, Wan Y, Gan J, Wu N, Liu Z
Journal of traditional and complementary medicine 2025 Jul;15(4):380-387
Journal of traditional and complementary medicine 2025 Jul;15(4):380-387
Peiyuan Ningshen-ointment alleviates learning and memory impairment induced by sleep deprivation through activating the cAMP/PKA signaling pathway.
Wei XY, Xu FP, Chen XB, Xu Q, Deng LY, Sun C, Chen XY, Tan F, Yang ZM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156469
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156469
Single-cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.
Perez Y, Velmeshev D, Wang L, White ML, Siebert C, Baltazar J, Zuo G, Moriano JA, Chen S, Steffen DM, Dutton NG, Wang S, Wick B, Haeussler M, Chamberlain S, Alvarez-Buylla A, Kriegstein A
Nature communications 2025 Jul 4;16(1):6177
Nature communications 2025 Jul 4;16(1):6177
NOTCH3 Mutation Causes Glymphatic Impairment and Promotes Brain Senescence in CADASIL.
Li C, Li H, Men X, Wang Y, Kang X, Hu M, Su X, Wang S, Lu D, Shen S, Huang H, Deng X, Liu Y, Zhang L, Cai W, Wu A, Lu Z
CNS neuroscience & therapeutics 2025 Jan;31(1):e70140
CNS neuroscience & therapeutics 2025 Jan;31(1):e70140
Electroacupuncture alleviated chronic cerebral hypoperfusion damages via targeting aquaporin 4 to prevent amyloid-beta accumulation.
Zhang Y, Wu L, He K, Cheng Y, Li L, Han D
Neuroreport 2025 Jan 8;36(1):11-21
Neuroreport 2025 Jan 8;36(1):11-21
Circadian rhythm disruptions exacerbate inner ear damage in a murine endolymphatic hydrops model.
Pang B, Bai Y, Chen Y, Zhang S, Xu Z, Li C, Nie Z, Liu H, Guo Z, Ling J, Mei L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70310
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 15;39(1):e70310
Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology.
Rodriguez-Rodriguez P, Wang W, Tsagkogianni C, Feng I, Morello-Megias A, Jain K, Alanko V, Kahvecioglu HA, Mohammadi E, Li X, Flajolet M, Sandebring-Matton A, Maioli S, Vidal N, Milosevic A, Roussarie JP
bioRxiv : the preprint server for biology 2025 Feb 3;
bioRxiv : the preprint server for biology 2025 Feb 3;
Multi-omics analysis delineates molecular signatures of spinal ependymal tumor.
Liu W, Ning C, Geng X, Wang B, Zhang Y, Wang C, Liu Y, Zheng G, Wang Y, Wang X, Li D, Jia W
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1987-2000
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1987-2000
Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation.
Zhao R, Sun B, Wei P, Sun Y, He Q, Zhang K, Lu J, Zhu S, Yang Y, Guo Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e03576
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e03576
Omega-3 Polyunsaturated Fatty Acids Prevent Sevoflurane-induced Cognitive and Fine Motor Dysfunctions in Neonatal Mice by Enhancing Phosphorylated Tau Glymphatic System Clearance Pathway.
Cao T, Jiang S, Di L, Huang P, Cao L, Wang X, Li J, Jin W, Huang L
Molecular neurobiology 2025 Dec 1;63(1):228
Molecular neurobiology 2025 Dec 1;63(1):228
Adiphenine Alleviates Impulsive-Like Behaviors in Aged Mice by Inhibiting Nicotinic Acetylcholine Receptors.
Peng HY, Gao YL, Wang LY, Lv JM, Miao HT, Li LY, Song RX, Zhou TT, An P, Zhao XC, Zhang LM
Journal of neurochemistry 2025 Aug;169(8):e70190
Journal of neurochemistry 2025 Aug;169(8):e70190
Neuroprotective effects of human umbilical cord mesenchymal stem cells (Neuroncell-EX) in a rat model of ischemic stroke are mediated by immunomodulation, blood-brain barrier integrity, angiogenesis, and neurogenesis.
Chin SP, Abd Rahim ENA, Nor Arfuzir NN
In vitro cellular & developmental biology. Animal 2025 Apr;61(4):389-402
In vitro cellular & developmental biology. Animal 2025 Apr;61(4):389-402
Neuroprotective Effects of AER-271 in a tMCAO Mouse Model: Modulation of Autophagy, Apoptosis, and Inflammation.
Mo S, Yang C, Zheng X, Lv H, Mao S, Liu N, Yang Q, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Li X, Shang J
Inflammation 2025 Apr;48(2):713-729
Inflammation 2025 Apr;48(2):713-729
Astrocytes, via RTP801, contribute to cognitive decline by disrupting GABAergic-regulated connectivity and driving neuroinflammation in an Alzheimer's disease mouse model.
Chicote-González A, Solana-Balaguer J, Garcia-Segura P, Campoy-Campos G, Pérez IP, Pérez-Navarro E, Rodríguez MJ, Alberch J, Giralt A, Soria G, Malagelada C
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Apr;21(4):e70051
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Apr;21(4):e70051
Distinct roles of A1/A2 astrocytes in blood-brain barrier injury following cerebral I/R via the ROCK/NF-κB and STAT3 pathways.
Geng Z, Deng G, Wang Z, Xu X, Yin X, Zhang S, Shao J, Wen J
International immunopharmacology 2025 Apr 4;151:114338
International immunopharmacology 2025 Apr 4;151:114338
Identification of the core regulatory program driving NEUROD1-induced neuronal reprogramming.
Li W, Su D, Li X, Lu K, Huang Q, Zheng J, Luo X, Chen G, Fan X
Cell reports 2025 Apr 22;44(4):115523
Cell reports 2025 Apr 22;44(4):115523
Liquiritin ameliorates painful diabetic neuropathy in SD rats by inhibiting NLRP3-MMP-9-mediated reversal of aquaporin-4 polarity in the glymphatic system.
Jia SY, Yin WQ, Xu WM, Li J, Yan W, Lin JY
Frontiers in pharmacology 2024;15:1436146
Frontiers in pharmacology 2024;15:1436146
Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice.
Deng S, Hu Y, Chen S, Xue Y, Yao D, Sun Q, Nedergaard M, Wang W, Ding F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Sep;44(9):1515-1531
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Sep;44(9):1515-1531
Effects and mechanisms of sciadonic acid on colonic transit function through regulating 5-HT4/cAMP/PKA/AQP4 signaling pathway in STC model mice.
Yu Z, Zikela L, Wang D, Wang X, Zhu H, Li S, Han Q
The Journal of nutritional biochemistry 2024 Sep;131:109676
The Journal of nutritional biochemistry 2024 Sep;131:109676
Disulfiram attenuates cell and tissue damage and blood‒brain barrier dysfunction after intracranial haemorrhage by inhibiting the classical pyroptosis pathway.
Xu C, Jiang F, Mao Y, Wei W, Song J, Jia F, Du X, Zhong D, Li G
Scientific reports 2024 Sep 19;14(1):21860
Scientific reports 2024 Sep 19;14(1):21860
Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study.
Jiang F, Cai H, Li H, Yin W, Ouyang S, Hu J, Tu E, Fu K, Yin J, Zhao Z, Yang J, Zeng Q, Yang H
Annals of clinical and translational neurology 2024 Oct;11(10):2769-2784
Annals of clinical and translational neurology 2024 Oct;11(10):2769-2784
AQP4 is upregulated in schizophrenia and Its inhibition attenuates MK-801-induced schizophrenia-like behaviors in mice.
Nie FY, Jin RY, Wu SS, Yuan W, Wu YW, Xue SM, Yang XH, Qiao HF
Behavioural brain research 2024 Oct 18;475:115220
Behavioural brain research 2024 Oct 18;475:115220
Taurine Reverses Arsenic-Induced Inhibition of Hippocampal Neurogenesis and Depression-Like Behavior in Mice.
Liu S, Lei T, Wang L, Chen F, Hu X, Song G, Tang X, Wu G, Chen H, Sun X, Sun W
Journal of biochemical and molecular toxicology 2024 Nov;38(11):e70037
Journal of biochemical and molecular toxicology 2024 Nov;38(11):e70037
A Potential Use of Vidarabine: Alleviation of Functional Constipation Through Modulation of the Adenosine A2A Receptor-MLC Signaling Pathway and the Gut Microbiota.
Gao X, Guo K, Liu S, Yang W, Sheng J, Tian Y, Peng L, Zhao Y
International journal of molecular sciences 2024 Nov 28;25(23)
International journal of molecular sciences 2024 Nov 28;25(23)
A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.
Gao M, Liu Z, Zang H, Wu X, Yan Y, Lin H, Yuan J, Liu T, Zhou Y, Liu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Nov 1;30(21):4876-4886
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Nov 1;30(21):4876-4886
PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome.
Yang Y, Zhang H, Xiao X, Guo M
DNA and cell biology 2024 May;43(5):207-218
DNA and cell biology 2024 May;43(5):207-218
The rhizomes of Atractylodes macrocephala Koidz improve gastrointestinal health and pregnancy outcomes in pregnant mice via modulating intestinal barrier and water-fluid metabolism.
Chenxing W, Jie S, Yajuan T, Ting L, Yuying Z, Suhong C, Guiyuan L
Journal of ethnopharmacology 2024 May 23;326:117971
Journal of ethnopharmacology 2024 May 23;326:117971
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Su Q, Su C, Zhang Y, Guo Y, Liu Y, Liu Y, Yong VW, Xue M
International immunopharmacology 2024 May 10;132:111962
International immunopharmacology 2024 May 10;132:111962
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Song Y, Xue T, Guo S, Yu Z, Yun C, Zhao J, Song Z, Liu Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.
Silbert LC, Roese NE, Krajbich V, Hurworth J, Lahna D, Schwartz DL, Dodge HH, Woltjer RL
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):3839-3851
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):3839-3851
Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system.
Wu X, Wen G, Yan L, Wang Y, Ren X, Li G, Luo Y, Shang J, Lu L, Hermenean A, Yao J, Li B, Lu Y, Wu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116739
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116739
Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice.
Wang S, Yu X, Cheng L, Ren W, Wen G, Wu X, Lou H, Ren X, Lu L, Hermenean A, Yao J, Li B, Lu Y, Wu X
Cell death & disease 2024 Jun 25;15(6):448
Cell death & disease 2024 Jun 25;15(6):448
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Ginkgolide B can alleviate spinal cord glymphatic system dysfunction and provide neuroprotection in painful diabetic neuropathy rats by inhibiting matrix metalloproteinase-9.
Li J, Jia S, Song Y, Xu W, Lin J
Neuropharmacology 2024 Jun 1;250:109907
Neuropharmacology 2024 Jun 1;250:109907
Short-chain fatty acids suppresses astrocyte activation by amplifying Trp-AhR-AQP4 signaling in experimental autoimmune encephalomyelitis mice.
Lin X, Peng Y, Guo Z, He W, Guo W, Feng J, Lu L, Liu Q, Xu P
Cellular and molecular life sciences : CMLS 2024 Jul 8;81(1):293
Cellular and molecular life sciences : CMLS 2024 Jul 8;81(1):293
Global profiling of protein lactylation in microglia in experimental high-altitude cerebral edema.
Jiang X, Gao J, Fei X, Geng Y, Yue X, Shi Z, Cheng X, Zhao T, Fan M, Wu H, Zhao M, Zhu L
Cell communication and signaling : CCS 2024 Jul 25;22(1):374
Cell communication and signaling : CCS 2024 Jul 25;22(1):374
Reduction of claudin-5 and aquaporin-4 in the rat hippocampal CA-1 and CA-3 regions of a learned helplessness model of depression.
Hirose Y, Oda Y, Yoshino K, Yano F, Kimura M, Kimura H, Iyo M, Shirayama Y
Pharmacology, biochemistry, and behavior 2024 Jan;234:173676
Pharmacology, biochemistry, and behavior 2024 Jan;234:173676
A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau.
Jiang Z, Wang J, Qin Y, Liu S, Luo B, Bai F, Wei H, Zhang S, Wei J, Ding G, Ma L, He S, Chen R, Sun Y, Chen Y, Wang L, Xu H, Wang X, Chen G, Lei W
Alzheimer's research & therapy 2024 Jan 27;16(1):22
Alzheimer's research & therapy 2024 Jan 27;16(1):22
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.
Li X, Xie Z, Zhou Q, Tan X, Meng W, Pang Y, Huang L, Ding Z, Hu Y, Li R, Huang G, Li H
Molecular neurobiology 2024 Feb;61(2):1175-1186
Molecular neurobiology 2024 Feb;61(2):1175-1186
Aquaporin 4 Mediates the Effect of Iron Overload on Hydrocephalus After Intraventricular Hemorrhage.
Li Y, Nan D, Liu R, Li J, Zhang Z, Deng J, Zhang Y, Yan Z, Hou C, Yao E, Sun W, Wang Z, Huang Y
Neurocritical care 2024 Feb;40(1):225-236
Neurocritical care 2024 Feb;40(1):225-236
TGN-020 ameliorates motor dysfunction post-spinal cord injury via enhancing astrocyte autophagy and mitigating inflammation by activating AQP4/PPAR-γ/mTOR pathway.
Kong J, Zhang Q, Zheng H, Tang D, Fang L, An S, Li J, Fan Z
Experimental neurology 2024 Dec;382:114975
Experimental neurology 2024 Dec;382:114975
Role of intermittent hypoxic training combined with methazolamide in the prevention of high-altitude cerebral edema in rats.
Peng W, Ma H, Zhao R, Xu S, Lv M, Jing B, Hu Z
Scientific reports 2024 Dec 4;14(1):30252
Scientific reports 2024 Dec 4;14(1):30252
The impact of X-rays on cardiac hydrometabolism and the regulatory role of AS-IV.
Shangzu Z, Qiyang L, Sichao D, Yutong W, Yangyang L, Yan C, Gengqiang Y, Ting Z, Zhiming M, Fuxian L, Liying Z, Yongqi L
International immunopharmacology 2024 Dec 25;143(Pt 3):113533
International immunopharmacology 2024 Dec 25;143(Pt 3):113533
Depleting parenchymal border macrophages alleviates cerebral edema and neuroinflammation following status epilepticus.
Lin R, Luo R, Yu X, Zou J, Huang X, Guo Y
Journal of translational medicine 2024 Dec 2;22(1):1094
Journal of translational medicine 2024 Dec 2;22(1):1094
The Phenotype Changes of Astrocyte During Different Ischemia Conditions.
Meng F, Cui J, Wang P, Wang J, Sun J, Li L
Brain sciences 2024 Dec 14;14(12)
Brain sciences 2024 Dec 14;14(12)
β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice.
Tan X, Li X, Li R, Meng W, Xie Z, Li J, Pang Y, Huang G, Li L, Li H
Experimental neurology 2024 Aug;378:114819
Experimental neurology 2024 Aug;378:114819
Impacts of Age and Gender on Brain Edema in a Mouse Water Intoxication Model.
Nakamura-Maruyama E, Irie K, Narita K, Himi N, Miyamoto O, Nakamura T
Acta medica Okayama 2024 Apr;78(2):115-122
Acta medica Okayama 2024 Apr;78(2):115-122
Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model.
Wen G, Zhan X, Xu X, Xia X, Jiang S, Ren X, Ren W, Lou H, Lu L, Hermenean A, Yao J, Gao L, Li B, Lu Y, Wu X
Molecular neurobiology 2024 Apr;61(4):2049-2062
Molecular neurobiology 2024 Apr;61(4):2049-2062
Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain.
Hasegawa H, Kondo M
Biological & pharmaceutical bulletin 2023;46(9):1194-1202
Biological & pharmaceutical bulletin 2023;46(9):1194-1202
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.
Fan Y, Yang Y, Lin K, Zhou X, Li Y, Lin Q
Open medicine (Warsaw, Poland) 2023;18(1):20230800
Open medicine (Warsaw, Poland) 2023;18(1):20230800
Functional Water Channels Within the TSH Receptor: A New Paradigm for TSH Action With Disease Implications.
Latif R, Davies TF, Mezei M
Endocrinology 2023 Sep 23;164(11)
Endocrinology 2023 Sep 23;164(11)
Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.
Perez Y, Velmeshev D, Wang L, White M, Siebert C, Baltazar J, Dutton NG, Wang S, Haeussler M, Chamberlain S, Kriegstein A
bioRxiv : the preprint server for biology 2023 Sep 22;
bioRxiv : the preprint server for biology 2023 Sep 22;
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Yao D, Li R, Hao J, Huang H, Wang X, Ran L, Fang Y, He Y, Wang W, Liu X, Wang M
Translational psychiatry 2023 Oct 6;13(1):310
Translational psychiatry 2023 Oct 6;13(1):310
Glial Cell Adhesion Molecule (GlialCAM) Determines Proliferative versus Invasive Cell States in Glioblastoma.
De A, Lattier JM, Morales JE, Kelly JR, Zheng X, Chen Z, Sebastian S, Nassiri Toosi Z, Huse JT, Lang FF, McCarty JH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Nov 22;43(47):8043-8057
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Nov 22;43(47):8043-8057
Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression.
Wang R, Peng L, Xiao Y, Zhou Q, Wang Z, Tang L, Xiao H, Yang K, Liu H, Li L
Cancer gene therapy 2023 May;30(5):716-726
Cancer gene therapy 2023 May;30(5):716-726
Ganoderma lucidum polysaccharides ameliorates D-galactose-induced aging salivary secretion disorders by upregulating the rhythm and aquaporins.
Wu M, Huang B, Hu L, Zhang T, Zhang B, Zhao X, Lu R, Xiong W, Zhang S, Li J, Chen D, Yang B, Li G, Ran J
Experimental gerontology 2023 May;175:112147
Experimental gerontology 2023 May;175:112147
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Yao F, Luo Y, Chen Y, Li Y, Hu X, You X, Li Z, Yu S, Tian D, Zheng M, Cheng L, Jing J
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Effects of different dietary protein levels on intestinal aquaporins in weaned piglets.
Ren Z, Zhang X, Fan H, Yu Y, Yao S, Wang Y, Dong Y, Deng H, Zuo Z, Deng Y, Wang Y, Xu Z, Deng J
Journal of animal physiology and animal nutrition 2023 Mar;107(2):541-555
Journal of animal physiology and animal nutrition 2023 Mar;107(2):541-555
Experimental study on the effect of chlorhexidine gluconate (CG)-induced atrial fibrillation on renal water and sodium metabolism.
Li S, Pei H, Huang Y, Liu D, Yang L, Zhang Q, Wang Z
Scientific reports 2023 Mar 10;13(1):4016
Scientific reports 2023 Mar 10;13(1):4016
A novel purgative mechanism of multiflorin A involves changing intestinal glucose absorption and permeability.
Zhao Z, Zuo X, Han C, Zhang Y, Zhao J, Wang Y, Zhang S, Li W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154805
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154805
High-titer AAV disrupts cerebrovascular integrity and induces lymphocyte infiltration in adult mouse brain.
Guo Y, Chen J, Ji W, Xu L, Xie Y, He S, Lai C, Hou K, Li Z, Chen G, Wu Z
Molecular therapy. Methods & clinical development 2023 Dec 14;31:101102
Molecular therapy. Methods & clinical development 2023 Dec 14;31:101102
Klotho gene might antagonize ischemic injury in stroke rats by reducing the expression of AQP4 via P38MAPK pathway.
Zhu G, Xiang T, Liang S, Liu K, Xiao Z, Ye Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107205
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107205
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050
Journal of ethnopharmacology 2023 Apr 24;306:116050
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Luo K, Wang Y, Chen WS, Feng X, Liao Y, Chen S, Liu Y, Liao C, Chen M, Ao L
Neural plasticity 2022;2022:5241449
Neural plasticity 2022;2022:5241449
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948
Frontiers in pharmacology 2022;13:834948
Upregulation of TRPC6 inhibits astrocyte activation and proliferation after spinal cord injury in rats by suppressing AQP4 expression.
Cai J, Kong J, Ma S, Ban Y, Li J, Fan Z
Brain research bulletin 2022 Nov;190:12-21
Brain research bulletin 2022 Nov;190:12-21
Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Qin X, Wang J, Chen S, Liu G, Wu C, Lv Q, He X, Bai X, Huang W, Liao H
Glia 2022 May;70(5):892-912
Glia 2022 May;70(5):892-912
Strategies to Screen Anti-AQP4 Antibodies from Yeast Surface Display Libraries.
Huang A, Jin W, Fahad AS, Mussman BK, Nicchia GP, Madan B, de Souza MO, Griffin JD, Bennett JL, Frigeri A, Berkland CJ, DeKosky BJ
Antibodies (Basel, Switzerland) 2022 Jun 5;11(2)
Antibodies (Basel, Switzerland) 2022 Jun 5;11(2)
Digoxin Ameliorates Glymphatic Transport and Cognitive Impairment in a Mouse Model of Chronic Cerebral Hypoperfusion.
Cao J, Yao D, Li R, Guo X, Hao J, Xie M, Li J, Pan D, Luo X, Yu Z, Wang M, Wang W
Neuroscience bulletin 2022 Feb;38(2):181-199
Neuroscience bulletin 2022 Feb;38(2):181-199
Akt/Aquaporin-4 Signaling Aggravates Neuropathic Pain by Activating Astrocytes after Spinal Nerve Ligation in Rats.
Guo S, Song Z, He J, Yin G, Zhu J, Liu H, Yang L, Ji X, Xu X, Liu Z, Liu J
Neuroscience 2022 Feb 1;482:116-131
Neuroscience 2022 Feb 1;482:116-131
Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway.
Zhang M, Zhang B, Chen R, Li M, Zheng Z, Xu W, Zhang Y, Gong S, Hu Q
Viruses 2022 Apr 18;14(4)
Viruses 2022 Apr 18;14(4)
RNA-Seq Analysis Reveals Dendrobium officinale Polysaccharides Inhibit Precancerous Lesions of Gastric Cancer through PER3 and AQP4.
Zhao Y, Huang HX, Tang SY, Sun YZ
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3036504
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3036504
Attenuation of cerebral edema facilitates recovery of glymphatic system function after status epilepticus.
Liu K, Zhu J, Chang Y, Lin Z, Shi Z, Li X, Chen X, Lin C, Pan S, Huang K
JCI insight 2021 Sep 8;6(17)
JCI insight 2021 Sep 8;6(17)
Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.
Ma X, Qin C, Chen M, Yu HH, Chu YH, Chen TJ, Bosco DB, Wu LJ, Bu BT, Wang W, Tian DS
Journal of neuroinflammation 2021 Sep 15;18(1):201
Journal of neuroinflammation 2021 Sep 15;18(1):201
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Xing C, Zhou Y, Xu H, Ding M, Zhang Y, Zhang M, Hu M, Huang X, Song L
Neuroscience research 2021 Oct;171:124-132
Neuroscience research 2021 Oct;171:124-132
Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.
Jiang H, Li H, Cao Y, Zhang R, Zhou L, Zhou Y, Zeng X, Wu J, Wu D, Wu D, Guo X, Li X, Wu H, Li P
Brain research 2021 Oct 1;1768:147586
Brain research 2021 Oct 1;1768:147586
Reducing LncRNA-5657 expression inhibits the brain inflammatory reaction in septic rats.
Zhan YA, Qiu XL, Wang XZ, Zhao N, Qian KJ
Neural regeneration research 2021 Jul;16(7):1288-1293
Neural regeneration research 2021 Jul;16(7):1288-1293
Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes.
Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Perez Y, Mostajo-Radji MA, Wang S, Velmeshev D, Salma J, Kumar GR, Pollen AA, Crouch EE, Ott M, Kriegstein AR
bioRxiv : the preprint server for biology 2021 Jan 18;
bioRxiv : the preprint server for biology 2021 Jan 18;
Aquaporin 4 inhibition alleviates myocardial ischemia-reperfusion injury by restraining cardiomyocyte pyroptosis.
Jiang Q, Dong X, Hu D, Chen L, Luo Y
Bioengineered 2021 Dec;12(1):9021-9030
Bioengineered 2021 Dec;12(1):9021-9030
Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1-transgenic mice.
Quan W, Luo Q, Hao W, Tomic I, Furihata T, Schulz-Schäffer W, Menger MD, Fassbender K, Liu Y
Glia 2021 Aug;69(8):1987-2005
Glia 2021 Aug;69(8):1987-2005
MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies.
Li Y, Fan C, Wang L, Lan T, Gao R, Wang W, Yu SY
The Journal of clinical investigation 2021 Aug 16;131(16)
The Journal of clinical investigation 2021 Aug 16;131(16)
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
Cerebral Immunohistochemical Characterization of the H(2)S and the Oxytocin Systems in a Porcine Model of Acute Subdural Hematoma.
Denoix N, Merz T, Unmuth S, Hoffmann A, Nespoli E, Scheuerle A, Huber-Lang M, Gündel H, Waller C, Radermacher P, McCook O
Frontiers in neurology 2020;11:649
Frontiers in neurology 2020;11:649
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901
Molecular neurobiology 2020 Sep;57(9):3891-3901
Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte.
Liu M, Xu Z, Wang L, Zhang L, Liu Y, Cao J, Fu Q, Liu Y, Li H, Lou J, Hou W, Mi W, Ma Y
Journal of neuroinflammation 2020 Sep 11;17(1):270
Journal of neuroinflammation 2020 Sep 11;17(1):270
Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.
Liu X, Hao J, Yao E, Cao J, Zheng X, Yao D, Zhang C, Li J, Pan D, Luo X, Wang M, Wang W
Brain, behavior, and immunity 2020 Oct;89:357-370
Brain, behavior, and immunity 2020 Oct;89:357-370
Effect of AQP4-RNAi in treating traumatic brain edema: Multi-modal MRI and histopathological changes of early stage edema in a rat model.
Guan Y, Li L, Chen J, Lu H
Experimental and therapeutic medicine 2020 Mar;19(3):2029-2036
Experimental and therapeutic medicine 2020 Mar;19(3):2029-2036
Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.
Wang H, Chen H, Jin J, Liu Q, Zhong D, Li G
Life sciences 2020 Jun 15;251:117638
Life sciences 2020 Jun 15;251:117638
Higher expression levels of aquaporin (AQP)1 and AQP5 in the lungs of arid-desert living Lepus yarkandensis.
Zhang J, Li S, Liu J, Li L, Deng F, Baikeli B, Li L, Ma X, Liu G
Journal of animal physiology and animal nutrition 2020 Jul;104(4):1186-1195
Journal of animal physiology and animal nutrition 2020 Jul;104(4):1186-1195
Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation.
Shimizu M, Okuno T, Kinoshita M, Sumi H, Fujimura H, Yamashita K, Sugimoto T, Sakakibara S, Sakakibara K, Koda T, Tada S, Ishikura T, Murata H, Beppu S, Shiraishi N, Sugiyama Y, Nakatsuji Y, Kumanogoh A, Mochizuki H
Scientific reports 2020 Aug 6;10(1):13274
Scientific reports 2020 Aug 6;10(1):13274
Higher Expression Levels of Aquaporin Family of Proteins in the Kidneys of Arid-Desert Living Lepus yarkandensis.
Zhang J, Li S, Deng F, Baikeli B, Huang S, Wang B, Liu G
Frontiers in physiology 2019;10:1172
Frontiers in physiology 2019;10:1172
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G
Scientific reports 2019 Nov 12;9(1):16639
Scientific reports 2019 Nov 12;9(1):16639
PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1.
Huang B, Miao H, Yuan Y, Qiu F, Liu X, Liu Z, Zhang H, Zhao Q, Wang M, Dong H, Zhang Z
International journal of molecular medicine 2019 May;43(5):1979-1990
International journal of molecular medicine 2019 May;43(5):1979-1990
Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice.
Fang Y, Tian Y, Huang Q, Wan Y, Xu L, Wang W, Pan D, Zhu S, Xie M
Journal of neuroinflammation 2019 May 9;16(1):96
Journal of neuroinflammation 2019 May 9;16(1):96
Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production.
Cotzomi E, Stathopoulos P, Lee CS, Ritchie AM, Soltys JN, Delmotte FR, Oe T, Sng J, Jiang R, Ma AK, Vander Heiden JA, Kleinstein SH, Levy M, Bennett JL, Meffre E, O'Connor KC
Brain : a journal of neurology 2019 Jun 1;142(6):1598-1615
Brain : a journal of neurology 2019 Jun 1;142(6):1598-1615
Severe white matter astrocytopathy in CADASIL.
Hase Y, Chen A, Bates LL, Craggs LJL, Yamamoto Y, Gemmell E, Oakley AE, Korolchuk VI, Kalaria RN
Brain pathology (Zurich, Switzerland) 2018 Nov;28(6):832-843
Brain pathology (Zurich, Switzerland) 2018 Nov;28(6):832-843
TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types.
Khalfallah Y, Kuta R, Grasmuck C, Prat A, Durham HD, Vande Velde C
Scientific reports 2018 May 15;8(1):7551
Scientific reports 2018 May 15;8(1):7551
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Zhang Z, Zhang L, Chen J, Cao Y, Qu M, Lin X, Han Z, Ji X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Aquaporin 4 Silencing Aggravates Hydrocephalus Induced by Injection of Autologous Blood in Rats.
Guo J, Mi X, Zhan R, Li M, Wei L, Sun J
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 20;24:4204-4212
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 20;24:4204-4212
Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration.
Tian Y, Xu L, He Y, Xu X, Li K, Ma Y, Gao Y, Wei D, Wei L
Oncology letters 2018 Aug;16(2):2151-2160
Oncology letters 2018 Aug;16(2):2151-2160
Role of vasodilator-stimulated phosphoprotein in human cytomegalovirus-induced hyperpermeability of human endothelial cells.
Tian Y, He Y, Zhang L, Zhang J, Xu L, Ma Y, Xu X, Wei L
Experimental and therapeutic medicine 2018 Aug;16(2):1295-1303
Experimental and therapeutic medicine 2018 Aug;16(2):1295-1303
A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.
Zhang DD, Zou MJ, Zhang YT, Fu WL, Xu T, Wang JX, Xia WR, Huang ZG, Gan XD, Zhu XM, Xu DG
Experimental neurology 2017 Nov;297:1-13
Experimental neurology 2017 Nov;297:1-13
Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.
Shepard MJ, Padmanaban V, Edwards NA, Chittiboina P, Ray-Chaudhury A, Heiss JD
World neurosurgery 2017 Nov;107:1046.e1-1046.e7
World neurosurgery 2017 Nov;107:1046.e1-1046.e7
Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.
He F, Duan X, Dai R, Li Y, Lin Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265
Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice.
Zhou Y, Huang X, Zhao T, Qiao M, Zhao X, Zhao M, Xu L, Zhao Y, Wu L, Wu K, Chen R, Fan M, Zhu L
Brain, behavior, and immunity 2017 Aug;64:266-275
Brain, behavior, and immunity 2017 Aug;64:266-275
Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.
Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Lopez D, Mehta R, Chen A, Liang D, Oakley A, Ihara M, Horsburgh K, Kalaria RN
Journal of neuroinflammation 2017 Apr 11;14(1):81
Journal of neuroinflammation 2017 Apr 11;14(1):81
PROTECTIVE EFFECTS OF ETHYL ACETATE EXTRACTION FROM GASTRODIA ELATA BLUME ON BLOOD-BRAIN BARRIER IN FOCAL CEREBRAL ISCHEMIA REPERFUSION.
He F, Duan X, Dai R, Wang W, Yang C, Lin Q
African journal of traditional, complementary, and alternative medicines : AJTCAM 2016;13(4):199-209
African journal of traditional, complementary, and alternative medicines : AJTCAM 2016;13(4):199-209
Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia.
Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJ, Washida K, Okamoto Y, Thomas AJ, Polvikoski TM, Allan LM, Oakley AE, O'Brien JT, Horsburgh K, Ihara M, Kalaria RN
Brain : a journal of neurology 2016 Jan;139(Pt 1):242-58
Brain : a journal of neurology 2016 Jan;139(Pt 1):242-58
Expression of aquaporin-4 and pathological characteristics of brain injury in a rat model of traumatic brain injury.
Zhang C, Chen J, Lu H
Molecular medicine reports 2015 Nov;12(5):7351-7
Molecular medicine reports 2015 Nov;12(5):7351-7
NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy.
Pecorelli A, Natrella F, Belmonte G, Miracco C, Cervellati F, Ciccoli L, Mariottini A, Rocchi R, Vatti G, Bua A, Canitano R, Hayek J, Forman HJ, Valacchi G
Biochimica et biophysica acta 2015 Mar;1852(3):507-19
Biochimica et biophysica acta 2015 Mar;1852(3):507-19
Visualization of inflammation and demyelination in 2D2 transgenic mice with rodent MRI.
Bell JC, Liu Q, Gan Y, Liu Q, Liu Y, Shi FD, Turner GH
Journal of neuroimmunology 2013 Nov 15;264(1-2):35-40
Journal of neuroimmunology 2013 Nov 15;264(1-2):35-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SKOV-3 cells were subjected to SDS PAGE followed by western blot with 16473-1-AP(AQP4 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16473-1-AP(AQP4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Aquaporin 4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Aquaporin 4. This antibody recognizes human,mouse,rat antigen. The Aquaporin 4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
