16473-1-AP

antibody from Proteintech Group

Targeting: AQP4 MIWC

Provider product page for 16473-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [77]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 16473-1-AP - Provider product page
Provider: Proteintech Group
Product name: Aquaporin 4 antibody
Antibody type: Polyclonal
Description: KD/KO validated Aquaporin 4 antibody (Cat. #16473-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

AQP4 protein structure - 16473-1-AP shown in red.

Submitted references Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice.

Deng S, Hu Y, Chen S, Xue Y, Yao D, Sun Q, Nedergaard M, Wang W, Ding F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Sep;44(9):1515-1531

A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.

Gao M, Liu Z, Zang H, Wu X, Yan Y, Lin H, Yuan J, Liu T, Zhou Y, Liu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Nov 1;30(21):4876-4886

The rhizomes of Atractylodes macrocephala Koidz improve gastrointestinal health and pregnancy outcomes in pregnant mice via modulating intestinal barrier and water-fluid metabolism.

Chenxing W, Jie S, Yajuan T, Ting L, Yuying Z, Suhong C, Guiyuan L
Journal of ethnopharmacology 2024 May 23;326:117971

Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.

Su Q, Su C, Zhang Y, Guo Y, Liu Y, Liu Y, Yong VW, Xue M
International immunopharmacology 2024 May 10;132:111962

Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.

Song Y, Xue T, Guo S, Yu Z, Yun C, Zhao J, Song Z, Liu Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306

NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.

Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300

White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.

Silbert LC, Roese NE, Krajbich V, Hurworth J, Lahna D, Schwartz DL, Dodge HH, Woltjer RL
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):3839-3851

Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system.

Wu X, Wen G, Yan L, Wang Y, Ren X, Li G, Luo Y, Shang J, Lu L, Hermenean A, Yao J, Li B, Lu Y, Wu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116739

Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice.

Wang S, Yu X, Cheng L, Ren W, Wen G, Wu X, Lou H, Ren X, Lu L, Hermenean A, Yao J, Li B, Lu Y, Wu X
Cell death & disease 2024 Jun 25;15(6):448

Ginkgolide B can alleviate spinal cord glymphatic system dysfunction and provide neuroprotection in painful diabetic neuropathy rats by inhibiting matrix metalloproteinase-9.

Li J, Jia S, Song Y, Xu W, Lin J
Neuropharmacology 2024 Jun 1;250:109907

Reduction of claudin-5 and aquaporin-4 in the rat hippocampal CA-1 and CA-3 regions of a learned helplessness model of depression.

Hirose Y, Oda Y, Yoshino K, Yano F, Kimura M, Kimura H, Iyo M, Shirayama Y
Pharmacology, biochemistry, and behavior 2024 Jan;234:173676

A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau.

Jiang Z, Wang J, Qin Y, Liu S, Luo B, Bai F, Wei H, Zhang S, Wei J, Ding G, Ma L, He S, Chen R, Sun Y, Chen Y, Wang L, Xu H, Wang X, Chen G, Lei W
Alzheimer's research & therapy 2024 Jan 27;16(1):22

TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.

Li X, Xie Z, Zhou Q, Tan X, Meng W, Pang Y, Huang L, Ding Z, Hu Y, Li R, Huang G, Li H
Molecular neurobiology 2024 Feb;61(2):1175-1186

Aquaporin 4 Mediates the Effect of Iron Overload on Hydrocephalus After Intraventricular Hemorrhage.

Li Y, Nan D, Liu R, Li J, Zhang Z, Deng J, Zhang Y, Yan Z, Hou C, Yao E, Sun W, Wang Z, Huang Y
Neurocritical care 2024 Feb;40(1):225-236

Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model.

Wen G, Zhan X, Xu X, Xia X, Jiang S, Ren X, Ren W, Lou H, Lu L, Hermenean A, Yao J, Gao L, Li B, Lu Y, Wu X
Molecular neurobiology 2024 Apr;61(4):2049-2062

Astrocytic Responses to Binge Alcohol Intake in the Mouse Hindbrain.

Hasegawa H, Kondo M
Biological & pharmaceutical bulletin 2023;46(9):1194-1202

The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts.

Fan Y, Yang Y, Lin K, Zhou X, Li Y, Lin Q
Open medicine (Warsaw, Poland) 2023;18(1):20230800

Functional Water Channels Within the TSH Receptor: A New Paradigm for TSH Action With Disease Implications.

Latif R, Davies TF, Mezei M
Endocrinology 2023 Sep 23;164(11)

Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism.

Perez Y, Velmeshev D, Wang L, White M, Siebert C, Baltazar J, Dutton NG, Wang S, Haeussler M, Chamberlain S, Kriegstein A
bioRxiv : the preprint server for biology 2023 Sep 22;

Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.

Yao D, Li R, Hao J, Huang H, Wang X, Ran L, Fang Y, He Y, Wang W, Liu X, Wang M
Translational psychiatry 2023 Oct 6;13(1):310

Glial Cell Adhesion Molecule (GlialCAM) Determines Proliferative versus Invasive Cell States in Glioblastoma.

De A, Lattier JM, Morales JE, Kelly JR, Zheng X, Chen Z, Sebastian S, Nassiri Toosi Z, Huse JT, Lang FF, McCarty JH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Nov 22;43(47):8043-8057

Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression.

Wang R, Peng L, Xiao Y, Zhou Q, Wang Z, Tang L, Xiao H, Yang K, Liu H, Li L
Cancer gene therapy 2023 May;30(5):716-726

Ganoderma lucidum polysaccharides ameliorates D-galactose-induced aging salivary secretion disorders by upregulating the rhythm and aquaporins.

Wu M, Huang B, Hu L, Zhang T, Zhang B, Zhao X, Lu R, Xiong W, Zhang S, Li J, Chen D, Yang B, Li G, Ran J
Experimental gerontology 2023 May;175:112147

Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.

Yao F, Luo Y, Chen Y, Li Y, Hu X, You X, Li Z, Yu S, Tian D, Zheng M, Cheng L, Jing J
Cellular and molecular neurobiology 2023 Mar;43(2):741-756

Effects of different dietary protein levels on intestinal aquaporins in weaned piglets.

Ren Z, Zhang X, Fan H, Yu Y, Yao S, Wang Y, Dong Y, Deng H, Zuo Z, Deng Y, Wang Y, Xu Z, Deng J
Journal of animal physiology and animal nutrition 2023 Mar;107(2):541-555

Experimental study on the effect of chlorhexidine gluconate (CG)-induced atrial fibrillation on renal water and sodium metabolism.

Li S, Pei H, Huang Y, Liu D, Yang L, Zhang Q, Wang Z
Scientific reports 2023 Mar 10;13(1):4016

A novel purgative mechanism of multiflorin A involves changing intestinal glucose absorption and permeability.

Zhao Z, Zuo X, Han C, Zhang Y, Zhao J, Wang Y, Zhang S, Li W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154805

High-titer AAV disrupts cerebrovascular integrity and induces lymphocyte infiltration in adult mouse brain.

Guo Y, Chen J, Ji W, Xu L, Xie Y, He S, Lai C, Hou K, Li Z, Chen G, Wu Z
Molecular therapy. Methods & clinical development 2023 Dec 14;31:101102

Klotho gene might antagonize ischemic injury in stroke rats by reducing the expression of AQP4 via P38MAPK pathway.

Zhu G, Xiang T, Liang S, Liu K, Xiao Z, Ye Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Aug;32(8):107205

Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.

Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050

Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.

Luo K, Wang Y, Chen WS, Feng X, Liao Y, Chen S, Liu Y, Liao C, Chen M, Ao L
Neural plasticity 2022;2022:5241449

S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.

Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948

Upregulation of TRPC6 inhibits astrocyte activation and proliferation after spinal cord injury in rats by suppressing AQP4 expression.

Cai J, Kong J, Ma S, Ban Y, Li J, Fan Z
Brain research bulletin 2022 Nov;190:12-21

Astrocytic p75(NTR) expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.

Qin X, Wang J, Chen S, Liu G, Wu C, Lv Q, He X, Bai X, Huang W, Liao H
Glia 2022 May;70(5):892-912

Strategies to Screen Anti-AQP4 Antibodies from Yeast Surface Display Libraries.

Huang A, Jin W, Fahad AS, Mussman BK, Nicchia GP, Madan B, de Souza MO, Griffin JD, Bennett JL, Frigeri A, Berkland CJ, DeKosky BJ
Antibodies (Basel, Switzerland) 2022 Jun 5;11(2)

Digoxin Ameliorates Glymphatic Transport and Cognitive Impairment in a Mouse Model of Chronic Cerebral Hypoperfusion.

Cao J, Yao D, Li R, Guo X, Hao J, Xie M, Li J, Pan D, Luo X, Yu Z, Wang M, Wang W
Neuroscience bulletin 2022 Feb;38(2):181-199

Akt/Aquaporin-4 Signaling Aggravates Neuropathic Pain by Activating Astrocytes after Spinal Nerve Ligation in Rats.

Guo S, Song Z, He J, Yin G, Zhu J, Liu H, Yang L, Ji X, Xu X, Liu Z, Liu J
Neuroscience 2022 Feb 1;482:116-131

Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway.

Zhang M, Zhang B, Chen R, Li M, Zheng Z, Xu W, Zhang Y, Gong S, Hu Q
Viruses 2022 Apr 18;14(4)

RNA-Seq Analysis Reveals Dendrobium officinale Polysaccharides Inhibit Precancerous Lesions of Gastric Cancer through PER3 and AQP4.

Zhao Y, Huang HX, Tang SY, Sun YZ
Evidence-based complementary and alternative medicine : eCAM 2021;2021:3036504

Attenuation of cerebral edema facilitates recovery of glymphatic system function after status epilepticus.

Liu K, Zhu J, Chang Y, Lin Z, Shi Z, Li X, Chen X, Lin C, Pan S, Huang K
JCI insight 2021 Sep 8;6(17)

Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder.

Ma X, Qin C, Chen M, Yu HH, Chu YH, Chen TJ, Bosco DB, Wu LJ, Bu BT, Wang W, Tian DS
Journal of neuroinflammation 2021 Sep 15;18(1):201

Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.

Xing C, Zhou Y, Xu H, Ding M, Zhang Y, Zhang M, Hu M, Huang X, Song L
Neuroscience research 2021 Oct;171:124-132

Effects of cannabinoid (CBD) on blood brain barrier permeability after brain injury in rats.

Jiang H, Li H, Cao Y, Zhang R, Zhou L, Zhou Y, Zeng X, Wu J, Wu D, Wu D, Guo X, Li X, Wu H, Li P
Brain research 2021 Oct 1;1768:147586

Reducing LncRNA-5657 expression inhibits the brain inflammatory reaction in septic rats.

Zhan YA, Qiu XL, Wang XZ, Zhao N, Qian KJ
Neural regeneration research 2021 Jul;16(7):1288-1293

Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes.

Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Perez Y, Mostajo-Radji MA, Wang S, Velmeshev D, Salma J, Kumar GR, Pollen AA, Crouch EE, Ott M, Kriegstein AR
bioRxiv : the preprint server for biology 2021 Jan 18;

Aquaporin 4 inhibition alleviates myocardial ischemia-reperfusion injury by restraining cardiomyocyte pyroptosis.

Jiang Q, Dong X, Hu D, Chen L, Luo Y
Bioengineered 2021 Dec;12(1):9021-9030

Haploinsufficiency of microglial MyD88 ameliorates Alzheimer's pathology and vascular disorders in APP/PS1-transgenic mice.

Quan W, Luo Q, Hao W, Tomic I, Furihata T, Schulz-Schäffer W, Menger MD, Fassbender K, Liu Y
Glia 2021 Aug;69(8):1987-2005

miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.

Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020

Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.

Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901

Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte.

Liu M, Xu Z, Wang L, Zhang L, Liu Y, Cao J, Fu Q, Liu Y, Li H, Lou J, Hou W, Mi W, Ma Y
Journal of neuroinflammation 2020 Sep 11;17(1):270

Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems.

Liu X, Hao J, Yao E, Cao J, Zheng X, Yao D, Zhang C, Li J, Pan D, Luo X, Wang M, Wang W
Brain, behavior, and immunity 2020 Oct;89:357-370

Effect of AQP4-RNAi in treating traumatic brain edema: Multi-modal MRI and histopathological changes of early stage edema in a rat model.

Guan Y, Li L, Chen J, Lu H
Experimental and therapeutic medicine 2020 Mar;19(3):2029-2036

Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.

Wang H, Chen H, Jin J, Liu Q, Zhong D, Li G
Life sciences 2020 Jun 15;251:117638

Higher expression levels of aquaporin (AQP)1 and AQP5 in the lungs of arid-desert living Lepus yarkandensis.

Zhang J, Li S, Liu J, Li L, Deng F, Baikeli B, Li L, Ma X, Liu G
Journal of animal physiology and animal nutrition 2020 Jul;104(4):1186-1195

Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation.

Shimizu M, Okuno T, Kinoshita M, Sumi H, Fujimura H, Yamashita K, Sugimoto T, Sakakibara S, Sakakibara K, Koda T, Tada S, Ishikura T, Murata H, Beppu S, Shiraishi N, Sugiyama Y, Nakatsuji Y, Kumanogoh A, Mochizuki H
Scientific reports 2020 Aug 6;10(1):13274

Higher Expression Levels of Aquaporin Family of Proteins in the Kidneys of Arid-Desert Living Lepus yarkandensis.

Zhang J, Li S, Deng F, Baikeli B, Huang S, Wang B, Liu G
Frontiers in physiology 2019;10:1172

Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.

He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260

Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.

Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G
Scientific reports 2019 Nov 12;9(1):16639

PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1.

Huang B, Miao H, Yuan Y, Qiu F, Liu X, Liu Z, Zhang H, Zhao Q, Wang M, Dong H, Zhang Z
International journal of molecular medicine 2019 May;43(5):1979-1990

Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice.

Fang Y, Tian Y, Huang Q, Wan Y, Xu L, Wang W, Pan D, Zhu S, Xie M
Journal of neuroinflammation 2019 May 9;16(1):96

Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production.

Cotzomi E, Stathopoulos P, Lee CS, Ritchie AM, Soltys JN, Delmotte FR, Oe T, Sng J, Jiang R, Ma AK, Vander Heiden JA, Kleinstein SH, Levy M, Bennett JL, Meffre E, O'Connor KC
Brain : a journal of neurology 2019 Jun 1;142(6):1598-1615

Severe white matter astrocytopathy in CADASIL.

Hase Y, Chen A, Bates LL, Craggs LJL, Yamamoto Y, Gemmell E, Oakley AE, Korolchuk VI, Kalaria RN
Brain pathology (Zurich, Switzerland) 2018 Nov;28(6):832-843

TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types.

Khalfallah Y, Kuta R, Grasmuck C, Prat A, Durham HD, Vande Velde C
Scientific reports 2018 May 15;8(1):7551

All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.

Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296

2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.

Zhang Z, Zhang L, Chen J, Cao Y, Qu M, Lin X, Han Z, Ji X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489

Aquaporin 4 Silencing Aggravates Hydrocephalus Induced by Injection of Autologous Blood in Rats.

Guo J, Mi X, Zhan R, Li M, Wei L, Sun J
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 20;24:4204-4212

Role of vasodilator-stimulated phosphoprotein in human cytomegalovirus-induced hyperpermeability of human endothelial cells.

Tian Y, He Y, Zhang L, Zhang J, Xu L, Ma Y, Xu X, Wei L
Experimental and therapeutic medicine 2018 Aug;16(2):1295-1303

A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.

Zhang DD, Zou MJ, Zhang YT, Fu WL, Xu T, Wang JX, Xia WR, Huang ZG, Gan XD, Zhu XM, Xu DG
Experimental neurology 2017 Nov;297:1-13

Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.

Shepard MJ, Padmanaban V, Edwards NA, Chittiboina P, Ray-Chaudhury A, Heiss JD
World neurosurgery 2017 Nov;107:1046.e1-1046.e7

Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.

He F, Duan X, Dai R, Li Y, Lin Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265

Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice.

Zhou Y, Huang X, Zhao T, Qiao M, Zhao X, Zhao M, Xu L, Zhao Y, Wu L, Wu K, Chen R, Fan M, Zhu L
Brain, behavior, and immunity 2017 Aug;64:266-275

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.

Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Lopez D, Mehta R, Chen A, Liang D, Oakley A, Ihara M, Horsburgh K, Kalaria RN
Journal of neuroinflammation 2017 Apr 11;14(1):81

PROTECTIVE EFFECTS OF ETHYL ACETATE EXTRACTION FROM GASTRODIA ELATA BLUME ON BLOOD-BRAIN BARRIER IN FOCAL CEREBRAL ISCHEMIA REPERFUSION.

He F, Duan X, Dai R, Wang W, Yang C, Lin Q
African journal of traditional, complementary, and alternative medicines : AJTCAM 2016;13(4):199-209

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia.

Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJ, Washida K, Okamoto Y, Thomas AJ, Polvikoski TM, Allan LM, Oakley AE, O'Brien JT, Horsburgh K, Ihara M, Kalaria RN
Brain : a journal of neurology 2016 Jan;139(Pt 1):242-58

Expression of aquaporin-4 and pathological characteristics of brain injury in a rat model of traumatic brain injury.

Zhang C, Chen J, Lu H
Molecular medicine reports 2015 Nov;12(5):7351-7

NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy.

Pecorelli A, Natrella F, Belmonte G, Miracco C, Cervellati F, Ciccoli L, Mariottini A, Rocchi R, Vatti G, Bua A, Canitano R, Hayek J, Forman HJ, Valacchi G
Biochimica et biophysica acta 2015 Mar;1852(3):507-19

Visualization of inflammation and demyelination in 2D2 transgenic mice with rodent MRI.

Bell JC, Liu Q, Gan Y, Liu Q, Liu Y, Shi FD, Turner GH
Journal of neuroimmunology 2013 Nov 15;264(1-2):35-40

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: SKOV-3 cells were subjected to SDS PAGE followed by western blot with 16473-1-AP(AQP4 antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human brain using 16473-1-AP(AQP4 antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Aquaporin 4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Aquaporin 4. This antibody recognizes human,mouse,rat antigen. The Aquaporin 4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 16473-1-AP.pdf

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