Tissue expression
Cell line expression

PTPRU

gene product
FMI, hPTP-J, PCP-2, PTP, PTPRO 
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
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Antibodies

 

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42 antibodies from 17 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
4 antibodies
LifeSpan BioSciences, Inc.
13 antibodies
Affinity Biosciences
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
antibodies-online
8 antibodies
Novus Biologicals
2 antibodies
St John's Laboratory
2 antibodies
Abnova Corporation
1 antibody
Atlas Antibodies
1 antibody
R&D Systems
1 antibody
MilliporeSigma / Merck KGaA
2 antibodies
Biorbyt
1 antibody
Creative Diagnostics
1 antibody
MyBioSource
1 antibody
Abbexa
1 antibody
Creative Biolabs
1 antibody