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LearnTissue expression
Cell line expression
Protein structure
SH2B2
SH2B adaptor protein 2APS
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009]
Top validated antibodies |
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| antibodies-online |  ABIN2505364 |
Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-17608 |
1 references | Polyclonal |
WB
IHC
OA
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| Novus Biologicals | NBP2-13305 |
Polyclonal |
WB
ICC
IHC
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| Atlas Antibodies | HPA051131 |
Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C805414 |
Polyclonal |
WB
EL
ICC
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