Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13037-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13037-1-AP, RRID:AB_10640800
- Product name
- TRIM37 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRIM37 antibody (Cat. #13037-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRIM37 regulates HMGB1 ubiquitination to inhibit ferroptosis in Schwann cells and alleviate peripheral nerve injury.
Dynamic regulation of K33- and K48-linked ubiquitination of Tip60 by TRIM37 orchestrates host DNA damage response during Pseudomonas aeruginosa infection and recovery.
TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models.
HNRNPA1 promotes TRIM37 mRNA stability and mediates TRAF6 ubiquitination to alleviate osteoarthritis.
KIFC1 depends on TRIM37-mediated ubiquitination of PLK4 to promote centrosome amplification in endometrial cancer.
TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.
TRIM37 promotes gallbladder cancer proliferation by activating the Wnt/β-catenin pathway via ubiquitination of Axin1.
TRIM37 exacerbates hepatic ischemia/reperfusion injury by facilitating IKKγ translocation.
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
The TRIM37 variants in Mulibrey nanism patients paralyze follicular helper T cell differentiation.
Aerobic glycolysis and tumor progression of hepatocellular carcinoma are mediated by ubiquitin of P53 K48-linked regulated by TRIM37.
Tripartite motif containing protein 37 involves in thrombin stimulated BV-2 microglial cell apoptosis and interleukin 1β release.
Zhou X, You Y, Zhong L, Peng W, Yang Y, Qi J
Brain research bulletin 2026 Jan;234:111701
Brain research bulletin 2026 Jan;234:111701
Dynamic regulation of K33- and K48-linked ubiquitination of Tip60 by TRIM37 orchestrates host DNA damage response during Pseudomonas aeruginosa infection and recovery.
Yu H, Wang X, Xiong J, He X, Ma C, Wang Q, Chen R, Li Y, Dai Q, Min Q, Zhou J, Zhang K
Microbiological research 2026 Apr;305:128414
Microbiological research 2026 Apr;305:128414
TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models.
Jiang L, Jin Y, Han Y, Fu J
PloS one 2025;20(10):e0335198
PloS one 2025;20(10):e0335198
HNRNPA1 promotes TRIM37 mRNA stability and mediates TRAF6 ubiquitination to alleviate osteoarthritis.
Deng H, Liu W, Xiang L, Wu J
International immunopharmacology 2025 Dec 3;166:115568
International immunopharmacology 2025 Dec 3;166:115568
KIFC1 depends on TRIM37-mediated ubiquitination of PLK4 to promote centrosome amplification in endometrial cancer.
Zhou K, He Y, Lin X, Zhou H, Xu X, Xu J
Cell death discovery 2024 Sep 30;10(1):419
Cell death discovery 2024 Sep 30;10(1):419
TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.
Qin Y, Chen L, Zhu W, Song J, Lin J, Li Y, Zhang J, Song X, Xing T, Guo T, Duan X, Zhang Y, Ruan E, Wang Q, Li B, Yang W, Yin P, Yan XX, Li S, Li XJ, Yang S
Science advances 2024 May 17;10(20):eadl2036
Science advances 2024 May 17;10(20):eadl2036
TRIM37 promotes gallbladder cancer proliferation by activating the Wnt/β-catenin pathway via ubiquitination of Axin1.
Xu M, Jiang B, Man Z, Zhu H
Translational oncology 2023 Sep;35:101732
Translational oncology 2023 Sep;35:101732
TRIM37 exacerbates hepatic ischemia/reperfusion injury by facilitating IKKγ translocation.
Yang H, Huang Z, Luo Y, Lei D, Yan P, Shen A, Liu W, Li D, Wu Z
Molecular medicine (Cambridge, Mass.) 2023 May 8;29(1):62
Molecular medicine (Cambridge, Mass.) 2023 May 8;29(1):62
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
Liao X, Li Z, Zheng H, Qian W, Zhang S, Chen S, Li X, Tang M, Xu Y, Yu R, Li M, Song L, Li J
Molecular cancer research : MCR 2023 Jul 5;21(7):648-663
Molecular cancer research : MCR 2023 Jul 5;21(7):648-663
The TRIM37 variants in Mulibrey nanism patients paralyze follicular helper T cell differentiation.
Gu W, Zhang J, Li Q, Zhang Y, Lin X, Wu B, Yin Q, Sun J, Lu Y, Sun X, Jia C, Li C, Zhang Y, Wang M, Yin X, Wang S, Xu J, Wang R, Zhu S, Cheng S, Chen S, Liu L, Zhu L, Yan C, Yi C, Li X, Lian Q, Lin G, Ling Z, Ma L, Zhou M, Xiao K, Wei H, Hu R, Zhou W, Ye L, Wang H, Li J, Sun B
Cell discovery 2023 Aug 1;9(1):82
Cell discovery 2023 Aug 1;9(1):82
Aerobic glycolysis and tumor progression of hepatocellular carcinoma are mediated by ubiquitin of P53 K48-linked regulated by TRIM37.
Ge Y, Zhao R, Li B, Xiao B, Zhou L, Zuo S
Experimental cell research 2022 Dec 15;421(2):113377
Experimental cell research 2022 Dec 15;421(2):113377
Tripartite motif containing protein 37 involves in thrombin stimulated BV-2 microglial cell apoptosis and interleukin 1β release.
Han C, Xia X, Jiao S, Li G, Ran Q, Yao S
Biochemical and biophysical research communications 2019 Sep 3;516(4):1252-1257
Biochemical and biophysical research communications 2019 Sep 3;516(4):1252-1257
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The TRIM37 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRIM37. This antibody recognizes human, mouse, rat antigen. The TRIM37 antibody has been validated for the following applications: ELISA, WB analysis.