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Protein structure
DSE
Dermatan sulfate epimeraseDS-Epi1, DSEPI, SART2
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]
Top validated antibodies |
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| antibodies-online |  ABIN396720 |
5 references | Monoclonal |
WB
EL
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| Proteintech Group | 60041-1-Ig |
1 references | Monoclonal |
WB
EL
IHC
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| Atlas Antibodies | HPA014764 |
2 references | Polyclonal |
ICC
IHC
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| NovoPro Bioscience Inc. | 107242 |
Monoclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA890925LA01HU |
Polyclonal |
EL
ICC
IHC
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