20592-1-AP
antibody from Proteintech Group
Targeting: ORAI2
C7orf19, CBCIP2, FLJ12474, FLJ14733, H_NH0514P08.8, TMEM142B
Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 20592-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ORAI2 antibody
- Antibody type
- Polyclonal
- Description
- ORAI2 antibody (Cat. #20592-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tibial cortex transverse transport regulates Orai1/STIM1-mediated NO release and improve the migration and proliferation of vessels via increasing osteopontin expression.
Exercise Reduces Airway Smooth Muscle Contraction in Asthmatic Rats via Inhibition of IL-4 Secretion and Store-Operated Ca(2+) Entry Pathway.
Bisbenzylisoquinoline alkaloids from Plumula Nelumbinis inhibit vascular smooth muscle cells migration and proliferation by regulating the ORAI2/Akt pathway.
X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca(2+) Influx in Rat Brain Microvascular Endothelial Cells.
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Orai-vascular endothelial-cadherin signaling complex regulates high-glucose exposure-induced increased permeability of mouse aortic endothelial cells.
Cardiac-Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice.
Kong L, Li Y, Deng Z, Chen X, Xia Y, Shen B, Ning R, Zhang L, Yin Z
Journal of orthopaedic translation 2024 Mar;45:107-119
Journal of orthopaedic translation 2024 Mar;45:107-119
Exercise Reduces Airway Smooth Muscle Contraction in Asthmatic Rats via Inhibition of IL-4 Secretion and Store-Operated Ca(2+) Entry Pathway.
Huang JH, Gao HW, Gao DD, Yang WY, Zhao MK, Shen B, Hu M
Allergy, asthma & immunology research 2023 May;15(3):361-373
Allergy, asthma & immunology research 2023 May;15(3):361-373
Bisbenzylisoquinoline alkaloids from Plumula Nelumbinis inhibit vascular smooth muscle cells migration and proliferation by regulating the ORAI2/Akt pathway.
Feng X, Xie B, Han Y, Li Z, Cheng Y, Tian LW
Phytochemistry 2023 Jul;211:113700
Phytochemistry 2023 Jul;211:113700
X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca(2+) Influx in Rat Brain Microvascular Endothelial Cells.
Xu F, Wang Y, Gao H, Zhang X, Hu Y, Han T, Shen B, Zhang L, Wu Q
Frontiers in molecular biosciences 2021;8:646730
Frontiers in molecular biosciences 2021;8:646730
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Lele W, Lei L, Liting Q
Experimental and therapeutic medicine 2021 Jun;21(6):587
Experimental and therapeutic medicine 2021 Jun;21(6):587
Orai-vascular endothelial-cadherin signaling complex regulates high-glucose exposure-induced increased permeability of mouse aortic endothelial cells.
Wei Y, Bai S, Yao Y, Hou W, Zhu J, Fang H, Du Y, He W, Shen B, Du J
BMJ open diabetes research & care 2021 Apr;9(1)
BMJ open diabetes research & care 2021 Apr;9(1)
Cardiac-Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice.
Gammons J, Trebak M, Mancarella S
Journal of the American Heart Association 2021 Apr 20;10(8):e019486
Journal of the American Heart Association 2021 Apr 20;10(8):e019486
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF-7 cells were subjected to SDS PAGE followed by western blot with 20592-1-AP( ORAI2 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HEK-293 cells using 20592-1-AP( ORAI2 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ORAI2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ORAI2. This antibody recognizes human, mouse antigen. The ORAI2 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.